Frame body for microdialysis pre-test medicine bottles

By designing a frame for microdialysis pre-test vials, the inconvenience of water bath heating of compounds and probe activation in microdialysis pre-test experiments was solved, achieving stable fixation of vials and probes and ensuring smooth experiment execution.

CN224086793UActive Publication Date: 2026-04-07WUXI APPTEC (SHANGHAI) CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-04-18
Publication Date
2026-04-07

AI Technical Summary

Technical Problem

The lack of a dedicated device in the existing technology for microdialysis pre-test experiments makes compound water bath heating and probe activation operations inconvenient and prone to probe damage.

Method used

A frame for microdialysis pre-test vials was designed, including a vertical plate, multiple partitions and fasteners. The vials and probes are fixed by limiting holes and fasteners, providing stable placement and fixation, and is suitable for water bath operation.

Benefits of technology

This design allows for convenient placement of the vial and stable probe placement, preventing damage caused by improper operation and ensuring the smooth conduct of the microdialysis pre-test experiment.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a frame body for microdialysis pre-test medicine bottles, which comprises vertical plates on two sides of the frame body, and a first-layer partition plate, a second-layer partition plate, a movable partition plate and a third-layer partition plate which are arranged between the vertical plates, the first-layer partition plate is close to the top of the frame body and is provided with a first limiting hole, and the second-layer partition plate is close to the top of the frame body and is provided with a second limiting hole. The second-layer partition plate is positioned in the middle of the rack body and is provided with a second limiting hole corresponding to the first limiting hole; the movable partition plate is detachably arranged at the position, close to the bottom face of the second-layer partition plate, of the rack body, the third-layer partition plate is arranged at the bottom of the rack body, and a fixing piece is arranged at the position, close to the first limiting hole, of the first-layer partition plate. According to the frame body for the microdialysis pre-test medicine bottle, during microdialysis pre-test, the medicine bottle can be conveniently placed, water bath operation and activation of an experimental probe are facilitated, the medicine bottle can be well fixed and prevented from shaking, operation is convenient, the microdialysis pre-test experiment can be smoothly carried out, and the service life of the microdialysis pre-test medicine bottle is prolonged. And unnecessary loss caused by misoperation is effectively avoided.
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Description

Technical Field

[0001] This utility model relates to the field of animal experimental equipment technology, and in particular to a frame for a microdialysis pre-test drug bottle. Background Technology

[0002] Before formally conducting animal microdialysis experiments (such as mouse and rat microdialysis experiments), a preliminary test is required. This test simulates the in vivo environment of animals to determine the recovery rate of different compounds and identify the optimal conditions for the experiment. During the preliminary test, glass bottles or centrifuge tubes containing probes and compound reagents need to be placed in a water bath for preheating or activation.

[0003] However, in the current technology, there is no device specifically for pre-test experiments, which makes it very inconvenient to heat compounds in a water bath or activate probes. Improper operation can damage the probes and render them unusable. Utility Model Content

[0004] The technical problem to be solved by this utility model is to provide a holder for microdialysis pre-test vials, which can facilitate the placement of vials and fix vials, probes, etc. during microdialysis pre-testing, thus facilitating the smooth conduct of the pre-test.

[0005] To solve the above-mentioned technical problems, the present invention provides a microdialysis pre-test vial holder, comprising:

[0006] Uprights, located on both sides of the frame;

[0007] The first partition is located near the top of the frame, and the first partition has a first limiting hole.

[0008] The second partition is located in the middle of the frame, and the second partition has a second limiting hole at the position corresponding to the first limiting hole;

[0009] A movable partition is detachably installed on the bottom surface of the frame near the second layer partition;

[0010] The third partition is located near the bottom of the frame;

[0011] A fastener is disposed on the first layer partition and near the first limiting hole.

[0012] Preferably, the fastener includes a fixing part and an adhesive part, the adhesive part being bent and bonded to the fixing part, and the fixing part being connected to the first layer partition.

[0013] Preferably, the fasteners are distributed on both sides of the first limiting hole in the width direction of the frame.

[0014] Preferably, the number of the first limiting holes is at least one;

[0015] The number of the second limiting holes is at least one, and the number is the same as the number of the first limiting holes.

[0016] Preferably, the number of the first limiting holes is 2-10, and the first limiting holes are distributed along the length direction of the frame.

[0017] Preferably, the movable partition is mounted on the upright plate via a slide rail.

[0018] Ideally, the frame is also equipped with handles.

[0019] Preferably, the handle includes a connecting rod and a pull ring, the pull ring being formed at the top of the connecting rod, the connecting rod being fixedly installed at the center of the second partition and extending toward the first partition to penetrate and exceed the first partition.

[0020] Preferably, the handle is made of heat-insulating material.

[0021] This invention provides a holder for microdialysis pre-test vials, which facilitates the placement of vials, water bath operation, and activation of experimental probes during microdialysis pre-tests. It also provides excellent fixation for the vials, preventing shaking, and is easy to operate, ensuring the smooth progress of microdialysis pre-test experiments and effectively avoiding unnecessary losses due to improper operation. Attached Figure Description

[0022] To more clearly illustrate the technical solution of this utility model, the drawings used in this utility model will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained from these drawings without creative effort.

[0023] Figure 1 This is a schematic diagram of an embodiment of the microdialysis pre-test vial holder of this utility model;

[0024] Figure 2 This is a schematic diagram of a fixing component of an embodiment of the microdialysis pre-test vial frame of this utility model, showing the fixing component in its unfolded state.

[0025] Figure 3 This is a schematic diagram of a fastener of a microdialysis pre-test vial holder according to an embodiment of the present invention, showing the bent state of the adhesive portion of the fastener;

[0026] Figure 4 This is a top view of an embodiment of the microdialysis pre-test vial holder of this utility model, showing the fixing member fixing the probe;

[0027] Figure 5 This is a schematic diagram of an embodiment of the microdialysis pre-test drug bottle holder of this utility model, wherein the handle is provided on the upright plate;

[0028] In the diagram, 1-upright plate; 2-first layer partition; 21-first limiting hole; 3-second layer partition; 31-second limiting hole; 4-movable partition; 5-third layer partition; 6-fixing component; 61-fixing part; 62-adhesive part; 7-handle; 71-connecting rod; 72-pull ring; 8-probe. Detailed Implementation

[0029] The technical solutions of this utility model will now be clearly and completely described with reference to the accompanying drawings. Obviously, the described embodiments are only some, not all, of the embodiments of this utility model. All other embodiments obtained by those skilled in the art based on the embodiments of this utility model without creative effort are within the scope of protection of this utility model.

[0030] refer to Figure 1 This invention discloses a microdialysis pre-test vial holder, comprising:

[0031] Uprights, located on both sides of the frame;

[0032] The first partition is located near the top of the frame, and the first partition has a first limiting hole.

[0033] The second partition is located in the middle of the frame, and the second partition has a second limiting hole at the position corresponding to the first limiting hole;

[0034] A movable partition is detachably installed on the bottom surface of the frame near the second layer partition;

[0035] The third partition is located near the bottom of the frame;

[0036] A fastener is disposed on the first layer partition and near the first limiting hole.

[0037] In this embodiment of the invention, the uprights on both sides of the frame mainly serve to support the main body. A first layer of partition, a second layer of partition, and a third layer of partition are fixedly installed between the uprights on both sides. The uprights on both sides, along with the first, second, and third layers of partition, form the overall frame structure of the frame. The first limiting hole and the corresponding second limiting hole are used to limit and fix the medicine bottles (glass bottles, centrifuge tubes, etc.). The size of the hole diameter can be determined according to the size of the medicine bottle, and the inner side of the hole can be improved by adding a buffer pad to better fix and limit the medicine bottle. During the microdialysis pre-test, when the frame is used to place glass bottles in a water bath, a movable partition is installed. After the glass bottle passes through the first and second limiting holes, its bottom is located on the movable partition. When the frame is used for the preliminary preparation of microdialysis experimental probe activation, the movable partition is removed. After the centrifuge tube passes through the first and second limiting holes, its bottom is placed on the third layer of partition, and the probe is fixed with a fixing component. It should be noted that the second limiting hole corresponds to the first limiting hole in the vertical direction. When the medicine bottle is placed vertically, it can pass through both the first and second limiting holes at the same time.

[0038] The microdialysis pre-test vial holder provided by this utility model is designed for microdialysis pre-testing. It facilitates the placement of vials, water bath operation, and activation of experimental probes. It also provides excellent fixation for the vials, preventing shaking, and is easy to operate, thus ensuring the smooth progress of microdialysis pre-testing experiments and effectively avoiding unnecessary losses due to improper operation.

[0039] In one specific implementation, reference is made to... Figure 2 and Figure 3 The fastener includes a fixing part and an adhesive part. The adhesive part is bent and bonded to the fixing part, and the fixing part is connected to the first layer partition. Preferably, the fastener is distributed on both sides of the first limiting hole in the width direction of the frame. In this specific embodiment, the fastener can be, for example, a Velcro strap. After the probe is placed at the fixing part, the adhesive part is bent and bonded to the fixing part, thereby fastening (clamping) the probe between the fixing part and the adhesive part, thus fixing the probe (see reference). Figure 4 Preferably, the adhesive part is formed on one side of the fixing part and extends along the length of the frame. The fixing part is fixedly connected to the first partition by adhesive.

[0040] In one specific embodiment, the number of first limiting holes is at least one; the number of second limiting holes is at least one, and the same as the number of first limiting holes. Preferably, the number of first limiting holes is 2-10, and the first limiting holes are distributed along the length direction of the frame. Understandably, the number of first and second limiting holes is related to the number of medicine bottles. Generally, 2-10 first limiting holes and corresponding second limiting holes can meet the experimental requirements. When there are multiple first limiting holes and corresponding second limiting holes, they can also be arranged in multiple rows, with each row arranged along the length direction of the frame.

[0041] In one specific embodiment, the movable partition is mounted to the upright plate via a slide rail. Understandably, the movable partition can both slide and be disassembled; therefore, it is preferable to mount it to the upright plate of the frame via a slide rail. The slide rail has no limiting blocks at its ends, and when the movable partition slides to the end of the slide rail, it disengages from the slide rail, enabling the disassembly operation.

[0042] In one specific embodiment, the frame is also equipped with a handle. Preferably, the handle includes a connecting rod and a pull ring, the pull ring being formed at the top of the connecting rod, the connecting rod being fixedly installed at the center of the second partition and extending towards the first partition to penetrate and exceed the first partition. More preferably, the handle is made of heat-insulating material. Understandably, the handle facilitates the operator's access to and from the frame, and the connecting rod is installed to the second partition, for example, via a threaded connection. The shape and installation method of the handle are not intended to be constrained by this; see reference [reference needed]. Figure 5 The handle can also be installed on the top surface of the upright plate by hinge, or any handle in the prior art is applicable to this utility model.

[0043] The above description is only a preferred embodiment of the present utility model and is not intended to limit the scope of protection of the present utility model. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the scope of protection of the present utility model.

Claims

1. A frame for a microdialysis pre-test vial, characterized in that, include: Uprights, located on both sides of the frame; The first partition is located near the top of the frame, and the first partition has a first limiting hole. The second partition is located in the middle of the frame, and the second partition has a second limiting hole at the position corresponding to the first limiting hole; A movable partition is detachably installed on the bottom surface of the frame near the second layer partition; The third partition is located near the bottom of the frame; A fastener is disposed on the first layer partition and near the first limiting hole.

2. The microdialysis pre-test vial holder as described in claim 1, characterized in that, The fastener includes a fixing part and an adhesive part, the adhesive part is bent and bonded to the fixing part, and the fixing part is connected to the first layer partition.

3. The microdialysis pre-test vial holder as described in claim 2, characterized in that, The fasteners are distributed on both sides of the first limiting hole in the width direction of the frame.

4. The microdialysis pre-test vial holder as described in claim 1, characterized in that, The number of the first limiting holes is at least one; The number of the second limiting holes is at least one, and the number is the same as the number of the first limiting holes.

5. The microdialysis pre-test vial holder as described in claim 4, characterized in that, The number of the first limiting holes is 2-10, and the first limiting holes are distributed along the length direction of the frame.

6. The microdialysis pre-test vial holder as described in claim 1, characterized in that, The movable partition is mounted on the upright plate via a slide rail.

7. The microdialysis pre-test vial holder as described in claim 1, characterized in that, The frame is also equipped with handles.

8. The microdialysis pre-test vial holder as described in claim 7, characterized in that, The handle includes a connecting rod and a pull ring. The pull ring is formed at the top of the connecting rod. The connecting rod is fixedly installed at the center of the second partition and extends toward the first partition to penetrate and exceed the first partition.

9. The microdialysis pre-test vial holder as described in claim 7, characterized in that, The handle is made of heat-insulating material.