Liquid-based cell preservation bottle

Abstract

The utility model relates to the technical field of medical instruments, and particularly discloses a liquid-based cell preservation bottle which is characterized in that a lower joint detachably sleeved and matched with a bottle opening of a lower bottle body is arranged at the bottom end of an upper bottle body, an upper joint is arranged in the middle of the top surface of the upper bottle body, and a plurality of spikes are arranged on the inner peripheral wall of the upper bottle body; and the top cover is detachably sleeved on the upper joint. And a filter screen plate is arranged on the inner peripheral wall of the lower bottle body close to the bottle opening. The opening of the lower connector is covered with a lower sealing membrane, and the opening of the upper connector is covered with an upper sealing membrane. The problem that the liquid-based cell holding bottle is inconvenient to fully collect sample cells and take liquid for detection is well solved.

Description

Technical Field

[0001] This utility model relates to the field of medical device technology, specifically to liquid-based cell preservation bottles. Background Technology

[0002] Liquid-based cytology is a cell type used in cell sample processing techniques for detection. This technology is primarily based on liquid-based thin-layer cell systems, which use special processing methods to preserve collected cell samples in a liquid for subsequent detection and analysis.

[0003] Currently, widely used liquid-based cell preservation bottles consist of a bottle body and a cap, which are connected by a threaded connection. In use, cell tissue is first collected using a brush, then the brush head is inserted into the bottle body, stirred, and rotated. Finally, the brush head is removed, and the cap is tightened. For testing, a syringe pipette is used to puncture the liquid-based cell preservation bottle to extract the sample. However, this method makes it difficult to ensure that all sample cells are fully expelled into the preservation solution within the bottle; furthermore, syringe pipettes are not easily punctured for sample extraction and testing, making them inconvenient to use. Utility Model Content

[0004] The purpose of this invention is to provide a liquid-based cell preservation bottle to solve the problem that current liquid-based cell preservation bottles are not convenient for fully collecting sample cells and extracting liquid for testing.

[0005] To achieve the above objectives, this utility model provides the following technical solution: a liquid-based cell preservation bottle, wherein the bottom end of the upper bottle body is provided with a lower connector that can be detachably fitted and matched with the bottle mouth of the lower bottle body, the upper bottle body is provided with an upper connector in the middle of the top surface, and the inner peripheral wall of the upper bottle body is provided with a plurality of protrusions; the top cover is detachably fitted onto the upper connector.

[0006] Preferably, a filter screen is provided on the inner peripheral wall of the lower bottle near the bottle opening.

[0007] Preferably, the opening of the lower connector is covered with a lower sealing diaphragm, and the outer edge of the lower sealing diaphragm is provided with strips.

[0008] Preferably, the opening of the upper connector is covered with an upper sealing diaphragm.

[0009] Preferably, both the lower sealing diaphragm and the upper sealing diaphragm are tin films.

[0010] Preferably, the bottom of the lower bottle body is provided with a funnel-shaped cavity.

[0011] Preferably, the lower connector is threaded to the bottle opening of the lower bottle body, and the upper connector is threaded to the top cover.

[0012] Compared with the prior art, the beneficial effects of this utility model are:

[0013] 1. The liquid-based cell preservation bottle of this utility model rotates the brush head containing collected cell tissue inside the upper bottle with internal spikes, so as to facilitate the full detachment of cell tissue and facilitate the full collection of sample cells.

[0014] 2. When performing liquid-based cell preservation vials, the liquid can be retrieved by simply opening the top cap and inserting a syringe pipette into the upper connector, thus improving the convenience of liquid retrieval and testing. Attached Figure Description

[0015] Figure 1 This is a cross-sectional view of the overall structure of this utility model;

[0016] Figure 2 This is a schematic diagram of the three-dimensional structure of the bottle in this practical application.

[0017] In the diagram: 1 - lower bottle body; 1.1 - funnel-shaped cavity;

[0018] 2-Upper bottle body; 2.1-Lower connector; 2.2-Upper connector; 2.3-Spike;

[0019] 3-Top cover;

[0020] 4-Filter screen;

[0021] 5-Lower sealing diaphragm; 5.1-Sheet strip;

[0022] 6- Upper sealing diaphragm. Detailed Implementation

[0023] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0024] Please see Figure 1-2 The liquid-based cell preservation bottle has a filter screen 4 installed on the inner wall of the lower bottle body 1 near the bottle mouth.

[0025] The upper bottle 2 has a lower connector 2.1 at its bottom end that can be detachably fitted to the opening of the lower bottle 1. An upper connector 2.2 is located in the middle of the top surface of the upper bottle 2. Several protrusions 2.3 are provided on the inner circumferential wall of the upper bottle 2. The top cap 3 is detachably fitted onto the upper connector 2.2. The opening of the lower connector 2.1 is covered with a lower sealing diaphragm 5, and the outer edge of the lower sealing diaphragm 5 has strips 5.1. The opening of the upper connector 2.2 is covered with an upper sealing diaphragm 6. Both the lower sealing diaphragm 5 and the upper sealing diaphragm 6 are tin films. The lower connector 2.1 is threadedly fitted to the opening of the lower bottle 1, and the upper connector 2.2 is threadedly fitted to the top cap 3. The base liquid is sealed inside the upper bottle 2.

[0026] In summary, the brush head is used to collect sample cells and tissues. The upper bottle 2 and the lower bottle 1 are separated. The upper bottle 2 is inverted, and the lower sealing film 5 is peeled off through the strip 5.1. Then, the brush head is inserted into the upper bottle 2 and rotated. Due to the presence of the spikes 2.3, the cells and tissues on the brush head can be fully detached into the base fluid of the upper bottle 2.

[0027] After removing the brush head, reassemble the lower bottle 1 and the upper bottle 2, and place the entire storage bottle upright. The base liquid containing the sample cells and tissues will then seep into the bottom of the inner cavity of the lower bottle 1 under the filtering action of the filter screen 4.

[0028] When liquid sampling is required, first remove the top cap 3 from the upper connector 2.2, then pierce the upper sealing membrane 6 with the needle of the syringe pipette, and then pierce the filter screen 4 before inserting the needle into the bottom of the lower bottle 1 to collect the liquid. Alternatively, the sealing membrane 6 and the filter screen 4 can be pierced first before inserting the syringe pipette needle for liquid sampling.

[0029] To improve the centrifugation efficiency during the centrifugation process of liquid-based cell preservation bottles, a funnel-shaped cavity 1.1 is provided at the bottom of the lower bottle body 1.

[0030] It should be noted that, in this document, relational terms such as "first" and "second" are used only to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such process, method, article, or apparatus.

[0031] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A liquid-based cell preservation bottle, characterized in that, include: Lower bottle body(1); The upper bottle body (2) has a lower connector (2.1) at the bottom end that is detachably fitted to the bottle mouth of the lower bottle body (1), an upper connector (2.2) at the middle of the top surface of the upper bottle body (2), and several protrusions (2.3) on the inner peripheral wall of the upper bottle body (2). Top cover (3), which is detachably mounted on the upper connector (2.2).

2. The liquid-based cell preservation bottle according to claim 1, characterized in that: The lower bottle body (1) has a filter screen (4) on its inner peripheral wall near the bottle mouth.

3. The liquid-based cell preservation bottle according to claim 1, characterized in that: The opening of the lower connector (2.1) is covered with a lower sealing diaphragm (5), and the outer edge of the lower sealing diaphragm (5) is provided with a strip (5.1).

4. The liquid-based cell preservation bottle according to claim 3, characterized in that: The opening of the upper connector (2.2) is covered with an upper sealing diaphragm (6).

5. The liquid-based cell preservation bottle according to claim 4, characterized in that: Both the lower sealing diaphragm (5) and the upper sealing diaphragm (6) are tin films.

6. The liquid-based cell preservation bottle according to claim 1, characterized in that: The bottom of the lower bottle body (1) is provided with a funnel-shaped cavity (1.1).

7. The liquid-based cell preservation bottle according to claim 1, characterized in that: The lower connector (2.1) is threadedly connected to the bottle opening of the lower bottle body (1), and the upper connector (2.2) is threadedly connected to the top cover (3).

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