Constant-temperature oscillator for cell culture

By combining a hot air blower and a ring-shaped electric slide rail in a constant-temperature oscillator for rotary heating, and a stepper motor and a vibrator for oscillation, the problem of uneven heat distribution was solved, achieving uniform heating and oscillation within the culture vessel and improving the quality of cell culture.

CN223974110UActive Publication Date: 2026-03-06河南志宸生物科技有限公司
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-01-08
Publication Date
2026-03-06

AI Technical Summary

Technical Problem

Existing constant temperature oscillators suffer from uneven heat distribution during heating, which affects cell culture results.

Method used

A constant temperature component combining a hot air blower and a ring-shaped electric slide rail is used for rotary moving heating, and an oscillation component combining a stepper motor and a vibrator is used to realize the eccentric rotation and up-and-down vibration of the culture container, ensuring temperature uniformity and oscillation effect.

Benefits of technology

Uniform heating and oscillation within the culture vessel were achieved, improving the efficiency and effectiveness of cell culture.

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Abstract

The utility model discloses a constant-temperature oscillator for cell culture, and particularly relates to the technical field of constant-temperature oscillators, which comprises a case, a cover is hinged to the top of the case, an oscillation box is arranged on the inner side of the case, a placing frame is fixedly arranged on the inner side of the oscillation box, and an oscillation assembly is arranged at the bottom of the oscillation box. An annular sliding frame is arranged at the top of the oscillation box and fixedly connected with the machine box, a sliding block is arranged on the front side of the annular sliding frame in a sliding mode, and a constant-temperature assembly is arranged at the bottom of the sliding block. According to the utility model, the constant-temperature component is arranged, so that the constant-temperature oscillator has the functions of more uniformly heating and carrying out constant-temperature treatment on air in the case in a rotary moving manner, thereby solving the problems that the constant-temperature effect of the constant-temperature oscillator is usually realized by heating the air in the sealed case body and then preserving heat, but the heating element is fixed in position; the position for generating heat is fixed, and uneven heating in the sealing box is easily caused, so that the cell culture effect is influenced.
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Description

Technical Field

[0001] This utility model relates to the field of thermostatic oscillator technology, and more specifically, to a thermostatic oscillator for cell culture. Background Technology

[0002] The key to cell growth is providing appropriate temperature and oxygen supply. A thermostatic shaker can control the culture temperature at around 37°C. At the same time, the thermostatic shaker can also promote cell metabolism and proliferation by vibrating and stirring the cells and culture medium, thereby achieving the purpose of cell culture. When the controller heats the liquid in the water bath of the incubator, the liquid in the water bath is basically still, which leads to uneven heating of the liquid, increases the energy consumption required for heating and affects efficiency.

[0003] According to patent publication number CN221877057U, a constant temperature shaker with cell culture function is disclosed, including a shaker body with a water bath chamber and a shaking disk for carrying materials. The shaking disk can oscillate back and forth in the water bath chamber. A stirring component is provided inside the water bath chamber and below the shaking disk. This structure can agitate the liquid in the water bath chamber by setting the stirring component at the bottom of the water bath chamber of the shaker body, so that the liquid is heated more evenly and the efficiency of water bath heating is improved.

[0004] However, in actual use, the temperature control effect of a constant temperature shaker is usually achieved by heating and then maintaining the temperature of the air in the sealed chamber. However, since the heating element is in a fixed position and the heat generation location is fixed, it is easy to cause uneven heating inside the sealed chamber, which affects the cell culture effect. Utility Model Content

[0005] In order to overcome the above-mentioned defects of the prior art, the present invention provides a constant temperature oscillator for cell culture to solve the problems mentioned in the background art.

[0006] To achieve the above objectives, the present invention provides the following technical solution: a constant temperature shaker for cell culture, comprising a chassis, a cover hinged to the top of the chassis, a shaking box provided inside the chassis, a placement rack fixedly provided inside the shaking box, a shaking assembly provided at the bottom of the shaking box, an annular slide provided at the top of the shaking box, the annular slide being fixedly connected to the chassis, a slider slidably provided on the front side of the annular slide, and a constant temperature assembly provided at the bottom of the slider.

[0007] As a further description of the above technical solution:

[0008] The temperature control component includes an annular frame fixed to the inner wall of the chassis, an annular electric slide rail fixedly mounted on the top of the annular frame, a slide table fixedly mounted on the top of the annular electric slide rail, a connecting plate fixedly mounted on the top of the slide table, and a hot air blower fixedly mounted on the top of the connecting plate.

[0009] As a further description of the above technical solution:

[0010] The hot air duct is provided through the output end of the hot air blower. One end of the hot air duct is connected to an arc-shaped exhaust shell. The arc-shaped exhaust shell is fixedly connected to the slider. Multiple nozzles are connected through the front side of the arc-shaped exhaust shell.

[0011] As a further description of the above technical solution:

[0012] The oscillation assembly includes a positioning plate fixed to the bottom of the oscillation box, a swing rod fixed to the bottom of the positioning plate, a rotating shaft fixed to the bottom of the swing rod, an oscillation frame rotatably connected to the bottom of the rotating shaft, and the rotating shaft passes through the oscillation frame and extends to the bottom of the oscillation frame.

[0013] As a further description of the above technical solution:

[0014] An oscillating plate is fixedly installed at the bottom of the oscillating frame, a stepper motor is fixedly installed at the top of the oscillating plate, a reducer is fixedly installed at the output end of the stepper motor, and the output end of the reducer is fixedly connected to the rotating shaft.

[0015] As a further description of the above technical solution:

[0016] A vibrator is fixedly installed at the bottom of the oscillating plate, and multiple springs are fixedly installed at the bottom of the oscillating plate, with each spring being fixedly connected to the machine casing.

[0017] As a further description of the above technical solution:

[0018] Each of the springs has a limiting post on its inner side, and the limiting post is fixedly connected to the chassis.

[0019] The technical effects and advantages of this utility model are as follows:

[0020] By setting up a constant temperature component, compared with existing technologies, the air inside the chamber can be uniformly heated and kept at a constant temperature through the combined action of a hot air blower and a ring-shaped electric slide rail, thereby enabling better uniform and constant temperature treatment of the culture container.

[0021] By setting up an oscillation component, compared with existing technologies, the combined action of a stepper motor and a vibrator enables the oscillation box and culture container to rotate eccentrically while vibrating up and down, increasing the direction of movement of the culture container and thus allowing the cells inside the culture container to be subjected to more uniform oscillation. Attached Figure Description

[0022] Figure 1 This is a schematic diagram of the overall structure of this utility model.

[0023] Figure 2 This is a cross-sectional view of the chassis structure of this utility model.

[0024] Figure 3 This is a cross-sectional view of the oscillation box structure of this utility model.

[0025] Figure 4 This is a cross-sectional view of the oscillator frame of this utility model.

[0026] The attached diagram is labeled as follows: 1. Chassis; 2. Cover; 3. Vibration box; 4. Placement rack; 5. Circular slide; 6. Slider; 7. Circular frame; 8. Circular electric slide rail; 9. Slide table; 10. Connecting plate; 11. Hot air blower; 12. Hot air duct; 13. Arc-shaped exhaust shell; 14. Nozzle; 15. Positioning plate; 16. Swing rod; 17. Rotating shaft; 18. Vibration frame; 19. Vibration plate; 20. Stepper motor; 21. Reducer; 22. Vibrator; 23. Spring; 24. Limiting post. Detailed Implementation

[0027] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0028] As attached Figure 1-4 The present invention relates to a thermostatic shaker for cell culture, comprising a chassis 1, an organic cover 2 hinged to the top of the chassis 1, a shaker box 3 inside the chassis 1, a placement rack 4 fixedly mounted inside the shaker box 3, a shaker assembly at the bottom of the shaker box 3, an annular slide 5 at the top of the shaker box 3, the annular slide 5 being fixedly connected to the chassis 1, a slider 6 slidingly mounted on the front side of the annular slide 5, and a thermostatic assembly at the bottom of the slider 6.

[0029] In some embodiments, according to Figure 2 , 3 As shown, the constant temperature component includes an annular frame 7 fixed to the inner wall of the housing 1, an annular electric slide rail 8 fixedly provided on the top of the annular frame 7, a slide table 9 provided on the top of the annular electric slide rail 8, a connecting plate 10 fixedly provided on the top of the slide table 9, and a hot air blower 11 fixedly provided on the top of the connecting plate 10.

[0030] In some embodiments, according to Figure 3As shown, a hot air pipe 12 is provided through the output end of the hot air blower 11. One end of the hot air pipe 12 is connected to an arc-shaped exhaust shell 13. The arc-shaped exhaust shell 13 is fixedly connected to the slider 6. Multiple nozzles 14 are connected through the front side of the arc-shaped exhaust shell 13. The annular electric slide rail 8 enables the hot air discharged from the nozzles 14 to rotate around the outside of the culture container for heating and constant temperature treatment.

[0031] In some embodiments, according to Figure 2 , 4 As shown, the oscillation assembly includes a positioning plate 15 fixed to the bottom of the oscillation box 3. A swing rod 16 is fixedly provided at the bottom of the positioning plate 15. A rotating shaft 17 is fixedly provided at the bottom of the swing rod 16. An oscillation frame 18 is rotatably connected to the bottom of the rotating shaft 17. The rotating shaft 17 passes through the oscillation frame 18 and extends to the bottom of the oscillation frame 18. The rotation of the rotating shaft 17 causes the swing rod 16 to drive the positioning plate 15 to rotate eccentrically, thereby performing eccentric rotational motion on the culture container.

[0032] In some embodiments, according to Figure 2 , 4 As shown, an oscillating plate 19 is fixedly installed at the bottom of the oscillating frame 18, a stepper motor 20 is fixedly installed at the top of the oscillating plate 19, a reducer 21 is fixedly installed at the output end of the stepper motor 20, and the output end of the reducer 21 is fixedly connected to the rotating shaft 17.

[0033] In some embodiments, according to Figure 2 As shown, a vibrator 22 is fixedly mounted on the bottom of the vibrating plate 19, and multiple springs 23 are fixedly mounted on the bottom of the vibrating plate 19. All the multiple springs 23 are fixedly connected to the housing 1.

[0034] In some embodiments, according to Figure 2 As shown, each of the multiple springs 23 has a limiting post 24 on its inner side. The limiting post 24 is fixedly connected to the housing 1. The springs 23 can provide support and buffer for the entire vibrating plate 19, thereby ensuring that the vibrating machine 22 can work normally.

[0035] The working principle of this utility model is as follows: (refer to the appendix of the instruction manual) Figure 1-4 As shown, the culture container with built-in cells is first placed in the placement rack 4. Then, the stepper motor 20 is started and driven by the reducer 21 to rotate the rotating shaft 17. The rotating shaft 17 then drives the swing arm 16 to rotate. The swing arm 16 then drives the positioning plate 15 to rotate eccentrically. The positioning plate 15 then drives the entire shaking box 3 to rotate eccentrically, thereby making the culture container rotate eccentrically and shake it evenly.

[0036] At the same time, the vibrator 22 is started to drive the oscillation plate 19 to vibrate up and down. The oscillation plate 19 drives the spring 23 to extend and retract at the limit post 24, thereby driving the oscillation frame 18 and the oscillation box 3 to vibrate as a whole, thus cooperating with the stepper motor 20 to make the oscillation of the culture container more uniform and sufficient.

[0037] Then, the hot air blower 11 is started to exhaust hot air from the hot air pipe 12 to the arc-shaped exhaust shell 13 and then spray it out from the nozzle 14. At the same time, the annular electric slide rail 8 is started to drive the slide table 9 to rotate the connecting plate 10. The connecting plate 10 then drives the hot air blower 11 to rotate as a whole, so that the arc-shaped exhaust shell 13 drives the slider 6 to rotate at the annular slide 5. This allows the hot air blower 11 and the arc-shaped exhaust shell 13 to rotate and move to provide more uniform heating and constant temperature treatment for the culture container.

[0038] Finally, it should be noted that the above are merely preferred embodiments of the present utility model and are not intended to limit the present utility model. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. A thermostatic shaker for cell culture comprising a cabinet (1), characterized in that: The machine case (1) top hinged machine cover (2), the machine case (1) inside is equipped with the oscillation box (3), the oscillation box (3) inside fixedly equipped with the rack (4), the oscillation box (3) bottom is equipped with the oscillation subassembly, the oscillation box (3) top is equipped with the annular slide (5), the annular slide (5) with machine case (1) fixed connection, the annular slide (5) front side slidingly equipped with the sliding block (6), the sliding block (6) bottom is equipped with the constant temperature subassembly.

2. The constant temperature shaker for cell culture according to claim 1, wherein: The constant temperature subassembly includes a ring-shaped frame (7) fixed to the inner wall of the machine case (1), a ring-shaped electric slide rail (8) fixedly arranged on the top of the ring-shaped frame (7), a slide table (9) arranged on the top of the ring-shaped electric slide rail (8), a connecting plate (10) fixedly arranged on the top of the slide table (9), and a hot air blower (11) fixedly arranged on the top of the connecting plate (10).

3. A constant temperature shaker for cell culture according to claim 2, wherein: The hot air blower (11) is provided with a hot air pipe (12) penetrating through the output end, one end of the hot air pipe (12) is connected with an arc-shaped air exhaust shell (13), the arc-shaped air exhaust shell (13) is fixedly connected with the sliding block (6), and a plurality of nozzles (14) are penetratingly connected on the front side of the arc-shaped air exhaust shell (13).

4. The constant-temperature shaker for cell culture according to claim 1, characterized in that: The oscillation subassembly includes a positioning plate (15) fixed to the bottom of the oscillation box (3), a swing rod (16) fixedly arranged on the bottom of the positioning plate (15), a rotating shaft (17) fixedly arranged on the bottom of the swing rod (16), and an oscillation frame (18) rotatably connected to the bottom of the rotating shaft (17).

5. A constant temperature shaker for cell culture as claimed in claim 4, wherein: The oscillation frame (18) is fixedly provided with an oscillation plate (19) on the bottom, a stepping motor (20) is fixedly arranged on the top of the oscillation plate (19), a speed reducer (21) is fixedly arranged on the output end of the stepping motor (20), and the output end of the speed reducer (21) is fixedly connected with the rotating shaft (17).

6. A constant temperature shaker for cell culture according to claim 5, wherein: The oscillation plate (19) is fixedly provided with a vibration machine (22) on the bottom, and a plurality of springs (23) are fixedly arranged on the bottom of the oscillation plate (19), and the plurality of springs (23) are fixedly connected with the machine case (1).

7. A constant temperature shaker for cell culture according to claim 6, wherein: A plurality of limit posts (24) are arranged inside the plurality of springs (23), and the limit posts (24) are fixedly connected with the machine case (1).

Citation Information

Patent Citations

  • Constant-temperature oscillator with cell culture function

    CN221877057U