Closestool, urinalysis instrument, detection equipment and kit thereof
By designing detachable reagent kits and testing equipment, the problem of overall equipment waste after the reagents of home urine analyzers are solved, enabling rapid replacement of reagent kits and increasing the durability of the equipment, while simplifying the operation process.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-03-26
- Publication Date
- 2026-03-24
AI Technical Summary
Existing home urine analyzers cannot be replaced once the reagents are used up, resulting in material waste and inconvenient replacement procedures for operators.
Design a detachable reagent kit and detection device. The reagent kit is a flat plate with multiple reagent chambers and flow channels. Combined with the flow channel plate and rotor, the reagent kit can be replaced and the device can be detached and assembled. The durability of the drive components and pump can be used to extend the life of the device.
It enables rapid reagent kit replacement, reduces material waste, extends equipment lifespan, simplifies operation procedures, and lowers maintenance costs.
Smart Images

Figure CN224035423U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model relates to the technical field of urine test instrument, especially a closestool, urine test instrument, detection equipment and its reagent box. BACKGROUND
[0002] With the growth of human life, the importance of health care and maintenance has been paid more and more attention. Urine can reflect a person's health condition to a certain extent, and through quantitative analysis of urine composition, diseases such as pancreas and kidney can be understood. Urine analysis is an important indicator for detecting the physical condition of a person, which can usually detect pH, protein, occult blood, specific gravity, glucose, ketone body, urobilin, nitrate, leukocyte, bilirubin and vitamin C, and reflect a series of indicators of the body. The usual urine test is carried out in the hospital. Due to the shortage of medical resources, the examinee often has to queue up for registration, see a doctor, pay fees, take urine, wait for batch urine test, and then queue up to get the results, which is time-consuming and laborious.
[0003] At present, a urine test instrument for home use appears in the market. When the reagent is used up, the whole urine test instrument is basically discarded, but the pump and driving part inside still have a long service life, causing material waste. However, if only the reagent is replaced, the replacement process is not easy for the operator, so a small replaceable part is needed, which contains a small reagent box inside for overall replacement. UTILITY MODEL CONTENT
[0004] The utility model aims at providing a closestool, urine test instrument, detection equipment and its reagent box to solve the problems of the prior art.
[0005] To solve the above technical problems, the embodiment of the utility model provides a reagent box, which is flat and plate-shaped and is provided with a plurality of reagent cavities and a plurality of flow channel holes, one end of each of the plurality of reagent cavities is in communication with one of the plurality of flow channel holes.
[0006] In one embodiment, the plurality of flow channel holes are arranged at intervals around a horizontal axis.
[0007] In one embodiment, the plurality of reagent cavities extend in a vertical direction and are arranged in a first direction, and the bottom end of each of the plurality of reagent cavities is in communication with one of the plurality of flow channel holes.
[0008] In one embodiment, the reagent box has a front side and a rear side arranged oppositely;
[0009] The bottom wall of each of the plurality of reagent cavities comprises an inclined surface and a vertical surface, the height of the inclined surface gradually decreases from the rear to the front;
[0010] The top surface of the vertical surface is connected with the front end of the inclined surface.
[0011] The plurality of flow channel holes are recessed from the rear side of the kit to the vertical surface.
[0012] In one embodiment, the kit further comprises a plurality of sealing grooves, the plurality of sealing grooves being recessed from the rear side of the kit to the vertical surface.
[0013] The plurality of flow channel holes are recessed from the inner wall of the plurality of sealing grooves to the vertical surface.
[0014] In one embodiment, the reagent cavity is open towards the top end of the kit.
[0015] The present application also relates to a detection device, comprising:
[0016] a first housing,
[0017] the kit as described above;
[0018] a flow channel plate located in the first housing and comprising:
[0019] a central hole penetrating the flow channel plate and located on a horizontal axis;
[0020] a common flow channel, the inner end of which is in communication with the central hole;
[0021] a plurality of circumferential holes, the plurality of circumferential holes being arranged at intervals around the central hole and located on the same circumference;
[0022] a sample flow channel, the inner end of which is in communication with one of the circumferential holes, and the outer end of which is in communication with a collection cavity located outside the first housing; and
[0023] a plurality of reagent flow channels, the plurality of reagent flow channels being in communication with the plurality of circumferential holes and the plurality of flow channel holes, respectively; a detection flow channel, the inner end of which is in communication with one of the circumferential holes, and the outer end of which is in communication with the collection cavity;
[0024] a rotor, the rotor being rotatably installed in the first housing and comprising a transfer channel, the inner end of the transfer channel being in communication with the central hole, and the outer end of the transfer channel being operatively in communication with any one of the circumferential holes as the rotor rotates.
[0025] In one embodiment, the detection device further comprises a detection plate, a portion of the detection plate being located in the first housing and comprising a detection cavity, the detection cavity being in communication with the common flow channel.
[0026] The present application also relates to a urine test instrument, comprising:
[0027] A second housing, which is detachably connected with the first housing; and
[0028] The detection device as described above;
[0029] A driving member, which is located in the second housing and detachably connected with the rotor, and is operable to drive the rotor to rotate;
[0030] A collector, which is provided with a collecting cavity, and the collecting cavity is communicated with the sample flow channel;
[0031] A pump, which is located in the second housing and connected with the common flow channel through a driving pipeline;
[0032] A detection mechanism, which comprises a detector and a detection plate, and the detection plate is provided with a detection cavity, and the detection cavity is communicated with the detection flow channel; and the detector is used for detecting the liquid in the detection cavity.
[0033] The present application also relates to a toilet, which comprises the urine detection instrument as described above. BRIEF DESCRIPTION OF DRAWINGS
[0034] Figure 1 It is a perspective view of the urine detection instrument of one embodiment of the present application.
[0035] Figure 2 、 Figure 3 、 Figure 4 、 Figure 5 、 Figure 6 、 Figure 7 and Figure 8 are respectively Figure 1 the exploded view of the urine detection instrument of the embodiment shown in Fig.
[0036] Figure 9 is Figures 1-8 the perspective view of the locking member in the embodiment shown in Fig.
[0037] Figure 10 and Figure 11 are respectively Figure 2 the perspective view of the kit in the embodiment shown in Fig.
[0038] Figure 12 and Figure 13 are respectively Figure 2 the perspective view of the cover plate in the embodiment shown in Fig.
[0039] Figure 14 is Figure 2 the perspective view of the flow channel plate in the embodiment shown in Fig.
[0040] Figure 15 is Figure 14 the partial enlarged view of the A area of the flow channel plate.
[0041] Figure 16 is Figure 14 a partial enlarged view of the B area of the flow channel plate.
[0042] Figure 17 is Figure 2 a perspective view of the flow channel plate in the embodiment shown in
[0043] Figure 18 is Figure 4 and Figure 5 a perspective view of the first adapter of the embodiment shown in
[0044] Figure 19 is Figure 4 and Figure 5 an assembly view of the kit, the flow channel plate, the cover plate, the first adapter, the rotor and the protective cover in the embodiment shown in
[0045] Figure 20 is Figure 1 an exploded view of the first housing in the embodiment shown in
[0046] Figure 21 is Figure 2 a perspective view of the detection plate in the embodiment shown in
[0047] Figure 22 and Figure 23 is Figure 2 an exploded view of the protective cover, the rotor, the compression spring and the convex ring in the embodiment shown in
[0048] Figure 24 is Figure 1 an exploded view of the second housing, the peristaltic pump, the plunger pump and the motor in the embodiment shown in
[0049] Figure 25 is a perspective view of the collector of one embodiment of the present utility model.
[0050] Figure 26 and Figure 27 are respectively Figure 25 an exploded view of the collector of the embodiment shown in
[0051] Figure 28 is a perspective view of the collector of another embodiment of the present utility model.
[0052] Figure 29 and Figure 30 are respectively Figure 28 an exploded view of the collector of the embodiment shown in
[0053] Figure 31 is a flow chart of the operation method of the urine test instrument of one embodiment of the present utility model.
[0054] Figure 32It is the liquid path diagram of the urine test instrument of one embodiment of the utility model. DETAILED DESCRIPTION
[0055] In order to make the purpose, technical scheme and advantages of the utility model more clear, the various embodiments of the utility model will be described in detail below with reference to the drawings. However, those skilled in the art can understand that, in the various embodiments of the utility model, many technical details are proposed in order to make the reader better understand the present application. However, even if there is no such technical detail and various changes and modifications based on the following embodiments, the technical scheme claimed by each claim of the present application can be realized.
[0056] Unless the context requires otherwise, throughout the specification and claims which follow, the word "comprise" and variations thereof such as "comprises" and "comprising" are to be construed in an open, inclusive sense, that is as "including, but not limited to."
[0057] The various embodiments of the utility model will be described in detail below with reference to the drawings, so that the purpose, characteristics and advantages of the utility model can be more clearly understood. It should be understood that the embodiments shown in the drawings are not a limitation on the scope of the utility model, but only to illustrate the essential spirit of the technical scheme of the utility model.
[0058] The reference to "one embodiment" or "an embodiment" in the entire specification means that the particular feature, structure or characteristic described in connection with the embodiment is included in at least one embodiment. Therefore, the occurrence of "in one embodiment" or "in an embodiment" in various places in the specification does not necessarily refer to the same embodiment. In addition, the particular features, structures or characteristics can be combined in any way in one or more embodiments.
[0059] As used in the specification and the appended claims, the singular forms "a" and "the" include plural referents unless the context clearly dictates otherwise. It should be noted that the term "or" is generally employed in its sense including "and / or" unless the context clearly dictates otherwise.
[0060] In the following description, in order to clearly show the structure and working mode of the utility model, many directional words will be used for description, but the words "front", "back", "left", "right", "outer", "inner", "outward", "inward", "up", "down" and the like should be understood as convenient language, and should not be understood as limiting words.
[0061] The utility model relates to a kind of urine test instrument 100, such as Figures 1-4As shown, the urine test instrument 100 comprises a shell 1, a collector 4, a reagent box 2 located in the shell 1, a rotary valve, a pump and a detection mechanism, wherein the rotary valve comprises a microfluidic chip, a rotor 6 and a driving member 93, wherein the reagent box 2 is used for containing a plurality of reagents, the collector 4 is provided with a collection cavity, the collection cavity comprises a sample collection cavity 411 and a water collection cavity 412, the sample collection cavity 411 is used for collecting a sample, and the water collection cavity 412 is used for storing water. The flow channel plate 3 is used for providing a plurality of flow channels for the convergence of reagents and samples. As shown in the figure, Figure 5 The detection mechanism comprises a detector and a detection plate 5, wherein the detection plate 5 is provided with a detection cavity, the detection cavity is used for receiving the sample and the reagent of the flow channel plate 3, and the detection cavity is used for detecting the sample in the detection cavity. The rotor 6 is used to cooperate with the flow channel plate 3 to facilitate the collection of the sample and the reagent, and to push the sample and the reagent into the detection mechanism for detection. Figures 22-24 The driving member 93 is connected with the rotor 6 and is used to drive the rotor 6 to rotate.
[0062] Specifically, as shown in the figure, Figure 1 The shell 1 comprises a first shell body 11 and a second shell body 12, the rear side of the first shell body 11 and the front side of the second shell body 12 are detachably connected, the "front side" and the "front end" of the urine test instrument 100 are the side of the first shell body 11 away from the second shell body 12, and the "rear side" or the "rear end" is the side of the second shell body 12 away from the first shell body 11. The reagent box 2, the rotor 6 and the flow channel plate 3 are located in the first shell body 11, and the pump and the driving member 93 are located in the second shell body 12, and the driving member 93 and the rotor 6 are detachably connected. The driving member 93 and the pump in the second shell body 12 are durable components and have a long service life, and the first shell body 11 and the reagent box 2, the rotor 6 and the flow channel plate 3 in the first shell body 11 are combined into a detection device, which is consumable equipment. After a period of use, the reagents in the reagent box 2 are consumed, the detection device can be replaced, which can ensure that the materials are fully used and reduce waste.
[0063] In a specific embodiment, as shown in the figure, Figures 4-5 The first shell body 11 comprises a first front cover 111 and a first rear cover 112, the first front cover 111 and the first rear cover 112 are connected by clamping or bolts, and form a containing space. As shown in the figure, the first front cover 111 comprises a first front connecting ring 1111 and a first front cover plate 1112 connected with the front end of the first front connecting ring 1111. And the first rear cover 112 comprises a first rear connecting ring 1121 and a first rear cover plate 1122 connected with the rear end of the first rear connecting ring 1121, the rear end of the first front connecting ring 1111 and the front end of the first rear connecting ring 1121 are opposite to each other and clamped, and are further connected by bolts, and the specific connection mode is not limited.
[0064] As shown in the figure, Figure 4As shown, the second housing 12 includes a second front cover 121 and a second rear cover 122, which are fixedly connected and form another receiving space for accommodating the pump and drive unit 93.
[0065] The front end of the second front cover 121 is provided with a recessed mounting groove 1211, such as Figure 2 As shown, the mounting slot 1211 is used to receive the first rear cover 112.
[0066] In addition, such as Figure 8 As shown, the urine analyzer 100 also includes two locking members 13. The two locking members 13 are respectively connected to the first rear connecting ring 1121 and are symmetrically arranged on both sides of the first rear connecting ring 1121. The two locking members 13 can detachably connect the first rear cover 112 to the second front cover 121 of the second housing 12.
[0067] Specifically, such as Figures 6-9 As shown, the side wall of the mounting groove 1211 of the second front cover 121 is provided with two spaced locking grooves 1212. The two locking members 13 respectively include a locking tongue 131, a rotating member 132, and a handle 133. The rotating member 132 is rotatably connected to the first rear cover plate 1122 of the first rear cover 112 via a rotating shaft. The locking tongue 131 is connected to the rear end of the rotating member 132, and the handle 133 is also connected to the front end of the rotating member 132.
[0068] like Figure 7 As shown, the first front connecting ring 1111 has a handle clearance hole 1113. The handle 133 is plate-shaped, with its inner end connected to the front end of the rotating member 132, and its outer end extending to the outside of the first front connecting ring 1111 through the handle clearance hole 1113. Figure 2 , Figure 6 As shown, the first rear connecting ring 1121 is provided with a locking tongue relief hole 1123. The inner end of the locking tongue 131 is connected to the rotating part, and the outer end extends through the locking tongue relief hole 1123 into the locking groove 1212 and engages with the locking groove 1212.
[0069] like Figure 2 , Figure 6 As shown, when the first housing 11 needs to be disassembled, the handle 133 is pressed inward into the first housing 11, causing the rotating part 132 to rotate, which can move the locking tongue 131 out of the locking groove 1212. During installation, the handle 133 is rotated in the opposite direction to lock the locking tongue 131 into the locking groove 1212.
[0070] In addition, two limiting members 1124 are also provided on the first rear connecting ring 1121, such as... Figure 7As shown, the two limit members 1124 are located at both ends of the handle avoiding hole 1113, and the inner end of the handle 133 is also provided with two protrusions 134, which are located in the first rear connecting ring 1121 and are blocked by the two limit members 1124 to prevent the handle 133 from being separated from the first rear connecting ring 1121.
[0071] In other embodiments, a resilient member can also be arranged between the rotating member 132 and the inner wall of the first rear connecting ring 1121, which can pull the lock tongue 131 of the rotating member 132 to move towards the locking groove 1212 to prevent the lock tongue 131 from automatically separating from the locking groove 1212. Of course, in other embodiments, the lock tongue 131 and the locking groove 1212 are in interference fit, and the lock tongue 131 can also be locked.
[0072] It should be understood that in other embodiments, the first shell 11 and the second shell 12 can also be connected by clamping or magnetic attraction, or by bolts, and the present application does not limit the specific connection mode of the first shell 11 and the second shell 12.
[0073] The reagent kit 2 is installed in the first shell 11 and is provided with a plurality of reagent cavities 21 for containing reagents. Figures 10-11 As shown, the reagent kit 2 is a flat plate and is provided with a plurality of reagent cavities 21 and a plurality of flow channel holes 22, the plurality of reagent cavities 21 extend in the vertical direction and are arranged in the first direction, which is also the width direction of the urine test instrument 100. The reagent kit 2 is a plate and is stacked with the flow channel plate 3, the outer periphery of the reagent kit 2 is basically fitted with the inner wall of the first shell 11, and the plurality of reagent cavities 21 basically occupy the entire reagent kit 2, which can contain more reagents and will not occupy too much space.
[0074] As shown, Figure 6 , Figure 10 As shown, the first front connecting ring 1111 and the first rear connecting ring 1121 of the first shell 11 are annular, that is, the inner side wall of the first shell 11 is arc-shaped, and the bottom end of the reagent kit 2 is also arc-shaped, and the bottom ends of the plurality of reagent cavities 21 are arranged around a horizontal axis and are basically on the same circumference, and the bottom ends of the plurality of reagent cavities 21 are close to the bottom end of the reagent kit 2 to increase the utilization rate of the reagent cavities 21.
[0075] As shown, Figure 10 As shown, the bottom wall of the reagent cavity 21 includes an inclined surface 23 and a vertical surface 24, the vertical surface 24 extends in the vertical direction, and the inclined surface 23 is a slope that gradually decreases from back to front, and the bottom end of the inclined surface 23 is connected with the top surface of the vertical surface 24.
[0076] The top end and front side of the reagent cavity 21 are open, and reagent can be put into the top end. A seal can be arranged at the top end of the reagent cavity 21, or an oil seal can be used. The front end of the reagent box 2 is also provided with a sealing plate (not shown in the figure), which is stacked on the front side of the reagent box 2 and can seal the reagent cavity 21. Of course, if it is convenient to process, the sealing plate can not be arranged, and the front side of the sealing cavity can be provided with a sealing shape.
[0077] As shown in Figure 10 and Figure 11 , and the plurality of flow channel holes 22 are also arranged at intervals around the horizontal axis and recessed from the rear side of the reagent box 2 to the front end, and the plurality of flow channel holes 22 are recessed to the vertical surface 24 and communicate with the plurality of reagent cavities 21. The inclined surface 23 is arranged to facilitate the slow flow of reagent into the bottom end and from the flow channel hole 22 into the flow channel plate 3.
[0078] As shown in Figure 10 and Figure 11 , the rear side of the reagent box 2 is also provided with a plurality of sealing grooves 25, and the plurality of sealing grooves 25 are recessed from the rear side of the reagent box 2, and the plurality of flow channel holes 22 are recessed to the vertical surface 24 away from the inner wall of the second shell 12. The sealing groove 25 can also be tapered, that is, the sealing groove 25 gradually decreases from back to front, and the outer opening is larger.
[0079] As shown in Figure 7 , Figure 12 , the microfluidic chip comprises the flow channel plate 3 and the cover plate 7 stacked on the front side of the flow channel plate 3, wherein the cover plate 7 is located on the rear side of the reagent box 2, the cover plate 7 is a thin plate and is stacked on the rear side of the reagent box 2 and the front side of the flow channel plate 3. The front side of the cover plate 7 is provided with a plurality of tapered insertion columns 71, and the plurality of insertion columns 71 are respectively located in the plurality of sealing grooves 25, and the plurality of sealing rings are sleeved outside the plurality of insertion columns 71, so that the plurality of insertion columns 71 and the plurality of sealing grooves 25 are sealingly connected.
[0080] As shown in Figure 7 , Figure 12 , the rear side of the cover plate 7 is also provided with a plurality of through holes 72, and the plurality of through holes 72 extend to the front end of the plurality of insertion columns and respectively communicate with the plurality of flow channel holes 22, and the reagent in the reagent cavity 21 can flow into the flow channel plate 3 through the flow channel hole 22 and the through hole 72 of the insertion column.
[0081] The cover plate 7 and the reagent box 2 are connected by clamping or bonding, or connected by a thermoplastic method, and the specific connection method of the cover plate 7 and the reagent box 2 is not limited in the utility model.
[0082] In Figures 11-13In the shown embodiment, the bottom end of the reagent box 2 is provided with a clamping groove 26, and the bottom end of the cover plate 7 is provided with a protruding clasp 73 which can be clamped into the clamping groove 26 of the reagent box 2, so that the reagent box 2 and the cover plate 7 can be quickly assembled.
[0083] The flow channel plate 3 is stacked on the back side of the cover plate 7, and the flow channel plate 3, the cover plate 7 and the reagent box 2 are fixedly connected with the first front cover plate 1112 or the first back cover plate 1122 of the first shell 11 through the same bolt, Figure 4 and Figure 7 In the shown embodiment, the inner walls of the first front cover plate 1112 and the first back cover plate 1122 of the first shell 11 are respectively provided with two mounting columns 14, and the mounting columns 14 of the first front cover plate 1112 and the first back cover plate 1122 abut against each other and are both provided with threaded holes, and the threaded hole of the mounting column 14 of the first back cover plate 1122 extends to the back side of the first back cover plate 1122, so that the bolt can be screwed into the threaded hole of the mounting column 14 of the first front cover plate 1112 from the back side of the first back cover plate 1122, thereby fixing the first back cover plate 1122 and the first front cover plate 1112.
[0084] In addition, as shown, Figure 7 the reagent box 2 is provided with a counterbore hole 27, and the first back cover plate 1122 is further provided with another mounting column 14, the threaded hole of which is oppositely arranged with the counterbore hole 27, and the inner end of the mounting column 14 is further provided with a flange, part of which can abut against the back side of the flow channel plate 3. By screwing the bolt into the counterbore hole 27 from the back side of the first back cover plate 1122, the reagent box 2, the cover plate 7 and the flow channel plate 3 can be fixed together on the first back cover plate 1122, and the reagent box 2, the cover plate 7 and the flow channel plate 3 are tightly attached.
[0085] The front side of the flow channel plate 3 is provided with a central hole 31, a plurality of circumferential holes 32, a common flow channel 33, a sample flow channel, a clean water flow channel, an air flow channel 36, a plurality of reagent flow channels 37 and a detection flow channel 38, as shown in Figures 14-16 The central hole 31 is located on the horizontal axis mentioned above, and the central hole 31 is a through hole 72 penetrating through the front and back of the flow channel plate 3. The plurality of circumferential holes 32 are located on the circumference with the central hole 31 as the center and are arranged at intervals, that is, the plurality of circumferential holes 32 are on the same circumference.
[0086] The inner ends of the sample flow channel, the inner ends of the clean water flow channel, the inner ends of the air flow channel 36, the inner ends of the detection flow channel 38 and the inner ends of the plurality of reagent flow channels 37 respectively extend to the plurality of circumferential holes 32 and communicate with the plurality of circumferential holes 32, and the outer ends of the sample flow channel, the outer ends of the clean water flow channel, the outer ends of the air flow channel 36, the outer ends of the detection flow channel 38 and the outer ends of the plurality of reagent flow channels 37 respectively disperse to other positions of the flow channel plate 3 away from the central hole 31, wherein the outer end of the detection flow channel 38 communicates with a detection cavity of a detection mechanism, facilitating the sample and the reagent to flow from the detection flow channel 38 into the detection cavity, and the outer ends of the plurality of reagent flow channels 37 respectively extend to another circle and align and communicate with the plurality of through holes 72 of the plurality of cover plates 7.
[0087] In some embodiments, one clean water flow channel and one sample flow channel are respectively arranged, the outer end of the clean water flow channel communicates with the clean water collection cavity 412 of the collection cavity through a pipeline, facilitating water to enter the clean water flow channel from the clean water collection cavity 412, and the sample flow channel communicates with the sample collection cavity 411 through a pipeline, facilitating the sample to enter the sample flow channel from the sample collection cavity 411.
[0088] In Figure 14 and 16 In the embodiments shown in the drawings, two clean water flow channels and two sample flow channels are respectively arranged, and the inner ends of the two clean water flow channels and the two sample flow channels respectively communicate with different circumferential holes 32. The use methods of the two clean water flow channels and the two sample flow channels will be described in detail below.
[0089] In order to facilitate the sample flow channel, the detection flow channel 38, the reagent flow channel 37 and the air flow channel 36 to communicate with the sample collection cavity 411, the detection cavity and the reagent cavity 21, the rear side of the flow channel plate 3 is further provided with a first adapter 301, which can be installed in the first shell 11 or the second shell 12.
[0090] Specifically, as shown in Figure 18 and Figure 19 If the first adapter 301 is installed in the first shell 11, the first adapter 301 is connected with the rear side of the flow channel plate 3 through clamping, bolt fixing, welding or the like, and the specific connection mode of the first adapter 301 and the rear side of the flow channel plate 3 is not limited.
[0091] The first adapter 301 is used to introduce the sample and the clean water into the microfluidic chip, and also used to discharge the waste liquid after detection in the detection plate into the collector and then into the closestool. Moreover, after the reagent is used up, the first adapter 301 and the pipeline are disassembled together, and all the components in the first shell are directly replaced, which reduces pollution and improves the service life of the urine testing instrument.
[0092] As shown in Figure 18 , Figure 26 , Figure 27As shown, the first adapter 301 is provided with seven adapter tubes, which are used to communicate with the sample collection cavity 411, the clean water collection cavity 412, the drain passage 416 of the detector or the external air through a plurality of pipes. The adapter tubes are preferably arranged at the top end of the first adapter 301, which facilitates the flow of samples or water from the sample collection cavity 411 or the clean water collection cavity 412 into the flow channel plate 3, and also facilitates the flow of liquid in the detection cavity from the connecting pipe and the pipe into the drain passage 416 of the collector.
[0093] As shown in Figure 18 , Figure 26 , Figure 27 of the seven adapter tubes, two of them communicate with the sample collection cavity 411 of the collector, which are defined as sample adapter tubes 3011. Another two of them communicate with the clean water collection cavity 412 of the collector, which are defined as clean water adapter tubes 3012. Another one of them communicates with the air flow channel 36 of the flow channel plate 3, which is defined as an air adapter tube 3013. Another one of them communicates with the drain passage 416 of the collector, which is defined as a drain adapter tube 3014. The last one of them communicates with the driving pipe, which is defined as a driving adapter tube 3015.
[0094] As shown in Figure 18 , the front side of the first adapter 301 is provided with seven first insertion slots 3016, and the first adapter 301 is provided with seven channels, which extend towards and communicate with the seven adapter tubes. The bottom ends of the seven channels communicate with the plurality of first insertion slots 3016.
[0095] As shown in Figure 14 , Figure 17 , the rear side of the flow channel plate 3 is also provided with nine first adapter columns 3017, each of which is provided with a first adapter hole, which extends into the flow channel plate 3 and communicates with the clean water flow channel, the detection flow channel 38, the sample flow channel or the air flow channel 36 of the flow channel plate 3. Seven of the nine first adapter columns 3017 are inserted into the seven first insertion slots 3016 of the first adapter, and the other two need to be inserted into the flow inlet and flow outlet of the detection plate. Of the seven first adapter columns 3017, the first adapter holes of two of them communicate with two sample flow channels of the flow channel plate 3, and the first adapter holes of the two first adapter columns 3017 also communicate with two sample adapter tubes 3011. The first adapter holes of the other two first adapter columns 3017 communicate with two clean water flow channels, and also communicate with two clean water adapter tubes 3012.
[0096] As shown in Figure 14 , Figure 17 , Figure 18As shown, the first adapter hole of one of the first adapter posts 3017 is connected to the air flow channel 36 and the air adapter pipe 3013. The first adapter hole of another first adapter post 3017 is connected to the drive pipe and the drive adapter pipe 3015. There are also three first adapter holes of the first adapter posts 3017, one of which is used to connect to the sewage adapter pipe 3014, and the other two are used to connect to the detection chamber respectively. These will be described in detail below.
[0097] In summary, the seven first adapter posts 3017 are respectively inserted into the seven first slots 3016 of the first adapter, thereby connecting the outer end of the sample flow channel of the flow channel plate 3 to the sample adapter pipe 3011, the outer end of the clean water flow channel to the clean water adapter pipe 3012, the outer end of the air flow channel 36 to the air adapter pipe 3013, and the outer end of the detection flow channel 38 to the sewage adapter pipe 3014.
[0098] In another embodiment, the first adapter 301 is installed inside the second housing 12 or in the mounting slot. Since the second housing 12 and the first housing 11 are detachably connected, regardless of whether the first adapter 301 is connected inside or outside the second housing 12, the plurality of first slots 3016 of the first adapter 301 need to be exposed in the mounting slot 1211 of the second housing 12.
[0099] like Figure 17 As shown, the rear side of the flow channel plate 3 is also provided with multiple first adapter posts 3017, and the first rear cover plate 1122 of the first housing 11 also needs to be provided with avoidance holes to avoid multiple first adapter posts 3017, so that the first adapter posts 3017 can be inserted into the first slot 3016 of the first adapter 301 as the first housing 11 and the second housing 12 are assembled.
[0100] like Figure 6 , Figure 17 , Figure 18 As shown, when the first housing 11 and the second housing 12 are assembled, when the locking tongue 131 of the locking member 13 is inserted into the locking groove 1212, it can simultaneously squeeze multiple first adapter pins 3017 into multiple first slots 3016.
[0101] Of course, in order to increase the sealing performance of the first adapter 301 and the flow channel plate 3, a sealing ring fitted around the first adapter post 3017 is also required in the first slot 3016.
[0102] like Figure 18 , Figure 19 As shown, the detection plate 5 can be installed inside the first housing 11 and fixedly connected or snapped to the first adapter 301, or fixedly connected to the rear side of the flow channel plate 3. Of course, in other embodiments, the detection plate 5 can also be disposed inside the second housing 12 and configured to be snapped and detached from the first adapter 301.
[0103] Figure 14 、 19 As shown in FIG. 1 1, if the detection plate 5 is arranged in the first housing 1 1, the detection plate 5 can be directly fixed to the rear side of the flow channel plate 3, one end of the detection cavity is communicated with the detection flow channel 38, and the other end is communicated with the pollution adapter pipe 3014 of the first adapter 301, which is communicated with the pollution passage 416 of the collector through a pipeline. The liquid in the detection flow channel 38 flows into the detection cavity for detection, and after the detection is completed, the liquid in the detection cavity can flow into the pollution passage 416 from the pollution adapter pipe 3014, and then be discharged into the closestool from the pollution passage 416.
[0104] Specifically, as shown in FIG. 1 1, Figure 5 、 Figure 19 、 Figure 21 The detection plate 5 is a plate-shaped plate extending along the front and back of the urinalysis instrument 100, and the detection cavity is generally U-shaped and has a flow inlet 51 and a flow outlet 52, which are respectively located at the front end of the detection plate 5. As shown in FIG. 1 1, Figure 17 Two of the three first adapter columns 3017 at the rear side of the flow channel plate 3 are respectively inserted into the flow inlet 51 and the flow outlet 52, and the first adapter column 3017 inserted into the flow inlet 51 communicates the detection flow channel 38 of the flow channel plate 3 with the flow inlet 51, so that the sample and the liquid in the detection flow channel 38 can flow into the detection cavity in sequence for detection. That is, one end of the detection cavity is communicated with the detection flow channel, and the other end is communicated with the pollution pipeline.
[0105] As shown in FIG. 1 1, Figure 14 、 Figure 17 、 Figure 18 The flow channel plate 3 is further provided with a pollution flow channel 302, both ends of which are respectively communicated with the other two first adapter columns 3017 at the rear side of the flow channel plate 3, one of the two first adapter columns 3017 is inserted into the flow outlet 52 of the detection cavity, and the first adapter hole of the first adapter column 3017 is communicated with the flow outlet 52. The other first adapter column 3017 is inserted into the first slot 3016 at the front end of the first adapter 301, and is communicated with the pollution adapter pipe 3014 at the top end of the first adapter 301.
[0106] That is, the mixed liquid of the sample and the reagent in the detection flow channel 38 flows into the detection cavity from the first adapter hole of one of the first adapter columns 3017 and the flow inlet 51 of the detection cavity, and after the detection is completed, the mixed liquid flows into the pollution flow channel 302 of the flow channel plate 3 from the flow outlet 52, and then flows into the pollution adapter pipe 3014 from the pollution flow channel 302, flows into the pollution passage 416 of the collection cavity from the pollution adapter pipe 3014 and the pipeline, and then flows into the closestool from the pollution passage 416.
[0107] The pollution flow channel 302 is equivalent to a transfer flow channel, one end of which is communicated with the flow outlet 52 of the detection chamber, and the other end is communicated with the pollution transfer pipe 3014, and the mixed liquid in the detection chamber flows from the pollution flow channel 302 and then from the pollution transfer pipe 3014 into the pollution channel 416. With this design, the volume of the first transfer piece 301 can be reduced, and the internal space of the flow channel plate 3 and the first transfer piece 301 can be fully utilized.
[0108] When the reagent in the first shell 11 is consumed, the detection plate 5 can be removed together with the first shell 11. When a new detection device is replaced, a new detection plate 5 is also installed in the internal.
[0109] The detector of the utility model includes a light source device and a photosensitive sensor, and the light source device and the photosensitive sensor are arranged at corresponding positions of the detection plate 5. The detection plate 5 is made of transparent material, the light source device is LED light, and is used for irradiating the mixed liquid in the detection chamber, and the photosensitive sensor is used for sensing the light after the light source device irradiates the mixed liquid, so as to detect the sample component. However, the detector is relatively complex to install, so in order to facilitate the customer to assemble, the detector needs to be installed in the second shell 12, that is, the detector and the detection plate 5 are assembled separately. The detector needs to be close to the detection plate 5 to detect the mixed liquid in the detection chamber, so the rear end of the detection plate 5 needs to extend into the second shell 12.
[0110] Specifically, as shown in Figure 20 The first rear cover plate 1122 of the first shell 11 and the inner wall of the mounting groove 1211 of the second shell 12 need to be provided with avoiding holes respectively, the avoiding holes are detection plate avoiding holes 15, the front end of the detection plate 5 is connected with the flow channel plate 3 and the first transfer piece 301, the rear end extends into the second shell 12 from the two detection plate avoiding holes 15 of the first shell 11 and the second shell 12, and the detector is installed at the top or the bottom of the detection plate avoiding hole 15 of the second shell 12, so as to detect the liquid in the detection chamber.
[0111] In another embodiment, the detection plate 5 can also be directly installed in the second shell 12, the front end of the detection plate 5 extends to the inner wall of the mounting groove 1211, and the first transfer holes of two of the three first transfer columns 3017 at the rear end of the flow channel plate 3 are communicated with the two ends of the pollution flow channel 302 respectively, the first transfer hole of one of the two first transfer columns 3017 is communicated with the pollution transfer pipe 3014, and the first transfer hole of the other is communicated with the flow outlet 52 of the detection chamber.
[0112] The first transfer hole of the other first transfer column 3017 of the three first transfer columns 3017 is communicated with the flow inlet 51 of the detection chamber.
[0113] Two first adapter columns 3017, which are in communication with the flow inlet 51 and the flow outlet 52 of the detection cavity, need to extend to the rear side of the first rear cover plate 1122 of the first shell 11. When the first shell 11 and the second shell 12 are assembled, the rear ends of the two first adapter columns 301 can be inserted into the two flow inlets 51 and the flow outlet 52 at the front end of the detection plate 5, so that the first shell 11 and the second shell 12 can be quickly disassembled and assembled.
[0114] It should be understood that the multiple adapter tubes and the multiple first adapter columns 3017, or the first adapter columns and the flow outlet 52 and the flow inlet 51, need to be connected in a sealed manner. The sealing method can be a sealing ring or other methods.
[0115] The common flow channel 33 is a curved flow channel, and the inner end extends to the center hole 31 and is in communication with the center hole 31. The outer end is curved and extends to the outside of the flow channel plate 3 after winding around the center hole 31 once in the circle formed by the multiple circumferential holes 32. The common flow channel 33 and the multiple circumferential holes 32 are arranged in a staggered manner and are not directly connected to each other.
[0116] In an embodiment, the outer end of the common flow channel 33 is used to communicate with a driving pipe. The driving pipe is located in the second shell and is connected with a pump. The pump can exhaust the air in the driving pipe and the common flow channel 33. Of course, in some embodiments, two pumps can be connected in series through the pipe, and one of the pumps is connected with the driving pipe.
[0117] In Figure 14 In the embodiment shown, the middle part of the common flow channel 33 is provided with at least one curved channel. On the one hand, the volume of the common flow channel 33 is increased. On the other hand, the reagent or sample in the common flow channel 33 is prevented from flowing back into the driving pipe.
[0118] The common flow channel 33 needs to be in communication with the driving pipe. The pump is connected with the driving pipe. After the pump is started, the air in the common flow channel 33 can be exhausted to form a negative pressure.
[0119] The pump and the driving pipe are respectively located in the second shell 12. Therefore, in order to quickly disassemble and assemble the driving pipe and the common flow channel 33, a second adapter 306 needs to be installed. The second adapter 306 will be introduced below.
[0120] As a preferred solution, in order to more accurately quantitatively extract the reagent and the sample, two pumps can be used to communicate with the common flow channel through two driving pipes. One is a peristaltic pump 91, and the other is a plunger pump 92. The two pumps are respectively installed in the second shell 12 and are respectively connected with the two driving pipes. The two driving pipes are respectively defined as a first driving pipe and a second driving pipe.
[0121] The second drive pipe is connected to the plunger pump, and the first drive pipe is connected to the peristaltic pump 91. The first drive pipe includes two sections, the two ends of which are respectively connected to the two ends of the hose of the peristaltic pump, and the other two sections are respectively connected to the two peristaltic pump adapters 3041 described below.
[0122] The front side of the flow channel plate 3 also has a drive flow channel 303, which extends vertically and its top end is connected to a first adapter hole of one of the first adapter posts 3017, which is connected to the drive adapter pipe 3015.
[0123] The rear side of the flow channel plate 3 is also provided with three second adapter posts, each of which is provided with a second adapter hole. Among the three second adapter posts, two are peristaltic pump adapter posts 3041 and the other is plunger pump adapter post 3042.
[0124] like Figure 14 , Figure 17 As shown, the second adapter hole of one of the two peristaltic pump adapter pins 3041 is connected to the bottom end of the drive flow channel 303, and the second adapter hole of the other peristaltic pump adapter pin 3041 is connected to the common flow channel 33.
[0125] The plunger pump adapter 3042 is located between the two peristaltic pump adapters 3041, and its second adapter hole is also connected to the common flow channel 33.
[0126] Figure 17 , Figure 18 As shown, the second adapter 306 is connected to the inner wall of the mounting groove 1211 of the second housing 12, and is provided with three second slots 3061. Among the three second slots 3061, two of the second slots 3061 respectively accommodate two peristaltic pump adapter columns 3041. That is, the common flow channel 33 is connected to one end of a section of the first drive pipe through one peristaltic pump adapter column 3041, and one end of the other section of the first drive pipe is connected to the bottom end of the drive flow channel 303 through another peristaltic pump adapter column 3041. The top end of the drive flow channel 303 is connected to the drive adapter pipe 3015 through the first connecting column. The drive adapter pipe 3015 can also be connected to the collector. In other words, one end of each section of the first drive pipe is connected to both ends of the peristaltic pump hose, and the other end is connected to the common flow channel and the drive adapter pipe 3015 respectively. After the peristaltic pump is started, it can draw the fluid in the common flow channel from the first drive pipe and the drive adapter pipe to the collector, and then discharge it from the collector into the toilet.
[0127] Of the three second slots 3061, another second slot 3061 is connected to one end of the second drive pipe, and this second slot 3061 accommodates the plunger pump adapter 3042.
[0128] The peristaltic pump 91 is used to drive the air in the common flow channel 33 to discharge, or to drive the sample in the sample collection cavity, water into the sample flow channel and the water flow channel, that is, a larger air flow is required, so the driving flow channel 303 is arranged on the flow channel plate 3, and the driving adapter pipe 3015 is arranged on the first adapter 301, which can provide a larger air flow if arranged in a bending manner. The plunger pump 92 only needs to quantitatively extract the sample and reagent in the sample flow channel and the reagent flow channel 37 into the common flow channel, and a smaller flow is required, so one end of the second driving pipe is communicated with the common flow channel 33, and the other end is arranged near the plunger pump 92.
[0129] As shown in Figure 5 , the detection flow channel 38 is communicated with the detection cavity, and the mixing cavity 39 is further arranged on the path of the detection flow channel 38, the mixing cavity 39 is communicated with the detection flow channel 38, and the width of the mixing cavity 39 is greater than the diameter size of the detection flow channel 38. When the sample and the reagent flow in the detection flow channel 38, they pass through the mixing cavity 39, and because the width of the mixing cavity 39 is larger, the sample and the reagent will accelerate when flowing from the detection flow channel 38 into the mixing cavity 39, and then mix in the mixing cavity 39.
[0130] As a preferred solution, the mixing cavity 39 comprises a mixing elbow 392 and at least one mixing chamber 391 communicated with each other, the mixing elbow 392 is an S-shaped curved flow channel, and the mixing chamber 391 is communicated with the mixing elbow 392, and the width size of the mixing cavity 39 is greater than the diameter size of the mixing elbow 392 and the detection flow channel 38.
[0131] In Figures 14-16 the embodiment shown, the mixing cavity 39 comprises three mixing elbows 392 and three mixing chambers 391, the three mixing chambers 391 and the three mixing elbows 392 are alternately arranged and communicated with each other, and the inlet of the mixing cavity 39 is at the bottom end and the outlet is at the top end. That is, the three mixing elbows 392 and the mixing cavity 39 present a curved upward extension.
[0132] The mixing elbow 392 comprises at least two horizontal flow channels and at least one turning flow channel 394, and any one of the turning flow channels 394 is located at the two ends of the two horizontal flow channels;
[0133] The mixing elbow 392 is an S-shaped elbow and comprises at least two horizontal flow channels and at least one turning flow channel 394, the horizontal flow channel is a flow channel extending in the horizontal direction, and the turning flow channel 394 is located between any two horizontal flow channels, that is, at the corner of the mixing elbow 392.
[0134] As shown in Figure 16 , the turning flow channel 394 comprises a curved inner arc 395 and an outer arc 396, the inner arc 395 and the outer arc 396 are both arc-shaped, and the inner diameter of the inner arc 395 is smaller than the inner diameter of the outer arc 396.
[0135] The mixing cavity 39 adopts the S-shaped mixing elbow 392 and the mixing cavity 39 cooperates, and the outer diameter of the turning corner of the mixing elbow 392 is enlarged, the flow velocity at the outer arc 396 is greater than that at the inner arc 395, the local Dean flow effect is formed, and the mixing effect of the mixed liquid of the sample and the reagent in the flow channel is improved.
[0136] As shown in Figure 15 , the cross section of the mixing chamber 391 along the vertical direction is approximately circular, and the two side walls of the mixing chamber 391 are also arc surfaces, and the two arc surfaces are a first arc surface 397 and a second arc surface 398 opposite to the first arc surface 397, and the first arc surface 397 and the second arc surface 398 are both arc surfaces protruding outward.
[0137] As a preferred solution, as shown in Figure 15 , the first arc surface 397 and the second arc surface 398 are circular arc surfaces with the same diameter and the same arc length, and the tangent lines at the two ends of the first arc surface 397 and the second arc surface 398 are parallel to each other. In the embodiment shown in the figure, the arc length of the first arc surface 397 is equal to 1 / 4 of the circumference, and the tangent lines at the two ends are perpendicular to each other, and one of the tangent lines extends in the vertical direction, and the other extends in the horizontal direction.
[0138] Since the entire mixing cavity 39 extends along the vertical direction, as shown in Figure 16 , each mixing chamber 391 is located between two mixing elbows 392, and each mixing cavity 39 needs to be connected with the horizontal flow channels of the two mixing elbows 392, and the two horizontal flow channels are mirror-symmetrically arranged, one of which is located at the top end of the mixing chamber 391, and the other is located at the bottom end of the mixing chamber 391.
[0139] Of the two horizontal flow channels connected with the mixing chamber 391, one of the horizontal flow channels is defined as the liquid inlet horizontal flow channel 3931, and the other horizontal flow channel is defined as the liquid outlet horizontal flow channel 3932, the liquid inlet horizontal flow channel 3931 is connected with the top end of the mixing chamber 391, and the liquid outlet horizontal flow channel 3932 is connected with the bottom end of the mixing chamber 391. The sample or reagent flows into the mixing chamber 391 from the liquid inlet horizontal flow channel 3931, and then flows out from the liquid outlet horizontal flow channel 3932. That is to say, the liquid inlet horizontal flow channel 3931 is located upstream of the liquid outlet horizontal flow channel 3932, the sample and the reagent flow into the detection flow channel 38 from the common flow channel 33, and after the mixing cavity 39, the sample and the reagent flow into the mixing chamber 391 from the liquid inlet horizontal flow channel 3931 of one mixing elbow 392, and then flow into the horizontal flow channel of the other mixing elbow 392.
[0140] As shown in Figure 15As shown, the mixing chamber 391 has a sample inlet 3911 and a sample outlet 3912, wherein the sample inlet 3911 is communicated with the liquid inlet horizontal flow channel of one of the mixing bends, and the sample outlet 3912 is communicated with the liquid outlet horizontal flow channel 3932 of the other mixing bend. The sample and reagent can flow from the liquid inlet horizontal flow channel of one of the mixing bends, the sample inlet 3911, into the mixing chamber, and then from the sample outlet 3912 and the liquid outlet horizontal flow channel into the other mixing bend, and continuously flow in several mixing chambers and several mixing bends.
[0141] As shown, the line between the liquid inlet horizontal flow channel 3931 and the liquid outlet horizontal flow channel 3932 is a dividing line, and the dashed line shown is a dividing line. The dividing line can divide the mixing chamber 391 into two parts, wherein the area formed by the dividing line and the first arc surface 397 located below is a slow area 3934, and the area between the dividing line and the second arc surface 398 is a fast area 3933. The flow has a certain speed difference between the fast area 3933 and the slow area 3934 of the mixing chamber 391 into which the liquid flows from the liquid inlet horizontal flow channel 3931. The mixed liquid of the sample and the reagent forms a vortex around the center point in the circular mixing chamber 391, increases the contact area between the liquids, and improves the mixing effect. Figure 15
[0142] Due to the narrowing of the liquid outlet horizontal flow channel 3932, when the mixed liquid of the sample and the reagent flows out of the liquid outlet horizontal flow channel 3932, the speed increases suddenly, and the mixed liquid of the sample and the reagent is relatively squeezed, and the mixing intensity of the mixed liquid of the sample and the reagent is increased again. Through the series connection of the mixing bends 392 with multiple variable-diameter treatments and the circular mixing chamber 391, the mixing intensity is gradually increased until the detection cavity, and the sample and the reagent are basically in a completely mixed state.
[0143] The mixing cavity 39 of the utility model is commonly used in the technical field of microfluidic chips such as biology and chemistry. When the sample or the reagent or the sample and the reagent need to be mixed, this structure can greatly improve the mixing efficiency and avoid some residual and bubble problems.
[0144] In the mixing cavity 39, the liquid inlet horizontal flow channel 3931 communicated with each mixing chamber 391 is relatively higher than the liquid outlet horizontal flow channel 3932. In a special application scenario, such as vertical use, when the liquid flows from bottom to top, the influence of gravity does not need to be considered, so that residual problems will not occur in the mixing chamber 391.
[0145] When the sample or the reagent flows in a relatively rough flow channel, bubbles are easily generated, which affects the mixing effect and even brings into the detection cavity, causing analysis errors. The multiple mixing cavities 39 and the mixing bends 392 of the chip are connected in series, and the flow channel corners of each mixing bend 392 are all smoothly rounded and transitioned, which can avoid and eliminate bubbles in the mixing chamber 391 to a certain extent.
[0146] The inlet of the mixing cavity 39 is located below the outlet, the mixing cavity 39 is located above the common flow channel 33, the inlet of the mixing cavity 39 and the common flow channel 33 are communicated, and the outlet and the detection cavity are communicated. After the sample and the reagent of the common flow channel 33 flow into the mixing cavity 39 from the bottom end inlet of the mixing cavity 39, the sample and the reagent flow into the detection cavity from the outlet.
[0147] As shown in Figure 14 , Figure 22 , the rotor 6 is rotatably installed in the first housing 11 and located at the rear side of the flow channel plate 3. The rotor 6 is internally provided with a transfer channel. The inner end 61 and the outer end of the transfer channel are open towards the front side of the rotor 6. The transfer channel is substantially in a U shape. The inner end 61 of the transfer channel is aligned with the central hole 31. The inner end is recessed from the front side of the rotor 6 to the inside of the rotor 6. The outer end 62 of the transfer channel is also open towards the front side of the rotor 6. The distance from the outer end 62 to the inner end 61 is the same as the distance from the central hole 31 to the plurality of circumferential holes 32.
[0148] As shown in Figure 14 , Figure 22 , the inner end 61 of the transfer channel is aligned with and communicated with the central hole 31. The outer end 62 rotates with the rotor 6 and can be aligned and communicated with any one of the circumferential holes 32 with the rotation of the rotor 6.
[0149] When it is necessary to extract the sample, the rotor 6 is rotated so that the outer end 62 of the transfer channel is aligned with the circumferential hole 32 which is communicated with the inner end of the sample flow channel. At this time, the two ends of the transfer channel are communicated with the sample flow channel and the common flow channel 33 respectively. The peristaltic pump 91 can extract the air in the common flow channel 33, the transfer channel, the sample flow channel and the external sample adapter pipe or the pipe communicated with the adapter pipe, form a negative pressure, and extract the sample in the sample collection cavity 411 to the common flow channel 33.
[0150] When it is necessary to extract the reagent, the same operation is performed. The rotor 6 is rotated so that the outer end 62 of the transfer channel is aligned with the circumferential hole 32 which is communicated with the reagent flow channel 37. The common flow channel 33 is communicated with the reagent channel. The peristaltic pump 91 extracts the air in the common flow channel 33 and the reagent channel, forms a negative pressure, and extracts the reagent in the reagent cavity 21 to the common flow channel 33.
[0151] When it is necessary to extract the clean water in the clean water collection cavity 412, the same operation is performed, which will not be described in detail.
[0152] After the sample and the reagent are extracted into the common flow channel 33, the rotor 6 continues to rotate so that the outer end 62 of the transfer channel is aligned with the circumferential hole 32 which is communicated with the inner end of the detection flow channel 38. The peristaltic pump 91 drives the sample and the reagent in the common flow channel 33 to flow from the common flow channel 33 into the detection flow channel 38, and then flow from the detection flow channel 38 into the detection cavity.
[0153] In the embodiment where the mixing chamber 39 is provided, the peristaltic pump 91 can push the sample and reagent from the detection inlet into the mixing chamber 39, pushing the sample and reagent from the bottom inlet to the top outlet of the mixing chamber 39. To improve the mixing effect, the peristaltic pump 91 can also be used to repeatedly backflow the sample and reagent through the mixing chamber 391 and the mixing bends 392. After passing through the mixing chamber 391 and multiple mixing bends 392, the sample and reagent are repeatedly mixed to form a mixed liquid until the mixing effect is achieved. Finally, the mixed liquid flows into the detection chamber from the inlet 51 of the detection chamber.
[0154] As described above, the flow channel plate 3 is also provided with a sewage discharge channel 302. Both ends of the sewage discharge channel 302 are respectively connected to the first adapter holes of two other first adapter posts 3017 on the rear side of the flow channel plate 3. One of the two first adapter posts 3017 is inserted into the outlet 52 of the detection chamber, and the first adapter hole of this first adapter post 3017 is connected to the outlet hole. The other first adapter post 3017 is inserted into the first slot 3016 at the front end of the first adapter 301 and is connected to the sewage discharge adapter pipe 3014 located at the top of the first adapter 301.
[0155] After the test is completed, the pump drives air into the test channel 38 and the test chamber, and the mixed liquid flows from the outlet 52 of the test chamber into the sewage channel 302, and then from the sewage channel 302 into the sewage transfer pipe 3014. From the sewage transfer pipe 3014 and the pipe, it flows into the sewage channel 416 of the collector, and then into the toilet.
[0156] The rotor 6 is rotatably connected to the rear side of the flow channel plate 3. In a specific embodiment, the rear side of the flow channel plate 3 is also provided with a connector 85. The connector 85 is a ring extending around the outside of multiple circumferential holes 32 and is located on the radial outer side of the rotor 6.
[0157] The rotor 6 is also covered by a protective cover 81, such as Figure 22 and 23 As shown, the protective cover 81 covers the connector 85 and is also snapped into the connector 85, and the rotor 6 rotates on the protective cover 81.
[0158] In addition, such as Figure 22 , Figure 23 As shown, in order to drive the rotor 6 against the rear side of the flow channel plate 3 and prevent liquid from overflowing from the circumferential hole 32, a compression spring 82 is also provided inside the protective cover 81. A convex ring 83 is also provided on the rear side of the rotor 6. The compression spring 82 is sleeved around the convex ring 83, and its front and rear ends abut against the rear side of the rotor 6 and the rear wall of the protective cover 81, thereby ensuring a tight fit between the rotor 6 and the flow channel plate 3. Of course, the compression spring 82 can also be replaced with other biasing components, such as magnets attracting each other on the rotor 6 and the flow channel plate 3.
[0159] The drive unit 93 is located within the second housing 12 and is detachably connected to the rotor 6, such as Figure 24 As shown, the drive component 93 can be a motor, or other drive methods can be selected. The motor shaft extends into the mounting slot 1211 of the second housing 12. After the second housing 12 and the first housing 11 are assembled, the motor shaft and rotor 6 can be automatically assembled.
[0160] Specifically, the first rear cover plate 1122 of the first housing 11 has a clearance hole for the protective cover 81, and the inner wall of the mounting groove 1211 of the second housing 12 also has a clearance hole for the motor shaft. The rear side of the protective cover 81 is located within the clearance hole of the first rear cover plate 1122 and also has a through hole, while the shaft of the drive component 93 extends from the clearance hole in the inner wall of the mounting groove 1211 into the protective cover 81. Furthermore, the rear side of the convex ring 83 has a recessed spline groove 84, such as... Figure 23 and 24 As shown, the front end of the motor shaft is provided with a spline 931 located in the spline groove 84. When the first housing 11 and the second housing 12 are assembled, the spline 931 of the shaft is inserted into the spline groove 84 to complete the assembly.
[0161] The collector is located outside the first housing 11 and the second housing 12, and is connected to the adapter pipe of the first adapter 301 through multiple pipes.
[0162] exist Figures 25-27 In the illustrated embodiment, the collector includes a collection plate 41, an outer cover plate 43, an inner cover plate 42, and a clean water collection component. The collection plate 41 is disc-shaped and has an outer side and an inner side. The outer side is the side away from the toilet, while the inner side is the side closer to the toilet. A sample collection chamber 411 is provided on the outer side of the collection plate 41, and a clean water collection chamber 412 is provided on the rear side.
[0163] The sample collection chamber 411 is located at the top of the collection plate 41 and its width gradually increases from the bottom to the top, opening towards the top of the collection plate 41 for collecting samples. The water collection chamber 412 is located at the bottom of the collection plate 41 and is offset from the sample collection chamber 411.
[0164] The top of the collection plate 41 is also provided with a water inlet channel 413, a water outlet channel 414, and a sample outlet channel 415. The water inlet channel 413 and the water outlet channel 414 are respectively connected to the clean water collection chamber 412. The water inlet channel 413 and the water outlet channel 414 are both located on the rear side of the collection plate 41 and are recessed from the top of the collection plate 41 into the clean water collection chamber 412.
[0165] The sample collection cavity 411 is located on the front side of the collection plate 41, and is formed by a groove recessed from the front side of the collection plate 41. The sample collection cavity 411 is formed by combining the collection plate 41 and the outer cover plate 43. The top end of the front cover plate is provided with a filter part 44. The filter part 44 is a grid arranged at intervals on the top end of the front cover plate. A filter screen or the like can also be added to filter foreign matter.
[0166] The inner walls on both sides of the sample collection cavity 411 are arc surfaces protruding towards each other, so that the width of the sample collection cavity 411 gradually increases from the bottom end to the top end. In addition, the arc-shaped inner side walls can increase the opening of the sample collection cavity 411, and also facilitate the flow of samples from the top end to the bottom end.
[0167] The inner walls of the sample collection cavity 411 are also provided with two recessed drainage grooves 4111. The two drainage grooves 4111 are recessed downward from the top end of the collection plate 41 and arranged at intervals. A partition column 402 is formed between the two drainage grooves 4111, and the partition column 402 is located substantially in the middle of the sample collection cavity 411. The shapes of the two drainage grooves 4111 are substantially the same. The bottom walls of the two drainage grooves 4111 are also arc surfaces recessed downward.
[0168] The drainage grooves 4111 facilitate the reception of more samples, and also facilitate the flow of samples along the inner walls of the drainage grooves 4111. The large flow channel arc surfaces provide a slow flow of samples into the bottom end of the sample collection cavity 411, reducing the generation of air bubbles.
[0169] It should be understood that if the sample collection cavity 411 has sufficient space, multiple drainage grooves 4111 can also be provided. The multiple drainage grooves 4111 can be arranged at intervals along the width direction of the collector. The inner walls and bottom walls of the multiple drainage grooves 4111 are preferably smooth arc surfaces.
[0170] The bottom end of the sample collection cavity 411 is also provided with a drain port 417. The drain port 417 is open towards the bottom end of the collection cavity, and the diameter of the drain port 417 is very small. During the sample collection process, the drain port 417 is always open. Due to its small diameter, it does not affect the sample collection.
[0171] A liquid level sensor is also provided in the sample collection cavity 411. The liquid level sensor is located below the two drainage grooves 4111 and adjacent to the drainage grooves 4111, and is used to sense the liquid level of the collected samples.
[0172] In addition, the sample outlet channel 415 is recessed from the back side of the collection plate 41, and the bottom end of the sample outlet channel 415 extends into the sample collection cavity 411 and is located above the drain port 417. The top end of the sample outlet channel 415 is located at the upper end of the collection plate 41, and the top end of the sample outlet channel 415 is connected to the sample adapter pipe 3011 through a pipe. The samples in the sample collection cavity 411 can flow into the sample flow channel from the sample outlet channel 415 and the sample adapter pipe 3011.
[0173] The clean water collecting cavity 412 is formed by recessing the rear side of the collecting plate 41, and the inner cover plate 42 covers the clean water collecting cavity 412 to form a closed cavity after being connected to the rear side of the collecting plate 41.
[0174] The clean water collecting cavity 412 includes a first cavity 4121 and a second cavity 4122, which are symmetrically arranged on both sides of the sample collecting cavity 411 and are connected at the bottom, and exhaust holes 418 are arranged at the top ends of the first cavity 4121 and the second cavity 4122, respectively.
[0175] The water inlet channel 413 and the water outlet channel 414 are respectively formed by recessing the rear side of the collecting plate 41, and the bottom end of the sample outlet channel 415 is connected to the bottom end of the sample collecting cavity 411.
[0176] The top end of the water inlet channel 413 is also connected to an external clean water collecting member, which can be a pipeline connected to a clean water pool or a water switch, or a pipeline directly arranged on the inner wall of the closestool above the collector for collecting clean water. The specific implementation of the clean water collecting member is not limited in the present application.
[0177] The diameter of the water outlet channel 414 is much smaller than that of the water inlet channel 413, and the top end of the water outlet channel 414 can be connected to the clean water adapter pipe 3012 through a pipeline.
[0178] That is to say, the water collected by the clean water collecting member flows into the clean water collecting cavity 412 from the water inlet channel 413, and the clean water collecting cavity 412 is similar to a water storage groove. The water in the clean water collecting cavity 412 then flows into the clean water flow channel of the flow channel plate 3 through the water outlet channel 414 and the clean water adapter pipe 3012.
[0179] When the water in the clean water collecting cavity 412 of the clean water collecting member flows into the clean water collecting cavity 412, air bubbles will be generated. The air bubbles will float to the water surface, and the water outlet channel 414 is located at the bottom end of the clean water collecting cavity 412, and the water outlet channel 414 is relatively thin, so the air bubbles will not enter the water outlet channel 414. When the water flows into the clean water adapter pipe 3012 from the water outlet channel 414, and then flows into the clean water in the clean water flow channel, no air bubbles will be generated.
[0180] A liquid level sensor is also installed in the clean water collecting cavity 412 for sensing the liquid level of the clean water.
[0181] The back side of the collection plate 41 is also provided with a sewage passage 416, which extends to the top end of the collection plate 41 and communicates with a sewage adapter pipe 3014 through a pipe, the sewage adapter pipe 3014 communicates with the detection cavity, and the inner cover plate 42 is also provided with a liquid outlet 421 which communicates with the sewage passage 416. After the detection is completed, the mixed liquid in the detection cavity can flow into the sewage passage 416 from the sewage flow channel 302 of the flow channel plate 3, the sewage adapter pipe 3014, and then flow into the closestool from the sewage passage 416 and the liquid outlet 421.
[0182] In Figures 28-30 In another embodiment, the collector also includes a collection plate 41, an outer cover plate 43, an inner cover plate 42 and a clean water collection piece. Similarly, the collection plate 41 is also a round cake shape and is also provided with a clean water collection cavity 412 and a sample collection cavity 411. The top surface of the collection plate 41 is also provided with a water inlet passage 413, a water outlet passage 414 and a sample outlet passage 415.
[0183] The difference is that the sample collection cavity 411 and the clean water collection cavity 412 are formed by combining the collection plate 41, the inner cover plate 42 and the outer cover plate 43. The sample collection cavity 411 and the clean water collection cavity 412 are through grooves provided on the collection plate 41. After the front cover plate and the rear cover plate are combined on the front and rear sides of the collection plate 41, the front and rear sides of the sample collection cavity 411 and the clean water collection cavity 412 are closed to form the sample collection cavity 411 and the clean water collection cavity 412.
[0184] The volume of the clean water collection cavity 412 is greater than that of the sample collection cavity 411. The clean water collection cavity 412 and the sample collection cavity 411 are respectively arranged on the two sides of the collection plate 41, and a partition is arranged in the middle.
[0185] The top surface of the collection plate 41 is provided with a sample collection groove 401, which is recessed on the top surface of the collection plate 41.
[0186] The bottom wall of the sample collection groove 401 is also provided with a sampling passage, which is recessed from the bottom wall of the sample collection groove 401 to the sample collection cavity 411.
[0187] The sample outlet passage 415 is also recessed from the bottom wall of the sample collection groove 401 to the bottom of the sample collection cavity 411. The sample outlet passage 415 is located on the partition, and the top end of the sample outlet passage 415 is a vertical flow channel extending vertically upward, the middle region is a curved flow channel, and the bottom end is a horizontal passage extending to the bottom of the sample collection cavity. The curved design of the sample outlet passage 415 can also make the sample adhere to the inner wall of the sample outlet passage 415, and mix during the flow process to reduce air bubbles.
[0188] The bottom end of the sample collection cavity 411 is also provided with a sewage outlet 417, which is open towards the bottom end of the collection plate 41, and the excess sample can flow into the toilet from the sewage flow channel 302.
[0189] The water inlet channel 413 is also recessed from the bottom wall of the sample collection groove 401 to the clean water collection cavity 412, and the water inlet channel 413 is located on the front side of the collection plate 41. The top end of the water inlet channel 413 can be inserted into a pipe, which is in communication with the clean water collection member, and similar to the previous embodiment, it will not be repeated here.
[0190] The water outlet channel 414 is formed by the bottom of the clean water collection cavity 412 extending upwardly to the bottom wall of the sample collection groove 401, the water outlet channel 414 is recessed from the back side of the collection plate 41, and is also located on the isolation part, the water outlet channel 414 is also in the shape of a bend, which can reduce the bubbles in the clean water flow into the clean water flow channel of the flow channel plate 3 during the collection of clean water.
[0191] The back side of the isolation part is also provided with a sewage channel 416, the top end of the sewage channel 416 extends to the bottom wall of the sample collection groove 401 and is in communication with the sewage adapter pipe 3014 through a pipe, the bottom end of the sewage channel 416 is in communication with the liquid outlet 421 of the inner cover plate 42, the inner cover plate 42 covers the back side of the collection plate 41 and is used to attach to the inner wall of the toilet. The liquid in the detection cavity can flow into the sewage channel 416 from the sewage flow channel 302, the sewage adapter pipe 3014, and then flow into the toilet from the liquid outlet 421.
[0192] The collector also includes two liquid level sensors, which are installed in the clean water collection cavity 412 and the sample collection cavity 411 respectively, for sensing the liquid level of clean water and sample.
[0193] A sample flow channel can be provided on the flow channel plate 3, which is in direct communication with the sample collection cavity 411 through the sample adapter pipe 3011. In another embodiment, two sample flow channels can also be provided on the flow channel plate 3, the inner ends of the two sample flow channels are in communication with two circumferential holes 32 respectively, and the outer ends are in communication with two pipes through two sample adapter pipes 3011 respectively.
[0194] The two sample flow channels are defined as upper sample flow channel 341 and lower sample flow channel 342, and the pipes in communication with the two sample flow channels are upper sample pipe 344 and lower sample pipe 345 respectively. The upper sample flow channel 341 is in communication with the upper sample pipe 344 through the sample adapter pipe 3011, and the lower sample flow channel 342 is in communication with the lower sample pipe 345 through a sample adapter pipe 3011.
[0195] The lower sample pipe is communicated with the lower sample flow channel 342 at one end and with the sample outlet channel 415 of the sample collection cavity 411 at the other end, and a burette is arranged in the middle of the lower sample pipe, which is defined as the sample burette 343. The upper sample pipe is communicated with the upper sample flow channel 341 at one end and with the upper end of the sample burette 343 at the other end. When the sample needs to be extracted, the rotor 6 needs to be aligned with the circumferential hole 32 communicated with the upper sample flow channel 341, the air in the upper sample flow channel 341, the upper sample pipe and the sample burette 343 is extracted, and the negative pressure is formed in the sample burette 343, so that the sample can be dropped into the sample burette 343 from the sample collection cavity 411. Then the rotor 6 is rotated to align the middle transfer channel with the circumferential hole 32 of the lower sample flow channel 342, the air in the lower sample flow channel 342 and the lower sample pipe is extracted, and the liquid in the sample burette 343 flows into the lower sample flow channel 342 from the lower sample pipe. This arrangement can ensure that the sample is slowly dropped into the lower sample flow channel 342 and no air bubbles are generated.
[0196] Of course, in another embodiment, the exhaust hole 418 is arranged in the sample collection cavity 411, the upper sample flow channel 341 can be communicated with the exhaust hole 418, and the lower sample flow channel 342 is communicated with the sample outlet channel 415 of the sample collection cavity 411. At this time, the sample collection cavity 411 is similar to the sample burette described above, and the operation method is the same as above, which will not be described in detail.
[0197] The clear water flow channel of the flow channel plate 3 can also be provided, which is directly communicated with the clear water collection cavity 412.
[0198] Of course, the flow channel plate 3 is provided with two clear water flow channels, and the two clear water flow channels are the upper clear water flow channel 351 and the lower clear water flow channel 352, which have the same principle as the two sample flow channels described above. The outer ends of the two clear water flow channels are respectively communicated with the two circumferential holes 32. Similarly, the outer end of the lower clear water flow channel is communicated with the clear water transfer pipe 3012, and the clear water transfer pipe 3012 is communicated with the clear water collection cavity 412 through the upper clear water pipe 354. The lower clear water pipe 355 is also provided with a clear water burette 353. The upper clear water pipe 354 is communicated with the clear water burette 353 of the lower clear water pipe 355.
[0199] The upper clear water flow channel 351 is communicated with the clear water transfer pipe 3012, and the clear water transfer pipe 3012 is communicated with the upper end of the clear water burette 353 through the upper clear water pipe 354.
[0200] When the sample needs to be extracted, the rotor 6 needs to be aligned with the circumferential hole 32 communicating with the supernatant water channel 351, the air in the supernatant water channel 351, the supernatant water pipeline and the water titration tube 353 is extracted and a negative pressure is formed in the water titration tube, and the water can be dropped into the water titration tube 353 from the water collection cavity 412. Then the rotor 6 is rotated again, so that the transfer channel is aligned with the circumferential hole 32 of the lower supernatant water channel 352, the air in the lower supernatant water channel 352 and the lower supernatant water pipeline is extracted, and the liquid in the water titration tube 353 flows into the lower supernatant water channel 352 from the lower supernatant water pipeline. Such arrangement can ensure that the water slowly drops into the lower supernatant water channel 352 and no bubbles are generated.
[0201] The utility model still relates to a kind of control methods of urine test instrument 100, and the urine test instrument 100 includes reagent box 2, collector, rotary valve and the detection mechanism described above, reagent box 2 is same as above, be equipped with multiple reagent cavities 21, reagent is placed in the reagent cavity 21. Collector is also equipped with the sample collection cavity 411 and water collection cavity 412 described above. Rotary valve and the above consistent include microfluidic chip and rotor 6, microfluidic chip is also equipped with public channel 33, lower sample channel 342, upper sample channel 341, supernatant water channel 351, lower supernatant water channel 352, multiple reagent channels 37, detection channel 38, air channel 36 and transfer channel. The outer end of lower sample channel 342 is communicated with the sample collection cavity 411 by lower sample pipeline 345, and the lower sample pipeline 345 is equipped with sample titration tube 343. The outer end of upper sample channel 341 is communicated with the top end of sample titration tube 343. The outer end of multiple reagent channels 37 is respectively communicated with multiple reagent cavities 21. The outer end of lower supernatant water channel 352 is communicated with the water collection cavity 412. Rotor 6 is equipped with transfer channel, and transfer channel can be rotated when rotor 6 rotates, and the inner end 61 of transfer channel is located in the center of rotor 6 and is communicated with the inner end of public channel 33, and the outer end is rotated with rotor 6 and is communicated with the inner end of lower sample channel 342, upper sample channel, supernatant water channel 351, lower supernatant water channel 352, multiple reagent channels 37, detection channel 38 and air channel 36. That is, when rotary valve switches to lower sample channel 342, upper sample channel, supernatant water channel 351, lower supernatant water channel 352, multiple reagent channels 37, detection channel 38 and air channel 36 each time, transfer channel is communicated with lower sample channel 342, upper sample channel, supernatant water channel 351, lower supernatant water channel 352, multiple reagent channels 37, detection channel 38 and air channel 36.
[0202] Detection mechanism is same as above, and is equipped with detector and detection cavity, and detection cavity is communicated with detection channel 38, and detector is used for detecting sample in detection cavity.
[0203] As shown in Figure 31 The control method of urine test instrument 100 includes the following steps:
[0204] S1, the rotary valve switches to the upper sample flow channel 341, the transfer channel communicates with the upper sample flow channel 341, and air in the sample burette 343 is drawn into the transfer channel and the common flow channel 33, the sample burette 343 forms a negative pressure, and the sample in the sample collection cavity 411 enters the sample burette 343. The rotary valve switches to the upper sample flow channel, and the common passage communicates with the upper sample flow channel. Air in the sample burette 343 can be drawn into the common flow channel 33, so that the sample burette 343 forms a negative pressure. After the sample enters the sample burette 343, it flows into the bottom end of the sample burette 343 under the action of gravity.
[0205] S2, the rotary valve switches to the lower sample flow channel 342, the transfer channel communicates with the lower sample flow channel 342, and the sample in the sample burette 343 is drawn into the common flow channel 33 or the transfer channel. At this time, part of the sample enters the transfer channel, and most of the sample stays in the lower sample flow channel 342, which facilitates subsequent quantitative extraction.
[0206] S3, the rotary valve switches to the lower water flow channel 352, the transfer channel communicates with the lower water flow channel 352, and the water in the water collection cavity 412 is drawn into the common flow channel 33 or the transfer channel. Because the transfer channel and the common flow channel 33 communicate, in the case that the amount of sample and water entering the transfer channel is large, they can enter the common flow channel 33. The water and the sample entering the common flow channel 33 or the transfer channel are mixed.
[0207] S4, the sample and water in the common flow channel 33 are discharged from the outer end of the common flow channel 33. They can be discharged from the outer end of the common flow channel 33 or from the detection cavity, and the specific discharge method is not limited.
[0208] S5, the rotary valve switches to the lower sample flow channel 342, the transfer channel communicates with the lower sample flow channel 342, and the sample in the lower sample flow channel 342 is quantitatively extracted into the common flow channel 33 or the transfer channel. In step S2, the sample is drawn into the lower sample flow channel 342, and the sample in the lower sample flow channel 342 basically flows to the inner end of the lower sample flow channel 342, so the sample can be quantitatively extracted according to the length of time for extracting the sample.
[0209] S6, the rotary valve switches to the reagent flow channel 37, the transfer channel communicates with the reagent flow channel 37, and the reagent in the reagent cavity 21 is quantitatively extracted into the common flow channel 33 or the transfer channel. The reagent flow channel 37 always communicates with the reagent cavity 21, so part of the reagent in the reagent cavity 21 is located in the reagent flow channel 37 and can be directly quantitatively extracted.
[0210] S7, the rotary valve switches to the detection flow channel 38, the transfer channel communicates with the detection flow channel 38, and the sample and reagent in the common flow channel 33 or the transfer channel are pushed into the detection cavity.
[0211] S8, the detector detects the sample in the detection cavity.
[0212] The outer end of the transfer channel of the rotor communicates with different flow channels as the rotary valve switches, for example, the outer end of the transfer channel communicates with the reagent flow channel when the rotary valve switches to the reagent flow channel, and so on when the rotary valve switches to other flow channels, which will not be repeated here.
[0213] Further, the urine test instrument 100 comprises a first pump and a second pump, the first pump is the peristaltic pump 91 described above, and the second pump is the plunger pump 92. The first pump is connected with a first driving pipeline, and the first driving pipeline communicates with the outer end of the common flow channel 33. The second pump is connected with a second driving pipeline, and the second driving pipeline communicates with the outer end of the common flow channel 33.
[0214] In the above steps, in step S1, the first pump rotates forward to extract air in the sample burette 343.
[0215] In step S2, the first pump rotates forward to extract the sample in the sample burette 343 into the common flow channel 33.
[0216] In step S3, the first pump rotates forward to extract water in the water collection cavity 412 into the common flow channel 33.
[0217] In step S4, the first pump rotates forward to discharge the sample and water in the common flow channel 33 through the outer end of the first driving pipeline.
[0218] In step S5, the second pump rotates forward and quantitatively extracts the sample in the lower sample flow channel 342 into the common flow channel 33.
[0219] In step S6, the second pump rotates forward and quantitatively extracts the reagent in the reagent cavity 21 into the common flow channel 33.
[0220] In step S7, the second pump reverses to push the sample and reagent in the common flow channel 33 into the detection cavity.
[0221] That is, the first pump has a large stroke and can extract a large amount of water or sample, while the second pump is mainly responsible for quantitatively extracting the sample and reagent.
[0222] Optionally, the lower water flow channel 352 communicates with the water collection cavity 412 through a lower water pipeline 355, and the lower water pipeline 355 is provided with a water burette 353.
[0223] The rotary valve is provided with an upper clean water flow channel 351, and the clean water titration tube 353 is communicated with the upper clean water flow channel 351.
[0224] In step S3, the rotary valve is switched to the upper clean water flow channel 351, the transfer channel is communicated with the upper clean water flow channel 351, the first pump is rotated in a forward direction, and the air in the clean water titration tube 353 is pumped out, the clean water titration tube 353 forms a negative pressure, and the clean water in the clean water collection cavity 412 enters the clean water titration tube 353, then the rotary valve is switched to the lower clean water flow channel 352, and the first pump is rotated in a forward direction to pump the water in the clean water titration tube 353 into the lower clean water flow channel 352.
[0225] Optionally, before step S6, it is judged whether a plurality of reagents need to be pumped, if one reagent is needed, step S6 is performed, if a plurality of reagents are needed, step S6 is repeated, then the rotary valve is switched to the detection flow channel, the reagent and the sample in the transfer channel are pushed into the detection flow channel, then the rotary valve is switched to different reagent flow channels, different reagents are pumped into the transfer channel, and then the pumped reagents are pushed into the detection flow channel again.
[0226] That is, each time the rotary valve is switched to a different reagent flow channel, a reagent is pumped into the transfer channel, the rotary valve is switched to the detection flow channel, the reagent in the transfer channel is pushed into the detection flow channel and reacts with the sample, and then the rotary valve is switched to a different reagent flow channel after waiting for a few seconds or a preset time, different reagents are pumped into the detection flow channel to react with the sample, and the reaction time or waiting time is set as required. In some embodiments, the waiting time can also be not set.
[0227] Some detection items need one reagent to be completed, some items need two or more reagents, and the detection items requiring a plurality of reagents need to be repeated several times in step S6, and different reagents are pumped each time.
[0228] It should be understood that whether the detection item needs to be diluted, the amount of the diluted sample required for detection, and the type and amount of the reagent required are set in the control module, so after starting detection, the control module will determine the process according to the detection item.
[0229] Optionally, in step S5, after the second pump pumps the sample in the lower sample flow channel 342 into the common flow channel 33, the rotary valve is switched to the lower clean water flow channel 352, the second pump quantitatively pumps the water in the lower clean water flow channel 352 into the common flow channel 33 and mixes with the sample in the common flow channel 33 to dilute the sample. Some detection items need to mix the sample with clean water to dilute the sample, so after pumping the sample, a certain amount of clean water needs to be pumped.
[0230] In step S6, after the second pump is rotated to push the reagent in the reagent cavity 21 into the common flow channel 33, the rotating and cutting valve is switched to the air flow channel 36, and the second pump is rotated to suck air into the common flow channel 33.
[0231] Optionally, in step S5, after the second pump is rotated to suck water in the lower clear water flow channel 352 into the common flow channel 33 and mix with the sample in the common flow channel 33, the sample is diluted for 8-12 seconds. The dilution time is preferably 10 seconds.
[0232] As a preferred solution, the rotating and cutting valve is further provided with a mixing cavity 39, which is located on the path of the detection flow channel 38 and communicates with the detection flow channel 38.
[0233] In step S6, after the second pump is rotated to push the reagent in the reagent cavity 21 into the common flow channel 33, the rotating and cutting valve is switched to the air flow channel 36, and the second pump is rotated to suck air into the common flow channel 33. Due to the stroke problem, part of the air needs to be sucked.
[0234] In step S7, the rotating and cutting valve is switched to the detection flow channel 38, and the second pump is reversed to push the sample and the reagent in the common flow channel 33 into the mixing cavity 39.
[0235] The first pump is rotated for a predetermined time and then reversed for a predetermined time to continuously flow the reagent and the sample in the mixing cavity 39 and form a mixed liquid. The peristaltic pump 91 continuously flows the reagent and the sample in the mixing cavity 39 and mixes them.
[0236] Then the second pump is rotated to push the mixed liquid in the mixing cavity 39 into the detection cavity.
[0237] Further, the mixing cavity 39 includes a mixing bend 392 and a mixing chamber 391, which communicate with each other, and the mixing bend 392 is a curved flow channel.
[0238] In step S7, after the second pump is reversed to push the sample and the reagent in the common flow channel 33 into the mixing cavity 39, the first pump is rotated for a predetermined time and then reversed for a predetermined time to continuously flow the reagent and the sample in the mixing bend 392 and the mixing cavity 39 and form a mixed liquid.
[0239] Optionally, the rotary valve is in vertical state and is provided with a mixing cavity 39, which is located on the path of the detection flow channel 38 and communicates with the detection flow channel 38. The mixing cavity 39 has an inlet and an outlet, and the inlet is located below the outlet. The flow channel plate 3 is placed in vertical state, and the mixing cavity 39 is located above the common flow channel 33. The inlet of the mixing cavity 39 is below, and the outlet is above, which refers to the end opening to the detection cavity.
[0240] In step S6, after the second pump quantitatively draws the reagent in the reagent cavity 21 into the common flow channel 33, the rotary valve is switched to the air flow channel 36, and the second pump is positively rotated to quantitatively draw air into the common flow channel 33.
[0241] In step S7, the rotary valve is switched to the detection flow channel 38, the second pump is reversely rotated to push the sample and the reagent in the common flow channel 33 into the top end of the mixing cavity 39, the sample and the reagent move downward by gravity, then the first pump is reversely rotated for a preset time to push the sample and the reagent into the top end of the mixing cavity 39 again, then the first pump stops moving, and the sample and the reagent move to the bottom end of the mixing cavity 39 by gravity to form a continuous flow of mixed liquid.
[0242] Finally, the second pump is positively rotated to push the mixed liquid in the mixing cavity 39 into the detection cavity.
[0243] Preferably, after step S8, step S9 is further included: the rotary valve is switched to the lower clean water flow channel 352, the first pump is positively rotated to draw water in the lower clean water flow channel 352 into the common flow channel 33, then the rotary valve is switched to the detection flow channel 38, and the first pump is reversely rotated to push the water in the common flow channel 33 into the detection flow channel 38 and the detection cavity and then discharge. After the detection is completed, clean water is used to clean the detection cavity.
[0244] Optionally, after step S8, step S9 is further included: the rotary valve is switched to the lower clean water flow channel 352, the first pump is positively rotated to draw water in the lower clean water flow channel 352 into the common flow channel 33, then the rotary valve is switched to the air flow channel 36, the first pump is positively rotated to draw air, and then the water in the common flow channel 33 is discharged from the first driving pipe. After the detection is completed, clean water is used to clean the common flow channel 33 and the first driving pipe, the first driving pipe and the collector communicate, and waste liquid can be discharged from the collector into the toilet.
[0245] Optionally, after step S8, there is further a step S9: the rotary valve switches to communicate with the lower clean water flow channel 352, the first pump rotates forward to draw water in the lower clean water flow channel 352 into the common flow channel 33, then the rotary valve switches to communicate with the lower sample flow channel 342, the first pump rotates reversely to push the water in the common flow channel 33 into the lower sample pipeline 345 and out of the sample collection cavity 411. After the detection is completed, clean water is drawn again to clean the lower sample flow channel 342, the lower sample pipeline 345 and the sample collection cavity 411, and waste liquid is discharged from the sample collection cavity 411.
[0246] After the urine test instrument 100 is used for several months or operates a preset number of times, the reagents in the reagent kit 2 are used up, and the reagent kit 2 needs to be replaced. When the reagent kit 2 is replaced, the reagent flow channel 37 needs to be thoroughly cleaned, and the washing flow channel of the flow channel plate 3 needs to be used.
[0247] The urine test instrument 100 further comprises washing liquid and a washing cavity for containing the washing liquid.
[0248] The replacement of the reagent kit comprises the following steps:
[0249] S01: the rotary valve switches to the lower clean water flow channel 352, the first pump rotates forward to draw clean water into the common flow channel 33, then the rotary valve switches to the plurality of reagent flow channels 37 in sequence, and the first pump reverses in sequence to push the water in the common flow channel 33 into the plurality of reagent flow channels 37 in sequence and flow into the plurality of reagent cavities 21 from the plurality of reagent flow channels 37.
[0250] S02: replace the reagent kit 2.
[0251] After the reagent flow channel 37 is cleaned with clean water, waste liquid is pushed into the reagent cavities 21 of the reagent kit 2, and then the reagent kit 2 is replaced.
[0252] Optionally, before step S01, there is further a step:
[0253] the rotary valve switches to the lower clean water flow channel 352, the first pump rotates forward to draw clean water into the common flow channel 33, then the rotary valve switches to the air flow channel 36, the first pump rotates forward to draw air into the common flow channel 33, and clean water in the common flow channel 33 is discharged from the first driving pipeline;
[0254] the rotary valve switches to the lower clean water flow channel 352 again, the first pump rotates forward to draw clean water into the common flow channel 33, then the rotary valve switches to the lower sample flow channel 342, the first pump reverses to push the clean water in the common flow channel 33 into the lower sample pipeline 345 and out of the sample collection cavity 411;
[0255] The rotary valve switches to the lower clean water flow channel 352, the first pump is rotated to extract clean water into the common flow channel 33; then the rotary valve switches to the detection flow channel 38, the first pump is reversed to push the clean water in the common flow channel 33 into the detection flow channel 38, and is discharged from the detection cavity.
[0256] After the common flow channel 33, the sample collection cavity 411 and the detection cavity are washed by extracting clean water first, the reagent flow channel 37 is cleaned.
[0257] Optionally, before step S01, it further includes the following steps:
[0258] The rotary valve switches to the lower clean water flow channel 352, the first pump is rotated to extract clean water into the common flow channel 33; then the rotary valve switches to the detection flow channel 38, the first pump is reversed to push the clean water in the common flow channel 33 into the detection flow channel 38, and is discharged from the detection cavity.
[0259] Then the rotary valve switches to the detection flow channel 38, the first pump is reversed to suck the clean water and the washing liquid in the common flow channel 33 into the mixing cavity 39, then the first pump is rotated for a preset time, and then is reversed for a preset time, so that the clean water and the washing liquid in the mixing cavity 39 are continuously flowed and mixed into a diluted washing liquid, then the first pump is rotated to suck the diluted washing liquid in the mixing cavity 39 into the common flow channel 33.
[0260] The rotary valve switches to a plurality of reagent flow channels 37 in sequence, and the first pump is reversed to push the diluted washing liquid in the common flow channel 33 into a plurality of reagent cavities 21 in sequence.
[0261] After the common flow channel 33, the sample collection cavity 411 and the detection cavity are cleaned by clean water, the washing liquid and the clean water are repeatedly mixed into a diluted washing liquid, the reagent flow channel 37 is cleaned by the diluted washing liquid, and then step S01 is performed.
[0262] After the urine test instrument 100 operates for a preset period, for example, several months, the internal structure needs to be thoroughly cleaned, which includes the following steps:
[0263] S001: The rotary valve switches to the lower clean water flow channel 352, the first pump is rotated to extract clean water into the common flow channel 33; then the rotary valve switches to the detection flow channel 38, the first pump is reversed to push the clean water in the common flow channel 33 into the detection flow channel 38, and is discharged from the detection cavity.
[0264] S002: Then the rotary valve switches to the detection flow channel 38, the first pump reverses and sucks the clean water and washing liquid in the common flow channel 33 into the mixing cavity 39, then the first pump rotates forward for a preset time, reverses for a preset time, continuously flows and mixes the clean water and washing liquid in the mixing cavity 39 into diluted washing liquid, then the first pump rotates forward and sucks the diluted washing liquid in the mixing cavity 39 into the common flow channel 33. Diluted washing liquid is needed for thorough cleaning, so water and washing liquid are mixed first.
[0265] S003: The rotary valve switches to the lower sample flow channel 342, the first pump reverses and pushes the diluted washing liquid in the common flow channel 33 from the lower sample pipeline 345 into the sample collection cavity 411;
[0266] S004: Repeat S001 and S002, then the first pump reverses and pushes the diluted washing liquid in the common flow channel 33 into the detection cavity;
[0267] S005: After waiting for a preset time, the rotary valve switches to the lower clean water flow channel 352, the first pump rotates forward and quantitatively extracts clean water into the common flow channel 33, then pushes the clean water in the common flow channel 33 into the detection cavity, the first drive pipeline and the clean water collection cavity and discharges.
[0268] After the diluted washing liquid is soaked in the sample collection cavity 411 and the detection cavity for a preset time, it is discharged.
[0269] Optionally, step S005 comprises:
[0270] S0051: The rotary valve switches to the lower clean water flow channel 352, the first pump rotates forward and quantitatively extracts clean water into the common flow channel 33, then the rotary valve switches to the detection flow channel 38, the first pump reverses and pushes the clean water in the common flow channel 33 into the detection cavity and discharges;
[0271] S0052: The rotary valve switches to the lower clean water flow channel 352, the first pump rotates forward and quantitatively extracts clean water into the common flow channel 33, then the rotary valve switches to the air flow channel 36, the first pump rotates forward and extracts external air into the common flow channel 33, then the clean water in the common flow channel 33 is discharged from the first drive pipeline;
[0272] S0053: The rotary valve switches to the lower clean water flow channel 352, the first pump rotates forward and quantitatively extracts clean water into the common flow channel 33, then the rotary valve switches to the lower sample flow channel 342, the first pump reverses and pushes the clean water in the common flow channel 33 into the sample collection cavity 411 and discharges.
[0273] Firstly, water is pumped into the common flow channel 33, and then the dilute washing liquid is pushed out from the sample collection cavity 411, the detection cavity and the first driving pipeline by water.
[0274] Optionally, before step S001, the method further comprises the step of:
[0275] The rotary valve is switched to the lower clean water flow channel 352, the first pump is rotated to pump clean water into the common flow channel 33, then the rotary valve is switched to the air flow channel 36, the first pump is rotated to pump air into the common flow channel 33, and the clean water in the common flow channel 33 is discharged from the first driving pipeline;
[0276] The rotary valve is switched to the lower clean water flow channel 352, the first pump is rotated to pump clean water into the common flow channel 33, then the rotary valve is switched to the lower sample flow channel 342, the first pump is reversed to push the clean water in the common flow channel 33 into the lower sample pipeline 345, and the clean water is discharged from the sample collection cavity 411;
[0277] The rotary valve is switched to the lower clean water flow channel 352, the first pump is rotated to pump clean water into the common flow channel 33, then the rotary valve is switched to the detection flow channel 38, the first pump is reversed to push the clean water in the common flow channel 33 into the detection flow channel 38, and the clean water is discharged from the detection cavity.
[0278] The urine test instrument further comprises a control module, after step S8, that is, after the detection is completed, the detector sends the detection result to the control module, if the detection result is abnormal, the control module reopens steps S1 to S8; if the detection result is normal, the next detection item is performed.
[0279] Further, the urine test instrument further comprises a warning light, the warning light is connected with the control module;
[0280] After step S8, if the detection result is abnormal for two consecutive times, the control module controls the signal light to warn.
[0281] In addition, the control module is also connected with the liquid level sensors in the clean water collection cavity and the sample collection cavity.
[0282] Before step S1, the liquid level sensor in the sample collection cavity can send the liquid level signal in the sample collection cavity to the control module, if the liquid level meets the requirement, S1 is performed, if the liquid level does not meet the requirement, the process is ended.
[0283] Step S3 is also a step, the control module receives the liquid level of the liquid level sensor in the clean water collection cavity to determine whether the clean water liquid level meets the requirement, if the clean water liquid level meets the requirement, the next step is performed. If the clean water liquid level does not meet the requirement, the process is ended.
[0284] In addition, the urine test instrument further comprises a fingerprint module or a sensing module connected with the control module, and the operator can control the urine test instrument to start by fingerprint, or the sensing module senses the action of the operator and then transmits a signal to the control module to start operation.
[0285] The utility model also relates to a kind of usage methods of microfluidic chip, flow channel plate 3 is equipped with above-mentioned sample flow channel, reagent flow channel 37, detection flow channel 38, public flow channel 33, public flow channel 33 is operable with sample flow channel, reagent flow channel 37 and detection flow channel 38 communication. Mixing cavity 39 is located on the path of detection flow channel 38 and has an outlet and an inlet, and mixing cavity 39 includes mixing elbow 392 and mixing chamber 391.
[0286] The usage method of the microfluidic chip includes the following steps:
[0287] S11, drive the sample in the sample flow channel into the public flow channel 33;
[0288] S12, drive the reagent in the reagent flow channel 37 into the public flow channel 33;
[0289] S13, drive the sample and reagent in the public flow channel 33 from the detection flow channel 38 into the inlet of the mixing cavity 39, flow into the mixing chamber 391 after entering the mixing elbow 392 from the inlet of the mixing cavity 39, form a mixed liquid, and then drive the mixed liquid to flow into the detection flow channel 38 from the outlet of the mixing cavity 39 again.
[0290] The above-mentioned sample flow channel is in communication with the sample collection cavity, and the reagent flow channel 37 is in communication with the reagent cavity 21 containing the reagent, and the detection flow channel 38 is in communication with the detection cavity.
[0291] The public flow channel 33 can be in communication with the sample flow channel, the reagent flow channel 37 or the detection flow channel 38 through a three-way valve or other valve, and the air in the public flow channel 33 can be pumped out to form a negative pressure by using a peristaltic pump 91 or a plunger pump 92, and then the sample in the above-mentioned sample flow channel or the reagent in the reagent flow channel 37 is driven into the public flow channel 33.
[0292] Optionally, the mixing chamber 391 is located above the mixing elbow 392, and the inlet of the mixing cavity 39 is below the outlet of the mixing cavity 39;
[0293] In step S13, the sample and reagent in the common flow channel 33 are driven to flow from the detection flow channel 38 into the inlet of the mixing cavity 39, and then into the mixing chamber 391 after flowing into the mixing cavity 39 from the inlet of the mixing cavity 39. Then, the mixing liquid is driven to flow from the mixing chamber 391 into the mixing cavity 39, and finally the mixing liquid is driven to flow from the mixing cavity 39 into the detection flow channel 38 again and then out of the detection flow channel 38.
[0294] Optionally, the mixing chamber 391 is located above the mixing elbow 392. In step S3, the sample and reagent in the common flow channel 33 are driven to flow from the detection flow channel 38 into the inlet of the mixing cavity 39, and then into the mixing chamber 391 after flowing into the mixing cavity 39 from the inlet of the mixing cavity 39. Then, the mixing liquid is driven to flow from the mixing chamber 391 into the mixing cavity 39, and then the mixing liquid is driven to flow from the mixing cavity 39 into the detection flow channel 38 again and then out of the detection flow channel 38.
[0295] During the mixing of the sample and reagent, the residence time of 1s-2s can improve the mixing effect.
[0296] As a preferred solution, the mixing cavity 39 comprises a plurality of mixing elbows 392 and a plurality of mixing chambers 391, and the plurality of mixing elbows 392 and the plurality of mixing chambers 391 are arranged in an interval and communicate with each other.
[0297] In step S13, the sample and reagent in the common flow channel 33 are driven to flow from the detection flow channel 38 into the inlet of the mixing cavity 39, and then into the plurality of mixing elbows 392 and the plurality of mixing cavities 39, and finally the mixing liquid is driven to flow from the detection flow channel 38.
[0298] Further, the mixing elbow 392 is an S-shaped elbow and comprises at least two horizontal flow channels and at least one turning flow channel 394, and any one of the turning flow channels 394 is located at the two ends of the two horizontal flow channels.
[0299] The horizontal flow channel extends in the horizontal direction, and the turning flow channel 394 comprises a curved inner arc 395 and an outer arc 396, and the inner arc 395 and the outer arc 396 are both arc-shaped and the inner diameter of the inner arc 395 is smaller than the inner diameter of the outer arc 396.
[0300] Optionally, the inner wall of the mixing chamber 391 comprises a first arc surface 397 and a second arc surface 398 opposite to the first arc surface 397, and the first arc surface 397 and the second arc surface 398 are arc surfaces protruding outward.
[0301] Optionally, each mixing chamber 391 communicates with the horizontal flow channels of two mixing elbows 392, and the two horizontal flow channels are arranged radially symmetrically at the top end and the bottom end of the mixing chamber 391.
[0302] In step S13, the sample and reagent in the common flow channel 33 are driven to enter the inlet of the mixing cavity 39 from the detection flow channel 38, flow into the mixing chamber 391 after entering one of the mixing bends 392 from the inlet of the mixing cavity 39, and then flow into the other mixing bend 392 from the mixing cavity 39 to form the mixed liquid. After 1-2 seconds, the mixed liquid is driven to flow back into the mixing chamber 391 and then be discharged from the mixing bend 392.
[0303] In one embodiment, each mixing chamber has an inlet and an outlet, respectively, and the inlet and the outlet of each mixing cavity are in communication with the adjacent mixing bend, respectively, and the inlet of each mixing cavity is located above the outlet.
[0304] In step S13, after the sample and reagent enter the mixing cavity, they flow into the mixing cavity from one of the mixing bends through the adjacent inlet, and then flow into the other mixing bend from the outlet. The sample and reagent continuously flow in the mixing chambers and the mixing bends to form the mixed liquid.
[0305] The microfluidic chip can be placed in the vertical direction, that is, the sample and reagent flow from bottom to top without considering the influence of gravity, so that there is no residual problem in the mixing chamber.
[0306] Optionally, the flow channel plate 3 is further provided with a clean water flow channel, and the common flow channel 33 is in communication with the clean water flow channel through the middle transfer channel of the rotor 6.
[0307] After step S13, step S14 is further included: water in the clean water flow channel is driven to enter the common flow channel 33, and then the water in the common flow channel 33 is driven to enter the detection flow channel 38, and then enter the mixing cavity 39 from the inlet of the mixing cavity 39, and then enter the detection flow channel 38 again from the outlet of the mixing cavity 39, and then be discharged from the detection flow channel 38.
[0308] As a preferred solution, the flow channel plate 3 is further provided with a central hole 31 and a plurality of circumferential holes 32 arranged around the central hole 31. The central hole 31 penetrates the flow channel plate 3 and is in communication with the inner end of the common flow channel 33. The plurality of circumferential holes 32 are arranged along the circumference with the central hole 31 as the center. The inner end of the common flow channel 33 is in communication with the central hole 31, and the outer end is connected with the pump through the driving pipeline. The inner end of the sample flow channel is in communication with one of the circumferential holes 32. The inner end of the reagent flow channel 37 is in communication with one of the circumferential holes 32. The inner end of the detection flow channel 38 is in communication with one of the circumferential holes 32.
[0309] The central hole 31 is in communication with the inner end of the middle transfer channel of the rotor 6, and the outer end of the middle transfer channel can be in communication with any one of the circumferential holes 32 by rotating the rotor 6.
[0310] In step S11, the rotor 6 rotates, the middle passage is communicated with the sample flow channel through one of the circumferential holes 32, and the pump drives the air in the common flow channel 33 and the sample flow channel to be extracted, and the sample in the sample flow channel is extracted into the common flow channel 33.
[0311] In step S12, the rotor 6 rotates, the middle passage is communicated with the reagent flow channel 37 through one of the circumferential holes 32, and the pump drives the air in the common flow channel 33 and the reagent flow channel 37 to be extracted, and the sample in the reagent flow channel 37 is extracted into the common flow channel 33.
[0312] In step S13, the rotor 6 rotates, the middle passage is communicated with the detection flow channel 38 through one of the circumferential holes 32; the pump drives the sample and the reagent in the common flow channel 33 to enter the inlet of the mixing cavity 39 from the detection flow channel 38, to flow into the mixing chamber 391 from the inlet of the mixing cavity 39 after entering the mixing bend 392, to form a mixed liquid, and then to drive the mixed liquid to flow into the detection flow channel 38 again from the outlet of the mixing cavity 39 and flow out from the detection flow channel 38.
[0313] As another preferred solution, the flow channel plate 3 is provided with two sample flow channels, which are an upper sample flow channel 341 and a lower sample flow channel 342. The inner ends of the lower sample flow channel 342 and the upper sample flow channel 341 are respectively communicated with two circumferential holes 32. The lower sample flow channel is communicated with the sample collection cavity containing the sample through the lower sample pipeline, and the lower sample pipeline is provided with the sample titration tube.
[0314] In step S11, the rotor 6 rotates, the outer end 62 of the middle passage is aligned with the circumferential hole 32 communicated with the upper sample flow channel 341, and the pump cooperates to drive the pipeline to extract the air in the common flow channel 33, the middle passage, the upper sample flow channel 341 and the sample titration tube.
[0315] Then the rotor 6 rotates, the outer end 62 of the middle passage is aligned with the circumferential hole 32 communicated with the lower sample flow channel 342, and the sample in the sample collection cavity is extracted from the lower sample flow channel 342 to the common flow channel 33.
[0316] The sample titration tube is arranged, which can reduce the air bubbles in the sample collection cavity flowing into the sample flow channel.
[0317] Optionally, the flow channel plate 3 is also provided with a clean water flow channel, which is communicated with one of the circumferential holes 32.
[0318] After step S13, there is further step S14: the rotor 6 rotates, the middle transfer channel is communicated with the upper clear water flow channel 351 through one of the circumferential holes 32, the pump drives the water in the clear water flow channel to enter the common flow channel 33, then drives the water in the common flow channel 33 to enter the detection flow channel 38, then from the inlet of the mixing cavity 39 to enter the mixing cavity 39, and then from the outlet of the mixing cavity 39 to enter the detection flow channel 38 again, and then discharged from the detection flow channel 38.
[0319] Preferably, the flow channel plate 3 is provided with an upper clear water flow channel 351 and a lower clear water flow channel 352, the inner end of the upper clear water flow channel 351 and the inner end of the lower clear water flow channel 352 are communicated with two circumferential holes 32 respectively. The lower clear water flow channel is communicated with a clear water collection cavity containing water through a lower clear water pipeline, and a clear water titration tube is arranged on the lower clear water pipeline. The upper clear water flow channel 351 is communicated with the clear water titration tube through an upper clear water pipeline.
[0320] After step S13, there is further step S14: the rotor 6 rotates, the middle transfer channel is communicated with the upper clear water flow channel 351 through one of the circumferential holes 32, the pump drives the water in the clear water flow channel to enter the common flow channel 33, then drives the water in the common flow channel 33 to enter the detection flow channel 38, then from the inlet of the mixing cavity 39 to enter the mixing cavity 39, and then from the outlet of the mixing cavity 39 to enter the detection flow channel 38 again, and then discharged from the detection flow channel 38.
[0321] Then the rotor 6 rotates, the outer end 62 of the middle transfer channel is aligned with the circumferential hole 32 communicated with the lower clear water flow channel 352, and the clear water in the clear water collection cavity is pumped from the lower clear water flow channel 352 to the common flow channel 33, the rotor 6 rotates, the common flow channel 33 is aligned with the circumferential hole 32 communicated with the detection flow channel 38, and the water in the common flow channel 33 is sequentially detected by the detection flow channel 38, and then discharged from the detection flow channel 38.
[0322] Optionally, the flow channel plate 3 is further provided with an air flow channel 36, and the inner end of the air flow channel 36 is communicated with the other circumferential hole 32.
[0323] Step S13, the rotor 6 rotates, before the middle transfer channel is communicated with the detection flow channel 38 through one of the circumferential holes 32; the rotor 6 rotates, so that the middle transfer channel is aligned with the circumferential hole 32 communicated with the air, so that the common flow channel 33 is communicated with the air flow channel 36, and the pump extracts air from the air flow channel 36 into the common flow channel 33.
[0324] Then the rotor 6 rotates, the middle transfer channel is communicated with the detection flow channel 38 through one of the circumferential holes 32; the pump drives the sample and reagent in the common flow channel 33 to enter the inlet of the mixing cavity 39 from the detection flow channel 38, and then flows into the mixing chamber 391 after entering the inlet of the mixing cavity 39, forms a mixed liquid, and then drives the mixed liquid to flow into the detection flow channel 38 again from the outlet of the mixing cavity 39, and then flows out from the detection flow channel 38.
[0325] The flow channel plate 3 of this invention can also be adapted to other urine analyzers 100. By configuring the pump or rotor 6 mentioned above, the sample and reagent can be mixed in the flow channel plate 3, reducing air bubbles and increasing the accuracy of the test.
[0326] The preferred embodiments of the present invention have been described in detail above, but it should be understood that, if necessary, aspects of the embodiments can be modified to utilize aspects, features, and concepts from various patents, applications, and publications to provide other embodiments.
[0327] In light of the detailed description above, these and other changes can be made to the embodiments. Generally, the terminology used in the claims should not be considered limited to the specific embodiments disclosed in the specification and claims, but should be understood to include all possible embodiments together with the full scope of equivalents enjoyed by these claims.
[0328] Those skilled in the art will understand that the above embodiments are specific examples of implementing the present invention, and in practical applications, various changes can be made to them in form and detail without departing from the spirit and scope of the present invention.
Claims
1. A reagent kit, characterized in that, The reagent kit is a flat plate with multiple reagent chambers and multiple flow channels, and one end of each of the reagent chambers is connected to one of the flow channels.
2. The reagent kit according to claim 1, characterized in that, The plurality of flow channel holes are arranged at intervals around a horizontal axis.
3. The reagent kit according to claim 2, characterized in that, The plurality of reagent chambers extend vertically and are arranged along a first direction, and the bottom ends of the plurality of reagent chambers are respectively connected to the plurality of flow channel holes.
4. The reagent kit according to claim 2, characterized in that, The reagent kit has a front side and a rear side that are positioned opposite to each other; The bottom walls of the plurality of reagent chambers include inclined surfaces and vertical surfaces, the height of which gradually decreases from back to front; The top surface of the vertical surface is connected to the front end of the inclined surface; The plurality of flow channel holes are formed by recesses from the rear side of the kit into the vertical surface.
5. The reagent kit according to claim 4, characterized in that, The kit also has multiple sealing grooves, which are formed by recesses on the rear side of the kit; The plurality of flow channel holes are formed by the inner wall of the plurality of sealing grooves recessed into the vertical surface.
6. The reagent kit according to claim 5, characterized in that, The reagent chamber opens toward the top of the reagent kit.
7. A testing device, characterized in that, The detection equipment includes: First shell, The kit according to claim 1; The flow channel plate is located within the first housing and is provided with: A central hole, which penetrates the flow channel plate and is located on a horizontal axis; A common flow channel, the inner end of which is connected to the central hole; Multiple circumferential holes, wherein the multiple circumferential holes are arranged at intervals around the central hole and are located on the same circumference; A sample flow channel, the inner end of which communicates with one of the circumferential holes, and the outer end of which communicates with a collection cavity located outside the first housing; and Multiple reagent channels, wherein the multiple reagent channels are respectively connected to multiple circumferential holes and multiple channel holes; The detection channel has an inner end connected to one of the circumferential holes and an outer end connected to the acquisition cavity. The rotor is rotatably mounted inside the first housing and has a transfer channel. The inner end of the transfer channel is connected to the central hole, and the outer end is operably connected to any one of the circumferential holes as the rotor rotates.
8. The detection device according to claim 7, characterized in that, The detection device also includes a detection plate, a portion of which is located within the first housing and has a detection cavity, which is connected to the common flow channel.
9. A urine analyzer, characterized in that, The urine analyzer includes: A second housing, detachably connected to the first housing; and The detection device as described in claim 7; A drive unit located in the second housing and detachably connected to the rotor, the drive unit being operable to drive the rotor to rotate; The collector has a collection chamber that is connected to the sample flow channel; The pump is located within the second housing and connected to the common flow channel via a drive pipe; The detection mechanism includes a detector and a detection plate. The detection plate has a detection cavity that is connected to the detection flow channel. The detector is used to detect the liquid in the detection cavity.
10. A toilet, characterized in that, The toilet includes the urine analyzer as described in claim 9.