Microplate reader constant-temperature and constant-humidity reaction cabin with self-adaptive environment temperature control function
By introducing a transmission screw and auxiliary components into the constant temperature and humidity reaction chamber of the ELISA reader, the problem of inconvenient removal of ELISA plates in the existing technology has been solved, realizing convenient and stable removal of ELISA plates, maintaining the temperature stability inside the chamber, and improving the convenience and consistency of experimental operations.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-04-23
- Publication Date
- 2026-03-31
AI Technical Summary
Existing ELISA assay chambers require inserting the plate into the chamber when removing it, making it inconvenient to retrieve plates located deep within the chamber and affecting experimental consistency.
A constant temperature and humidity reaction chamber for an ELISA reader with adaptive environmental temperature control was designed. It adopts a transmission screw, a transmission slider and auxiliary components. The transmission screw drives the reaction partition to move. Combined with the design of clamping plate and connecting spring, the ELISA plate can be stably and easily removed. The chamber door design prevents heat loss.
This allows for easy removal of the enzyme-labeled plate from the inside of the reaction chamber while maintaining constant temperature and humidity, reducing the impact of temperature fluctuations on other plates and improving the ease of operation and consistency of the experiment.
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Figure CN224066809U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of biological detection device technology, and in particular to a constant temperature and humidity reaction chamber for an enzyme-linked immunosorbent assay (ELISA) reader with adaptive environmental temperature control. Background Technology
[0002] Microplate readers typically have a reaction chamber for placing microplates for testing. The reaction chamber (or reaction tank, sample chamber) of the microplate reader can be integrated with the microplate reader itself or separate. In the current technology, when the reaction chamber is opened to remove the sample, the sample in the reaction chamber is exposed to the outside environment, and the temperature inside the reaction chamber will drop rapidly, which will cause batch-to-batch differences between different experiments.
[0003] The existing announcement number CN217731197U discloses a constant temperature reaction chamber for ELISA detection, including a constant temperature chamber with a temperature and humidity controller installed on the top for monitoring and adjusting the temperature and humidity inside the chamber. The chamber has several reaction partitions with reaction stations evenly distributed on them. An insulated door is hinged to the front of the chamber, and a retrieval window is opened on the front of the door at a position corresponding to a reaction station. A sealing door is hinged to the retrieval window. When it is necessary to remove the ELISA plate from the reaction station, the operator only needs to open the sealing door of the corresponding ELISA plate to remove it through the retrieval window. Because only one sealing door is opened, rapid convection between the warm air inside the chamber and the outside air is prevented, avoiding rapid temperature loss and minimizing the impact on other samples.
[0004] However, when using the above-mentioned constant temperature reaction chamber for ELISA detection, it is necessary to reach into the reaction chamber to retrieve the enzyme-labeled plate. When the reaction chamber is deep, it is inconvenient to retrieve the enzyme-labeled plate located inside the reaction chamber. Utility Model Content
[0005] The purpose of this invention is to provide a constant temperature and humidity reaction chamber for an ELISA reader with adaptive environmental temperature control, which solves the problem that when using existing constant temperature reaction chambers for ELISA detection, it is necessary to reach into the reaction chamber to retrieve the ELISA plates, and when the reaction chamber is deep, it is inconvenient to retrieve the ELISA plates located inside the reaction chamber.
[0006] To achieve the above objectives, this utility model provides a constant temperature and humidity reaction chamber for an enzyme-linked immunosorbent assay (ELISA) reader with adaptive environmental temperature control, comprising a chamber body, a door, and a reaction partition. The door is hinged to the chamber body and located on one side of the chamber body, and also includes a retrieval component.
[0007] The picking assembly includes a lead screw, a sliding block, a guide block, and an auxiliary component. The lead screw is rotatably connected to the chamber and is located inside the chamber. The sliding block is connected to the lead screw. The reaction partition is connected to the sliding block and is located on top of the sliding block. The guide block is fixedly connected to the reaction partition and slidably connected to the chamber. The auxiliary component is connected to the reaction partition.
[0008] The auxiliary components include clamping plates and connecting springs. The top of the reaction partition has multiple mounting slots, and two clamping plates are arranged opposite each other in each mounting slot. Multiple connecting springs are arranged between the clamping plates and the reaction partition.
[0009] The auxiliary component further includes a connecting rod, and the connecting rod is fixedly connected to the side of each clamping plate near the connecting spring. The connecting rod is slidably connected to the reaction partition.
[0010] The constant temperature and humidity reaction chamber of the ELISA reader with adaptive environmental temperature control also includes a retrieval door and a handle. The retrieval door is hinged to the chamber door and is located on the side of the chamber door closer to the reaction partition. The handle is fixedly connected to the retrieval door and is located on the side of the retrieval door away from the chamber door.
[0011] The constant temperature and humidity reaction chamber of the ELISA reader with adaptive environmental temperature control also includes an observation window, which is fixedly connected to the retrieval door and located on the surface wall of the retrieval door.
[0012] This invention relates to a constant temperature and humidity reaction chamber for an ELISA reader with adaptive environmental temperature control. The ELISA reaction is performed inside the chamber, which is closed by a door. A reaction partition is used to hold the ELISA plates. When it is necessary to remove the ELISA plates inside the chamber, the transmission screw is activated, causing the transmission slider to move outward, which in turn moves the reaction partition outward. A guide block guides the reaction partition during its movement, ensuring its stable movement. An auxiliary component stabilizes the ELISA plates on the reaction partition, facilitating the removal of the inner ELISA plates. The invention is convenient and simple to use. Attached Figure Description
[0013] To more clearly illustrate the technical solutions in the embodiments of this application or the prior art, the accompanying drawings used in the description of the embodiments or the prior art will be briefly introduced below.
[0014] Figure 1 This is a schematic diagram of the overall structure of the constant temperature and humidity reaction chamber of the ELISA reader with adaptive environmental temperature control according to the first embodiment of this utility model.
[0015] Figure 2This is a schematic diagram of the structure inside the cabin of the first embodiment of this utility model.
[0016] Figure 3 This is a schematic diagram of the auxiliary component of the first embodiment of the present invention.
[0017] Figure 4 This is the utility model Figure 3 Enlarged view of point A.
[0018] In the diagram: 101-hull, 102-door, 103-reaction partition, 104-transfer screw, 105-transfer slider, 106-guide block, 107-clamping plate, 108-connecting spring, 109-connecting rod, 110-access door, 111-handle, 112-observation window, 113-mounting slot. Detailed Implementation
[0019] The embodiments of the present invention are described in detail below. Examples of the embodiments are shown in the accompanying drawings. The embodiments described below with reference to the accompanying drawings are exemplary and intended to explain the present invention, but should not be construed as limiting the present invention.
[0020] The first embodiment of this application is as follows:
[0021] Please see Figures 1 to 4 ,in, Figure 1 This is a schematic diagram of the overall structure of the constant temperature and humidity reaction chamber of the ELISA reader with adaptive environmental temperature control according to the first embodiment of this utility model. Figure 2 This is a structural diagram of the cabin 101 in the first embodiment of this utility model. Figure 3 This is a schematic diagram of the auxiliary component of the first embodiment of the present invention. Figure 4 This is the utility model Figure 3 Enlarged view of point A.
[0022] This invention provides a constant temperature and humidity reaction chamber for an ELISA reader with adaptive environmental temperature control: it includes a chamber body 101, a door 102, a reaction partition 103, a retrieval assembly, a retrieval door 110, a handle 111, and an observation window 112. The retrieval assembly includes a transmission screw 104, a transmission slider 105, a guide block 106, and auxiliary components. The auxiliary components include a clamping plate 107, a connecting spring 108, and a connecting rod 109. The aforementioned solution solves the problem that when using existing constant temperature reaction chambers for ELISA detection, it is necessary to reach into the reaction chamber to retrieve the ELISA plates. When the reaction chamber is deep, it is inconvenient to retrieve the ELISA plates located inside the reaction chamber. It is understood that the aforementioned solution can also be used to solve the problem of stable placement.
[0023] In this specific embodiment, the hatch 102 is hinged to the cabin body 101 and located on one side of the cabin body 101. The hatch 102 closes the cabin body 101, and a sealing gasket is provided between the hatch 102 and the cabin body 101 to prevent heat loss. A dehumidifier and a temperature regulation device, such as a heater or a cooler, are provided inside the cabin body 101 to realize the adaptive environmental temperature control function of the cabin body 101, and to maintain constant temperature and humidity for enzyme labeling reactions. This is prior art and will not be described in detail here.
[0024] The transmission screw 104 is rotatably connected to the chamber 101 and located inside the chamber 101. The transmission slider 105 is connected to the transmission screw 104. The reaction partition 103 is connected to the transmission slider 105 and located on top of the transmission slider 105. The guide block 106 is fixedly connected to the reaction partition 103 and slidably connected to the chamber 101. The auxiliary component is connected to the reaction partition 103. The number of transmission screws 104 is multiple, and they are arranged in pairs on both sides of the chamber 101 and distributed along the height of the chamber 101. Each pair of corresponding transmission screws 104 is driven to rotate by a synchronous motor. The transmission slider 105 is threadedly engaged with the transmission screws 104 and moves with the rotation of the transmission screws 104. The reaction partition 103 adopts the reaction partition 103 disclosed in CN217731197U, which is a mesh plate with diamond-shaped or honeycomb mesh, which can improve the air flow efficiency in the chamber 101 and make the temperature in the chamber 101 uniform. The reaction partition 103 is bolted to the transmission slider 105 and moves out of the chamber 101 with the movement of the transmission slider 105. The auxiliary components are installed on the reaction partition 103.
[0025] Secondly, the top of the reaction partition 103 has multiple mounting slots 113, and two clamping plates 107 are arranged opposite each other in each mounting slot 113. Multiple connecting springs 108 are arranged between the clamping plates 107 and the reaction partition 103. The mounting slots 113 are used to place the ELISA plate, so that the ELISA plate is placed between the two clamping plates 107. The elastic force of the connecting springs 108 pushes the clamping plates 107 to clamp the two sides of the ELISA plate, ensuring the stability of the ELISA plate.
[0026] Meanwhile, each clamping plate 107 is fixedly connected to a connecting rod 109 on the side near the connecting spring 108, and the connecting rod 109 is slidably connected to the reaction partition 103. The connecting rod 109 pulls the clamping plate 107 to move. When it is necessary to remove the enzyme labeling plate, simply pull the connecting rod 109 to move the clamping plate 107 away from the enzyme labeling plate. The operation is simple and convenient.
[0027] Additionally, the retrieval door 110 is hinged to the hatch 102 and located on the side of the hatch 102 closer to the reaction partition 103. The handle 111 is fixedly connected to the retrieval door 110 and located on the side of the retrieval door 110 away from the hatch 102. Multiple retrieval doors 110 are provided to cooperate with multiple longitudinally distributed reaction partitions 103. When the retrieval door 110 is opened, the corresponding reaction partition 103 is exposed, allowing for retrieval. Since only one retrieval door 110 is opened, rapid convection between the warm air inside the cabin 101 and the outside air is avoided, preventing rapid temperature loss inside the cabin 101 and minimizing the impact on other samples. The retrieval door 110 and the hatch 102 are magnetically closed, making operation simple and convenient. The handle 111 allows for easy hand operation to open the retrieval door 110.
[0028] Finally, the observation window 112 is fixedly connected to the retrieval door 110 and is located on the surface wall of the retrieval door 110. The observation window 112 is made of transparent material and is set on the retrieval door 110 to facilitate observation of the reaction inside the cabin 101, making it more convenient to use.
[0029] Using the constant temperature and humidity reaction chamber of the ELISA reader with adaptive environmental temperature control according to this embodiment, when in use, the ELISA plate is placed on the mounting slot 113. At this time, the clamping plate 107 is clamped on both sides of the ELISA plate under the thrust of the connecting spring 108, limiting and fixing it. The chamber door 102 is closed, and the constant temperature and humidity reaction is achieved in the chamber body 101. When it is necessary to remove the ELISA plate, the corresponding removal door 110 is opened, and the corresponding transmission screw 104 is started to rotate, driving the transmission slider 105 to move, thereby driving the reaction partition 103 to move out of the chamber body 101. After moving to a position that is easy to remove, the corresponding connecting rod 109 is pulled to move the clamping plate 107 away from the ELISA plate, and the ELISA plate can be easily removed. Even if the chamber body 101 is deep, the ELISA plate placed at the rear can be easily removed, making it convenient and quick to use.
[0030] The above-disclosed embodiments are merely one or more preferred embodiments of this application and should not be construed as limiting the scope of this application. Those skilled in the art can understand that all or part of the processes for implementing the above embodiments and equivalent changes made in accordance with the claims of this application still fall within the scope of this application.
Claims
1.An enzyme label instrument constant temperature and humidity reaction cabin with adaptive environmental temperature control, comprising a cabin body, a cabin door and a reaction partition plate, the cabin door is hinged to the cabin body and located on one side of the cabin body, characterized in that, It also includes a taking assembly; The taking assembly includes a transmission screw rod, a transmission sliding block, a guide block and an auxiliary component, the transmission screw rod is rotationally connected with the cabin body and located inside the cabin body, the transmission sliding block is connected with the transmission screw rod, the reaction partition plate is connected with the transmission sliding block and located on the top of the transmission sliding block, the guide block is fixedly connected with the reaction partition plate and slidably connected with the cabin body, and the auxiliary component is connected with the reaction partition plate. 2.The enzyme label instrument constant temperature and humidity reaction cabin with adaptive environmental temperature control according to claim 1, characterized in that, The auxiliary component includes a clamping plate and a connecting spring, the top of the reaction partition plate is provided with a plurality of mounting grooves, two clamping plates are oppositely arranged in each mounting groove, and a plurality of connecting springs are arranged between the clamping plates and the reaction partition plate. 3.The enzyme label instrument constant temperature and humidity reaction cabin with adaptive environmental temperature control according to claim 2, characterized in that, The auxiliary component further includes a connecting rod, and the side of each clamping plate close to the connecting spring is fixedly connected with the connecting rod, and the connecting rod is slidably connected with the reaction partition plate. 4.The enzyme label instrument constant temperature and humidity reaction cabin with adaptive environmental temperature control according to claim 1, characterized in that, The enzyme label instrument constant temperature and humidity reaction cabin with adaptive environmental temperature control further includes a taking door and a handle, the taking door is hinged to the cabin door and located on the side of the cabin door close to the reaction partition plate, and the handle is fixedly connected with the taking door and located on the side of the taking door away from the cabin door. 5.The enzyme label instrument constant temperature and humidity reaction cabin with adaptive environmental temperature control according to claim 4, characterized in that, The enzyme label instrument constant temperature and humidity reaction cabin with adaptive environmental temperature control further includes an observation window, and the observation window is fixedly connected with the taking door and located on the surface wall of the taking door.
Citation Information
Patent Citations
Constant-temperature reaction box for ELISA (enzyme-linked immunosorbent assay) detection
CN217731197U