Paracetamol dihydrocodeine tablet particle forming device

Abstract

The utility model discloses a paracetamol dihydrocodeine tablet particle forming device, which belongs to the technical field of medicine processing, and comprises a granulator, the output end of the granulator is fixedly connected with a discharge port, the top of the granulator is fixedly connected with a mixing tank, and the mixing tank is connected with the discharge port. A smashing mechanism is arranged at the position, close to the top end, of the interior of the mixing tank, a spraying pipe and a supporting base are fixedly connected to the position, close to the upper portion, of the interior of the mixing tank, a double-shaft motor is fixedly connected to the center of the interior of the supporting base, and a set of discharging rollers are fixedly connected to the output end of the upper portion of the double-shaft motor. The raw materials can be uniformly discharged, the mixing effect of the raw materials is improved in cooperation with the stable mixing assembly, the solid raw materials can be subjected to smashing pretreatment through the smashing assembly, the caking problem of the solid raw materials is solved, and the raw material mixing and stirring effect is further improved.

Description

Technical Field

[0001] This utility model relates to the field of pharmaceutical processing technology, and more specifically, to a granulation device for acetaminophen dihydrocodeine tablets. Background Technology

[0002] Acetaminophen dihydrocodeine tablets are analgesics composed of two drugs, dihydrocodeine tartrate and acetaminophen. They work synergistically through different mechanisms of action to achieve analgesia. Granulators are one of the commonly used pieces of equipment in the pharmaceutical production and processing process. Their main function is to process drugs into granules so that they can be compressed into tablets later.

[0003] Based on the above, the inventors have discovered that existing granulators mainly consist of a mixing component and a granulation component. The mixing component mixes and stirs the pharmaceutical raw materials, but solid raw materials may clump due to unexpected situations, resulting in poor mixing and stirring effects. Therefore, in view of this, the inventors have studied and improved the existing structure to provide a granulation device for acetaminophen dihydrocodeine tablets, aiming to achieve a more practical purpose. Utility Model Content

[0004] 1. Technical problems to be solved

[0005] To address the problems existing in the prior art, the purpose of this utility model is to provide a granulation device for acetaminophen dihydrocodeine tablets. This solution is equipped with a guiding component, which can make the raw materials feed evenly. Combined with a stable mixing component, it can improve the mixing effect of the raw materials. Furthermore, a crushing component can be set up to crush and pre-treat the solid raw materials, reduce the problem of solid raw materials clumping, and further improve the mixing effect of the raw materials.

[0006] 2. Technical Solution

[0007] To solve the above problems, the present invention adopts the following technical solution.

[0008] A granulation device for acetaminophen dihydrocodeine tablets includes a granulator. The output end of the granulator is fixedly connected to a discharge port, and the top of the granulator is fixedly connected to a mixing tank. A crushing mechanism is provided inside the mixing tank near the top, and a spray pipe and a support base are fixedly connected inside the mixing tank near the top. A dual-shaft motor is fixedly connected in the center of the support base. A set of feeding rollers is fixedly connected to the output end above the dual-shaft motor, and a set of stirring rollers is fixedly connected to the output end below the dual-shaft motor. The tops of several stirring rollers are fixedly connected to the same guide ring.

[0009] The crushing mechanism includes a drive motor and a pair of crushing rollers. One end of each crushing roller is fixedly connected to a toothed ring, and baffles and scrapers are provided on both the upper and lower sides of the crushing rollers.

[0010] Furthermore, a discharge valve is fixedly connected at the connection between the granulator and the mixing tank, and the spray pipe is located above the support base, with the input end of the spray pipe penetrating through the side of the mixing tank.

[0011] Furthermore, the support base is tapered, with the bottom surface of the feed roller in contact with the top surface of the support base.

[0012] Furthermore, the guide ring is located on the bottom surface of the support base near the inside, and the guide ring is movably connected to the support base.

[0013] Furthermore, the drive motor, baffle, and scraper are all fixedly connected to the mixing tank, while the crushing roller is movably connected to the mixing tank.

[0014] Furthermore, the two gear rings are meshed together, and the output end of the drive motor passes through the mixing tank and is fixedly connected to the adjacent crushing roller.

[0015] Furthermore, both the baffle and the scraper are inclined, and the top of the scraper is in contact with the outer surface of the adjacent crushing roller.

[0016] 3. Beneficial effects

[0017] Compared with existing technologies, the advantages of this utility model are:

[0018] (1) This solution guides the raw materials through the support base, so that they enter the bottom of the mixing tank evenly. The feeding roller is used to increase the feeding speed. Then the mixing roller is used to mix the raw materials. The guide ring ensures the rotational stability of the mixing roller. Compared with the existing technology, the setting of the guiding component can make the raw materials feed evenly. With the stable mixing component, the mixing effect of the raw materials is improved.

[0019] (2) By setting up a crushing mechanism, the baffle limits the feeding direction of the raw material, so that it falls between two crushing rollers. Then, through the cooperation of two toothed rings, the two crushing rollers rotate synchronously in opposite directions, thereby realizing the crushing treatment of solid raw materials. The scraper cleans the raw material residue adhering to the surface of the crushing rollers, reducing waste. Compared with the existing technology, setting up a crushing component can pre-treat the solid raw materials, reduce the problem of solid raw material agglomeration, and further improve the effect of raw material mixing. Attached Figure Description

[0020] Figure 1 This is a schematic diagram of the overall structure of this utility model;

[0021] Figure 2 This is a schematic diagram of the internal structure of the mixing tank of this utility model;

[0022] Figure 3 This is a schematic diagram showing the positional relationship between the feeding roller and the mixing roller of this utility model;

[0023] Figure 4 This is a schematic diagram of the crushing mechanism of this utility model.

[0024] The following are the labels in the diagram: 1. Granulator; 2. Discharge port; 3. Mixing tank; 4. Feed valve; 5. Crushing mechanism; 6. Spray pipe; 7. Support base; 8. Dual-shaft motor; 9. Feed roller; 10. Mixing roller; 11. Guide ring; 12. Drive motor; 13. Crushing roller; 14. Toothed ring; 15. Baffle; 16. Scraper. Detailed Implementation

[0025] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present utility model. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. All other embodiments obtained by those skilled in the art based on the embodiments of the present utility model without creative effort are within the protection scope of the present utility model.

[0026] Example:

[0027] Please see Figure 1-4 A granulation device for acetaminophen dihydrocodeine tablets includes a granulator 1. The output end of the granulator 1 is fixedly connected to a discharge port 2, and the top of the granulator 1 is fixedly connected to a mixing tank 3. The mixing tank 3 is equipped with a crushing mechanism 5 near the top, and the mixing tank 3 is fixedly connected to a spray pipe 6 and a support base 7 near the top. The support base 7 is fixedly connected to a dual-shaft motor 8 in the center. The output end above the dual-shaft motor 8 is fixedly connected to a set of feeding rollers 9, and the output end below the dual-shaft motor 8 is fixedly connected to a set of stirring rollers 10. The tops of several stirring rollers 10 are fixedly connected to the same guide ring 11.

[0028] The crushing mechanism 5 includes a drive motor 12 and a pair of crushing rollers 13. One end of the crushing roller 13 is fixedly connected to a toothed ring 14, and baffles 15 and scrapers 16 are provided on both the upper and lower sides of the crushing roller 13. The crushing mechanism 5 is provided for crushing and pre-treatment of solid raw materials.

[0029] See Figure 1 A discharge valve 4 is fixedly connected at the connection between the granulator 1 and the mixing tank 3. The spray pipe 6 is located above the support base 7, and the input end of the spray pipe 6 passes through the side of the mixing tank 3, and liquid raw materials are transported through the spray pipe 6.

[0030] See Figure 2 The support base 7 is cone-shaped, and the bottom surface of the feeding roller 9 is in contact with the top surface of the support base 7. The crushed solid material slides down the support base 7 and the feeding speed is increased by the feeding roller 9.

[0031] See Figure 3 The guide ring 11 is located on the bottom surface of the support base 7 and is movably connected to the support base 7. When the dual-shaft motor 8 is started, it drives the feeding roller 9 and the stirring roller 10 to rotate synchronously. The stirring roller 10 performs the mixing of the pharmaceutical raw materials. The guide ring 11 ensures the rotational stability of the stirring roller 10.

[0032] See Figure 4 The drive motor 12, baffle 15 and scraper 16 are all fixedly connected to the mixing tank 3. The crushing roller 13 is movably connected to the mixing tank 3. Solid raw materials are fed into the mixing tank 3. The baffle 15 limits the feeding direction of the raw materials so that they fall between the two crushing rollers 13.

[0033] See Figure 4 Two toothed rings 14 are meshed and connected. The output end of the drive motor 12 passes through the mixing tank 3 and is fixedly connected to the adjacent crushing roller 13. When the drive motor 12 is started, it drives the corresponding crushing roller 13 to rotate. Through the cooperation of the two toothed rings 14, the other crushing roller 13 rotates synchronously in the opposite direction, thereby realizing the crushing of solid raw materials.

[0034] See Figure 2 Both the baffle 15 and the scraper 16 are inclined, and the top of the scraper 16 is in contact with the outer surface of the adjacent crushing roller 13. The scraper 16 cleans the raw material residue adhering to the surface of the crushing roller 13, reducing waste.

[0035] In use: Solid raw materials are fed into the mixing tank 3. The baffle 15 limits the feeding direction of the raw materials, causing them to fall between the two crushing rollers 13. The drive motor 12 is started to drive the corresponding crushing roller 13 to rotate. The two toothed rings 14 cooperate with each other to make the other crushing roller 13 rotate synchronously in the opposite direction, thereby realizing the crushing of solid raw materials. The scraper 16 cleans the raw material residue adhering to the surface of the crushing roller 13 to reduce waste. After that, the solid raw materials fall above the support base 7. The dual-shaft motor 8 is started to drive the feeding roller 9 and the stirring roller 10 to rotate synchronously. The crushed solid material slides down the support base 7. The feeding roller 9 increases the feeding speed. At the same time, the spray pipe 6 delivers liquid raw materials. Then, the stirring roller 10 mixes the raw materials. The guide ring 11 ensures the rotational stability of the stirring roller 10. After the raw materials are mixed, they are sent into the granulator 1 through the feeding valve 4 to complete the granulation of the medicine. Then, the medicine granules are discharged from the discharge port 2.

[0036] Finally, it should be noted that in the description of this utility model, the terms "vertical," "upper," "lower," "horizontal," etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model.

[0037] In the description of this utility model, it should also be noted that, unless otherwise explicitly specified and limited, the terms "set," "install," "connect," and "link" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model according to the specific circumstances.

[0038] The above description is merely a preferred embodiment of this utility model; however, the protection scope of this utility model is not limited thereto. Any equivalent substitutions or modifications made by those skilled in the art within the technical scope disclosed in this utility model, based on the technical solution and its improved concept, should be included within the protection scope of this utility model.

Claims

1. A granulation apparatus for acetaminophen dihydrocodeine tablets, comprising a granulator (1), wherein the output end of the granulator (1) is fixedly connected to a discharge port (2), and a mixing tank (3) is fixedly connected to the top of the granulator (1), characterized in that: The mixing tank (3) is equipped with a crushing mechanism (5) at the top inside, and a spray pipe (6) and a support base (7) are fixedly connected to the upper part of the mixing tank (3). A dual-axis motor (8) is fixedly connected in the center inside the support base (7). A set of feeding rollers (9) is fixedly connected to the output end above the dual-axis motor (8), and a set of stirring rollers (10) is fixedly connected to the output end below the dual-axis motor (8). The top of several stirring rollers (10) is fixedly connected to the same guide ring (11). The crushing mechanism (5) includes a drive motor (12) and a pair of crushing rollers (13). One end of the crushing roller (13) is fixedly connected to a toothed ring (14), and baffles (15) and scrapers (16) are provided on both the upper and lower sides of the crushing roller (13).

2. A device for forming granules of paracetamol and dihydrocodeine phosphate according to claim 1, characterised in that: A feed valve (4) is fixedly connected at the connection between the granulator (1) and the mixing tank (3). The spray pipe (6) is located above the support base (7), and the input end of the spray pipe (6) passes through the side of the mixing tank (3).

3. The apparatus for forming granules of paracetamol and dihydrocodeine bitartrate according to claim 1, wherein: The support base (7) is tapered, and the bottom surface of the feed roller (9) is in contact with the top surface of the support base (7).

4. The device for forming granules of paracetamol and dihydrocodeine phosphate according to claim 1, characterized in that: The guide ring (11) is located on the bottom surface of the support base (7) and is movably connected to the support base (7).

5. The apparatus for forming granules of paracetamol and dihydrocodeine bitartrate according to claim 1, wherein: The drive motor (12), baffle (15) and scraper (16) are all fixedly connected to the mixing tank (3), and the crushing roller (13) is movably connected to the mixing tank (3).

6. The device for forming granules of paracetamol and dihydrocodeine phosphate according to claim 1, characterized in that: The two gear rings (14) are meshed together, and the output end of the drive motor (12) passes through the mixing tank (3) and is fixedly connected to the adjacent crushing roller (13).

7. The device for forming granules of paracetamol and dihydrocodeine phosphate according to claim 1, characterized in that: Both the baffle (15) and the scraper (16) are inclined, and the top of the scraper (16) is in contact with the outer surface of the adjacent crushing roller (13).

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