Lopinavir intermediate drying device
By designing a combination of a rotating motor and an impact unit, the problem of uneven drying of lopinavir intermediates was solved, achieving a more thorough drying effect.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-05-13
- Publication Date
- 2026-04-03
AI Technical Summary
Existing lopinavir intermediate dryers suffer from uneven heating due to drug accumulation, resulting in poor drying performance.
A drying device comprising a rotating motor, a rotating shaft, a storage unit, and an impact unit was designed. Through the cooperation of rotation and impact blocks, the lopinavir intermediate is uniformly distributed and fully dried.
Uniform drying of lopinavir intermediates was achieved, preventing uneven drying caused by accumulation and improving the drying effect.
Smart Images
Figure CN224080574U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of drying equipment technology, specifically a drying device for lopinavir intermediates. Background Technology
[0002] Lopinavir is a novel protease inhibitor for HIV that works primarily by blocking the cleavage of Gag-Pol protein, producing immature, non-infectious viral particles.
[0003] A dryer is a mechanical device that uses heat to vaporize and release the moisture (generally water or other volatile liquid components) in a material to obtain a solid material with a specified moisture content. It is a mechanical device that realizes the drying process of materials. In the process of producing lopinavir, a large amount of lopinavir intermediates are generated. In order to preserve lopinavir intermediates for a long time, they usually need to be dried using a dryer.
[0004] Existing lopinavir intermediate dryers suffer from uneven heating during the drying process due to drug accumulation, resulting in some drug intermediates failing to dry completely and thus leading to poor drying efficiency.
[0005] Therefore, it is necessary to propose a drying device that can thoroughly dry the lopinavir intermediate. Utility Model Content
[0006] The purpose of this invention is to provide a lopinavir intermediate drying device to at least partially solve the above-mentioned technical problems, so as to achieve more thorough drying of lopinavir.
[0007] To achieve the above objectives, this utility model provides the following technical solution: It includes a drying oven, a rotating motor disposed on the inner wall of the drying oven facing outwards, a rotating shaft extending outwards and inside the drying oven, a storage unit connected to the center of the rotating shaft, and an impact unit disposed on the lower inner surface of the drying oven and vertically arranged with the storage unit. The storage unit includes a main box whose outer wall center is connected to the rotating shaft, a secondary box inserted inside the main box, a sealing ring fixedly installed on the outer wall of the secondary box, and a puller fixedly installed at the bottom of the sealing ring.
[0008] The impact unit includes a positioning cylinder with a groove at the top. A slider is slidably installed inside the groove. The inner wall of the slider is fixedly connected to an impact block inside the positioning cylinder. A first magnet is fixedly installed at the bottom of the impact block. A second magnet is magnetically connected to the bottom of the first magnet and fixedly connected to the extension end of an electric cylinder located directly below the positioning cylinder. Several pressure springs are fixedly installed at the bottom of the impact block. A top rod is fixedly installed on the lower surface inside the positioning cylinder below the first magnet.
[0009] Furthermore, both the main packaging box and the auxiliary packaging box are hollow inside, the lower surface area of the main packaging box is larger than the lower surface area of the auxiliary packaging box, and the main packaging box does not contact the inner wall of the drying oven.
[0010] Furthermore, the upper surface area of the impact block is smaller than the upper surface area of the sub-packet.
[0011] Furthermore, the driving speed of the rotating motor and the electric cylinder is 1:2, that is, when the rotating motor drives the rotating shaft to rotate one revolution, the electric cylinder performs two linear retraction and extension movements.
[0012] Furthermore, the impact block and the sub-pack are located on the same vertical reference plane.
[0013] Furthermore, the pressure spring does not contact other structures, and several pressure springs are evenly arranged and installed at the bottom of the impact block.
[0014] Furthermore, the height of the push rod is higher than the minimum state when the electric cylinder is retracted, and there are four push rods installed in a circular arrangement. The four push rods only contact the bottom of the first magnet, and the top of the push rods is rounded.
[0015] Compared with the prior art, the beneficial effects of this utility model are as follows:
[0016] In use, the lopinavir intermediate is placed into a secondary packaging box, which is then placed into a primary packaging box to store the lopinavir intermediate. A drive motor rotates the primary packaging box via a rotating shaft. When the primary packaging box rotates to a parallel state, the impact block in the impact unit pops up and contacts the surface of the primary or secondary packaging box, causing an impact and vibration. This vibrates the lopinavir intermediate in the storage unit, dispersing the accumulated drug and ensuring that the drug in each area can fully contact and be dried. This ensures thorough drying of the lopinavir intermediate and prevents uneven drying caused by accumulation. Attached Figure Description
[0017] To more clearly illustrate the technical solutions of the embodiments of this utility model, the accompanying drawings used in the description of the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.
[0018] Figure 1 This is a schematic diagram showing the internal front view of the overall structure of this embodiment;
[0019] Figure 2 This is a schematic internal cross-sectional view of the overall structure in this embodiment;
[0020] Figure 3 This is an enlarged schematic diagram of the structure at point A in this embodiment;
[0021] Figure 4 This is a bottom-view diagram showing the internal structure of the overall structure in this embodiment.
[0022] The attached diagram lists the components represented by each number as follows:
[0023] 100. Drying oven; 110. Rotary motor; 111. Rotating shaft;
[0024] 200. Storage unit; 210. Main packaging box; 220. Sub-packet; 221. Sealing ring; 222. Pull-out block;
[0025] 300, Impact unit; 310, Positioning cylinder; 311, Slide groove; 3111, Slider; 320, Impact block; 321, First magnet; 322, Pressure spring; 330, Electric cylinder; 331, Second magnet; 340, Push rod. Detailed Implementation
[0026] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those skilled in the art without creative effort are within the protection scope of the present utility model.
[0027] Please see Figure 1-4 This utility model provides a technical solution: a lopinavir intermediate drying device, including a drying box 100, a rotating motor 110 disposed on the inner wall of the drying box 100 facing outward, a rotating shaft 111 extending outward and inside the drying box 100, a storage unit 200 connected to the center of the rotating shaft 111, and an impact unit 300 disposed on the lower surface inside the drying box 100 and vertically disposed with the storage unit 200.
[0028] The drying oven 100 uses conventional electric heating drying method for heating and drying, without any other special methods, which will not be described in detail here. The rotating shaft 111 driven by the rotating motor 110 can drive the storage unit 200 to rotate, while the internal structure of the impact unit 300 is a straight up and down movement.
[0029] See Figure 1 , Figure 2 and Figure 4 In a preferred embodiment, the storage unit 200 includes a main box 210 whose outer wall center is connected to the rotating shaft 111. A secondary box 220 is inserted inside the main box 210. A sealing ring 221 is fixedly installed on the outer wall of the secondary box 220. A pull block 222 is fixedly installed at the bottom of the sealing ring 221. When it is necessary to separate the secondary box 220 from the main box 210 to pour out the lopinavir intermediate, the pull block 222 can be used to easily pull the secondary box 220 out of the main box 210, and then the lopinavir intermediate can be poured out. Both the main box 210 and the secondary box 220 are hollow inside. The lower surface area of the main box 210 is larger than the lower surface area of the secondary box 220. The main box 210 does not contact the inner wall of the drying oven 100.
[0030] After the lopinavir intermediate is stored inside the main packaging box 210, the auxiliary packaging box 220 can be inserted into the main packaging box 210 to prevent the lopinavir intermediate inside the main packaging box 210 from falling out during rotation. The sealing ring 221 can greatly increase the friction between the auxiliary packaging box 220 and the main packaging box 210, preventing the main packaging box 210 from loosening and falling off, maintaining stable installation, and the main packaging box 210 will not contact or obstruct other structures when rotating, that is, it maintains uniform rotation.
[0031] See Figure 2 , Figure 3 In a further preferred embodiment, the impact unit 300 includes a positioning cylinder 310, the top of the positioning cylinder 310 is provided with a groove 311, a slider 3111 is slidably installed inside the groove 311, and the inner wall of the slider 3111 is fixedly connected to the impact block 320 disposed inside the positioning cylinder 310.
[0032] The design of the slide 311 ensures that the impact block 320 maintains a stable path when moving up and down with the slider 3111, preventing angular deviation and thus preventing structural intersections or contact, reducing the impact of mutual structural operation.
[0033] The impact block 320 and the sub-box 220 are on the same vertical reference plane, and the upper surface area of the impact block 320 is smaller than the upper surface area of the sub-box 220.
[0034] The impact block 320 will impact the surface of the sub-packet 220 or the main packet 210, and the impact will be at the center of the main packet 210 and the sub-packet 220. The impact force of the impact block 320 will not be too large, and will only cause vibration inside the storage unit 200 through impact, without causing the rotation motor 110 and the rotation shaft 111 to loosen or fall off.
[0035] See Figure 3 In a further preferred embodiment, a first magnet 321 is fixedly installed at the bottom of the impact block, and a second magnet 331 is magnetically connected to the bottom of the first magnet 321 and fixedly connected to the protruding end of the electric cylinder 330 located directly below the positioning cylinder 310.
[0036] By attracting the first magnet 321 and the second magnet 331, the impact block 320 can be retracted from the pop-up state. That is, the extended end of the electric cylinder 330 drives the second magnet 331 to extend towards the impact block 320, so that the second magnet 331 attracts the first magnet 321. The extended end of the electric cylinder 330 then retracts, pulling the impact block 320 into the positioning cylinder 310.
[0037] Several pressure springs 322 are fixedly installed at the bottom of the impact block 320. The pressure springs 322 do not contact other structures. Several pressure springs 322 are evenly arranged at the bottom of the impact block 320.
[0038] When the impact block 320 moves downward, several pressure springs 322 are compressed and stored to accumulate elastic potential energy. When it is necessary to release the impact block 320, the pressure springs 322 release the elastic potential energy, causing the impact block 320 to be ejected directly upward and collide with the main packaging box 210 or the auxiliary packaging box 220.
[0039] See Figure 2 , Figure 3 Further preferably, a push rod 340 is fixedly installed on the lower surface of the positioning cylinder 310 below the first magnet 321. The height of the push rod 340 is higher than the minimum state when the extension end of the electric cylinder 330 is retracted. There are four push rods 340 arranged in a circle. The four push rods 340 only contact the bottom of the first magnet 321. The top of the push rod 340 is rounded.
[0040] When the pressure spring 322 and the impact block 320 move downwards a sufficient distance and the pressure spring 322 accumulates sufficient elastic potential energy, it continues to move downwards. At this time, the first magnet 321 contacts the push rod 340, so that all parts of the bottom of the first magnet 321 are in contact with the push rod 340. The push rod 340 and the first magnet 321 generate an interaction force. At this time, the extended end of the electric cylinder 330 drives the second magnet 331 to continue to move downwards. That is, the push rod 340 restricts the first magnet 321 from continuing to move downwards. The first magnet 321 and the second magnet 331 separate, and the pressure spring 322 is released from the downward auxiliary pulling force. The pressure spring 322 directly releases its elastic potential energy, which pops the impact block 320 upwards.
[0041] The driving speed of the rotating motor 110 and the electric cylinder 330 is 1:2. That is, when the rotating motor 110 drives the rotating shaft 111 to rotate one revolution, the electric cylinder 330 performs two linear retraction and extension movements. When the rotating motor 110 rotates half a revolution, that is, when the main packaging box 210 is facing down, the extension end of the electric cylinder 330 moves downward. When the main packaging box 210 is parallel to the impact block 320, the impact block 320 bounces upward and impacts the main packaging box 210.
[0042] When the rotating motor 110 drives the storage unit 200 to continue rotating, the sub-box 220 is facing down, and the extended end of the electric cylinder 330 moves downward. When the sub-box 220 is parallel to the impact block 320, the impact block 320 bounces upward and impacts the sub-box 220.
[0043] In the description of this utility model, it should be understood that the terms "coaxial", "bottom", "one end", "top", "middle", "other end", "upper", "side", "top", "inner", "front", "center", "both ends", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the drawings. They are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model.
[0044] In this utility model, unless otherwise explicitly specified and limited, the terms "installation", "setting", "connection", "fixing", "screw connection", etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal connection of two components or the interaction between two components. Unless otherwise explicitly limited, those skilled in the art can understand the specific meaning of the above terms in this utility model according to the specific circumstances.
[0045] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.
Claims
1. A lopinavir intermediate drying device, comprising a drying box (100), a rotating motor (110) arranged on the outer wall of the inner wall of the drying box (100), and a rotating shaft (111) extending into the interior of the drying box (100), a storage unit (200) connected to the center of the rotating shaft (111), and an impact unit (300) arranged vertically on the lower surface of the drying box (100) and the storage unit (200), characterized in that: the storage unit (200) comprises a main box (210) connected to the rotating shaft (111) at the center of the outer wall, a secondary box (220) inserted into the main box (210), a sealing ring (221) fixedly installed on the outer wall of the secondary box (220), and a pull block (222) fixedly installed on the bottom of the sealing ring (221); the impact unit (300) comprises a positioning cylinder (310), a sliding groove (311) is formed in the top of the positioning cylinder (310), a sliding block (3111) is slidably installed in the sliding groove (311), the inner wall of the sliding block (3111) is fixedly connected with an impact block (320) arranged in the positioning cylinder (310), a first magnet (321) is fixedly installed on the bottom of the impact block, a second magnet (331) is fixedly connected with the extension end of an electric cylinder (330) arranged below the positioning cylinder (310), a plurality of pressure springs (322) are fixedly installed on the bottom of the impact block (320), and a top rod (340) is fixedly installed on the lower surface of the positioning cylinder (310).
2. A lopinavir intermediate drying apparatus as claimed in claim 1, wherein: The main box (210) and the secondary box (220) are both hollow, the lower surface area of the main box (210) is greater than that of the secondary box (220), and the main box (210) is not in contact with the inner wall of the drying box (100).
3. A lopinavir intermediate drying apparatus as claimed in claim 1, wherein: The upper surface area of the impact block (320) is smaller than that of the secondary box (220).
4. A lopinavir intermediate drying apparatus as claimed in claim 1, wherein: The driving speed of the rotating motor (110) and the electric cylinder (330) is 1:2, that is, when the rotating motor (110) drives the rotating shaft (111) to rotate one circle, the electric cylinder (330) performs two linear thread contraction and extension movements.
5. A lopinavir intermediate drying apparatus as claimed in claim 3, wherein: The impact block (320) and the secondary box (220) are in the same vertical reference plane.
6. A lopinavir intermediate drying apparatus as claimed in claim 1, wherein: The pressure springs (322) are not in contact with other structures, and the plurality of pressure springs (322) are evenly arranged on the bottom of the impact block (320).
7. A lopinavir intermediate drying apparatus as claimed in claim 1, wherein: The height of the top rod (340) is higher than the minimum state of the extension end contraction of the electric cylinder (330), the top rod (340) is circularly arranged, four top rods (340) are only in contact with the bottom of the first magnet (321), and the top of the top rod (340) is circularly arranged.