Desktop cell culture sterile operation table
By designing a desktop cell culture aseptic operating table, which utilizes high-pressure clean air to form an air wall and an adjustable outer shell structure, the problem of the destruction of the aseptic environment during the operation of the culture dish is solved, realizing convenient aseptic operation and constant temperature environment, and adapting to different operating habits.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-03-20
- Publication Date
- 2026-03-03
AI Technical Summary
In the prior art, the sterile environment is easily disrupted when the culture dish is removed from the culture instrument during cell culture, which can interfere with the culture results.
A desktop cell culture sterile operating table was designed, including a support and a carrier. The carrier has an inner and outer shell structure. The bottom of the inner shell has air holes. The outer shell provides high-pressure clean air to form an air wall. The top plate cooperates with the inner shell to isolate the external air. The connecting arm can adjust the position of the outer shell. The built-in ultraviolet lamp and heating wire ensure clean airflow and constant temperature.
The operating table creates a relatively sterile environment, protects the sterility of the culture dishes, facilitates the handling of culture dishes by operators, adapts to different operating habits, and improves the convenience of operation and the airtightness of the sterile environment.
Smart Images
Figure CN223963508U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the technical field of cell culture equipment, specifically a desktop cell culture sterile operating table. Background Technology
[0002] Cell culture is a method of simulating the in vivo environment (sterility, suitable temperature, pH, and certain nutritional conditions) to enable cells to survive, grow, reproduce, and maintain their main structures and functions. It is a common technique in biology. Current technologies generally use large-scale cell culture instruments. Although these instruments provide a sterile environment, there are still opportunities for microbial contamination during actual operation, which can disrupt the sterile environment of the culture dish and interfere with the culture results.
[0003] During cell culture, various processing operations are required on the culture dishes, such as adding culture medium. At this time, the culture dishes need to be removed from the culture instrument and placed on a regular workbench for processing. Although this process is brief, it still disrupts the sterile environment inside the culture dish. Utility Model Content
[0004] The present invention aims to at least partially solve one of the technical problems in the related art: to provide a desktop cell culture sterile operating table that can be portablely placed on various work surfaces to create a temporary sterile environment, so that culture vessels containing cells can be placed in this sterile environment, while facilitating the operation of the culture vessels by the operator.
[0005] Therefore, one objective of this utility model is to provide a desktop aseptic operating table for cell culture, comprising a support and a carrier mounted on the support. The carrier includes an outer shell connected to the support, and an inner shell with an upward-facing opening at the top of the outer shell. The inner shell is rotatably fitted with the outer shell. The inner shell has a functional area for placing culture vessels at its horizontal center, and a plurality of air holes arranged around the functional area at the bottom of the inner shell, each air hole facing outwards to form an air wall around the functional area. The outer shell is equipped with an air supply device for providing high-pressure clean air to each air hole. The airflow generated by the air holes forms an air wall around the functional area, thereby isolating the culture vessels placed within the functional area of the inner shell from the air in the external environment, creating a relatively sterile environment.
[0006] According to one example of this utility model, a top plate is provided above the inner shell, and a gap is left between the top plate and the opening of the inner shell for placing and removing culture vessels. The top plate, suspended above the inner shell, works in conjunction with the air wall blown out by the vents to cover the entire functional area, isolating the convection of internal and external air and maintaining a sterile environment within the functional area.
[0007] According to one example of this utility model, the outer shell and the support are connected by a connecting arm. The connecting arm is configured to allow the relative position between the outer shell and the support to be adjustable, so that the top plate covers the opening of the inner shell or is positioned away from the opening of the inner shell, forming a gap for placing and removing culture vessels. The top plate has an air vent. The relative position between the outer shell and the top plate can be adjusted by the connecting arm. When no processing operation is required for the culture vessels, the outer shell can be moved so that the top plate covers the opening of the inner shell, improving the effect of isolating external air. When processing operation is required for the culture vessels, the position of the outer shell can be adjusted so that the width of the gap between the outer shell and the top plate is adjustable, adapting to the operating habits of different operators.
[0008] According to one example of this utility model, connecting arms are symmetrically arranged on both sides of the outer shell. Each connecting arm consists of multiple hinged arms. Any two adjacent arms are hinged to each other. The upper end of the first arm is hinged to the support, and the lower end of the last arm is hinged to the outer shell. Friction dampers are provided between any two adjacent arms, between the first arm and the support, and between the last arm and the outer shell. The friction dampers are designed to maintain the outer shell in its current position after the external force driving its movement is eliminated. The use of multi-section hinged connecting arms allows the outer shell to be adjusted not only vertically but also forward and backward, bringing it closer to the operator and making it more convenient for handling culture vessels.
[0009] According to one example of the present invention, the top plate has an annular interface that matches the opening position of the inner shell, and the air outlet is arranged on the side wall of the annular interface.
[0010] According to an example of the present invention, the inner shell and the inner sidewall of the outer shell together form an equipment mounting cavity. The air supply device includes a fan installed in the equipment mounting cavity and a motor for driving the fan. The outer shell is provided with an air inlet communicating with the equipment mounting cavity. An airflow channel communicating with the air inlet and the air hole is formed in the equipment mounting cavity. The fan is arranged in the airflow channel.
[0011] According to one example of this invention, the device mounting cavity is equipped with an ultraviolet lamp for providing ultraviolet light and heating wires for heating air, which are arranged sequentially along the airflow direction within the airflow channel. The ultraviolet lamp can sterilize the air drawn in through the air inlet, and the heating wires can heat the sterilized air, thereby changing the temperature of the environment surrounding the culture dish and enabling the culture dish to complete cell culture at a suitable temperature.
[0012] The above technical solution has the following advantages or beneficial effects: First, the carrier can be placed arbitrarily on existing workbenches along with the support, facilitating handling and use. Second, the air holes on the outer shell surrounding the functional area can blow air outward to form an air wall around the functional area, isolating the environment of the functional area from the external environment, thereby creating a relatively sterile environment for the culture vessels within the functional area. Third, the outer shell is connected to the support via connecting arms, allowing for height adjustment. When culture vessels need to be processed, the operator can move the outer shell up or down, ensuring the spacing in the middle suits the operator's operating habits. When handling culture vessels, the outer shell can be driven upwards until the top plate closes onto the opening of the inner shell, thereby isolating the space inside the inner shell from the top plate, improving airtightness, and the vents continuously inflate inwards, creating a positive pressure sterile environment. Secondly, the outer shell is connected to the support via a multi-section connecting arm, so the outer shell can be adjusted not only vertically but also horizontally. The operator can move the outer shell forward to the position where the operator stands, making it easier for the operator to handle the culture vessels inside the inner shell. Finally, the built-in ultraviolet lamp and heating wire ensure that the air blown out of the vents is constant-temperature clean air.
[0013] Additional aspects and advantages of this invention will be set forth in part in the description which follows, and in part will be obvious from the description, or may be learned by practice of the invention. Attached Figure Description
[0014] Figure 1 This is an axonometric view of the desktop cell culture sterile operating table of this utility model in the closed state.
[0015] Figure 2 for Figure 1 A front view of the aseptic workbench for cell culture on the central desktop.
[0016] Figure 3 for Figure 1 A top view of the aseptic workbench for cell culture.
[0017] Figure 4 for Figure 3 A cross-sectional view along the "AA" direction.
[0018] Figure 5 for Figure 4 A magnified view of a portion of region "B".
[0019] Figure 6 for Figure 1 Axial view of the desktop cell culture sterile operating table in the open state.
[0020] Among them, 100 is the support frame; 200 is the carrier; and 300 is the platform.
[0021] 1. Upright pole; 2. Support leg; 3. Horizontal bar; 4. Outer shell; 5. Inner shell; 5.1 Functional area; 6. Air vent; 7. Equipment mounting cavity; 8. Motor; 9. Fan; 10. Ultraviolet lamp; 11. Heating wire; 12. Air inlet; 13. Culture vessel; 14. Top plate; 15. Annular interface; 16. Air outlet; 17. Connecting arm; 17.1 Support arm. Detailed Implementation
[0022] The embodiments of this utility model are described in detail below. Examples of these embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals denote the same or similar elements or elements having the same or similar functions throughout. The embodiments described below with reference to the accompanying drawings are exemplary and intended to explain this utility model, and should not be construed as limiting this utility model.
[0023] The desktop cell culture sterile operating table according to an embodiment of the present invention will now be described in detail with reference to the accompanying drawings.
[0024] This utility model provides a desktop aseptic operating table for cell culture, as shown in the figure. It includes a support and a carrier mounted on the support. The carrier includes an outer shell 4 connected to the support. The outer shell 4 has a cylindrical structure. The top of the outer shell 4 has an inner shell 5 with its opening facing upwards. The inner shell 5 is coaxially arranged with the outer shell 4 and rotatably fitted. The inner shell 5 has a bowl-shaped structure with its opening facing upwards. The interior of the inner shell 5 has a functional area 5.1 for placing culture vessels 13 at the middle position along the horizontal direction. The bottom of the inner shell 5 has a plurality of air holes 6 arranged around the functional area 5.1. Each air hole 6 is configured to face outwards from the inner shell 5 to form an air wall around the functional area 5.1. The outer shell 4 is provided with an air supply device for providing high-pressure clean air to each air hole 6. The above-mentioned configuration of each air hole 6 facing outwards from the inner shell 5 means that the air hole 6 faces the opening from bottom to top.
[0025] In this embodiment, after the air supply device is powered on, it can continuously provide clean compressed air. After the compressed air is ejected through the air hole 6, it can form an annular air wall, thereby isolating the space where the functional area 5.1 is located from the external environment. As the airflow in the air hole continues to be ejected, the original air in the functional area 5.1 will also be carried away from the functional area 5.1 by the air flowing inside the air wall. Some of the clean air ejected from the air hole will replenish the functional area 5.1, ultimately making the functional area 5.1 a sterile clean environment compared to the external environment.
[0026] In the above embodiments, the operator is generally located on one side of the carrier. When the operator operates the multiple culture vessels 13 inside the inner shell 5, it is more convenient to operate the culture vessels 13 closer to the operator, while it is more inconvenient to operate the culture vessels 13 farther away from the operator. Through the rotational cooperation between the inner shell 5 and the outer shell 4, the culture vessels 13 inside the inner shell 5 that are far away from the operator's position can be moved to a position closer to the operator simply by rotating the inner shell 5.
[0027] Based on one of the preferred examples of pores in the above embodiments:
[0028] The air vents are arranged upwards along the axial direction of the inner shell 5. The air wall formed by the high-speed airflow ejected from all the air vents is annular. However, there are still areas directly above the inner shell 5 that cannot be covered by the air wall. Therefore, as follows: Figure 5 As shown, a top plate 14 is provided above the inner shell 5, and a gap is left between the top plate 14 and the opening of the inner shell 5 for placing and removing the culture vessel 13. The gap between the top plate 14 and the opening of the inner shell 5 serves as a working channel for the operator to operate the culture vessel 13 inside the inner shell 5. In this embodiment, the top of the annular air wall formed by the vents is aligned with the top plate 14, so that the top plate 14, the air wall and the inner shell 5 can enclose a sterile space, isolating it from the air in the external environment.
[0029] A second preferred example of pores based on the above embodiments:
[0030] like Figure 5 As shown, the air vents at the bottom of the inner cavity of the inner shell 5 are designed to be vertically upward and horizontally inclined towards the center of the inner shell 5. This allows the airflow from the circumferentially arranged air vents to form a conical air wall outside the functional area 5.1. This conical air wall covers the functional area 5.1, thereby effectively preventing air from the external environment from convection with the air inside the functional area 5.1, creating a sterile environment.
[0031] In the above embodiment, a larger gap between the top plate 14 and the opening of the inner shell 5 makes it easier for the operator to handle the various culture vessels 13 placed inside the inner shell 5. However, an excessively large gap will reduce the isolation effect of the air wall blown out by the vent, affecting the aseptic isolation effect. Conversely, a smaller gap between the top plate 14 and the opening of the inner shell 5 is more conducive to maintaining a sterile environment inside the inner shell 5. However, an excessively small gap will cause inconvenience to the operator. Therefore, the improvement of this embodiment is that the outer shell 4 and the support are connected by a connecting arm 17. The connecting arm 17 is configured to allow the relative position between the outer shell 4 and the support to be adjustable, so that the outer shell 4 has a closed state that covers the opening of the inner shell 5, and an open state that is away from the opening of the inner shell 5 and forms a gap for picking up and placing the culture vessels 13. Figure 1-5The outer shell 4 is in the closed state, in which Figure 6 The outer shell 4 is in the open state. In this embodiment, when the operator does not need to handle the culture dish 13, the outer shell 4 can be pushed to move the outer shell 4 to the open state. Figure 6 In the closed state shown, the top plate 14 completely covers the opening of the inner shell 5, maintaining positive pressure inside the inner shell 5 and completely preventing air from the external environment from entering. When the operator needs to handle the culture vessel 13 inside the inner shell 5, they only need to pull the outer shell 4 to leave a sufficient distance between the outer shell 4 and the top plate 14 for the operator to operate. This distance can be adjusted according to the needs of different operators, at which point the outer shell 4 is in the open state.
[0032] Preferably, the top plate 14 has an air outlet 16 for connecting the inner cavity formed by the top plate 14 and the inner shell 5. Specifically, the air outlet 16 is provided with a filter screen, so that when the outer shell 4 is in the closed state, as the air supply device continuously fills the inner cavity of the inner shell 5 with air, excess air can flow out from the air outlet 16, ensuring positive pressure in the inner cavity of the inner shell 5 and maintaining a sterile environment.
[0033] Furthermore, such as Figure 5 As shown, the top plate 14 has an annular interface 15 that matches the opening position of the inner shell 5. The annular interface 15 is an annular cylindrical structure. The upper end of the annular interface 15 is fixed to the lower end face of the top plate 14, and the lower end of the annular interface 15 matches the opening position of the inner shell 5. The air outlet 16 is arranged on the side wall of the annular interface 15. Preferably, there are multiple air outlets 16, which are evenly arranged circumferentially on the side wall of the annular interface 15.
[0034] Based on the preferred embodiment of the connecting arm 17 in the above embodiments:
[0035] like Figure 5 and Figure 6 As shown, connecting arms 17 are symmetrically arranged on both sides of the outer shell 4. The connecting arms 17 are composed of multiple hinged arms 17.1. Any two adjacent arms 17.1 are hinged to each other. The upper end of the first arm 17.1 is hinged to the bracket, and the lower end of the last arm 17.1 is hinged to the outer shell 4. Friction dampers are provided between any two adjacent arms 17.1, between the first arm 17.1 and the bracket, and between the last arm 17.1 and the outer shell 4. The friction dampers are configured to keep the outer shell 4 in its current position after the external force driving the outer shell 4 to move is eliminated.
[0036] Preferably, the connecting arm 17 includes three support arms 17.1. The upper end of the first support arm 17.1 is hinged to a convex shaft on the bracket, the upper end of the second support arm 17.1 is hinged to the lower end of the first support arm 17.1, the upper end of the last support arm 17.1 is hinged to the lower end of the second support arm 17.1, and the lower end of the last support arm 17.1 is hinged to a convex shaft on the outer wall of the outer shell 4. The hinge in this embodiment is also called a pivot connection. Each hinge is provided with a friction damper. Therefore, when the outer shell 4 is subjected to an external force, it can overcome the frictional resistance of each friction damper and move. When the external force is removed, the frictional resistance provided by each friction damper allows the outer shell 4 to overcome its own gravity and remain in its current position.
[0037] It should be understood that the friction damper is a commercially available product in the industry. In this embodiment, it has been shown that, under the premise that the pivot connection can be rotated to any position and then maintained at the current position, it is simple to install various friction dampers according to the existing technology. Therefore, the structure and installation relationship of this friction damper will not be described in detail in this embodiment.
[0038] Based on the preferred gas supply equipment in the above embodiments, such as Figure 5 As shown, the housing 4 has an internal equipment mounting cavity 7. The air supply device includes a fan 9 installed in the equipment mounting cavity 7 and a motor 8 for driving the fan 9. The side wall of the housing 4 is provided with an air inlet 12 that communicates with the equipment mounting cavity 7. The equipment mounting cavity 7 is provided with several partitions, each partition dividing the inner cavity of the equipment mounting cavity 7 into an airflow channel and a motor cavity for accommodating the motor 8. The motor 8 is fixed in the motor cavity. The fan 9 is arranged in the airflow channel, and the output shaft of the motor 8 passes through the motor cavity and is connected to the fan 9 in the airflow channel for driving the fan 9. The two ends of the airflow channel are respectively connected to the air inlet 12 and the air hole 6. The fan 9 drives the air in the airflow channel to flow towards the location of the air hole 6.
[0039] Specifically, the equipment mounting cavity 7 includes a fan cavity and an intermediate cavity located between the fan cavity and the inner shell. Multiple annular baffles are arranged radially outward within the intermediate cavity, dividing it into an S-shaped channel. The center of the fan cavity is connected to the center of the intermediate cavity via a central hole. The motor cavity is located in the center of the intermediate cavity, and the motor 8 is located within the motor cavity. The output shaft of the motor 8 passes vertically through the central hole and is connected to the fan 9 within the fan cavity. The proximal end of the S-shaped channel is connected to the fan cavity via the central hole, and the distal end is connected to the air vents. The equipment mounting cavity 7 contains an ultraviolet lamp 10 for providing ultraviolet light and a heating wire 11 for heating the air. The ultraviolet lamp 10 and the heating wire 11 are arranged sequentially along the airflow direction within the S-shaped channel. The ultraviolet lamp should be positioned away from the air vents to prevent some of the ultraviolet light generated by the lamp from escaping through the air vents.
[0040] Furthermore, the housing is provided with a power source for providing electrical energy to the heating wire 11 and the motor 8. This power source can be a battery or a power cord for electrically connecting to an external power source.
[0041] Preferably, a filter screen is provided on the air inlet 12 or in the airflow channel to filter the air drawn into the airflow channel, so that the air blown out from the air hole is clean air at a constant temperature.
[0042] Based on the preferred embodiments described above, such as Figure 5 and Figure 6 As shown, the culture vessel 13 for cell culture includes bottle-shaped culture flasks and plate-shaped culture dishes.
[0043] Preferably, the inner shell 5 is provided with a shelf (not shown in the figure), which consists of two plates hinged together. A friction damper is provided between the two plates to increase frictional resistance. By swinging the two plates, the angle between the two plates can be adjusted. One plate of the shelf is placed in the inner shell and fits against the bottom of the groove of the inner shell, while the other plate is tilted. The culture vessel 13 is placed on the tilted plate, so that the culture vessel 13 can be placed in the inner shell 5 in an inclined manner.
[0044] Improvements based on the above embodiments: such as Figure 1-4 As shown, the support includes two spaced-apart uprights 1, with supporting feet 2 at their lower ends. A crossbar 3 is positioned between the two uprights 1, with both ends of the crossbar 3 fixed to the upper ends of the two uprights 1 respectively. The upper end of the connecting arm is connected to the crossbar 3. Specifically, the upper end of the first support arm 17.1 is hinged to a convex shaft on the crossbar 3.
[0045] The upright 1 is a telescopic rod capable of extending and retracting along its own length. This telescopic rod includes, but is not limited to, an electric actuator.
[0046] In the above embodiments, the upright 1 and the crossbar 3 are supported by lightweight metal or plastic materials, which makes it convenient for the entire desktop cell culture sterile operating table to be placed on various platforms 300.
[0047] Although embodiments of the present invention have been shown and described above, it is understood that the above embodiments are exemplary and should not be construed as limiting the present invention. Those skilled in the art can make changes, modifications, substitutions and variations to the above embodiments within the scope of the present invention.
[0048] For those skilled in the art, various changes and modifications will undoubtedly be apparent after reading the above description. Therefore, the appended claims should be considered as covering all changes and modifications that encompass the true intent and scope of this utility model. Any and all equivalent scope and content within the scope of the claims should be considered as still falling within the intent and scope of this utility model.
Claims
1. A desktop sterile operating table for cell culture, comprising a support and a carrier disposed on the support, characterized in that: The carrier includes an outer shell (4) connected to a support. The top of the outer shell (4) is provided with an inner shell (5) with the opening facing upward. The inner shell (5) is rotatably engaged with the outer shell (4). The inner shell (5) has a functional area (5.1) for placing a culture vessel (13) at the middle position along the horizontal direction. The bottom of the inner shell (5) is provided with a number of air holes (6) arranged around the functional area (5.1). Each air hole (6) is set to face outward from the inner shell (5) to form an air wall around the functional area (5.1). The outer shell (4) is provided with an air supply device for providing high-pressure clean air to each air hole (6).
2. The desktop cell culture sterile operating table according to claim 1, characterized in that: The inner shell (5) is provided with a top plate (14) above it, and a gap is left between the top plate (14) and the opening of the inner shell (5) for taking out and putting in the culture vessel (13).
3. The desktop cell culture sterile operating table according to claim 2, characterized in that: The outer shell (4) is connected to the support via a connecting arm (17), which is configured to allow the relative position between the outer shell (4) and the support to be adjustable so that the top plate (14) covers the opening of the inner shell (5) or is located away from the opening of the inner shell (5) and forms a gap for taking out and placing the culture vessel (13). The top plate (14) has an air outlet (16).
4. The desktop cell culture sterile operating table according to claim 3, characterized in that: The outer shell (4) is symmetrically provided with connecting arms (17) on both sides. The connecting arms (17) are composed of multiple hinged arms (17.1). Any two adjacent arms (17.1) are hinged to each other. The upper end of the first arm (17.1) is hinged to the bracket, and the lower end of the last arm (17.1) is hinged to the outer shell (4). Friction dampers are provided between any two adjacent arms (17.1), between the first arm (17.1) and the bracket, and between the last arm (17.1) and the outer shell (4).
5. The desktop cell culture sterile operating table according to claim 3, characterized in that: The top plate (14) has an annular interface (15) that matches the opening position of the inner shell (5), and the air outlet (16) is arranged on the side wall of the annular interface (15).
6. The desktop cell culture sterile operating table according to any one of claims 1-5, characterized in that: The inner shell (5) and the inner sidewall of the outer shell (4) together form an equipment mounting cavity (7). The air supply device includes a fan (9) installed in the equipment mounting cavity (7) and a motor (8) for driving the fan (9). The outer shell (4) is provided with an air inlet (12) that communicates with the equipment mounting cavity (7). An airflow channel is formed in the equipment mounting cavity (7) that communicates with the air inlet (12) and the air hole (6). The fan (9) is arranged in the airflow channel.
7. The desktop cell culture sterile operating table according to claim 6, characterized in that: The device mounting cavity (7) is equipped with an ultraviolet lamp (10) for providing ultraviolet light and a heating wire (11) for heating air. The ultraviolet lamp (10) and the heating wire (11) are arranged sequentially along the airflow direction in the airflow channel.