Constant-temperature incubator

Abstract

The utility model discloses a constant-temperature incubator. The constant-temperature incubator comprises a sealed outer box, a constant-temperature inner box, a sliding tray, a pore plate bracket, a heating device and a driving device, the pore plate support is arranged on the sliding tray in the constant-temperature inner box, the cooling pipe is arranged at the bottom of the pore plate support, effective cooling operation can be achieved, the cooling pipe is uniform in temperature change in a liquid cooling mode, unstable temperature change of heating and cooling operation cannot be caused, and the top of the pore plate support is used for containing the pore plate, so that the service life of the pore plate is prolonged. The temperature of the pore plate can be adjusted more accurately, the heating device is arranged on the outer surface of the constant-temperature inner box in a matched mode, the temperature of the pore plate is mildly adjusted, high integration is achieved, and the occupied space of the constant-temperature incubator is effectively reduced.

Description

Technical Field

[0001] This application relates to the field of cell culture equipment technology, specifically to a constant temperature incubator. Background Technology

[0002] Cell culture typically requires a constant temperature environment, thus isothermal culture devices are commonly used. Most current isothermal cell culture devices only use heating equipment for heating, while cooling relies on natural cooling, resulting in slow cooling rates. Although a cell isothermal culture device, such as the one described in patent 202111418033.4, combines heating and cooling equipment, the large size of these devices leads to a large footprint, complex operation, and unstable temperature changes during heating and cooling. Using direct heating or cold air for temperature control results in rapid temperature changes, making gentle temperature regulation impossible, and repeated rapid temperature fluctuations can lead to cell death. Furthermore, cold air temperature control can contaminate cells, reducing the practicality of the isothermal cell culture device. Therefore, we need an isothermal incubator that can gently regulate temperature and has a smaller footprint. Utility Model Content

[0003] This application provides a constant temperature incubator, which aims to solve the problems of large space occupation and unstable temperature regulation of heating and cooling equipment in the prior art, so as to achieve gentle temperature regulation and reduce the size of the equipment.

[0004] This application provides a constant temperature incubator, including:

[0005] The sealed outer casing contains a drive area and a storage area.

[0006] A constant temperature inner chamber is provided within the accommodating area, and the constant temperature inner chamber has an opening on the side opposite to the driving area;

[0007] A sliding tray is slidably disposed inside the constant temperature inner chamber. The sliding tray is provided with a cover plate at the position opposite the opening of the chamber. The cover plate seals the opening of the chamber when the sliding tray is housed inside the constant temperature inner chamber.

[0008] A perforated plate support is provided on the sliding tray. The bottom of the perforated plate support is provided with a cooling pipe, and the top of the perforated plate support is used to place the perforated plate.

[0009] A heating device is located on the outer surface of the constant temperature inner chamber;

[0010] A drive unit, located within the drive area, passes through the constant temperature inner chamber and connects to the pull-out sliding tray; the drive unit drives the pull-out sliding tray to extend into or out of the constant temperature inner chamber.

[0011] In some embodiments, the constant temperature incubator further includes:

[0012] A water pump is located within the drive area;

[0013] The liquid supply pipeline connects the water pump and the cooling pipe.

[0014] In some embodiments, the cooling pipes are arranged in an S-shape, with inlet and outlet ports formed at both ends on the side of the orifice plate support; the liquid supply pipeline includes a flexible inlet pipeline and a flexible return pipeline, with the two ends of the flexible inlet pipeline connected to the water pump and the inlet port respectively, and the two ends of the flexible return pipeline connected to the water pump and the outlet port respectively.

[0015] In some embodiments, the heating device includes a first heating plate disposed on top of the constant temperature inner chamber and located between the constant temperature inner chamber and the sealed outer chamber.

[0016] In some embodiments, the heating device includes a second heating plate disposed at the bottom of the constant temperature inner chamber and located between the constant temperature inner chamber and the sealed outer chamber.

[0017] In some embodiments, the constant temperature incubator further includes:

[0018] The controller is located within the drive area; a temperature sensor is also provided on the orifice plate bracket, and the controller is electrically connected to the temperature sensor, the heating device, the water pump and the drive device. The controller has control buttons on the outer surface of the sealed outer casing.

[0019] In some embodiments, the top edge of the perforated plate support is provided with a limiting protrusion, the shape and size of which are adapted to the shape and size of the bottom of the perforated plate.

[0020] In some embodiments, the orifice plate has multiple test tube cavity structures, each test tube cavity structure has a rectangular opening and a hemispherical bottom, and the top of the orifice plate support has multiple grooves, each groove being hemispherical, and the grooves are arranged one-to-one with the test tube cavity structures.

[0021] In some embodiments, the sliding tray includes a slide rail, a tray plate, and a cover plate. The slide rail is installed inside the constant temperature inner chamber. The bottom surface of the tray plate is connected to the slide rail. The perforated plate bracket is provided on the top surface of the tray plate, and the cover plate is provided on the side surface of the tray plate.

[0022] In some embodiments, the drive device includes a motor and a screw, the motor being fixed within the drive area, one end of the screw being connected to the motor, and the other end of the screw being threadedly connected to the support plate.

[0023] The constant temperature incubator provided in this application embodiment has a perforated plate support set on a sliding tray inside the constant temperature inner chamber. The bottom of the perforated plate support is equipped with a cooling pipe, which can achieve effective cooling operation. Moreover, the liquid cooling method of the cooling pipe results in uniform temperature change and will not cause unstable temperature changes during heating and cooling operations. Furthermore, the top of the perforated plate support is used to place the perforated plate, which can more accurately adjust the temperature of the perforated plate. In conjunction with the heating device set on the outer surface of the constant temperature inner chamber, the temperature of the perforated plate can be gently adjusted. In addition, the high integration effectively reduces the space occupied by the constant temperature incubator. Attached Figure Description

[0024] The technical solution and other beneficial effects of this application will become apparent from the following detailed description of specific embodiments in conjunction with the accompanying drawings.

[0025] Figure 1 This is a schematic diagram of the structure of the constant temperature incubator provided in the embodiments of this application;

[0026] Figure 2 This is a schematic diagram of the structure of a perforated plate placed inside a constant temperature incubator provided in an embodiment of this application;

[0027] Figure 3 A top view of the internal structure of a constant temperature incubator provided in an embodiment of this application;

[0028] Figure 4 A bottom view of the internal structure of a constant temperature incubator provided in an embodiment of this application;

[0029] Figure 5 A side cross-sectional view of the internal structure of a constant temperature incubator provided in an embodiment of this application;

[0030] Figure 6 This is a schematic diagram of the internal structure of the constant temperature chamber provided in the embodiments of this application;

[0031] Figure 7 This is a partial structural diagram of the interior of the constant temperature chamber provided in an embodiment of this application;

[0032] Figure 8 A bottom view of the structure of a perforated plate mounted on a perforated plate support provided in an embodiment of this application;

[0033] Figure 9 This is a schematic diagram of the internal flow channel structure of the orifice plate support provided in the embodiments of this application;

[0034] Figure 10 This is a top view of the perforated plate support provided in an embodiment of this application;

[0035] Figure 11 This is a bottom view of the perforated plate provided in an embodiment of this application.

[0036] The markings in the diagram are as follows:

[0037] Sealed outer box 1, drive area 11, containment area 12, constant temperature inner box 2, box opening 21, sliding tray 3, cover plate 31, slide rail 32, support plate 33, perforated plate bracket 4, cooling pipe 41, liquid inlet 411, liquid outlet 412, flow channel 42, temperature sensor 43, limiting protrusion 44, groove 45, heating device 5, first heating plate 51, second heating plate 52, third heating plate 53, drive device 6, motor 61, screw 62, water pump 7, liquid supply pipeline 8, flexible liquid inlet pipeline 81, flexible liquid return pipeline 82, controller 9, control button 91, perforated plate 10, test tube cavity structure 101. Detailed Implementation

[0038] The technical solutions of the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only a part of the embodiments of this application, and not all of them. All other embodiments obtained by those skilled in the art based on the embodiments of this application without creative effort are within the scope of protection of this application.

[0039] In the description of this application, it should be understood that the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Therefore, features defined as "first" or "second" may explicitly or implicitly include one or more of the stated features. In the description of this application, "multiple" means two or more, unless otherwise explicitly specified.

[0040] In the description of this application, it should be noted that, unless otherwise expressly specified and limited, the terms "installation," "connection," and "linking" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection, an electrical connection, or a connection that allows communication between them; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication between two components or the interaction between two components. Those skilled in the art can understand the specific meaning of the above terms in this application according to the specific circumstances.

[0041] In this application, unless otherwise expressly specified and limited, "above" or "below" the second feature can include direct contact between the first and second features, or contact between the first and second features through another feature between them. Furthermore, "above," "over," and "on top" of the second feature includes the first feature being directly above or diagonally above the second feature, or simply indicates that the first feature is at a higher horizontal level than the second feature. "Below," "below," and "under" the second feature includes the first feature being directly below or diagonally below the second feature, or simply indicates that the first feature is at a lower horizontal level than the second feature.

[0042] like Figure 1 , Figure 2 , Figure 3 , Figure 4 , Figure 5 As shown in the figure, this application provides a constant temperature incubator, including: a sealed outer box 1, a constant temperature inner box 2, a sliding tray 3, a perforated plate support 4, a heating device 5, and a driving device 6.

[0043] Specifically, the sealed outer casing 1 has a drive area 11 and a receiving area 12 inside; the constant temperature inner casing 2 is located in the receiving area 12, and the constant temperature inner casing 2 has a box opening 21 on the side opposite to the drive area 11; the sliding tray 3 is slidably located in the constant temperature inner casing 2, and the sliding tray 3 has a cover plate 31 at the position opposite to the box opening 21, and the cover plate 31 seals the box opening 21 when the sliding tray 3 is received in the constant temperature inner casing 2; the perforated plate bracket 4 is located on the sliding tray 3, the bottom of the perforated plate bracket 4 has a cooling pipe 41, and the top of the perforated plate bracket 4 is used to place the perforated plate 10; the heating device 5 is located on the outer surface of the constant temperature inner casing 2; the drive device 6 is located in the drive area 11, passes through the constant temperature inner casing 2 and is connected to the pull-out sliding tray 3; the drive device 6 drives the pull-out sliding tray 3 to extend or extend from the constant temperature inner casing 2.

[0044] The sealed outer casing 1 is divided into two separate areas: a drive area 11 and a containment area 12. The drive area 11 is located at the bottom of the sealed outer casing 1, and the containment area 12 is located at the opening 21 of the sealed outer casing 1, which is not only aesthetically pleasing but also convenient to operate. The sealed outer casing 1 is covered by a constant temperature inner casing 2, which can achieve a heat preservation effect.

[0045] The perforated plate support 4 is installed on the sliding tray 3 inside the constant temperature inner chamber 2. The bottom of the perforated plate support 4 is equipped with a cooling pipe 41, which can achieve effective cooling. The liquid cooling method of the cooling pipe 41 results in uniform temperature change and will not cause unstable temperature changes during heating and cooling operations. Moreover, the top of the perforated plate support 4 is used to place the perforated plate 10, which can more accurately adjust the temperature of the perforated plate 10. In conjunction with the heating device 5 located on the outer surface of the constant temperature inner chamber 2, the temperature of the perforated plate 10 can be gently adjusted. Furthermore, the high integration effectively reduces the space occupied by the constant temperature incubator.

[0046] Preferably, the cooling pipe 41 uses water or coolant to cool the perforated plate support 4. The perforated plate support 4 is made of metal to facilitate heat conduction. The perforated plate 10 is made of metal or plastic to hold cell solutions.

[0047] like Figure 6 , Figure 7 As shown, the constant temperature incubator also includes a water pump 7 and a liquid supply pipeline 8. The water pump 7 is located within the drive area 11; the liquid supply pipeline 8 connects the water pump 7 and the cooling pipe 41.

[0048] Specifically, such as Figure 8 , Figure 9 As shown, the cooling pipe 41 is arranged in an S-shape, with its two ends forming an inlet 411 and an outlet 412 on the side of the orifice plate support 4. The liquid supply pipeline 8 includes a flexible inlet pipeline 81 and a flexible return pipeline 82. The two ends of the flexible inlet pipeline 81 are respectively connected to the water pump 7 and the inlet 411, and the two ends of the flexible return pipeline 82 are respectively connected to the water pump 7 and the outlet 412.

[0049] Among them, such as Figure 6 , Figure 7 As shown, the liquid supply line 8 includes a flexible inlet line 81 and a flexible return line 82, which enables the water pump 7 and the end of the cooling pipe 41 to be stably connected through flexible deformation during the process of the drive device 6 driving the sliding tray 3 to extend or retract from the constant temperature inner chamber 2. Preferably, the inlet 411 and the outlet 412 are located on the same side of the orifice plate support 4, and the inlet 411 and the outlet 412 are spaced from the edge of the orifice plate support 4 to avoid interfering with the sealing of the chamber opening 21 by the cover plate 31 when the sliding tray 3 is housed in the constant temperature inner chamber 2.

[0050] like Figure 3 As shown, the heating device 5 includes a first heating plate 51, which is disposed on the top of the constant temperature inner box 2 and is located between the constant temperature inner box 2 and the sealed outer box 1.

[0051] like Figure 4 As shown, the heating device 5 includes a second heating plate 52, which is disposed at the bottom of the constant temperature inner box 2 and is located between the constant temperature inner box 2 and the sealed outer box 1.

[0052] The placement of the first heating plate 51 and the second heating plate 52 not only effectively heats the perforated plate support 4 and the perforated plate 10 inside the constant temperature inner chamber 2, but also reduces the volume of the constant temperature incubator.

[0053] Preferred, such as Figure 4 , Figure 8 , Figure 9 As shown, the heating device 5 includes a third heating plate 53, which serves as the base plate of the cooling pipe 41. The bottom surface of the perforated plate bracket 4 is provided with a flow channel 42, which allows the third heating plate 53 to seal the flow channel 42 to form the cooling pipe 41. This can further improve the heating efficiency of the third heating plate 532 for water or coolant in the cooling pipe 41 and enable faster temperature adjustment.

[0054] like Figure 3 , Figure 5 As shown, the constant temperature incubator also includes a controller 9. The controller 9 is located within the drive area 11; a temperature sensor 43 is also provided on the perforated plate support 4, and the controller 9 is electrically connected to the temperature sensor 43, the heating device 5, the water pump 7, and the drive device 6, as shown. Figure 1 As shown, the controller 9 has control buttons 91 on the outer surface of the sealed outer casing 1.

[0055] The controller 9 is connected to the first heating plate 51, the second heating plate 52, and the third heating plate 53. When the temperature of the orifice plate support 4 detected by the temperature sensor 43 is lower than the target temperature threshold, the controller 9 controls the first heating plate 51, the second heating plate 52, and the third heating plate 53 to heat; otherwise, heating is stopped. Similarly, the controller 9 is connected to the water pump 7. When the temperature of the orifice plate support 4 detected by the temperature sensor 43 is higher than the target temperature threshold, the controller 9 controls the water pump 7 to start cooling; otherwise, the water pump 7 stops to maintain the temperature.

[0056] like Figure 10 As shown, the top edge of the perforated plate support 4 is provided with a limiting protrusion 44, the shape and size of which are adapted to the shape and size of the bottom of the perforated plate 10. The limiting protrusion 44 is used to clamp the bottom of the perforated plate 10 to fix the perforated plate 10.

[0057] Wherein, an accommodating space for accommodating the orifice plate 10 is formed between the orifice plate support 4 and the top surface of the constant temperature inner chamber 2, and the height of the orifice plate 10 is less than or equal to the distance between the orifice plate support 4 and the top surface of the constant temperature inner chamber 2.

[0058] like Figure 10 , Figure 11 As shown, the orifice plate 10 has multiple test tube cavity structures 101, each with a rectangular opening and a hemispherical bottom. The top of the orifice plate support 4 has multiple hemispherical grooves 45, each corresponding to a test tube cavity structure 101. This allows the test tube cavity structure 101 to maintain a sealed contact with the orifice plate support 4, achieving good heat transfer.

[0059] like Figure 5 , Figure 6 As shown, the sliding tray 3 includes a slide rail 32, a tray 33 and a cover plate 31. The slide rail 32 is installed inside the constant temperature inner chamber 2. The bottom surface of the tray 33 is connected to the slide rail 32. The perforated plate bracket 4 is provided on the top surface of the tray 33. The cover plate 31 is provided on the side of the tray 33.

[0060] like Figure 5 , Figure 6 As shown, the driving device 6 includes a motor 61 and a screw 62. The motor 61 is fixed in the driving area 11, one end of the screw 62 is connected to the motor 61, and the other end of the screw 62 is threaded to the tray 33. The controller 9 can control the sliding tray 3 to extend or retract from the constant temperature inner chamber 2 by controlling the rotation direction of the motor 61.

[0061] The constant temperature incubator provided in this application embodiment has an orifice plate support 4 set on a sliding tray 3 inside the constant temperature inner chamber 2. The bottom of the orifice plate support 4 is provided with a cooling pipe 41, which can achieve effective cooling operation. The cooling pipe 41 is liquid-cooled and the temperature change is uniform, which will not cause unstable temperature changes during heating and cooling operations. Moreover, the top of the orifice plate support 4 is used to place the orifice plate 10, which can more accurately adjust the temperature of the orifice plate 10. In conjunction with the heating device 5 set on the outer surface of the constant temperature inner chamber 2, the temperature of the orifice plate 10 can be gently adjusted. Furthermore, the high integration effectively reduces the space occupied by the constant temperature incubator.

[0062] In the above embodiments, the descriptions of each embodiment have different focuses. For parts not described in detail in a certain embodiment, please refer to the relevant descriptions in other embodiments.

[0063] The above provides a detailed description of a constant temperature incubator provided in the embodiments of this application. Specific examples have been used to illustrate the principles and implementation methods of this application. The description of the above embodiments is only for the purpose of helping to understand the technical solutions and core ideas of this application. Those skilled in the art should understand that they can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. These modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of this application.

Claims

1. An incubator, characterized in that, include: The sealed outer casing contains a drive area and a storage area. A constant temperature inner chamber is provided within the accommodating area, and the constant temperature inner chamber has an opening on the side opposite to the driving area; A sliding tray is slidably disposed inside the constant temperature inner chamber. The sliding tray is provided with a cover plate at the position corresponding to the opening of the chamber. The cover plate seals the opening of the chamber when the sliding tray is housed inside the constant temperature inner chamber. A perforated plate support is provided on the sliding tray. The bottom of the perforated plate support is provided with a cooling pipe, and the top of the perforated plate support is used to place the perforated plate. A heating device is located on the outer surface of the constant temperature inner chamber; A drive unit, located within the drive area, passes through the constant temperature inner chamber and connects to the sliding tray; the drive unit drives the sliding tray to extend into or out of the constant temperature inner chamber.

2. The constant temperature incubator of claim 1, wherein, The constant temperature incubator also includes: A water pump is located within the drive area; The liquid supply pipeline connects the water pump and the cooling pipe.

3. The constant temperature incubator of claim 2, wherein, The cooling pipes are arranged in an S-shape, with inlet and outlet ports formed at both ends on the side of the orifice plate support. The liquid supply pipeline includes a flexible inlet pipeline and a flexible return pipeline. The two ends of the flexible inlet pipeline are connected to the water pump and the inlet port, respectively, and the two ends of the flexible return pipeline are connected to the water pump and the outlet port, respectively.

4. The constant temperature incubator of claim 1, wherein, The heating device includes a first heating plate, which is disposed on the top of the constant temperature inner chamber and located between the constant temperature inner chamber and the sealed outer chamber.

5. The constant temperature incubator of claim 4, wherein, The heating device includes a second heating plate, which is disposed at the bottom of the constant temperature inner chamber and located between the constant temperature inner chamber and the sealed outer chamber.

6. The constant temperature incubator of claim 2, wherein, The constant temperature incubator also includes: The controller is located within the drive area; a temperature sensor is also provided on the orifice plate bracket, and the controller is electrically connected to the temperature sensor, the heating device, the water pump and the drive device. The controller has control buttons on the outer surface of the sealed outer casing.

7. The constant temperature incubator of claim 1, wherein, The top edge of the perforated plate support is provided with a limiting protrusion, the shape and size of which are adapted to the shape and size of the bottom of the perforated plate.

8. The constant temperature incubator of claim 1, wherein, The orifice plate has multiple test tube cavity structures, each with a rectangular opening and a hemispherical bottom. The top of the orifice plate support has multiple grooves, each hemispherical, and each groove corresponds to a test tube cavity structure.

9. The constant temperature incubator of claim 1, wherein, The sliding tray includes a slide rail, a tray plate, and a cover plate. The slide rail is installed inside the constant temperature inner chamber. The bottom surface of the tray plate is connected to the slide rail. The perforated plate bracket is provided on the top surface of the tray plate, and the cover plate is provided on the side of the tray plate.

10. The constant temperature incubator of claim 9, wherein, The driving device includes a motor and a screw. The motor is fixed in the driving area, one end of the screw is connected to the motor, and the other end of the screw is threaded to the support plate.

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