Isolator with positive and negative pressure dual-sealing structure
By designing a dual positive and negative pressure sealing structure, the problem of easy failure of the sealing structure of the isolator under alternating positive and negative pressure fluctuations is solved, thereby improving the sealing performance and the long-term operational stability of the equipment.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- HEBEI FANDU MASCH TECH CO LTD
- Filing Date
- 2025-07-30
- Publication Date
- 2026-05-26
AI Technical Summary
During the alternating positive and negative pressure fluctuations, the sealing structure of the isolator is prone to fatigue failure, leading to leakage risks and affecting the stability of the sterile environment and the cleanliness of materials.
A dual-seal structure with positive and negative pressure is designed, including components such as a sealing strip, a first sliding plate, a sliding plug, and a spring. Through an adaptive expansion and delayed movement mechanism, it ensures that the sealing strip fits tightly against the isolation door under positive and negative pressure, reducing friction and wear and extending service life.
It significantly enhances sealing performance, improves the operational stability and safety of the isolator under complex process conditions, and reduces the risk of wear and leakage of the seals.
Smart Images

Figure CN224278963U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of isolator technology, and in particular to an isolator with a double sealing structure for positive and negative pressure. Background Technology
[0002] In the production of sterile active pharmaceutical ingredients (APIs), isolators are crucial equipment for achieving high-cleanliness operations and are widely used in key stages such as material feeding and dispensing. With the increasing demands for sterility in the biopharmaceutical industry, isolators play a vital role in protecting materials from microbial and particulate contamination. However, in actual operation, frequent pressure fluctuations within the isolator are common, especially during operations involving the opening and closing of pneumatic valves, airflow disturbances during material transport, and the activation of pressure compensation systems, often resulting in alternating fluctuations between positive and negative pressure.
[0003] These frequent pressure fluctuations can cause continuous impacts on the sealing structure of the isolator, leading to seal fatigue, deformation, or even partial failure, thus increasing the risk of leakage. Once the sealing performance deteriorates, it will not only disrupt the stability of the clean environment inside the isolator, but may also cause material contamination, cross-contamination, and even affect the sterility assurance level of the entire batch of products. Utility Model Content
[0004] To overcome the problems mentioned above, this utility model provides an isolator with a double sealing structure of positive and negative pressure.
[0005] The technical solution is as follows: an isolator with a dual positive and negative pressure sealing structure, including an isolation box, an isolation door slidably disposed on the isolation box, a sliding frame slidably disposed on the isolation box, the sliding frame being hinged to the isolation door, a first spring being fixedly connected between the sliding frame and the isolation box, a sealing strip being fixedly connected to the isolation box, the sealing strip contacting the isolation door, and the isolation box being provided with a positive pressure sealing structure and a negative pressure sealing structure, both of which are used to increase the compressive force between the sealing strip and the isolation door.
[0006] Preferably, the isolation door is provided with an arc-shaped groove, the sealing strip is provided with an annular cavity filled with gas, the inner side of the sealing strip is arc-shaped, and the arc-shaped surface of the sealing strip is used to insert into the arc-shaped groove of the isolation door.
[0007] Preferably, the positive pressure sealing structure includes a first fixed shell, which is fixedly connected to the inner wall of the isolation box. A conduit connects the first fixed shell and the sealing strip. A first sliding plate is slidably disposed inside the first fixed shell, and a second spring is fixedly connected between the first sliding plate and the first fixed shell.
[0008] Preferably, the negative pressure sealing structure includes a second fixed shell, which is embedded in the isolation box. The two sides of the second fixed shell are located on the inner and outer sides of the isolation box, respectively. A sliding plug is slidably disposed inside the second fixed shell. A third spring is fixedly connected between the sliding plug and the second fixed shell. The sliding plug and the second fixed shell form an air storage cavity. A conduit connects the air storage cavity and the annular cavity of the sealing strip.
[0009] Preferably, it further includes a third fixed shell, which is fixedly connected to the isolation box. The third fixed shell is fixedly connected to an air guide pipe, which is fixedly connected to and communicates with the annular cavity of the sealing strip. The third fixed shell and the air guide pipe are slidably provided with a second sliding plate. A tension spring is fixedly connected between the second sliding plate and the third fixed shell. The third fixed shell is slidably provided with a fixing frame fixedly connected to the second sliding plate, and the fixing frame is slidably provided with a sliding rod.
[0010] Preferably, a fourth spring is fixed between the fixing frame and the sliding rod, and the elastic coefficient of the fourth spring is greater than that of the tension spring.
[0011] Preferably, the second sliding plate is fixedly connected to a plurality of elastic blocks, and the elastic blocks are in contact with the inner wall of the third fixed shell.
[0012] This utility model has the following advantages:
[0013] 1. This utility model sets up a sealing strip structure with pressure self-adaptive function between the isolation box and the isolation door. When the pressure inside the isolation box is in a positive or negative pressure state, the sealing strip can expand moderately and fit tightly against the surface of the isolation door, thereby significantly enhancing the sealing performance between the two. This design effectively solves the technical problems of the traditional isolator's sealing structure being prone to failure under frequent pressure fluctuations and the clean environment being easily damaged, and improves the operational stability and safety of the equipment under complex process conditions.
[0014] 2. By setting a mechanism to delay the movement of the second sliding plate, the sealing strip is in a retracted state during the closing of the isolation door, thereby effectively reducing friction and wear between the sealing strip and the isolation door and significantly extending its service life;
[0015] 3. Through the synergistic effect of the fourth spring and the elastic block, especially the deformation range and damping characteristics of the elastic block, the moving speed of the second sliding plate is slowed down, so that the sealing strip gradually expands and adheres tightly to the door surface only after the isolation door is completely closed, thereby realizing the timing control of the sealing action and improving the overall sealing reliability and long-term operational stability of the isolator. Attached Figure Description
[0016] Figure 1This is a three-dimensional structural diagram of the present invention;
[0017] Figure 2 This is a three-dimensional structural diagram of the isolation door and sealing strip of this utility model;
[0018] Figure 3 This is a three-dimensional structural diagram of the first and second fixing shells of this utility model;
[0019] Figure 4 This is a cross-sectional view of the sealing strip and the first fixing shell of this utility model;
[0020] Figure 5 This is a cross-sectional view of the third fixed shell and sliding rod of this utility model.
[0021] Wherein: 1-Isolation box, 2-Isolation door, 3-Sliding frame, 4-First spring, 5-Sealing strip, 6-First fixed shell, 7-First sliding plate, 8-Second spring, 9-Second fixed shell, 10-Sliding plug, 11-Third spring, 12-Air storage chamber, 13-Third fixed shell, 14-Air guide pipe, 15-Second sliding plate, 16-Tension spring, 17-Fixed frame, 18-Sliding rod, 19-Fourth spring, 20-Elastic block. Detailed Implementation
[0022] To make the technical means, creative features, objectives and effects of this utility model easier to understand, the present utility model will be further described below in conjunction with specific embodiments.
[0023] In the description of this utility model, it should be understood that the terms "upper", "lower", "front", "rear", "left", "right", "top", "bottom", "inner", "outer", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model.
[0024] Example 1: Isolator with positive and negative pressure dual sealing structure, such as Figures 1-3As shown, the device includes an isolation box 1. An isolation door 2 is slidably mounted on the right side of the isolation box 1. The left side of the isolation door 2 has an inclined surface, which fits against the isolation box 1 to improve the sealing between the isolation box 1 and the isolation door 2. Two sliding brackets 3 are slidably mounted on the right side of the isolation box 1 (this number is shown in the attached figure; the actual number can be adjusted according to requirements, and the same applies to subsequent number representations). Both sliding brackets 3 are hinged to the isolation door 2. A first spring 4 is fixed between the sliding brackets 3 and the isolation box 1. A sealing strip 5 is fixed to the right side of the isolation box 1. The isolation door 2 has an arc-shaped groove. The sealing strip 5 has an annular cavity filled with gas inside. The inner side of the sealing strip 5 is arc-shaped, and the arc-shaped surface of the sealing strip 5 is used to insert into the arc-shaped groove of the isolation door 2. The isolation box 1 is equipped with a positive pressure sealing structure and a negative pressure sealing structure, both of which are used to increase the compressive force between the sealing strip 5 and the isolation door 2.
[0025] like Figures 2-4 As shown, the positive pressure sealing structure includes a first fixed shell 6, which is fixed to the inner wall of the isolation box 1 and is located above the isolation door 2. A conduit is connected between the right side of the first fixed shell 6 and the sealing strip 5. The conduit is embedded in the isolation box 1. A first sliding plate 7 is slidably arranged inside the first fixed shell 6. The first sliding plate 7 is provided with an annular sealing ring (not shown in the figure). A second spring 8 is fixedly connected between the first sliding plate 7 and the first fixed shell 6.
[0026] like Figures 2-4 As shown, the negative pressure sealing structure includes a second fixed shell 9, which is embedded in the isolation box 1. The two sides of the second fixed shell 9 are located on the inner and outer sides of the isolation box 1, respectively. A sliding plug 10 is slidably disposed inside the second fixed shell 9. The right side of the sliding plug 10 is exposed to the external environment of the isolation box 1. A third spring 11 is fixedly connected between the sliding plug 10 and the second fixed shell 9. The third spring 11 is located inside the second fixed shell 9. The sliding plug 10 and the second fixed shell 9 form an air storage cavity 12. A conduit is connected between the air storage cavity 12 and the annular cavity of the sealing strip 5. The conduit is embedded in the isolation box 1.
[0027] Working principle: The operator first pulls the isolation door 2 and the sliding frame 3 to move. The sliding frame 3 moves and compresses the first spring 4. Then the operator moves the isolation door 2 to about 90 degrees and pushes the isolation door 2 so that the isolation door 2 is inserted into the side wall of the isolation box 1. At the same time, under the elastic force of the first spring 4, the sliding frame 3 moves in the opposite direction to reset, completing the closing of the isolation door 2 (closing operation).
[0028] After the door closing operation is completed, the sealing strip 5 is located in the arc-shaped groove of the isolation door 2. Then, the corresponding operation is performed through the control panel on the isolation box 1. During the operation, if the pressure inside the isolation box 1 becomes high pressure, the increased pressure will squeeze the first sliding plate 7. The first sliding plate 7 moves to compress the second spring 8 and squeezes the gas in the first fixed shell 6 into the sealing strip 5 through the conduit, causing the pressure inside the sealing strip 5 to increase and expand. The expanded sealing strip 5 is tightly attached to the arc-shaped groove of the isolation door 2, improving the sealing between the isolation door 2 and the isolation box 1, and ensuring that the isolator works normally.
[0029] If the pressure inside the isolation chamber 1 becomes negative, the first sliding plate 7 moves in the opposite direction to reset under the elastic force of the second spring 8. At the same time, the negative pressure will move the adsorption sliding plug 10. The movement of the sliding plug 10 will compress the third spring 11. Simultaneously, the movement of the sliding plug 10 will squeeze the gas in the gas storage chamber 12 into the sealing strip 5 through the conduit, so that the sealing strip 5 remains expanded and tightly attached to the arc-shaped groove of the isolation door 2, thereby improving the operational stability and safety of the isolator under complex process conditions.
[0030] Example 2: Based on Example 1, such as Figures 3-5 As shown, it also includes a third fixed shell 13, which is fixedly connected to the isolation box 1. The third fixed shell 13 is located between the first fixed shell 6 and the second fixed shell 9. A vent pipe 14 is fixedly connected to the right side of the third fixed shell 13, and the left side of the vent pipe 14 is located inside the third fixed shell 13. The vent pipe 14 is fixedly connected to and communicates with the annular cavity of the sealing strip 5. A second sliding plate 15 is slidably arranged together with the third fixed shell 13 and the vent pipe 14. A tension spring 16 is fixedly connected between the right side of the second sliding plate 15 and the third fixed shell 13. The third fixed shell 13 is slidably equipped with a fixed frame 17 on the outside of the air guide tube 14. The right end of the fixed frame 17 is fixedly connected to the second sliding plate 15. The lower part of the fixed frame 17 is slidably equipped with a sliding rod 18. A fourth spring 19 is fixedly connected between the fixed frame 17 and the sliding rod 18. The fourth spring 19 is sleeved on the outside of the sliding rod 18. The elastic coefficient of the fourth spring 19 is greater than that of the tension spring 16. The second sliding plate 15 is fixedly equipped with four elastic blocks 20 that are circumferentially equidistant. The elastic blocks 20 are in contact with the inner wall of the third fixed shell 13.
[0031] Working principle: During the closing operation, when the isolation door 2 is inserted into the side wall of the isolation chamber 1, it simultaneously compresses the sliding rod 18 to move. The movement of the sliding rod 18 compresses the fourth spring 19. The elastic force of the fourth spring 19 drives the fixed frame 17 and the second sliding plate 15 to move. However, when the elastic block 20 moves, it generates damping with the inner wall of the third fixed shell 13, causing the second sliding plate 15 to move slowly. The movement of the second sliding plate 15 stretches the tension spring 16 and compresses the gas in the third fixed shell 13, which is then injected into the sealing strip 5 through the air guide pipe 14, causing the sealing strip 5 to expand slowly. Finally, after the isolation door 2 is completely closed, the sealing strip 5 gradually expands and embeds itself into the arc-shaped groove of the isolation door 2. Subsequently, the isolation chamber 1 is used to perform corresponding work, causing the pressure inside the isolation chamber 1 to change as described above, which again triggers the expansion of the sealing strip 5, enhancing the sealing performance between the isolation chamber 1 and the isolation door 2, and further improving the overall sealing reliability and long-term operational stability of the isolator.
[0032] The technical principles of the present invention have been described above with reference to specific embodiments. These descriptions are merely for explaining the principles of the present invention and should not be construed as limiting the scope of protection of the present invention in any way. Based on this explanation, those skilled in the art can conceive of other specific embodiments of the present invention without creative effort, and these embodiments will all fall within the scope of protection of the present invention.
Claims
1. An isolator with a double-sealed structure for positive and negative pressure, characterized in that, The device includes an isolation box (1), an isolation door (2) slidably mounted on the isolation box (1), a sliding frame (3) slidably mounted on the isolation box (1), the sliding frame (3) hinged to the isolation door (2), a first spring (4) fixedly connected between the sliding frame (3) and the isolation box (1), a sealing strip (5) fixedly connected to the isolation box (1), the sealing strip (5) contacting the isolation door (2), and the isolation box (1) being provided with a positive pressure sealing structure and a negative pressure sealing structure, both of which are used to increase the compressive force between the sealing strip (5) and the isolation door (2).
2. The isolator with a double-sealed structure under positive and negative pressure according to claim 1, characterized in that, The isolation door (2) is provided with an arc-shaped groove, the sealing strip (5) is provided with an annular cavity filled with gas, the inner side of the sealing strip (5) is set as arc-shaped, and the arc-shaped surface of the sealing strip (5) is used to insert into the arc-shaped groove of the isolation door (2).
3. The isolator with a double-sealed structure under positive and negative pressure according to claim 1, characterized in that, The positive pressure sealing structure includes a first fixed shell (6), which is fixed to the inner wall of the isolation box (1). A conduit is connected between the first fixed shell (6) and the sealing strip (5). A first sliding plate (7) is slidably arranged inside the first fixed shell (6), and a second spring (8) is fixed between the first sliding plate (7) and the first fixed shell (6).
4. The isolator with a double-sealed structure under positive and negative pressure according to claim 1, characterized in that, The negative pressure sealing structure includes a second fixed shell (9), which is embedded in the isolation box (1). The two sides of the second fixed shell (9) are located on the inner and outer sides of the isolation box (1), respectively. A sliding plug (10) is slidably disposed inside the second fixed shell (9). A third spring (11) is fixed between the sliding plug (10) and the second fixed shell (9). The sliding plug (10) and the second fixed shell (9) form an air storage cavity (12). A conduit is connected between the air storage cavity (12) and the annular cavity of the sealing strip (5).
5. The isolator with a double-sealed structure under positive and negative pressure according to claim 1, characterized in that, It also includes a third fixed shell (13), which is fixedly connected to the isolation box (1). The third fixed shell (13) is fixedly connected to an air guide pipe (14). The air guide pipe (14) is fixedly connected to and communicates with the annular cavity of the sealing strip (5). The third fixed shell (13) and the air guide pipe (14) are slidably provided with a second sliding plate (15). A tension spring (16) is fixedly connected between the second sliding plate (15) and the third fixed shell (13). The third fixed shell (13) is slidably provided with a fixing frame (17) fixedly connected to the second sliding plate (15). The fixing frame (17) is slidably provided with a sliding rod (18).
6. The isolator with a double-sealed structure for positive and negative pressure according to claim 5, characterized in that, A fourth spring (19) is fixed between the fixed frame (17) and the sliding rod (18), and the elastic coefficient of the fourth spring (19) is greater than that of the tension spring (16).
7. The isolator with a double-sealed structure for positive and negative pressure as described in claim 6, characterized in that, The second sliding plate (15) is fixed with a plurality of elastic blocks (20), and the elastic blocks (20) are in contact with the inner wall of the third fixed shell (13).