A rapid reaction device for qPCR detection reagents

By combining finned hot and cold air blowers with temperature sensors, the problems of slow temperature control and poor heat dissipation in qPCR devices were solved, achieving the requirements of rapid response and spatial flexibility, improving detection efficiency and extending device life.

CN224280293UActive Publication Date: 2026-05-26怒江傈僳族自治州草果产业创新发展中心

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
怒江傈僳族自治州草果产业创新发展中心
Filing Date
2025-06-27
Publication Date
2026-05-26

AI Technical Summary

Technical Problem

Existing qPCR devices have slow temperature control, large size, and poor heat dissipation, making it difficult to meet the requirements of rapid reaction and space flexibility.

Method used

The finned hot and cold air blower works in conjunction with a temperature sensor to achieve rapid temperature adjustment and precise control. Combined with a honeycomb breathable panel, it improves heat dissipation efficiency. The compact design of the components makes it suitable for use in small laboratories.

Benefits of technology

It achieves rapid and precise temperature regulation, improves detection efficiency, adapts to the space requirements of small laboratories, and extends the service life of the device.

✦ Generated by Eureka AI based on patent content.

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Abstract

This invention provides a rapid reaction device for qPCR detection reagents, belonging to the field of biotechnology. It includes a housing with a temperature control component on one side and a reagent placement component on the top. Through the temperature control component, the fins, acting as efficient heat exchangers, rapidly absorb and release heat. When hot air passes through the fins, heat is quickly transferred to the entire inner chamber, raising the internal temperature. When cold air passes through, the fins absorb heat and transfer it to the cold air, thus lowering the internal temperature. The combination of hot and cold air blowers and the fins allows for rapid response to temperature regulation needs, achieving precise temperature control within the housing, meeting the requirements of rapid qPCR detection reagent reactions, and improving detection efficiency.
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Description

Technical Field

[0001] This utility model relates to the field of biotechnology, and more specifically, to a rapid reaction device for qPCR detection reagents. Background Technology

[0002] qPCR (real-time quantitative polymerase chain reaction) technology emerged in the 1990s and is a novel nucleic acid quantification technique developed based on traditional PCR technology. With the rapid development of molecular biology techniques, qPCR technology has been widely used in various fields of life science research due to its advantages such as high sensitivity, high specificity, and accurate quantification. qPCR has become an indispensable tool for gene expression analysis, pathogen detection, and genomics research. Due to its high sensitivity and specificity, qPCR technology is widely used in clinical, food safety, and environmental monitoring fields.

[0003] The existing technology still has the following drawbacks:

[0004] (1) qPCR reaction has extremely strict requirements for temperature conditions. When it is necessary to raise or lower the temperature of the device, the temperature adjustment speed is slow and cannot meet the requirements of the rapid reaction of qPCR detection reagent for the timeliness of temperature adjustment.

[0005] (2) Existing qPCR detection devices are generally large in size and not flexible in space utilization, which makes them difficult to adapt to the limited experimental space of small laboratories. Existing devices may have poor heat dissipation during operation, leading to overheating of the equipment, which in turn affects the performance and service life of the device.

[0006] Therefore, we have made improvements to this and proposed a rapid reaction device for qPCR detection reagents. Utility Model Content

[0007] The purpose of this invention is to address the problems of slow temperature control adjustment speed, large size, and poor heat dissipation in existing qPCR detection devices.

[0008] To achieve the above-mentioned objectives, this utility model provides the following technical solution:

[0009] A rapid reaction device for qPCR detection reagents is proposed to improve the above-mentioned problems.

[0010] The specific details of this utility model are as follows:

[0011] The device includes a housing, a temperature control component for regulating the device temperature on one side of the housing, a reagent placement component on the top of the housing, a monitoring component for monitoring the device temperature on the side wall of the housing, an auxiliary component for assisting the use of the device on one side of the housing, and a heat dissipation component at the bottom of the housing. The heat dissipation component dissipates the heat generated by the device during operation, preventing overheating from affecting the performance and lifespan of the device.

[0012] The temperature component includes an inner shell bolted to the inside of the housing, with a hot and cold air fan bolted to one end of the inner shell, and multiple sets of fins fixedly arranged inside the inner shell.

[0013] As a preferred technical solution of this utility model, the placement component includes a movable door hinged to the top of the box, a handle bolted to the movable door, a placement box embedded in the top of the box, the placement box being fixedly connected to the box by bolts, a cover plate being provided on the top of the placement box, and the placement box being located above multiple sets of fins.

[0014] As a preferred technical solution of this utility model, the monitoring component includes a temperature sensor bolted to the inner top wall of the movable door, and a touch panel bolted to the side wall of the box, the touch panel being electrically connected to the hot and cold air blower.

[0015] As a preferred technical solution of this utility model, the auxiliary component includes a switch button disposed on the side wall of the housing, a charging port disposed on one side of the switch button, and a USB port disposed on one side of the charging port. The switch button, the charging port and the USB port are all fixedly connected to the housing by bolts.

[0016] As a preferred technical solution of this utility model, the heat dissipation component includes a honeycomb vent plate bolted to the side wall of the housing. The honeycomb vent plate is located on one side of multiple sets of fins. Multiple sets of rectangular grooves are opened on one side of the housing, and the multiple sets of rectangular grooves are located on one side of the hot and cold air blower.

[0017] As a preferred technical solution of this utility model, four sets of anti-slip pads are bolted to the bottom of the box body. The four sets of anti-slip pads are evenly arranged at the four corners of the bottom of the box body, and the anti-slip pads are made of rubber.

[0018] As a preferred technical solution of this utility model, the cover plate has multiple sets of circular grooves at the position corresponding to the placement box, and the cover plate is connected to the side wall of the placement box by bolts.

[0019] Compared with the prior art, the beneficial effects of this utility model are as follows:

[0020] In the solution of this utility model:

[0021] 1. With the set temperature components, the fins, as efficient heat exchange components, can quickly absorb or release heat during use. When hot air passes through the fins, the heat is quickly transferred to the entire inner shell space, raising the temperature inside the chamber. When cold air passes through, the fins absorb the heat inside the chamber and transfer it to the cold air, thereby lowering the temperature inside the chamber. Through the cooperation of the hot and cold air blowers and the fins, the temperature regulation needs can be responded to quickly, achieving precise control of the temperature inside the chamber, meeting the needs of rapid reaction of qPCR test reagents, and improving detection efficiency.

[0022] 2. With the set placement component, when placing reagents, the operator holds the handle on the movable door to open the movable door, puts the container containing qPCR detection reagents into the placement box, and then closes the movable door to perform the test. Since the placement box is located above multiple sets of fins, the heat or cold generated by the temperature regulation of the fins can be transferred to the placement box area through air convection and other means, providing a suitable reaction temperature for the reagents in the placement box. Attached Figure Description

[0023] Figure 1 A schematic diagram of the rapid reaction device for qPCR detection reagents provided by this utility model;

[0024] Figure 2 One of the schematic diagrams of the back structure of the rapid reaction device for qPCR detection reagents provided by this utility model;

[0025] Figure 3 A second schematic diagram of the back structure of the rapid reaction device for qPCR detection reagents provided by this utility model;

[0026] Figure 4 This is a schematic diagram of the bottom structure of the rapid reaction device for qPCR detection reagents provided by this utility model;

[0027] Figure 5 One of the schematic cross-sectional views of the rapid reaction device for qPCR detection reagents provided by this utility model;

[0028] Figure 6 This is the second cross-sectional structural schematic diagram of the rapid reaction device for qPCR detection reagents provided by this utility model.

[0029] The image shows:

[0030] 1. Cabinet; 2. Temperature Components; 201. Inner Shell; 202. Hot and Cold Air Blower; 203. Fins; 3. Placement Components; 301. Door; 302. Handle; 303. Placement Box; 304. Cover Plate; 4. Monitoring Components; 401. Temperature Sensor; 402. Touch Panel; 5. Auxiliary Components; 501. Switch Button; 502. Charging Port; 503. USB Port; 6. Heat Dissipation Components; 601. Honeycomb Ventilation Panel; 602. Rectangular Groove; 7. Anti-slip Mat. Detailed Implementation

[0031] To make the objectives, technical solutions, and advantages of the embodiments of this utility model clearer, the technical solutions of the embodiments of this utility model will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some, not all, of the embodiments of this utility model.

[0032] Therefore, the following detailed description of the embodiments of this utility model is not intended to limit the scope of the claimed utility model, but merely to illustrate some embodiments of the utility model. All other embodiments obtained by those skilled in the art based on the embodiments of this utility model without inventive effort are within the scope of protection of this utility model.

[0033] It should be noted that, unless otherwise specified, the embodiments and features and technical solutions in the present invention can be combined with each other.

[0034] It should be noted that similar labels and letters in the following figures indicate similar items. Therefore, once an item is defined in one figure, it does not need to be further defined and explained in subsequent figures.

[0035] like Figure 1 and Figure 5 As shown, this embodiment proposes a rapid reaction device for qPCR detection reagents, including a housing 1. A temperature component 2 for regulating the device temperature is provided on one side of the housing 1. A placement component 3 for placing reagents is provided on the top of the housing 1. A monitoring component 4 for monitoring the device temperature is provided on the side wall of the housing 1. An auxiliary component 5 for assisting the device is provided on one side of the housing 1. A heat dissipation component 6 is provided at the bottom of the housing 1. The heat dissipation component 6 dissipates the heat generated during the operation of the device to avoid affecting the performance and lifespan of the device due to overheating.

[0036] like Figure 6As shown, the temperature component 2 includes an inner shell 201 bolted to the inside of the chamber 1. A hot / cold air blower 202 is bolted to one end of the inner shell 201. Multiple sets of fins 203 are fixedly arranged inside the inner shell 201. These fins 203 have a large surface area, allowing hot or cold air to fully contact the surface of the fins 203 as they flow between them. In use, the fins 203 act as efficient heat exchange components, rapidly absorbing or releasing heat. When hot air passes through the fins 203, heat is quickly transferred to the entire space of the inner shell 201, raising the temperature inside the chamber 1. When cold air passes through, the fins 203 absorb heat from inside the chamber 1 and transfer it to the cold air, thereby lowering the temperature inside the chamber 1. Through the cooperation of the hot / cold air blower 202 and the fins 203, the temperature adjustment needs can be quickly met, achieving precise control of the temperature inside the chamber 1, satisfying the rapid reaction requirements of qPCR reagents, and improving detection efficiency.

[0037] like Figure 5 and Figure 6 As shown, the placement assembly 3 includes a hinged door 301 hinged to the top of the housing 1, with a handle 302 bolted to the door 301. A placement box 303 is embedded in the top of the housing 1 and is fixedly connected to the housing 1 by bolts. A cover plate 304 is provided on the top of the placement box 303, which is located above multiple sets of fins 203. When placing reagents, the operator holds the handle 302 on the door 301 to open it, places the container containing the qPCR test reagent into the placement box 303, and then closes the door 301 for testing. Since the placement box 303 is located above multiple sets of fins 203, the heat or cold generated by the temperature regulation of the fins 203 can be transferred to the placement box 303 area through air convection, providing a suitable reaction temperature for the reagents inside the placement box 303.

[0038] like Figure 6 As shown, the monitoring component 4 includes a temperature sensor 401 bolted to the inner top wall of the movable door 301, and a touch panel 402 bolted to the side wall of the chamber 1. The touch panel 402 is electrically connected to the hot and cold air blower 202. The temperature sensor 401 is fixed to the inner top wall of the movable door 301. During the operation of the qPCR rapid reaction device, the temperature sensor 401 continuously monitors the temperature inside the chamber 1 and sends an electrical signal to the touch panel 402. After receiving the signal, the touch panel 402 sends a command to the hot and cold air blower 202 according to a preset program. If the detected temperature is lower than the preset lower limit, the touch panel 402 sends a command to the hot and cold air blower 202 to switch it to heating mode to regulate the temperature inside the chamber and keep it within the suitable temperature range for the qPCR reaction.

[0039] like Figure 3As shown, auxiliary component 5 includes a switch button 501 mounted on the side wall of housing 1. A charging port 502 is located on one side of the switch button 501, and a USB port 503 is located on the other side of the charging port 502. The switch button 501, charging port 502, and USB port 503 are all fixedly connected to housing 1 by bolts. Through the charging port 502, the operator can connect an external power source to charge the device. The operator can start and stop the device by pressing the operation button. Through the USB port 503, the operator can easily export experimental data to external devices for analysis.

[0040] like Figure 3 and Figure 4 As shown, the heat dissipation assembly 6 includes a honeycomb vent plate 601 bolted to the side wall of the housing 1. The honeycomb vent plate 601 is located on one side of the multiple sets of fins 203. Multiple sets of rectangular slots 602 are formed on one side of the housing 1, located on one side of the hot and cold air blower 202. The design of the multiple sets of rectangular slots 602 and the honeycomb vent plate 601 increases the airflow area and efficiency, allowing air to quickly and abundantly enter and exit the housing 1, effectively improving heat dissipation efficiency and promptly dissipating the heat generated during device operation, preventing overheating from affecting the device's performance and lifespan.

[0041] like Figure 4 As shown, four sets of anti-slip pads 7 are bolted to the bottom of the box 1. The four sets of anti-slip pads 7 are evenly distributed at the four corners of the bottom of the box 1. The anti-slip pads 7 are made of rubber. Operators can place this device on work surfaces such as desktops and test benches. The anti-slip pads 7 are in direct contact with the work surface, making it difficult to slip and easy to use.

[0042] like Figure 5 As shown, the cover plate 304 has multiple sets of circular grooves corresponding to the placement box 303, and the cover plate 304 is connected to the side wall of the placement box 303 by bolts. Through the multiple sets of circular grooves on the cover plate 304 corresponding to the placement box 303, the operator can quickly and accurately place the reagent container into the placement box 303.

[0043] Specifically, when using this qPCR rapid reaction device: (e.g.) Figure 5 and Figure 6As shown, the operator holds the handle 302 on the movable door 301 to open it, places the container containing the qPCR test reagent into the placement box 303, and then closes the movable door 301 for testing. Since the placement box 303 is located above multiple sets of fins 203, and the fins 203 act as efficient heat exchange components, they can quickly absorb or release heat. When hot air passes through the fins 203, heat is rapidly transferred to the entire inner shell 201 space, raising the temperature inside the chamber 1. When cold air passes through, the fins 203 absorb heat from inside the chamber 1 and transfer it to the cold air, thereby lowering the temperature inside the chamber 1. Through the cooperation of the hot and cold air blowers 202 and the fins 203, the temperature regulation requirements can be quickly responded to. The temperature sensor 401 is fixed to the inner top wall of the movable door 301. During the operation of the rapid reaction device for qPCR reagents, the temperature sensor 401 continuously monitors the temperature inside the chamber 1 and sends an electrical signal to the touch panel 402. After receiving the signal, the touch panel 402 sends an instruction to the hot and cold air blower 202 according to the preset program. If the detected temperature is lower than the preset lower limit, the touch panel 402 sends an instruction to the hot and cold air blower 202 to switch it to the heating mode to regulate the temperature inside the chamber and keep it within the appropriate temperature range for the qPCR reagent reaction.

[0044] All technical features in this embodiment can be freely combined according to actual needs.

[0045] The above embodiments are preferred implementations of this utility model. In addition, this utility model can also be implemented in other ways. Any obvious substitutions without departing from the concept of this technical solution are within the protection scope of this utility model.

Claims

1. A rapid reaction device for qPCR detection reagents, comprising a housing (1), characterized in that, A temperature component (2) for regulating the temperature of the device is provided on one side of the box (1), a placement component (3) for placing reagents is provided on the top of the box (1), a monitoring component (4) for monitoring the temperature of the device is provided on the side wall of the box (1), an auxiliary component (5) for assisting the device is provided on one side of the box (1), and a heat dissipation component (6) is provided at the bottom of the box (1). The temperature component (2) includes an inner shell (201) bolted to the inside of the housing (1), a hot and cold air blower (202) is bolted to one end of the inner shell (201), and multiple sets of fins (203) are fixedly arranged inside the inner shell (201).

2. The rapid reaction device for qPCR detection reagent according to claim 1, characterized in that, The placement assembly (3) includes a movable door (301) hinged to the top of the housing (1), a handle (302) is bolted to the movable door (301), a placement box (303) is embedded in the top of the housing (1), the placement box (303) is fixedly connected to the housing (1) by bolts, a cover plate (304) is provided on the top of the placement box (303), and the placement box (303) is located above multiple sets of fins (203).

3. The rapid reaction device for qPCR detection reagent according to claim 2, characterized in that, The monitoring component (4) includes a temperature sensor (401) bolted to the inner top wall of the movable door (301), and a touch panel (402) bolted to the side wall of the housing (1), which is electrically connected to the hot and cold air blower (202).

4. The rapid reaction device for qPCR detection reagent according to claim 1, characterized in that, The auxiliary component (5) includes a switch button (501) disposed on the side wall of the housing (1). A charging port (502) is disposed on one side of the switch button (501), and a USB port (503) is disposed on one side of the charging port (502). The switch button (501), the charging port (502) and the USB port (503) are all fixedly connected to the housing (1) by bolts.

5. The rapid reaction device for qPCR detection reagent according to claim 1, characterized in that, The heat dissipation assembly (6) includes a honeycomb vent plate (601) bolted to the side wall of the housing (1). The honeycomb vent plate (601) is located on one side of multiple sets of fins (203). Multiple sets of rectangular slots (602) are opened on one side of the housing (1). The multiple sets of rectangular slots (602) are located on one side of the hot and cold air blower (202).

6. The rapid reaction device for qPCR detection reagent according to claim 1, characterized in that, The bottom of the box (1) is bolted with four sets of anti-slip pads (7). The four sets of anti-slip pads (7) are evenly arranged at the four corners of the bottom of the box (1). The anti-slip pads (7) are made of rubber.

7. The rapid reaction device for qPCR detection reagent according to claim 2, characterized in that, The cover plate (304) has multiple sets of circular grooves corresponding to the position of the placement box (303), and the cover plate (304) is connected to the side wall of the placement box (303) by bolts.