Auxiliary activation device for frozen embryo

By designing an auxiliary activation device that includes a box, an embryo placement container, a turntable placement mechanism, and a lifting and grasping mechanism, rapid multi-stage thawing of frozen embryos was achieved, improving thawing efficiency and survival rate while ensuring operational safety.

CN224015684UActive Publication Date: 2026-03-20MULTIPOTENT STEM CELL REGENERATIVE MEDICINE TECH (GUANGZHOU) CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-03-17
Publication Date
2026-03-20

AI Technical Summary

Technical Problem

Existing frozen embryo thawing devices have low thawing efficiency and low survival rate.

Method used

An auxiliary activation device is adopted, which includes a box, an embryo placement container, a turntable placement mechanism, a lifting and grasping mechanism, and a thawing solution placement container. The lifting and grasping mechanism quickly and stably transfers the embryo placement container to different thawing solution placement containers under the rotation traction of the turntable placement mechanism, realizing multi-stage auxiliary activation operation.

Benefits of technology

This improves thawing efficiency, avoids embryo damage, and enhances the safety and efficiency of activation.

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Abstract

The utility model belongs to the technical field of medical equipment, and particularly relates to an auxiliary activation device for frozen embryos, which comprises a box body, an embryo placing container, a turntable placing mechanism, a lifting grabbing mechanism and at least one solution placing container for unfreezing, an operation inner cavity is formed in the box body; the turntable placing mechanism is connected to the inner bottom of the operation inner cavity; the container for placing the solution required for unfreezing is connected to the turntable placing mechanism; the embryo placing container is connected to the turntable placing mechanism; the lifting grabbing mechanism is arranged in the operation inner cavity. And the movable end of the lifting grabbing mechanism can move to the embryo placing container and / or the unfreezing solution placing container. According to the utility model, the auxiliary activation efficiency can be improved, and the embryo to be unfrozen and activated can be prevented from being damaged.
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Description

TECHNICAL FIELD

[0001] The utility model belongs to the technical field of medical equipment, especially relates to a frozen embryo's auxiliary activation device. BACKGROUND

[0002] The frozen embryo is a method that the embryo and the freezing liquid are loaded into the macaroni tube, the embryo can be still down through slow (the embryo of 2-3 days) and fast (the blastocyst of 5-6 days) two kinds of cooling ways, and is stored in the liquid nitrogen environment of minus 196 DEG C, is implanted into the uterine cavity after the natural cycle or the artificial cycle thawing, and the chance of conception is increased, which is the only mature method for saving the reproductive function so far.

[0003] However, most of the existing frozen embryo thawing devices are embryo static natural recovery, the thawing efficiency of which is too low, and the survival rate of the frozen embryo recovery is low. UTILITY MODEL CONTENT

[0004] The utility model discloses a frozen embryo's auxiliary activation device, which can solve the technical problem of low thawing efficiency of the prior art.

[0005] In order to achieve the above object, the utility model adopts the following technical scheme:

[0006] A frozen embryo's auxiliary activation device, which comprises a box body, an embryo placing container, a turntable placing mechanism, a lifting and grabbing mechanism and at least one thawing solution placing container.

[0007] Preferably, the inside of the embryo placing container is provided with a first storage cavity, and the inner side wall of the embryo placing container is provided with at least one flow guide through hole.

[0008] Preferably, the top of the embryo placing container towards the lifting and grabbing mechanism is provided with a metal piece, and the lifting and grabbing mechanism is adsorbedly connected with the metal piece.

[0009] Preferably, the inside of the thawing solution placing container is provided with a second storage cavity.

[0010] Preferably, the rotating disc placing mechanism comprises a rotating disc body, a connecting shaft and a rotating driving motor; the rotating driving motor is connected to the inner bottom of the operation inner cavity and connected with one end of the connecting shaft; the other end of the connecting shaft is connected with the bottom of the rotating disc body; the embryo placing container and all the thawing solution placing containers are respectively connected to the top of the rotating disc body.

[0011] Preferably, the rotating disc body is provided with a first mounting groove; the embryo placing container is connected to the inside of the first mounting groove.

[0012] Preferably, the rotating disc body is provided with a second mounting groove; the thawing solution placing container is connected to the inside of the second mounting groove.

[0013] Preferably, the lifting and grabbing mechanism comprises a placing shell, a sliding driving motor, a screw rod, a sliding support, an electromagnet and a connecting frame; the placing shell is connected to the inner side wall of the box body; the sliding driving motor is connected to the placing shell and connected with one end of the screw rod; the other end of the screw rod is connected to the placing shell; the sliding support is slidably connected to the outer surface of the screw rod; the outer top surface of the sliding support of the connecting frame; the end of the connecting frame is connected to the electromagnet; the electromagnet can be adsorbed and connected with the embryo placing container.

[0014] Preferably, the inner top of the operation inner cavity is provided with at least one illumination light source.

[0015] The beneficial effects of the utility model lie in that the embryo placing container containing the activated embryo to be thawed is lifted by the lifting and grabbing mechanism, and under the rotating traction of the rotating disc placing mechanism at the bottom, the embryo placing container containing the activated embryo to be thawed can be quickly and stably transferred to the inside of different thawing solution placing containers 4, so that the auxiliary activation operation in different stages is realized, the auxiliary activation efficiency can be improved, and the activated embryo to be thawed can be prevented from being damaged, and the safety of activation is improved. BRIEF DESCRIPTION OF DRAWINGS

[0016] The features, advantages, and technical effects of the exemplary embodiments of the utility model will be described below with reference to the accompanying drawings. Figures 1-5

[0017] Figure 1 It is a structural schematic view of the auxiliary activation device for the frozen embryo according to an embodiment of the utility model;

[0018] Figure 2 It is a structural schematic view of the embryo placing container of the auxiliary activation device for the frozen embryo according to an embodiment of the utility model;

[0019] ​Figure 3 This is a schematic diagram of the structure of the solution placement container for the thawing of a frozen embryo auxiliary activation device according to an embodiment of the present invention.

[0020] Figure 4 This is a schematic diagram of the turntable placement mechanism of an auxiliary activation device for frozen embryos according to an embodiment of the present invention;

[0021] Figure 5 This is a schematic diagram of the lifting and gripping mechanism of an auxiliary activation device for frozen embryos according to an embodiment of the present invention;

[0022] Figure 6 This is a partial structural diagram of the lifting and gripping mechanism of an auxiliary activation device for frozen embryos according to an embodiment of the present invention.

[0023] In the diagram: 1-Box body; 11-Operating cavity; 2-Embryo placement container; 21-First storage cavity; 22-Guide hole; 23-First limiting protrusion; 24-First limiting groove; 25-Metal part; 3-Turntable placement mechanism; 31-Turntable body; 32-Connecting shaft; 33-Rotation drive motor; 34-First mounting groove; 341-First abutting protrusion; 35-Second mounting groove; 351-Second abutting protrusion; 4-Thawing solution placement container; 41-Second storage cavity; 42-Second limiting protrusion; 43-Second limiting groove; 5-Lifting gripping mechanism; 51-Placement shell; 52-Sliding drive motor; 53-Screw; 54-Sliding support; 55-Connecting frame; 551-Connecting plate; 552-Folding rod; 553-Connecting block; 56-Electromagnet; 6-Irradiation light source. Detailed Implementation

[0024] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application pertains; the terminology used herein is for the purpose of describing particular embodiments only and is not intended to limit the application; the terms “comprising” and “having”, and any variations thereof, in the specification, claims, and foregoing description of the drawings are intended to cover non-exclusive inclusion.

[0025] In the description of the embodiments of this application, technical terms such as "first" and "second" are used only to distinguish different objects and should not be construed as indicating or implying relative importance or implicitly specifying the number, specific order, or primary and secondary relationship of the indicated technical features. In the description of the embodiments of this application, "multiple" means two or more, unless otherwise explicitly defined.

[0026] Reference to an "embodiment" in this document means that a particular feature, structure, or characteristic described in connection with the embodiment can be included in at least one embodiment of the application. The appearances of the phrase in various places in the specification are not necessarily all referring to the same embodiment, nor are they necessarily mutually exclusive of one another. It is expressly understood that the embodiments described herein are merely examples from among a great variety of embodiments that can be made by a person of ordinary skill in the art.

[0027] In the description of the embodiments of the application, the term "and / or" is merely an association relationship of the associated objects, which means that there can be three relationships, for example, A and / or B, which can mean that A exists alone, A and B exist together, and multiple cases exist alone. In addition, the character " / " in this paper generally represents an "or" relationship between the front and rear associated objects.

[0028] In the description of the embodiments of the application, unless otherwise explicitly specified and limited, the technical terms "mounting", "connection", "connection", "fixing" and the like should be understood in a broad sense, for example, it can be fixedly connected, or it can be detachably connected, or it can be integrated; it can be mechanical connection, or it can be electrical connection; it can be directly connected, or it can be indirectly connected through an intermediate medium; it can be the internal communication of two elements or the interaction relationship between two elements. For those skilled in the art, the specific meaning of the above terms in the embodiments of the application can be understood according to the specific circumstances.

[0029] The following will be described in detail in combination with the accompanying drawings Figures 1-6 The utility model will be described in further detail, but not as the limitation of the utility model.

[0030] As Figure 1 As shown in the utility model embodiment, the auxiliary activation device of frozen embryo; Including box 1, embryo placing container 2, carousel placing mechanism 3, lifting and grabbing mechanism 5 and at least one thawing solution placing container 4 required, the box 1 is equipped with operation inner chamber 11, the carousel placing mechanism 3 is connected in the inner bottom of operation inner chamber 11, all thawing solution placing container 4 required is connected on carousel placing mechanism 3, embryo placing container 2 is connected on carousel placing mechanism 3, lifting and grabbing mechanism 5 is arranged in the inside of operation inner chamber 11, and the movable end of lifting and grabbing mechanism 5 can move to embryo placing container 2 and / or thawing solution placing container 4 required.

[0031] The technical solution of this utility model uses a lifting and gripping mechanism to lift the embryo placement container containing the embryos to be thawed and activated. Under the rotational traction of the turntable placement mechanism at the bottom, the embryo placement container containing the embryos to be thawed and activated can be quickly and stably transferred to the interior of different thawing solution placement containers 4, thereby realizing auxiliary activation operations at different stages, which can improve the auxiliary activation efficiency, avoid damage to the embryos to be thawed and activated, and improve the safety of activation.

[0032] Specifically, in some implementations, such as Figure 1 and 2 As shown, the embryo placement container 2 has a first storage cavity 21 inside; and the inner sidewall of the embryo placement container 2 has at least one guide hole 22; the two ends of the guide hole 22 are respectively connected to the first storage cavity 21 and the outside of the embryo placement container 2. That is to say, by storing the embryos to be thawed and activated in the first storage cavity 21 and guiding the external thawing liquid into the interior of the first storage cavity 21 through the guide hole 22, the activation speed and efficiency are improved, and the stability and safety of the transfer and placement of the embryos to be thawed and activated are ensured.

[0033] Specifically, in some implementations, such as Figure 1 and 2 As shown, the embryo placement container 2 has a metal component 25 on its top facing the lifting and grasping mechanism 5; the lifting and grasping mechanism 5 is adsorbed and connected to the metal component 24. This structure uses the adsorption of the metal component 24 to drive the embryo placement container 2 to move up and down in an orderly manner, thereby improving the convenience of transfer and ensuring the stability and safety of transfer.

[0034] Specifically, in some implementations, such as Figure 1 As shown, the solution placement container 4 for thawing includes a thawing liquid placement container, a diluent placement container, and a cleaning liquid placement container arranged sequentially along the upper surface of the turntable placement mechanism 3; and each of the thawing liquid placement container, the diluent placement container, and the cleaning liquid placement container is provided with a second storage cavity 41; the second storage cavity 41 contains thawing liquid, diluent, or cleaning liquid.

[0035] Specifically, in some implementations, such as Figure 1 and 4As shown, the rotating disc placing mechanism 3 comprises a rotating disc body 31, a connecting shaft 32 and a rotating driving motor 33; the rotating driving motor 33 is connected to the inner bottom of the operation inner cavity 11 and connected to one end of the connecting shaft 32; the other end of the connecting shaft 32 is connected to the bottom of the rotating disc body 31; the embryo placing container 2 and all the thawing solution placing containers 4 are respectively connected to the top of the rotating disc body 31. This structure is driven by the rotating driving motor 33 to realize the movement of the embryo placing container 2 to the lower side of the lifting and grabbing mechanism 5, so as to realize the grabbing movement of the embryo placing container 2, and then drive the rotating disc body 31 and the thawing solution placing container 4 to rotate; then drive the lifting and grabbing mechanism 5 to transfer the embryo placing container 2 to the inside of the thawing solution placing container 4, so as to realize the rapid auxiliary activation thawing effect.

[0036] In some embodiments, as shown in Figure 4 As shown, the rotating disc body 31 is provided with a first mounting groove 34; the embryo placing container 2 is connected to the inside of the first mounting groove 34. This structure improves the assembly stability of the embryo placing container 2 to ensure the safety of the transfer. Further, as shown in Figure 2 and 4 As shown, the inside of the first mounting groove 34 is provided with a first abutting protrusion 341; and a first gap is provided between the outer side wall of the first abutting protrusion 341 and the inner side wall of the first mounting groove 34; the bottom of the embryo placing container 2 is provided with at least two first limiting protrusions 23; a first limiting groove 24 is provided between the first limiting protrusions 23; the first abutting protrusion 341 is connected to the inside of the first limiting groove 24; and the first limiting protrusions 23 are connected to the first gap. This structure can further improve the assembly stability of the embryo placing container 2 to ensure the safety of the transfer.

[0037] In some embodiments, as shown in Figure 4 As shown, the rotating disc body 31 is provided with a second mounting groove 35; the thawing solution placing container 4 is connected to the inside of the second mounting groove 35. This structure can improve the assembly stability of the thawing solution placing container 4 to ensure the safety of the transfer. Further, as shown in Figure 3 and 4As shown in the figure, the second installation slot 35 is internally provided with a second abutting protrusion 351; and a second gap is provided between the outer sidewall of the second abutting protrusion 351 and the inner sidewall of the second installation slot 35; the bottom of the thawing solution placement container 4 is provided with at least two second limiting protrusions 42; a second limiting groove 43 is provided between the second limiting protrusions 42; the second abutting protrusion 351 is connected to the inside of the second limiting groove 43; and the second limiting protrusion 42 is connected to the second gap. This structure can further improve the assembly stability of the thawing solution placement container 4 to ensure the safety of the transfer.

[0038] Specifically, in some embodiments, as shown in Figure 1 and 5 As shown in the figure, the lifting and grabbing mechanism 5 includes a placement housing 51, a sliding drive motor 52, a screw rod 53, a sliding support 54, an electromagnet 56, and a connecting frame 55; the placement housing 51 is connected to the inner sidewall of the box body 1; the sliding drive motor 52 is connected to the placement housing 51 and connected to one end of the screw rod 53; the other end of the screw rod 53 is connected to the placement housing 51; the sliding support 54 is slidably connected to the outer surface of the screw rod 53; the outer top surface of the sliding support 54 of the connecting frame 55; the end of the connecting frame 55 is connected to the electromagnet 56; and the electromagnet 56 can be adsorbed and connected to the embryo placement container 2 (metal part 25). As shown in Figure 5 and 6 As shown in the figure, the outer sidewall of the sliding support 54 is provided with a positioning protrusion; the positioning protrusion is limited to slide in the installation gap in the inside of the placement housing 51 to avoid the sliding support 54 from rotating and the like. Further, as shown in Figure 5 and 6 As shown in the figure, the connecting frame 55 includes a connecting plate 551, a folding rod 552, and a connecting block 553; the connecting plate 551 is connected to the sliding support 54; one end of the folding rod 552 is connected to the connecting plate 551; the other end of the folding rod 552 is connected to the connecting block 553; and the electromagnet 56 is connected to the connecting block 553. Still further, the number of the sliding supports 54 is two; and the cross section of the folding rod 552 is F-shaped.

[0039] Specifically, in some embodiments, as shown in Figure 1 As shown in the figure, the inner top of the operation inner cavity 11 is provided with at least one illumination light source 6. The wavelength range of the illumination light source 6 is 500-10000 nm, and the power density range of the illumination light source 6 is 0.01-30 mw / cm 2Furthermore, the illumination light source 6 is a line light source, which is arranged parallel to the inner wall surface of the housing; or, the light source is a surface light source; to improve the survival rate of frozen embryos after thawing, thereby increasing the embryo implantation rate.

[0040] Furthermore, it should be understood that although this specification describes embodiments, not every embodiment contains only one independent technical solution. This narrative style of the specification is merely for clarity. Those skilled in the art should regard the specification as a whole, and the technical solutions in each embodiment can also be appropriately combined to form other embodiments that can be understood by those skilled in the art.

[0041] Based on the disclosure and teachings of the above specification, those skilled in the art can make changes and modifications to the above embodiments. Therefore, this utility model is not limited to the specific embodiments described above, and any obvious improvements, substitutions, or modifications made by those skilled in the art based on this utility model are within the protection scope of this utility model. Furthermore, although some specific terms are used in this specification, these terms are only for convenience of explanation and do not constitute any limitation on this utility model.

Claims

1. An auxiliary activation device for frozen embryos, characterized in that: The device includes a housing, an embryo placement container, a turntable placement mechanism, a lifting and grasping mechanism, and at least one thawing solution placement container. The housing has an operating cavity. The turntable placement mechanism is connected to the bottom of the operating cavity. The thawing solution placement container is connected to the turntable placement mechanism. The embryo placement container is connected to the turntable placement mechanism. The lifting and grasping mechanism is located inside the operating cavity, and its movable end is capable of moving to the embryo placement container and / or the thawing solution placement container.

2. The auxiliary activation device for frozen embryos according to claim 1, characterized in that: The embryo placement container has a first storage cavity inside; and the inner wall of the embryo placement container has at least one guide hole; the two ends of the guide hole are respectively connected to the first storage cavity and the outside of the embryo placement container.

3. The auxiliary activation device for frozen embryos according to claim 2, characterized in that: The embryo placement container is provided with a metal part at the top facing the lifting and gripping mechanism; the lifting and gripping mechanism is adsorbed and connected to the metal part.

4. The auxiliary activation device for frozen embryos according to claim 1, characterized in that: The container for storing the solution required for thawing has a second storage chamber inside.

5. The auxiliary activation device for frozen embryos according to claim 1, characterized in that: The turntable placement mechanism includes a turntable body, a connecting shaft, and a rotation drive motor; the rotation drive motor is connected to the bottom of the inner cavity of the operating chamber and to one end of the connecting shaft; the other end of the connecting shaft is connected to the bottom of the turntable body; the embryo placement container and all the thawing solution placement containers are respectively connected to the top of the turntable body.

6. The auxiliary activation device for frozen embryos according to claim 5, characterized in that: The turntable is provided with a first mounting slot, and the embryo placement container is connected to the inside of the first mounting slot.

7. The auxiliary activation device for frozen embryos according to claim 5 or 6, characterized in that: The turntable is provided with a second mounting groove; the container for placing the thawing solution is connected to the inside of the second mounting groove.

8. The auxiliary activation device for frozen embryos according to claim 1, characterized in that: The lifting and gripping mechanism includes a placement housing, a sliding drive motor, a screw, a sliding support, an electromagnet, and a connecting frame. The placement housing is connected to the inner wall of the box. The sliding drive motor is connected to the placement housing and to one end of the screw. The other end of the screw is connected to the placement housing. The sliding support is slidably connected to the outer surface of the screw. The connecting frame is attached to the outer top surface of the sliding support. The end of the connecting frame is connected to the electromagnet. The electromagnet can be attracted and connected to the embryo placement container.

9. The auxiliary activation device for frozen embryos according to claim 1, characterized in that: At least one illumination light source is provided at the top of the inner cavity of the operating chamber.