Nucleic acid amplification detection equipment with multi-channel reagent distribution structure

The automated stirring mechanism driven by a servo motor and the design of multiple reaction chambers solve the problem of insufficient contact between nucleic acid samples and reagents, achieving efficient and accurate nucleic acid amplification detection and improving the stability and detection efficiency of the equipment.

CN224077395UActive Publication Date: 2026-04-03JIANGSU BIO-HYKON BIOLOGICAL TECH CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-04-22
Publication Date
2026-04-03

AI Technical Summary

Technical Problem

In existing nucleic acid amplification and detection equipment, insufficient contact between nucleic acid samples and reagents leads to low amplification and detection efficiency and inaccurate results. Manual stirring is inefficient and difficult to control precisely.

Method used

An automated stirring mechanism driven by a servo motor is used to rotate the sample and reagent in the reaction chamber via a support platform. Combined with a multi-reaction chamber design and an electromagnetic block connection mechanism, it achieves precise reagent dispensing and thorough mixing of the sample and reagent.

Benefits of technology

It has improved the efficiency and accuracy of nucleic acid testing, reduced reagent waste and duplicate testing, lowered testing costs and labor intensity, and enhanced equipment stability and reliability.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of nucleic acid amplification detection, in particular to nucleic acid amplification detection equipment with a multi-channel reagent distribution structure, which comprises a bottom plate, four supporting columns are arranged below the bottom plate, a servo motor is fixedly arranged among the four supporting columns, a protective cover is arranged on the periphery above the bottom plate, and the protective cover is arranged on the bottom plate. A through round hole is formed in the position, corresponding to the output end of the servo motor, of the bottom plate, a first control box is installed at the bottom of the bottom plate and connected with the servo motor, and a stirring assembly is installed over the bottom plate and used for fully fusing a nucleic acid sample to be detected and a reagent; the upper end of the protective cover is provided with a fixing assembly, and the fixing assembly is used for fixing the stirring assembly. The utility model aims to solve the problems of insufficient contact between a nucleic acid sample and a reagent and low amplification detection efficiency of nucleic acid amplification detection equipment with a multi-channel reagent distribution structure.
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Description

Technical Field

[0001] This utility model relates to the field of nucleic acid amplification and detection technology, and in particular to a nucleic acid amplification and detection device with a multi-channel reagent dispensing structure. Background Technology

[0002] In the field of nucleic acid testing, nucleic acid amplification detection equipment is a key device used for the detection and analysis of nucleic acid samples. With the increasing demand for nucleic acid testing, higher requirements are being placed on the performance and efficiency of nucleic acid amplification detection equipment. During the nucleic acid amplification detection process, the nucleic acid sample to be tested needs to be thoroughly mixed with reagents to ensure the accuracy and reliability of subsequent amplification reactions.

[0003] In existing technologies, the commonly used mixing method relies primarily on manual operation, requiring staff to mix each nucleic acid sample individually. This operational mode is extremely simplistic and inefficient, not only making it difficult to precisely control the mixing intensity but also resulting in very low work efficiency. The drawbacks of manual mixing become even more pronounced when faced with batch testing tasks for nucleic acid samples. Staff are required to perform repetitive, monotonous, and heavy operations for extended periods, leading to a huge workload and a high risk of fatigue and errors. More importantly, due to the limitations of manual mixing, it is difficult to ensure that nucleic acid samples and reagents are thoroughly and evenly mixed in a short time. In practice, the degree of mixing varies among different samples, and some nucleic acid samples may not have sufficient contact with the reagents. This is similar to reactants not fully contacting each other in a chemical reaction, which severely affects the amplification process. Insufficient amplification directly reduces the efficiency of amplification detection. A testing task that could have been completed in a shorter time may require extended testing time due to uneven mixing of samples and reagents, increasing testing costs. Meanwhile, this insufficient mixing can seriously affect the accuracy of the detection results, impacting the efficiency of amplification detection and the accuracy of the results, resulting in poor practicality. Therefore, this utility model discloses a nucleic acid amplification detection device with a multi-channel reagent dispensing structure to solve the problems of insufficient contact between nucleic acid samples and reagents and low amplification detection efficiency in nucleic acid amplification detection devices with multi-channel reagent dispensing structures. Utility Model Content

[0004] In view of this, the purpose of this utility model is to propose a nucleic acid amplification detection device with a multi-channel reagent dispensing structure, so as to solve the problems of insufficient contact between nucleic acid samples and reagents and low amplification detection efficiency in nucleic acid amplification detection devices with multi-channel reagent dispensing structures.

[0005] To achieve the above objectives, this utility model provides a nucleic acid amplification detection device with a multi-channel reagent dispensing structure, comprising: a base plate, four support columns installed below the base plate, and a servo motor fixedly installed between the four support columns; a protective cover installed around the top of the base plate; a through-hole on the base plate corresponding to the output end of the servo motor; a first control box installed at the bottom of the base plate, the first control box being connected to the servo motor; a stirring assembly installed directly above the base plate, the stirring assembly being used to fuse the nucleic acid sample to be detected with the reagent; and a fixing assembly provided at the upper end of the protective cover, the fixing assembly being used to fix the stirring assembly.

[0006] Preferably, a U-shaped mounting bracket is installed on the side wall of the base plate, with the other end of the U-shaped mounting bracket located directly above the base plate. A cylinder is installed on the U-shaped mounting bracket located directly above the base plate, and a second control box is installed on the side wall of the U-shaped mounting bracket. A first electromagnetic block is installed at the lower output end of the cylinder, and a second electromagnetic block is magnetically attached to the other end of the first electromagnetic block. A reagent storage box is fixedly installed at the other end of the second electromagnetic block.

[0007] Preferably, the second control box is electrically connected to the second electromagnetic block.

[0008] Preferably, the stirring assembly includes a support platform, which is rotatably mounted on the upper surface of the base plate, and the bottom of the support platform is mounted on the output end of the servo motor. A support plate is provided on the upper surface of the support platform, and four guide posts are installed at the four corners of the lower surface of the support plate. A guide hole is provided on the upper surface of the support platform corresponding to the position of each guide post, and the guide post is slidably inserted into the guide hole. Multiple sets of grooves are provided on the upper surface of the support platform, and reaction chamber test tubes are inserted into each of the multiple sets of grooves. A sealing ring is installed on the upper part of the inner wall of each reaction chamber test tube, and a sealing ring is provided on the support plate corresponding to the position of each set of reaction chamber test tubes. The reaction chamber test tubes have circular holes of the same diameter, and a supporting ring is provided on the outer wall of the test tube corresponding to the position of the supporting plate. The bottom of the supporting ring is installed against the upper end face of the supporting plate. A loading plate is provided directly above the supporting plate, and a reagent dispensing pipe is installed on the lower end face of the loading plate. Multiple sets of reaction chamber covers are provided at the lower part of the reagent dispensing pipe, and the number and position of the multiple sets of reaction chamber covers are the same as the multiple sets of reaction chamber test tubes. A reagent dispensing nozzle is installed below each set of reaction chamber covers. The loading plate is installed at the lower end of the reagent storage box. A reagent inlet is installed on the upper side wall of the reagent storage box, and one end of the reagent dispensing pipe is connected to the reagent storage box.

[0009] Preferably, a vertical telescopic cylinder is installed at the bottom of the guide hole, a limiting ring is installed at the upper part of the vertical telescopic cylinder, the upper part of the vertical telescopic cylinder is abutted against the lower part of the guide post, and a vertical spring is sleeved on the vertical telescopic cylinder, one end of the vertical spring is installed at the bottom of the limiting ring, and the other end of the vertical spring is installed on the bottom wall of the guide hole.

[0010] Preferably, the fixing assembly includes a fixing annular guide groove block, which is installed on the upper end face of the loading tray and is concentric with the loading tray. A first mounting groove is fixedly installed on the top wall of the protective cover. A first rotating rod is mounted on the inner walls of both ends of the first mounting groove. A fixed rod is rotatably mounted on the first rotating rod. A telescopic rod is mounted on the other end of the fixed rod near the side wall of the fixing annular guide groove block. A compression spring is sleeved on the telescopic rod, and a stop protrusion is mounted on the other end of the telescopic rod. A second mounting groove is mounted on the lower side wall of the fixed rod, and the inner walls of the second mounting groove are jointly mounted on... There is a second rotating rod, on which a connecting rod is rotatably mounted. A third rotating rod is rotatably mounted at the other end of the connecting rod. A third mounting groove is installed at both ends of the third rotating rod. A mounting block is installed at the bottom of the third mounting groove. A connecting cylinder is installed on the side wall of the mounting block near the inner wall of the base plate. A handle block is installed at the other end of the connecting cylinder. Limiting cylinders are installed on the side walls of the handle block near the outer wall of the base plate. A horizontal spring is sleeved on the connecting cylinder. A sliding groove is opened on the protective cover corresponding to the position of the connecting cylinder. Multiple sets of positioning holes are opened on the protective cover, with each set of positioning holes located on both sides of the sliding groove.

[0011] Preferably, one end of the compression spring is installed on the side wall of the telescopic rod, and the other end of the compression spring is installed on the side wall of the abutment protrusion, and the end of the abutment protrusion near the fixed ring guide groove is engaged with the fixed ring guide groove.

[0012] Preferably, one end of the horizontal spring is mounted on the side wall of the mounting block, and the other end of the horizontal spring is mounted on the inner wall of the base plate.

[0013] Preferably, the diameter of the connecting cylinder is the same as the width of the sliding groove, and the connecting cylinder and the sliding groove are perpendicular to each other.

[0014] The beneficial effects of this utility model are:

[0015] This invention employs a servo motor-driven automated stirring mechanism. A support platform rotates the samples and reagents within the reaction chamber test tubes in a regular pattern, ensuring sufficient contact between the samples and reagents in a short time. Simultaneously, the multi-chamber design supports batch testing, improving detection efficiency. In the reagent dispensing stage, the electromagnetic block connection mechanism, in conjunction with the multiple reaction chamber covers and nozzles, achieves precise reagent dispensing, avoiding waste and contamination. This ensures the accuracy and reliability of the amplification reaction from the source, significantly improving the quality of nucleic acid testing.

[0016] The equipment's fixing components provide a solid guarantee for stable operation. The fixed circular guide groove block and the abutment protrusion fit tightly together under the action of a compression spring, preventing the stirring component from shaking or shifting, thus ensuring the stability of the stirring effect. The design of the horizontal spring and sliding groove, along with the precise positioning of multiple sets of positioning holes, makes the installation and disassembly of the stirring component convenient and efficient, while ensuring accurate installation positioning. Furthermore, the equipment's integrated design is compact, occupies little space, and is easy to move and place, making it suitable for various testing environments. This rational structural design not only improves the stability and reliability of the equipment but also reduces operational difficulty and labor intensity, providing strong support for the efficient conduct of nucleic acid testing.

[0017] This invention improves detection efficiency, enabling batch testing to complete more testing tasks in a shorter time, significantly shortening the testing cycle and increasing work efficiency. A precise reagent dispensing mechanism reduces reagent waste and lowers testing costs. Simultaneously, the equipment's stability and reliability reduce duplicate testing caused by insufficient sample-reagent mixing, further saving reagent and labor costs. Attached Figure Description

[0018] To more clearly illustrate the technical solutions in this utility model or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only for this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0019] Figure 1 This is a first-view three-dimensional structural diagram of the present invention;

[0020] Figure 2 This is a two-dimensional structural diagram of the present invention from a second perspective;

[0021] Figure 3 This is a schematic diagram of the planar structure of some components of this utility model;

[0022] Figure 4 This is a schematic diagram of the enlarged planar structure of some of the fixing components of this utility model;

[0023] Figure 5 This is a cross-sectional enlarged planar structural diagram of the bearing platform of this utility model;

[0024] Figure 6 This utility model Figure 2 Enlarged structural diagram at point A in the middle.

[0025] The diagram is marked as follows:

[0026] 1. Base plate; 2. Support column; 3. Servo motor; 4. Protective cover; 5. U-shaped mounting bracket; 6. Sliding groove; 7. Positioning hole; 8. Guide hole; 9. Cylinder; 10. First electromagnetic block; 11. Second electromagnetic block; 12. Reagent storage box; 13. Reagent inlet; 14. Fixed ring guide groove block; 15. Loading tray; 16. Reagent dispensing pipe; 17. Reaction chamber cover; 18. Reagent dispensing nozzle; 19. Reaction chamber test tube; 20. Support plate; 21. Guide post; 22. Sealing ring; 23. Bearing platform; 24. First mounting groove; 25. First rotating rod; 26. Fixed rod; 27. Telescopic rod; 28. Compression spring; 29. ​​Abutting protrusion; 30. Second mounting groove; 31. Connecting rod; 32. Third mounting groove; 33. Mounting block; 34. Connecting cylinder; 35. Horizontal spring; 36. Handle block; 37. Limiting cylinder; 38. Vertical telescopic cylinder; 39. Vertical spring. Detailed Implementation

[0027] To make the objectives, technical solutions, and advantages of this utility model clearer, the present utility model will be further described in detail below with reference to specific embodiments.

[0028] It should be noted that, unless otherwise defined, the technical or scientific terms used in this utility model should have the ordinary meaning understood by one of ordinary skill in the art to which this utility model pertains. The terms "first," "second," and similar terms used in this utility model do not indicate any order, quantity, or importance, but are merely used to distinguish different components. Terms such as "comprising" or "including" mean that the element or object preceding the word encompasses the elements or objects listed following the word and their equivalents, without excluding other elements or objects. Terms such as "connected" or "linked" are not limited to physical or mechanical connections, but can include electrical connections, whether direct or indirect. Terms such as "upper," "lower," "left," and "right" are used only to indicate relative positional relationships; when the absolute position of the described object changes, the relative positional relationship may also change accordingly.

[0029] This utility model provides, for example Figures 1 to 6The nucleic acid amplification detection device with a multi-channel reagent dispensing structure shown includes: a base plate 1, four support columns 2 installed below the base plate 1, and a servo motor 3 fixedly installed between the four support columns 2; a protective cover 4 installed around the top of the base plate 1; a through-hole on the base plate 1 corresponding to the output end of the servo motor 3; a first control box installed at the bottom of the base plate 1, connected to the servo motor 3; a U-shaped mounting bracket 5 installed on the side wall of the base plate 1, with the other end of the U-shaped mounting bracket 5 located directly above the base plate 1; a cylinder 9 installed on the U-shaped mounting bracket 5 directly above the base plate 1; and a second control... The device comprises a cylinder 9 with a first electromagnetic block 10 mounted at its lower output end. A second electromagnetic block 11 is magnetically attached to the other end of the first electromagnetic block 10, and a reagent storage box 12 is fixedly mounted to the other end of the second electromagnetic block 11. A second control box is electrically connected to the second electromagnetic block 11. A stirring assembly is mounted directly above the base plate 1 to fuse the nucleic acid sample and reagents. A fixing assembly is located at the upper end of the protective cover 4 to fix the stirring assembly. This invention employs an automated stirring mechanism driven by a servo motor 3, which, through the support platform 23, drives the sample and reagents in the reaction chamber test tube 19 to rotate regularly, ensuring sufficient contact between the sample and reagents in a short time. Simultaneously, the multi-reaction chamber design supports batch testing, improving detection efficiency. In the reagent dispensing stage, the electromagnetic block connection mechanism, in conjunction with the multi-reaction chamber covers 17 and nozzles, achieves precise reagent dispensing, avoiding reagent waste and contamination, ensuring the accuracy and reliability of the amplification reaction from the source, and significantly improving the quality of nucleic acid detection. The fixing assembly provides a solid guarantee for the stable operation of the device. The fixed circular guide groove block 14 and the blocking protrusion 29 are tightly engaged under the action of the compression spring 28 to prevent the stirring assembly from shaking and displacing, ensuring the stability of the stirring effect. The design of the horizontal spring 35 and the sliding groove 6, as well as the precise positioning of multiple sets of positioning holes 7, makes the installation and disassembly of the stirring assembly convenient and efficient, while ensuring the accuracy of the installation position. In addition, the integrated design of the equipment is compact, occupies little space, is easy to move and place, and is suitable for different testing environments. This reasonable structural design not only improves the stability and reliability of the equipment, but also reduces the difficulty of operation and labor intensity, providing strong support for the efficient implementation of nucleic acid testing. By improving testing efficiency, the batch testing capability of this utility model enables more testing tasks to be completed in a short time, greatly shortening the testing cycle and improving work efficiency. The precise reagent dispensing mechanism reduces reagent waste and lowers testing costs. At the same time, the stability and reliability of the equipment reduce duplicate testing caused by uneven mixing of samples and reagents, further saving reagent and labor costs.

[0030] Furthermore, in this example, such as Figure 1 and Figure 3As shown, the stirring assembly includes a support platform 23, which is rotatably mounted on the upper surface of the base plate 1. The bottom of the support platform 23 is mounted on the output end of the servo motor 3. A support plate 20 is provided on the upper surface of the support platform 23. Four guide posts 21 are installed at the four corners of the lower surface of the support plate 20. Guide holes 8 are opened on the upper surface of the support platform 23 corresponding to the position of each guide post 21. The guide posts 21 are slidably inserted into the guide holes 8. Multiple sets of guide holes 8 are opened on the upper surface of the support platform 23. The grooves contain multiple sets of reaction chamber test tubes 19, each with a sealing ring 22 installed on the upper part of its inner wall. A circular hole with the same diameter as the outer wall of each reaction chamber test tube 19 is provided on the support plate 20 corresponding to the position of the test tube. A support ring is provided on the outer wall of the reaction chamber test tube 19 corresponding to the position on the support plate 20, with its bottom abutting against the upper surface of the support plate 20. A loading plate 15 is located directly above the support plate 20, and its lower surface is fitted with... There is a reagent delivery pipe 16, and multiple sets of reaction chamber covers 17 are provided at the lower part of the reagent delivery pipe 16. The number and position of the multiple sets of reaction chamber covers 17 are the same as the multiple sets of reaction chamber test tubes 19. A reagent delivery nozzle 18 is installed below each set of reaction chamber covers 17. The loading tray 15 is installed at the lower end of the reagent storage box 12. A reagent inlet 13 is installed on the upper side wall of the reagent storage box 12. One end of the reagent delivery pipe 16 is connected to the reagent storage box 12. A vertical telescopic cylinder 38 is installed at the bottom of the guide hole 8. A limiting ring is installed on the upper part of the vertical telescopic cylinder 38. The upper part of the vertical telescopic cylinder 38 abuts against the lower part of the guide column 21. A vertical spring 39 is sleeved on the vertical telescopic cylinder 38. One end of the vertical spring 39 is installed at the bottom of the limiting ring. The other end of the vertical spring 39 is installed on the bottom wall of the guide hole 8. The core function of the stirring assembly is to achieve full fusion of nucleic acid samples and reagents. Its working principle is based on the automated mechanical motion driven by the servo motor 3. When the device is started, the servo motor 3 begins to operate, driving the output of the servo motor 3 to rotate the carrier platform 23 in a regular manner under the control of the first control box. The carrier platform 23 has multiple sets of grooves, each containing a reaction chamber tube 19. These tubes are used to hold the nucleic acid samples and reagents to be tested. During the rotation of the carrier platform 23, the carrier plate 20 is connected to the carrier platform 23 via four guide pillars 21, which slide within the guide holes 8 of the carrier platform 23. Simultaneously, the vertical telescopic cylinder 38 and the vertical spring 39 allow the carrier plate 20 to move vertically to a certain extent. This vertical movement, combined with the rotation of the carrier platform 23, forms a composite motion in three-dimensional space. Under the action of the rotation of the carrier platform 23 and the vertical movement of the carrier plate 20, the nucleic acid samples and reagents in the reaction chamber tubes 19 continuously change position and state, thereby achieving thorough mixing.This mixing method is more uniform and efficient than traditional manual stirring, enabling the sample and reagents to come into full contact in a short time, providing a good foundation for subsequent amplification reactions. Furthermore, the design of multiple reaction chamber tubes 19 allows the device to simultaneously stir and test multiple samples, greatly improving the efficiency of batch testing. Each reaction chamber tube 19 is equipped with an independent sealing ring 22 and a support ring, ensuring the stability and sealing of the tube and preventing sample leakage and cross-contamination.

[0031] Furthermore, in this example, such as Figure 2 , Figure 4 and Figure 6As shown, the fixing assembly includes a fixing ring guide groove block 14, which is installed on the upper end face of the loading tray 15. The fixing ring guide groove block 14 and the loading tray 15 are concentric circles. A first mounting groove 24 is fixedly installed on the top wall of the protective cover 4. A first rotating rod 25 is installed on the inner walls of both ends of the first mounting groove 24. A fixing rod 26 is rotatably installed on the first rotating rod 25. A telescopic rod 27 is installed on the other end of the fixing rod 26 near the side wall of the fixing ring guide groove block 14. A mounting sleeve is installed on the telescopic rod 27. There is a compression spring 28, and a stop protrusion 29 is installed at the other end of the telescopic rod 27. A second mounting groove 30 is installed on the lower side wall of the fixed rod 26. A second rotating rod is installed on the inner wall of the second mounting groove 30. A connecting rod 31 is rotatably installed on the second rotating rod. A third rotating rod is rotatably installed at the other end of the connecting rod 31. A third mounting groove 32 is installed at both ends of the third rotating rod. A mounting block 33 is installed at the bottom of the third mounting groove 32. A connecting cylinder 3 is installed on the side wall of the mounting block 33 near the inner wall of the base plate 1. 4. A handle block 36 is installed at the other end of the connecting cylinder 34. Limiting cylinders 37 are respectively installed on the two side walls of the handle block 36 near the outer wall of the base plate 1. A horizontal spring 35 is sleeved on the connecting cylinder 34. A sliding groove 6 is opened on the protective cover 4 corresponding to the position of the connecting cylinder 34. Multiple sets of positioning holes 7 are opened on the protective cover 4. Each set of positioning holes 7 is located on both sides of the sliding groove 6. One end of the compression spring 28 is installed on the side wall of the telescopic rod 27, and the other end of the compression spring 28 is installed on the side wall of the abutment protrusion 29. One end of block 29, near the fixed ring guide groove block 14, engages with the fixed ring guide groove block 14. One end of the horizontal spring 35 is mounted on the side wall of the mounting block 33, and the other end is mounted on the inner wall of the base plate 1. The diameter of the connecting cylinder 34 is the same as the width of the sliding groove 6, and the connecting cylinder 34 and the sliding groove 6 are perpendicular to each other. The main function of the fixing component is to ensure that the stirring component remains stable during equipment operation, preventing it from shaking or shifting, thereby ensuring the stability and consistency of the stirring effect. Its working principle is mainly based on the elastic action of the compression spring 28 and the horizontal spring 35, as well as the mechanical cooperation between the components. When the stirring component is installed in place, the compression spring 28 is in a compressed state, and the abutment protrusion 29 is tightly attached to the fixed ring guide groove block 14 under the action of the compression spring 28, thereby limiting the large-scale movement of the loading plate 15 and the stirring component in the horizontal and vertical directions, ensuring the stability of the stirring component.When it is necessary to open the fixed assembly, pull the handle block 36. At this time, the mounting block 33 will compress the horizontal spring 35, and the limiting cylinder 37 will separate from the positioning hole 7. Then, you can pinch the handle block 36 and move it upward. As the handle block 36 moves upward, the mounting block 33 will push the connecting rod 31. The connecting rod 31 moves upward, causing the end of the fixed rod 26 with the abutment protrusion 29 to separate from the fixed ring guide groove block 14. At the same time, the compression spring 28 will return to its original position. When the handle block 36 moves upward to the position of the positioning hole 7 above the sliding groove 6, release the handle block 36. At this time, under the action of the horizontal spring 35, the limiting cylinder 37 will be locked into the positioning hole 7 above, thus completing the fixing of the fixed assembly after it has been released. The multiple sets of positioning holes 7 on the protective cover 4 are used to accurately position the connecting cylinder 34 to ensure that the installation position of the stirring assembly is accurate. This working principle, based on spring elasticity and mechanical cooperation, enables the fixing component to reliably secure the mixing component, while facilitating the installation and disassembly of the mixing component, thus improving the ease of operation and stability of the equipment.

[0032] Those skilled in the art should understand that the discussion of any of the above embodiments is merely exemplary and is not intended to imply that the scope of the present invention (including the claims) is limited to these examples; within the framework of the present invention, the technical features of the above embodiments or different embodiments can also be combined, the steps can be implemented in any order, and there are many other variations of the different aspects of the present invention as described above, which are not provided in the details for the sake of brevity.

[0033] This utility model is intended to cover all such substitutions, modifications, and variations that fall within the broad scope of the appended claims. Therefore, any omissions, modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this utility model should be included within the protection scope of this utility model.

Claims

1. A nucleic acid amplification and detection apparatus having a multi-channel reagent dispensing structure, characterized by, Include: The bottom plate (1), four support columns (2) are installed below the bottom plate (1), and a servo motor (3) is fixedly installed between the four support columns (2), a protective cover (4) is installed around the top of the bottom plate (1), and a through hole is formed on the bottom plate (1) corresponding to the position of the output end of the servo motor (3), and a first control box is installed at the bottom of the bottom plate (1), the first control box is connected with the servo motor (3), a stirring assembly is installed above the bottom plate (1), and the stirring assembly is used for fusing the nucleic acid sample to be detected and the reagent; the upper end of the protective cover (4) is provided with a fixing assembly, and the fixing assembly is used for fixing the stirring assembly.

2. The nucleic acid amplification and detection device with multi-channel reagent distribution structure according to claim 1, wherein, A U-shaped mounting bracket (5) is installed on the side wall of the bottom plate (1), the other end of the U-shaped mounting bracket (5) is located above the bottom plate (1), a gas cylinder (9) is installed on the position of the U-shaped mounting bracket (5) above the bottom plate (1), a second control box is installed on the side wall of the U-shaped mounting bracket (5), a first electromagnetic block (10) is installed on the lower output end of the gas cylinder (9), a second electromagnetic block (11) is magnetically attracted and installed on the other end of the first electromagnetic block (10), and a reagent storage box (12) is fixedly installed on the other end of the second electromagnetic block (11).

3. The nucleic acid amplification and detection device with multi-channel reagent distribution structure according to claim 2, wherein, The second control box is electrically connected with the second electromagnetic block (11).

4. The nucleic acid amplification and detection device with multi-channel reagent distribution structure according to claim 3, wherein, The stirring assembly comprises a bearing platform (23) which is snap-fitted and rotatably mounted on the upper end face of the bottom plate (1), and the bottom of the bearing platform (23) is mounted on the output end of the servo motor (3), the upper end face of the bearing platform (23) is provided with a bearing plate (20), the lower end face of the bearing plate (20) is provided with four guide columns (21) at the four corners, and the upper end face of the bearing platform (23) is provided with a guide hole (8) corresponding to the position of each guide column (21), the guide column (21) is slidingly inserted into the guide hole (8), and the upper end face of the bearing platform (23) is provided with a plurality of grooves, and a plurality of reaction cavity test tubes (19) are inserted into the grooves, a sealing ring (22) is mounted on the inner wall of the upper part of the reaction cavity test tube (19), and a circular hole with the same diameter as the outer wall of the reaction cavity test tube (19) is formed on the bearing plate (20) corresponding to the position of each reaction cavity test tube (19), and a bearing ring is arranged on the outer wall of the reaction cavity test tube (19) corresponding to the position of the bearing plate (20), the bottom of the bearing ring is abuttingly mounted on the upper end face of the bearing plate (20), a loading disc (15) is arranged above the bearing plate (20), a reagent feeding pipeline (16) is mounted on the lower end face of the loading disc (15), a plurality of reaction cavity covers (17) are arranged on the lower part of the reagent feeding pipeline (16), and the number and position of the plurality of reaction cavity covers (17) are the same as those of the plurality of reaction cavity test tubes (19), a reagent feeding nozzle (18) is mounted below each reaction cavity cover (17), and the loading disc (15) is mounted on the lower end of the reagent storage tank (12), a reagent feeding port (13) is mounted on the upper part of the side wall of the reagent storage tank (12), and one end of the reagent feeding pipeline (16) is connected with the reagent storage tank (12).

5. The nucleic acid amplification and detection apparatus having a multi-channel reagent distribution structure according to claim 4, wherein, The bottom of the guide hole (8) is provided with a vertical telescopic cylinder (38), the upper part of the vertical telescopic cylinder (38) is provided with a limiting ring, the upper part of the vertical telescopic cylinder (38) is abuttingly mounted on the lower part of the guide column (21), a vertical spring (39) is sleeved and mounted on the vertical telescopic cylinder (38), one end of the vertical spring (39) is mounted on the bottom of the limiting ring, and the other end of the vertical spring (39) is mounted on the bottom wall of the guide hole (8).

6. The nucleic acid amplification and detection device with multi-channel reagent distribution structure according to claim 5, wherein, The fixed assembly includes a fixed circular ring guide groove block (14), the fixed circular ring guide groove block (14) is installed on the upper end surface of the loading disc (15), and the fixed circular ring guide groove block (14) is concentric with the loading disc (15), and the top wall of the protective cover (4) is fixedly provided with a first mounting groove (24), the inner walls of both ends of the first mounting groove (24) are jointly provided with a first rotating rod (25), the first rotating rod (25) is rotatably provided with a fixed rod (26), one end of the fixed rod (26) is provided with an extension rod (27) close to the side wall of the fixed circular ring guide groove block (14), the extension rod (27) is provided with a compression spring (28), and the other end of the extension rod (27) is provided with a resisting block (29), and the lower side wall of the fixed rod (26) is provided with a second mounting groove (30), the inner walls of the second mounting groove (30) are jointly provided with a second rotating rod, the second rotating rod is rotatably provided with a connecting rod (31), the other end of the connecting rod (31) is rotatably provided with a third rotating rod, the both ends of the third rotating rod are provided with a third mounting groove (32), the bottom of the third mounting groove (32) is provided with a mounting circular block (33), the mounting circular block (33) is provided with a connecting cylinder (34) close to one end of the inner wall of the bottom plate (1), the other end of the connecting cylinder (34) is provided with a handle block (36), the handle block (36) is provided with a limiting cylinder (37) close to the both end side walls of the outer wall of the bottom plate (1), and the connecting cylinder (34) is provided with a horizontal spring (35), and the protective cover (4) is provided with a sliding groove (6) corresponding to the position of the connecting cylinder (34), and the protective cover (4) is provided with a plurality of positioning holes (7), each of the positioning holes (7) is located on the both sides of the sliding groove (6).

7. The nucleic acid amplification and detection device with multi-channel reagent distribution structure according to claim 6, wherein, One end of the compression spring (28) is installed on the side wall of the extension rod (27), the other end of the compression spring (28) is installed on the side wall of the resisting block (29), and one end of the resisting block (29) close to the fixed circular ring guide groove block (14) is matched with the fixed circular ring guide groove block (14).

8. The nucleic acid amplification and detection device with multi-channel reagent distribution structure according to claim 7, wherein, One end of the horizontal spring (35) is installed on the side wall of the mounting circular block (33), and the other end of the horizontal spring (35) is installed on the inner wall of the bottom plate (1).

9. The nucleic acid amplification and detection device with multi-channel reagent distribution structure according to claim 8, wherein, The diameter size of the connecting cylinder (34) is the same as the width size of the sliding groove (6), and the connecting cylinder (34) and the sliding groove (6) are in perpendicular relationship.