Platelet-rich plasma preparation device

Abstract

The utility model provides a kind of platelet-rich plasma preparation device, including upper cover, pipe body and lower cover, be provided with injection inlet on upper cover, be provided with through-hole on lower cover, lower cover can be close to or away from the movement of pipe body along the axis of pipe body, be provided with upper isolator and lower isolator in pipe body, upper isolator separates the upper cavity and lower cavity in pipe body, be provided with liquid outlet on upper isolator, lower isolator is set on lower cover and can move with lower cover, lower isolator separates the liquid chamber and extraction channel in lower cavity, be provided with extraction port on lower isolator, through-hole, extraction port and liquid outlet correspond, be provided with the shielding member of shielding extraction port in extraction port, lower isolator and shielding member can be blocked or release liquid outlet with the movement of lower cover;Only centrifugation is needed in preparation process, red blood cell and platelet-rich plasma can be completely separated by the movement of lower cover away from pipe body, structure is simple, convenient to operate, improve the efficiency and purity of separation extraction.

Description

Technical Field

[0001] This utility model relates to the field of platelet extraction technology, specifically to a platelet-rich plasma preparation device. Background Technology

[0002] Platelet-rich plasma (PRP) is a platelet concentrate obtained by centrifuging autologous whole blood. The PRP preparation device is a key piece of equipment for separating high concentrations of platelets, directly affecting the purity, activity, and clinical safety of PRP.

[0003] Traditional platelet preparation devices often employ an open system design, requiring manual intervention in multiple steps, including anticoagulant preloading, blood transfer, and centrifugation parameter adjustment. For example, one type of device requires pre-adding anticoagulant to the blood collection syringe, transferring the blood to a centrifuge tube after collection, and manually aspirating the PRP layer after centrifugation. This process involves multiple penetrations of the sterile barrier, increasing the risk of microbial contamination and demanding high operator skills, thus exacerbating operational complexity. Furthermore, a two-step centrifugation process is commonly used: low-speed centrifugation separates plasma and red blood cells, but platelets remain suspended in the plasma; high-speed centrifugation concentrates platelets to the plasma supernatant. This process is time-consuming and requires manual intervention to switch centrifugation conditions. Excessive preparation time not only limits its application in emergency settings but may also lead to decreased platelet activity due to prolonged exposure to the in vitro environment. Moreover, traditional preparation devices lack physical isolation mechanisms, resulting in a blurred interface between red blood cells and the PRP layer after centrifugation, making it easy to accidentally aspirate red blood cells during manual extraction. If red blood cells are not completely separated, the hemoglobin released after red blood cell lysis may activate inflammatory pathways, leading to adverse reactions such as pain and swelling at the injection site. Therefore, given the limitations of existing platelet-rich plasma (PRP) preparation devices, there is a need to design a convenient device that can completely separate red blood cells from PRP. Summary of the Invention

[0004] The purpose of this invention is to provide a platelet-rich plasma preparation device to solve the above-mentioned problems.

[0005] The technical solution adopted in this utility model is as follows:

[0006] A platelet-rich plasma (PRP) preparation device includes an upper cover, a tube body, and a lower cover arranged in sequence. An injection port is provided on the upper cover, and a through hole is provided on the lower cover. The lower cover can move closer to or away from the tube body along its axis. An upper and lower isolator are provided within the tube body. The upper isolator divides the interior of the tube body into an upper cavity and a lower cavity, and has a liquid outlet. The lower isolator is located on the lower cover and can move with it, dividing the lower cavity into a dispensing chamber and an extraction channel. An extraction port is provided on the lower isolator. The through hole, extraction port, and liquid outlet correspond to each other. A blocking member is provided at the extraction port to block it. The lower isolator and the blocking member can block or release the liquid outlet as the lower cover moves.

[0007] As a further improvement of this utility model, the upper isolation member is hollow cone-shaped, with the cone tip facing the lower isolation member, and the liquid outlet is located at the cone tip.

[0008] As a further improvement of this utility model, the shielding component is a silicone sleeve, which covers the extraction port.

[0009] As a further improvement of this utility model, the lower isolation member is hollow cone-shaped, with the cone tip facing the upper isolation member, and the extraction port is located at the cone tip.

[0010] As a further improvement of this utility model, an extension section is provided at the cone tip of the lower isolation member. The extension section is columnar, and the extraction port is provided in the extension section.

[0011] As a further improvement of this utility model, the side of the silicone sheath near the liquid outlet is an arc surface.

[0012] As a further improvement of this utility model, the lower cover is threadedly connected to the tube body.

[0013] As a further improvement of this utility model, a support extending into the tube body is provided on the lower cover, the support surrounds the through hole, and a lower cover rubber plug is provided on the support.

[0014] As a further improvement of this utility model, the lower cover rubber plug is located inside the hollow cone of the lower isolation member.

[0015] As a further improvement of this utility model, an aluminum foil sheet is provided on the lower cover, and the aluminum foil sheet blocks the through hole.

[0016] The beneficial effects of this utility model are as follows:

[0017] With the above structure, only one centrifugation is required in the preparation of platelet-rich plasma. The movement of the lower cap away from the tube can completely separate red blood cells from platelet-rich plasma, avoiding the presence of red blood cells in the platelet-rich plasma. The structure is simple, the operation is convenient, and the separation and extraction efficiency and purity are improved. Attached Figure Description

[0018] Figure 1 This is a schematic diagram of the overall structure of a platelet-rich plasma preparation device;

[0019] Figure 2 This is a schematic diagram of the internal structure of a platelet-rich plasma (PRP) generator.

[0020] Wherein: 1-tube body, 2-upper cover, 201-injection rubber stopper, 202-protruding ridge, 3-lower cover, 301-lower cover plate, 302-lower cover rubber stopper, 303-enclosing plate, 304-support, 305-annular support plate, 306-through hole, 4-upper isolation element, 401-liquid outlet, 5-lower isolation element, 501-extraction port, 502-extension section, 6-silicone sheath, 7-aluminum foil paper, 8-upper cavity, 9-dispensing chamber, 10-extraction channel. Detailed Implementation

[0021] The present invention will now be described in detail with reference to the specific embodiments shown in the accompanying drawings. However, these embodiments do not limit the present invention, and any structural, methodological, or functional modifications made by those skilled in the art based on these embodiments are included within the protection scope of the present invention.

[0022] If the description of this utility model involves directions (e.g., up, down, left, right, front, back, outside, inside, etc.), then the directions involved need to be defined. For example, "To clearly express the position and direction described in this utility model, the operator of the instrument is used as a reference, the end closer to the operator is the proximal end, and the end farther from the operator is the distal end." Or, the paper can be used as a reference. Of course, if the positional relationship between the two is defined by mutual reference in the subsequent description, then this definition is not required.

[0023] A platelet-rich plasma (PRP) generator, such as Figures 1-2As shown, the device includes an upper cover 2, a tube body 1, and a lower cover 3 arranged sequentially from top to bottom. An injection port is provided on the upper cover 2, and a through hole 306 is provided on the lower cover 3. The lower cover 3 can move closer to or away from the tube body 1 along its axis. An upper separator 4 and a lower separator 5 are arranged sequentially inside the tube body 1. The upper separator 4 extends along the inner wall of the tube body 1 towards its center, dividing the interior of the tube body 1 into an upper cavity 8 and a lower cavity. A syringe needle can be inserted into the injection port to inject blood into the upper cavity 8. After centrifugation, the blood will separate into two layers: a platelet-poor plasma layer and a platelet-rich plasma layer, from top to bottom. The upper isolator 4 has a liquid outlet 401, and the blood tends to flow towards the liquid outlet 401 under the action of gravity. The lower isolator 5 is set on the lower cover 3 and can move closer to or away from the upper isolator 4 with the lower cover 3. The lower isolator 5 divides the lower cavity into a liquid distribution chamber 9 and an extraction channel 10. An extraction port 501 is set on the lower isolator 5. The through hole 306, the extraction port 501 and the liquid outlet 401 correspond to each other. A blocking member is set at the extraction port 501 to block the extraction port 501. The lower isolator 5 and the blocking member can block or release the liquid outlet 401 as the lower cover 3 moves. That is, when the lower cover 3 is closest to the tube body 1, the lower isolator 5 and the shielding member block the outlet 401, and the platelet-poor plasma, platelet-rich plasma and red blood cells remain stationary in the upper cavity 8. When the lower cover 3 moves away from the tube body 1, the lower isolator 5 and the shielding member move away from the outlet 401, the outlet 401 opens, and the red blood cells flow out of the outlet 401 under the action of gravity and enter the dispensing chamber 9. When there are no red blood cells in the upper cavity 8, the syringe needle can be inserted into the through hole 306 and pass through the extraction channel 10, the extraction port 501, the shielding member and the outlet 401 in sequence to enter the upper cavity 8.

[0024] In one embodiment of this utility model, the upper isolation member 4 is hollow cone-shaped, with the cone tip facing the lower isolation member 5, and the liquid outlet 401 is located at the cone tip. Preferably, to facilitate blood flow, the upper isolation member 4 is hollow cone-shaped.

[0025] In one embodiment of this utility model, the shielding component is a silicone sleeve 6, which covers the extraction port 501. This facilitates the insertion of the syringe needle through the silicone sleeve 6 while preventing hard contact with the upper isolator 4. Furthermore, the side of the silicone sleeve 6 near the outlet 401 is an arc surface. The arc surface design provides better sealing. Additionally, when the outlet 401 is open, the arc surface structure guides the flow of red blood cells to the top of the silicone sleeve 6, directing them into the dispensing chamber 9.

[0026] In one embodiment of this utility model, the lower isolator 5 is hollow conical, with the tip of the cone facing the upper isolator 4. The extraction port 501 is located at the tip of the cone, and the liquid outlet 401 is coaxially arranged with the extraction port 501. Preferably, to facilitate blood flow, the lower isolator 5 is hollow conical. Furthermore, since the extraction port 501 is conical, the conventionally shaped silicone sleeve 6 is prone to detachment or slippage during installation. Therefore, to better install the silicone sleeve 6, an extension section 502 is provided at the tip of the lower isolator 5. The extension section 502 is cylindrical, and the extraction port 501 is located on the extension section 502. This design changes the end of the lower isolator 5 from conical to cylindrical, facilitating the installation of the silicone sleeve 6 and preventing it from detaching. Preferably, the extension section 502 is cylindrical.

[0027] In one embodiment of this utility model, the lower cover 3 is threadedly connected to the tube body 1. Specifically, the lower cover 3 includes a lower cover plate 301, a lower cover rubber plug 302 disposed on the lower cover plate 301, and a circumferential surrounding plate 303 extending from the lower cover plate 301 toward the tube body 1. The surrounding plate 303 is threadedly connected to the tube body 1, so that by screwing the surrounding plate 303, the lower cover plate 301 can move closer to or further away from the tube body 1. The lower isolation plate and the through hole 306 are disposed on the lower cover plate 301, and the through hole 306, the extraction port 501, and the liquid outlet 401 are preferably coaxially arranged.

[0028] Furthermore, a support extending into the tube body 1 is provided on the lower cover 3, the support surrounding the through hole 306, and a lower cover rubber plug 302 is provided on the support. Preferably, the support includes a bracket 304 and an annular support plate 305 mounted on the bracket 304. Both the bracket 304 and the annular support plate 305 are arranged around the through hole 306. Here, "surrounding" means that, viewed from the projection on the lower cover plate 301, the circle containing the through hole 306 is located within the circle containing the bracket 304 / annular support plate 305. The lower cover rubber plug 302 has an I-shaped cross-section, and the narrowest radial section of the lower cover rubber plug 302 cooperates with the annular support plate 305, that is, the lower cover rubber plug 302 is stuck on the annular support plate 305. This structural design allows the annular support plate 305 to act as a blocking and limiting force in both directions during the insertion and removal of the syringe needle from the lower cover rubber plug 302, preventing the lower cover rubber plug 302 from shifting. Specifically, the lower cover rubber plug 302 is disposed at the center of the lower cover plate 301.

[0029] Furthermore, the lower cover rubber stopper 302 is located inside the hollow cone of the lower isolation member 5. The lower isolation member 5, the lower cover plate 301, and the lower cover rubber stopper 302 form the extraction channel 10. The lower isolation member 5 and the lower cover rubber stopper 302 are coaxially arranged, so that the centers of the liquid outlet 401, the extraction port 501, and the lower cover rubber stopper 302 are located on a line.

[0030] As an embodiment of this utility model, an aluminum foil sheet 7 is provided on the lower cover plate 301. The aluminum foil sheet 7 blocks the through hole 306, that is, blocks the lower cover rubber plug 302. The blocking of the aluminum foil sheet 7 can ensure that the connection between the lower cover rubber plug 302 and the lower cover 3 is sterile.

[0031] In one embodiment of this utility model, the upper cover 2 is threadedly connected to the tube body 1, and an injection plug 201 is provided at the injection port, allowing the syringe needle to enter the upper cavity 8 by inserting into the injection plug 201. Furthermore, several protruding ridges 202 are provided on the outer surface of the upper cover 2, facilitating gripping and screwing of the upper cover 2. Similarly, a similar structure is provided on the lower cover 3.

[0032] The working principle of this utility model is as follows:

[0033] Before use, the lower cover 3 is screwed tightly onto the tube body 1, the lower cover plate 301 is at the closest distance to the tube body 1, and the silicone sleeve 6 blocks the liquid outlet 401.

[0034] After the syringe draws human blood, the syringe needle is inserted into the tube 1 through the injection stopper 201, and the blood is injected into the upper cavity 8. The platelet-rich plasma preparer is placed in a centrifuge for centrifugation. The centrifuged blood is divided into layers in the upper cavity 8, and each layer from top to bottom is platelet-poor plasma, platelet-rich plasma, and red blood cells.

[0035] Gently twist the lower cover 3. The lower cover plate 301 moves the lower isolation piece 5 and the silicone sleeve 6 away from the outlet 401, and the outlet 401 opens. The red blood cells at the bottom layer flow into the dispensing chamber 9 through the outlet 401. After the red blood cells are completely released, twist the lower cover 3 in the opposite direction. The lower cover plate 301 moves the lower isolation piece 5 and the silicone sleeve 6 closer to the outlet 401. The silicone sleeve 6 seals the outlet 401. At this time, the bottom layer in the upper cavity 8 is platelet-rich plasma.

[0036] Tear off the aluminum foil 7 at the bottom of the lower cover 3, insert the needle of the new syringe into the extraction channel 10 through the rubber stopper 302 of the lower cover, pass through the silicone sleeve 6 at the extraction port 501 and the liquid outlet 401 to enter the platelet-rich plasma layer, and then extract platelet-rich plasma.

[0037] The platelet-rich plasma (PRP) preparer provided by this invention only requires one centrifugation during the preparation process. By simply unscrewing the lower cap, red blood cells can be completely separated from PRP, avoiding the presence of red blood cells in the PRP and preventing inflammatory reactions in patients during subsequent use. The device has a simple structure, is easy to operate, and improves the efficiency and purity of separation and extraction.

[0038] It should be understood that although this specification describes embodiments, not every embodiment contains only one independent technical solution. This way of describing the specification is only for clarity. Those skilled in the art should regard the specification as a whole. The technical solutions in each embodiment can also be appropriately combined to form other embodiments that can be understood by those skilled in the art.

[0039] The detailed descriptions listed above are merely specific descriptions of feasible implementation methods of this utility model, and are not intended to limit the scope of protection of this utility model. All equivalent implementation methods or modifications made without departing from the spirit of this utility model should be included within the scope of protection of this utility model.

Claims

1. A platelet-rich plasma (PRP) generator, characterized in that: The device includes an upper cover (2), a tube body (1), and a lower cover (3) arranged in sequence. An injection port is provided on the upper cover (2), and a through hole (306) is provided on the lower cover (3). The lower cover (3) can move closer to or further away from the tube body (1) along its axis. An upper partition (4) and a lower partition (5) are provided inside the tube body (1). The upper partition (4) divides the interior of the tube body (1) into an upper cavity (8) and a lower cavity. An outlet (401) is provided on the upper partition (4). The isolation member (5) is set on the lower cover (3) and can move with the lower cover (3). The lower isolation member (5) divides the lower cavity into a liquid distribution chamber (9) and an extraction channel (10). An extraction port (501) is provided on the lower isolation member (5). The through hole (306), the extraction port (501) and the liquid outlet (401) correspond to each other. A blocking member is provided at the extraction port (501) to block the extraction port (501). The lower isolation member (5) and the blocking member can block or release the liquid outlet (401) as the lower cover (3) moves.

2. The platelet-rich plasma preparation device according to claim 1, characterized in that: The upper isolation member (4) is hollow cone-shaped, with the cone tip facing the lower isolation member (5), and the liquid outlet (401) is located at the cone tip.

3. The platelet-rich plasma preparation device according to claim 1, characterized in that: The shielding component is a silicone sleeve (6), which covers the extraction port (501).

4. The platelet-rich plasma preparation device according to claim 3, characterized in that: The lower isolation member (5) is hollow cone-shaped, with the cone tip facing the upper isolation member (4), and the extraction port (501) is located at the cone tip.

5. The platelet-rich plasma preparation device according to claim 4, characterized in that: An extension section (502) is provided at the cone tip of the lower isolation member (5), the extension section (502) is columnar, and the extraction port (501) is provided on the extension section (502).

6. The platelet-rich plasma preparation device according to claim 3, characterized in that: The side of the silicone sheath (6) near the liquid outlet (401) is an arc surface.

7. The platelet-rich plasma preparation device according to claim 1, characterized in that: The lower cover (3) is threadedly connected to the tube body (1).

8. The platelet-rich plasma preparation device according to claim 4, characterized in that: A support extending into the tube body (1) is provided on the lower cover (3), the support surrounds the through hole (306), and a lower cover rubber plug (302) is provided on the support.

9. The platelet-rich plasma preparation device according to claim 8, characterized in that: The lower cover rubber plug (302) is located in the hollow cone of the lower isolation member (5).

10. The platelet-rich plasma preparation device according to claim 1, characterized in that: An aluminum foil sheet (7) is provided on the lower cover (3), and the aluminum foil sheet (7) covers the through hole (306).

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