Parallel distributed microfluidic pipeline device

Abstract

The utility model discloses a parallel distribution type micro-fluidic pipeline device which comprises a base, a shell is installed on the top of the base in a sliding mode, a micro-fluidic chip is fixedly installed on the top of the shell, a second linear driving mechanism used for driving the shell is installed on the base, a rack is fixedly installed on the top of the base, and a first linear driving mechanism used for driving the shell is installed on the rack. The rack is connected with a trapezoidal block through a first linear driving mechanism; through the arrangement of the first linear driving mechanism, the trapezoidal block, the transmission mechanism, the valve mechanism and the plurality of micro-pipelines, a lysis solution, a cleaning solution, an eluent, a PCR reagent and a diluent which are stored in the first liquid storage tank, the second liquid storage tank, the third liquid storage tank, the fourth liquid storage tank and the fifth liquid storage tank can be sequentially mixed with a sample and the like in the first PCR tube; and liquid in the first PCR tube is pumped into the waste liquid tank or the second PCR tube to synchronously carry out a plurality of times of detection tests, so that the detection efficiency is effectively improved, and the use effect is good.

Description

Technical Field

[0001] This utility model relates to the field of microfluidics technology, specifically a parallel distributed microfluidic pipeline device. Background Technology

[0002] Microfluidic chip technology, through miniaturization and integration, condenses traditional laboratory functions into centimeter or millimeter-scale chips, covering multiple disciplines and scenarios. In the field of biomedical detection, microfluidic chips can automate steps such as sample lysis, mixing, extraction, dilution, and incubation, greatly simplifying the sample preparation process and improving detection efficiency.

[0003] However, most of the microfluidic chips currently in use only have a single channel, which is inefficient when batch testing or experimentation is required. Therefore, we propose a parallel distributed microfluidic pipeline device. Utility Model Content

[0004] The purpose of this invention is to provide a parallel distributed microfluidic pipeline device to solve the problems mentioned in the background art.

[0005] To achieve the above objectives, this utility model provides the following technical solution:

[0006] A parallel distributed microfluidic pipeline device includes a base, a housing slidably mounted on the top of the base, a microfluidic chip fixedly mounted on the top of the housing, and a second linear drive mechanism for driving the housing mounted on the base. A frame is fixedly mounted on the top of the base, and a trapezoidal block is connected to the frame via a first linear drive mechanism. The microfluidic chip passes through the inside of the frame, and five valve mechanisms are provided on the microfluidic chip. Five transmission mechanisms are provided on the frame at the moving path of the trapezoidal block, with each transmission mechanism corresponding to one of the valve mechanisms. The top surface of the microfluidic chip has a first, second, third, fourth, and fifth liquid storage tank. The microfluidic chip has several microchannels, and the bottom of the microfluidic chip has a second flow channel and five first... The flow channel has a valve mechanism whose inlet end is connected to the corresponding first flow channel and whose outlet end is connected to the second flow channel. The inner bottom of the first, second, third, fourth, and fifth liquid storage tanks is provided with a first through hole, the bottom of which is connected to the corresponding first flow channel. Several microchannels are connected to the second flow channel. The microfluidic chip is provided with several first connectors, waste liquid tanks, and second connectors, all of which are connected to the corresponding flow channels. A first PCR tube is installed on each of the first connectors, and a second PCR tube is installed on each of the second connectors. A first air pump, a second air pump, a third air pump, and a fourth air pump are installed on the housing, all of which are connected to the microchannels.

[0007] As a further embodiment of this utility model: the transmission mechanism includes a guide rod that is slidably mounted on the frame, a first spring is sleeved on the outer wall of the guide rod inside the frame, a force-bearing block is fixedly connected to the top of the guide rod, and a top rod is fixedly connected to the bottom of the guide rod.

[0008] As a further embodiment of this utility model: the valve mechanism includes a valve seat fixedly embedded in the bottom of the microfluidic chip, a valve cavity is formed at the top of the valve seat, and a vent hole communicating with the valve cavity is formed at the bottom of the valve seat. A valve stem is slidably mounted on the microfluidic chip at the corresponding position of each valve cavity. A second spring is sleeved on the outer wall of the valve stem, and the lower end of the valve stem is slidably mounted in the corresponding valve cavity. An annular groove is formed on the outer wall of the valve stem located in the valve cavity. A first connecting hole and a second connecting hole communicating with the valve cavity are formed on the two outer walls of the valve seat respectively. A first groove and a second groove are formed at the bottom of the microfluidic chip at the corresponding position of each valve seat. The first groove communicates with the corresponding first flow channel and the first connecting hole, and the second groove communicates with the second flow channel and the corresponding second connecting hole.

[0009] As a further embodiment of this utility model: the microchannel includes a plurality of fifth, sixth, ninth, eleventh, and fourteenth channels disposed on the top of the microfluidic chip; a plurality of fourth, seventh, tenth, and twelfth channels are formed on the bottom of the microfluidic chip; a plurality of third, fifth, sixth, seventh, eighth, ninth, tenth, eleventh, twelfth, thirteenth, fourteenth, and fifteenth through holes are provided on the microfluidic chip; the two ends of the fourth channel are connected to the corresponding third and fifth through holes; the two ends of the fifth channel are connected to the corresponding fifth and sixth through holes; and the two ends of the sixth channel are connected to the corresponding seventh and eighth through holes. The seventh flow channel is connected to the corresponding eighth and ninth through holes at both ends. The ninth flow channel is connected to the corresponding tenth and eleventh through holes at both ends. The tenth flow channel is connected to the corresponding eleventh and twelfth through holes at both ends. The twelfth through hole is connected to the corresponding waste liquid tank at both ends. The eleventh flow channel is connected to the corresponding thirteenth and fourteenth through holes at both ends. The twelfth flow channel is connected to the corresponding fourteenth and fifteenth through holes at both ends. The fifteenth through hole and the second connector are both connected to the corresponding fourteenth flow channel. The sixth, seventh, tenth, and thirteenth through holes are all connected to the corresponding first connector. A catheter is installed in both the tenth and thirteenth through holes. The catheter is located in the corresponding first PCR tube.

[0010] As a further embodiment of this utility model: the top of the microfluidic chip is provided with a third flow channel, an eighth flow channel, a thirteenth flow channel, and a fifteenth flow channel. The microfluidic chip is provided with a first connection hole, a second connection hole, a third connection hole, and a fourth connection hole. The first connection hole and each of the third through holes are connected to the third flow channel. The second connection hole and each of the waste liquid tanks are connected to the fifteenth flow channel. The third connection hole and each of the ninth through holes are connected to the eighth flow channel. The fourth connection hole and each of the fourteenth flow channels are connected to the thirteenth flow channel. The suction end of the first air pump is connected to the first connection hole through a hose. The suction end of the second air pump is connected to the second connection hole through a hose. The suction end of the third air pump is connected to the third connection hole through a hose. The suction end of the fourth air pump is connected to the fourth connection hole through a hose. One-way valves are installed at the third through hole, the ninth through hole, the twelfth through hole, and the fifteenth through hole.

[0011] Compared with the prior art, the beneficial effects of this utility model are:

[0012] This invention, by setting up a first linear drive mechanism, a trapezoidal block, a transmission mechanism, a valve mechanism, and several microchannels, can sequentially mix the lysis buffer, washing buffer, elution buffer, PCR reagent, and diluent stored in the first, second, third, fourth, and fifth storage tanks with the sample in the first PCR tube, and then draw the liquid in the first PCR tube into a waste tank or a second PCR tube to simultaneously perform several detection experiments, thereby effectively improving detection efficiency and achieving good results. Attached Figure Description

[0013] Figure 1 This is a schematic diagram of a parallel distributed microfluidic pipeline device.

[0014] Figure 2 This is a schematic diagram of the rear structure of a parallel distributed microfluidic pipeline device.

[0015] Figure 3 This is a schematic diagram of the trapezoidal block structure in a parallel distributed microfluidic pipeline device.

[0016] Figure 4 This is a schematic diagram of the internal structure of the shell in a parallel distributed microfluidic pipeline device.

[0017] Figure 5 This is a schematic diagram of the conduit structure in a parallel distributed microfluidic pipeline device.

[0018] Figure 6 This is a cross-sectional view of a microfluidic chip in a parallel distributed microfluidic pipeline device.

[0019] Figure 7 This is a schematic diagram of the top structure of a microfluidic chip in a parallel distributed microfluidic pipeline device.

[0020] Figure 8 This is a schematic diagram of the bottom structure of a microfluidic chip in a parallel distributed microfluidic pipeline device.

[0021] Figure 9 for Figure 8 Enlarged view of point A in the middle.

[0022] The components include: base 1, frame 2, first linear drive mechanism 3, trapezoidal block 4, guide rod 5, force-bearing block 6, first spring 7, top rod 8, second linear drive mechanism 9, housing 10, microfluidic chip 11, first liquid storage tank 12, second liquid storage tank 13, third liquid storage tank 14, fourth liquid storage tank 15, fifth liquid storage tank 16, first through hole 17, first flow channel 18, valve mechanism 19, valve seat 20, first groove 21, second groove 22, valve cavity 23, vent hole 24, first connecting hole 25, second connecting hole 26, valve stem 27, annular groove 28, second spring 29, second flow channel 30, second through hole 31, third flow channel 32, third through hole 33, fourth flow channel 34, fifth through hole 35, fifth flow channel 36, and sixth through hole 37. 1. First connector 38, 7th through hole 39, 6th flow channel 40, 8th through hole 41, 7th flow channel 42, 9th through hole 43, 8th flow channel 44, 10th through hole 45, 9th flow channel 46, 11th through hole 47, 10th flow channel 48, 12th through hole 49, waste liquid tank 50, 13th through hole 51, 11th flow channel 52, 14th through hole 53, 12th flow channel 54, 15th through hole 55, 13th flow channel 56, 14th flow channel 57, 2nd connector 58, 1st air pump 59, 2nd air pump 60, 3rd air pump 61, 4th air pump 62, 1st connecting hole 63, 15th flow channel 64, 2nd connecting hole 65, 3rd connecting hole 66, 4th connecting hole 67, conduit 68, 1st PCR tube 69, 2nd PCR tube 70. Detailed Implementation

[0023] To make the technical problem to be solved, the technical solution, and the beneficial effects of this utility model clearer, the present utility model will be further described in detail below with reference to the embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the present utility model and are not intended to limit the present utility model.

[0024] It should be noted that when a component is referred to as being "fixed to" or "set on" another component, it can be directly on or indirectly on that other component. When a component is referred to as being "connected to" another component, it can be directly connected to or indirectly connected to that other component.

[0025] It should be understood that the terms "upper", "lower", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", and "outer" indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation in the specification, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model.

[0026] Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature.

[0027] Please see Figures 1-9 In this embodiment of the present invention, a parallel distributed microfluidic pipeline device includes a base 1, a housing 10 slidably mounted on the top of the base 1, and a microfluidic chip 11 fixedly mounted on the top of the housing 10. The microfluidic chip 11 is composed of a substrate made of PDMS or PMMA and several glass plates, with the glass plates embedded on both sides of the substrate to seal the flow channels on the substrate. A second linear drive mechanism 9 for driving the housing 10 is mounted on the base 1, and a frame 2 is fixedly mounted on the top of the base 1, and the frame 2 is connected by a first linear drive mechanism. Mechanism 3 is connected to trapezoidal block 4. The first linear drive mechanism 3 consists of a lead screw driven by a servo motor, a ball screw nut, and a guide rail. The microfluidic chip 11 passes through the inside of the frame 2. Five valve mechanisms 19 are provided on the microfluidic chip 11. Five transmission mechanisms are provided on the frame 2 at the moving path of trapezoidal block 4, and the transmission mechanisms correspond one-to-one with the valve mechanisms 19. The top surface of the microfluidic chip 11 has a first liquid storage tank 12, a second liquid storage tank 13, a third liquid storage tank 14, a fourth liquid storage tank 15, and a fifth liquid storage tank 16. The microfluidic chip 11 is equipped with several microchannels. At its bottom, the microfluidic chip 11 has a second flow channel 30 and five first flow channels 18. The inlet end of the valve mechanism 19 is connected to the corresponding first flow channel 18, and the outlet end of the valve mechanism 19 is connected to the second flow channel 30. The inner bottom of the first liquid storage tank 12, second liquid storage tank 13, third liquid storage tank 14, fourth liquid storage tank 15, and fifth liquid storage tank 16 each has a first through hole 17, and the bottom end of the first through hole 17 is connected to the corresponding first flow channel 18. All the microchannels are connected to the second flow channel 30. The microfluidic chip 11 is provided with a plurality of first connectors 38, waste liquid tanks 50 and second connectors 58. The first connectors 38, waste liquid tanks 50 and second connectors 58 are connected to corresponding flow channels. A first PCR tube 69 is installed on each of the first connectors 38 and a second PCR tube 70 is installed on each of the second connectors 58. A first air pump 59, a second air pump 60, a third air pump 61 and a fourth air pump 62 are installed on the housing 10. The first air pump 59, the second air pump 60, the third air pump 61 and the fourth air pump 62 are all connected to the microtubes.

[0028] By adopting the above-described scheme, this utility model allows for the storage of lysis buffer, washing buffer, elution buffer, PCR reagent, and diluent in the first storage tank 12, second storage tank 13, third storage tank 14, fourth storage tank 15, and fifth storage tank 16, respectively. Samples, positive controls, negative controls, and quality control materials are placed in each first PCR tube 69. Then, the trapezoidal block 4 is moved by the first linear drive mechanism, which opens the corresponding valve mechanism 19 via the transmission mechanism. This allows the lysis buffer to be driven by the air pump to flow in parallel through each microtube to the corresponding first PCR tube 69. The sample is mixed with the contents of each of the first PCR tubes 69 in a PCR tube. Then, under the action of an air pump, the waste liquid is transported through a microchannel to a waste liquid tank 50. The valve mechanism 19 is opened in sequence to mix the washing solution, elution solution, PCR reagent, and diluent with the sample in sequence. Finally, DNA is extracted. The DNA is transported through an air pump to a second PCR tube 70 and mixed with the probe for PCR reaction and real-time fluorescence detection. By setting multiple microchannels, several detection experiments can be performed simultaneously, thereby effectively improving detection efficiency and achieving good results.

[0029] Specific combination Figure 3 In one embodiment of the present invention, the transmission mechanism includes a guide rod 5 that is slidably mounted on the frame 2. The outer wall of the guide rod 5 located inside the frame 2 is fitted with a first spring 7. The top end of the guide rod 5 is fixedly connected to a force-bearing block 6, and the bottom end of the guide rod 5 is fixedly connected to a top rod 8.

[0030] When the trapezoidal block 4 contacts the force-bearing block 6 under the drive of the first linear drive mechanism, it will push the corresponding guide rod 5 and push rod 8 to move downward to open the valve mechanism. When the trapezoidal block 4 disengages from the force-bearing block 6, the force-bearing block 6 will reset upward under the action of the first spring 7 to close the corresponding valve mechanism.

[0031] Specific combination Figure 3 , Figure 6 and Figure 9Based on the previous embodiment, the valve mechanism 19 further includes a valve seat 20 fixedly embedded in the bottom of the microfluidic chip 11. The top of the valve seat 20 has a valve cavity 23, and the bottom of the valve seat 20 has a vent hole 24 communicating with the valve cavity 23. A valve stem 27 is slidably mounted on the microfluidic chip 11 at a corresponding position to each valve cavity 23. A second spring 29 is sleeved on the outer wall of the valve stem 27, and the lower end of the valve stem 27 is slidably mounted in the corresponding valve cavity 23. Inside the valve stem 27, an annular groove 28 is formed on the outer wall of the valve cavity 23. The two outer walls of the valve seat 20 are respectively provided with a first connecting hole 25 and a second connecting hole 26 that communicate with the valve cavity 23. The bottom of the microfluidic chip 11 is provided with a first groove 21 and a second groove 22 at the corresponding positions of each valve seat 20. The first groove 21 communicates with the corresponding first flow channel 18 and the first connecting hole 25. The second groove 22 communicates with the second flow channel 30 and the corresponding second connecting hole 26.

[0032] When the valve stem 27 is pressed down by the corresponding push rod 8, it will move downward in the valve cavity 23 so that the annular groove 28 aligns with the first connecting hole 25 and the second connecting hole 26. At this time, the first connecting hole 25 and the second connecting hole 26 will be connected through the annular groove 28 so that the first flow channel 18 is connected with the second flow channel 30, so as to realize the delivery of liquid under the action of the air pump.

[0033] Specific combination Figure 5 , Figure 7 and Figure 8In one embodiment of this utility model, the microchannel includes a plurality of fifth channels 36, sixth channels 40, ninth channels 46, eleventh channels 52 and fourteenth channels 57 disposed on the top of the microfluidic chip 11, and a plurality of fourth channels 34, seventh channels 42, tenth channels 48 and twelfth channels 54 disposed on the bottom of the microfluidic chip 11, and a plurality of third through holes 33, fifth through holes 35 and sixth through holes 36 and 47 disposed on the microfluidic chip 11. 7. Seventh through hole 39, eighth through hole 41, ninth through hole 43, tenth through hole 45, eleventh through hole 47, twelfth through hole 49, thirteenth through hole 51, fourteenth through hole 53, and fifteenth through hole 55; the two ends of the fourth flow channel 34 are connected to the corresponding third through hole 33 and fifth through hole 35; the two ends of the fifth flow channel 36 are connected to the corresponding fifth through hole 35 and sixth through hole 37; the two ends of the sixth flow channel 40 are connected to the corresponding seventh through hole 39 and eighth through hole 55. Hole 41 is connected. The two ends of the seventh flow channel 42 are connected to the corresponding eighth through hole 41 and ninth through hole 43. The two ends of the ninth flow channel 46 are connected to the corresponding tenth through hole 45 and eleventh through hole 47. The two ends of the tenth flow channel 48 are connected to the corresponding eleventh through hole 47 and twelfth through hole 49. The twelfth through hole 49 is connected to the corresponding waste liquid tank 50. The two ends of the eleventh flow channel 52 are connected to the corresponding thirteenth through hole 51 and fourteenth through hole 53. The two ends of the twelfth flow channel 54 are connected to the corresponding fourteenth through hole 53 and fifteenth through hole 55. The fifteenth through hole 55 and the second connecting seat 58 are both connected to the corresponding fourteenth flow channel 57. The sixth through hole 37, the seventh through hole 39, the tenth through hole 45 and the thirteenth through hole 51 are all connected to the corresponding first connecting seat 38. A conduit 68 is installed in both the tenth through hole 45 and the thirteenth through hole 51. The conduit 68 is located in the corresponding first PCR tube 69.

[0034] Furthermore, the top of the microfluidic chip 11 is provided with a third flow channel 32, an eighth flow channel 44, a thirteenth flow channel 56, and a fifteenth flow channel 64. The microfluidic chip 11 has a first connecting hole 63, a second connecting hole 65, a third connecting hole 66, and a fourth connecting hole 67. The first connecting hole 63 and each of the third through holes 33 communicate with the third flow channel 32. The second connecting hole 65 and each of the waste liquid tanks 50 communicate with the fifteenth flow channel 64. The third connecting hole 66 and each of the ninth through holes 43 communicate with the eighth flow channel 44. The fourth connecting hole 67 and each of the fourteenth flow channels 57 are connected to the thirteenth flow channel 56. The suction end of the first air pump 59 is connected to the first connecting hole 63 through a hose. The suction end of the second air pump 60 is connected to the second connecting hole 65 through a hose. The suction end of the third air pump 61 is connected to the third connecting hole 66 through a hose. The suction end of the fourth air pump 62 is connected to the fourth connecting hole 67 through a hose. One-way valves are installed at the third through hole 33, the ninth through hole 43, the twelfth through hole 49 and the fifteenth through hole 55.

[0035] When the first air pump 59 is started, the liquid in the first liquid storage tank 12 to the fifth liquid storage tank 16 can be input into the third liquid channel 32 through the first through hole 17, the first flow channel 18, the second flow channel 30 and the second through hole 31 when the valve mechanism 19 is in the open state.

[0036] When the third air pump 61 is activated, the gas in each of the first PCR tubes 69 can be extracted through the eighth flow channel 44, the ninth through hole 43, the seventh flow channel 42, the eighth through hole 41, the sixth flow channel 40, and the seventh through hole 39. The negative pressure formed in the first PCR tube 69 is used to draw the liquid in the third flow channel 32 into the first PCR tube 69 through the third through hole 33, the fourth flow channel 34, the fifth through hole 35, the fifth flow channel 36, and the sixth through hole 37, so as to mix with the substances in the first PCR tube 69.

[0037] By starting the second air pump 60, the gas in each waste liquid tank 50 can be extracted through the second connection hole 65 and the fifteenth flow channel 64. Then, the liquid in the first PCR tube 69 can be drawn into the corresponding waste liquid tank 50 by using negative pressure through the twelfth through hole 49, the tenth flow channel 48, the eleventh through hole 47, the ninth flow channel 46, the tenth through hole 45 and the corresponding conduit 68.

[0038] Activating the fourth air pump 62 will extract the gas from each of the second connectors 58 through the fourth connecting hole 67 and the thirteenth flow channel 56, so that the liquid in the first PCR tube 69 can be drawn into the corresponding second PCR tube 70 through the second connector 58, the fifteenth through hole 55, the twelfth flow channel 54, the fourteenth through hole 53, the eleventh flow channel 52, the thirteenth through hole 51 and the corresponding conduit 68.

[0039] Although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present invention should be included within the protection scope of the present invention.

Claims

1. A parallel distributed microfluidic channel device, characterized by: The system includes a base (1), on which a housing (10) is slidably mounted. A microfluidic chip (11) is fixedly mounted on the top of the housing (10), and a second linear drive mechanism (9) for driving the housing (10) is mounted on the base (1). A frame (2) is fixedly mounted on the top of the base (1), and a trapezoidal block (4) is connected to the frame (2) via a first linear drive mechanism (3). The microfluidic chip (11) passes through the inside of the frame (2), and five valve mechanisms (19) are provided on the microfluidic chip (11). Five transmission mechanisms are provided on the frame (2) at the moving path of the trapezoidal block (4), and the transmission mechanisms correspond one-to-one with the valve mechanism (19). The top surface of the microfluidic chip (11) is provided with a first liquid storage tank (12), a second liquid storage tank (13), a third liquid storage tank (14), a fourth liquid storage tank (15), and a fifth liquid storage tank (16). The microfluidic chip (11) is provided with several microchannels. The bottom of the microfluidic chip (11) is provided with a second flow channel (30) and five first flow channels (18). The liquid inlet end of the valve mechanism (19) corresponds to the valve mechanism (19). The first flow channel (18) is connected, and the liquid outlet end of the valve mechanism (19) is connected to the second flow channel (30). The inner bottom of the first liquid storage tank (12), the second liquid storage tank (13), the third liquid storage tank (14), the fourth liquid storage tank (15) and the fifth liquid storage tank (16) are all provided with a first through hole (17), and the bottom end of the first through hole (17) is connected to the corresponding first flow channel (18). Several micro-tubes are connected to the second flow channel (30). Several first connectors (38), waste liquid tanks (50) and second connectors are provided on the microfluidic chip (11). The first connector (38), the waste liquid tank (50), and the second connector (58) are connected to the corresponding flow channels. The first connector (38) is equipped with a first PCR tube (69), and the second connector (58) is equipped with a second PCR tube (70). The housing (10) is equipped with a first air pump (59), a second air pump (60), a third air pump (61), and a fourth air pump (62). The first air pump (59), the second air pump (60), the third air pump (61), and the fourth air pump (62) are all connected to the micro-tubes.

2. The parallel distributed microfluidic channel device of claim 1, wherein: The transmission mechanism includes a guide rod (5) that can slide through and be installed on the frame (2). The outer wall of the guide rod (5) inside the frame (2) is fitted with a first spring (7). The top end of the guide rod (5) is fixedly connected to a force-bearing block (6), and the bottom end of the guide rod (5) is fixedly connected to a top rod (8).

3. The parallel distributed microfluidic channel device of claim 2, wherein: The valve mechanism (19) includes a valve seat (20) fixedly embedded in the bottom of the microfluidic chip (11). The top of the valve seat (20) has a valve cavity (23), and the bottom of the valve seat (20) has a vent hole (24) communicating with the valve cavity (23). A valve stem (27) is slidably mounted on the microfluidic chip (11) at the corresponding position of each valve cavity (23). A second spring (29) is sleeved on the outer wall of the valve stem (27), and the lower end of the valve stem (27) is slidably mounted in the corresponding valve cavity (23). An annular groove (28) is provided on the outer wall of the valve cavity (23). The outer walls on both sides of the valve seat (20) are respectively provided with a first connecting hole (25) and a second connecting hole (26) that communicate with the valve cavity (23). The bottom of the microfluidic chip (11) and the corresponding positions of each valve seat (20) are provided with a first groove (21) and a second groove (22). The first groove (21) communicates with the corresponding first flow channel (18) and the first connecting hole (25). The second groove (22) communicates with the second flow channel (30) and the corresponding second connecting hole (26).

4. The parallel distributed microfluidic channel device of claim 1, wherein: The microchannels include several fifth channels (36), sixth channels (40), ninth channels (46), eleventh channels (52), and fourteenth channels (57) disposed on the top of the microfluidic chip (11). Several fourth channels (34), seventh channels (42), tenth channels (48), and twelfth channels (54) are provided on the bottom of the microfluidic chip (11). Several third through holes (33), fifth through holes (35), sixth through holes (37), seventh through holes (39), and twelfth through holes (54) are provided on the microfluidic chip (11). The fourth flow channel (34) has eight through holes (41), nine through holes (43), tenth through holes (45), eleventh through holes (47), twelfth through holes (49), thirteenth through holes (51), fourteenth through holes (53), and fifteenth through holes (55). The two ends of the fourth flow channel (34) are connected to the corresponding third through holes (33) and fifth through holes (35). The two ends of the fifth flow channel (36) are connected to the corresponding fifth through holes (35) and sixth through holes (37). The two ends of the sixth flow channel (40) are connected to the corresponding seventh through holes (39) and eighth through holes (41). The seventh flow channel (42) is connected at both ends to the corresponding eighth through hole (41) and ninth through hole (43). The ninth flow channel (46) is connected at both ends to the corresponding tenth through hole (45) and eleventh through hole (47). The tenth flow channel (48) is connected at both ends to the corresponding eleventh through hole (47) and twelfth through hole (49). The twelfth through hole (49) is connected to the corresponding waste liquid tank (50). The eleventh flow channel (52) is connected at both ends to the corresponding thirteenth through hole (51) and fourteenth through hole (53). The two ends of the two channels (54) are connected to the corresponding fourteenth through hole (53) and fifteenth through hole (55). The fifteenth through hole (55) and the second connector (58) are both connected to the corresponding fourteenth channel (57). The sixth through hole (37), seventh through hole (39), tenth through hole (45) and thirteenth through hole (51) are all connected to the corresponding first connector (38). The tenth through hole (45) and the thirteenth through hole (51) are each equipped with a catheter (68). The catheter (68) is located in the corresponding first PCR tube (69).

5. The parallel distributed microfluidic pipeline device of claim 4, wherein: The microfluidic chip (11) has a third flow channel (32), an eighth flow channel (44), a thirteenth flow channel (56), and a fifteenth flow channel (64) on its top. The microfluidic chip (11) has a first connection hole (63), a second connection hole (65), a third connection hole (66), and a fourth connection hole (67). The first connection hole (63) and each of the third through holes (33) are connected to the third flow channel (32). The second connection hole (65) and each of the waste liquid tanks (50) are connected to the fifteenth flow channel (64). The third connection hole (66) and each of the ninth through holes (43) are connected to the eighth flow channel (44). The fourth connecting hole (67) and each of the fourteenth flow channels (57) are connected to the thirteenth flow channel (56). The suction end of the first air pump (59) is connected to the first connecting hole (63) through a hose. The suction end of the second air pump (60) is connected to the second connecting hole (65) through a hose. The suction end of the third air pump (61) is connected to the third connecting hole (66) through a hose. The suction end of the fourth air pump (62) is connected to the fourth connecting hole (67) through a hose. One-way valves are installed at the third through hole (33), the ninth through hole (43), the twelfth through hole (49) and the fifteenth through hole (55).

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