Heparin sodium precipitation separation device

Abstract

The utility model discloses a heparin sodium precipitation and separation device, which relates to the technical field of heparin sodium precipitation and separation, and comprises a separation cylinder, the inner wall of the separation cylinder is connected with a precipitation cylinder in a sliding manner, the outer side of the separation cylinder is provided with an extraction mechanism, the extraction mechanism comprises a limiting frame, and the outer surface of the limiting frame is fixedly connected with the outer surface of the separation cylinder. The inner wall of the limiting frame is slidably connected with a lifting plate. The extraction mechanism is arranged, a first servo motor of the extraction mechanism drives a screw rod to rotate, so that a lifting plate in threaded connection with the screw rod can move up and down, and a water pumping pipe of a water pump can flexibly adjust the extraction position according to the actual heights of precipitates and a solution, so that the precipitates are prevented from being taken out by mistake when the solution is extracted; and secondly, due to the design of the filter plate and the fixed plate in the filter box, the extracted solution can be effectively filtered, the solution is further ensured not to be mixed with precipitates, and the separation purity and effect are improved.

Description

Technical Field

[0001] This utility model relates to the field of heparin sodium precipitation and separation technology, specifically a heparin sodium precipitation and separation device. Background Technology

[0002] Heparin sodium precipitation separation is a separation technique commonly used in biochemical or medical experiments. It is mainly used to separate heparin sodium from solution through precipitation. Heparin sodium is an anticoagulant drug that is widely used in clinical practice to prevent thrombosis. In some experiments, when heparin sodium coexists with other substances, certain chemical or physical conditions are used to induce the heparin sodium to precipitate and separate it from other components.

[0003] According to the utility model patent application CN212594159U, a heparin sodium precipitation separation device is disclosed, including a precipitation separation device body. Four column rods are arranged around the lower end face of the precipitation separation device body. One end of each column rod is fixedly connected to the lower end face of the precipitation separation device body. An observation port is provided on the front end face of the precipitation separation device body and is fixedly connected to the precipitation separation device body. A slag discharge port is provided on the lower end face of the precipitation separation device body.

[0004] While this device uses a sponge layer to adsorb precipitate, reducing the likelihood of precipitate floating due to internal liquid changes and preventing further contamination of the separated liquid, it suffers from several drawbacks. The fixed-height discharge pipe leads to variations in the volume of precipitate and solution after each separation, causing some precipitate to be carried away with the solution, resulting in material waste and limited practicality. Therefore, we provide a heparin sodium precipitation separation device to address these issues. Utility Model Content

[0005] The purpose of this invention is to overcome the shortcomings of the existing technology and provide a heparin sodium precipitation and separation device.

[0006] To achieve the above objectives, this utility model provides the following technical solution: a heparin sodium precipitation separation device, comprising a separation cylinder, a precipitation cylinder slidably connected to the inner wall of the separation cylinder, and an extraction mechanism provided on the outer side of the separation cylinder. The extraction mechanism includes a limiting frame, the outer surface of which is fixedly connected to the outer surface of the separation cylinder. A lifting plate is slidably connected to the inner wall of the limiting frame, and a water pump is fixedly connected to the upper surface of the lifting plate. The power input end of the water pump is fixedly connected to a water pumping pipe, and the outer surface of the water pumping pipe is connected to the inner wall of the lifting plate. The system is fixedly connected, with the outer surface of the pumping pipe slidably connected to the inner wall of the separation cylinder. A first servo motor is fixedly connected to the inner bottom wall of the limiting frame, and a screw is fixedly connected to the output end of the first servo motor. The top end of the screw is rotatably connected to the inner wall of the limiting frame, and the outer surface of the screw is threadedly connected to the inner wall of the lifting plate. A filter box is provided on the outer side of the separation cylinder, and a filter plate is slidably connected to the inner wall of the filter box. A fixing plate is fixedly connected to the upper surface of the filter plate, and the outer surface of the fixing plate is slidably connected to the inner wall of the filter box.

[0007] Furthermore, four support legs are fixedly connected to the outer surface of the separation cylinder, and a base is fixedly connected to the bottom surface of each support leg.

[0008] Furthermore, the inner wall of the sedimentation cylinder is threaded with four bolts, and the top of each bolt is threaded to the inner wall of the separation cylinder.

[0009] Furthermore, a cover plate is slidably connected to the inner wall of the separation cylinder, and a pull block is fixedly connected to the upper surface of the cover plate.

[0010] Furthermore, a second servo motor is fixedly connected to the upper surface of the separation cylinder, and the output end of the second servo motor passes through the separation cylinder and is fixedly installed with a stirring shaft.

[0011] Furthermore, a sealing ring is fixedly connected to the outer surface of the sedimentation cylinder, and the outer surface of the sealing ring is in contact with the inner wall of the separation cylinder.

[0012] Furthermore, the front and back of the filter box are fixedly connected to connecting frames, and the outer surface of the connecting frames is fixedly connected to the outer surface of the separation cylinder.

[0013] Compared with existing technologies, this heparin sodium precipitation and separation device has the following advantages:

[0014] This invention features an extraction mechanism. A first servo motor in the extraction mechanism drives a screw to rotate, allowing a lifting plate threaded to the screw to move up and down. This enables the water pump's extraction pipe to flexibly adjust its extraction position according to the actual height of the sediment and solution, thus preventing the accidental removal of sediment during solution extraction and significantly reducing waste. Furthermore, the design of the filter plate and fixing plate in the filter box effectively filters the extracted solution, further ensuring that no sediment is mixed in, improving the purity and effectiveness of the separation. The overall device structurally and functionally solves the problems of traditional equipment that easily wastes sediment and lacks practicality when extracting the separated solution. Attached Figure Description

[0015] Figure 1 This is a three-dimensional structural diagram of the separation cylinder of this utility model.

[0016] Figure 2 This is a three-dimensional structural diagram of the sedimentation cylinder of this utility model.

[0017] Figure 3 This is a cross-sectional three-dimensional structural schematic diagram of the separation cylinder of this utility model.

[0018] Figure 4 This is a cross-sectional three-dimensional structural schematic diagram of the limiting frame of this utility model.

[0019] In the diagram: 1. Separation cylinder; 2. Sedimentation cylinder; 3. Extraction mechanism; 301. Limiting frame; 302. Lifting plate; 303. Water pump; 304. Water pipe; 305. Filter box; 306. Filter plate; 307. Fixing plate; 308. First servo motor; 309. Screw; 310. Support leg; 311. Base; 312. Connecting frame; 313. Second servo motor; 314. Pull block; 315. Bolt; 316. Cover plate; 317. Sealing ring; 318. Stirring shaft. Detailed Implementation

[0020] The principles and features of this utility model are described below with reference to the accompanying drawings. The examples given are only for explaining this utility model and are not intended to limit the scope of this utility model.

[0021] This embodiment provides a heparin sodium precipitation separation device, which can prevent waste of precipitate material when exporting the separated solution.

[0022] Reference Figure 1 , Figure 2 , Figure 3 and Figure 4A heparin sodium precipitation separation device includes a separation cylinder 1, a precipitation cylinder 2 slidably connected to the inner wall of the separation cylinder 1, and an extraction mechanism 3 provided on the outer side of the separation cylinder 1. The extraction mechanism 3 includes a limiting frame 301. Four support legs 310 are fixedly connected to the outer surface of the separation cylinder 1, and a base 311 is fixedly connected to the bottom surface of each support leg 310. The support legs 310 provide vertical support for the separation cylinder 1, enabling the entire heparin sodium precipitation separation device to be stably placed on the working plane. The distribution of the four support legs 310 can make the support more uniform, and the base 311 increases the contact area with the support plane, thereby improving the stability of the entire device.

[0023] Reference Figure 1 , Figure 2 , Figure 3 and Figure 4 The outer surface of the limiting frame 301 is fixedly connected to the outer surface of the separation cylinder 1. The inner wall of the limiting frame 301 is slidably connected to the lifting plate 302. The upper surface of the lifting plate 302 is fixedly connected to the water pump 303. The inner wall of the sedimentation cylinder 2 is threadedly connected to four bolts 315. The top of each bolt 315 is threadedly connected to the inner wall of the separation cylinder 1. This threaded connection method can ensure a tight connection between the sedimentation cylinder 2 and the separation cylinder 1. During the precipitation and separation process of heparin sodium, different pressures and vibrations may be involved. The connection of the four bolts 315 can withstand these external forces, prevent the sedimentation cylinder 2 from loosening or shifting in the separation cylinder 1, and ensure that the precipitation and separation process is carried out in a relatively stable space.

[0024] Reference Figure 1 , Figure 2 , Figure 3 and Figure 4 The power input end of the water pump 303 is fixedly connected to the water pump pipe 304. The outer surface of the water pump pipe 304 is fixedly connected to the inner wall of the lifting plate 302. The outer surface of the water pump pipe 304 is slidably connected to the inner wall of the separation cylinder 1. The inner wall of the separation cylinder 1 is slidably connected to the cover plate 316. The upper surface of the cover plate 316 is fixedly connected to the pull block 314. The cover plate 316 can be easily opened and closed. The pull block 314 provides an easy point for the operator to apply force. When adding heparin sodium solution or other operating substances into the separation cylinder 1, the cover plate 316 can be easily opened by pulling the pull block 314. After the operation is completed, the cover plate 316 can be easily closed to ensure that the internal environment of the separation cylinder 1 is relatively closed and to prevent external impurities from entering and affecting the sedimentation and separation effect.

[0025] Reference Figure 1 , Figure 2 , Figure 3 and Figure 4A first servo motor 308 is fixedly connected to the inner bottom wall of the limiting frame 301. A screw 309 is fixedly connected to the output end of the first servo motor 308. The top end of the screw 309 is rotatably connected to the inner wall of the limiting frame 301. A second servo motor 313 is fixedly connected to the upper surface of the separation cylinder 1. The output end of the second servo motor 313 passes through the separation cylinder 1 and is fixedly installed with a stirring shaft 318. The second servo motor 313 drives the stirring shaft 318 to rotate, which can stir the heparin sodium solution in the separation cylinder 1. Before precipitation separation, thorough stirring can make the various components in the heparin sodium solution more uniformly mixed, ensuring that the precipitation reaction takes place in a uniform environment, which is beneficial to improving the precipitation effect and quality.

[0026] Reference Figure 1 , Figure 2 , Figure 3 and Figure 4 The outer surface of the screw 309 is threadedly connected to the inner wall of the lifting plate 302. A filter box 305 is provided on the outer side of the separation cylinder 1. A filter plate 306 is slidably connected to the inner wall of the filter box 305. A sealing ring 317 is fixedly connected to the outer surface of the sedimentation cylinder 2. The outer surface of the sealing ring 317 is in contact with the inner wall of the separation cylinder 1. The sealing ring 317 plays a sealing role to prevent the heparin sodium solution or precipitate from leaking from the gap between the sedimentation cylinder 2 and the separation cylinder 1 during the sedimentation separation process. This sealing is very important for ensuring the stability of the sedimentation environment in the sedimentation cylinder 2. It also prevents the solution from leaking to other parts of the device, affecting the normal operation of other components or causing waste of solution.

[0027] Reference Figure 1 , Figure 2 and Figure 3 A fixing plate 307 is fixedly connected to the upper surface of the filter plate 306. The outer surface of the fixing plate 307 is slidably connected to the inner wall of the filter box 305. A connecting frame 312 is fixedly connected to both the front and back of the filter box 305. The outer surface of the connecting frame 312 is fixedly connected to the outer surface of the separation cylinder 1. The connecting frame 312 connects the filter box 305 and the separation cylinder 1 into an integral structure, making the entire heparin sodium precipitation separation device more compact in structure. This integrity helps the various components work together during the operation of the device, reducing the risk of failure caused by the relative displacement between components.

[0028] Working principle: In use, the operator first connects the power supply of the first servo motor 308, the second servo motor 313, and the water pump 303 to an external power source to ensure stable power supply. The separation cylinder 1 contains a sedimentation cylinder 2, which is connected and fixed to the separation cylinder 1 by four bolts 315. Then, the separation cylinder 1 is opened through the cover plate 316, allowing the material to be introduced into its interior. The second servo motor 313 on the separation cylinder 1 then starts, and its output stirring shaft 318 begins to rotate, which helps to agitate the material inside the cylinder. The mixture is stirred to facilitate the precipitation of heparin sodium. After precipitation and separation, the first servo motor 308 within the limiting frame 301 is activated. The first servo motor 308 drives the screw 309 to rotate. The screw 309 is threadedly connected to the lifting plate 302, allowing the lifting plate 302 to slide up and down within the limiting frame 301. The lifting plate 302 includes vertically oriented blocks. The water pump 303 on the lifting plate 302 adjusts its position as the lifting plate 302 moves. The water pump pipe 304 of the water pump 303 is located inside the separation cylinder 1. After sliding and adjusting to a suitable height, start the water pump 303 to extract the liquid from the separation cylinder 1. The extracted liquid enters the filter box 305 through the pump's outlet. The filter box 305 contains a filter plate 306, which is fixed inside the filter box 305 by a fixing plate 307. This further filters the extracted liquid, preventing waste due to residual sediment in the solution. Simultaneously, the outlet on one side of the filter box 305 allows the filtered solution to be discharged. After the separation is complete, the operator removes the fixing plate 307 and the filter plate 306. 6. Pull out the filter residue on the surface and unscrew bolt 315 to separate the sedimentation cylinder 2 from the separation cylinder 1. Since the separation device is small to medium-sized and all the solution inside the separation cylinder 1 has been discharged, only sedimentation cylinder 2 contains some sediment. Therefore, sedimentation cylinder 2 is relatively light and can be lifted out by the staff. Then, the sediment inside sedimentation cylinder 2 can be removed. The staff can also use an auxiliary tool, a crane trolley, to pull out sedimentation cylinder 2. This separation method makes it convenient for the staff to remove the sediment at the bottom.

[0029] The above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. A heparin sodium precipitation separation device, comprising a separation cylinder (1), characterized in that: A sedimentation cylinder (2) is slidably connected to the inner wall of the separation cylinder (1). An extraction mechanism (3) is provided on the outer side of the separation cylinder (1). The extraction mechanism (3) includes a limiting frame (301). The outer surface of the limiting frame (301) is fixedly connected to the outer surface of the separation cylinder (1). A lifting plate (302) is slidably connected to the inner wall of the limiting frame (301). A water pump (303) is fixedly connected to the upper surface of the lifting plate (302). A water pump (304) is fixedly connected to the power input end of the water pump (303). The outer surface of the water pump (304) is fixedly connected to the inner wall of the lifting plate (302). The outer surface of the water pump (304) is also fixedly connected to the inner wall of the separation cylinder (1). The sliding connection is provided. The inner bottom wall of the limiting frame (301) is fixedly connected to a first servo motor (308). The output end of the first servo motor (308) is fixedly connected to a screw (309). The top end of the screw (309) is rotatably connected to the inner wall of the limiting frame (301). The outer surface of the screw (309) is threadedly connected to the inner wall of the lifting plate (302). A filter box (305) is provided on the outer side of the separating cylinder (1). A filter plate (306) is slidably connected to the inner wall of the filter box (305). A fixing plate (307) is fixedly connected to the upper surface of the filter plate (306). The outer surface of the fixing plate (307) is slidably connected to the inner wall of the filter box (305).

2. The heparin sodium precipitation separation device according to claim 1, characterized in that: The outer surface of the separation cylinder (1) is fixedly connected with four support legs (310), and the bottom surface of each support leg (310) is fixedly connected with a base (311).

3. The heparin sodium precipitation separation device according to claim 1, characterized in that: The inner wall of the sedimentation cylinder (2) is threaded with four bolts (315), and the top of each bolt (315) is threaded to the inner wall of the separation cylinder (1).

4. The heparin sodium precipitation separation device according to claim 1, characterized in that: The inner wall of the separation cylinder (1) is slidably connected to a cover plate (316), and a pull block (314) is fixedly connected to the upper surface of the cover plate (316).

5. The heparin sodium precipitation separation device according to claim 1, characterized in that: The upper surface of the separation cylinder (1) is fixedly connected to a second servo motor (313), and the output end of the power of the second servo motor (313) passes through the separation cylinder (1) and is fixedly installed with a stirring shaft (318).

6. The heparin sodium precipitation separation device according to claim 1, characterized in that: A sealing ring (317) is fixedly connected to the outer surface of the sedimentation cylinder (2), and the outer surface of the sealing ring (317) is in contact with the inner wall of the separation cylinder (1).

7. The heparin sodium precipitation separation device according to claim 1, characterized in that: The filter box (305) is fixedly connected to the front and back of the filter box (305), and the outer surface of the filter box (312) is fixedly connected to the outer surface of the separator (1).

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