Probiotic tablet with multi-layered protective slow release structure
By designing a probiotic tablet with a multi-layered protective sustained-release structure, the problems of low survival rate of probiotic tablets in the gastric acid environment and difficulty in dosage were solved, thereby increasing the number of probiotics reaching the intestines and making it convenient to use in dosage.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- ZHENJIANG YUANSEN MEDICAL TECH CO LTD
- Filing Date
- 2025-06-16
- Publication Date
- 2026-06-26
AI Technical Summary
Current probiotic tablets have significantly reduced activity after passing through the acidic and bile salt environment of the stomach, resulting in insufficient quantities reaching the intestines and making them inconvenient for dosage.
A probiotic tablet with a multi-layered protective sustained-release structure was designed, comprising a centrally symmetrical enteric layer, an embedding layer one, and an embedding layer two. Different vitamin materials are used, and the tablet is dispensed in portions through an inner opening, an outer groove, and a channel, thereby enhancing the protection of probiotics in the acidic environment of the stomach and their survival in the intestines.
It improves the survival rate of probiotics in the acidic environment of the stomach, ensures the number of probiotics reaching the intestines, and facilitates convenient dosage through a multi-layer structure, enhancing the ease of use and accuracy of probiotic tablets.
Smart Images

Figure CN224404024U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of probiotic tablet technology, specifically to probiotic tablets with a multi-layered protective sustained-release structure. Background Technology
[0002] Probiotic tablets are a type of supplement containing probiotics. These probiotics are active microorganisms that colonize the human body and alter the composition of the gut microbiota in a specific part of the host. They are tablets made from these beneficial active microorganisms.
[0003] Currently, after taking probiotic tablets, the number of active probiotics that can maintain their activity and colonize the large intestine after passing through adverse environments such as stomach acid, choline, and bile salts is greatly reduced, failing to achieve the expected effect. Furthermore, probiotic tablets are usually made of a single compressed unit, and breaking them directly will cause the probiotics to be exposed, further reducing the number of probiotics entering the intestines. It is also inconvenient to use probiotic tablets in portions. Therefore, we have proposed probiotic tablets with a multi-layered protective sustained-release structure to solve the problems mentioned above. Utility Model Content
[0004] The purpose of this invention is to provide a probiotic tablet with a multi-layered protective sustained-release structure to solve the problem mentioned in the background art that the current probiotic tablets reach a small number of bacteria in the intestines, making it inconvenient to use probiotic tablets in measured doses.
[0005] To achieve the above objectives, this utility model provides the following technical solution: a probiotic tablet with a multi-layered protective sustained-release structure, comprising a tablet body, wherein four enteric layers are symmetrically arranged on the tablet body, an embedding layer I is provided within the enteric layer, an embedding layer II is provided within the embedding layer I, a probiotic core is provided within the embedding layer II, and an isolation layer is provided between the probiotic core and the embedding layer II, between the embedding layer II and the embedding layer I, and between the embedding layer I and the enteric layer, wherein an inner opening is provided at the center of the tablet body, an outer groove is provided at the outer edge of the tablet body, and a through groove is provided between the outer groove and the inner opening.
[0006] Preferably, the tablet body and the enteric coating are integrally extruded and formed using the same enteric coating material, and the enteric coating has a spherical structure on the tablet body.
[0007] Preferably, the first embedding layer and the second embedding layer are composed of different vitamins.
[0008] Preferably, the insulating layer is ethyl cellulose.
[0009] Preferably, both the outer groove and the through groove are located between the enteric coating layers.
[0010] Preferably, the through grooves are symmetrically arranged on the upper and lower sides of the tablet body.
[0011] Compared with the prior art, the beneficial effects of this utility model are:
[0012] (1) The probiotic tablet with a multi-layer protective sustained-release structure has an enteric coating layer, an embedding layer one and an embedding layer two on the outside of the probiotic core. The enteric coating layer can ensure that the probiotic tablet can safely pass through gastric acid, greatly reducing the killing effect of gastric acid on probiotics. At the same time, the embedding layer one and the embedding layer two are composed of different vitamins, which can increase the additional efficacy of the probiotic tablet while slowing down the release of probiotics to ensure the survival of probiotics in the intestine.
[0013] (2) The probiotic tablet with a multi-layered protective sustained-release structure has multiple probiotic cores on the tablet body, and each probiotic core is isolated by a separate enteric layer, an embedding layer one, and an embedding layer two, which enables the probiotic tablet to be broken open, thus facilitating the dispensing of the probiotic tablet. At the same time, the tablet body is provided with an inner opening, an outer groove, and a through groove, which makes it easier to separate and break the probiotic cores, avoiding the exposure of the probiotic cores due to breaking them in the wrong position, and improving the convenience and accuracy of the probiotic tablets in separate operation. Attached Figure Description
[0014] Figure 1 This is a three-dimensional structural diagram of the present invention;
[0015] Figure 2 This is a cross-sectional structural diagram of the present invention;
[0016] Figure 3 This is a cross-sectional structural diagram of the present invention.
[0017] In the diagram: 1. Tablet body; 2. Enteric coating layer; 3. Inner opening; 4. Outer groove; 5. Through groove; 6. Encapsulation layer one; 7. Encapsulation layer two; 8. Probiotic core; 9. Isolation layer. Detailed Implementation
[0018] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.
[0019] Please see Figure 1-3This utility model provides a technical solution: a probiotic tablet with a multi-layered protective sustained-release structure, including a tablet body 1, four enteric layers 2 symmetrically arranged on the tablet body 1, the tablet body 1 and the enteric layers 2 are integrally extruded and formed, using the same enteric material, and the enteric layers 2 have a spherical structure on the tablet body 1, which enables the probiotic core 8 to form individual structures on the tablet body 1 through the first embedding layer 6, the second embedding layer 7 and the enteric layers 2, which facilitates the dosage and use of the probiotic tablet.
[0020] The enteric layer 2 contains an embedding layer 6, the first embedding layer 6 contains an embedding layer 7, and the second embedding layer 7 contains a probiotic core 8.
[0021] Furthermore, the first encapsulation layer 6 and the second encapsulation layer 7 are composed of different vitamins, which can not only increase the sustained-release effect of the probiotic tablet, but also further enhance the efficacy of the probiotic tablet.
[0022] An isolation layer 9 is provided between the probiotic core 8 and the second embedding layer 7, between the second embedding layer 7 and the first embedding layer 6, and between the first embedding layer 6 and the enteric layer 2.
[0023] Furthermore, the isolation layer 9 is made of ethyl cellulose to prevent interlayer drug migration or chemical interactions, ensuring the normal structure of the probiotic tablet.
[0024] The tablet body 1 has an inner opening 3 in the center and an outer groove 4 on the outer side of the tablet body 1. A groove 5 is provided between the outer groove 4 and the inner opening 3.
[0025] Furthermore, both the outer groove 4 and the through groove 5 are located between the enteric layers 2. The through groove 5 is symmetrically arranged on the upper and lower sides of the tablet body 1. Through the inner through groove 3, the outer groove 4, and the through groove 5, the strength between the enteric layers 2 on the tablet body 1 can be effectively reduced, making the tablet body 1 easier to break open. At the same time, through the setting of the upper and lower through grooves 5, the corresponding strength is reduced, which can effectively prevent damage to the enteric layers 2 and ensure that the individual probiotic cores 8 are in normal condition, so as to facilitate the dosage and use of the probiotic tablet.
[0026] Specifically, when using this probiotic tablet with a multi-layered protective sustained-release structure, the probiotic tablet can be broken open according to the required dosage. There are multiple probiotic cores 8 on the tablet body 1. The tablet body 1 is generally sheet-shaped. The enteric layer 2, the first embedding layer 6, and the second embedding layer 7 wrap around the outside of the probiotic cores 8, forming a spherical structure with high strength. There are through grooves 5 in the gaps between them, and the two ends of the through grooves 5 are connected to the inner through opening 3 and the outer groove opening 4. All of these are to reduce the strength of the through grooves 5. Therefore, when the probiotic tablet is broken open, the through grooves 5 are easily broken by force, thereby realizing the separation of individual probiotic cores 8, which makes it convenient to take the probiotic tablet according to the required dosage.
[0027] When the probiotic tablet is taken, it can safely pass through the stomach acid and enter the intestine under the action of the tablet body 1 and the enteric layer 2. The tablet body 1 and the enteric layer 2 decompose rapidly. Under the action of the first encapsulation layer 6 and the second encapsulation layer 7, the probiotic core 8 continues to be safely transferred. Finally, after the first encapsulation layer 6 and the second encapsulation layer 7 are completely decomposed, the probiotic core 8 is safely located in the intestine.
[0028] The above completes the usage process of the probiotic tablets. Any content not described in detail in this instruction manual is existing technology known to those skilled in the art.
[0029] Although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present invention should be included within the protection scope of the present invention.
Claims
1. A probiotic tablet with a multi-layered protective sustained release structure comprising a tablet body (1) characterized in that: The tablet body (1) is symmetrically provided with four enteric coating layers (2), each enteric coating layer (2) is provided with an embedding layer one (6), each embedding layer one (6) is provided with an embedding layer two (7), and each embedding layer two (7) is provided with a probiotic core (8). An isolation layer (9) is provided between the probiotic core (8) and the second embedding layer (7), between the second embedding layer (7) and the first embedding layer (6), and between the first embedding layer (6) and the enteric layer (2); The tablet body (1) has an inner opening (3) at its center, and an outer groove (4) is provided on the outer side of the tablet body (1). A through groove (5) is provided between the outer groove (4) and the inner opening (3).
2. The probiotic tablet with multi-layered protective sustained release structure according to claim 1, characterized in that: The tablet body (1) and the enteric coating layer (2) are integrally extruded and formed using the same enteric coating material, and the enteric coating layer (2) has a spherical structure on the tablet body (1).
3. The probiotic tablet with a multi-layered protective sustained-release structure according to claim 1, characterized in that: The first (6) and the second (7) of the embedding layer are composed of different vitamins.
4. The probiotic tablet with a multi-layered protective sustained-release structure according to claim 1, characterized in that: The isolation layer (9) is ethyl cellulose.
5. The probiotic tablet with a multi-layered protective sustained-release structure according to claim 1, characterized in that: The outer groove (4) and the through groove (5) are both located between the enteric coating layer (2).
6. The probiotic tablet with a multi-layered protective sustained-release structure according to claim 1, characterized in that: The through groove (5) is symmetrically arranged on the upper and lower sides of the tablet body (1).