Animal serum sample separating and collecting device

Abstract

The utility model belongs to the technical field of animal serum sample collection, and discloses an animal serum sample separation and collection device which comprises a blood collector, the supporting frame comprises a rectangular bottom plate and four supporting columns, the four supporting columns are perpendicularly and fixedly arranged at the four corners of the upper surface of the bottom plate respectively to define a rectangular frame structure, and a plurality of push rods matched with through holes in the bottom end of a needle cylinder of the blood collector are perpendicularly arranged on the upper surface of the bottom plate; the pressing support is located above the bottom plate and can be in sliding connection in the axial direction of the four supporting columns; two second transverse rods of the downward pressing support are arranged on the two opposite sides of the rectangular frame structure respectively, a plurality of second supporting rods stretch across the two second transverse rods, a gland is arranged in the middle of each second supporting rod, and a through hole allowing the connecting part to penetrate is formed in the center of each gland in a penetrating mode; and the push rods are in one-to-one correspondence with the glands, and the push rods coincide with the central axes of the through holes of the corresponding glands. The serum separating and collecting device can separate and collect serum in batches, improves efficiency, reduces workload and is high in practicability.

Description

Technical Field

[0001] This utility model belongs to the field of animal serum sample collection technology, and more specifically, this utility model relates to an animal serum sample separation and collection device. Background Technology

[0002] Animal serum testing is a commonly used auxiliary examination method in animal field epidemiological investigations, enabling the detection of biochemical, immunological, and hormonal aspects through serum. Currently, when extracting animal serum, for example, in a farm with over 100 pigs, technicians need to randomly collect blood samples from dozens of pigs to obtain a batch of blood samples (one syringe per pig). The batch of blood samples is then transported to the laboratory and centrifuged to separate the samples into layers. The upper serum layer is then extracted tube by tube. Because current technology requires the use of syringes to draw blood from animals, transferring the extracted blood samples to test tubes for sealing, transporting the test tubes to the laboratory centrifuge for extraction, and then aspirating or pouring the separated serum from the test tubes into EP tubes for testing, the transfer of multiple containers and equipment (each syringe, each test tube, each aspiration device) for the batch of blood samples is cumbersome.

[0003] In response, existing technology discloses an animal disease serum sampling device (publication number CN221511900U), which features a detachable connection at the top of the sampling tube. A support frame is threaded onto the outer wall of the sampling tube, and air cylinders are mounted on the support frame on both sides of the sampling tube. Each air cylinder contains a gas piston elastically connected to it, and the gas piston is connected to a drive assembly. A transfer tube is connected to the bottom of both air cylinders, and the transfer tube and sampling tube are coaxially aligned and connected to the bottom of the sampling tube. While this existing animal disease serum sampling device can complete blood collection, centrifugation, and serum extraction all within the sampling tube, solving the problem of cumbersome transfer operations between multiple containers, it requires complex modifications to the needle structure. The blood collection, centrifugation, and serum collection processes all require air cylinders to be installed on both sides of each sampling tube, and the air cylinders are difficult to disassemble. Furthermore, separating and collecting serum from batches of sampling tubes one by one is tedious and inconvenient, making it unsuitable for batch processing.

[0004] Regarding the complex structure of modified needles, existing technologies have developed blood collection devices specifically for veterinary blood collection (such as...). Figure 6As shown), it includes a syringe 24, a piston 23, a core rod 28, and a needle 29. The piston 23 is slidably and sealingly disposed inside the syringe 24. A central groove at the bottom of the piston 23 is detachably connected to one end of the core rod 28. The other end of the core rod 28 passes through a through hole at the bottom of the syringe 24. A connecting part at the top of the syringe 24 is detachably connected to the needle 29. Graduation lines are provided on the side wall of the syringe 24. Although this blood collection device has a simple structure, the syringe 24, after disassembling the needle and core rod, can be easily placed on a storage rack and transported to the laboratory, and can be directly placed in a centrifuge for centrifugation without transferring it to test tubes, solving the problem of cumbersome transfer operations of multiple container devices (such as...). Figure 7 , Figure 8 , Figure 9 (The image shows a photograph of the existing technology in operation). However, currently, collecting serum using this blood collection device still requires manual pouring of a specified amount of serum into the EP tube one by one. It is evident that the current technology for collecting animal serum samples relies heavily on the skilled technicians' ability to control the stability of the pouring, the tilt position, and the amount poured. Moreover, opening the sampling cap at the top of the syringe makes it easy to spill the serum, and the amount poured is difficult to control, resulting in low efficiency and a large workload, which urgently needs improvement. Utility Model Content

[0005] One object of this invention is to solve at least the aforementioned defects and to provide at least the advantages described below.

[0006] This invention provides an animal serum sample separation and collection device. It supports a batch of syringes after centrifugation and stratification by setting a support frame, and squeezes the batch of syringes along the syringe axis by pressing down the support. It can realize that blood collection, centrifugation and serum collection can all be completed in the syringe of the blood collector. It has a simple structure, can collect serum in batches, improve efficiency, reduce workload and has strong practicality.

[0007] This utility model provides an animal serum sample separation and collection device, which includes a blood collection device, wherein the top of the syringe of the blood collection device is provided with a connecting part that passes through the top of the syringe, and further includes:

[0008] The support frame includes a rectangular base plate and four pillars. The four pillars are respectively vertically fixed at the four corners of the upper surface of the base plate, so that the four pillars form a rectangular frame structure on the base plate. The upper surface of the base plate is vertically provided with a plurality of push rods adapted to the through holes at the bottom end of the syringe of the blood collection device. The push rods are used to pass through the through holes at the bottom end of the syringe and the upper end face of the push rods presses against the central groove at the bottom of the piston inside the syringe.

[0009] A pressure bracket, located above the base plate, is slidably connected along the axial direction of the four pillars. The pressure bracket includes two second crossbars, multiple pressure caps, and multiple second support rods. The two second crossbars are respectively positioned on opposite sides of the rectangular frame structure. The multiple second support rods are parallel to each other and span across the two second crossbars in the same plane. Each second support rod has one or two pressure caps in its center. Each pressure cap has a through hole in its center. The diameter of the through hole is larger than the outer diameter of the syringe tip connection and smaller than the inner diameter of the syringe. The through hole allows the syringe tip connection directly below the pressure cap to pass through. Each push rod corresponds one-to-one with each pressure cap, and the central axis of the push rod coincides with the central axis of the through hole of the corresponding pressure cap.

[0010] The connecting part connects to the needle during blood collection and to the guide tube during serum collection.

[0011] Preferably, the downward support can be slidably connected along the axial direction of the four pillars as follows: the two second crossbars are parallel to each other and their planes are parallel to the base plate, and square second sliders are fixed at both ends of each second crossbar. Second sliding grooves matching the second sliders are provided on the opposite sides of the two pillars on the corresponding sides of the rectangular frame structure.

[0012] Preferably, it also includes a drive mechanism for driving the lower support to slide along the axial direction of the four pillars. The drive mechanism includes a ball screw and a stepper motor. The ball screw is arranged in the second slide groove along the axial direction of the pillar. One end of the ball screw is rotatably connected to the upper wall of the second slide groove through a bearing, and the other end is connected to the output end of the stepper motor. The second slider is fixedly connected to the nut of the ball screw.

[0013] Preferably, the through hole of the cap is a tapered through hole that is larger at the bottom and smaller at the top. The inner diameter of the upper opening of the tapered through hole is equal to or slightly larger than the outer diameter of the root of the syringe tip connector, and the inner diameter of the lower opening of the tapered through hole is equal to or slightly larger than the inner diameter of the syringe.

[0014] Preferably, it also includes a positioning bracket, which is located between the pressing bracket and the base plate and can be slidably connected along the axial direction of the four pillars. The positioning bracket, the pressing bracket, and the base plate are parallel to each other. The positioning bracket includes two first crossbars, multiple spacers, and a first support rod. The two first crossbars are respectively arranged on the other opposite sides of the rectangular frame structure. The first support rod spans between the two first crossbars. The multiple spacers are equally spaced and vertically arranged on one or both sides of the first support rod. The multiple spacers are parallel to each other and are on the same plane as the first support rod and the first crossbar. The distance between two adjacent spacers is equal to or slightly greater than the outer diameter of the syringe. The rectangular space between two adjacent spacers corresponds one-to-one with each of the caps. The rectangular midline of the rectangular space intersects perpendicularly with the central axis of the corresponding cap through hole. The rectangular midline is parallel to the spacer.

[0015] Preferably, the positioning bracket can be slidably connected along the axial direction of the four pillars as follows: the two first crossbars are parallel to each other and the plane of the same plane is parallel to the base plate, and square first sliders are fixed at both ends of each first crossbar. First grooves matching the first sliders are opened on the opposite sides of the two pillars on the corresponding sides of the rectangular frame structure. A locking mechanism for clamping and releasing the first sliders is provided on the pillars with the first grooves.

[0016] Preferably, the system also includes a contact-type limit sensor and a controller. The contact-type limit sensor is disposed on the upper surface of the first support rod of the positioning bracket and located directly below the second support rod. The contact-type limit sensor and the stepper motor are electrically connected to the controller.

[0017] Preferably, the locking mechanism includes multiple limiting holes and multiple limiting bolts. The multiple limiting holes are arranged sequentially along the axial direction of the support column of the first slide groove. The multiple limiting holes all penetrate the side wall of the first slide groove. The multiple limiting bolts are screwed to the multiple limiting holes and can pass through the side wall of the first slide groove to press against the first slider.

[0018] Preferably, the two second crossbars are located on the long side borders of the rectangular frame structure, and the two first crossbars are located on the wide side borders of the rectangular frame structure.

[0019] Preferably, the multiple caps and multiple spacers are made of transparent material, with a conspicuous edge line on the lower edge of the caps and a conspicuous edge line on the upper edge of the spacers.

[0020] This utility model has at least the following beneficial effects:

[0021] Firstly, this utility model supports the batch of syringes after centrifugation and stratification by setting a support frame, and squeezes the batch of syringes along the syringe axis by pressing down the support bracket. This allows blood collection, centrifugation and serum collection to be completed inside the syringe of the blood collector. The structure is simple, and it can collect serum in batches, improving efficiency, reducing workload and making it highly practical.

[0022] Secondly, this invention, through the design of a positioning bracket, not only provides guidance but also limits the distance the downward-pressing bracket moves towards the syringe, controlling the extrusion volume and enabling batch quantitative collection. It can also meet the needs of collecting multiple tests and effectively improve the efficiency of serum separation and collection.

[0023] Furthermore, this invention features prominent edge lines on the lower edge of the cap and the upper edge of the spacer strip, which facilitates observation, control, and adjustment of batch quantitative collection.

[0024] Other advantages, objectives and features of this invention will be partly apparent from the following description, and partly understood by those skilled in the art through study and practice of this invention. Attached Figure Description

[0025] Figure 1 This is a three-dimensional structural diagram of one implementation of the animal serum sample separation and collection device of this utility model;

[0026] Figure 2 This is a front view of the internal structure of one implementation of the animal serum sample separation and collection device of this utility model, in which a syringe is placed.

[0027] Figure 3 This is a front view of the internal structure of one implementation of the animal serum sample separation and collection device of this utility model;

[0028] Figure 4 This is a top view of the internal structure of one implementation of the animal serum sample separation and collection device of this utility model;

[0029] Figure 5 This is a top view of the internal structure of another implementation of the animal serum sample separation and collection device of this utility model;

[0030] Figure 6 A schematic diagram of the structure of a blood collection device specifically designed for livestock blood collection using existing technology;

[0031] Figure 7 A diagram illustrating blood collection using existing technology;

[0032] Figure 8 A diagram illustrating the centrifugation and stratification of a blood collection device syringe using existing technology;

[0033] Figure 9An illustration of serum being poured downwards from the syringe of a blood collection device, demonstrating the existing technology.

[0034] The components include: base plate 1; limiting hole 3; limiting bolt 4; support column 5; first slide groove 6; first crossbar 7; spacer 8; contact limit sensor 9; first support rod 10; second crossbar 11; second support rod 12; pressure cap 13; through hole 14; second slide groove 15; stepper motor 16; second slider 17; ball screw 18; first slider 19; connecting part 20; serum 21; blood clot or blood cell sediment 22; piston 23; syringe 24; push rod 25; downward support 26; positioning support 27; core rod 28; and needle 29. Detailed Implementation

[0035] The present invention will be further described in detail below with reference to the embodiments, so that those skilled in the art can implement it based on the description.

[0036] It should be noted that, unless otherwise specified, the experimental methods described in the following embodiments are conventional methods, and the reagents and materials described are commercially available. In the description of this utility model, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "setting" should be interpreted broadly. For example, they can refer to fixed connection or setting, detachable connection or setting, or integral connection or setting. Those skilled in the art can understand the specific meaning of the above terms in this utility model based on the specific circumstances. The terms "lateral," "longitudinal," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," and "outer," etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings, and are only for the convenience of describing this utility model and simplifying the description. They do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model.

[0037] Figures 1-4 An implementation of an animal serum sample separation and collection device is shown, which includes:

[0038] The blood collection device has a connecting part 20 that passes through the syringe at the top of the syringe. The connecting part 20 is used to connect the needle 29 during blood collection and to connect the guide tube during serum collection.

[0039] The support frame includes a rectangular base plate 1 and four pillars 5. The four pillars 5 are respectively vertically fixed at the four corners of the upper surface of the base plate 1, so that the four pillars 5 form a rectangular frame structure on the base plate 1. The upper surface of the base plate 1 is vertically provided with a plurality of push rods 25 adapted to the through holes at the bottom end of the syringe 24 of the blood collection device. The push rods 25 are used to pass through the through holes at the bottom end of the syringe 24 and the upper end face of the push rods 25 presses against the central groove at the bottom of the piston 23 inside the syringe 24.

[0040] A pressure bracket 26 is located above the base plate 1 and can be slidably connected along the axial direction of the four pillars 5. The pressure bracket 26 includes two second crossbars 11, multiple pressure caps 13, and multiple second support rods 12. The two second crossbars 11 are respectively arranged on opposite sides of the rectangular frame structure. The multiple second support rods 12 are parallel to each other and span across the two second crossbars 11 in the same plane. Each second support rod 12 has one or two pressure caps 13 in the middle. A through hole 14 is provided in the center of each pressure cap 13. The diameter of the through hole 14 is larger than the outer diameter of the top connecting part 20 of the syringe 24 and smaller than the inner diameter of the syringe 24. The through hole 14 is used for the syringe 24 top connecting part 20 directly below the pressure cap 13 to pass through. Each push rod 25 corresponds to each pressure cap 13, and the central axis of the push rod 25 coincides with the central axis of the through hole 14 of the corresponding pressure cap 13.

[0041] In the above technical solution, the animal serum sample separation and collection device includes a blood collection device, a support frame, and a downward pressure bracket 26. The blood collection device can be an existing animal blood collection device, such as... Figure 6 As shown, the blood collection device includes a syringe 24, a piston 23, a core rod 28, and a needle 29. The piston 23 is slidably and sealingly disposed inside the syringe 24. The central groove at the bottom of the piston 23 is detachably connected to one end of the core rod 28. The other end of the core rod 28 passes through the through hole at the bottom of the syringe 24. There are scale lines on the side wall of the syringe 24. The connecting part 20 at the top of the syringe 24 is a conical or cylindrical structure that is larger at the bottom and smaller at the top, which facilitates the connection of the connecting part 20 with the needle 29 and the guide tube. When collecting blood, the connecting part 20 is connected to the needle 29. When collecting serum, the connecting part is connected to the EP tube through the connecting guide tube.

[0042] The support frame includes a rectangular base plate 1 and four support columns 5. The four support columns 5 are vertically fixed at the four corners of the upper surface of the base plate 1, forming a rectangular frame structure on the base plate 1. Multiple push rods 25, adapted to the bottom through-holes of the syringe 24 of the blood collection device, are vertically arranged on the upper surface of the base plate 1. The push rods 25 are used to pass through the bottom through-holes of the syringe 24, and their upper ends press against the central groove at the bottom of the piston 23 inside the syringe 24. Specifically, the multiple push rods 25 are vertically arranged around the rectangular frame structure formed by the four support columns 5. On the upper surface of the base plate 1 of the frame; during use, the push rod 25 can be inserted into the syringe 24 through the through hole at the bottom of the syringe 24. The upper end face of the push rod 25 can press against the central groove at the bottom of the piston 23 inside the syringe 24. The central axis of the syringe 24 coincides with the central axis of the push rod 25. Applying force to the syringe 24 along the axial direction towards the push rod 25 can push the piston 23 to move a preset displacement, so that the serum in the syringe 24 flows out from the through hole of the syringe 24 connection part 20. The connection part 20 can be connected through the guide tube to realize the batch of serum into batch-labeled EP tubes for subsequent testing.

[0043] A pressure bracket 26 is located above the base plate 1 and can slide along the axial direction of the four support columns 5. The pressure bracket 26 includes two second crossbars 11, multiple pressure caps 13, and multiple second support rods 12. The two second crossbars 11 are respectively arranged on opposite sides of the rectangular frame structure. The multiple second support rods 12 are parallel to each other and span across the two second crossbars 11 in the same plane. Each second support rod 12 has one or two pressure caps 13 in its middle. A through hole 14 is provided in the center of each pressure cap 13. The diameter of the through hole 14 is larger than the outer diameter of the top connecting part 20 of the syringe 24 and smaller than the inner diameter of the syringe 24. The through hole 14 is used for the syringe 24 top connecting part 20 directly below the pressure cap 13 to pass through. Each push rod 25 corresponds one-to-one with each pressure cap 13, and the push rod 25 and The central axis of the through hole 14 corresponding to the pressure cap 13 coincides, so that when the bottom through hole of the blood collection device syringe 24 passes through the push rod 25, and the upper end face of the push rod 25 presses against the central groove at the bottom of the piston 23 inside the syringe 24, the lower pressure bracket 26 is controlled to move closer to the syringe 24 along the axial direction of the four pillars 5. This allows the connecting part 20 at the top of the syringe 24 to pass through the through hole 14 corresponding to the pressure cap 13, and when the lower surface of the pressure cap 13 of the lower pressure bracket 26 abuts against the top of the syringe 24, the lower pressure bracket 26 reaches the set position. Then, the lower pressure bracket 26 is controlled to continue moving towards the syringe 24 along the axial direction of the four pillars 5, applying pressure to the syringe 24 along the axial direction towards the push rod 25, causing the push rod 25 to push the piston 23 to move a preset displacement towards the top of the syringe 24, so that the serum inside the syringe 24 can flow out from the through hole of the connecting part 20 of the syringe 24, realizing separation and collection.

[0044] In use, technicians first collect blood on-site, connecting the connector 20 of the blood collection syringe 24 to the needle 29. After batch blood collection, the syringe 24, after disassembling the needle 29 and the core rod 28, is placed in a centrifuge for batch centrifugation. The blood sample in the syringe 24 is centrifuged and the blood clots or blood cell precipitates 22 coagulate at the bottom of the syringe 24, while the serum 21 is on top. After centrifugation, the lower support 26 is slid upward to a preset height, which is the first preset height for placing the syringe 24 into the support frame. The first preset height is greater than the height of the push rod 25 plus the height of the syringe 24. Then, the batch centrifuged and layered blood collection syringes 24 are removed from the centrifuge. Without removing the sampling end cap at the top of the syringe 24, the batch of syringes 24 are directly inserted into the push rod 25 through the bottom through-hole, and the upper end face of the push rod 25 presses against the central groove at the bottom of the piston 23 inside the syringe 24. Then, the pressure bracket 26 is controlled to move towards the syringe 24 along the axial direction of the four pillars 5, so that the connecting part 20 at the top of the syringe 24 passes through the through hole 14 of the corresponding pressure cap 13, and when the lower surface of the pressure cap 13 of the pressure bracket 26 abuts against the sampling end cap of the syringe 24, the pressure bracket 26 reaches the second set height. The pressure bracket 26 is then kept stationary to provide batch support for the syringe 24. Then, one end of the guide tube is connected to the connecting part 20, and the other end is connected to the corresponding numbered EP tube. Then, according to the serum level position inside the syringe 24, the pressure bracket 26 is controlled to continue moving towards the syringe 24 along the axial direction of the four pillars 5. The device applies pressure to the syringe 24 along the axial direction towards the push rod 25, causing the push rod 25 to push the piston 23 to move a preset displacement towards the top of the syringe 24, so that the serum level in the syringe 24 reaches the guide tube (the guide tube is usually a transparent plastic tube). At this time, the pressure bracket 26 reaches the third preset height (also called the zero position). Then, the pressure bracket 26 is controlled to continue to move a certain distance along the axial direction of the four pillars 5 towards the syringe 24, so that the serum in the syringe 24 can flow out a preset amount of serum through the through hole of the syringe 24 connection part 20 and the guide tube, realizing batch collection and effectively improving the efficiency of serum separation and collection.

[0045] Based on the above implementation, the sliding connection of the pressure support 26 along the axial direction of the four pillars 5 is specifically as follows: the two second crossbars 11 are parallel to each other and their planes are parallel to the base plate 1. Each second crossbar 11 has a square second slider 17 fixed at both ends. On the opposite sides of the two pillars 5 on the corresponding sides of the rectangular frame structure, a second sliding groove 15 matching the second slider 17 is provided. This allows the two second crossbars 11 that are parallel to each other and on the same plane to slide synchronously along the axial direction of the four pillars 5, thereby driving the multiple pressure caps 13 of the pressure support 26 to slide synchronously along the axial direction of the four pillars 5. This enables the control of the multiple pressure caps 13 to move away from, approach, and push the top of the batch syringes 24 inserted on the support frame, thereby realizing the batch separation and collection of serum samples.

[0046] Based on the above implementation, a driving mechanism is also included for driving the lowering bracket 26 to slide axially along the four pillars 5. The driving mechanism includes a ball screw 18 and a stepper motor 16. The ball screw 18 is arranged axially along the pillar 5 in the second slide groove 15. One end of the ball screw 18 is rotatably connected to the upper wall of the second slide groove 15 through a bearing, and the other end is connected to the output end of the stepper motor 16. The second slider 17 is fixedly connected to the nut of the ball screw 18. Depending on the needs, each second slider 17 can be controlled by a corresponding ball screw 18 and a stepper motor 16. Alternatively, one, two, or three of the four second sliders 17 can be controlled by a ball screw 18 and a corresponding stepper motor 16. All of these methods can control the sliding distance of the lowering bracket 26 and are within the protection scope of this invention.

[0047] The upper end of the syringe 24 of the blood collection device is detachably fitted with a sampling end cap. The connecting part 20 is integrally formed with the sampling end cap. The connecting part 20 is used to connect with the needle 29 and the guide tube. For example, during blood collection, the connecting part 20 is connected to the needle 29 to facilitate blood collection; when collecting serum, the connecting part 20 is connected to the guide tube to facilitate the collection of serum into the EP tube. The sampling end cap and the upper end of the syringe 24 are designed to be detachable, which can be easily removed as needed to meet other needs. For example, in the prior art, the serum in the syringe 24 can be poured out by removing the sampling end cap.

[0048] Based on the above implementation, the through hole 14 of the pressure cap 13 is a tapered through hole with a larger bottom and a smaller top. The inner diameter of the upper opening of the tapered through hole is equal to or slightly larger than the outer diameter of the root of the top connecting part 20 of the syringe 24, and the inner diameter of the lower opening of the tapered through hole is equal to or slightly larger than the inner diameter of the syringe 24, so that the tapered through hole can be fitted with the tapered sampling end cap or the tapered top of the syringe 24.

[0049] On the basis of the above implementation, the positioning bracket 27 is located between the pressing bracket 26 and the bottom plate 1 and is slidably connected along the axial direction of the four support columns 5. The positioning bracket 27, the pressing bracket 26 and the bottom plate 1 are parallel to each other. The positioning bracket 27 includes two first cross bars 7, a plurality of spacer bars 8 and first support rods 10. The two first cross bars 7 are respectively arranged on the other two opposite sides of the rectangular frame structure. The first support rods 10 span between the two first cross bars 7. The plurality of spacer bars 8 are respectively arranged at equal intervals and perpendicular to one side or both sides of the first support rod 10. The plurality of spacer bars 8 are parallel to each other and are in the same plane as the first support rod 10 and the first cross bars 7. The distance between adjacent two spacer bars 8 is equal to or slightly larger than the outer diameter of the syringe barrel 24. The rectangular space between adjacent two spacer bars 8 corresponds to each pressing cover 13 one by one. And the rectangular median line of the rectangular space perpendicularly intersects with the central axis of the through hole 14 of the corresponding pressing cover 13. The rectangular median line is parallel to the spacer bar 8. The designed rectangular space formed by adjacent two spacer bars 8 and the first support rod 10 has an opening on one side, which is beneficial for the syringe barrel 24 to be placed at the position corresponding to the push rod 25 and the pressing cover 13 one by one. The design of the positioning bracket 27 not only has a guiding function, but also can limit the moving distance of the pressing bracket 26 towards the syringe barrel 24, control the extrusion amount, realize batch quantitative collection, and can also meet the detection requirements of multiple items, effectively improving the efficiency of collecting serum. For the convenience of showing a single structure, Figures 1-4 The rectangular space between adjacent two spacer bars 8 shown is such that one pressing cover 13 and one push rod 25 are correspondingly shown for every other rectangular space. The structure shown in this view can also achieve the batch collection effect, but the number of batch collection positions is relatively small. As Figure 5 One implementation form shown is that the rectangular space between adjacent two spacer bars 8 corresponds to each pressing cover 13 one by one, and is arranged on both sides of the first support rod 10, increasing the number of batch collection positions and further improving the batch separation and collection effect.

[0050] Based on the above implementation, the positioning bracket 27 can be slidably connected along the axial direction of the four pillars 5 as follows: the two first crossbars 7 are parallel to each other and their planes are parallel to the base plate 1. A square first slider 19 is fixed at both ends of each first crossbar 7. A first groove 6 matching the first slider 19 is opened on the opposite sides of the two pillars 5 on the corresponding sides of the rectangular frame structure. A locking mechanism for clamping and releasing the first slider 19 is provided on the pillar 5 with the first groove 6. The locking mechanism is used to lock and unlock the positioning bracket 27. When the locking mechanism clamps the first slider 19, the positioning bracket 27 can be locked in a pre-set position. Assuming the position does not slide, when the locking mechanism releases the first slider 19, the positioning bracket 27 can slide along the axial direction of the support column 5, realizing the height adjustment of the positioning bracket 27 as needed; in this design, the two first crossbars 7 that are parallel to each other and on the same plane slide synchronously along the axial direction of the four support columns 5, thereby driving multiple rectangular spaces of the positioning bracket 27 to slide synchronously along the axial direction of the four support columns 5. By locking the positioning bracket 27 at a preset height, it is beneficial to control the displacement of the pressing bracket 26 from the zero position to the syringe 24, which is beneficial to control the extrusion volume, and realize the batch quantitative separation and collection of serum samples in the batch syringes 24 inserted on the support frame by multiple pressure caps 13.

[0051] Based on the above implementation, a contact limit sensor 9 and a controller are also included. The contact limit sensor 9 is disposed on the upper surface of the first support rod 10 of the positioning bracket 27 and located directly below the second support rod 12. The contact limit sensor 9 and the stepper motor 16 are electrically connected to the controller. When the second support rod 12 approaches the first support rod 10, the second support rod 12 can contact the contact limit sensor 9. The contact limit sensor 9 senses the contact signal and transmits it to the controller. The controller controls the stepper motor 16 to pause according to the signal information, thereby controlling the moving distance of the pressing bracket 26, which is beneficial for controlling the extrusion amount.

[0052] Based on the above implementation, the locking mechanism includes multiple limiting holes 3 and multiple limiting bolts 4. The multiple limiting holes 3 are arranged sequentially along the axial direction of the support column 5 of the first slide groove 6. The multiple limiting holes 3 all penetrate the side wall of the first slide groove 6. The multiple limiting bolts 4 are screwed to the corresponding limiting holes 3 and can pass through the side wall of the first slide groove 6 to press against the first slider 19. In use, the first slider 19 is clamped by rotating the limiting bolt 4 to the length of the corresponding limiting hole 3 to press against the first slider 19 in the first slide groove 6, so that the positioning bracket 27 is locked at a preset height and does not slide. If the positioning bracket 27 needs to slide to adjust the height, the limiting bolt 4 is rotated in the opposite direction to release the first slider 19.

[0053] According to requirements, a locking mechanism can be correspondingly provided for the side wall of each first chute 6, or a locking mechanism can be correspondingly provided for controlling one or two or three of the four first chutes 6. Both can achieve the control of the sliding and positioning of the positioning bracket 27, which are within the scope included in the concept of the present utility model.

[0054] On the basis of the above implementation manner, the two second cross bars 11 are located on the two long side frames of the rectangular frame structure, and the two first cross bars 7 are located on the two wide side frames of the rectangular frame structure, which is beneficial to increasing the number of batch collection positions.

[0055] On the basis of the above implementation manner, the plurality of gland covers 13 and the plurality of spacer bars 8 are both made of transparent materials. A conspicuous edge line is provided at the lower edge of the gland cover 13, and a conspicuous edge line is provided at the upper edge of the spacer bar 8, which is more conducive to observation. The conspicuous edge line is, for example, a black, yellow or red line.

[0056] When using the device of the present utility model to collect animal serum samples, the technician first goes to the site to collect blood. Connect the connecting portion 20 of the blood collection syringe 24 with the needle 29. After batch blood collection is completed, the syringe 24 after the needle 29 and the core rod 28 are disassembled is put into the centrifuge for batch centrifugation operation. After centrifugation is completed, start the forward rotation of the stepping motor 16 to slide the lower pressing bracket 26 upward to a preset height, pause the stepping motor 16, and the lower pressing bracket 26 is stationary. At this time, it is the first set height for placing the syringe 24 into the support frame, and the first set height is greater than the height of the push rod 25 plus the height of the syringe 24. Then take out the batch of centrifuged and stratified blood collection syringes 24. Without disassembling the sampling end cover at the upper end of the syringe 24, directly put the batch of syringes 24 into the "匚"-shaped rectangular space through one opening on one side, and pass the through hole at the bottom end of the syringe 24 through the push rod 25, and make the upper end surface of the push rod 25 press against the central groove at the bottom of the piston 23 in the syringe 24.

[0057] Then rotate the limit bolt 4 to loosen the first slider 19 of the positioning bracket 27, so that the positioning bracket 27 can slide along the axial direction of the support column 5. Slide the upper edge of the positioning bracket 27 to be flush with the lower edge of the conical sampling end cover, or flush with the lower edge of the conical top of the syringe 24, or flush with the root of the connecting portion 20 of the syringe 24. Then use the limit bolt 4 at this position to press and clamp the first slider 19 of the positioning bracket 27, so that the positioning bracket 27 is locked and fixed at this position.

[0058] Then, the stepper motor 16 is started to reverse, and the pressing bracket 26 moves closer to the syringe 24 along the axis of the four pillars 5. The connecting part 20 at the top of the syringe 24 passes through the through hole 14 of the corresponding pressure cap 13, and the lower surface of the pressure cap 13 of the pressing bracket 26 abuts against the sampling end cap of the syringe 24. At the same time, the second support rod 12 approaches or contacts the first support rod 10, and the second support rod 12 contacts the contact limit sensor 9 of the first support rod 10. The contact limit sensor 9 senses the contact signal and transmits it to the controller. The controller controls the stepper motor 16 to stop according to the signal information, and the pressing bracket 26 stops. At this time, the pressing bracket 26 reaches the second set height to realize batch support of the syringe 24. Then, one end of the guide tube is connected to the connecting part 20, and the other end is connected to the EP tube with the corresponding number.

[0059] Then, based on the position of the serum liquid level inside the syringe 24, the upper edge of the positioning bracket 27 is slid to be level with the serum liquid level and then fixed, using the limiting bolt 4 of the locking mechanism described above.

[0060] Then, the stepper motor 16 is started to reverse, and the lower support 26 continues to move along the axis of the four pillars 5 towards the syringe 24, applying pressure to the syringe 24 along the axis towards the push rod 25 and causing the push rod 25 to push the piston 23 to move a preset displacement towards the top of the syringe 24. At the same time, the second support rod 12 approaches or contacts the first support rod 10, and the second support rod 12 contacts the contact limit sensor 9 of the first support rod 10. The contact limit sensor 9 senses the contact signal and transmits it to the controller. The controller controls the stepper motor 16 to stop according to the signal information, and the lower support 26 stops. At this time, the lower support 26 reaches the third set height (also called the zero position).

[0061] Then, collect the required amount of serum sample (usually 1-2 ml into an EP tube to test one item), and fix the upper edge of the positioning bracket 27 to the scale line where the distance between the upper edge of the positioning bracket 27 and the lower edge of the lower bracket 26 is 1-2 ml, using the same operation as above.

[0062] Then, the stepper motor 16 is started to reverse, and the lower support 26 continues to move along the axis of the four pillars 5 towards the syringe 24, applying pressure to the syringe 24 along the axis towards the push rod 25, causing the push rod 25 to push the piston 23 to move a preset displacement towards the top of the syringe 24. At the same time, the second support rod 12 approaches or contacts the first support rod 10, and the second support rod 12 contacts the contact limit sensor 9 of the first support rod 10. The contact limit sensor 9 senses the contact signal and transmits it to the controller. The controller controls the stepper motor 16 to pause according to the signal information, and the lower support 26 stops. This allows the serum in the syringe 24 to flow out through the through hole of the syringe 24 connection part 20 through the guide tube in a set amount of serum, realizing batch collection, effectively improving the efficiency of serum separation and collection, without relying on the skilled skills of technicians in pouring, tilting position and pouring volume, etc., which is quick to learn and easy to operate.

[0063] When it is necessary to collect samples for other tests, a new batch of EP tubes can be connected. The upper edge of the positioning bracket 27 is slid down to the scale line with a distance of 1-2 ml between it and the lower edge of the pressing bracket 26 and fixed. The stepper motor 16 is then started to reverse, and another batch of serum samples can be collected. This meets the needs of collecting samples for multiple tests, is easy to operate, has high batch separation and collection efficiency, and has high practical and promotional value.

[0064] Although the embodiments of this utility model have been disclosed above, they are not limited to the applications listed in the specification and embodiments. It can be applied to various fields suitable for this utility model. Other modifications can be easily made by those skilled in the art.

Claims

1. An animal serum sample separation collection device comprising a blood collector, a needle cylinder top end of the blood collector is provided with a connecting part penetrating through the needle cylinder, characterized in that, Also include: Support frame, including a rectangular bottom plate and four pillars, the four pillars are respectively vertically fixed on the four corners of the upper surface of the bottom plate, so that the four pillars form a rectangular frame structure on the bottom plate, and the upper surface of the bottom plate is vertically provided with a plurality of push rods adapted to the through hole of the bottom end of the needle cylinder, the push rod is used for setting through the through hole of the bottom end of the needle cylinder, and the upper end surface of the push rod abuts against the central groove of the bottom of the piston in the needle cylinder; The lower pressing support is located above the bottom plate and can be connected with the four pillars in the axial direction. The lower pressing support includes two second cross bars, a plurality of pressure covers and a plurality of second supporting rods. The two second cross bars are respectively arranged on the opposite sides of the rectangular frame structure. The plurality of second supporting rods are parallel to each other and cross between the two second cross bars in the same plane. The central part of each second supporting rod is provided with one or two pressure covers. The central through hole of the pressure cover is larger than the outer diameter of the top end connecting part of the needle cylinder and smaller than the inner diameter of the needle cylinder. The through hole is used for passing through the top end connecting part of the needle cylinder directly below the pressure cover. Each push rod corresponds to each pressure cover, and the center axis of the through hole of the push rod and the corresponding pressure cover coincides. The connecting part connects the needle during blood collection and connects the flow guide tube during serum collection.

2. The animal serum sample separation and collection device of claim 1, wherein The lower pressing support connected with the four pillars in the axial direction is that the two second cross bars are parallel to each other and in the same plane, and the plane is parallel to the bottom plate. The square second sliding block is fixed at both ends of each second cross bar. The second sliding groove matched with the second sliding block is arranged on the opposite side surface of the two pillars corresponding to the side of the rectangular frame structure.

3. The animal serum sample separation and collection device of claim 2, wherein The driving mechanism for driving the lower pressing support to slide in the axial direction of the four pillars is also included. The driving mechanism includes a ball screw and a stepping motor. The ball screw is arranged in the second sliding groove in the axial direction of the pillar. One end of the ball screw is rotatably connected with the upper wall of the second sliding groove through a bearing, and the other end is connected with the output end of the stepping motor. The second sliding block is fixedly connected with the nut of the ball screw.

4. The animal serum sample separation and collection device of claim 3, wherein The through hole of the pressure cover is a conical through hole with a large lower part and a small upper part. The inner diameter of the upper opening of the conical through hole is equal to or slightly larger than the outer diameter of the root part of the top end connecting part of the needle cylinder. The inner diameter of the lower opening of the conical through hole is equal to or slightly larger than the inner diameter of the needle cylinder.

5. The animal serum sample separation and collection device of any one of claims 1-4, wherein, The positioning support is located between the pressing support and the bottom plate and is connected in sliding along the axis of the four supporting columns, the positioning support, the pressing support and the bottom plate are parallel to each other; the positioning support comprises two first horizontal rods, a plurality of spacing bars and a first supporting rod, the two first horizontal rods are arranged on the other two opposite sides of the rectangular frame structure respectively, the first supporting rod is transversely arranged between the two first horizontal rods, the plurality of spacing bars are arranged on one side or both sides of the first supporting rod at equal intervals and perpendicularly, the plurality of spacing bars are parallel to each other and in the same plane as the first supporting rod and the first horizontal rods, the distance between two adjacent spacing bars is equal to or slightly greater than the outer diameter of the needle cylinder, the rectangular space between two adjacent spacing bars corresponds to each pressing cover one by one, and the rectangular median line of the rectangular space is perpendicular to the central axis of the through hole of the corresponding pressing cover, the rectangular median line is parallel to the spacing bar.

6. The animal serum sample separation and collection device of claim 5, wherein The positioning support connected in sliding along the axis of the four supporting columns is that the two first horizontal rods are parallel to each other and in the same plane, the plane is parallel to the bottom plate, square first sliding blocks are fixed at both ends of each first horizontal rod, first sliding grooves matched with the first sliding blocks are arranged on the opposite sides of the two supporting columns corresponding to the sides of the rectangular frame structure; a locking mechanism for clamping and releasing the first sliding blocks is arranged on the supporting column where the first sliding groove is arranged.

7. The animal serum sample separation and collection device of claim 6, wherein A contact type limit sensor and a controller are further included, the contact type limit sensor is arranged on the upper surface of the first supporting rod of the positioning support and is located directly below the second supporting rod, the contact type limit sensor and the stepping motor are electrically connected with the controller.

8. The animal serum sample separation and collection device of claim 7, wherein, The locking mechanism comprises a plurality of limit holes and a plurality of limit bolts, the plurality of limit holes are arranged in sequence along the axis of the supporting column of the first sliding groove, the plurality of limit holes all penetrate the side wall of the first sliding groove, the plurality of limit bolts are correspondingly screwed with the plurality of limit holes and can press the first sliding block through the side wall of the first sliding groove.

9. An animal serum sample separation and collection device as claimed in any one of claims 6 to 8, wherein, The two second horizontal rods are located on the two side long frames of the rectangular frame structure, and the two first horizontal rods are located on the two side wide frames of the rectangular frame structure.

10. The animal serum sample separation and collection device of claim 9, wherein The plurality of pressing covers and the plurality of spacing bars are made of transparent material, the lower edge of the pressing cover is provided with a conspicuous edge line, and the upper edge of the spacing bar is provided with a conspicuous edge line.

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