An assisted egg collection device

Abstract

The utility model discloses an auxiliary pick -up device, including pick -up dish, first screen, second screen and waste liquid storage bucket, wherein the aperture of first screen is greater than the aperture of second screen, first screen includes connecting ring and screen A, and the connecting ring middle fixed connection screen A, second screen includes connecting cylinder and screen B, wherein the connecting cylinder inside lower position fixed connection screen B, through the mutual cooperation annular convex and annular gap in proper order pick -up dish, connecting ring, connecting cylinder, waste liquid storage barrel can be detachably connected together. The utility model discloses through the cooperation of first screen and second screen of different aperture, can effectively filter blood and impurity, and the quick enrichment egg crown hillock cell compound reduces the ova omission, promotes the pick -up efficiency and accuracy, and simultaneously, the device each component can be quickly disassembled and assembled, is convenient to operate and has improved the overall stability and convenience, provides more efficient, reliable pick -up means for laboratory technician.

Description

Technical Field

[0001] This utility model relates to the field of human assisted reproductive technology, specifically to an egg-collecting device. Background Technology

[0002] In assisted reproductive technology, oocyte retrieval is a crucial step. The oocyte retrieval procedure is as follows: Under transvaginal ultrasound guidance, the clinician uses a needle to puncture the follicles and obtain follicular fluid, which is then given to laboratory personnel. The laboratory personnel immediately pour the follicular fluid into a 60mm dish and quickly locate the cumulus coronatum cell complex under a stereomicroscope. The complex is then picked up using a Pasteur tube and transferred to a culture dish. Because oocytes are sensitive to temperature, studies have shown that prolonged exposure to temperatures below 37 degrees Celsius can affect subsequent cell division. The number of oocytes retrieved is closely related to the live birth rate, especially for patients with few follicles. Each oocyte is crucial to the success of the treatment outcome. Therefore, the entire oocyte retrieval process must be fast and precise to avoid prolonged exposure of oocytes to air, which could affect their subsequent developmental potential, and to prevent oocyte loss, thus maximizing the number of oocytes retrieved.

[0003] During egg retrieval, doctors can quickly aspirate follicles, typically completing the puncture of all follicles in a patient with a normal ovarian response within about 5 minutes. This places high demands on laboratory technicians, as accurately and quickly retrieving all eggs from the follicular fluid remains a challenge. Currently, egg retrieval involves pouring the follicular fluid into a 60mm or 100mm dish, relying on the technician to observe the eggs under a microscope before collection. However, the follicular fluid is often mixed with blood, resulting in a dark red color, requiring the technician to carefully observe it circle by circle under the microscope. In some patients with many follicles, approximately 100ml of follicular fluid can be aspirated, which inevitably increases the retrieval time. Therefore, the retrieval time is largely controlled by the technician's skill level. Furthermore, if too much follicular fluid is poured into the dish, it can lead to unclear microscopic observation, especially for eggs with fewer outer cumulus cells, making them prone to being missed. Utility Model Content

[0004] To address the shortcomings of current egg retrieval methods, such as missed eggs or retrieval speed that cannot keep up with the speed of follicle aspiration, this invention provides a device that can assist workers in quickly and accurately retrieving eggs.

[0005] To achieve the above objectives, the technical solution of this utility model is as follows:

[0006] An auxiliary egg-collecting device includes an egg-collecting dish, a first screen, a second screen, and a waste liquid storage tank. The aperture of the first screen is larger than that of the second screen. The first screen includes a connecting ring and a screen A, with screen A fixedly connected in the middle of the connecting ring. The second screen includes a connecting cylinder and a screen B, with screen B fixedly connected in the lower part of the connecting cylinder. The top and bottom of the connecting ring and the bottom of the connecting cylinder are respectively provided with annular protrusions. The top of the egg-collecting dish, the top of the connecting cylinder, and the top of the waste liquid storage tank are respectively provided with annular notches that mate with the annular protrusions. The egg-collecting dish, the connecting ring, the connecting cylinder, and the waste liquid storage tank are detachably connected together in sequence through the mating annular protrusions and annular notches.

[0007] In use, first remove the egg collection dish, add the in vitro egg collection solution to the dish, then pour the follicular fluid directly into the first screen. Next, rinse with follicular flushing solution, trapping large blood clots on the first screen. The filtered liquid enters the second screen and is rinsed there. At this point, the cumulus ovalis cell complex is trapped on the second screen, while blood cells, scattered granulosa cells, other small particles, blood, and follicular fluid fall into the waste container. Then, remove the first screen and place the second screen back into the egg collection dish, immersing the oocytes on the second screen in the in vitro egg collection solution. Under a stereomicroscope, quickly pick up the cumulus ovalis cell complex from the screen and place it in an incubator for in vitro culture. This completes the egg collection operation. The components can be quickly aligned and connected via annular protrusions and notches. During use, align the annular notch with the annular protrusion and press down to achieve a stable connection, effectively improving assembly efficiency and enhancing the overall stability of the device, preventing liquid spillage or screen displacement due to shaking during filtration.

[0008] Furthermore, the egg-collecting dish has a limiting block A on its side, the connecting ring has a handle A on its side with a limiting block B on the bottom surface of the handle A, the connecting cylinder has a handle B on its side, and the waste liquid storage tank has a limiting block C on its side. The handle A is engaged with the limiting block A of the egg-collecting dish via a snap-fit ​​assembly A, and the limiting block B of the handle A is engaged with the handle B of the connecting cylinder via a snap-fit ​​assembly B. The handle B is engaged with the limiting block C of the waste liquid storage tank via a snap-fit ​​assembly C. Through the cooperation of snap-fit ​​assemblies A, B, and C, the egg-collecting dish, the first screen, the second screen, and the waste liquid storage tank can be quickly connected and disassembled, making operation simple and the structure stable.

[0009] Furthermore, the latching assembly A includes a protrusion A on the top surface of the handle A, and the limiting block A has a limiting groove A that mates with the protrusion A; the latching assembly B includes a protrusion B on the top surface of the handle B, and the limiting block B has a limiting groove B that mates with the protrusion B; the latching assembly C includes a protrusion C on the bottom surface of the handle B, and the limiting block C has a limiting groove C that mates with the protrusion C. By setting the mating structure of protrusions and limiting grooves on each component, the connection between the egg collection dish, the first screen, the second screen, and the waste liquid storage tank becomes simpler and more intuitive. During operation, only alignment and pressing are required to achieve quick locking, improving assembly efficiency and structural stability, and enhancing practicality.

[0010] Furthermore, the protrusion C has the same shape as the protrusion A, and the protrusion C can engage with the limiting slot A. The engagement of the protrusion C with the limiting slot A achieves a stable and rapid connection between the second screen and the egg collection dish, allowing the second screen to be stably placed in the egg collection dish during the egg collection process, facilitating accurate and rapid egg collection.

[0011] Furthermore, the first screen has an aperture of 355 μm, and the second screen has an aperture of 100 μm. The first screen, with an aperture of 355 μm (45 mesh), can filter out blood clots and other large tissues. The diameter of the human cumulus ovalis cell complex is approximately 200-300 μm, and in rare cases, naked eggs without cumulus ovalis cells may be present, with a diameter of 120-150 μm. The second screen, with an aperture of 100 μm (140 mesh), can filter out small molecular impurities, such as blood cells and scattered granulosa cells. After filtration, the second screen retains the cumulus ovalis cell complex. The combined use of the two screens can retain the oocytes that need to be picked up, facilitating subsequent oocyte retrieval operations.

[0012] Furthermore, the inner side of the egg collection dish features a grooved structure to accommodate the second filter. During use, the second filter containing the cumulus ovalis cell complex is aligned with the groove and placed inside, achieving rapid positioning and fixation. This prevents the filter from shaking or tilting, which could affect operational stability. The grooved structure on the inner side of the egg collection dish ensures the second filter is securely embedded in the dish, guaranteeing a tight connection and accurate positioning. This improves the efficiency and safety of egg collection while reducing the risk of liquid spillage.

[0013] When using,

[0014] Compared with the prior art, the present invention has the following advantages and beneficial effects:

[0015] 1. This invention, through the combination of a first screen and a second screen with different pore sizes, can effectively filter blood and impurities, rapidly enrich the cumulus cell complex, reduce oocyte loss, and improve oocyte retrieval efficiency and accuracy. At the same time, the various components of the device can be quickly disassembled and assembled, which is convenient for operation and improves the overall stability and convenience, providing laboratory technicians with a more efficient and reliable oocyte retrieval method.

[0016] 2. This utility model enhances the connection stability between the second screen and the egg collection dish through the compatible design of the protrusion C and the limiting groove A, which facilitates accurate egg collection; the first screen intercepts large particles such as blood clots, while the second screen retains 200-300μm cumulus cell complex and 120-150μm naked eggs, while filtering out tiny impurities such as blood cells, thus reducing the search range under the microscope and improving egg collection efficiency and accuracy. Attached Figure Description

[0017] Figure 1 This is a schematic diagram of the overall structure of this utility model.

[0018] Figure 2 This is a cross-sectional view of the overall structure of this utility model.

[0019] Figure 3 This is a schematic diagram illustrating the combined use of the second sieve and the egg-collecting dish of this utility model.

[0020] Figure 4 This is a top view schematic diagram of the first and second screens of this utility model.

[0021] Attached image labels:

[0022] Egg collection dish—1, First sieve—2, Handle A—21, Connecting ring—22, Sieves A—23, Second sieve—3, Handle B—31, Connecting cylinder—32, Sieves B—33, Buckling assembly A—4, Protrusion A—41, Connecting block A—42, Buckling assembly B—5, Protrusion B—51, Connecting block B—52, Buckling assembly C—6, Protrusion C—61, Connecting block C—62, Waste liquid storage tank—7, Annular protrusion—81, Annular notch—82. Detailed Implementation

[0023] The present invention will be further described below with reference to the accompanying drawings.

[0024] Example 1: An auxiliary egg-collecting device includes an egg-collecting dish 1, a first screen 2, a second screen 3, and a waste liquid storage tank 7, wherein the aperture of the first screen 2 is larger than the aperture of the second screen 3; the first screen 2 includes a connecting ring 22 and a screen A23, and the screen A23 is fixedly connected in the middle of the connecting ring 22; the second screen 3 includes a connecting cylinder 32 and a screen B33, wherein the screen B33 is fixedly connected in the lower part of the connecting cylinder 32; the top and bottom of the connecting ring 22 and the bottom of the connecting cylinder 32 are respectively provided with annular protrusions, and the top of the egg-collecting dish 1, the top of the connecting cylinder 32, and the top of the waste liquid storage tank 7 are respectively provided with annular notches 82 that cooperate with the annular protrusions 81. The egg-collecting dish 1, the connecting ring 22, the connecting cylinder 32, and the waste liquid storage tank 7 are detachably connected together through the mutually cooperating annular protrusions 81 and annular notches 82.

[0025] During use, first remove the oocyte collection dish 1, add the in vitro oocyte collection solution to the oocyte collection dish 1, and then pour the follicular fluid directly into the first screen 2. Then, use the follicular flushing solution to rinse, so that large blood clots are trapped on the first screen 2. The filtered liquid enters the second screen 3 and is rinsed in the second screen 3. At this time, the cumulus ovalis cell complex is trapped on the second screen 3, while blood cells, scattered granulosa cells and other small substances, blood and follicular fluid fall into the waste liquid bucket. Then, remove the first screen 2 and put the second screen 3 back into the oocyte collection dish 1, so that the oocytes on the second screen 3 are immersed in the in vitro oocyte collection solution. Then, under a stereomicroscope, quickly pick up the cumulus ovalis cell complex in the screen and put it into an incubator for in vitro culture. This completes the oocyte collection operation. The in vitro oocyte collection solution can be products such as SAGE Oocyte Retrieval Medium or Origio Oocyte Collection Medium, and the follicular flushing solution can be products such as SAGE Follicular Fluid or G-MOPS™. The components can be quickly aligned and connected through the annular protrusion 81 and the annular notch 82. When in use, the annular notch 82 and the annular notch 81 are aligned and pressed down to achieve a stable connection. This can effectively improve assembly efficiency, enhance the overall stability of the device, and prevent liquid from overflowing or screen from shifting due to shaking during the filtration process.

[0026] Example 2: The difference from Example 1 is that the egg collection dish 1 has a limiting block A42 on its side, the connecting ring 22 has a handle A21 on its side with a limiting block B52 on the bottom surface of the handle A21, the connecting cylinder 32 has a handle B31 on its side, and the waste liquid storage tank 7 has a limiting block C62 on its side. The handle A21 is engaged with the limiting block A42 of the egg collection dish 1 via a snap-fit ​​assembly A4, and the limiting block B52 of the handle A21 is engaged with the handle B31 of the connecting cylinder 32 via a snap-fit ​​assembly B5. The handle B31 is engaged with the limiting block C62 of the waste liquid storage tank 7 via a snap-fit ​​assembly C6. Through the cooperation of snap-fit ​​assemblies A4, B5, and C6, the egg collection dish 1, the first screen 2, the second screen 3, and the waste liquid storage tank 7 can be quickly connected and disassembled, making operation simple and the structure stable.

[0027] The first screen 2 has a pore size of 355 μm, and the second screen 3 has a pore size of 100 μm. The first screen 2, with a pore size of 355 μm (45 mesh), can filter out blood clots and other large tissues. The diameter of the human cumulus ovalis cell complex is approximately 200-300 μm. In rare cases, naked eggs without cumulus ovalis cells may be present, with a diameter of 120-150 μm. The second screen 3, with a pore size of 100 μm (140 mesh), can filter out small molecule impurities, such as blood cells and scattered granulosa cells. After filtration, the second screen retains the cumulus ovalis cell complex. The combined use of the two screens can retain the oocytes that need to be picked up, facilitating subsequent oocyte retrieval operations.

[0028] Example 3: The difference from Example 2 is that the latching assembly A4 includes a protrusion A41 on the top surface of the handle A21, and the limiting block A42 has a limiting groove A that mates with the protrusion A41; the latching assembly B5 includes a protrusion B51 on the top surface of the handle B31, and the limiting block B52 has a limiting groove B that mates with the protrusion B51; the latching assembly C6 includes a protrusion C61 on the bottom surface of the handle B31, and the limiting block C62 has a limiting groove C that mates with the protrusion C61. By setting the protrusion and limiting groove mating structure on each component, the connection between the egg collection dish 1, the first screen 2, the second screen 3, and the waste liquid storage tank 7 is simpler and more intuitive. During operation, only alignment and pressing are needed to achieve quick locking, improving assembly efficiency and structural stability, and enhancing practicality.

[0029] The protrusion C61 has the same shape as the protrusion A41, and the protrusion C61 can engage with the limiting slot A. The engagement of the protrusion C61 with the limiting slot A achieves a stable and rapid connection between the second screen 3 and the egg collection dish 1, so that the second screen 3 can be stably placed in the egg collection dish 1 during the egg collection process, which facilitates accurate and rapid egg collection.

[0030] The inner side of the egg collection dish 1 has a groove structure that mates with the second filter 3. During use, the second filter 3, containing the cumulus ovalis cell complex, is aligned with the groove and placed inside, achieving rapid positioning and fixation. This prevents the second filter 3 from shaking or tilting, which could affect operational stability. The groove structure on the inner side of the egg collection dish 1, which mates with the second filter 3, ensures that the second filter 3 is securely embedded in the egg collection dish 1, guaranteeing a tight connection and accurate positioning. This improves the efficiency and safety of egg collection while reducing the risk of liquid spillage.

[0031] Numerous specific details are set forth in this specification. However, it will be understood that embodiments of this invention may be practiced without these specific details. In some instances, well-known methods, structures, and techniques have not been shown in detail so as not to obscure the understanding of this specification.

[0032] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of this utility model, and not to limit it. Although the utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some or all of the technical features. Such modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of this utility model, and they should all be covered within the scope of the claims and specification of this utility model.

Claims

1. An auxiliary egg-collecting device, characterized in that: The system includes an egg collection dish (1), a first screen (2), a second screen (3), and a waste liquid storage tank (7), wherein the aperture of the first screen (2) is larger than that of the second screen (3); the first screen (2) includes a connecting ring (22) and a screen A (23), and the screen A (23) is fixedly connected in the middle of the connecting ring (22); the second screen (3) includes a connecting cylinder (32) and a screen B (33), wherein the screen B (33) is fixedly connected in the lower part of the connecting cylinder (32); The top and bottom of the connecting ring (22) and the bottom of the connecting cylinder (32) are respectively provided with annular protrusions (81). The top of the egg collection dish (1), the connecting cylinder (32) and the top of the waste liquid storage tank (7) are respectively provided with annular notches (82) that cooperate with the annular protrusions (81). The egg collection dish (1), the connecting ring (22), the connecting cylinder (32) and the waste liquid storage tank (7) are detachably connected together through the mutually cooperating annular protrusions (81) and annular notches (82).

2. The auxiliary egg-collecting device as described in claim 1, characterized in that: The egg collection dish (1) has a limiting block A (42) on its side, the connecting ring (22) has a handle A (21) on its side and a limiting block B (52) on the bottom surface of the handle A (21), the connecting cylinder (32) has a handle B (31) on its side, and the waste liquid storage tank (7) has a limiting block C (62) on its side; the handle A (21) is engaged with the limiting block A (42) of the egg collection dish (1) by a snap fastener A (4), and the limiting block B (52) of the handle A (21) is engaged with the handle B (31) of the connecting cylinder (32) by a snap fastener B (5), and the handle B (31) is engaged with the limiting block C (62) of the waste liquid storage tank (7) by a snap fastener C (6).

3. The auxiliary egg-collecting device as described in claim 2, characterized in that: The buckle assembly A (4) includes a protrusion A (41) disposed on the top surface of the handle A (21), and the limiting block A (42) is provided with a limiting groove A that cooperates with the protrusion A (41); the buckle assembly B (5) includes a protrusion B (51) disposed on the top surface of the handle B (31), and the limiting block B (52) is provided with a limiting groove B that cooperates with the protrusion B (51); the buckle assembly C (6) includes a protrusion C (61) disposed on the bottom surface of the handle B (31), and the limiting block C (62) is provided with a limiting groove C that cooperates with the protrusion C (61).

4. The auxiliary egg-collecting device as described in claim 3, characterized in that: The protrusion C (61) has the same shape as the protrusion A (41), and the protrusion C (61) can be engaged with the limiting slot A.

5. The egg-collecting auxiliary device as described in claim 1, characterized in that: The aperture of the first screen (2) is 355 μm, and the aperture of the second screen (3) is 100 μm.

6. The auxiliary egg-collecting device as described in claim 1, characterized in that: The inner side of the egg collection dish (1) has a groove structure that matches the second filter.

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