Liftable temperature sensor structure and swing type bioreactor

Abstract

The utility model discloses a temperature sensor structure capable of rising and falling. The temperature sensor structure comprises a temperature sensor, a sensor fixing seat, a first shifting fork and a second shifting fork, the first shifting fork and the second shifting fork are arranged in parallel, one end of the first shifting fork and one end of the second shifting fork are rotationally connected with a shell of the temperature sensor through the sensor fixing base, and the other end of the first shifting fork and the other end of the second shifting fork are rotationally connected with an equipment base. And two connecting points of the two shifting forks and the equipment base and two connecting points of the two shifting forks and the sensor fixing seat are connected to form a parallelogram. According to the liftable temperature sensor structure and the swing type bioreactor provided by the utility model, the defects in the prior art are overcome, the temperature sensor can be flexibly lifted, the lifting direction is kept vertical, and the sensing end of the temperature sensor can be completely attached to a biological reaction bag on the tray, so that the accuracy of temperature detection is ensured.

Description

Technical Field

[0001] This utility model relates to the field of biopharmaceutical technology, and in particular to a temperature sensor structure that can be raised and lowered and a swing-type bioreactor. Background Technology

[0002] A temperature sensor is a sensor that senses temperature and converts it into a usable output signal. It is mainly divided into contact temperature sensors and resistance temperature sensors (RTS sensors): including platinum RTDs and copper RTDs. Platinum RTDs have high accuracy and good stability, and are often used for high-precision temperature measurement and control; copper RTDs are low-cost and highly sensitive, suitable for applications where measurement accuracy requirements are not particularly high and the temperature range is relatively low. Thermocouple temperature sensors: such as type K thermocouples and type S thermocouples. Type K thermocouples have high sensitivity, good linearity, and are inexpensive, and are widely used; type S thermocouples have high accuracy, good stability, and high temperature resistance, and are often used for high-temperature measurement and calibration.

[0003] Non-contact temperature sensors, including infrared temperature sensors: such as thermopile type and photonic type. Thermopile type infrared temperature sensors have a slower response speed but are low in cost and have good stability; photonic type infrared temperature sensors have a fast response speed and high sensitivity, and can be used for rapid temperature measurement and high-temperature measurement. Fiber optic temperature sensors: These utilize the relationship between the light transmission characteristics of optical fibers and temperature to measure temperature. For example, temperature sensors based on fiber optic gratings have advantages such as resistance to electromagnetic interference, corrosion resistance, and distributed measurement capabilities, making them suitable for temperature monitoring in harsh environments and large structures.

[0004] The existing temperature sensor design of the swing bioreactor has a fixed position and cannot be raised or lowered. Furthermore, due to the installation structure of the temperature sensor, the tray structure of the swing bioreactor cannot be flexibly disassembled. Therefore, to address the above problems, a height-adjustable temperature sensor structure and a swing bioreactor are proposed. Utility Model Content

[0005] The purpose of this invention is to overcome the existing defects by providing a height-adjustable temperature sensor structure and a swing-type bioreactor, wherein the temperature sensor can be flexibly raised and lowered; and the bioreactor can be adapted to multiple models of trays.

[0006] To achieve the above objectives, this utility model provides the following technical solution: a height-adjustable temperature sensor structure, including a temperature sensor, a sensor mounting base, a first shift fork, and a second shift fork;

[0007] The first fork and the second fork are arranged in parallel, and one end of each of the first fork and the second fork is rotatably connected to the housing of the temperature sensor through the sensor mounting base. The other end of each of the first fork and the second fork is rotatably connected to the device base. The two connection points of the two forks to the device base and the two connection points of the two forks to the sensor mounting base are connected by lines to form a parallelogram.

[0008] Preferably, the sensor mounting base includes a horizontal plate and a vertical plate, the temperature sensor is fixedly connected to the horizontal plate, and one end of the first fork and the second fork are rotatably connected to the vertical plate of the sensor mounting base.

[0009] Preferably, the horizontal plate of the sensor mounting base has a waist hole, the lower end of the temperature sensor has an external thread, and the lower end of the temperature sensor passes through the waist hole and is connected to the sensor mounting base by two nuts.

[0010] Preferably, the sensor mounting base is an L-shaped or C-shaped structure with the opening facing downwards.

[0011] Preferably, the other end of the second shift fork is provided with a striker, the end of the second shift fork connected to the striker is provided with a threaded hole, the lower end of the striker is provided with an external thread, and the striker is threadedly connected to the second shift fork.

[0012] Accordingly, this utility model also provides a swing-type bioreactor, including a motor, a device base, a tray, and a temperature sensor structure that can be raised and lowered as described above.

[0013] The equipment base has a swing fulcrum, and the motor is connected to the equipment base to drive the equipment base to swing back and forth around the swing fulcrum.

[0014] The tray is mounted on the equipment base and is used to support the bioreactor bags;

[0015] The tray has a sensor receiving hole, and the temperature sensor of the liftable temperature sensor structure is located in the sensor receiving hole;

[0016] The two forks of the liftable temperature sensor structure have two connection points with the device base, and the positions of these two connection points are fixed.

[0017] When the two forks of the liftable temperature sensor structure are rotated, the top of the temperature sensor can extend out of the sensor receiving hole and contact the bioreactor bag above it.

[0018] Preferably, the equipment base includes a first limiting post and a second limiting post, and the positions of the first limiting post and the second limiting post are fixed;

[0019] The first fork has through holes at both ends, and the end away from the sensor mounting base is sleeved on the first limiting post of the device base through its end through hole; the second fork has a through hole in the middle, and is sleeved on the second limiting post of the device base through its middle through hole.

[0020] Preferably, a striker is provided at the other end of the second shift fork, and a pad is provided at the bottom of the tray, with the pad positioned opposite to the striker;

[0021] When the tray is mounted on the equipment base, the pad at the bottom of the tray contacts the striker and applies downward pressure to the striker.

[0022] Compared with the prior art, the beneficial effects of this utility model are as follows: This liftable temperature sensor structure and oscillating bioreactor, by setting two forks that are rotatably connected to the equipment base and the fixed seat of the temperature sensor, and connecting the two forks with the two connection points of the equipment base and the two connection points of the sensor fixed seat to form a parallelogram, ensures that the temperature sensor remains vertical during the lifting process, and its top sensing end can completely fit the bioreactor bag on the tray, thereby ensuring the accuracy of temperature sensing; the structure is simple and can flexibly lift the temperature sensor according to the usage requirements. At the same time, by utilizing this feature, multiple temperature sensor modules can be placed in one base, and with different designed trays, it can be adapted to different usage environments, so that one equipment base can be used with multiple trays. Attached Figure Description

[0023] The accompanying drawings are provided to further illustrate the present invention and form part of the specification. They are used together with the embodiments of the present invention to explain the present invention, but do not constitute a limitation thereof. In the drawings:

[0024] Figure 1 This is a schematic diagram of the structure of the adjustable temperature sensor of this utility model;

[0025] Figure 2 This is a schematic diagram illustrating the operating principle of the temperature sensor structure of this utility model;

[0026] Figure 3 This is a schematic diagram of the tray used for single-bag culture according to this utility model;

[0027] Figure 4 This is a schematic diagram of the tray used for double-bag culture according to this utility model.

[0028] In the diagram: 1. Temperature sensor; 2. Nut; 3. Sensor mounting base; 4. First shift fork; 5. Second shift fork; 6. Strike pin. Detailed Implementation

[0029] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0030] Please see Figure 1-2 A height-adjustable temperature sensor structure includes a temperature sensor 1, a sensor mounting base 3, a first fork 4, and a second fork 5. The first fork 4 and the second fork 5 are arranged in parallel, and one end of each of the first fork 4 and the second fork 5 is rotatably connected to the housing of the temperature sensor 1 through the sensor mounting base 3. The other end of each of the first fork 4 and the second fork 5 is rotatably connected to the equipment base. The two connection points of the two forks to the equipment base and the two connection points of the two forks to the sensor mounting base 3 are connected by lines to form a parallelogram.

[0031] Specifically, such as Figure 2 As shown, the two connection points of the two forks to the device base form one side CD of a parallelogram. The two connection points of the two forks to the sensor mounting base 3 form the other side AB of the parallelogram, where AB is the opposite side of CD.

[0032] Specifically, since the two connection points between the two forks and the base of the device are fixed, that is, the extension direction of side CD remains unchanged, when the second fork 5 is rotated by force, the opposite side AB of CD can only move along its original extension direction.

[0033] In this embodiment, the extension direction of side CD is vertical. Therefore, the temperature sensor 1, which is fixed to the opposite side AB of CD, can only move up and down in the vertical direction.

[0034] In this embodiment, the sensor mounting base 3 includes a horizontal plate and a vertical plate. The temperature sensor 1 is fixedly connected to the horizontal plate, and one end of the first fork 4 and the second fork 5 are rotatably connected to the vertical plate of the sensor mounting base 3. A waist hole is provided on the horizontal plate of the sensor mounting base 3, and an external thread is provided at the lower end of the temperature sensor 1. The lower end of the temperature sensor 1 passes through the waist hole and is connected to the sensor mounting base 3 by two nuts 2. Preferably, the sensor mounting base 3 is an L-shaped or C-shaped structure with the opening facing downwards.

[0035] In another embodiment, the sensor mounting base 3 can also be the housing of the temperature sensor 1, as long as the housing has a vertical surface connected to the two forks, and the four connection points of the two forks can form a parallelogram.

[0036] Specifically, the other end of the second fork 5 is provided with a striker 6. The end of the second fork 5 that connects to the striker 6 has a threaded hole, and the lower end of the striker 6 has an external thread. The striker 6 is threadedly connected to the second fork 5. The tray mounted on the equipment base is located above the striker 6 and applies downward pressure to the striker 6, causing the temperature sensor 1 to rise vertically.

[0037] In this embodiment, the second fork 5 is located below the first fork 4, and the striker 6 is mounted at point E of the second fork 5. The striker 6 applies a downward force to point E, causing the temperature sensor 1 to rise vertically. In another embodiment, the mounting positions of the first fork 4 and the second fork 5 can be interchanged, and the height of the striker 6 on the second fork 5 needs to be adjusted accordingly to match the height of the upper tray. Similarly, the striker 6 applies a downward force to point E of the second fork 5, causing the temperature sensor 1 to rise vertically as well.

[0038] Please see Figure 3 , 4 A swing-type bioreactor includes a motor, a base, a tray, and a height-adjustable temperature sensor structure. The base has a swing fulcrum, and the motor is connected to the base to drive the base to swing back and forth around the fulcrum. The tray is mounted on the base to support the bioreactor bag. The tray has a sensor receiving hole, and the temperature sensor 1 of the height-adjustable temperature sensor structure is located in the sensor receiving hole. The two forks of the height-adjustable temperature sensor structure have two connection points with the base, and the positions of these two connection points are fixed. When the two forks of the height-adjustable temperature sensor structure rotate, the top end (i.e., the sensing end) of the temperature sensor 1 can extend out of the sensor receiving hole and contact the bioreactor bag above it.

[0039] Specifically, temperature sensor 1 has a cylindrical sensor probe at one end (i.e., the sensing end) and an externally threaded stud at the other end for mounting and fixing. The stud is hollow in the middle to facilitate the passage of the sensor probe's signal line. The top of the probe has a thermally conductive layer made of a material with excellent thermal conductivity, which facilitates effective temperature measurement of the sample under test. The sides of the probe are completely wrapped with an insulating layer to reduce the influence of ambient temperature on the temperature sensor.

[0040] Specifically, a tray is placed on the equipment base to support the bioreactor bag. Both the equipment base and the tray have sensor receiving holes. Temperature sensor 1 is located in the sensor receiving hole and can move up and down. When temperature sensor 1 moves upward, its sensing end can extend out of the sensor receiving hole and contact the bioreactor bag above it to detect the temperature of the bioreactor bag.

[0041] Specifically, the equipment base includes a first limiting post and a second limiting post, the positions of which are fixed; the other ends of the two shift forks are respectively sleeved on the first limiting post and the second limiting post, thus the positions of the two shift forks and the two connection points of the equipment base are fixed.

[0042] Specifically, the first fork 4 has through holes at both ends, and the end away from the sensor mounting base 3 is sleeved on the first limiting post of the equipment base through its end through hole; the second fork 5 has a through hole in the middle, and is sleeved on the second limiting post of the equipment base through its middle through hole.

[0043] Specifically, the other end of the second fork 5 is provided with a striker 6, and the bottom of the tray is provided with a pad, which is positioned opposite to the striker 6. When the tray is installed on the equipment base, the pad at the bottom of the tray contacts the striker 6 and applies downward pressure to the striker 6.

[0044] like Figure 1 and Figure 2 As shown, temperature sensor 1 is mounted on one side (horizontal side) of L-shaped mounting base 3. The other side (vertical side) of L-shaped mounting base 3 is provided with a first fork 4 and a second fork 5. One end A of the first fork 4 is rotatably connected to L-shaped mounting base 3, and the other end C has a first connecting hole, which is fitted onto a first limiting post (not shown in the figure). One end B of the second fork 5 is rotatably connected to L-shaped mounting base 3, and the other end E is fixedly connected to a striking pin 6. A second connecting hole is located at the middle position D of the second fork 5, which is fitted onto a second limiting post (not shown in the figure). Both the first and second limiting posts are fixed to the equipment base (not shown in the figure).

[0045] Specifically, the parallelogram fixing structure between the sensor mounting base 3, the first fork 4, and the second fork 5 is fully utilized, such as... Figure 2 C and D are the mounting points of the temperature sensor structure on the equipment base. By utilizing the properties of the parallelogram ABCD, and ensuring that the mounting holes of the temperature sensor are perpendicular to the tray plane (CD is perpendicular to the tray plane), the perpendicularity of AB to the tray plane can be achieved.

[0046] In practical use, the equipment base and the tray cooperate with each other, and the tray applies a downward force to the striking pin 6. When the striking pin 6 is subjected to a downward force, Figure 2Point E experiences a downward force. Since C and D are fixed points, this causes segment AB to move upward. Because ABCD is a parallelogram, and CD is perpendicular to the tray plane and is a fixed point, AC will rotate relative to point C, and BD will rotate relative to point D. This causes segment AB to rise vertically relative to the tray plane, further achieving the flexible lifting and lowering of temperature sensor 1. As the tray swings back and forth with the equipment base, since CD is perpendicular to the tray plane and its position is fixed, the lifting and lowering direction of temperature sensor 1 is always perpendicular to the tray plane, ensuring that the sensing end at the top of temperature sensor 1 remains in contact with the bioreactor bag on the tray.

[0047] Specifically, by utilizing this feature, multiple temperature sensor modules can be arranged on a single equipment base, and with different designed trays, they can be adapted to different usage environments, achieving the goal of one equipment base being compatible with multiple trays.

[0048] Specifically, in the single temperature sensor structure, during use, the tray is mounted on the equipment base. A downward force is applied to the striker 6 via a protrusion on the bottom of the tray, causing... Figure 2 Point E experiences a downward force. Since point CD is a fixed point and ABCD is a parallelogram, this causes AB to rise vertically. Figure 1 In the middle, the protrusion at the bottom of the tray applies a downward force to the striker 6, causing the sensor mounting base 3 to rise vertically to the tray, thereby causing the temperature sensor 1 mounted on the sensor mounting base 3 to rise vertically to the tray.

[0049] Specifically, in practical use, a swing bioreactor typically includes one or more temperature sensor structures, such as... Figure 3 As shown, when the base is used with a single-bag culture tray a, the raised pad a1 at the bottom of the single-bag culture tray a applies a downward force to the striker of the temperature sensor structure b in the middle, causing the temperature sensor structure to move upward through the opening of the single-bag culture tray a, thus allowing temperature detection of a single culture bag. Figure 4 As shown, when using the double-bag culture tray C, there are two raised pads C1 at the bottom of the double-bag culture tray C, which apply a downward force to the strikers of the temperature sensor structures b on both sides, causing the temperature sensor structures to move upward and through the two openings of the double-bag culture tray b, thereby allowing the two culture bags to perform temperature detection.

[0050] Specifically, when multiple temperature sensor structures exist, this structure, in conjunction with the corresponding tray, can be used to detect the temperature of multiple culture bags.

[0051] Finally, it should be noted that the above are merely preferred embodiments of this utility model and are not intended to limit the utility model. Although the utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this utility model should be included within the protection scope of this utility model.

Claims

1. A temperature sensor structure that can be raised, characterized by, Includes a temperature sensor (1), a sensor mounting base (3), a first shift fork (4), and a second shift fork (5); The first fork (4) and the second fork (5) are arranged in parallel, and one end of the first fork (4) and the second fork (5) are rotatably connected to the housing of the temperature sensor (1) through the sensor mounting base (3). The other end of the first fork (4) and the second fork (5) are rotatably connected to the equipment base. The two connection points of the two forks to the equipment base and the two connection points of the two forks to the sensor mounting base (3) are connected to form a parallelogram.

2. The temperature sensor structure according to claim 1, wherein The sensor mounting base (3) includes a horizontal plate and a vertical plate. The temperature sensor (1) is fixedly connected to the horizontal plate. One end of the first fork (4) and the second fork (5) is rotatably connected to the vertical plate of the sensor mounting base (3).

3. The temperature sensor structure according to claim 2, wherein The sensor mounting base (3) has a waist hole on its horizontal plate. The lower end of the temperature sensor (1) has an external thread. The lower end of the temperature sensor (1) passes through the waist hole and is connected to the sensor mounting base (3) by two nuts (2).

4. The temperature sensor structure according to claim 2, wherein The sensor mounting base (3) is an L-shaped or C-shaped structure with the opening facing downwards.

5. The temperature sensor structure according to claim 1, wherein The other end of the second shift fork (5) is provided with a striker (6). The end of the second shift fork (5) connected to the striker (6) is provided with a threaded hole. The lower end of the striker (6) is provided with an external thread. The striker (6) is threadedly connected to the second shift fork (5).

6. A rocking bioreactor characterized in that, Includes a motor, a device base, a tray, and a liftable temperature sensor structure as described in any one of claims 1 to 5; The equipment base has a swing fulcrum, and the motor is connected to the equipment base to drive the equipment base to swing back and forth around the swing fulcrum. The tray is mounted on the equipment base and is used to support the bioreactor bags; The tray has a sensor receiving hole, and the temperature sensor (1) of the adjustable temperature sensor structure is located in the sensor receiving hole; The two forks of the liftable temperature sensor structure have two connection points with the device base, and the positions of these two connection points are fixed. When the two forks of the liftable temperature sensor structure are rotated, the top of the temperature sensor (1) can extend out of the sensor receiving hole and contact the bioreactor bag above it.

7. The rocking bioreactor of claim 6, wherein, The equipment base includes a first limiting post and a second limiting post, and the positions of the first limiting post and the second limiting post are fixed. The first fork (4) has through holes at both ends, and the end away from the sensor mounting base (3) is sleeved on the first limiting post of the equipment base through its end through hole; the second fork (5) has a through hole in the middle, and is sleeved on the second limiting post of the equipment base through its middle through hole.

8. The rocking bioreactor of claim 6, wherein, The other end of the second fork (5) is provided with a striker (6), and the bottom of the tray is provided with a pad, which is positioned opposite to the striker (6); When the tray is mounted on the device base, the pads of the tray bottom come into contact with the striker (6) and exert a downward pressure on the striker (6).

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