Guide wire and in-vivo conveying system
By introducing a flexible section into the guidewire, the problem of balancing flexibility and maneuverability in blood vessels is solved, enabling the guidewire to self-adaptively bend and contract in blood vessels, reducing vascular damage and improving passage.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- WUHAN VICKOR MEDICAL TECH CO LTD
- Filing Date
- 2024-12-24
- Publication Date
- 2026-05-08
AI Technical Summary
Existing guidewires struggle to simultaneously provide good maneuverability and pushing force at both the flexible tip and proximal end when navigating particularly tortuous blood vessels, resulting in limitations when entering the vessel.
Design a guidewire including a main body, a front end, and a flexible part. The flexibility of the flexible part is greater than that of the main body and the front end. The flexible part is provided between the main body and the front end or at the front end. The elastic modulus of the material of the flexible part is less than that of the main body and the front end. Alternatively, the flexibility can be improved by reducing the cross-sectional area of the flexible part or forming a groove at the flexible part, thereby achieving adaptive bending and contraction.
It improves the guidewire's adaptability in blood vessels, reduces damage to the vessel wall, and makes it easier to pass through blood vessels, thus enhancing the guidewire's flexibility and maneuverability in blood vessels.
Smart Images
Figure CN224207208U_ABST
Abstract
Description
Technical Field
[0001] This application relates to the field of medical device technology, and in particular to a guidewire and in vivo delivery system. Background Technology
[0002] A guidewire is a medical device used to guide catheters, stents, and other medical devices to target sites within blood vessels and other cavities. During surgery, when the guidewire passes through particularly tortuous blood vessels, its angle needs to be adjusted constantly to ensure smooth passage.
[0003] In intra-aortic balloon counterpulsation (IACP), the J-tip guidewire used with the IACP catheter needs to have a flexible tip while maintaining good maneuverability and pushing force at the proximal end. However, due to the complexity of the lesion site and the tortuous nature of the blood vessel itself, traditional straight or curved guidewires struggle to simultaneously achieve these properties, which limits their effectiveness when entering the blood vessel. Utility Model Content
[0004] This application provides a guidewire and in vivo delivery system to solve the problem that existing guidewires are limited by their structural dimensions and therefore lack adaptive adjustment capabilities.
[0005] To solve the above-mentioned technical problems, one technical solution adopted in this application is to provide a guidewire. The guidewire includes a main body, a front end, and a flexible part. The main body is straight, the front end is curved, and the flexible part is connected between the main body and the front end; or the main body is connected to the front end, and the flexible part is disposed at the front end; wherein the flexibility of the flexible part is greater than the flexibility of the main body and the front end.
[0006] In some embodiments, the outer diameter of the cross-section of the main body, the front end, and the flexible part is the same, and the elastic modulus of the material of the flexible part is less than that of the main body and the front end.
[0007] In some embodiments, the main body, the front end, and the flexible part are made of the same material, and the cross-sectional area of the flexible part is smaller than that of the main body and the front end.
[0008] In some embodiments, the outer diameter of the flexible portion is smaller than the outer diameter of the main body portion and the front end portion.
[0009] In some embodiments, the ratio of the outer diameter of the flexible portion to the outer diameter of the main body portion and the front end portion is 0.4-0.8.
[0010] In some embodiments, the guidewire forms a groove opposite to the flexible portion, the groove being located on the concave side of the front end portion.
[0011] In some embodiments, the groove is V-shaped or square-shaped.
[0012] In some embodiments, the front end portion includes a curved segment and a straight segment connected together, the straight segment being parallel to the main body portion, and the flexible portion being connected between the curved segment and the main body portion; or the flexible portion being disposed on the curved segment; or the flexible portion being connected between the curved segment and the straight segment.
[0013] To solve the above-mentioned technical problems, another technical solution adopted in this application is to provide an in vivo delivery system. The in vivo delivery system includes the guidewire as described above.
[0014] The beneficial effects of this application are as follows: Unlike the prior art, this application discloses a guidewire and an in vivo delivery system. By providing a flexible portion between the main body and the tip of the guidewire, or by providing a flexible portion at the tip, wherein the flexibility of the flexible portion is greater than that of the main body and the tip, the tip can adaptively bend and contract when it touches the inner wall of the blood vessel, thereby reducing damage to the inner wall of the blood vessel. It can also relatively reduce the size of the tip in the width direction, thereby making it easier to pass through the blood vessel, wherein the width direction is perpendicular to the extension direction of the main body. Attached Figure Description
[0015] To more clearly illustrate the technical solutions in the embodiments of this application or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this application. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort, wherein:
[0016] Figure 1 This is a schematic diagram of the structure of the guidewire embodiment one provided in this application;
[0017] Figure 2 Is it like this? Figure 1 A schematic diagram of the cross-sectional structure of the guidewire shown;
[0018] Figure 3 Is it like this? Figure 1 A schematic diagram showing the structure in which the front end of the guidewire bends and contracts.
[0019] Figure 4 This is a schematic diagram of the structure of the guidewire embodiment two provided in this application;
[0020] Figure 5 This is a schematic diagram of the guidewire in embodiment three provided in this application;
[0021] Figure 6 This is a schematic diagram of the structure of the guidewire in embodiment four provided in this application;
[0022] Figure 7 This is a schematic diagram of the structure of the guidewire embodiment five provided in this application. Detailed Implementation
[0023] The technical solutions of the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only a part of the embodiments of this application, and not all of the embodiments. Based on the embodiments of this application, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the scope of protection of this application.
[0024] The terms "first," "second," and "third" used in the embodiments of this application are for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of indicated technical features. Thus, a feature defined as "first," "second," or "third" may explicitly or implicitly include at least one of that feature. In the description of this application, "multiple" means at least two, such as two, three, etc., unless otherwise explicitly specified. Furthermore, the terms "comprising" and "having," and any variations thereof, are intended to cover non-exclusive inclusion. For example, a process, method, system, product, or device that includes a series of steps or units is not limited to the listed steps or units, but may optionally include steps or units not listed, or may optionally include other steps or units inherent to these processes, methods, products, or devices.
[0025] In this document, the term "embodiment" means that a particular feature, structure, or characteristic described in connection with an embodiment may be included in at least one embodiment of this application. The appearance of this phrase in various places throughout the specification does not necessarily refer to the same embodiment, nor is it a mutually exclusive, independent, or alternative embodiment. It will be explicitly and implicitly understood by those skilled in the art that the embodiments described herein can be combined with other embodiments.
[0026] This application provides a guidewire 100, see reference. Figures 1 to 3 , Figure 1 This is a schematic diagram of the structure of an embodiment of the guidewire provided in this application. Figure 2 Is it like this? Figure 1 The diagram shows the cross-sectional structure of the guidewire. Figure 3 Is it like this? Figure 1 The diagram shows the structure where the front end of the guidewire bends and contracts.
[0027] The guidewire 100 is divided into layers, including a core wire 101 and a resin layer 102 covering the core wire 101, and the whole structure is J-shaped.
[0028] The core wire 101 can be made of stainless steel or nickel-titanium alloy, which can provide the necessary support and maneuverability, allowing medical personnel to precisely control the direction of the guide wire 100 during minimally invasive surgery; the resin layer 102 can give the guide wire 100 flexibility, lubricity and good biocompatibility, and can be made of resin materials such as polytetrafluoroethylene (PTFE) or polylactic acid.
[0029] In minimally invasive surgical procedures, guidewire 100 is used to initially explore and establish a safe path from the skin inlet to the target lesion area. With the pre-positioned guidewire 100, subsequent catheters and other instruments can smoothly reach their destination along this path.
[0030] The existing guidewire only includes a straight main body 10 and a curved tip 20. When the tip 20 collides with the inner wall of the blood vessel, it can deform to a certain extent due to the flexibility of the tip 20 itself and the main body 10, which cannot achieve a greater degree of contraction to avoid damage to the inner wall of the blood vessel and facilitate passage through the blood vessel.
[0031] See Figure 1 and Figure 3 In this embodiment, the guidewire 100 is divided according to its shape and structure, including a main body 10, a front end 20 and a flexible part 30. The main body 10 is straight, the front end 20 is curved, and the flexible part 30 is connected between the main body 10 and the front end 20; or the main body 10 is connected to the front end 20, and the flexible part 30 is disposed on the front end 20; wherein, the flexibility of the flexible part 30 is greater than the flexibility of the main body 10 and the front end 20.
[0032] Figure 3 In the diagram, the dashed line represents the state of the guidewire 100's front end 20 when it is not impacted, and it remains naturally extended; the solid line represents the state of the guidewire 100's front end 20 when it is impacted and it bends and contracts. It can be seen that the presence of the flexible part 30 allows the front end 20 to contract to a greater extent when it impacts the inner wall of the blood vessel, which can reduce the degree of impact on the blood vessel and make it easier to pass through the blood vessel.
[0033] The flexible portion 30 can be made more flexible than the main body portion 10 and the front end portion 20 by changing its material and shape. This allows it to adaptively bend and contract when the front end portion 20 touches the inner wall of the blood vessel, reducing damage to the inner wall. It can also relatively reduce the width of the front end portion 20, making it easier to pass through the blood vessel. The width direction is perpendicular to the extension direction of the main body portion 10.
[0034] Continue reading Figures 1 to 3 In some embodiments, the outer diameter of the cross-section of the main body 10, the front end 20 and the flexible part 30 is the same, and the elastic modulus of the material of the flexible part 30 is less than that of the main body 10 and the front end 20.
[0035] The cross-section of the guide wire 100 is circular, that is, the cross-sections of the main body 10, the front end 20 and the flexible part 30 are all circular and have the same outer diameter. However, the elastic modulus of the material in the flexible part 30 is less than that of the main body 10 and the front end 20.
[0036] For example, the elastic modulus of the resin layer 102 material at the flexible part 30 is smaller, that is, smaller than the elastic modulus of the resin layer 102 material at the main body 10 and the front end 20; or, the core wire 101 is omitted at the flexible part 30, and the flexible part 30 is composed entirely of resin layer 102, while the main body 10 and the front end 30 both include core wire 101 and resin layer 102.
[0037] By changing the material composition of the flexible part 30, the elastic modulus of the material of the flexible part 30 is made smaller than that of the main body 10 and the front end 20. This improves the flexibility of the flexible part 30 while keeping the shape of the guide wire 100 unchanged, so that the front end 20 can bend and contract from the flexible part 30 when it is hit.
[0038] See Figure 4 , Figure 4 This is a schematic diagram of the second embodiment of the guidewire provided in this application.
[0039] In another embodiment, the main body 10, the front end 20, and the flexible part 30 are made of the same material, and the cross-sectional area of the flexible part 30 is smaller than that of the main body 10 and the front end 20.
[0040] In other words, the main body 10, the front end 20, and the flexible part 30 all include a core wire 101 and a resin layer 102. By changing the shape and structure of the flexible part 30, that is, by reducing the cross-sectional area of the flexible part 30, the flexibility of the flexible part 30 is improved.
[0041] Optionally, the flexible portion 30 has a circular cross-section, and the outer diameter of the flexible portion 30 is smaller than the outer diameter of the main body portion 10 and the front end portion 20. In other words, the flexibility of the flexible portion 30 is enhanced by reducing its diameter, making it easier to bend at the flexible portion 30, thereby helping the front end portion 30 to bend and shrink when necessary.
[0042] For example, the ratio of the outer diameter of the flexible part 30 to the outer diameter of the main body 10 and the front end 20 is 0.4-0.8, and this ratio can specifically be 0.4, 0.5, 0.6, 0.7 or 0.8. The outer diameter of the flexible part 30 refers to the outer diameter of its smallest cross-section.
[0043] See Figure 5 , Figure 5 This is a schematic diagram of the structure of the guidewire embodiment three provided in this application.
[0044] Optionally, the guidewire 100 has a groove 31 formed opposite to the flexible portion 30, and the groove 31 is located on the concave side of the front end portion 10. The front end portion 10 is curved and has a concave side and a convex side formed opposite to each other. The groove 31 is located on the concave side of the front end portion 10, that is, the flexible portion 330 can improve its flexibility by reducing part of its cross-sectional area, making it easier to bend at the flexible portion 30, thereby helping the front end portion 30 to bend and retract when necessary.
[0045] Specifically, the groove 30 can be V-shaped or square-shaped.
[0046] See Figure 2 The front end portion 20 includes a curved section 21 and a straight section 22 connected together. The straight section 22 is parallel to the main body portion 10. The flexible portion 30 is connected between the curved section 21 and the main body portion 10, so that the curved section 21 and the straight section 22 can bend and contract together when they encounter a blood vessel; or refer to Figure 6 The flexible part 30 is provided in the curved section 21, so that the curved section 21 and the straight section 22 can bend and contract together when they encounter a blood vessel; or refer to Figure 7 The flexible part 30 is connected between the curved section 21 and the straight section 22, so that the straight section 22 can bend and contract relatively when it encounters a blood vessel.
[0047] Based on this, this application also provides an in vivo delivery system (not shown), which includes a guidewire 100 as described above. In this in vivo delivery system, a guiding sheath punctures a blood vessel to establish a puncture channel, the guidewire 100 establishes a safe path to the target location through the puncture channel of the guiding sheath, a catheter is advanced along the path of the guidewire 100 to the target location, and a treatment device is delivered to the target location along the catheter and the guidewire 100. The medical device may be an occluder or a shunt, etc.
[0048] Unlike existing technologies, this application discloses a guidewire and an in vivo delivery system. By providing a flexible portion between the main body and the tip of the guidewire, or by providing a flexible portion at the tip, wherein the flexibility of the flexible portion is greater than that of the main body and the tip, the tip can adaptively bend and contract when it touches the inner wall of the blood vessel, thereby reducing damage to the inner wall of the blood vessel. It can also relatively reduce the size of the tip in the width direction, thereby making it easier to pass through the blood vessel, wherein the width direction is perpendicular to the extension direction of the main body.
[0049] The above description is merely an embodiment of this application and does not limit the patent scope of this application. Any equivalent structural or procedural transformations made using the content of this application's specification and drawings, or direct or indirect applications in other related technical fields, are similarly included within the patent protection scope of this application.
Claims
1. A guidewire, characterized in that, The guidewire includes a main body, a front end, and a flexible part. The main body is straight, the front end is curved, and the flexible part connects the main body and the front end; or The main body is connected to the front end, and the flexible part is disposed at the front end; The flexibility of the flexible part is greater than that of the main body and the front end.
2. The guidewire according to claim 1, characterized in that, The main body, the front end, and the flexible part have the same cross-sectional outer diameter, and the elastic modulus of the flexible part material is less than that of the main body and the front end.
3. The guidewire according to claim 1, characterized in that, The main body, the front end, and the flexible part are all made of the same material, and the cross-sectional area of the flexible part is smaller than that of the main body and the front end.
4. The guidewire according to claim 3, characterized in that, The outer diameter of the flexible part is smaller than the outer diameter of the main body and the front end.
5. The guidewire according to claim 4, characterized in that, The ratio of the outer diameter of the flexible section to the outer diameter of the main body and the front end section is 0.4-0.
8.
6. The guidewire according to claim 3, characterized in that, The guide wire forms a groove at the flexible portion, and the groove is located on the concave side of the front end portion.
7. The guidewire according to claim 6, characterized in that, The groove is V-shaped or square-shaped.
8. The guidewire according to any one of claims 1 to 7, characterized in that, The front end portion includes a connected curved section and a straight section, the straight section being parallel to the main body, and the flexible portion connecting the curved section and the main body; or The flexible portion is disposed on the curved section; or The flexible section connects the curved section and the straight section.
9. An in vivo delivery system, characterized in that, The in vivo delivery system includes the guidewire as described in any one of claims 1 to 8.