Reaction device for green synthesis of veterinary drug raw materials

Abstract

The utility model discloses a reaction device for green synthesis of veterinary drug raw materials, which relates to the field of veterinary drug preparation and comprises a reaction tank, the interior of the reaction tank is of a hollow structure, and a stirring mechanism is arranged in the reaction tank in a penetrating manner; a quantity control assembly is arranged on one side of the top of the reaction tank, and a feeding hole is formed in the other side of the reaction tank; a thermal interlayer sleeves the outer side of the reaction tank, a heating mechanism is arranged between the reaction tank and the thermal interlayer, and a discharge port is formed in the bottom of the reaction tank; a supporting frame is arranged at the bottom end of the hot interlayer, and heating openings are symmetrically formed in the bottom of the outer side of the hot interlayer. By arranging the stirring mechanism, after raw materials and auxiliary materials are added into the reaction tank, the stirring mechanism is started to carry out efficient forward and reverse rotation type stirring and wall scraping operation on the reaction tank, and forward and reverse rotation type stirring is adopted, so that the stirring efficiency can be greatly improved, the stirring time can be shortened, and uniform distribution of the materials in the reaction tank can be ensured; therefore, the mixing quality is improved.

Description

Technical Field

[0001] This utility model relates to the field of veterinary drug preparation, specifically to a reaction device for the green synthesis of veterinary drug raw materials. Background Technology

[0002] Veterinary drug raw materials refer to the active pharmaceutical ingredients used in the production of various veterinary drug preparations. Florfenicol, also known as florfenicol or fluorochloramphenicol, is a monofluorinated derivative of florfenicol. It is usually a white crystalline powder, odorless and non-toxic. In the production of florfenicol, the solution is liquid and needs to react with additives and other raw materials. This process requires precise control to reduce material waste and achieve green synthesis. Therefore, a mixed reaction is necessary during the production of florfenicol.

[0003] For example, Chinese patent CN214863504U discloses a florfenicol injection reaction vessel, including a cover, a frame, a vessel body, and a temperature sensor. A controller is installed at one end of the frame, and the vessel body is welded inside the frame. A temperature-regulating sleeve is fixed to the outside of the vessel body. Although this device can perform the florfenicol reaction, the uneven heating of the reaction vessel affects the reaction effect, resulting in poor product quality. In addition, because the stirring shaft is located at the bottom, the reaction rate at the top and bottom is inconsistent, sometimes fast and sometimes slow, which further reduces the overall reaction efficiency.

[0004] Most existing reaction devices cannot guarantee uniform heating of the vessel during stirring; furthermore, they cannot reach the required temperature when high temperatures are needed, nor can they effectively reduce the temperature when cooling is required. This leads to poor reaction results and may affect product quality. In addition, the internal sidewalls of the reaction vessel often require manual cleaning during stirring, which not only increases maintenance costs but also labor costs.

[0005] No effective solutions have yet been proposed to address the problems in the relevant technologies. Utility Model Content

[0006] In view of the problems in the related technologies, this utility model proposes a reaction device for the green synthesis of veterinary drug raw materials, so as to overcome the above-mentioned technical problems existing in the existing related technologies.

[0007] Therefore, the specific technical solution adopted by this utility model is as follows:

[0008] A reaction apparatus for the green synthesis of veterinary drug raw materials includes a reaction vessel with a hollow interior and a stirring mechanism inserted inside. A flow control component is located on one side of the top of the reaction vessel, and a feed inlet is located on the other side. A thermal jacket is fitted around the outside of the reaction vessel, and a heating mechanism is installed between the reaction vessel and the thermal jacket. A discharge port is located at the bottom of the reaction vessel. A support frame is installed at the bottom of the thermal jacket, and heating ports are symmetrically arranged at the bottom of the outer side of the thermal jacket.

[0009] Furthermore, to significantly improve stirring efficiency, reduce stirring time, and ensure uniform distribution of materials within the reaction vessel, thereby improving mixing quality, the stirring mechanism includes a drive shaft inserted inside the reaction vessel. Several linearly arranged anchor-type stirring blocks are positioned on the outer circumference of the drive shaft. A drive gear is fitted at the top of the drive shaft and above the anchor-type stirring blocks. Several driven gears are positioned on the outer circumference of the drive gear, and these driven gears mesh with an internal gear ring. Connecting clips, which are fixedly connected to the drive shaft, are located at both the top and bottom of the internal gear ring. A connecting column is inserted through the middle of each driven gear. The top of the connecting column passes through the connecting clips and connects to the reaction vessel, while the bottom of the connecting column connects to the connecting clip located below. The bottom of the connecting housing has a sliding groove, inside which are sliding balls that mate with the internal gear ring. Several stirring frames are arranged on the outer circumference of the internal gear ring. A dispersing block is located on the side of the stirring frame near the drive shaft, and the dispersing block is staggered from the anchor stirring block. On the other side of the stirring frame are several linearly arranged and symmetrical end blocks, with a retaining shaft between them. A connecting plate is located on the outer circumference of the retaining shaft, and a scraper is connected to the top of the connecting plate. Several inclined connecting frames are located at the bottom of the stirring frame near the drive shaft, with a circular ring at one end. A bearing that mates with the drive shaft is located inside the circular ring. The top of the drive shaft passes through the reaction vessel and connects to the drive motor. A limit ring is located at the bottom of the connecting housing. The retaining shaft and end blocks are connected by bolts. The bottom end of the circular ring is bolted to the bottom end of the bearing. One side of the scraper mates with the inner side wall of the reaction vessel.

[0010] Furthermore, in order to accurately control the amount of material fed into the reactor and improve production efficiency and product quality, the quantity control component includes a control valve located at the top of the reactor, an inlet pipe located at the bottom of the control valve, the inlet pipe passing through the reactor and connected to the inlet port; a circular shell is connected to one end of the control valve, an inlet pipe is located inside the circular shell, and an additive box is connected to the bottom of the inlet pipe and located on the side wall of the reactor, and a water pump connected to the inlet pipe is located inside the additive box.

[0011] Furthermore, in order to improve the reaction rate and reduce energy waste and loss, and reduce production costs, the heating mechanism includes an insulation pad set outside the heat jacket, a number of heat-conducting plates set inside the insulation pad, and a number of linearly equidistant spiral heat-conducting holes opened on the heat-conducting plates; and a heat outlet set at the top of the heat jacket to cooperate with the spiral heat-conducting holes.

[0012] The beneficial effects of this utility model are as follows:

[0013] 1. When conducting veterinary drug reactions, the required raw materials and excipients are accurately weighed according to the formulation and process requirements of the synthesis reaction, and then mixed and reacted using a reaction apparatus. The reaction is carried out by setting up a stirring mechanism, a quantity control component, and a heating mechanism. After the raw materials and excipients are added to the reaction tank, the dosage of the additives is controlled using the quantity control component, ensuring precise control of the material input and improving production efficiency and product quality. Subsequently, the stirring mechanism is activated, performing efficient forward and reverse stirring and wall scraping operations on the reaction tank. This forward and reverse stirring not only greatly improves stirring efficiency and reduces stirring time but also ensures uniform distribution of materials in the reaction tank, thereby improving mixing quality. Simultaneously, while the stirring mechanism is stirring, the heating mechanism can be used to achieve uniform temperature distribution and heating, increasing the reaction rate and reducing energy waste and loss, thus lowering production costs.

[0014] 2. By setting up a stirring mechanism, the drive motor can be started to drive the active gear, driven gear and internal gear ring to ensure smooth power transmission and stirring efficiency. It also drives the stirring frame, scraper, dispersing block and anchor stirring block to ensure that they can stick to the inner wall of the reaction tank during the stirring process, scrape off the material adhering to the wall and avoid material residue.

[0015] 3. By setting up a volume control component, the control valve can control the additives in the additive tank and the flow and time of the additives, so as to ensure the smooth addition of additives and the precise control of the additive dosage; and through the connection of the inlet pipe and the outlet pipe to the control valve, a stable source of additives can be provided.

[0016] 4. By setting up a heating mechanism, the insulation pad can be wrapped around the outside of the reaction vessel, thus providing heat insulation; the setting of the heat-conducting plate and spiral heat-conducting holes helps to transfer heat evenly and ensures a uniform temperature distribution inside the reaction vessel.

[0017] 5. The reaction in this device is carried out under relatively mild conditions, and the operation process is simple and easy. It effectively reduces the total number of reaction steps, lowers production costs, and is suitable for large-scale industrial production. At the same time, it conforms to the current concept of green, environmental protection and energy conservation. Attached Figure Description

[0018] To more clearly illustrate the technical solutions in the embodiments of this utility model or the prior art, the drawings used in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0019] Figure 1 This is a schematic diagram of a reaction apparatus for the green synthesis of veterinary drug raw materials according to an embodiment of the present utility model;

[0020] Figure 2 This is a cross-sectional view of a reaction apparatus for the green synthesis of veterinary drug raw materials according to an embodiment of the present utility model;

[0021] Figure 3 This is a schematic diagram of the flow control component and heating mechanism in a reaction device for the green synthesis of veterinary drug raw materials according to an embodiment of the present invention;

[0022] Figure 4 This is one of the structural schematic diagrams of the stirring mechanism in a reaction device for the green synthesis of veterinary drug raw materials according to an embodiment of the present utility model;

[0023] Figure 5 yes Figure 4 A magnified view of part A.

[0024] Figure 6 This is the second schematic diagram of the stirring mechanism in a reaction device for the green synthesis of veterinary drug raw materials according to an embodiment of this utility model.

[0025] In the picture:

[0026] 1. Reaction vessel; 2. Stirring mechanism; 201. Drive shaft; 202. Anchor-type stirring block; 203. Drive gear; 204. Driven gear; 205. Internal gear ring; 206. Connecting clamp; 207. Connecting column; 208. Sliding groove; 209. Sliding ball; 210. Stirring frame; 211. Dispersing block; 212. End block; 213. Shaft retainer; 214. Connecting plate; 215. Scraper; 216. Inclined connecting frame; 217. Circular ring; 218. 1. Bearing; 219. Drive motor; 220. Limiting ring; 3. Quantity control assembly; 301. Control valve; 302. Inlet pipe; 303. Inlet port; 304. Circular shell; 305. Inlet pipe; 306. Additive box; 307. Water pump; 4. Feed port; 5. Thermal jacket; 501. Heat outlet; 6. Heating mechanism; 601. Insulation pad; 602. Heat-conducting plate; 603. Spiral heat-conducting hole; 7. Discharge port; 8. Support frame; 9. Heating port. Detailed Implementation

[0027] To further illustrate the various embodiments, the present invention provides accompanying drawings, which are part of the disclosure of the present invention. These drawings are mainly used to illustrate the embodiments and can be used in conjunction with the relevant descriptions in the specification to explain the operating principles of the embodiments. With reference to these contents, those skilled in the art should be able to understand other possible implementation methods and the advantages of the present invention. The components in the figures are not drawn to scale, and similar component symbols are usually used to represent similar components.

[0028] According to an embodiment of this utility model, a reaction apparatus for the green synthesis of veterinary drug raw materials is provided.

[0029] The present invention will now be further described in conjunction with the accompanying drawings and specific embodiments, such as... Figures 1-6 As shown, a reaction device for green synthesis of veterinary drug raw materials according to an embodiment of the present invention includes a reaction tank 1. The reaction tank 1 has a hollow internal structure, and a stirring mechanism 2 is inserted inside the reaction tank 1. A flow control component 3 is provided on one side of the top of the reaction tank 1, and a feed inlet 4 is provided on the other side of the reaction tank 1. A thermal jacket 5 is sleeved on the outside of the reaction tank 1, and a heating mechanism 6 is provided between the reaction tank 1 and the thermal jacket 5. A discharge port 7 is provided at the bottom of the reaction tank 1. A support frame 8 is provided at the bottom of the thermal jacket 5, and heating ports 9 are symmetrically arranged at the bottom of the outer side of the thermal jacket 5.

[0030] When a veterinary drug reaction is to be carried out using the above-mentioned technical solution of this utility model, the required raw materials and excipients are accurately weighed according to the formula and process requirements of the synthesis reaction, and then mixed and reacted using a reaction device. The reaction is carried out using a stirring mechanism 2, a quantity control component 3, and a heating mechanism 6. After the raw materials and excipients are added to the reaction tank 1, the dosage of the additives is controlled by the quantity control component 3, so as to accurately control the amount of materials added, thereby improving production efficiency and product quality. Subsequently, the stirring mechanism 2 is started to perform efficient forward and reverse stirring and wall scraping operation on the reaction tank 1. The forward and reverse stirring not only greatly improves the stirring efficiency and reduces the stirring time, but also ensures the uniform distribution of materials in the reaction tank, thereby improving the mixing quality. At the same time, when the stirring mechanism 2 is stirring, the heating mechanism 6 can be used to achieve uniform temperature distribution and uniform heating, thereby increasing the reaction rate and reducing energy waste and loss, and reducing production costs.

[0031] In one embodiment, the stirring mechanism 2 includes a drive shaft 201 inserted inside the reaction vessel 1. Several anchor-type stirring blocks 202 arranged linearly are disposed on the outer circumference of the drive shaft 201. A drive gear 203 is sleeved on the top of the drive shaft 201 and above the anchor-type stirring blocks 202. Several driven gears 204 are disposed on the outer circumference of the drive gear 203. The driven gears 204 cooperate with an internal gear ring 205. Connecting housings 206, which are fixedly connected to the drive shaft 201, are disposed at both the top and bottom of the internal gear ring 205. A connecting post 207 is inserted through the middle of the driven gear 204. The top of the connecting post 207 passes through the connecting housing 206 and connects to the reaction vessel 1. The bottom of the connecting post 207 connects to the connecting housing 206 located below. A sliding groove 208 is provided at the bottom of the connecting housing 206. A groove is provided inside the sliding groove 208 that interacts with the internal gear ring 204. The inner gear ring 205 is equipped with a sliding ball 209; several stirring racks 210 are arranged on the outer circumference of the inner gear ring 205, and a dispersing block 211 is arranged on the side of the stirring rack 210 near the drive shaft 201, and the dispersing block 211 is staggered with the anchor stirring block 202; several linearly arranged and symmetrical end blocks 212 are arranged on the other side of the stirring rack 210, and a retaining shaft 213 is arranged between the end blocks 212. A connecting plate 214 is arranged on the outer circumference of the retaining shaft 213, and a scraper 215 is connected to the top of the connecting plate 214; several inclined connecting frames 216 are arranged at the bottom of the stirring rack 210 and near the drive shaft 201, and a circular ring 217 is arranged at one end of the several inclined connecting frames 216. A bearing 218 that mates with the drive shaft 201 is arranged inside the circular ring 217; the top of the drive shaft 201 passes through the reaction tank 1 and is connected to a drive motor 219. A limit ring 220 is arranged at the bottom of the connecting housing 206. The retaining shaft 213 and the end block 212 are connected by bolts. The bottom end of the circular ring 217 is bolted to the bottom end of the bearing 218. One side of the scraper 215 mates with the inner side wall of the reaction vessel 1, thereby greatly improving the stirring efficiency, reducing the stirring time, and ensuring the uniform distribution of materials in the reaction vessel, thus improving the mixing quality.

[0032] Working principle of stirring mechanism 2: After the required raw materials and auxiliary materials are accurately weighed and added to reaction tank 1, and after the liquid additive is added by the volume control component 3, the drive motor 219 is started to drive the active gear 203, driven gear 204 and internal gear ring 205 to drive the stirring frame 210 and the scraper 215, dispersing block 211 and anchor stirring block 202 on the drive shaft 201. The connecting clamp 206 is fixed to the bottom end of the connecting column 207 of the driven gear 204, and the limiting ring 220 on the connecting clamp 206 limits the stirring frame 210. The top end of the connecting column 207 passes through the connecting clamp 206 and is connected to the reaction tank. 1. The top is fixed, and during rotation, the bottom end of the internal gear ring 205 has a ball bearing 209 and a sliding groove 208 to reduce the friction and damage of the internal gear ring 205. The retaining shaft 213 and the end block 212 are fixed by bolts, and the angle of the scraper 215 on the connecting plate 214 can be manually adjusted and fixed. Multiple inclined connecting brackets 216 extend to the outside of the circular ring 217. The bottom end of the circular ring 217 is fixed to the bottom end of the bearing 218 with bolts to prevent the stirring rack 210 from falling off and the drive shaft 201 from becoming unstable. During movement, the bearing 218 inside the circular ring 217 does not rotate with the drive shaft 201.

[0033] In one embodiment, the above-mentioned quantity control component 3 includes a control valve 301 located at the top of the reaction tank 1, an inlet pipe 302 located at the bottom of the control valve 301, the inlet pipe 302 passing through the reaction tank 1 and connected to the inlet port 303; a circular shell 304 is connected to one end of the control valve 301, an inlet pipe 305 is located inside the circular shell 304, and an additive box 306 is connected to the bottom end of the inlet pipe 305 and located on the side wall of the reaction tank 1. A water pump 307 connected to the inlet pipe 305 is located inside the additive box 306, thereby accurately controlling the amount of material fed in, improving production efficiency and product quality.

[0034] The working principle of the quantity control component 3: After accurately weighing the required raw materials and auxiliary materials, when liquid additives need to be added, the control valve 301 draws the additives from the additive box 306 from the inlet pipe 305 into the inlet pipe 302. The additives are transported to the inlet port 303 through the inlet pipe 302 and finally enter the reaction tank 1. The external inlet pipe 305 is protected by a circular shell 304.

[0035] In one embodiment, the heating mechanism 6 includes a heat insulation pad 601 disposed outside the heat jacket 5, a plurality of heat-conducting plates 602 disposed inside the heat insulation pad 601, and a plurality of linearly equidistant spiral heat-conducting holes 603 disposed on the heat-conducting plates 602; the top of the heat jacket 5 is provided with a heat outlet 501 that cooperates with the spiral heat-conducting holes 603, thereby improving the reaction rate and reducing energy waste and loss, and reducing production costs.

[0036] The working principle of the heating mechanism 6: When a mixing reaction is required to accelerate the reaction, the heat insulation pad 601 is wrapped around the outside of the reaction vessel 1 to keep it warm. The heat enters the interior of the heat insulation pad 601 through the heating port 9. The heating port 9 heats the gas evenly from multiple heat-conducting plates 602 and spiral heat-conducting holes 603. Then, when the internal hot air reaches the top, it is released through the heat outlet 501 to prevent the internal heat from being too high and damaging the device.

[0037] To facilitate understanding of the above-mentioned technical solutions of this utility model, the working principle or operation method of this utility model in actual process will be described in detail below.

[0038] In practical applications, when a veterinary drug reaction is to be carried out, the required raw materials and excipients are accurately weighed according to the formulation and process requirements of the synthesis reaction. The reaction temperature is controlled between 100℃ and 150℃, and the acylation reaction is carried out under the action of additives. When adding liquid additives, the control valve 301 of the flow control component 3 is used to draw the additives from the additive box 306 into the inlet pipe 302 through the inlet pipe 305. The additives are then transported to the inlet 303 through the inlet pipe 302 and enter the reaction tank 1 (the working principle of the flow control component 3 is as described above). The drive motor 219 of the stirring mechanism 2 drives the drive gear 203, the driven gear 204, and the internal gear ring 205. The stirring rack 210, driven by the coordinated action of the scraper 215, dispersing block 211, and anchor stirring block 202 on the drive shaft 201, mixes and reacts the raw materials, auxiliary materials, and additives (the working principle of the stirring mechanism 2 is as described above). During stirring, the generated temperature is covered by the heat insulation pad 601 of the heating mechanism 6, which surrounds the reaction tank 1. The heating port 9 provides uniform heating through multiple heat-conducting plates 602 and spiral heat-conducting holes 603. When the internal hot air reaches the top, it is released through the heat outlet 501. The air circulation within the reaction tank 1 is used for heat preservation and uniform heating (the working principle of the heating mechanism 6 is as described above). The product is then manually collected from the discharge port 7. Furthermore, the reaction in this device is carried out under relatively mild conditions, the operation is simple and easy, effectively reducing the total number of reaction steps, lowering production costs, making it suitable for large-scale industrial production, and conforming to the current concept of green environmental protection and energy conservation.

[0039] In this utility model, unless otherwise explicitly specified and limited, the terms "installation", "setting", "connection", "fixing", "screw connection", etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal connection of two components or the interaction between two components. Unless otherwise explicitly limited, those skilled in the art can understand the specific meaning of the above terms in this utility model according to the specific circumstances.

[0040] The above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. A reaction apparatus for the green synthesis of veterinary drug raw materials, comprising a reaction vessel (1), characterized in that, The reaction vessel (1) has a hollow structure inside, and a stirring mechanism (2) is interspersed inside the reaction vessel (1). A flow control component (3) is provided on one side of the top of the reaction vessel (1), and a feed inlet (4) is provided on the other side of the reaction vessel (1). The reaction vessel (1) is fitted with a heat jacket (5) on the outside, and a heating mechanism (6) is provided between the reaction vessel (1) and the heat jacket (5). The bottom of the reaction vessel (1) is provided with a discharge port (7). The bottom end of the thermal interlayer (5) is provided with a support frame (8), and heating ports (9) are symmetrically provided on the bottom of the outer side of the thermal interlayer (5).

2. The reaction apparatus for the green synthesis of veterinary drug raw materials according to claim 1, characterized in that, The stirring mechanism (2) includes a drive shaft (201) that is inserted inside the reaction vessel (1), and a number of anchor-type stirring blocks (202) arranged linearly are provided on the outer circumference of the drive shaft (201). A drive gear (203) is sleeved on the top of the drive shaft (201) and above the anchor-type stirring block (202). Several driven gears (204) are provided on the outer circumference of the drive gear (203). The driven gears (204) cooperate with the internal gear ring (205). The top and bottom of the internal gear ring (205) are provided with connecting clips (206) that are fixedly connected to the drive shaft (201). A connecting post (207) is inserted through the middle of the driven gear (204). The top end of the connecting post (207) passes through the connecting housing (206) and is connected to the reaction vessel (1). The bottom end of the connecting post (207) is connected to the connecting housing (206) located below. A sliding groove (208) is provided at the bottom of the connecting housing (206). A sliding ball (209) that cooperates with the internal gear ring (205) is provided inside the sliding groove (208). The inner gear ring (205) has several stirring racks (210) arranged on its outer circumference. The stirring rack (210) has a dispersing block (211) arranged on the side near the drive shaft (201), and the dispersing block (211) is offset from the anchor stirring block (202). On the other side of the stirring rack (210), there are a number of linearly arranged and symmetrical end blocks (212), and a retaining shaft (213) is provided between the end blocks (212). A connecting plate (214) is provided on the outer circumference of the retaining shaft (213), and a scraper (215) is connected to the top of the connecting plate (214). The bottom of the stirring rack (210) and near the drive shaft (201) is provided with a plurality of inclined connecting frames (216), and one end of the plurality of inclined connecting frames (216) is provided with a circular ring (217), and the inside of the circular ring (217) is provided with a bearing (218) that cooperates with the drive shaft (201). The top of the drive shaft (201) passes through the reaction vessel (1) and is connected to a drive motor (219). The bottom of the connecting housing (206) is provided with a limit ring (220).

3. The reaction apparatus for the green synthesis of veterinary drug raw materials according to claim 2, characterized in that, The clasp (213) and the end block (212) are connected by bolts.

4. The reaction apparatus for the green synthesis of veterinary drug raw materials according to claim 2, characterized in that, The bottom end of the circular ring (217) is bolted to the bottom end of the bearing (218).

5. The reaction apparatus for the green synthesis of veterinary drug raw materials according to claim 2, characterized in that, The scraper (215) is fitted with the inner sidewall of the reaction vessel (1) on one side.

6. The reaction apparatus for the green synthesis of veterinary drug raw materials according to claim 1, characterized in that, The quantity control component (3) includes a control valve (301) located at the top of the reaction vessel (1), and an inlet pipe (302) located at the bottom of the control valve (301). The inlet pipe (302) passes through the reaction vessel (1) and is connected to the inlet port (303). One end of the control valve (301) is connected to a circular shell (304), and an inlet pipe (305) is provided inside the circular shell (304). The bottom end of the inlet pipe (305) and located on the side wall of the reaction vessel (1) is connected to an additive box (306), and a water pump (307) connected to the inlet pipe (305) is provided inside the additive box (306).

7. The reaction apparatus for the green synthesis of veterinary drug raw materials according to claim 1, characterized in that, The heating mechanism (6) includes a heat insulation pad (601) disposed outside the heat jacket (5), and a plurality of heat-conducting plates (602) are disposed on the inner side of the heat insulation pad (601), and a plurality of linearly equidistant spiral heat-conducting holes (603) are opened on the heat-conducting plates (602). The top of the thermal interlayer (5) is provided with a heat outlet (501) that cooperates with the spiral heat-conducting hole (603).

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