Fixing device for tubular ordered porous film in microscopic light path

Abstract

The utility model discloses a fixing device for a tubular ordered porous film in a microscopic light path, which comprises a main frame and a cover plate, the main frame comprises a fixing plate, and a first tube placing groove, a second tube placing groove and a third tube placing groove of which the diameters are gradually reduced are arranged on the fixing plate at intervals; an upper tube accommodating groove is formed in the cover plate, the upper tube accommodating groove can be aligned with the first tube accommodating groove, the second tube accommodating groove or the third tube accommodating groove so as to form a cavity for fixing a glass tube filled with a tubular ordered porous film, and gaskets are arranged on the inner walls of the upper tube accommodating groove, the first tube accommodating groove, the second tube accommodating groove and the third tube accommodating groove. First screw holes are formed in the positions, close to the first pipe containing groove, the second pipe containing groove and the third pipe containing groove, of the fixing plate, and straight holes corresponding to the first screw holes are formed in the cover piece. The ordered porous film disclosed by the utility model can be stably fixed on a biological sensing platform and can be used for biological sensing research based on an optical interference measurement system; the main frame made of aluminum alloy is hollowed out and thinned, and mass redundancy is reduced as much as possible.

Description

Technical Field

[0001] This utility model pertains to an ordered porous film fixing device, specifically a fixing device for a tubular ordered porous film in a microscopic optical path. Background Technology

[0002] Ordered porous materials refer to a series of materials with pores of uniform size and arranged in an ordered spatial order, and can be inorganic materials or organic polymer materials. Ordered porous materials have broad application prospects in fields such as life sciences, chemistry, information technology, environment, and energy, and provide model carriers for the study of fundamental questions such as interactions between matter, energy transfer, and the behavior of matter under extreme conditions.

[0003] Colloidal crystals are ordered porous nanostructured materials and can also be used as templates for preparing other ordered porous nanostructures, making them widely used ordered porous materials. Researchers both domestically and internationally have conducted extensive work in the hope of developing a method for the large-scale preparation of colloidal crystals with identical properties. These methods include electrostatically induced crystallization, gravity sedimentation, electrodeposition, colloidal orientation growth, physical confinement, and convection self-assembly. However, these methods generally use planar materials as substrates (such as BK7 glass slides), with nanoparticles attached to the substrate surface to obtain planar ordered porous materials. In practice, large glass slides are typically divided into smaller, uniformly shaped rectangular chips, and additional clamping, fixing, and interconnection operations are performed to fabricate these chips into miniature biochemical reaction chambers. This series of operations affects the stability, uniformity, and responsiveness of the constructed micro-region biosensors.

[0004] A planar glass slide can be considered a surface with an infinite radius of curvature, while a cylindrical surface is a surface with a fixed radius of curvature. The region enclosed by a complete cylindrical surface is a tubular space (such as a glass tube). These tubular materials have a naturally more enclosed internal space than planar materials. Nanoparticles can adhere to the inner wall of the tubular glass substrate in the same way to form an ordered porous material, thus freeing the shape of the micro-biochemical reaction cell from being limited to a single chip shape. The size and shape of the tubular glass itself can be used to simulate tubular pathways (such as blood vessels) in living organisms, providing a material basis for the in vitro simulation of in vivo biochemical reactions.

[0005] However, the circular shape of tubular ordered porous films makes them highly susceptible to relative movement with ordered porous layer interferometry sensing systems. Furthermore, the optical interference phenomena of ordered porous films require extremely high stability; even slight movement can affect the acquisition and real-time monitoring of the interference spectrum. Currently, there is no specific device for fixing tubular films onto a biosensing platform, and the problem of achieving stable fixation of tubular films urgently needs to be solved. Utility Model Content

[0006] Purpose of the invention: In order to overcome the shortcomings of the existing technology, the purpose of this utility model is to provide a fixing device for tubular ordered porous films in a microscopic optical path with good stability.

[0007] Technical solution: The present invention provides a fixing device for a tubular ordered porous film in a microscopic optical path, comprising a main frame and a cover plate. The main frame includes a fixing plate, on which a first tube placement groove, a second tube placement groove, and a third tube placement groove with gradually decreasing diameters are spaced apart. An upper tube placement groove is provided on the cover plate, which can be aligned with the first, second, or third tube placement groove to form a cavity for fixing a glass tube containing a tubular ordered porous film. Gaskets are provided on the inner walls of the upper, first, second, and third tube placement grooves.

[0008] Furthermore, screw holes are provided on the fixing plate near the first, second, and third tube placement slots, and straight holes corresponding to the screw holes are provided on the cover plate.

[0009] Furthermore, light-transmitting windows are provided at the first, second, and third tube placement slots on the fixing plate.

[0010] Furthermore, the main frame and cover plate are fixedly connected by bolts. Preferably, the bolts are M4 bolts.

[0011] Furthermore, the main frame also includes several contact feet, which are positioned circumferentially around the fixed plate. The contact foot plates are L-shaped. The thickness of the contact foot plates gradually decreases along the direction away from the fixed plate.

[0012] Furthermore, the diameter of the first tube placement groove is 0.2-0.3 cm, the diameter of the second tube placement groove is 0.3-0.4 cm, and the diameter of the third tube placement groove is 0.4-0.5 cm.

[0013] Furthermore, the cover is made of aluminum alloy, and the main frame is made of aluminum alloy.

[0014] Instructions for use: This device consists of a main frame, three cover plates, and corresponding bolts. The main frame has three independent semi-circular grooves of different radii for placing tubular ordered porous films to accommodate glass tubes of different diameters. Each groove on the main frame is equipped with a cover plate, which also has a semi-circular groove of the same size. Each groove on the main frame has four M4 screw holes around its perimeter for tightening the main frame, glass tube, and cover plate together with bolts. A square opening is located in the center of the grooves on the main frame and cover plates. When installed in the microscope optical path, light can travel from the opening on the main frame to the glass tube carrying the ordered porous film and simultaneously return the reflected interference signal along the same path. The opening on the cover plates allows for visual adjustment of the light spot position and focus, and observation of the filling condition within the tube.

[0015] Beneficial effects: Compared with the prior art, this utility model has the following characteristics:

[0016] 1. Ordered porous films can be stably fixed on biosensing platforms and can be used for biosensing research based on optical interferometry systems;

[0017] 2. The main frame made of aluminum alloy has a certain degree of hollowing and thinning design, which minimizes the weight redundancy while ensuring that it can be placed stably in the microscope optical path.

[0018] 3. The main frame has grooves of different sizes, which can hold up to three glass tubes of different diameters at the same time, and is equipped with independent covers for the corresponding grooves.

[0019] 4. The groove on the independent cover plate matches the groove on the main frame to keep the glass tube in a horizontal position;

[0020] 5. The main frame is equipped with screw holes, and bolts can be used to fasten the cover plate, the main frame and the glass tube together;

[0021] 6. The openings on the cover plate and main frame can be used to visually observe the relative position of the glass tube and the microscope light source, to rotate or translate at any time to adjust the position of the light spot on the glass tube, and to visually observe the filling condition inside the tube, etc.

[0022] 7. A gasket is attached to the groove for holding the glass tube to secure it. Attached Figure Description

[0023] Figure 1 Schematic diagram of the utility model;

[0024] Figure 2 A schematic diagram illustrating the use of the utility model;

[0025] Figure 3 Schematic diagram of the main frame 1 of the utility model;

[0026] Figure 4 A schematic diagram of the structure of the utility model cover plate 2. Detailed Implementation

[0027] like Figures 1-4In the microscope optical path, the main frame 1 and cover plate 2 of the fixing device for the tubular ordered porous film are fixedly connected by bolts 5. The main frame 1 is made of aluminum alloy, and the cover plate 2 is also made of aluminum alloy. The main frame 1 includes a fixing plate 11 and contact feet 17. The fixing plate 11 has three semi-circular grooves, from left to right: the first tube placement groove 12, the second tube placement groove 13, and the third tube placement groove 14, with diameters of 0.5cm, 0.4cm, and 0.3cm, respectively, used to match glass tubes with different diameters. The fixing plate 11 has four L-shaped contact feet 17 at its four corners for contacting and placing on the microscope stage. Each individual cover plate 2 has a semi-circular upper tube placement groove 21. The first tube placement groove 12, the second tube placement groove 13, the third tube placement groove 14, and the upper tube placement groove 21 contain a 0.3mm thick pad made of elastic material. The upper and lower grooves are aligned to effectively fix glass tubes 3 of different diameters each time. The thickness of the contact foot 17 is greater near the fixed plate 11 (8mm) than the thickness at the end (3.5mm).

[0028] The fixing plate 11 has four screw holes 15 and light-transmitting windows 16 at the first tube placement slot 12, the second tube placement slot 13, and the third tube placement slot 14, respectively. When installed in the microscope optical path, the light emitted by the halogen lamp source can reach the glass tube 3 carrying the ordered porous film through the square light-transmitting window 16 with a side length of 8mm on the main frame 1, and simultaneously return the reflected interference signal along the original path. The cover plate 2 has a square viewing window 23 with a side length of 9mm at its center, and straight holes 22 at its four corners. The diameter of the straight holes 22 is the same as that of the screw holes 15, which is 4mm, for passing through bolts 5, thereby fixing the main frame 1 and the cover plate 2 together. Bolts 5 are preferably bolts 5. The viewing window 23 can be used to visually adjust the position and focus of the light spot and observe the filling condition inside the tube.

[0029] When it is necessary to fix the glass tube 3 containing the tubular ordered porous membrane, place it on the first tube placement groove 12, the second tube placement groove 13, or the third tube placement groove 14 with similar diameters, and align the exposed part of the glass tube 3 with the upper tube placement groove 21 of the cover plate 2. The gasket 4 is elastic and can further tighten the glass tube 3. Pass four metric M4 bolts 5 through the screw holes and tighten them to fix the glass tube 3 containing the tubular ordered porous membrane. When the experiment is over, the bolts 5 can be removed to separate the cover plate 2, the glass tube 3, and the main frame 1.

Claims

1. A device for immobilizing tubular ordered porous membranes in a micro-optical circuit, characterized in that: The utility model relates to a glass tube fixing device, including main frame (1), cover piece (2), the main frame (1) includes fixed plate (11), the fixed plate (11) is set up first pipe setting groove (12) gradually reducing diameter, second pipe setting groove (13) and third pipe setting groove (14) in interval, the cover piece (2) is set up on the upper pipe setting groove (21), the upper pipe setting groove (21) can be with first pipe setting groove (12), second pipe setting groove (13) or third pipe setting groove (14) alignment, to form the cavity for fixing the glass tube (3) of being equipped with tubular ordered porous membrane, the inner wall of upper pipe setting groove (21), first pipe setting groove (12), second pipe setting groove (13), third pipe setting groove (14) all is provided with gasket (4).

2. A device for immobilizing tubular ordered porous membranes in a light path of a microscope according to claim 1, characterized in that: The fixed plate (11) is set up screw hole no. (15) near first pipe setting groove (12), second pipe setting groove (13), third pipe setting groove (14), and the cover piece (2) is set up straight hole (22) and visual window (23) corresponding with screw hole no. (15).

3. The device of claim 1, wherein: The fixed plate (11) is set up light transmission window (16) at first pipe setting groove (12), second pipe setting groove (13), third pipe setting groove (14).

4. The device of claim 1, wherein: The main frame (1), cover piece (2) are fixedly connected through bolt (5).

5. A device for holding a tubular ordered porous membrane in a light path of a microscope according to claim 4, characterized in that: The bolt (5) is M4 bolt.

6. The device of claim 1, wherein: The main frame (1) still includes several contact foot plates (17), and the contact foot plates (17) are arranged in the circumference of the fixed plate (11).

7. A device for holding a tubular ordered porous membrane in a light path of a microscope according to claim 6, characterized in that: The contact foot plate (17) is L type.

8. The device of claim 6, wherein: The thickness of the contact foot plate (17) gradually reduces along the direction away from the fixed plate (11).

9. The device of claim 1, wherein: The diameter of the first pipe setting groove (12) is 0.2-0.3 cm, the diameter of the second pipe setting groove (13) is 0.3-0.4 cm, and the diameter of the third pipe setting groove (14) is 0.4-0.5 cm.

10. The device of claim 1, wherein: The cover piece (2) is an aluminum alloy cover piece, and the main frame (1) is an aluminum alloy main frame.

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