Small multichannel amplification detection device
By designing a small, multi-channel amplification detection device, and using a detection component composed of an LED light source and a photoelectric sensing module, we have achieved portable and low-cost parallel detection of multiple targets. This solves the problems of large size and complex operation of traditional equipment and meets the high-throughput requirements of primary healthcare and on-site monitoring.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-04-24
- Publication Date
- 2026-04-03
AI Technical Summary
Traditional nucleic acid amplification equipment is bulky, complex to operate, has limited throughput, and is expensive, making it difficult to meet the high-throughput and rapid screening needs of primary healthcare and on-site monitoring.
A small, multi-channel amplification detection device was designed. The detection component consists of an LED light source, a filter, a light guide, a focusing lens, and a photoelectric sensing module. It enables parallel detection of multiple targets and uses a control circuit to control multiple light sources to illuminate in turn, thereby achieving rapid data acquisition.
It enables portable, low-cost, and easy-to-operate parallel detection of multiple targets, meeting the needs of primary healthcare and on-site monitoring.
Smart Images
Figure CN224077402U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of testing equipment technology, specifically to a small multi-channel amplification testing device. Background Technology
[0002] With the rapid development of molecular diagnostic technology and the surge in demand for point-of-care testing (POCT), traditional nucleic acid amplification equipment (such as PCR instruments) is increasingly unable to meet the high-throughput, rapid screening needs of primary healthcare, on-site monitoring, and resource-constrained scenarios due to its large size, complex operation, limited throughput, and high cost. Through technological innovation and system integration, small, multi-channel amplification and detection devices are gradually becoming an important development direction in the field of molecular diagnostics.
[0003] Therefore, it is necessary to design a small, multi-channel amplification and detection device that is portable. Utility Model Content
[0004] In view of the above-mentioned technical problems existing in the prior art, this utility model provides a small multi-channel amplification detection device that achieves parallel detection of multiple targets while maintaining portability.
[0005] This utility model discloses a small multi-channel amplification detection device, including a first heat insulation plate, a second heat insulation plate, and a detection component. The first heat insulation plate is installed on the upper side of the second heat insulation plate, and a mounting groove matching the detection tube is provided in the middle of the first and second heat insulation plates. A plurality of mounting channels extending into the mounting groove are provided between the first and second heat insulation plates. LED light sources and filters are arranged at intervals in the mounting channels. The detection component is installed on the lower side of the mounting groove.
[0006] Preferably, the detection component includes a light guide, a focusing lens, and a photoelectric sensing module arranged sequentially at intervals.
[0007] Preferably, the light guide is installed on the lower side of the mounting groove;
[0008] A heating sleeve is provided on the outside of the light guide.
[0009] Preferably, a heating element and a temperature sensor are provided on one side of the heating tube sleeve.
[0010] Preferably, it also includes a control circuit, which is connected to the LED light source, the photoelectric sensing module, the heating element and the temperature sensor respectively.
[0011] Preferably, a third heat insulation plate and a buffer seat are sequentially provided on the lower side of the second heat insulation plate;
[0012] The photoelectric sensing module is mounted on the buffer seat.
[0013] Preferably, the first and second heat insulation boards are tightly connected to prevent light leakage through the installation channel.
[0014] Preferably, it also includes a housing and a cover hinged to the upper side of the housing;
[0015] The first heat insulation plate, the second heat insulation plate, and the detection component are installed inside the housing.
[0016] Preferably, four installation channels are provided between the first heat insulation plate and the second heat insulation plate;
[0017] The axes of two adjacent installation channels are perpendicular;
[0018] The excitation wavelength of the LED light source in one mounting channel is different from that in another mounting channel.
[0019] Compared with the prior art, the beneficial effects of this utility model are as follows: the excitation light from the LED light source enters the detection tube installed in the mounting groove through the filter. After the reaction liquid in the detection tube absorbs the excitation light, it detects the emitted light. The emitted light is detected by the detection component on the lower side of the mounting groove and converted into an electrical signal, thereby detecting the reaction liquid in the detection tube. It has the characteristics of small size, convenience, low cost and easy operation, and can meet the needs of primary medical care and on-site monitoring scenarios. Attached Figure Description
[0020] Figure 1 This is a cross-sectional view of the small multi-channel amplification and detection device of this utility model;
[0021] Figure 2 This is an exploded view of the detection component;
[0022] Figure 3 This is a schematic diagram of the LED light source installation.
[0023] Marked in the image:
[0024] 1. Housing, 11. Cover, 12. Detection tube, 2. First heat insulation plate, 22. Second heat insulation plate, 23. Mounting slot, 25. Mounting channel, 3. LED light source, 4. Filter, 5. Third heat insulation plate, 52. Buffer seat, 6. Heating tube sleeve, 67. Temperature sensor, 68. Heating element, 7. Detection component, 71. Light guide, 72. Focusing lens, 74. Photoelectric sensing module, 8. Control circuit. Detailed Implementation
[0025] To make the objectives, technical solutions, and advantages of the embodiments of this utility model clearer, the technical solutions of the embodiments of this utility model will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some, not all, of the embodiments of this utility model. Based on the embodiments of this utility model, all other embodiments obtained by those skilled in the art without creative effort are within the protection scope of this utility model.
[0026] The present invention will now be described in further detail with reference to the accompanying drawings:
[0027] A small, multi-channel amplification detection device, such as Figures 1-3 As shown, the device includes a first heat insulation plate 2, a second heat insulation plate 22, and a detection component 7. The first heat insulation plate 2 is installed on the upper side of the second heat insulation plate 22. A mounting groove 23 matching the detection tube 12 is provided in the middle of the first and second heat insulation plates 2 and 22. Multiple mounting channels 25 extending towards the mounting groove 23 are provided between the first and second heat insulation plates 2 and 22. LED light sources and filters 4 are spaced apart within the mounting channels 25. The detection component 7 is installed on the lower side of the mounting groove 23. The detection tube 12 is a transparent detection tube.
[0028] The excitation light from the LED light source enters the detection tube 12 installed in the mounting groove 23 through the filter 4. After the reaction liquid in the detection tube absorbs the excitation light, it emits light. The emitted light is detected by the detection component on the lower side of the mounting groove 23 and converted into an electrical signal, thereby detecting the reaction liquid in the detection tube, such as detecting fluorescence intensity. It features small size, convenience, low cost, and ease of operation, and can meet the needs of primary healthcare and on-site monitoring scenarios.
[0029] The reaction solution and fluorescence detection are existing technologies, and will not be described in detail here.
[0030] The detection component 7 includes a light guide 71, a focusing lens 72, and a photoelectric sensing module 74 arranged at intervals in sequence. The photoelectric sensing module 74 is used to convert light signals into electrical signals. The stronger the light intensity, the stronger the electrical signal.
[0031] The light guide 71 is installed on the lower side of the mounting groove 23; a heating sleeve 6 is provided on the outer side of the light guide 71. The heating sleeve 6 heats or keeps the detection tube 12 in the mounting groove 23 warm. More specifically, a heating element 68 and a temperature sensor 67 are provided on one side of the heating sleeve 6. The temperature sensor 67 can be glued to the outside of the heating sleeve 6 with heat-resistant insulating adhesive. The control circuit controls the voltage across the heating element 68 through the electrical signal fed back by the temperature sensor 67, thereby controlling the temperature of the heating sleeve 6.
[0032] This utility model also includes a control circuit 8, which is connected to the LED light source 3, the photoelectric sensing module 74, the heating element 68 and the temperature sensor 67 respectively. The control circuit can be equipped with a microprocessor, such as an ARM or STM32 microprocessor, for controlling the LED light source 3, the photoelectric sensing module 74, the heating element 68 and the temperature sensor 67, and receiving electrical signals fed back by the photoelectric sensing module 74 and the temperature sensor 67.
[0033] like Figure 1 and Figure 2 A third heat insulation plate 5 and a buffer seat 52 are sequentially arranged on the lower side of the second heat insulation plate 22; the photoelectric sensing module 74 is installed on the buffer seat 52. The first heat insulation plate, the second heat insulation plate 22 and the third heat insulation plate 5 can be fixed together by long screws, and the buffer seat 52 is fixed on the lower side of the third heat insulation plate 5.
[0034] Figure 1 The housing 1 and the cover 11 hinged to the upper side of the housing 1 are also shown; the first heat insulation plate 2, the second heat insulation plate 22 and the detection assembly 7 are installed inside the housing 1.
[0035] like Figure 3 Four mounting channels 25 are provided between the first heat insulation plate 2 and the second heat insulation plate 22. The axes of two adjacent mounting channels 25 are perpendicular; the excitation wavelength of the LED light source in one mounting channel 25 is different from the excitation wavelength of the LED light source in another mounting channel 25. The first heat insulation plate 2 and the second heat insulation plate 22 are tightly connected to prevent light leakage through the mounting channels 25.
[0036] In this invention, the excitation light emitted by the LED light source 3 is filtered by the filter 4, passes through the wall of the detection tube, and is absorbed by the reaction liquid inside the detection tube. The reaction liquid then excites and emits light. The wavelength of the emitted light is usually different from the wavelength of the excitation light; the specific wavelength of the excitation light is determined by the reaction liquid, which is existing technology and will not be described in detail here. The excitation light enters the detection component 7 from the bottom of the detection tube 12, passes through the light guide 71 and the focusing lens 72, and is irradiated onto the photoelectric sensing module 74. The photoelectric sensing module 74 converts the light signal into an electrical signal. By sequentially turning on the LED light sources, multiple detection channels can be detected. Specifically, the control circuit controls the four light sources to illuminate in turn, which can complete the data acquisition of the four fluorescence channels in a very short time. While maintaining portability, it achieves parallel detection and accurate analysis of multiple targets.
[0037] The above are merely preferred embodiments of this utility model and are not intended to limit the scope of this utility model. Various modifications and variations can be made to this utility model by those skilled in the art. Any modifications, equivalent substitutions, or improvements made within the spirit and principles of this utility model should be included within the protection scope of this utility model.
Claims
1. A compact multi-channel amplification detection device, characterized by, It comprises a first heat insulation plate (2), a second heat insulation plate (22) and a detection assembly (7), The first heat insulation plate (2) is installed on the upper side of the second heat insulation plate (22), and the middle parts of the first heat insulation plate (2) and the second heat insulation plate (22) are provided with mounting grooves (23) matched with the detection tube (12); A plurality of mounting channels (25) extending to the mounting grooves (23) are arranged between the first heat insulation plate (2) and the second heat insulation plate (22); The mounting channels (25) are provided with LED light sources and optical filters (4) at intervals; The detection assembly (7) is installed on the lower side of the mounting groove (23).
2. The compact multi-channel amplification and detection device of claim 1, wherein, The detection assembly (7) comprises a light guide (71), a focusing lens (72) and a photoelectric sensing module (74) arranged at intervals.
3. The compact multi-channel amplification and detection device of claim 2, wherein, The light guide (71) is installed on the lower side of the mounting groove (23); The outer side of the light guide (71) is provided with a heating pipe sleeve (6).
4. The compact multi-channel amplification and detection device of claim 3, wherein, One side of the heating pipe sleeve (6) is provided with a heating sheet (68) and a temperature sensor (67).
5. The compact multi-channel amplification and detection device of claim 4, wherein, It also comprises a control circuit (8) connected with the LED light source (3), the photoelectric sensing module (74), the heating sheet (68) and the temperature sensor (67) respectively.
6. The compact multi-channel amplification and detection device of claim 5, wherein, The lower side of the second heat insulation plate (22) is provided with a third heat insulation plate (5) and a buffer seat (52) in sequence; The photoelectric sensing module (74) is installed on the buffer seat (52).
7. The compact multi-channel amplification and detection device of claim 1, wherein, The first heat insulation plate (2) and the second heat insulation plate (22) are tightly connected and keep the mounting channels (25) from leaking light.
8. The compact multi-channel amplification and detection device of claim 1, wherein, It also comprises a casing (1) and a cover (11) hinged on the upper side of the casing (1); The first heat insulation plate (2), the second heat insulation plate (22) and the detection assembly (7) are installed in the casing (1).
9. The compact multi-channel amplification and detection device of claim 1, wherein, Four mounting channels (25) are arranged between the first heat insulation plate (2) and the second heat insulation plate (22); The axes of two adjacent mounting channels (25) are perpendicular; The excitation light wavelength of the LED light source in one mounting channel (25) is different from that of the LED light source in another mounting channel (25).