An auxiliary device for sputtering and membrane drawing of a sputtering membrane drawing instrument
By designing an auxiliary device for the gold spraying film scribing instrument, using a weight ball and a nuclear pore membrane to filter air bubbles, and adjusting the position of the scribing needle in conjunction with the scale lines on the support, the problems of uneven gold spraying and scribing accuracy were solved, thereby improving the uniformity of gold spraying and the accuracy of scribing, and enhancing the detection accuracy and quality of the test strips.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- JIANGSU FANBO BIOLOGICAL PROD CO LTD
- Filing Date
- 2025-06-12
- Publication Date
- 2026-06-02
AI Technical Summary
Existing gold spraying scribing instruments are prone to introducing air bubbles during gold spraying and sample loading, resulting in uneven spraying of colloidal gold strips. Furthermore, the height of the scribing needle is difficult to adjust precisely, leading to batch-to-batch differences in test strips and damage to the NC membrane.
An auxiliary device was designed, comprising a support, a solution inlet tube, a sample loading control cap, a filter, a centrifuge tube, and a steel needle insertion tube. It utilizes a weighted ball and a nuclear pore membrane filter to filter air bubbles, and the scale lines on the support assist in adjusting the position of the scribing needle to ensure uniform gold spraying and scribing accuracy.
It effectively filters out air bubbles and impurities in the colloidal gold solution, ensuring that the sprayed colloidal gold strips are uniform, reducing batch-to-batch variation of test strips, improving the accuracy of test results, and avoiding damage to the NC membrane.
Smart Images

Figure CN224308713U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the technical field of chromatography test strip production equipment, specifically an auxiliary device for gold spraying sample loading and film application in a gold spraying film application instrument. Background Technology
[0002] The gold spraying and scrubbing apparatus is a key piece of equipment in the production of large-scale chromatographic test strips. Its gold spraying function is used to uniformly spray colloidal gold solution onto glass fiber material, while the scrubbing function is used to form a detection line on the NC membrane. However, existing gold spraying and scrubbing apparatuses have problems such as the easy incorporation of air bubbles during sample loading and the difficulty in accurately adjusting the scrubbing needle height. For example, during sample loading, the experimenter needs to manually fix the aspiration tube in the colloidal gold solution. Improper operation can easily cause air bubbles to be drawn in with the solution, resulting in uneven sprayed colloidal gold strips, causing batch-to-batch differences in test strips and increasing experimental data errors. During scrubbing, the adjustment of the distance between the scrubbing needle and the operating table requires high precision. If the distance is too high, the coating solution will form droplets on the NC membrane, failing to form a uniform straight line. If the distance is too low, it will scratch the NC membrane or even break the large-plate NC membrane, resulting in cost waste and false positives on the test strips.
[0003] Therefore, there is an urgent need to develop an auxiliary device that integrates precision filtration and positioning support to improve the uniformity of gold spraying and the accuracy of film application. Utility Model Content
[0004] To solve the above-mentioned technical problems, the present invention adopts the following technical solution:
[0005] An auxiliary device for gold spraying and film application in a gold spraying and film application instrument includes a support, a solution inlet tube, a sample control cap, a filter, a centrifuge tube, and a steel needle insertion tube. The support has a C-line, a quantitative T-line, and a qualitative T-line on its bottom side, and a height positioning line on one side of the support. A weight ball is fixedly connected to the inlet end of the solution inlet tube, and the outlet end passes through the sample control cap and the filter in sequence before being connected to the steel needle insertion tube. The solution inlet tube, the filter, and the steel needle insertion tube are interconnected. A through hole is provided inside the weight ball, and the through hole is connected to the inlet end of the solution inlet tube.
[0006] Before applying the gold sputtering membrane, the researchers placed the auxiliary device on the operating table of the gold sputtering membrane applicator and adjusted the left-right and height positions of the applicator needle according to the scale lines on the stand. This ensured accurate C and T lines were drawn on the NC membrane, guaranteeing the detection performance and accuracy of the test strip. A weighted ball was used to ensure the solution aspiration tube remained submerged below the solution surface, facilitating the extraction of all colloidal gold solution. A filtration device was also incorporated to effectively filter impurities and air bubbles from the colloidal gold solution, resulting in a uniform colloidal gold strip.
[0007] Furthermore, the bracket and the sample control cover are integrally injection molded, and the material is plastic.
[0008] The above technical solution allows centrifuge tubes to be placed stably on the support, freeing up manpower and preventing air bubbles from being drawn in during sample loading.
[0009] Furthermore, the sample control cover has a through hole at its center, and a sealing ring is fixed around the through hole by adhesive.
[0010] With the above technical solution, the solution inlet tube can smoothly pass through the sample control cover to reach the inside of the centrifuge tube. A sealing ring is set around the through hole of the cover to seal the connection with the solution inlet tube, preventing the colloidal gold solution inside the centrifuge tube from overflowing and preventing air leakage during the negative pressure inlet process from disrupting the fluid continuity.
[0011] Furthermore, the sample loading control cover has an annular protrusion on the side facing the centrifuge tube, the outer wall of the annular protrusion has an external thread, and the centrifuge tube opening has an internal thread that matches the external thread of the outer wall of the annular protrusion. The annular protrusion is threadedly connected to the centrifuge tube.
[0012] The above technical solution can securely fix centrifuge tubes to the bracket, making it convenient for experimenters to install and remove centrifuge tubes, and also making it convenient for experimenters to change colloidal gold solution.
[0013] Furthermore, a groove is formed around the bottom of the annular protrusion near the sample control cover, and an O-ring is embedded in the groove.
[0014] Through the above technical solution, the sample control cap and centrifuge tube are sealed together to prevent colloidal gold solution from seeping out from the thread gap, and also to prevent air leakage during the negative pressure suction process from disrupting the fluid continuity.
[0015] Furthermore, the filtration device includes an upper cover, a lower cover, and a filter membrane. The lower cover is integrally injection molded and connected to the solution suction tube, and the upper cover is integrally injection molded and connected to the steel needle insertion tube. A filter membrane is sandwiched between the upper cover and the lower cover.
[0016] The above technical solution can effectively filter impurities and bubbles in colloidal gold solution and spray out uniform colloidal gold strips.
[0017] Furthermore, the upper cover and the lower cover are bonded and sealed together using adhesive.
[0018] The above technical solutions prevent colloidal gold solution from seeping out of the gaps and also prevent air leakage during the negative pressure suction process from disrupting fluid continuity.
[0019] Furthermore, the filter membrane is a nuclear pore membrane.
[0020] The above technical solution utilizes nuclear pore membranes with pore sizes of 0.1-1 μm, which are smaller than the typical size of bubbles in colloidal gold solutions (greater than 10 μm). This allows for filtration by trapping bubbles. Furthermore, the nuclear pore membranes have uniform pore size, smooth surfaces, high filtration speed, and good trapping characteristics. They also exhibit good chemical and thermal stability, as well as good biological properties, effectively filtering impurities and bubbles from colloidal gold solutions.
[0021] Furthermore, the solution suction tube, upper cover, lower cover, weight ball, and steel needle insertion tube are made of plastic.
[0022] The above technical solution allows researchers to easily pass the solution aspiration tube through the sample control cap and pull the solution aspiration tube so that the weight ball can reach the inside of the centrifuge tube.
[0023] Furthermore, the inlet end of the solution suction tube is sealed to the weight ball by adhesive.
[0024] Through the above technical solution, the weight ball can be firmly fixed at the liquid inlet end of the solution suction tube.
[0025] The beneficial effects of this utility model are:
[0026] The auxiliary device for gold spraying and coating of this invention uses a nuclear pore membrane as a filter membrane, which can effectively filter out air bubbles and tiny impurities in the gold solution, ensuring that the sprayed colloidal gold strip is uniform, thereby reducing the batch-to-batch variation of the test strip and improving the accuracy of the test results.
[0027] The holder is equipped with a C-line, a qualitative T-line, a quantitative T-line, and a height positioning line, which allows experimenters to set the position of the scribing needle according to the position of the scale line, avoid damage to the NC membrane or uneven lines caused by improper scribing needle height, and ensure accurate scribing of the C-line and T-line, thereby improving the quality of the test strip. Attached Figure Description
[0028] The following explains the contents of the accompanying drawings and the markings in the drawings:
[0029] Figure 1 This is an overall schematic diagram of the auxiliary device for gold spraying and coating of a gold spraying and coating instrument according to the present invention.
[0030] Figure 2 This is a schematic diagram of the reverse side of the sample loading control cover of the auxiliary device for gold spraying and film coating of the present invention.
[0031] In the diagram: 1. Support; 11. C-line; 12. Quantitative T-line; 13. Qualitative T-line; 14. Height positioning line; 2. Solution aspiration tube; 21. Weight ball; 3. Sample loading control cap; 31. Top cap through hole; 32. Top cap sealing ring; 33. Annular protrusion; 34. Groove; 35. O-ring seal; 4. Filter device; 41. Upper cover; 42. Lower cover; 43. Filter membrane; 5. Centrifuge tube; 6. Steel needle insertion tube. Detailed Implementation
[0032] The present invention will now be described in detail with reference to the accompanying drawings.
[0033] like Figure 1 As shown, this utility model provides an auxiliary device for gold spraying and film application in a gold spraying and film application instrument. It includes a support 1, a solution inlet tube 2, a sample control cover 3, a filter device 4, a centrifuge tube 5, and a steel needle insertion tube 6. The support 1 has a C-line 11, a quantitative T-line 12, and a qualitative T-line 13 engraved on its bottom side. A height positioning line 14 is engraved on one side of the support 1. A weight ball 21 is fixedly connected to the inlet end of the solution inlet tube 2. The outlet end passes through the sample control cover 3 and the filter device 4 in sequence and is connected to the steel needle insertion tube 6. The solution inlet tube 2, the filter device 4, and the steel needle insertion tube 6 are interconnected. A through hole is provided inside the weight ball 21, which communicates with the inlet end of the solution inlet tube 2. The support 1 and the sample control cover 3 are integrally injection molded from plastic. The sample control cover 3 has a top cover through hole 31 at its center, and a top cover sealing ring 32 is fixed around the top cover through hole 31 by adhesive.
[0034] like Figure 2 As shown, the sample loading control cover 3 has an annular protrusion 33 on the side facing the centrifuge tube 5. The outer wall of the annular protrusion 33 has an external thread, and the centrifuge tube 5 has an internal thread at the tube opening that matches the external thread of the annular protrusion 33. The annular protrusion 33 is threadedly connected to the centrifuge tube 5. A groove 34 is formed around the bottom of the annular protrusion 33 near the sample loading control cover 3, and an O-ring seal 35 is embedded in the groove 34.
[0035] like Figure 1 As shown, the filtration device 4 includes an upper cover 41, a lower cover 42, and a filter membrane 43. The lower cover 42 is integrally injection molded and fixedly connected to the liquid outlet end of the solution inlet pipe 2, and the internal flow channels of the two are seamlessly connected to ensure that the solution is transmitted without leakage. The upper cover 41 is integrally injection molded and fixedly connected to the steel needle insertion pipe 6, and the internal flow channels of the two are seamlessly connected to ensure that the solution is transmitted without leakage. The filter membrane 43 is sandwiched between the upper cover 41 and the lower cover 42. The upper cover 41 and the lower cover 42 are bonded and sealed together with adhesive. The filter membrane 43 is a nuclear pore membrane.
[0036] Among them, the solution suction tube 2, the upper cover 41, the lower cover 42, the weight ball 21 and the steel needle insertion tube 6 are made of plastic, and the liquid inlet end of the solution suction tube 2 is bonded and sealed to the weight ball 21 with adhesive.
[0037] When using this invention, the experimenter places the auxiliary device on the operating table of the gold spraying film scribing instrument and adjusts the left and right positions and height of the scribing needle according to the scale lines on the bracket 1 to ensure that the gold spraying film scribing instrument scribing accurately scribes C-lines and T-lines.
[0038] The specific working principle is as follows:
[0039] Solution aspiration: Place the colloidal gold solution in centrifuge tube 5, pass the solution aspiration tube 2 of the auxiliary device through the through hole in the center of the sample control cap 3 and pull it so that the weight ball 21 is 1-2 mm away from the bottom of the centrifuge tube 5. Then connect the centrifuge tube 5 tightly to the sample control cap 3 through the threaded connection. The weight ball 21 keeps the solution aspiration tube 2 submerged below the solution surface, which facilitates the aspiration of all colloidal gold solution. Under negative pressure, the colloidal gold solution enters the solution aspiration tube 2 through the through hole of the weight ball 21.
[0040] Filtering air bubbles: The solution in the solution aspiration tube 2 passes through the sample control cover 3 and the filter device 4 in sequence, and finally enters the steel needle insertion tube 6. The filter membrane 43 in the filter device 4 can filter out air bubbles and impurities in the colloidal gold solution, ensuring that the sprayed colloidal gold strip is uniform and reducing batch-to-batch differences and experimental errors.
[0041] Spraying gold or sliding film: After the sample loading is completed, the experimenter connects the steel needle to the spraying port of the spraying gold scrubbing instrument, removes the auxiliary device and starts the spraying gold operation. Before sliding film, the experimenter puts the auxiliary device back on the operating table of the spraying gold scrubbing instrument, and adjusts the left and right and height positions of the scrubbing needle according to the C line and T line positions on the bracket 1, and finally completes the scrubbing operation.
[0042] The above description is only a preferred embodiment of the present utility model. It should be noted that for those skilled in the art, several improvements can be made without departing from the principle of the present utility model, and these improvements should also be considered within the protection scope of the present utility model.
Claims
1. An auxiliary device for gold spraying and coating in a gold spraying and coating instrument, characterized in that: The device includes a support (1), a solution inlet tube (2), a sample loading control cap (3), a filter (4), a centrifuge tube (5), and a steel needle insertion tube (6). The support (1) has a C-line (11), a quantitative T-line (12), and a qualitative T-line (13) on its bottom side. The support (1) has a height positioning line (14) on one side. The inlet end of the solution inlet tube (2) is fixedly connected to a weight ball (21). The outlet end passes through the sample loading control cap (3) and the filter (4) in sequence and is connected to the steel needle insertion tube (6). The three are interconnected. The weight ball (21) has a through hole inside, which is connected to the inlet end of the solution inlet tube (2).
2. The auxiliary device for gold spraying and coating of a gold spraying and coating instrument according to claim 1, characterized in that: The bracket (1) and the sample control cover (3) are integrally injection molded and the material is plastic.
3. The auxiliary device for gold spraying and coating of a gold spraying and coating instrument according to claim 1, characterized in that: The sample control cover (3) has a cover through hole (31) at the center, and a cover sealing ring (32) is glued around the cover through hole (31).
4. The auxiliary device for gold spraying and coating of a gold spraying and coating instrument according to claim 1, characterized in that: The sample control cover (3) has a threaded annular protrusion (33) on the side facing the centrifuge tube (5). The centrifuge tube (5) has an internal thread at the opening that matches the external thread of the annular protrusion (33). The annular protrusion (33) is threadedly connected to the centrifuge tube (5).
5. The auxiliary device for gold spraying and coating of a gold spraying and coating instrument according to claim 4, characterized in that: The annular protrusion (33) has a groove (34) around the bottom of the sample control cover, and an O-ring (35) is embedded in the groove (34).
6. The auxiliary device for gold spraying and coating of a gold spraying and coating instrument according to claim 1, characterized in that: The filtration device (4) includes an upper cover (41), a lower cover (42) and a filter membrane (43). The lower cover (42) is integrally injection molded and connected to the solution suction tube (2). The upper cover (41) is integrally injection molded and connected to the steel needle insertion tube (6). The filter membrane (43) is sandwiched between the upper cover (41) and the lower cover (42).
7. The auxiliary device for gold spraying and coating of a gold spraying and coating instrument according to claim 6, characterized in that: The upper cover (41) and the lower cover (42) are bonded and sealed together with adhesive.
8. The auxiliary device for gold spraying and coating of a gold spraying and coating instrument according to claim 6, characterized in that: The filter membrane (43) is a nuclear pore membrane.
9. The auxiliary device for gold spraying and coating of a gold spraying and coating instrument according to claim 6, characterized in that: The solution suction tube (2), upper cover (41), lower cover (42), weight ball (21) and steel needle insertion tube (6) are made of plastic.
10. The auxiliary device for gold spraying and coating of a gold spraying and coating instrument according to claim 1, characterized in that: The solution inlet tube (2) is sealed to the weight ball (21) by adhesive.