Extraction equipment for intestinal flora transplantation

By designing an integrated mixing and separation device that operates in parallel, efficient and continuous extraction of gut microbiota was achieved, solving the problems of incomplete extraction and low efficiency in traditional equipment, and improving the purity and efficiency of gut microbiota extraction.

CN223963491UActive Publication Date: 2026-03-03FOURTH MILITARY MEDICAL UNIVERSITY
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Patent Information

Application Number
CN202520520355.7
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-03-24
Publication Date
2026-03-03
Estimated Expiration
2035-03-24

AI Technical Summary

Technical Problem

Traditional intestinal flora extraction equipment requires multiple equipment replacements, making continuous processing difficult. Uneven mixing leads to incomplete extraction and may introduce contamination, reducing extraction efficiency and purity.

Method used

Design an extraction device for intestinal flora transplantation, which adopts a parallel operation of stirring and separation. The stirring component mixes fecal material and solvent, and the centrifugal force of the separation cylinder is used to separate intestinal flora from impurities. Light bacteria flow out through the separation hole, while heavy impurities remain in the cylinder, achieving efficient and continuous extraction.

Benefits of technology

It significantly improves the efficiency and purity of gut microbiota extraction. Through parallel operation design, it enhances the overall processing efficiency and ensures the continuity and high efficiency of extraction.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of intestinal flora transplantation and extraction equipment, in particular to extraction equipment for intestinal flora transplantation, which comprises a frame, a controller, a stirring tank, a rotating shaft, a rotating seat, a separating tank, a separating cylinder, a separating hole, a stirring component, a driving component, a feeding component, a conveying component and a discharging component. A separating tank is arranged in the lower portion of the frame, a rotating shaft is arranged in the separating tank, a rotating seat is arranged at the upper end of the rotating shaft, a separating cylinder is arranged above the rotating seat, multiple sets of separating holes are formed in the side wall of the separating cylinder, the upper end of the conveying assembly is arranged on the bottom wall of the stirring tank, and a driving assembly is arranged on the bottom wall of the frame. A controller is arranged on the side wall of the frame, in the using process of the intestinal flora transplantation and extraction equipment, efficient and continuous extraction of intestinal flora is achieved through highly-integrated stirring and separation integrated design, and the working efficiency is greatly improved.
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Description

Technical Field

[0001] This utility model relates to the technical field of intestinal flora transplantation extraction equipment, and in particular to an extraction device for intestinal flora transplantation. Background Technology

[0002] As an important micro-ecosystem in the human body, the gut microbiota plays a vital role in maintaining human health. They participate in multiple physiological processes such as food digestion, nutrient absorption, immune regulation, and defense against pathogen invasion. However, in clinical practice, research and treatment of gut microbiota often face many challenges.

[0003] In practical applications, traditional intestinal flora extraction often involves using a mechanical homogenizer to mix fecal samples with a solvent, followed by separation of the intestinal flora through centrifugation or filtration. This process requires multiple equipment changes, making continuous processing difficult. Inconsistent mixing of fecal samples and solvents leads to incomplete extraction of intestinal flora. Furthermore, the separation step often relies on cumbersome and inefficient centrifugation techniques, which not only affect extraction efficiency but may also introduce contamination, reducing the purity of the extract. These issues urgently require improvement, hindering the efficient and continuous extraction of intestinal flora.

[0004] Therefore, to address the aforementioned problem of inconvenience in achieving efficient and continuous extraction of gut microbiota, an extraction device for gut microbiota transplantation can be designed. During the use of this extraction device, the stirring and separation steps are designed to operate in parallel. That is, while the previous batch of gut microbiota is being separated, the mixing of the next batch of fecal material with the solvent can be carried out simultaneously, achieving efficient and continuous extraction of gut microbiota and greatly improving work efficiency. Utility Model Content

[0005] To overcome the challenges of using a gut microbiota transplantation extraction device, traditional gut microbiota extraction methods often involve mechanically homogenizing fecal samples with solvents, followed by separation of gut microbiota through centrifugation or filtration. This process requires multiple equipment changes, hindering continuous processing. Incomplete mixing of fecal samples and solvents leads to incomplete extraction. Furthermore, the separation process often relies on cumbersome and inefficient centrifugation techniques, which not only affect extraction efficiency but may also introduce contamination, reducing the purity of the extract. Therefore, improvements are urgently needed to address the problem of inefficient and continuous extraction of gut microbiota.

[0006] The technical solution of this utility model is as follows: an extraction device for intestinal flora transplantation, comprising a frame, a controller, a mixing tank, a rotating shaft, a rotating seat, a separation tank, a separation cylinder, separation holes, a mixing component, a driving component, a feeding component, a conveying component, and a discharging component. The mixing tank is arranged inside the upper part of the frame, and two sets of feeding components are arranged on the upper sides of the mixing tank. The mixing component is arranged inside the mixing tank. The separation tank is arranged inside the lower part of the frame, and a rotating shaft is arranged inside the separation tank. A rotating seat is arranged at the upper end of the rotating shaft, and a separation cylinder is arranged above the rotating seat. Multiple sets of separation holes are opened on the side wall of the separation cylinder. A conveying component is arranged above the separation tank, and the upper end of the conveying component is arranged on the bottom wall of the mixing tank. A driving component is arranged on the bottom wall of the frame. A discharging component is arranged on one side of the bottom of the separation tank. A controller is arranged on the side wall of the frame.

[0007] Preferably, during the use of the intestinal flora transplantation extraction equipment, the operator first adds the fecal material to be processed and the required solvent into the mixing tank through the feeding component. Then, the controller activates the drive component, which drives the mixing component to rotate at high speed within the mixing tank, ensuring thorough and uniform mixing of the fecal material and solvent. Simultaneously, the drive component also drives the rotating seat and separation cylinder to rotate. Once the fecal material and solvent are uniformly mixed, the mixture is smoothly introduced into the separation cylinder through the conveying component. At this point, the rotation of the separation cylinder generates a strong centrifugal force, forcing the intestinal flora to separate from impurities due to density differences. In this process, the lighter intestinal flora is thrown against the wall of the separation cylinder and flows out through the pre-designed separation holes, while heavier impurities remain inside the cylinder. As the separation process continues, the separated intestinal flora is finally discharged smoothly through the discharge component, completing the extraction. In addition, the stirring and separation steps of this equipment are designed to operate in parallel, meaning that while the previous batch of intestinal flora is being separated, the mixing of the next batch of fecal material with the solvent can be carried out simultaneously, significantly improving the overall processing efficiency. In summary, this equipment, through its highly integrated stirring and separation design, achieves efficient and continuous extraction of intestinal flora, greatly improving work efficiency.

[0008] Preferably, the stirring assembly includes a stirring shaft and stirring rods. The stirring shaft is installed inside the stirring tank, and stirring rods are installed on the side wall of the stirring shaft. Multiple sets of stirring rods are provided.

[0009] Preferably, the drive assembly includes a drive motor, a drive shaft, and a drive wheel. The drive motor is mounted on the bottom wall of the frame, the drive shaft is mounted on the output end of the drive motor, the drive wheel is mounted on the side wall of the drive shaft, and the upper end of the drive shaft is fixedly connected to the lower end of the stirring shaft.

[0010] Preferably, the drive assembly also includes a driven shaft, a driven pulley, and a drive belt. The driven shaft is located at the lower end of the rotating shaft, the driven pulley is located on the side wall of the driven shaft, the drive belt is located outside the driving pulley, the driving pulley is rotatably connected to the drive belt, and the driven pulley is located inside the drive belt and is rotatably connected to the drive belt.

[0011] Preferably, the feeding assembly includes a main feed pipe and an auxiliary feed pipe, with the main feed pipe located on the upper side of one side of the mixing tank and the auxiliary feed pipe located on the other side of the mixing tank.

[0012] Preferably, the conveying assembly includes a conveying pipe and a conveying valve. The conveying pipe is located above the separation tank, and the conveying valve is located on the side wall of the conveying pipe. The upper end of the conveying pipe is located on the bottom wall of the mixing tank, and the other end of the conveying pipe is located above the separation cylinder.

[0013] Preferably, the discharge assembly includes a discharge pipe, a discharge valve, and a collection tank. The discharge pipe is provided on one side of the bottom of the separation tank, the discharge valve is provided on the side wall of the discharge pipe, and the collection tank is provided on one side of the frame.

[0014] The beneficial effects of this utility model are:

[0015] During the use of the gut microbiota transplantation extraction equipment, the operator first adds the fecal material to be processed and the required solvent into the mixing tank through the feeding component. Then, the controller activates the drive component, which drives the mixing component to rotate at high speed within the mixing tank, ensuring thorough and uniform mixing of the fecal material and solvent. Simultaneously, the drive component also drives the rotating seat and separation cylinder to rotate. Once the fecal material and solvent are uniformly mixed, the mixture is smoothly introduced into the separation cylinder through the conveying component. At this point, the rotation of the separation cylinder generates a strong centrifugal force, forcing the gut microbiota to separate from impurities due to density differences. Lighter intestinal flora are thrown against the wall of the separation cylinder and flow out through pre-designed separation holes, while heavier impurities remain inside the cylinder. As the separation process continues, the separated intestinal flora is finally discharged smoothly through the discharge assembly, completing the extraction. In addition, the stirring and separation steps of this equipment are designed to operate in parallel, meaning that while the previous batch of intestinal flora is being separated, the mixing of the next batch of fecal material with the solvent can be carried out simultaneously, significantly improving the overall processing efficiency. In summary, this equipment, through its highly integrated stirring and separation design, achieves efficient and continuous extraction of intestinal flora, greatly improving work efficiency. Attached Figure Description

[0016] Figure 1 The diagram shown is a first three-dimensional structural schematic of an extraction device for intestinal flora transplantation according to this utility model.

[0017] Figure 2The diagram shown is a partial three-dimensional structural schematic of an extraction device for intestinal flora transplantation according to the present invention.

[0018] Figure 3 The diagram shown is a partial three-dimensional structural schematic of an extraction device for intestinal flora transplantation according to the present invention.

[0019] Figure 4 The diagram shown is a three-dimensional structural schematic of the third part of an extraction device for intestinal flora transplantation according to this utility model.

[0020] Explanation of reference numerals in the attached drawings: 1. Frame; 2. Controller; 3. Mixing tank; 4. Rotating shaft; 5. Rotating seat; 6. Separating tank; 7. Separating cylinder; 8. Separating hole; 101. Mixing shaft; 102. Mixing rod; 201. Drive motor; 202. Drive shaft; 203. Drive wheel; 204. Driven shaft; 205. Driven wheel; 206. Drive belt; 301. Main material pipe; 302. Auxiliary material pipe; 401. Conveying pipe; 402. Conveying valve; 501. Discharge pipe; 502. Discharge valve; 503. Collection tank. Detailed Implementation

[0021] The present invention will be further described below with reference to the accompanying drawings and embodiments.

[0022] Please see Figure 1 and Figure 2 This utility model provides an embodiment of an extraction device for intestinal flora transplantation, comprising a frame 1, a controller 2, a mixing tank 3, a rotating shaft 4, a rotating seat 5, a separation tank 6, a separation cylinder 7, separation holes 8, a mixing assembly, a driving assembly, a feeding assembly, a conveying assembly, and a discharging assembly. The mixing tank 3 is disposed inside the upper part of the frame 1, and two sets of feeding assemblies are disposed on both sides of the upper part of the mixing tank 3. The mixing assembly is disposed inside the mixing tank 3. The separation tank 6 is disposed inside the lower part of the frame 1, and the rotating shaft 4 is disposed inside the separation tank 6. The rotating seat 5 is disposed at the upper end of the rotating shaft 4, and the separation cylinder 7 is disposed above the rotating seat 5. Multiple sets of separation holes 8 are opened on the side wall of the separation cylinder 7. The conveying assembly is disposed above the separation tank 6, and the upper end of the conveying assembly is disposed on the bottom wall of the mixing tank 3. The driving assembly is disposed on the bottom wall of the frame 1. The discharging assembly is disposed on one side of the bottom of the separation tank 6. The controller 2 is disposed on the side wall of the frame 1.

[0023] Please see Figure 2 and Figure 3The mixing assembly includes a mixing shaft 101 and mixing rods 102. The mixing tank 3 has a mixing shaft 101 inside, and mixing rods 102 are mounted on the side wall of the mixing shaft 101. Multiple sets of mixing rods 102 are provided, and the mixing shaft 101 can drive multiple sets of mixing rods 102 to rotate, ensuring thorough and uniform mixing of the manure and solvent. The drive assembly includes a drive motor 201, a drive shaft 202, and a drive wheel 203. The drive motor 201 is mounted on the bottom wall of the frame 1, and the output end of the drive motor 201 has a drive shaft 202. The drive wheel 203 is mounted on the side wall of the drive shaft 202. The upper end of the drive shaft 202 is fixedly connected to the lower end of the mixing shaft 101. The main... The motor 201 can drive the drive wheel 203 to rotate via the drive shaft 202. The drive assembly also includes a driven shaft 204, a driven wheel 205, and a transmission belt 206. The driven shaft 204 is provided at the lower end of the rotating shaft 4. The driven wheel 205 is provided on the side wall of the driven shaft 204. The transmission belt 206 is provided on the outside of the drive wheel 203. The drive wheel 203 is rotatably connected to the transmission belt 206. The driven wheel 205 is provided inside the transmission belt 206. The driven wheel 205 is rotatably connected to the transmission belt 206. The drive wheel can drive the transmission belt 206 to rotate. The transmission belt 206 can drive the driven shaft 204 to rotate via the driven wheel 205.

[0024] Please see Figure 3 and Figure 4 The feeding assembly includes a main feed pipe 301 and an auxiliary feed pipe 302. The main feed pipe 301 is located on the upper side of one side of the mixing tank 3, and the auxiliary feed pipe 302 is located on the other side of the mixing tank 3. The operator adds the manure to be processed into the mixing tank 3 through the main feed pipe 301, and adds the required solvent into the mixing tank 3 through the auxiliary feed pipe 302. The conveying assembly includes a conveying pipe 401 and a conveying valve 402. The conveying pipe 401 is located on the upper side of the separation tank 6, and the conveying valve 402 is located on the side wall of the conveying pipe 401. The upper end of the conveying pipe 401 is located on the bottom wall of the mixing tank 3. The other end of the conveying pipe 401 is located above the separation cylinder 7. The controller 2 controls the opening of the conveying valve 402 on the conveying pipe 401, and the mixture is smoothly introduced into the separation cylinder 7. The discharge assembly includes a discharge pipe 501, a discharge valve 502, and a collection tank 503. The discharge pipe 501 is located on one side of the bottom of the separation tank 6, and the discharge valve 502 is located on the side wall of the discharge pipe 501. The collection tank 503 is located on one side of the frame 1. The controller 2 opens the discharge valve 502 at an appropriate time, so that the separated intestinal flora flows smoothly into the collection tank 503 along the discharge pipe 501, completing the extraction.

[0025] When the intestinal flora transplantation extraction equipment is in use, the operator first adds the fecal material to be processed into the mixing tank 3 through the main feed pipe 301, and then adds the required solvent into the mixing tank 3 through the auxiliary feed pipe 302.

[0026] Subsequently, controller 2 activates the drive motor 201, whose power is directly transmitted to the stirring shaft 101 via the drive shaft 202, driving the multiple sets of stirring rods 102 mounted on it to rotate at high speed inside the mixing tank 3, ensuring that the manure and solvent are fully and evenly mixed.

[0027] Meanwhile, the drive wheel 203 on the drive shaft 202 is connected to the driven wheel 205 via the transmission belt 206. When the drive motor 201 works, the driven wheel 205 also rotates, further driving the driven shaft 204 and its rotating seat 5 and separating cylinder 7 to rotate. Once the manure and solvent are evenly mixed, the controller 2 controls the conveying valve 402 on the conveying pipe 401 to open, and the mixture is smoothly introduced into the separating cylinder 7.

[0028] At this point, the rotation of the separation cylinder 7 generates a strong centrifugal force, forcing the intestinal flora to separate from the impurities due to their density difference. The lighter intestinal flora is thrown against the wall of the separation cylinder 7 and flows out through the pre-designed separation holes 8, while the heavier impurities remain inside the cylinder.

[0029] As the separation process continues, controller 2 opens discharge valve 502 at appropriate times, allowing the separated intestinal flora to flow smoothly into collection tank 503 along discharge pipe 501, completing the extraction. Furthermore, the mixing and separation steps of this equipment are designed to operate in parallel, meaning that while the previous batch of intestinal flora is being separated, the mixing of the next batch of feces with the solvent can proceed simultaneously, significantly improving overall processing efficiency.

[0030] In summary, this equipment, through its highly integrated design of stirring and separation, achieves efficient and continuous extraction of intestinal flora, greatly improving work efficiency.

[0031] Through the above steps, when the intestinal flora transplantation extraction equipment is in use, firstly, the operator adds the fecal material to be processed and the required solvent into the mixing tank 3 through the feeding component. Then, the controller 2 activates the drive component, which drives the mixing component to rotate at high speed within the mixing tank 3, ensuring thorough and uniform mixing of the fecal material and solvent. Simultaneously, the drive component drives the rotating seat 5 and the separation cylinder 7 to rotate. Once the fecal material and solvent are uniformly mixed, the mixture is smoothly introduced into the separation cylinder 7 through the conveying component. At this point, the rotation of the separation cylinder 7 generates a strong centrifugal force, forcing the intestinal flora and impurities to separate due to density differences. The system separates the intestinal flora based on their differences. Lighter intestinal flora are thrown against the wall of the separation cylinder 7 and flow out through the pre-designed separation holes 8, while heavier impurities remain inside the cylinder. As the separation process continues, the separated intestinal flora is finally discharged smoothly through the discharge assembly, completing the extraction. In addition, the mixing and separation steps of this equipment are designed to operate in parallel, meaning that while the previous batch of intestinal flora is being separated, the mixing of the next batch of fecal material with the solvent can be carried out simultaneously, significantly improving the overall processing efficiency. In summary, this equipment, through its highly integrated mixing and separation design, achieves efficient and continuous extraction of intestinal flora, greatly improving work efficiency.

[0032] The embodiments of the present invention have been described in detail above with reference to the accompanying drawings. However, the present invention is not limited to the above embodiments. Within the scope of knowledge possessed by those skilled in the art, various changes can be made without departing from the spirit of the present invention.

Claims

1. An extraction device for fecal microbiota transplantation, comprising a frame (1), a controller (2), characterized in that: Also include the stirring tank (3), rotating shaft (4), rotating seat (5), separation tank (6), separation cylinder (7), separation hole (8), stirring assembly, driving assembly, feeding assembly, feeding assembly and discharge assembly, the upper inside of frame (1) is provided with stirring tank (3), both sides of stirring tank (3) are provided with two groups of feeding assembly, the inside of stirring tank (3) is provided with stirring assembly, the lower inside of frame (1) is provided with separation tank (6), the inside of separation tank (6) is provided with rotating shaft (4), the upper end of rotating shaft (4) is provided with rotating seat (5), the upper of rotating seat (5) is provided with separation cylinder (7), a plurality of separation holes (8) are formed in the side wall of separation cylinder (7), the upper of separation tank (6) is provided with feeding assembly, the upper end of feeding assembly is provided on the bottom wall of stirring tank (3), the bottom wall of frame (1) is provided with driving assembly, the bottom side of separation tank (6) is provided with discharge assembly, the sidewall of frame (1) is provided with controller (2).

2. The extraction device for fecal microbiota transplantation according to claim 1, characterized in that: The stirring assembly includes a stirring shaft (101) and a stirring rod (102), the inside of the stirring tank (3) is provided with a stirring shaft (101), the sidewall of the stirring shaft (101) is provided with a stirring rod (102), and the stirring rod (102) is provided with a plurality of groups.

3. The extraction device for fecal microbiota transplantation according to claim 1, characterized in that: The driving assembly includes a driving motor (201), a driving shaft (202) and a driving wheel (203), the bottom wall of the frame (1) is provided with a driving motor (201), the output end of the driving motor (201) is provided with a driving shaft (202), the sidewall of the driving shaft (202) is provided with a driving wheel (203), and the upper end of the driving shaft (202) is fixedly connected with the lower end of the stirring shaft (101).

4. The extraction apparatus for fecal microbiota transplantation according to claim 1, characterized in that: The driving assembly further includes a driven shaft (204), a driven wheel (205) and a transmission belt (206), the lower end of the rotating shaft (4) is provided with a driven shaft (204), the sidewall of the driven shaft (204) is provided with a driven wheel (205), the outside of the driving wheel (203) is provided with a transmission belt (206), the driving wheel (203) is rotatably connected with the transmission belt (206), and the driven wheel (205) is arranged in the inside of the transmission belt (206) and rotatably connected with the transmission belt (206).

5. The extraction device for fecal microbiota transplantation according to claim 1, characterized in that: The side of the stirring tank (3) is provided with a main material pipe (301), and the other side of the stirring tank (3) is provided with an auxiliary material pipe (302).

6. The extraction device for fecal microbiota transplantation according to claim 1, characterized in that: The feeding assembly includes a feeding pipe (401) and a feeding valve (402), the upper side of the separation tank (6) is provided with a feeding pipe (401), the sidewall of the feeding pipe (401) is provided with a feeding valve (402), the upper end of the feeding pipe (401) is arranged on the bottom wall of the stirring tank (3), and the other end of the feeding pipe (401) is arranged above the separation cylinder (7).

7. The extraction device for fecal microbiota transplantation according to claim 1, characterized in that: The discharge assembly includes a discharge pipe (501), a discharge valve (502) and a collection tank (503), the bottom side of the separation tank (6) is provided with a discharge pipe (501), the sidewall of the discharge pipe (501) is provided with a discharge valve (502), and one side of the frame (1) is provided with a collection tank (503).