Tumor electric field treatment device

Abstract

The application relates to the technical field of tumor electric field treatment, and discloses a tumor electric field treatment device, which comprises an electrode patch, an electric field generating device, a plurality of power supply devices and a power supply switching circuit. The electric field generating device is suitable for generating an alternating electric signal, wherein the alternating electric signal is applied to the electrode patch to apply an alternating electric field to a tumor part of a human body; each of the plurality of power supply devices is suitable for supplying power to the electric field generating device; and the power supply switching circuit is configured to communicate a power supply path between one of the plurality of power supply devices and the electric field generating device based on a power supply voltage of each power supply device, so that the plurality of power supply devices seamlessly switch to supply power to the electric field generating device, power supply is ensured not to be interrupted, the effective treatment electric field duration of the tumor electric field treatment instrument applied to a tissue region where a tumor is located is improved, and the treatment effect is improved.

Description

Technical Field

[0001] This application relates to the field of tumor electric field therapy technology, and more particularly to a tumor electric field therapy device. Background Technology

[0002] Using electric fields to treat tumors is currently at the forefront of research. Tumor treating fields (TTF) is a method that applies low-intensity, medium-frequency alternating electric fields to cancer cells, thereby interfering with the process of cell mitosis, inhibiting cancer cell mitosis, and inducing apoptosis, thus treating tumors or cancers. Studies have shown that electric field therapy is effective in treating diseases such as glioblastoma, non-small cell lung cancer, and malignant pleural mesothelioma. The electric field applied by this method can affect the aggregation of microtubules in dividing cancer cells, prevent the formation of spindle fibers in dividing cancer cells, inhibit the process of cancer cell mitosis, and induce apoptosis in cancer cells.

[0003] In related technologies, tumor electric field therapy (TEF) devices for tumor treatment mainly include a TTF device and electrode patches electrically connected to it. Generally, the electrode patches are applied to the skin corresponding to the lesion, thereby applying alternating electrical signals to the tumor tissue area for electric field therapy. TTF devices typically use either battery power or adapter power. When the user is not active, adapter power is recommended; when the user is active or outdoors, battery power is recommended. When switching to battery power is necessary due to unexpected adapter power failure, outdoor activities, or low battery power, a power mode switch is required. During this switch, the TTF device will temporarily interrupt power supply until the switch is complete. After the switch, an initialization process is required to restart the device before electric field therapy can resume. Studies have shown that the therapeutic effect of tumor treatment using electric fields is related to the duration of the effective therapeutic electric field applied to the tumor tissue area; the longer the duration, the better the therapeutic effect. The current switching between battery power and adapter power will interrupt the electric field therapy, shorten the duration of the electric field therapy, and thus reduce the therapeutic effect. Utility Model Content

[0004] This application provides a tumor electric field therapy device that solves the problem of interrupted electric field therapy during power supply mode switching in current tumor electric field therapy devices. Through optimized design of the power supply switching circuit, multiple power supply devices can seamlessly switch power supply, ensuring that the power supply is not interrupted, thereby increasing the duration of the effective therapeutic electric field applied by the tumor electric field therapy device to the tumor tissue area and improving the treatment effect.

[0005] To achieve the above objectives, the main technical solutions adopted in this application include:

[0006] This application provides a tumor electric field therapy device, comprising: an electrode patch; an electric field generating device adapted to generate an alternating electrical signal, wherein the alternating electrical signal is applied to the electrode patch to apply an alternating electric field to a tumor site in the human body; a plurality of power supply devices, each of the plurality of power supply devices adapted to supply power to the electric field generating device; and a power supply switching circuit configured to connect a power supply path between one of the plurality of power supply devices and the electric field generating device based on the supply voltage of each power supply device, so that the plurality of power supply devices can seamlessly switch to supply power to the electric field generating device.

[0007] According to the tumor electric field therapy device provided in the embodiments of this application, through the optimized design of the power supply switching circuit, the power supply path between one of the multiple power supply devices and the electric field generator can be connected based on the power supply voltage of each power supply device. This allows multiple power supply devices to seamlessly switch to power the electric field generator, achieving seamless switching of power supply modes and ensuring that the power supply is not interrupted during the switching process. This improves the duration of the effective therapeutic electric field applied by the tumor electric field therapy device to the tumor tissue area and enhances the treatment effect.

[0008] Optionally, the power supply switching circuit includes: a plurality of unidirectional conducting devices, wherein the input terminal of each of the plurality of unidirectional conducting devices is connected to the power supply terminal of the corresponding power supply device, and the output terminals of the plurality of unidirectional conducting devices are connected together to serve as a power supply output terminal to provide power to the electric field generating device.

[0009] Optionally, the plurality of power supply devices include an adapter power supply device and a battery power supply device, and the plurality of unidirectional conducting devices include a first diode and a second diode, wherein the anode of the first diode is adapted to be connected to the power supply terminal of the adapter power supply device, the anode of the second diode is adapted to be connected to the power supply terminal of the battery power supply device, and the cathode of the second diode is connected to the cathode of the first diode to serve as the power supply output terminal.

[0010] Optionally, the power supply switching circuit further includes: a first capacitor, the first terminal of which is connected to the cathode of the second diode and the cathode of the first diode respectively, and the second terminal of the first capacitor is grounded.

[0011] Optionally, the nominal supply voltage of the adapter power supply device is greater than the maximum supply voltage of the battery power supply device.

[0012] Optionally, the power supply switching circuit further includes a controllable switching unit, which is disposed between the cathode of the second diode and the first terminal of the first capacitor, and is turned on or off based on the power supply voltage of the adapter power supply device and the power supply voltage of the battery power supply device, so as to enable seamless switching between the adapter power supply device and the battery power supply device.

[0013] Optionally, the controllable switching unit includes: a first MOSFET, a second MOSFET, and a third MOSFET. The gate of the first MOSFET is adapted to be connected to the anode of the first diode, the drain of the first MOSFET is adapted to be connected to the cathode of the second diode, the source of the first MOSFET is grounded, the gate of the second MOSFET is connected to the drain of the first MOSFET, the drain of the second MOSFET is adapted to be connected to the gate of the third MOSFET, the source of the second MOSFET is grounded, the source of the third MOSFET is connected to the cathode of the second diode, and the drain of the third MOSFET is adapted to be connected to the power supply output terminal.

[0014] Optionally, the first MOS transistor and the second MOS transistor are NMOS transistors, and the third MOS transistor is a PMOS transistor.

[0015] Optionally, the controllable switching unit further includes: a third diode, the anode of the third diode being connected to the anode of the first diode, and the cathode of the third diode being adapted to be connected to the gate of the first MOS transistor.

[0016] Optionally, the aforementioned tumor electric field therapy device further includes: a signal acquisition device configured to acquire the power supply voltage of each power supply device and the power supply output voltage of the power supply switching circuit; an indicator device; and a control device connected to the signal acquisition device and the indicator device, respectively, configured to determine the power supply mode of the tumor electric field therapy device based on the power supply voltage of each power supply device and the power supply output voltage, and to control the indicator device to issue power supply indication information. Attached Figure Description

[0017] To more clearly illustrate the technical solutions in the specific embodiments of this application or the prior art, the drawings used in the description of the specific embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of this application. For those skilled in the art, other drawings can be obtained from these drawings without creative effort.

[0018] Figure 1 This is a structural block diagram of a tumor electric field therapy device provided in one embodiment of this application;

[0019] Figure 2 A circuit diagram of the power supply switching device for the tumor electric field therapy device provided in the first embodiment of this application;

[0020] Figure 3 A circuit diagram of the power supply switching device for the tumor electric field therapy device provided in the second embodiment of this application;

[0021] Figure 4 A schematic diagram of an indicator light circuit provided in one embodiment of this application;

[0022] Figure 5 This is a schematic diagram of a buzzer alarm circuit provided in one embodiment of this application. Detailed Implementation

[0023] To make the objectives, technical solutions, and advantages of the embodiments of this application clearer, the technical solutions of the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this application, not all embodiments. Based on the embodiments of this application, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this application.

[0024] In related technologies, tumor electric field therapy devices for tumor treatment mainly include a tumor electric field therapy instrument and an electrode patch electrically connected to the tumor electric field therapy instrument. The tumor electric field therapy instrument is used to generate an alternating electric field signal of a specific frequency. This alternating electric field signal is applied to the tissue area where the tumor is located through the electrode patch applied to the skin of the corresponding lesion to perform electric field therapy, thereby inhibiting the proliferation or spread of tumor cells.

[0025] However, currently, tumor electric field therapy devices require the power to be turned off and the electric field therapy to be paused during the power supply mode switching process. After the power supply mode switching is completed, the power is turned back on to resume the electric field therapy. This causes the power supply to be interrupted during the switching between power supply modes, which in turn causes the electric field therapy to be interrupted, thereby shortening the duration of effective electric field therapy and reducing the treatment effect.

[0026] Therefore, the tumor electric field therapy device provided in this application, through the optimized design of the power supply switching circuit, enables multiple power supply devices to seamlessly switch power supply, ensuring that the power supply is not interrupted, thereby increasing the duration of the effective therapeutic electric field applied by the tumor electric field therapy device to the tumor tissue area and improving the treatment effect.

[0027] The tumor electric field therapy device with a power supply switching circuit provided in the embodiments of this application will now be described in detail with reference to the accompanying drawings.

[0028] refer to Figure 1The diagram shown is a structural block diagram of a tumor electric field therapy device 1000 according to an embodiment of this application. The tumor electric field therapy device 1000 includes a tumor electric field therapy instrument 100, a downstream load 160, and a power supply switching device 130. The tumor electric field therapy instrument 100 can be seamlessly powered by multiple power supply devices, such as a first power supply device 110 and a second power supply device 120. The power supply switching device 130 can be installed in the tumor electric field therapy instrument 100 and is configured to control the switching of multiple power supply devices, such as seamlessly switching between the first power supply device 110 and the second power supply device 120, to provide uninterrupted power to the downstream load 160. The downstream load 160 may include an electric field generating device (not shown) disposed within the tumor electric field therapy device 100 and a plurality of electrode patches (not shown) disposed outside the tumor electric field therapy device 100 and electrically connected to the electric field generating device (not shown). The electric field generating device (not shown) is powered by a first power supply device 110 or a second power supply device 120 to generate an alternating electrical signal. This alternating electrical signal is applied to the tumor tissue region through the electrode patches (not shown) to inhibit the proliferation or spread of tumor cells. Optionally, in some embodiments of this application, the downstream load 160 may further include an adapter (not shown). The alternating electrical signal generated by the electric field generating device (not shown) is output through the adapter (not shown) to generate multiple pairs of alternating electrical signals. These multiple pairs of alternating electrical signals are alternately applied to the tumor tissue region through multiple pairs of electrode patches (not shown) to inhibit the proliferation or spread of tumor cells.

[0029] refer to Figures 1 to 3 As shown in some embodiments of this application, the tumor electric field therapy device 1000 includes an electrode patch (not shown), an electric field generator (not shown), multiple power supply devices such as a first power supply device 110 and a second power supply device 120, and power supply switching circuits 1300 and 1300'. The electric field generator is adapted to generate an alternating electrical signal, which is applied to the electrode patch to apply an alternating electric field to a tumor site in the human body. Each of the multiple power supply devices is adapted to supply power to the electric field generator. The power supply switching circuits 1300 and 1300' are configured to connect the power supply path between one of the multiple power supply devices and the electric field generator based on the supply voltage of each power supply device, so that the multiple power supply devices can seamlessly switch to supply power to the electric field generator.

[0030] In other words, the power supply switching device 130 may include multiple power supply input terminals, such as... Figure 2 or Figure 3 The nodes ① and ② shown, and the power output terminals, are as follows: Figure 2 or Figure 3As shown in node ③ and power switching circuits 1300 and 1300', each of the multiple power input terminals is connected to the power supply terminal of the corresponding power supply device, and the power output terminal is connected to the downstream load 160. The power switching circuits 1300 and 1300' are configured to connect one of the multiple power input terminals to the power output terminal based on the power supply voltage of each power supply device, so that the multiple power supply devices can seamlessly switch to supply power to the downstream load 160.

[0031] Specifically, in one example of this application, the multiple power supply devices may include two. The following description uses two power supply devices as an example, namely, the multiple power supply devices include a first power supply device 110 and a second power supply device 120. It is understood that the power supply devices can be external power supply devices independent of the tumor electric field therapy device 100, or internal power supply devices disposed within the tumor electric field therapy device 100. For example, the first power supply device 110 is an external power supply device independent of the tumor electric field therapy device 100, such as an adapter power supply device, which connects to the mains power supply via an adapter to provide power. The second power supply device 120 is an internal power supply device disposed within the tumor electric field therapy device 100, such as a battery power supply device, wherein the battery can be a rechargeable battery.

[0032] In one embodiment of this application, reference is made to Figure 2 or Figure 3 As shown, the power supply switching circuits 1300 and 1300' include: multiple unidirectional conducting devices, the input terminal of each unidirectional conducting device is connected to the power supply terminal of the corresponding power supply device, and the output terminals of the multiple unidirectional conducting devices are connected together to serve as a power supply output terminal to provide power to the electric field generating device.

[0033] In the case where multiple power supply devices include a first power supply device 110 (e.g., an adapter power supply device) and a second power supply device 120 (e.g., a battery power supply device), multiple unidirectional conducting devices include a first diode D1 and a second diode D2. The power supply switching circuit 1300 may also include a first capacitor C1. The anode of the first diode D1 is adapted to be connected to the power supply terminal of the first power supply device 110 (e.g., an adapter power supply device), and the anode of the second diode D2 is adapted to be connected to the power supply terminal of the second power supply device 120 (e.g., a battery power supply device). After the cathode of the second diode D2 is connected to the cathode of the first diode D1, it serves as the power supply output terminal, that is, power can be output at node ③. The first terminal of the first capacitor C1 is connected to the cathode of the second diode D2 and the cathode of the first diode D1, respectively, and the second terminal of the first capacitor C1 is grounded.

[0034] In the embodiments of this application, by optimizing the power supply switching circuit 1300 and cleverly utilizing the unidirectional conduction characteristics of the diode, the first power supply device 110 and the second power supply device 120 can seamlessly switch to supply power to the load 160, such as the electric field generator, so that the power supply to the subsequent load 160 is not interrupted. In this way, electric field therapy can continue during the power supply switching process, thereby increasing the duration of the effective therapeutic electric field applied by the tumor electric field therapy device 100 to the tumor tissue area and improving the treatment effect.

[0035] The tumor electric field therapy device 1000 with a power supply switching circuit provided in this application will be described in detail below through two specific embodiments.

[0036] Example 1

[0037] like Figure 2 The diagram shown is a circuit diagram of a tumor electric field therapy device 1000 with a power supply switching circuit 1300 according to the first embodiment of this application. In this embodiment, the nominal power supply voltage output by the first power supply device 110, such as an adapter power supply device, is greater than the maximum power supply voltage output by the second power supply device 120, such as a battery power supply device. The power supply switching circuit 1300 includes a first diode D1, a second diode D2, and a first capacitor C1. The anode of the first diode D1 is electrically connected to the output terminal of the first power supply device 110, and the cathode of the first diode D1 is electrically connected to the input terminal of the subsequent load 160. The anode of the second diode D2 is electrically connected to the output terminal of the second power supply device 120, and the cathode of the second diode D2 is electrically connected to the input terminal of the subsequent load 160. The first terminal of the first capacitor C1 is electrically connected to the cathode of the first diode D1 and the cathode of the second diode D2, and the second terminal of the first capacitor C1 is grounded.

[0038] Optionally, the first diode D1 and the second diode D2 are Schottky diodes or ultrafast recovery diodes, and the first capacitor C1 is an electrolytic capacitor.

[0039] In this embodiment, the first capacitor C1 not only stabilizes the voltage and reduces voltage ripple when the power supply is turned on, but also temporarily supplies power to the downstream load 160 to prevent voltage drop during the switching between the first power supply device 110 and the second power supply device 120. This is because the first diode D1 and the second diode D2 each have a cutoff time and a conduction time when they are turned off and on. In other words, there is a short switching period during the power supply switching process. During this switching period, neither the first power supply device 110 nor the second power supply device 120 can supply power to the downstream load 160 because of the short conduction or cutoff time of the diodes. Therefore, the first capacitor C1 is needed to temporarily supply power to the downstream load 160 to ensure that the entire power supply is completely seamlessly switched.

[0040] Therefore, the power supply switching circuit 1300 of this application, based on the unidirectional conduction characteristics of diodes and the voltage regulation and energy storage characteristics of capacitors, can ensure that the power supply is not interrupted during the power supply switching process, realize seamless switching of power supply mode, thereby ensuring the continuous operation of electric field therapy and avoiding affecting the treatment effect.

[0041] To ensure rapid power supply switching, Schottky diodes or ultra-fast recovery diodes are typically selected because these diodes have short conduction and cutoff times, usually in the nanosecond range. Combined with the characteristics of electrolytic capacitors, seamless power switching between the first power supply device 110 and the second power supply device 120 can be achieved.

[0042] For example, the first power supply device 110 is an adapter power supply device, and the second power supply device 120 is a battery power supply device, with the adapter supply voltage being greater than the battery supply voltage. When the initial adapter is not connected and the tumor electric field therapy device 100 is powered by the battery, at this time, [the following text is incomplete and requires further context to translate accurately]. Figure 2 As shown, the voltage at node ② is the battery output voltage, and the voltage at node ① is 0V. With the second diode D2 conducting and the first diode D1 cut off, the voltage at node ③ is the battery output voltage. When the tumor electric field therapy device 100 is operating normally, inserting the adapter causes the voltage at node ① to change from 0V to the adapter output voltage, which is greater than the battery output voltage at node ②. The first diode D1 conducts, causing the voltage at node ③ to become the adapter output voltage, while the second diode D2, subjected to reverse voltage, becomes cut off, cutting off battery power. Thus, the adapter supplies power to the downstream load 160. This completes the switch from battery power to adapter power. During this switch, the power supply to the downstream load 160 is not interrupted, thus not affecting the electric field therapy effect. In adapter power mode, the battery can be removed or placed inside the tumor electric field therapy device 100. The adapter will not charge the battery placed inside the tumor electric field therapy device 100.

[0043] Furthermore, when the tumor electric field therapy device 100 is operating normally and it is necessary to switch from adapter power to battery power, it is necessary to first confirm whether the battery is inside the tumor electric field therapy device 100. If there is no battery inside, it must be correctly connected first. After confirming that the battery is correctly inside the tumor electric field therapy device 100, disconnect the adapter power supply. At this time, the voltage at node ② is the battery output voltage, the voltage at node ① is 0V, the second diode D2 is conducting, and the first diode D1 is cut off due to reverse voltage. Then, the voltage at node ③ is the battery output voltage, and the battery supplies power to the downstream load 160. This completes the switch from adapter power to battery power. During this switch, the power supply to the downstream load 160 will not be interrupted, thus not affecting the electric field therapy effect.

[0044] In some embodiments of this application, such as Figure 3As shown, the power supply switching circuit 1300 also includes a controllable switch unit 1301. The controllable switch unit 1301 is disposed between the cathode of the second diode D2 and the first terminal of the first capacitor C1, and is turned on or off based on the power supply voltage of the first power supply device 110, such as the adapter power supply device, and the power supply voltage of the second power supply device 120, such as the battery power supply device, so as to enable seamless switching between the adapter power supply device and the battery power supply device.

[0045] Specifically, when the second power supply device 120 is connected to the tumor electric field therapy device 1000 and the first power supply device 110 is not connected to the tumor electric field therapy device 1000, the controllable switch unit 1301 is turned on to supply power to the downstream load 160 through the second power supply device 120; when the second power supply device 120 is connected to the tumor electric field therapy device 1000 and the first power supply device 110 is connected to the tumor electric field therapy device 1000, the controllable switch unit 1301 is turned off to supply power to the downstream load 160 through the first power supply device 110; when both the first power supply device 110 and the second power supply device 120 are connected to the tumor electric field therapy device 1000, and then the first power supply device 110 is removed from the tumor electric field therapy device 1000, the controllable switch unit 1301 is turned on to supply power to the downstream load 160 through the second power supply device 120.

[0046] In this embodiment, by setting the controllable switch unit 1301 in a suitable position, seamless switching of power supply between the two can be achieved regardless of the magnitude relationship between the power supply voltage output by the second power supply device 120 and the power supply voltage output by the first power supply device 110.

[0047] Specifically, such as Figure 3 As shown, the controllable switching unit 1301 includes a first MOSFET Q1, a second MOSFET Q2, and a third MOSFET Q3. The gate of the first MOSFET Q1 is adapted to be connected to the anode of the first diode D1, the drain of the first MOSFET Q1 is adapted to be connected to the cathode of the second diode D2, and the source of the first MOSFET Q1 is grounded. The gate of the second MOSFET Q2 is connected to the drain of the first MOSFET Q1, the drain of the second MOSFET Q2 is adapted to be connected to the gate of the third MOSFET Q3, the source of the second MOSFET Q2 is grounded, the source of the third MOSFET Q3 is connected to the cathode of the second diode D2, and the drain of the third MOSFET Q3 is adapted to be connected to the power supply output terminal.

[0048] Among them, the first MOSFET Q1 and the second MOSFET Q2 are NMOS transistors, and the third MOSFET Q3 is a PMOS transistor.

[0049] Based on the cooperation of the first MOSFET Q1, the second MOSFET Q2 and the third MOSFET Q3, the controllable switching unit 1301 can be turned on or off, thereby realizing seamless switching between the second power supply device 120 and the first power supply device 110.

[0050] Specifically, the tumor electric field therapy device 1000 with a power supply switching circuit 1300' provided in this application will be described through a second embodiment.

[0051] Example 2

[0052] like Figure 3The diagram shown is a circuit diagram of a tumor electric field therapy device 1000 with a power supply switching circuit 1300' provided in the second embodiment of this application. In this embodiment, the power supply voltage output by the first power supply device 110 can be greater than, less than, or equal to the power supply voltage output by the second power supply device 120. Compared to the power supply switching circuit 1300 provided in Embodiment 1, the power supply switching circuit 1300' in this embodiment, in addition to including the first diode D1, the second diode D2, and the first capacitor C1, also includes a controllable switching unit 1301. The controllable switching unit 1301 includes a first MOSFET Q1, a second MOSFET Q2, and a third MOSFET Q3. The gate of the first MOSFET is electrically connected to the anode of the first diode D1, the drain of the first MOSFET is electrically connected to the cathode of the second diode D2, and the source of the first MOSFET is grounded. The gate of the second MOSFET is electrically connected to the drain of the first MOSFET, the drain of the second MOSFET is electrically connected to the gate of the third MOSFET, and the source of the second MOSFET is grounded. The source of the third MOSFET is electrically connected to the cathode of the second diode, and the drain of the third MOSFET is electrically connected to the input terminal of the subsequent load 160. The first MOSFET Q1 and the second MOSFET Q2 are NMOS transistors, and the third MOSFET Q3 is a PMOS transistor. A third diode D3 and a resistor R7 can be disposed between the gate of the first MOSFET Q1 and the anode of the first diode D1. The anode of the third diode D3 is connected to the anode of the first diode D1, and the cathode of the third diode D3 is connected to the gate of the first MOSFET Q1 through the resistor R7. The function of the third diode D3 is to prevent reverse current flow. The resistor R7 acts as a current-limiting resistor and, together with the resistor R8, forms a voltage divider circuit to limit the gate voltage input to the first MOSFET Q1. When the first power supply device 110 is connected, the current from the first power supply device 110 will flow into the gate of the first MOSFET Q1. The presence of the resistor R7 can limit the current flowing into the gate of the first MOSFET Q1, so that the gate is not subjected to too large an impact at the moment of current inflow, thus preventing damage to the MOSFET. The resistor R8 connected between the gate of the first MOSFET Q1 and GND forms a voltage divider with resistor R7, ensuring that the Vgs voltage of the first MOSFET Q1 is greater than or equal to its own Vgs(th) voltage after the first power supply device 110 is connected, allowing it to conduct smoothly. Simultaneously, it also ensures that the current from the first power supply device 110 does not directly flow into the gate of the first MOSFET Q1, preventing the first MOSFET Q1 from burning out due to an excessively high Vgs voltage. A resistor R10 can also be provided between the drain of the first MOSFET Q1 and the cathode of the second diode D2. One end of resistor R10 connected to the drain of the first MOSFET Q1 is connected to resistor R9, and the other end of resistor R9 connected to resistor R10 is connected to the gate of the second MOSFET Q2. The other end of resistor R9 is grounded.Resistor R9 and resistor R10 also form a voltage divider network. Their function is to ensure that when the first MOSFET Q1 is not turned on, the voltage divider formed by resistors R9 and R10 can make the Vgs voltage of the second MOSFET Q2 greater than or equal to the Vgs(th) voltage of the second MOSFET Q2 itself, thus ensuring that the second MOSFET Q2 can be turned on smoothly. At the same time, it also ensures that the current of the second power supply device 120 will not be directly poured into the gate of the second MOSFET Q2, which would cause the second MOSFET Q2 to burn out due to the excessively large Vgs voltage. A resistor R11 can be placed between the source and gate of the third MOSFET Q3, and a resistor R12 can be placed between the gate of the third MOSFET Q3 and the drain of the second MOSFET Q2. These resistors R11 and R12 also form a voltage divider network. Their function is to ensure that when the second MOSFET Q2 is turned on, the voltage divided by resistors R11 and R12 can make the Vgs voltage of the third MOSFET Q3 less than or equal to the Vgs(th) voltage of the third MOSFET Q3 itself, so as to ensure that the third MOSFET Q3 can be turned on smoothly.

[0053] For example, the first power supply device 110 is an adapter-powered device, and the second power supply device 120 is a battery-powered device. (See reference...) Figure 3 As shown, when the initial adapter is not connected and the tumor electric field therapy device 100 is powered by the battery, the voltage V1 at node ① is 0V, the first MOSFET Q1 is not conducting (equivalent to an open circuit), the voltage V2 at node ② is the battery output voltage, the second diode D2 is conducting, and the voltage V7 at node ⑦ is also the battery output voltage. The voltage V5 at node ⑤ is: V5 = V7 * R9 / (R9 + R10). Due to the voltage at node ⑤, the second MOSFET is grounded, resulting in a negative voltage between nodes ⑥ and ⑦, which turns on the third MOSFET Q3. Thus, the voltage V3 at node ③ is the battery output voltage, and the first diode D1 is cut off due to reverse voltage. Therefore, the battery supplies power to the downstream load 160.

[0054] In this embodiment, when the tumor electric field therapy device 100 is in normal working condition, the battery power supply is switched to the adapter power supply, which is described in three cases: Case A is that the adapter power supply voltage is greater than the battery power supply voltage, Case B is that the adapter power supply voltage is less than the battery power supply voltage, and Case C is that the adapter power supply voltage is equal to the battery power supply voltage.

[0055] Scenario A: The adapter supply voltage is greater than the battery supply voltage.

[0056] When the adapter is inserted, the voltage V1 at node ① becomes the adapter output voltage. This causes the first diode D1 to conduct, making the voltage V3 at node ③ the adapter output voltage. Simultaneously, it turns the first MOSFET Q1 to ground, causing the voltage V5 at node ⑤ to become 0V. This results in the second MOSFET Q2 being cut off, eliminating the voltage difference between nodes ⑥ and ⑦, and consequently, the third MOSFET Q3 being cut off. The adapter output voltage is then transmitted through the body diode of the third MOSFET Q3, causing the voltage V7 at node ⑦ to become the adapter output voltage. Meanwhile, the voltage V2 at node ② remains the battery output voltage. Since V2 < V7, the second diode D2 is reverse-biased and cuts off battery power, allowing the adapter to supply power to the downstream load 160. This completes the switch from battery power to adapter power. During this switch, the power supply to the downstream load 160 is not interrupted, thus maintaining the electric field therapy effect.

[0057] Scenario B: The adapter supply voltage is lower than the battery supply voltage.

[0058] When the adapter is inserted, the voltage V1 at node ① becomes the adapter output voltage. This causes the first diode D1 to conduct, and the voltage V3 at node ③ to become the adapter output voltage. Simultaneously, it turns the first MOSFET Q1 to ground, and the voltage V5 at node ⑤ becomes 0V, causing the second MOSFET Q2 to turn off, eliminating the voltage difference between nodes ⑥ and ⑦, thus turning off the third MOSFET Q3. Meanwhile, the voltage V2 at node ② remains the battery output voltage. Since V2 > V3, the second diode D2 remains conducting, and the voltage V7 at node ⑦ remains the battery output voltage. Because the third MOSFET Q3 is off and V7 > V3, the body diode of the third MOSFET Q3 is subjected to reverse voltage and cut off, thus cutting off battery power at the third MOSFET Q3 and preventing further power supply to the downstream load 160. The adapter then supplies power to the downstream load 160. This completes the switch from battery power to adapter power. During this switch, the power supply to the downstream load 160 is not interrupted, thus not affecting the electric field therapy effect.

[0059] Case C: Adapter supply voltage equals battery supply voltage

[0060] When the adapter is inserted, the voltage V1 at node ① becomes the adapter output voltage. This causes the first diode D1 to conduct, the voltage V3 at node ③ to become the adapter output voltage, and the first MOSFET Q1 to conduct and ground, causing the voltage V5 at node ⑤ to become 0V. This results in the second MOSFET Q2 being cut off, eliminating the voltage difference between nodes ⑥ and ⑦, and consequently, the third MOSFET Q3 being cut off. Meanwhile, the voltage V2 at node ② remains the battery output voltage. At this point, V2 = V3, and there is no voltage difference between nodes ② and ③. Therefore, both the second diode D2 and the body diode of the third MOSFET Q3 are not conducting, cutting off battery power. Power is no longer supplied to the downstream load 160 at the second diode D2, and the adapter supplies power to the downstream load 160. This completes the switch from battery power to adapter power. During this switch, the power supply to the downstream load 160 is not interrupted, thus not affecting the electric field therapy effect.

[0061] When the tumor electric field therapy device 100 is in normal working condition, and it is necessary to switch from adapter power supply to battery power supply, it is necessary to first confirm whether the battery is inside the tumor electric field therapy device 100. If there is no battery inside, it needs to be correctly connected first. After confirming that the battery is correctly inside the tumor electric field therapy device 100, disconnect the adapter power supply. At this time, even if the adapter power supply voltage is greater than, less than or equal to the battery power supply voltage, the voltage V1 at node ① becomes 0V, making the first MOSFET Q1 non-conducting (equivalent to an open circuit), while the voltage V2 at node ② is the battery output voltage, making the second diode D2 conduct. Therefore, the voltage V7 at node ⑦ is also the battery output voltage, and the voltage V5 at node ⑤ is: V5 = V7 * R9 / (R9 + R10). Since there is voltage at node ⑤, the second MOSFET Q2 conducts and grounds, resulting in a negative voltage between nodes ⑥ and ⑦, which makes the third MOSFET Q3 conduct, making the voltage V3 at node ③ the battery output voltage, and the first diode D1 is cut off due to reverse voltage, thus the battery supplies power to the downstream load 160. This completes the switch from adapter power supply to battery power supply. During this switch, the power supply to the downstream load 160 will not be interrupted, thus affecting the electric field therapy effect.

[0062] Therefore, the power supply switching circuit 1300' designed in this embodiment can achieve seamless switching between battery power supply and adapter power supply regardless of the relationship between the adapter power supply voltage and the battery power supply voltage. That is, during the switching process, the power supply to the downstream load 160, such as the electric field generator, will not be interrupted, thus affecting the electric field therapy effect.

[0063] Optionally, in some embodiments of this application, such as Figure 2 or Figure 3As shown, the tumor electric field therapy device 100 also includes multiple resistor voltage divider networks for voltage detection to determine whether there is a power supply abnormality and to determine the power supply mode. Resistors R1 and R2 form a first voltage divider network for the first power supply device 110. The first end of resistor R1 is electrically connected to the power supply terminal of the first power supply device 110 and the anode of the first diode D1. The second end of resistor R1 is electrically connected to the first end of resistor R2. The second end of resistor R2 is electrically connected to the negative output terminal and ground (GND) of the first power supply device 110. The node between resistors R1 and R2 is electrically connected to the signal acquisition device 140. Resistors R5 and R6 form a second voltage divider network for the second power supply device 120. The first end of resistor R5 is electrically connected to the power supply terminal of the second power supply device 120 and the anode of the second diode D2. The second end of resistor R5 is electrically connected to the first end of resistor R6. The second end of resistor R6 is electrically connected to the negative output terminal and ground (GND) of the second power supply device 120. The node between resistors R5 and R6 is electrically connected to the signal acquisition device 140. Resistors R3 and R4 form a third voltage divider network for the power supply output. The first terminal of resistor R3 is electrically connected to the positive input terminal of the subsequent load 160 and the cathode of the first diode D1. The second terminal of resistor R3 is electrically connected to the first terminal of resistor R4, and the second terminal of resistor R4 is electrically connected to the negative input terminal of the subsequent load 160 and the ground terminal (GND). The node between resistors R3 and R4 is electrically connected to the signal acquisition device 140. Therefore, the signal acquisition device 140 is configured to acquire the supply voltage and power supply output voltage of each power supply device.

[0064] Taking the first voltage divider network formed by resistors R1 and R2 for the first power supply device 110 as an example, the actual value of the power supply voltage is calculated. (Ref) Figure 2 As shown, the signal acquisition device 140 is electrically connected to the first voltage divider network and the control device 150, respectively. It is configured to acquire the voltage signal at node ④ and transmit the voltage signal to the control device 150. The control device 150 calculates the voltage value V4 at node ④ based on the received voltage signal. Then, based on the voltage value V4 at node ④, the voltage value V1 at node ① can be calculated: V1 = V4 * (R1 + R2) / R2. The voltage value V1 at node ① is the actual value of the power supply voltage output by the first power supply device 110. Using a similar method, the actual value V2 of the power supply voltage output by the second power supply device 120 at node ② and the actual value V3 of the power supply voltage received at node ③ can be calculated.

[0065] The control device 150 is further configured to determine the power supply mode of the tumor electric field therapy device 1000 and whether there is a power supply abnormality based on the voltage value V1 at node ①, the voltage value V2 at node ② and the voltage value V3 at node ③, so as to provide clear power supply indication information.

[0066] As can be seen, the tumor electric field therapy device 1000 of this application embodiment includes a plurality of power supply devices, a downstream load 160, and a power supply switching circuit described in the above embodiment. Each of the plurality of power supply devices is adapted to supply power to the downstream load 160 respectively to apply an alternating electrical signal to the tumor site in the human body. The power supply switching circuit is configured to control the plurality of power supply devices to seamlessly switch to supply power to the downstream load 160 based on the power supply voltage of each power supply device.

[0067] Furthermore, the tumor electric field therapy device 1000 also includes a signal acquisition device 140, an indicator device 170, and a control device 150. The signal acquisition device 140 is configured to acquire the power supply voltage of each power supply device and the power supply output voltage of the power supply switching circuit. The control device 150 is connected to the signal acquisition device 140 and the indicator device 170 respectively. The control device 150 is configured to determine the power supply mode of the tumor electric field therapy device 1000 based on the power supply voltage and the power supply output voltage of each power supply device, and control the indicator device 170 to issue power supply indication information.

[0068] The indicator device 170 may include an indicator light circuit and a buzzer alarm circuit.

[0069] For example, refer to Figure 4 The diagram shown is a schematic of an indicator light circuit according to an embodiment of this application. The indicator light circuit includes a green LED for indicating the power supply status of the adapter (i.e., the first power supply device 110), a green LED and a yellow LED for indicating the power supply status of the battery (i.e., the second power supply device 120), and a red LED for indicating an abnormal power supply status. All LEDs are connected in parallel and are electrically connected to a corresponding I / O terminal of the control device 150. A current-limiting resistor may also be provided between each LED and the corresponding I / O terminal of the control device 150. For ease of description, the adapter indicator light is defined as green, the battery indicator light as a yellow-green dual-color light, and the abnormal indicator light as red.

[0070] refer to Figure 5 The diagram shown is a schematic of a buzzer alarm circuit according to an embodiment of this application. For ease of description, the buzzer alarm circuit includes a buzzer, a freewheeling diode and a MOSFET connected in parallel across the buzzer, the drain of the MOSFET being electrically connected to one end of the buzzer, the source of the MOSFET being grounded, and the gate of the MOSFET being electrically connected to the I / O terminal of the control device 150. The control device 150 is configured to control the indicator light circuit and the buzzer alarm circuit to issue clear power supply indication information.

[0071] Optionally, in one embodiment of this application, when multiple power supply devices include a first power supply device 110 and a second power supply device 120, and the first power supply device 110 is an adapter power supply device and the second power supply device 120 is a battery power supply device, the control device 150 stores a first preset voltage, a second preset voltage, a third preset voltage, a fourth preset voltage, and a fifth preset voltage set in descending order of voltage value. The control device 150 is further configured to, when the power supply voltage of the adapter power supply device is the first preset voltage (e.g., 40V), the power supply voltage of the battery power supply device is greater than or equal to zero and less than or equal to the second preset voltage (e.g., 33.6V), and the voltage at the power supply output terminal is equal to the power supply voltage of the adapter power supply device, the control indicator device 170 issues a power supply indication message indicating that the adapter power supply is functioning normally and there are no abnormalities, wherein the first preset voltage is greater than the second preset voltage; when the power supply voltage of the adapter power supply device is zero, the power supply voltage of the battery power supply device is greater than or equal to the third preset voltage (e.g., 25.6V) and less than or equal to the second preset voltage, ..., the control indicator device 170 issues a power supply indication message indicating that the adapter power supply is functioning normally and there are no abnormalities, wherein the first preset voltage is greater than the second preset voltage; and when the power supply voltage of the adapter power When the supply voltage of the battery-powered device is constant, the control indicator 170 issues a power supply indication message indicating that the battery is powered and there are no abnormalities. When the supply voltage of the adapter-powered device is zero, the supply voltage of the battery-powered device is greater than or equal to the fourth preset voltage (e.g., 24.0V) and less than the third preset voltage, and the voltage at the power supply output terminal is equal to the supply voltage of the battery-powered device, the control indicator 170 issues a power supply indication message indicating that the battery is powered and the battery power is low. When the supply voltage of the adapter-powered device is zero, the supply voltage of the battery-powered device is greater than or equal to the fifth preset voltage (e.g., 22.4V) and less than the fourth preset voltage, and the voltage at the power supply output terminal is equal to the supply voltage of the battery-powered device, the control indicator 170 issues a power supply indication message indicating that the battery is powered and the battery power is almost depleted. When the supply voltage of the adapter-powered device is zero, the supply voltage of the battery-powered device is less than the fifth preset voltage, and the voltage at the power supply output terminal is equal to the supply voltage of the battery-powered device, the control indicator 170 issues a power supply indication message indicating that the battery voltage is insufficient to maintain power supply.

[0072] In the first embodiment described above, when the nominal supply voltage of the adapter power supply device is greater than the maximum supply voltage of the battery power supply device, and the power supply switching circuit 1300 does not include a controllable switch unit 1301, the control device 150 is further configured to, when the supply voltage of the adapter power supply device is greater than or equal to a fifth preset voltage and less than a first preset voltage, the supply voltage of the battery power supply device is greater than or equal to zero and less than or equal to a second preset voltage, the supply voltage of the adapter power supply device is greater than or equal to the supply voltage of the battery power supply device, and the voltage at the power supply output terminal is equal to the supply voltage of the adapter power supply device, the control indicator device 170 issues a power supply indication message indicating that the adapter power supply is abnormal and the adapter voltage is abnormal; when the supply voltage of the adapter power supply device is greater than or equal to a fifth preset voltage and less than a first preset voltage, the supply voltage of the battery power supply device is greater than or equal to zero and less than or equal to a second preset voltage, ... When the voltage of the adapter power supply is equal to the second preset voltage, the power supply voltage of the adapter power supply device is less than the power supply voltage of the battery power supply device, and the voltage at the power supply output terminal is equal to the power supply voltage of the battery power supply device, the control indicator device 170 issues a power supply indication message indicating that the battery power supply and adapter voltage are abnormal. When the power supply voltage of the adapter power supply device is greater than zero and less than the fifth preset voltage, the power supply voltage of the battery power supply device is greater than or equal to the fifth preset voltage and less than the second preset voltage, and the voltage at the power supply output terminal is equal to the power supply voltage of the battery power supply device, the control indicator device 170 issues a power supply indication message indicating that the battery power supply and adapter voltage are abnormal. When the power supply voltage of the adapter power supply device is greater than zero and less than the fifth preset voltage, and the power supply voltage of the battery power supply device is less than the fifth preset voltage, the control indicator device 170 issues a power supply indication message indicating that neither the adapter voltage nor the battery voltage is sufficient to maintain power supply.

[0073] Furthermore, regarding the second embodiment described above, when the power supply switching circuit 1300' includes a controllable switch unit 1301, the control device 150 is further configured to, when the power supply voltage of the adapter power supply device is greater than or equal to a fifth preset voltage and less than a first preset voltage, the power supply voltage of the battery power supply device is greater than or equal to zero and less than or equal to a second preset voltage, and the voltage at the power supply output terminal is equal to the power supply voltage of the adapter power supply device, issue a power supply indication message indicating that the adapter power supply is abnormal and the adapter voltage is abnormal; when the power supply voltage of the adapter power supply device is greater than zero and less than a fifth preset voltage, the power supply voltage of the battery power supply device is greater than or equal to zero and less than or equal to a second preset voltage, and the voltage at the power supply output terminal is equal to the power supply voltage of the adapter power supply device, issue a power supply indication message indicating that neither the adapter voltage nor the battery voltage is sufficient to maintain power supply.

[0074] In summary, the control device 150 is configured to determine the power supply mode of the tumor electric field therapy device 1000, such as whether it is powered by an adapter or a battery, based on the voltage value V1 at node ①, the voltage value V2 at node ②, and the voltage value V3 at node ③, and to determine whether there is a power supply abnormality in the tumor electric field therapy device 1000, as well as to control the indicator light circuit and the buzzer alarm circuit to provide clear power supply indication information.

[0075] In summary, the tumor electric field therapy device 1000 with a power supply switching circuit provided in this application embodiment can achieve seamless switching between two power supply modes, that is, the power supply will not be interrupted during the switching process between adapter power supply and battery power supply, thereby avoiding affecting the electric field therapy effect. At the same time, the control device 150 determines the power supply mode and whether there is a power supply abnormality based on the actual voltage values ​​of each node in the power supply switching circuit 1300 and 1300', and controls the indicator lights and buzzers to display clear power supply indication information, greatly improving the user experience.

[0076] In the description of this specification, the terms "one embodiment," "some embodiments," "embodiment," "example," "specific example," or "some examples," etc., refer to specific features, structures, materials, or characteristics described in connection with that embodiment or example, which are included in at least one embodiment or example of the present invention. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples. Moreover, without contradiction, those skilled in the art can combine and integrate the different embodiments or examples described in this specification, as well as the features of different embodiments or examples.

[0077] Although embodiments of the present invention have been shown and described above, it is understood that the above embodiments are exemplary and should not be construed as limiting the present invention. Those skilled in the art can make modifications, alterations, substitutions and variations to the above embodiments within the scope of the present invention.

Claims

1. A tumor electric field therapy device, characterized in that, include: Electrode patches; An electric field generating device, the electric field generating device being adapted to generate an alternating electric signal, wherein the alternating electric signal is applied to the electrode patch to apply an alternating electric field to a tumor site in the human body; Multiple power supply devices, each of which is adapted to supply power to the electric field generating device respectively; A power supply switching circuit is configured to connect the power supply path between one of the plurality of power supply devices and the electric field generator based on the power supply voltage of each power supply device, so that the plurality of power supply devices can seamlessly switch to supply power to the electric field generator.

2. The tumor electric field therapy device according to claim 1, characterized in that, The power supply switching circuit includes: Multiple unidirectional conducting devices are provided, with the input terminal of each unidirectional conducting device connected to the power supply terminal of the corresponding power supply device. The output terminals of the multiple unidirectional conducting devices are connected together to serve as a power supply output terminal to provide power to the electric field generating device.

3. The tumor electric field therapy device according to claim 2, characterized in that, The plurality of power supply devices include adapter power supply devices and battery power supply devices, and the plurality of unidirectional conducting devices include a first diode and a second diode, wherein... The anode of the first diode is adapted to be connected to the power supply terminal of the adapter power supply device, the anode of the second diode is adapted to be connected to the power supply terminal of the battery power supply device, and the cathode of the second diode is connected to the cathode of the first diode to serve as the power supply output terminal.

4. The tumor electric field therapy device according to claim 3, characterized in that, The power supply switching circuit also includes: The first capacitor has its first terminal connected to the cathode of the second diode and the cathode of the first diode, respectively, and its second terminal grounded.

5. The tumor electric field therapy device according to claim 3, characterized in that, The nominal supply voltage of the adapter power supply device is greater than the maximum supply voltage of the battery power supply device.

6. The tumor electric field therapy device according to claim 4, characterized in that, The power supply switching circuit also includes: A controllable switching unit is disposed between the cathode of the second diode and the first terminal of the first capacitor, and is turned on or off based on the power supply voltage of the adapter power supply device and the power supply voltage of the battery power supply device, so as to enable seamless switching between the adapter power supply device and the battery power supply device.

7. The tumor electric field therapy device according to claim 6, characterized in that, The controllable switching unit includes a first MOSFET, a second MOSFET, and a third MOSFET. The gate of the first MOSFET is adapted to be connected to the anode of the first diode, the drain of the first MOSFET is adapted to be connected to the cathode of the second diode, the source of the first MOSFET is grounded, the gate of the second MOSFET is connected to the drain of the first MOSFET, the drain of the second MOSFET is adapted to be connected to the gate of the third MOSFET, the source of the second MOSFET is grounded, the source of the third MOSFET is connected to the cathode of the second diode, and the drain of the third MOSFET is adapted to be connected to the power supply output terminal.

8. The tumor electric field therapy device according to claim 7, characterized in that, The first MOS transistor and the second MOS transistor are NMOS transistors, and the third MOS transistor is a PMOS transistor.

9. The tumor electric field therapy device according to claim 7, characterized in that, The controllable switching unit further includes a third diode, the anode of which is connected to the anode of the first diode, and the cathode of which is adapted to be connected to the gate of the first MOS transistor.

10. The tumor electric field therapy device according to any one of claims 1-9, characterized in that, Also includes: A signal acquisition device is configured to acquire the power supply voltage of each power supply device and the power supply output voltage of the power supply switching circuit; Indicating device; A control device is connected to the signal acquisition device and the indicator device respectively. The control device is configured to determine the power supply mode of the tumor electric field therapy device based on the power supply voltage of each power supply device and the power supply output voltage, and to control the indicator device to issue power supply indication information.

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