Rotary sterilization device for plastic ampoules

Abstract

A rotary sterilization device for plastic ampoules comprises a water bath type sterilizer and a sterilization vehicle for placing the plastic ampoules, a rotating body matched with the sterilization vehicle is rotatably mounted in the water bath type sterilizer, and a driving device for driving the rotating body to drive the sterilization vehicle to rotate is mounted on the water bath type sterilizer. The driving equipment is in transmission connection with the rotating body, a stuffing box seal is arranged at the joint of the driving equipment and the water bath type sterilizer, the rotating body is transversely arranged, and a supporting roller for carrying out rotary supporting fit on the rotating body is also arranged in the water bath type sterilizer; a heating pipeline, a cleaning pipeline and a vacuumizing pipeline are fixedly communicated with the water bath type sterilizer, the heating pipeline is externally connected with a superheated water pipeline, the cleaning pipeline is externally connected with a clean water pipeline, and a vacuum pump is mounted on the vacuumizing pipeline. The utility model integrates the functions of sterilization, leak detection and cleaning, and has the advantages of uniform sterilization temperature, fast heat exchange and high sterilization efficiency.

Description

Technical Field

[0001] This utility model relates to the field of pharmaceutical sterilization technology, and in particular to a rotary sterilization device for plastic ampoules. Background Technology

[0002] Ampoules are currently the most common packaging form for small-volume aqueous injections in clinical practice. Glass is the most common material. However, in recent years, glass ampoules have presented several challenges, including difficulty in opening them by hand, the risk of finger cuts, easy wear and tear on the drug labeling, and the potential for adverse events such as infusion reactions caused by glass shards. Plastic ampoules, on the other hand, are easy to open and do not cause cuts or other adverse events. Therefore, plastic ampoules are increasingly being used clinically. Plastic ampoules offer the following advantages: clear labeling for easier identification; easier storage; convenient use and no risk of injury to operators; less prone to breakage, easy to carry and transport; and prevention of foreign matter contamination during opening.

[0003] However, the sterilization process for plastic ampoules needs to meet more stringent standards: traditional moist heat sterilization may cause plastic deformation or aging, affecting drug quality; while radiation sterilization can avoid high temperatures, it may have a potential impact on the stability of the drug solution; in addition, plastic materials have poor thermal conductivity, and it is necessary to ensure that the sterilization medium is in full contact during the sterilization process to avoid local residual microorganisms. Utility Model Content

[0004] The technical problem to be solved by this utility model is to address the shortcomings of the existing technology by providing a rotary sterilization device for plastic ampoules that integrates sterilization, leak detection, and cleaning functions, with uniform sterilization temperature, fast heat exchange, and high sterilization efficiency.

[0005] The technical problem to be solved by this utility model is achieved through the following technical solution. This utility model is a rotary sterilization device for plastic ampoules, comprising a water bath sterilizer and a sterilization cart for holding the plastic ampoules. A rotating body that cooperates with the sterilization cart is rotatably installed inside the water bath sterilizer. A drive device for driving the rotating body to rotate the sterilization cart is installed on the water bath sterilizer. The drive device is connected to the rotating body via a transmission connection. A stuffing box seal is installed at the junction of the drive device and the water bath sterilizer. The rotating body is arranged laterally. Support rollers for supporting the rotation of the rotating body are also installed inside the water bath sterilizer. A heating pipe, a cleaning pipe, and a vacuum pipe are fixedly connected to the water bath sterilizer. A superheated water pipe is connected to the heating pipe, a clean water pipe is connected to the cleaning pipe, and a vacuum pump is installed on the vacuum pipe.

[0006] The technical problem to be solved by this utility model can also be further achieved through the following technical solution: For the above-mentioned plastic ampoule rotary sterilization device, an opening is provided on the water bath sterilizer at the junction of the drive device and the water bath sterilizer, and a stuffing box seal is installed on the water bath sterilizer at the opening. The drive end of the drive device extends into the stuffing box seal from the outside to the inside and is connected to the rotating body through a transmission gear.

[0007] The technical problem to be solved by this utility model can also be further achieved through the following technical solution: For the above-mentioned plastic ampoule rotary sterilization device, the driving device is a geared motor, and meshing transmission gears are installed on the motor shaft and the outer side of the rotating body of the geared motor.

[0008] The technical problem to be solved by this utility model can also be further achieved by the following technical solution: For the above-mentioned plastic ampoule rotary sterilization device, the support rollers are provided in two sets, and the two sets of support rollers are respectively provided on the water bath sterilizers on both sides below the rotating body, and each set of support rollers is provided with at least 2 support rollers.

[0009] The technical problem to be solved by this utility model can also be further achieved through the following technical solution: For the above-mentioned plastic ampoule rotary sterilization device, the superheated water pipe is connected to a plate heat exchanger, the hot inlet of the plate heat exchanger is connected to the boiler steam pipe, the cold inlet of the plate heat exchanger is connected to the clean water pipe, and the superheated water pipe is connected to the cold outlet of the plate heat exchanger.

[0010] The technical problem to be solved by this utility model can also be further achieved through the following technical solution: For the above-mentioned plastic ampoule rotary sterilization device, a heating nozzle and a cleaning nozzle are installed in the water bath sterilizer. The heating nozzle is connected to the heating pipe, and the cleaning nozzle is connected to the cleaning pipe.

[0011] The technical problem to be solved by this utility model can also be further achieved through the following technical solution: For the above-mentioned plastic ampoule rotary sterilization device, the water bath sterilizer and the rotating body are both cylindrical, and the sterilization cart is rectangular.

[0012] Compared with existing technologies, this utility model provides a sterilization device for plastic ampoules that integrates sterilization, leak detection, and cleaning functions. This device uses moist heat steam sterilization. To prevent contamination of the sterilized items, it does not use boiler steam for direct sterilization. Instead, boiler steam heats the internally circulating clean water in a plate heat exchanger. The clean internally circulating water becomes superheated water under the high-temperature boiler steam, and then becomes superheated, pure, supersaturated steam under depressurized conditions in the water bath sterilizer to sterilize the plastic ampoules. The rotating body's rotational function keeps the plastic ampoules constantly agitated, preventing sedimentation, ensuring uniform sterilization temperature, rapid heat exchange, and high sterilization efficiency. After the sterilization cycle is complete, a vacuum is used for leak detection when the sterilization cart rotates to 45°, 90°, 135°, and 180°. Afterward, the sterilization cart is cleaned, rotated to control water flow, cooled, and then the door is opened before removal and closing. Attached Figure Description

[0013] Figure 1 This is a schematic diagram of the structure of this utility model;

[0014] Figure 2 This is a schematic diagram of the installation structure of the sterilization cart of this utility model. Detailed Implementation

[0015] To make the objectives, technical solutions, and advantages of the embodiments of this utility model clearer, the technical solutions of the embodiments of this utility model will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this utility model, not all embodiments. Based on the embodiments of this utility model, all other embodiments obtained by those skilled in the art without creative effort are within the protection scope of this utility model.

[0016] Reference Figure 1-2 A rotary sterilization device for plastic ampoules includes a water bath sterilizer 1 and a sterilization cart 3 for holding plastic ampoules 6. A rotating body 2, which cooperates with the sterilization cart 3, is rotatably installed inside the water bath sterilizer 1. The water bath sterilizer 1 is the main structure of the entire device and is cylindrical in shape, providing a closed and stable environment for the sterilization process. Its internal space is spacious enough to accommodate the rotating body 2 and the sterilization cart 3, and ensures sufficient space for various operations during the sterilization process. Preferably, a heating pipe, a cleaning pipe, and a vacuum pipe are fixedly connected to the water bath sterilizer 1, which respectively undertake the important functions of heating, cleaning, and vacuuming. The heating pipe is connected to a superheated water pipe, the cleaning pipe is connected to a clean water pipe, and a vacuum pump is installed on the vacuum pipe.

[0017] The rotating body 2 is horizontally arranged inside the water bath sterilizer 1. It is also cylindrical in shape and matches the shape of the water bath sterilizer 1, which facilitates its rotation inside. The rotating body 2 cooperates with the sterilization cart 3 to fix and drive the sterilization cart 3 to rotate. In order to realize the rotational installation of the rotating body 2, support rollers 7 are also installed inside the water bath sterilizer 1 to support the rotation of the rotating body 2. Preferably, there are two sets of support rollers 7, and the two sets of support rollers 7 are respectively arranged on the water bath sterilizer 1 on both sides below the rotating body 2. Each set of support rollers 7 has at least 2 support rollers 7.

[0018] The sterilization cart 3 is rectangular in shape and is specifically designed to hold plastic ampoules 6. It can easily enter and leave the sterilizer via the automatic feeding and discharging system of the water bath sterilizer 1. During the sterilization process, the sterilization cart 3 is loaded in the rotating body 2. The fixing effect of the rotating body 2 ensures that the plastic ampoules 6 will not shift or be damaged during the rotation.

[0019] To provide power for the rotation of the rotating body 2, a drive device 4 is installed on the water bath sterilizer 1 to drive the rotating body 2 and the sterilization cart 3 to rotate. The drive device 4 is connected to the rotating body 2. A stuffing box seal 5 is installed at the junction of the drive device 4 and the water bath sterilizer 1. Specifically, an opening is provided on the water bath sterilizer 1 at the junction of the drive device 4 and the water bath sterilizer 1. The stuffing box seal 5 is installed on the water bath sterilizer 1 at the opening. The drive end of the drive device 4 extends into the stuffing box seal 5 from the outside to the inside and is connected to the rotating body 2 through a transmission gear. The stuffing box seal 5 can effectively prevent liquid leakage inside the water bath sterilizer 1 and ensure the normal operation of the equipment. Preferably, the drive device 4 is a geared motor, and meshing transmission gears are installed on the motor shaft of the geared motor and the outside of the rotating body 2.

[0020] In actual use, the superheated water pipe is connected to a plate heat exchanger. The hot end inlet of the plate heat exchanger is connected to the boiler steam pipe, the cold end inlet of the plate heat exchanger is connected to the clean water pipe, and the superheated water pipe is connected to the cold end outlet of the plate heat exchanger. During the sterilization process, boiler steam enters the hot end of the plate heat exchanger and heats the clean water in the cold end in a partitioned manner, so that the clean water is heated to become superheated water. Under the condition of depressurization in the water bath sterilizer 1, the superheated water will quickly vaporize into superheated pure supersaturated steam. This high temperature and high pressure supersaturated steam can fully penetrate into all parts of the plastic ampoule 6, effectively kill the microorganisms in it, and achieve a highly efficient sterilization effect.

[0021] During the leak detection process, the vacuum pump performs a vacuuming operation inside the water bath sterilizer 1 through the vacuuming pipeline. When a certain degree of vacuum is formed inside the sterilizer, if there is a leak in the plastic ampoule 6, the liquid in the plastic ampoule 6 will seep out due to the vacuum suction, reducing the amount of liquid in the plastic ampoule 6. This makes it easier to accurately determine whether there is a leak in the plastic ampoule 6 through subsequent testing (such as light inspection).

[0022] A heating nozzle and a cleaning nozzle are installed inside the water bath sterilizer 1. The heating nozzle is connected to the heating pipe, and the cleaning nozzle is connected to the cleaning pipe. This allows the heating nozzle to spray hot water onto the sterilization cart 3, and the cleaning nozzle to spray clean water onto the sterilization cart 3, ensuring that all parts of the plastic ampoule 6 are thoroughly cleaned and that any leaked liquid is removed during the leak detection process.

[0023] The usage process of this utility model is as follows:

[0024] The sterilization cart 3 enters the sterilizer 1 through the automatic feeding and discharging system and is loaded into the rotating body 2. The rotating body 2 fixes the sterilization cart 3 in place, and then the rotating body 2 is slowly rotated by the drive device 4. At this time, the plate heat exchanger starts to work, heating the clean water into superheated water. The superheated water forms superheated pure supersaturated steam in the water bath sterilizer 1, which sterilizes the plastic ampoules 6 in all directions. During the rotation, the steam can act evenly on all parts of the plastic ampoules 6 to ensure the consistency and thoroughness of the sterilization effect.

[0025] After sterilization, the rotating body 2 is controlled by the rotating device to stop at fixed positions of 45°, 90°, 135°, and 180°. The vacuum pump is then started to perform a vacuuming operation inside the sterilizer and to check for leaks in the plastic ampoules 6 in the sterilization cart 3.

[0026] After the leak detection is completed, the cleaning pipeline is turned on to deliver clean water to the cleaning nozzle to clean the plastic ampoules 6 inside the sterilization cart 3. The rotating body 2 continues to rotate during the cleaning process, so that the cleaning nozzle can fully cover the surface of the plastic ampoules 6 and thoroughly clean the medicine that leaked during the leak detection process.

[0027] After the cleaning cycle is completed, the rotating body 2 continues to rotate, using the centrifugal force generated by the rotation to remove excess water from the plastic ampoules 6 and the sterilization cart 3. Then, the drying cycle begins, where appropriate heating and ventilation measures are used to further remove moisture from the surface of the plastic ampoules 6, ensuring that they are dry.

[0028] After drying, a cooling process (such as natural cooling or ventilation cooling) is carried out to reduce the temperature of the plastic ampoule 6 to a suitable range. Finally, the rotating body 2 releases the lock on the sterilization cart 3, and the sterilization cart 3 discharges through the automatic feeding and discharging system of the water bath sterilizer 1, completing the entire sterilization, leak detection, cleaning and drying process.

Claims

1. A rotary sterilization device for plastic ampoules, characterized in that: The device includes a water bath sterilizer and a sterilization cart for holding plastic ampoules. A rotating body that rotates within the water bath sterilizer and works in conjunction with the sterilization cart is mounted on the water bath sterilizer. A drive device is installed on the water bath sterilizer to drive the rotating body and rotate the sterilization cart. The drive device is connected to the rotating body via a transmission connection. A stuffing box seal is installed at the junction of the drive device and the water bath sterilizer. The rotating body is arranged laterally. Support rollers for rotating and supporting the rotating body are also installed inside the water bath sterilizer. A heating pipe, a cleaning pipe, and a vacuum pipe are fixedly connected to the water bath sterilizer. The heating pipe is connected to an external superheated water pipe, the cleaning pipe is connected to an external clean water pipe, and a vacuum pump is installed on the vacuum pipe.

2. The rotary sterilization device for plastic ampoules according to claim 1, characterized in that: An opening is provided on the water bath sterilizer at the junction of the drive device and the water bath sterilizer. A stuffing box seal is installed on the water bath sterilizer at the opening. The drive end of the drive device extends into the stuffing box seal from the outside to the inside and is connected to the rotating body through a transmission gear.

3. The rotary sterilization device for plastic ampoules according to claim 1 or 2, characterized in that: The driving device is a geared motor, and meshing transmission gears are installed on the outside of the motor shaft and the rotating body of the geared motor.

4. The rotary sterilization device for plastic ampoules according to claim 1, characterized in that: The support rollers are provided in two sets, which are respectively set on the water bath sterilizers on both sides below the rotating body. Each set of support rollers is provided with at least 2 support rollers.

5. The rotary sterilization device for plastic ampoules according to claim 1, characterized in that: The superheated water pipe is connected to an external plate heat exchanger. The hot inlet of the plate heat exchanger is connected to the boiler steam pipe, the cold inlet of the plate heat exchanger is connected to the clean water pipe, and the superheated water pipe is connected to the cold outlet of the plate heat exchanger.

6. The rotary sterilization device for plastic ampoules according to claim 1, characterized in that: The water bath sterilizer is equipped with heating nozzles and cleaning nozzles. The heating nozzles are connected to the heating pipes, and the cleaning nozzles are connected to the cleaning pipes.

7. The rotary sterilization device for plastic ampoules according to claim 1, characterized in that: The water bath sterilizer and the rotating body are both cylindrical, while the sterilization cart is rectangular.

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