Cutting-free silica gel mold for soluble microneedle patch

Abstract

The utility model discloses a soluble microneedle patch cutting-free type silica gel mold which comprises a bottom mold, a lower mold, a microneedle hole and a limiting rod, the lower mold is arranged in the bottom mold, the microneedle hole is formed in the top of the lower mold, a top mold is arranged in the bottom mold, an inclined step is arranged on the top of the top mold, and the limiting rod is arranged on the bottom mold. Connecting blocks are arranged on the two sides of the top die, connecting shafts are arranged on one sides of the connecting blocks, the connecting shafts are rotationally connected with limiting blocks, limiting grooves are formed in the two sides of the bottom die, limiting rods are arranged in the limiting grooves, clamping grooves are formed in one sides of the limiting blocks, and the clamping grooves are matched with the limiting rods. After the patch base body is connected with the formed microneedle, the limiting rod is removed through the limiting block, and the top mold is pulled through the groove, so that demolding of the microneedle and the bottom mold is facilitated, the demolding efficiency and quality of the microneedle are improved, demolding convenience is improved, and damage to the microneedle during demolding is reduced.

Description

A soluble microneedle patch cut-free silicone mold Technical Field

[0001] This utility model relates to the field of silicone mold technology, specifically a soluble microneedle patch silicone mold that does not require cutting. Background Technology

[0002] Microneedle injection methods include direct injection and patch application. Microneedles on microneedle patches are generally soluble microneedles. Microneedles are a relatively new transdermal drug delivery device, typically consisting of a group of needle tips 25–2000 μm long arranged on a base. They achieve minimally invasive and painless drug delivery by piercing the stratum corneum of the skin. Microneedle technology has received increasing attention and has been widely used in cosmetic applications, especially in microcrystalline eye patches. Currently, the main microneedle mold materials include stainless steel, silicone, silicon wafers, and PDMS. Stainless steel, silicone, and PDMS have certain advantages in the preparation of microneedle patches due to their low adhesion to microneedle membranes and ease of separation.

[0003] A search revealed Chinese utility model patent CN215242325U, "A Cut-Free Silicone Mold for Soluble Microneedle Patches," which includes a silicone mold body in a cuboid shape. The upper surface of the mold body has recesses, and the bottom of each recess has an array of microneedle holes for forming microneedles. The recesses form the final irregular shape of the soluble microneedle patch. The periphery of the recesses is sloped, creating an open design. This application offers the following anticipated technical advantages: the sloped design facilitates the removal of the microneedle patch, and the produced microneedle patch does not require secondary cutting or a specially customized cutter, thus facilitating control over the production of the microneedle patch.

[0004] The existing device has the following problems when in use: the microneedles at the bottom of the microneedle patch are relatively fragile, while the silicone is very soft. This causes the silicone mold to deform under the force during demolding, which damages the microneedles at the bottom of the patch and increases the defect rate. Summary of the Invention

[0005] The purpose of this invention is to provide a soluble microneedle patch silicone mold that does not require cutting, so as to solve the problems mentioned in the background art.

[0006] To achieve the above objectives, this utility model provides the following technical solution: a soluble microneedle patch cut-free silicone mold, comprising a bottom mold, a lower mold, microneedle holes, and a limiting rod. The lower mold is disposed inside the bottom mold, and the microneedle holes are disposed on the top of the lower mold. A top mold is disposed inside the bottom mold, and an inclined step is disposed on the top of the top mold. Connecting blocks are disposed on both sides of the top mold, and a connecting shaft is disposed on one side of each connecting block. The connecting shaft is rotatably connected to the limiting block.

[0007] By adopting the above technical solution, the patch substrate is injected into the bottom mold through micro-needle holes and placed inside the top mold. After the patch substrate is connected with the formed micro-needles, the limiting rod is released by the limiting block, and the top mold is pulled by the groove to facilitate the demolding of the micro-needles from the bottom mold. The demolding effect of the patch substrate is improved by the inclined steps.

[0008] Preferably, the bottom mold has limit grooves on both sides, and limit rods are provided inside the limit grooves.

[0009] Preferably, a slot is provided on one side of the limiting block, and the slot is adapted to the limiting rod.

[0010] By adopting the above technical solution, when in use, the top mold is placed inside the bottom mold, and the top mold and bottom mold are installed by the limiting blocks on both sides of the top mold and the limiting rods on both sides of the bottom mold. This makes it easy to disassemble the top mold and bottom mold and improves the demolding efficiency of the patch.

[0011] Preferably, the top mold has a plurality of micro-pin holes inside, and grooves are provided on both sides of the top mold.

[0012] Preferably, a sealing ring is provided on the outer side of the lower mold, and the sealing ring is a square ring.

[0013] By adopting the above technical solution, the sealing performance of the connection between the top mold and the bottom mold is increased by using a sealing ring.

[0014] Preferably, the limiting rod, connecting block, connecting shaft, and limiting block are all made of PP material.

[0015] By adopting the above technical solutions, the rigidity of the limiting rod, connecting block, connecting shaft, and limiting block is strengthened, thereby improving the stability of the connection.

[0016] Compared with the prior art, the beneficial effects of this utility model are: after the patch substrate is connected to the formed microneedles, the limiting rod is released by the limiting block, and the top mold is pulled by the groove, which facilitates the demolding of the microneedles from the bottom mold, improves the efficiency and quality of microneedle demolding, increases the convenience of demolding, and reduces the damage to the microneedles during demolding. Attached Figure Description

[0017] Figure 1 is a schematic diagram of the overall structure of this utility model;

[0018] Figure 2 is a cross-sectional structural diagram of this utility model;

[0019] Figure 3 is a schematic diagram of the limiting groove structure of this utility model;

[0020] Figure 4 is a schematic diagram of the groove structure of this utility model.

[0021] In the diagram: 1. Bottom mold; 2. Top mold; 3. Inclined step; 4. Lower mold; 5. Sealing ring; 6. Micro-pin hole; 7. Connecting shaft; 8. Connecting block; 9. Limiting block; 10. Limiting groove; 11. Limiting rod; 12. Groove. Detailed Implementation

[0022] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0023] This utility model provides a technical solution: a soluble microneedle patch silicone mold that requires no cutting. Please refer to Figures 1, 2, 3, and 4. It includes a bottom mold 1, a lower mold 4, microneedle holes 6, and a limiting rod 11. The lower mold 4 is located inside the bottom mold 1, and the top of the lower mold 4 has microneedle holes 6. A top mold 2 is located inside the bottom mold 1, and the top mold 2 has several microneedle holes 6. The patch substrate is placed inside the top mold 2 by injecting material into the bottom mold 1 through the microneedle holes 6. The top of the top mold 2 has an inclined step 3 to improve the demolding effect of the patch substrate. Connecting blocks 8 are located on both sides of the top mold 2, and a connecting shaft 7 is located on one side of each connecting block 8. The connecting shaft 7 is rotatably connected to a limiting block 9. Limiting rods are also provided on both sides of the bottom mold 1. The groove 10 has a slot on one side of the limiting block 9, which is adapted to the limiting rod 11. The limiting groove 10 has a limiting rod 11 inside. In use, the top mold 2 is placed inside the bottom mold 1. The top mold 2 and the bottom mold 1 are installed by the limiting blocks 9 on both sides of the top mold 2 cooperating with the limiting rods 11 on both sides of the bottom mold 1. The limiting rod 11, connecting block 8, connecting shaft 7 and limiting block 9 are all made of PP material. After the patch substrate is connected to the formed micro needle, the limiting rod 11 is released by the limiting block 9. The top mold 2 has grooves 12 on both sides. The grooves 12 pull the top mold 2 to facilitate the demolding of the micro needle from the bottom mold 1. The outer side of the lower mold 4 is provided with a sealing ring 5. The sealing ring 5 is a square ring. The sealing ring 5 increases the sealing of the connection between the top mold 2 and the bottom mold 1.

[0024] Working principle: In use, the top mold 2 is placed inside the bottom mold 1. The top mold 2 and the bottom mold 1 are installed by the limiting blocks 9 on both sides of the top mold 2 and the limiting rods 11 on both sides of the bottom mold 1. The sealing ring 5 increases the sealing of the connection between the top mold 2 and the bottom mold 1. The patch substrate is placed inside the top mold 2 by injecting through the micro needle hole 6. After the patch substrate connects with the formed micro needle, the limiting rods 11 are released by the limiting blocks 9. The top mold 2 is pulled by the groove 12 to facilitate the demolding of the micro needle from the bottom mold 1. The inclined step 3 improves the demolding effect of the patch substrate.

[0025] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A soluble microneedle patch cut-free silicone mold, comprising a bottom mold (1), a lower mold (4), microneedle holes (6), and a limiting rod (11), characterized in that: The bottom mold (1) is provided with a lower mold (4) inside, and the top of the lower mold (4) is provided with micro-pin holes (6). The bottom mold (1) is provided with a top mold (2) inside, and the top of the top mold (2) is provided with an inclined step (3). Both sides of the top mold (2) are provided with connecting blocks (8), and one side of the connecting block (8) is provided with a connecting shaft (7). The connecting shaft (7) is rotatably connected to a limit block (9).

2. The dissolvable microneedle patch free-cutting silicone mold of claim 1, wherein: Limiting grooves (10) are provided on both sides of the bottom mold (1), and limiting rods (11) are provided inside the limiting grooves (10).

3. The soluble microneedle patch cut-free silicone mold according to claim 1, characterized in that: The limiting block (9) has a slot on one side, which is adapted to the limiting rod (11).

4. The dissolvable microneedle patch free-cutting silicone mold of claim 1, wherein: The top mold (2) has several micro-pin holes (6) inside, and grooves (12) are provided on both sides of the top mold (2).

5. The dissolvable microneedle patch free-cutting silicone mold of claim 1, wherein: A sealing ring (5) is provided on the outer side of the lower mold (4), and the sealing ring (5) is a square ring.

6. The soluble microneedle patch cut-free silicone mold according to claim 1, characterized in that: The limiting rod (11), connecting block (8), connecting shaft (7), and limiting block (9) are all made of PP material.

Images