A stirring device for a fermenter used in the production of antibiotic enzymes

Abstract

This application discloses a stirring device for a fermenter used in the production of antibiotic enzymes. The device includes a stirred fermenter and a stirring assembly. The stirred fermenter includes a tank body and a lid, with the lid connected to the top opening of the tank body. The stirring assembly includes stirring tubes and stirring blades. Several stirring tubes are vertically rotatably connected to the lid, with the bottom ends of the stirring tubes located within the tank body. Several stirring blades are provided on each stirring tube. A driving component for rotating the stirring tubes is provided on the lid. A first temperature sensor is provided on each stirring tube, and the first temperature sensor is electrically connected to the corresponding driving component. This application reduces the possibility of localized overheating in the fermentation device and improves the fermentation quality of the antibiotic enzymes.

Description

Technical Field

[0001] This application relates to the technical field of bio-enzyme processing, and in particular to a stirring device for a fermenter used in the production of antibiotic enzymes. Background Technology

[0002] Antibiotic enzymes, as important biological products, directly impact their downstream applications due to their production efficiency and quality. Currently, mechanically stirred fermenters are commonly used in industrial production, achieving uniform mixing of the culture medium and dissolved oxygen transfer through stirring. In recent years, with advancements in bioreactor technology, temperature control precision has become a key factor affecting enzyme activity and yield. Industry research indicates that temperature fluctuations exceeding ±1℃ can lead to a significant decrease in enzyme activity; therefore, developing stirring devices with precise temperature control capabilities has become an important research direction for improving the production efficiency of antibiotic enzymes.

[0003] Currently, when the fermentation scale of existing fermentation devices is expanded to more than 10m³, the temperature gradient phenomenon can cause local overheating, resulting in an enzyme activity loss rate of 20-30%, which affects the normal fermentation process. Utility Model Content

[0004] In order to reduce the possibility of local overheating in the fermentation device and improve the fermentation quality of antibiotic enzymes, this application provides a fermentation tank stirring device for antibiotic enzyme production.

[0005] The stirring device for a fermenter used in the production of antibiotic enzymes provided in this application adopts the following technical solution:

[0006] A stirring device for a fermenter used in the production of antibiotic enzymes includes a stirred fermenter and a stirring assembly. The stirred fermenter includes a tank body and a tank cover. The tank cover is connected to the top opening of the tank body. The stirring assembly includes stirring tubes and stirring blades. Several stirring tubes are vertically rotatably connected to the tank cover. The bottom end of each stirring tube is located in the tank body. Several stirring blades are provided on each stirring tube. A driving component for driving the stirring tubes to rotate is provided on the tank cover. A first temperature sensor is provided on each stirring tube. The first temperature sensor is electrically connected to the corresponding driving component.

[0007] By adopting the above technical solution, the first temperature sensor detects the ambient temperature near each stirring tube. When the temperature near a certain stirring rod is too high, the drive component connected to it drives the stirring rod to increase its rotation speed. The stirring blades on it accelerate the stirring of the material, which helps to cool down and dissipate heat, reducing the possibility of local overheating. Through the cooperation of the stirred fermentation tank and the stirring components, the possibility of local overheating in the fermentation device is reduced, and the fermentation quality of the antibiotic enzymes is improved.

[0008] Optionally, the stirred fermentation tank is equipped with a cooling component, which includes a cooling water tank, a water supply pipe, a water outlet pipe, a water supply pump, and a water outlet pump. The stirring tube is hollow, with its bottom end closed. A partition plate is vertically installed inside the stirring tube, with its bottom end spaced apart from the bottom end of the stirring tube. The partition plate divides the inner cavity of the stirring tube into an inlet chamber and an outlet chamber. The top end of the outlet chamber is closed, and an outlet is provided on the peripheral wall of the top end of the stirring tube, communicating with the outlet chamber. The top end of the stirring tube is rotatably connected to an inlet sleeve via a sealed bearing. The inlet sleeve is connected to the water inlet chamber. A discharge sleeve is rotatably fitted onto the stirring tube via a sealed bearing. The discharge sleeve is connected to the water outlet chamber via the water outlet. The inlet sleeve is connected to the water supply pipe. The other end of the water supply pipe is connected to the cooling water tank. The discharge sleeve is connected to the water outlet pipe. The other end of the water outlet pipe is connected to the cooling water tank. A water pump is installed on the water supply pipe. The water pump is installed on the water outlet pipe.

[0009] By adopting the above technical solution, when the temperature near a certain stirring tube becomes too high, the corresponding water pump and outlet pump are activated. Cooling water from the cooling water tank enters the inlet chamber of the stirring tube through the water supply pipe and the inlet sleeve. The cooling water in the inlet chamber flows into the outlet chamber and then into the outlet sleeve through the outlet. The water in the outlet sleeve flows back to the cooling water tank through the outlet pipe for further cooling. The cooling water in the stirring tube cools the materials nearby, which helps to improve the cooling effect on the surrounding materials.

[0010] Optionally, the stirring blade is hollow, and a connecting sleeve is connected to the side of the stirring blade near the stirring tube. One end of the connecting sleeve is connected to the inner cavity of the stirring blade, and the other end is connected to the inner cavity of the stirring tube.

[0011] By adopting the above technical solution, cooling water enters the inner cavity of the stirring blade, which expands the contact area between the cooling water and the material, and helps to further improve the cooling effect on the material.

[0012] Optionally, the stirring tube is provided with a plurality of mounting tubes, and the plurality of mounting tubes are provided and rotatably connected to the plurality of connecting sleeves in a one-to-one correspondence.

[0013] By adopting the above technical solution, the angle between the stirring blade and the stirring tube can be adjusted. This allows operators to easily adjust the angle of the stirring blade to meet different stirring needs.

[0014] Optionally, a sealing ring is provided on the outer ring wall of the mounting tube, and the connecting sleeve is fitted onto the corresponding mounting tube.

[0015] By adopting the above technical solution, the sealing ring improves the sealing performance between the connecting sleeve and the installation pipe, which helps to reduce the possibility of cooling water leakage.

[0016] Optionally, the end of the connecting sleeve away from the stirring plate is provided with a plurality of connecting grooves, and a connecting clamp is provided at the position where the connecting grooves are provided on the outside of the connecting sleeve.

[0017] By adopting the above technical solution, the connecting sleeve is fitted onto the installation pipe and adjusted to a suitable angle. The connecting sleeve is then tightened onto the installation pipe using connecting clamps, thus achieving a stable connection between the installation pipe and the connecting sleeve.

[0018] Optionally, a stirring arc rod is provided at the inner bottom of the tank along its radial direction, and a driving component for driving the stirring arc rod to rotate is provided on the tank body. Several stirring rods are vertically connected to the stirring arc rod.

[0019] By adopting the above technical solution, the stirring rod and the stirring bar set on it stir the material at the bottom of the tank, which helps to improve the uniformity of material distribution in the tank.

[0020] Optionally, two cooling jackets are fitted on the outside of the tank body along the vertical direction, and two second temperature sensors are connected to the inner wall of the tank body. The two second temperature sensors and the two cooling jackets are arranged in a one-to-one correspondence in height, and the second temperature sensors are electrically connected to the corresponding cooling jackets.

[0021] By adopting the above technical solution, two second temperature sensors detect the temperature at the top and bottom of the tank. When the local temperature is too high, the corresponding cooling jacket is activated to cool the tank, which helps to improve the temperature uniformity inside the tank.

[0022] In summary, this application includes at least one of the following beneficial technical effects:

[0023] 1. By cooperating with the stirred fermenter and the stirring components, the possibility of local overheating in the fermentation device is reduced, and the fermentation quality of the antibiotic enzymes is improved.

[0024] 2. The installation of a second temperature sensor and a cooling jacket helps to improve the temperature uniformity inside the tank;

[0025] 3. The installation tube design allows for adjustable angle between the stirring blades and the stirring tube. This facilitates operators in adjusting the angle of the stirring blades to meet different stirring needs. Attached Figure Description

[0026] Figure 1This is a schematic diagram illustrating the structure of a stirring device for a fermenter used in the production of antibiotic enzymes, as described in this application.

[0027] Figure 2 This is a partial cross-sectional view used in the embodiments of this application to illustrate the internal structure of the stirred fermenter.

[0028] Figure 3 yes Figure 2 Enlarged view of part A in the middle.

[0029] Figure 4 yes Figure 2 Enlarged view of section B in the middle.

[0030] Explanation of reference numerals in the attached drawings: 1. Stirred fermentation tank; 101. Tank body; 102. Tank lid; 103. Feed pipe; 2. Stirring assembly; 201. Stirring pipe; 2011. Water outlet; 202. Divider plate; 203. Stirring blade; 204. Connecting sleeve; 2041. Connecting groove; 205. Mounting pipe; 206. Sealing ring; 207. Connecting clamp; 208. Stirring motor; 209. Drive gear; 210. Driven gear ring; 211. Drive motor; 212. Stirring arc rod; 213. Stirring rod; 3. Cooling assembly; 301. Feed sleeve; 302. Discharge sleeve; 303. Water supply pipe; 304. Water outlet pipe; 305. Cooling water tank; 306. Water pump; 307. Water pump; 308. First temperature sensor; 309. Cooling jacket; 310. Second temperature sensor. Detailed Implementation

[0031] The following is in conjunction with the appendix Figure 1-4 This application will be further described in detail below. Embodiments of this application provide a stirring device for a fermenter used in the production of antibiotic enzymes, which reduces the possibility of localized overheating in the fermentation device and improves the fermentation quality of the antibiotic enzymes.

[0032] Reference Figure 1 and Figure 2 A fermentation tank stirring device for producing antibiotic enzymes includes a stirred fermentation tank 1, a stirring assembly 2, and a cooling assembly 3. The stirred fermentation tank 1 includes a tank body 101 and a tank cover 102. The top of the tank body 101 is open, and the tank cover 102 is disposed at the top opening of the tank body 101.

[0033] Reference Figure 2-4The stirring assembly 2 is installed on the stirred fermentation tank 1. The stirring assembly 2 includes stirring tubes 201, partition plates 202, stirring blades 203, connecting sleeves 204, mounting pipes 205, sealing rings 206, connecting clamps 207, stirring motors 208, drive gears 209, driven gear rings 210, drive motors 211, stirring arc rods 212, and stirring rods 213. Several stirring tubes 201 rotate vertically on the tank cover 102, with open tops and closed bottoms. Several stirring motors 208 are installed on the tank cover 102, each corresponding to one stirring tube 201. The drive gears 209 are connected to the stirring motors 208. Each stirring tube 201 is connected to a corresponding drive gear 209, which meshes with the corresponding driven gear ring 210. A partition plate 202 is vertically disposed within the stirring tube 201, dividing the stirring tube 201 into an inlet chamber and an outlet chamber. The bottom end of the partition plate 202 is spaced apart from the inner bottom wall of the stirring tube 201, and the top end of the outlet chamber is closed. An outlet 2011 communicating with the outlet chamber is provided on the peripheral wall at the top end of the stirring tube 201.

[0034] Reference Figure 2-4 Several stirring blades 203 are provided on the stirring tube 201. The inner cavity of the stirring blade 203 is hollow. A connecting sleeve 204 is provided at the end of the stirring blade 203 near the stirring tube 201. Several mounting tubes 205 are provided on the stirring tube 201. A sealing ring 206 is sleeved on the outside of the mounting tube 205. Several mounting tubes 205 are provided in a one-to-one correspondence with several connecting sleeves 204, and the connecting sleeves 204 are sleeved on the corresponding mounting tubes 205. Several connecting grooves 2041 are provided at the end of the connecting sleeve 204 away from the stirring blade 203. A connecting clamp 207 for fixing is provided on the outside of the connecting sleeve 204 with the connecting grooves 2041. Two stirring arc rods 212 are provided at the inner bottom of the tank body 101. The stirring arc rods 212 are arranged along the diameter direction of the tank body 101. Several stirring rods 213 are vertically connected to the stirring arc rods 212. The drive motor 211 is located at the bottom of the tank body 101, and the output shaft of the drive motor 211 is connected to the connection of the two stirring rods 212.

[0035] Reference Figure 1-3The cooling assembly 3 includes an inlet sleeve 301, an outlet sleeve 302, a water supply pipe 303, an outlet pipe 304, a cooling water tank 305, a water supply pump 306, an outlet pump 307, a first temperature sensor 308, a cooling jacket 309, and a second temperature sensor 310. The inlet sleeve 301 is rotatably connected to the top of the stirring tube 201 via a sealed bearing. The inlet sleeve 301 is connected to the water inlet chamber. One end of the water supply pipe 303 is connected to the inlet sleeve 301, and the other end is connected to the cooling water tank 305. The water supply pump 306 is connected to the water supply pipe 303. The outlet sleeve 302 is rotatably connected to the stirring tube 201 via a sealed bearing. The inner cavity of the outlet sleeve 302 is connected to the outlet chamber via a water outlet 2011. One end of the water outlet pipe 304 is connected to the discharge sleeve 302, and the other end is connected to the cooling water tank 305. The water outlet pump 307 is connected to the water outlet pipe 304.

[0036] Reference Figure 1 and Figure 2 One first temperature sensor 308 is provided on each stirring tube 201, and the first temperature sensor 308 is electrically connected to the corresponding stirring motor 208, water pump 307, and water pump 306. Two cooling jackets 309 are fitted vertically on the outside of the tank body 101, and two second temperature sensors 310 are connected to the inner wall of the tank body 101. The two second temperature sensors 310 and the two cooling jackets 309 correspond one-to-one in height and are electrically connected.

[0037] Reference Figure 2 and Figure 3 During fermentation and stirring of the materials, the stirring motor 208 starts, driving the drive gear 209 to rotate. The driven gear ring 210 and the corresponding stirring tube 201 rotate under the drive. The stirring blades 203 on the stirring tube 201 stir the materials in the tank 101. Several first temperature sensors 308 detect the temperature of the materials around the stirring tube 201. When the temperature near a certain stirring tube 201 is too high, the speed of the corresponding stirring motor 208 increases, which helps to cool down the materials. At the same time, the corresponding water pump 306 and water pump 307 start. Cooling water enters the feed sleeve 301 through the water supply pipe 303. The cooling water flows through the water inlet chamber, the water outlet chamber, and the inner cavity of the stirring blades 203 in sequence, cooling the surrounding materials. Finally, it flows back to the cooling water tank 305 through the discharge sleeve 302 and the water outlet pipe 304 for further cooling and recycling.

[0038] Reference Figure 1 , Figure 3 and Figure 4The connection sleeve 204 and the mounting pipe 205 allow for adjustable angle of the stirring blade 203, while the sealing ring 206 improves the seal between them. The connection groove 2041 and the connecting clamp 207 facilitate the operator in fixing the mounting pipe 205 to the connection sleeve 204. The second temperature sensor 310 detects the material temperature at both the upper and lower positions. When local overheating occurs, the corresponding cooling jacket 309 precisely cools the tank body 101. Simultaneously, the drive motor 211 starts, driving the stirring rod and stirring bar 213 to rotate, achieving uniform stirring of the material at the bottom of the tank body 101, further reducing the possibility of local overheating.

[0039] The implementation principle of the fermentation tank stirring device for antibiotic enzyme production in this embodiment is as follows: During fermentation and stirring of materials, the stirring blade 203 stirs the materials in the tank body 101. Several first temperature sensors 308 detect the temperature of the materials around the stirring tube 201. When the temperature near a certain stirring tube 201 is too high, the speed of the corresponding stirring motor 208 increases. At the same time, the corresponding water pump 306 and water outlet pump 307 are started, and cooling water flows sequentially through the water inlet chamber, water outlet chamber, and the inner cavity of the stirring blade 203 to cool the surrounding materials. Finally, it flows back to the cooling water tank 305 for further cooling and recycling through the discharge sleeve and water outlet pipe 304. The second temperature sensor 310 detects the temperature of the materials at two positions, above and below. When local overheating occurs, the corresponding cooling jacket 309 precisely cools the tank body 101.

[0040] The above are all preferred embodiments of this application, and are not intended to limit the scope of protection of this application. Therefore, all equivalent changes made in accordance with the structure, shape and principle of this application should be covered within the scope of protection of this application.

Claims

1. A stirring device for a fermenter used in the production of antibiotic enzymes, characterized in that: The mixture includes a stirred fermentation tank (1) and a stirring assembly (2). The stirred fermentation tank (1) includes a tank body (101) and a tank cover (102). The tank cover (102) is connected to the top opening of the tank body (101). The stirring assembly (2) includes a stirring tube (201) and stirring blades (203). Several stirring tubes (201) are vertically rotatably connected to the tank cover (102). The bottom end of the stirring tube (201) is located in the tank body (101). Several stirring blades (203) are provided on each stirring tube (201). A driving component for driving the stirring tube (201) to rotate is provided on the tank cover (102). A first temperature sensor (308) is provided on the stirring tube (201). The first temperature sensor (308) is electrically connected to the corresponding driving component.

2. The stirring device for a fermenter used in the production of antibiotic enzymes according to claim 1, characterized in that: The stirred fermentation tank (1) is equipped with a cooling component (3), which includes a cooling water tank (305), a water supply pipe (303), a water outlet pipe (304), a water supply pump (306), and a water outlet pump (307). The stirring tube (201) is hollow, and the bottom end of the stirring tube (201) is closed. A partition plate (202) is vertically arranged in the stirring tube (201), and the bottom end of the partition plate (202) is spaced apart from the bottom end of the stirring tube (201). The partition plate (202) divides the inner cavity of the stirring tube (201) into an inlet cavity and an outlet cavity. The top end of the outlet cavity is closed. An outlet (2011) is opened on the peripheral wall of the top end of the stirring tube (201), and the outlet (2011) is connected to the outlet cavity. The top of the stirring tube (201) is rotatably connected to the feed sleeve (301) via a sealed bearing. The feed sleeve (301) is connected to the water inlet chamber. The stirring tube (201) is rotatably fitted with a discharge sleeve (302) via a sealed bearing. The discharge sleeve (302) is connected to the water outlet chamber via the water outlet (2011). The feed sleeve (301) is connected to the water supply pipe (303). The other end of the water supply pipe (303) is connected to the cooling water tank (305). The discharge sleeve (302) is connected to the water outlet pipe (304). The other end of the water outlet pipe (304) is connected to the cooling water tank (305). The water supply pump (306) is installed on the water supply pipe (303). The water outlet pump (307) is installed on the water outlet pipe (304).

3. The stirring device for a fermenter used in the production of antibiotic enzymes according to claim 2, characterized in that: The stirring blade (203) is hollow, and a connecting sleeve (204) is connected to the side of the stirring blade (203) near the stirring tube (201). One end of the connecting sleeve (204) is connected to the inner cavity of the stirring blade (203), and the other end is connected to the inner cavity of the stirring tube (201).

4. The stirring device for a fermenter used in the production of antibiotic enzymes according to claim 3, characterized in that: The stirring tube (201) is connected to a plurality of mounting tubes (205), and the plurality of mounting tubes (205) are correspondingly and rotatably connected to the plurality of connecting sleeves (204).

5. The stirring device for a fermenter used in the production of antibiotic enzymes according to claim 4, characterized in that: A sealing ring (206) is provided on the outer ring wall of the mounting tube (205), and the connecting sleeve (204) is sleeved on the corresponding mounting tube (205).

6. The stirring device for a fermenter used in the production of antibiotic enzymes according to claim 5, characterized in that: The connecting sleeve (204) has a plurality of connecting grooves (2041) at one end away from the stirring plate (203), and a connecting clamp (207) is provided at the position where the connecting grooves (2041) are provided on the outside of the connecting sleeve (204).

7. The stirring device for a fermenter used in the production of antibiotic enzymes according to claim 1, characterized in that: A stirring arc rod (212) is provided on the inner bottom of the tank body (101) along its radial direction. A driving component for driving the stirring arc rod (212) to rotate is provided on the tank body (101). Several stirring rods (213) are vertically connected to the stirring arc rod (212).

8. The stirring device for a fermenter used in the production of antibiotic enzymes according to claim 1, characterized in that: Two cooling jackets (309) are fitted on the outside of the tank body (101) along the vertical direction. Two second temperature sensors (310) are connected to the inner wall of the tank body (101). The two second temperature sensors (310) and the two cooling jackets (309) are arranged in a one-to-one correspondence in height. The second temperature sensors (310) are electrically connected to the corresponding cooling jackets (309).

Images