Volume-controllable nucleic acid mass spectrum adsorption resin sample injector

Abstract

The utility model discloses a volume-controllable nucleic acid mass spectrum adsorbent resin sample injector, which relates to the technical field of sample injectors and comprises a shell, a suction unit is arranged at the lower end of the shell, a pull rod is connected to the upper end of the shell in a sliding manner, a hexagonal knob is fixedly connected to the upper end of the pull rod, and the hexagonal knob is fixedly connected to the lower end of the pull rod. A first spring is fixedly connected to the inner top wall of the shell and sleeves the outer side of the pull rod, a baffle is fixedly connected to the inner wall of the shell and located at the lower end of the first spring, and a digital display device is installed in the shell. Through unique design, the sample injector can accurately control the sampling amount of the adsorption resin, the pressing height is in direct proportion to the suction capacity, and an operator can flexibly set the suction amount according to experimental requirements. In addition, the sample injector also has the characteristics of stable structure, simplicity and convenience in operation, easiness in cleaning and replacement of parts, and can effectively reduce personal errors, improve experiment efficiency and repeatability and meet diversified experiment requirements.

Description

Technical Field

[0001] This utility model relates to the field of sample dispenser technology, and in particular to a nucleic acid mass spectrometry adsorption resin sample dispenser with controllable capacity. Background Technology

[0002] Nucleic acid mass spectrometry (NMS) has significant applications in gene detection, disease diagnosis, and drug development. As a key material for nucleic acid extraction and purification, NMS adsorption resins effectively remove impurity ions from samples, preventing interference peaks during mass spectrometry detection and ensuring the accuracy and sensitivity of analytical results. However, existing pipettes have several problems when handling NMS adsorption resins: firstly, they cannot precisely control the sample volume, leading to insufficient or excessive sample volume, affecting the accuracy of analytical results; secondly, pipettes are complex to operate and difficult to adjust, making them unsuitable for high-throughput sample processing and susceptible to human error, resulting in poor experimental repeatability. Utility Model Content

[0003] To address the shortcomings of existing technologies, this invention provides a capacity-controlled nucleic acid mass spectrometry adsorption resin pipette. Through its unique design, this pipette enables precise control of the sample volume taken from the adsorption resin; the pressing height is directly proportional to the absorption volume, allowing operators to flexibly set the absorption amount according to experimental needs. Furthermore, this pipette features stable structure, simple operation, and easy cleaning and replacement of parts, effectively reducing human error, improving experimental efficiency and repeatability, and meeting diverse experimental requirements.

[0004] This utility model also provides a nucleic acid mass spectrometry adsorption resin pipette with the above-mentioned capacity controllable, comprising: a shell, an aspiration unit provided at the lower end of the shell, a pull rod slidably connected to the upper end of the shell, a hexagonal knob fixedly connected to the upper end of the pull rod, a threaded rod fixedly connected to one end of the pull rod inside the shell, a spring fixedly connected to the inner top wall of the shell and sleeved on the outside of the pull rod, a baffle fixedly connected to the inner wall of the shell and located at the lower end of the spring, and a digital display device installed inside the shell;

[0005] The suction unit includes a suction tube fixedly connected to the lower end of the outer shell. The suction tube passes through the outer shell. A locking block is fixedly connected to the outer wall of one end of the suction tube inside the outer shell. A piston rod is slidably connected to the inner wall of the suction tube. A connecting rod is fixedly connected to one end of the piston rod. A spring is fixedly connected to the lower end of the connecting rod, located on the outer wall of the piston rod.

[0006] According to the aforementioned capacity-controllable nucleic acid mass spectrometry adsorption resin pipette, the end of the connecting rod away from the piston rod passes through the digital display device and is attached to the bottom end of the threaded rod.

[0007] According to the aforementioned capacity-controllable nucleic acid mass spectrometry adsorption resin pipette, a pipette tip is installed at the lower end of the aspiration tube, and the pipette tip is fitted onto the outer wall of the aspiration tube.

[0008] According to the aforementioned capacity-controllable nucleic acid mass spectrometry adsorption resin pipette, the outer wall of the outer shell is provided with a through hole, which is located on one side of the digital display device.

[0009] According to the aforementioned capacity-controllable nucleic acid mass spectrometry adsorption resin pipette, the outer wall of the outer shell is provided with an anti-slip pad, which is made of rubber material.

[0010] According to the aforementioned capacity-controllable nucleic acid mass spectrometry adsorption resin pipette, the threaded rod passes through the baffle and is threadedly connected to it.

[0011] Additional aspects and advantages of this invention will be set forth in part in the description which follows, and in part will be obvious from the description, or may be learned by practice of the invention. Attached Figure Description

[0012] The present invention will be further described below with reference to the accompanying drawings and embodiments;

[0013] Figure 1 This is a cross-sectional view of the outer shell of a capacity-controllable nucleic acid mass spectrometry adsorption resin pipette according to the present invention.

[0014] Figure 2 for Figure 1 Enlarged view of the structure at point A in the middle;

[0015] Figure 3 This is a three-dimensional structural diagram from a side view of the nucleic acid mass spectrometry adsorption resin pipette of the present invention;

[0016] Figure 4 This is a diagram showing the internal structure of a capacity-controlled nucleic acid mass spectrometry adsorption resin pipette according to this invention.

[0017] Legend:

[0018] 1. Outer shell; 2. Suction unit; 3. Pull rod; 4. Hexagonal knob; 5. Threaded rod; 6. Spring 1; 7. Baffle; 8. Digital display device; 201. Suction tube; 202. Locking block; 203. Piston rod; 204. Connecting rod; 205. Spring 2; 2011. Suction head; 101. Through hole; 9. Anti-slip pad. Detailed Implementation

[0019] This section will describe in detail the specific embodiments of the present utility model. The preferred embodiments of the present utility model are shown in the accompanying drawings. The purpose of the drawings is to supplement the textual description with graphics, so that people can intuitively and vividly understand each technical feature and the overall technical solution of the present utility model, but they should not be construed as limiting the scope of protection of the present utility model.

[0020] Reference Figure 1-4 This utility model discloses a capacity-controllable nucleic acid mass spectrometry adsorption resin pipette, comprising: a shell 1, an anti-slip pad 9 made of rubber material on the outer side wall of the shell 1 to improve the stability of the operator holding the shell 1, an aspiration unit 2 at the lower end of the shell 1, a pull rod 3 slidably connected to the upper end of the shell 1, a hexagonal knob 4 fixedly connected to the upper end of the pull rod 3, a threaded rod 5 fixedly connected to one end of the pull rod 3 inside the shell 1, the threaded rod 5 passing through and threadedly connected to a baffle 7, a spring 6 fixedly connected to the inner top wall of the shell 1 and sleeved on the outer side of the pull rod 3, a baffle 7 fixedly connected to the inner wall of the shell 1 and located at the lower end of the spring 6, a digital display device 8 installed inside the shell 1, and the digital display device 8 is a prior art digital display consisting of a number wheel and a transmission gear, a through hole 101 on the outer side wall of the shell 1, the through hole 101 being located on one side of the digital display device 8, allowing the operator to easily observe the numbers on the digital display device 8;

[0021] The aspiration unit 2 includes an aspiration tube 201 fixedly connected to the lower end of the outer casing 1. The aspiration tube 201 penetrates the outer casing 1, and a suction head 2011 is installed at the lower end of the aspiration tube 201. The suction head 2011 is fitted onto the outer wall of the aspiration tube 201. A negative pressure is generated inside the aspiration tube 201, thereby drawing the sample into the suction head 201. A locking block 202 is fixedly connected to the outer wall of the aspiration tube 201 located inside the outer casing 1. A piston rod 203 is slidably connected to the inner wall of the aspiration tube 201. A connecting rod 204 is fixedly connected to one end of the piston rod 203. The end of the connecting rod 204 away from the piston rod 203 passes through the digital display device 8 and is in contact with the bottom end of the threaded rod 5. The movement of the threaded rod 5 drives the connecting rod 204 to move, thereby moving the piston rod 203 within the aspiration tube 201, facilitating sample aspiration. A spring 205 is fixedly connected to the lower end of the connecting rod 204, located on the outer wall of the piston rod 203. The aspiration unit 2 facilitates the aspiration of sample materials.

[0022] Working principle: In use, install the suction head 2011 onto the suction tube 201. Then, rotate the hexagonal knob 4 according to the required suction volume. The hexagonal knob 4 drives the threaded rod 5 at the lower end of the pull rod 3 to rotate. The threaded rod 5 is connected to the baffle 7 via a thread, thereby adjusting the pressing height of the pull rod 3. The pressing height is related to the material suction capacity; the higher the pressing, the greater the suction capacity. Furthermore, the rotation of the hexagonal knob 4 also drives the digital wheel in the digital display device 8 to rotate, facilitating observation of the rotation of the hexagonal knob 4 by the operator. When suctioning material, press the hexagonal knob 4 to compress the spring 6 and insert the suction head 2011 into the material container. Then release the hexagonal knob 4. At this time, a negative pressure is generated in the suction tube 201. This negative pressure causes the external resin particles to be sucked into the suction head 2011. Do not release the hexagonal knob 4 before discharge to maintain the internal negative pressure. When discharging the suctioned material, press the hexagonal knob 4 to compress the spring 6 and the second spring 205, which helps to push the piston rod 203 to move, thereby discharging the material.

[0023] The embodiments of the present utility model have been described in detail above with reference to the accompanying drawings. However, the present utility model is not limited to the above embodiments. Within the scope of knowledge possessed by those skilled in the art, various changes can be made without departing from the spirit of the present utility model.

Claims

1. A capacity-controllable nucleic acid mass spectrometry adsorption resin pipette, comprising: The outer shell (1) is characterized in that a suction unit (2) is provided at the lower end of the outer shell (1), a pull rod (3) is slidably connected to the upper end of the outer shell (1), a hexagonal knob (4) is fixedly connected to the upper end of the pull rod (3), a threaded rod (5) is fixedly connected to one end of the pull rod (3) inside the outer shell (1), a spring (6) is fixedly connected to the inner top wall of the outer shell (1) and sleeved on the outer side of the pull rod (3), a baffle (7) is fixedly connected to the inner wall of the outer shell (1) and located at the lower end of the spring (6), and a digital display device (8) is installed inside the outer shell (1). The suction unit (2) includes a suction tube (201) fixedly connected to the lower end of the outer shell (1). The suction tube (201) passes through the outer shell (1). A locking block (202) is fixedly connected to the outer wall of one end of the suction tube (201) inside the outer shell (1). A piston rod (203) is slidably connected to the inner wall of the suction tube (201). A connecting rod (204) is fixedly connected to one end of the piston rod (203). A spring (205) is fixedly connected to the lower end of the connecting rod (204) and located on the outer wall of the piston rod (203).

2. The capacity-controllable nucleic acid mass spectrometry adsorption resin pipette according to claim 1, characterized in that, The end of the connecting rod (204) away from the piston rod (203) passes through the digital display device (8) and is attached to the bottom end of the threaded rod (5).

3. The nucleic acid mass spectrometry adsorption resin pipette with controllable capacity according to claim 1, characterized in that, The lower end of the suction tube (201) is equipped with a suction head (2011), which is fitted onto the outer wall of the suction tube (201).

4. The capacity-controllable nucleic acid mass spectrometry adsorption resin pipette according to claim 1, characterized in that, The outer wall of the outer casing (1) is provided with a through hole (101), which is located on one side of the digital display device (8).

5. The capacity-controllable nucleic acid mass spectrometry adsorption resin pipette according to claim 1, characterized in that, The outer side wall of the outer shell (1) is provided with an anti-slip pad (9), which is made of rubber material.

6. The nucleic acid mass spectrometry adsorption resin pipette with controllable capacity according to claim 1, characterized in that, The threaded rod (5) passes through the baffle (7) and is threadedly connected to it.

Images