A polymer micelle detection sampler

By designing an automatic stirring and heat insulation polymer micelle detection sampler, the problem of uneven stirring in existing samplers has been solved, improving detection accuracy and sample stability, and simplifying the operation process.

CN224435875UActive Publication Date: 2026-06-30YANTAI LUYIN PHARM CO LTD

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
YANTAI LUYIN PHARM CO LTD
Filing Date
2025-07-18
Publication Date
2026-06-30

AI Technical Summary

Technical Problem

Existing samplers cannot uniformly agitate polymer micelles, resulting in insufficient sample representativeness and affecting the quantitative accuracy of chromatographic analysis.

Method used

A polymer micelle detection sampler including a sampling mechanism and a storage mechanism was designed. It uses a drive motor to provide power for automatic stirring, and combines a one-way valve and a sampling needle made of titanium alloy and polytetrafluoroethylene to ensure uniform dispersion and purity of the sample. The sample bottle is made of double-layer vacuum glass for heat insulation.

Benefits of technology

It achieves uniform dispersion of polymer micelles, improves detection accuracy and sample preservation time, simplifies the operation process, and avoids sample contamination and uneven mixing caused by manual stirring.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN224435875U_ABST
    Figure CN224435875U_ABST
Patent Text Reader

Abstract

This utility model discloses a polymer micelle detection sampler, belonging to the field of sampler technology. This polymer micelle detection sampler includes a sampling mechanism and a storage mechanism. The sampling mechanism includes a sampling cylinder with a piston slidably mounted inside. A push-pull rod is fixedly mounted at the center of one side of the piston, and a handle is fixedly mounted on the bottom side of the sampling cylinder. The storage mechanism includes a connecting seat and a sample bottle. The bottom end of the connecting seat is connected to one side of the upper end of the sampling cylinder. A stirring rod is rotatably connected to one end of the connecting seat. An inlet tube is mounted on one side of the stirring rod at one end of the connecting seat. The sample bottle is sleeved on the outside of the stirring rod, and one end of the sample bottle is threadedly connected to the outside of one end of the connecting seat. A first one-way valve is embedded in one end of the sample bottle. This utility model can effectively improve the practicality of the polymer micelle detection sampler and has high practical value.
Need to check novelty before this filing date? Find Prior Art

Description

Technical Field

[0001] This utility model relates to the field of sampler technology, specifically a polymer micelle detection sampler. Background Technology

[0002] Polymer micelles, as a novel drug carrier or functional material, have attracted much attention in fields such as nanotechnology and biomedicine.

[0003] Based on the above, the inventors have discovered the following problems: During storage, polymer micelles are prone to forming concentration gradients due to gravity settling or Brownian motion imbalance. Existing samplers can only extract the solution from a certain location and cannot stir the micelles evenly, resulting in insufficient sample representativeness. In chromatographic analysis, local high-concentration micelles can also cause chromatographic peak tailing or overload, resulting in large differences in peak area among samples from the same batch, which directly affects the accuracy of quantification.

[0004] Therefore, in view of this, we have studied and improved the existing structure and its shortcomings, and provided a polymer micelle detection sampler in order to achieve a more practical value. Utility Model Content

[0005] The purpose of this invention is to provide a polymer micelle detection sampler to solve the problem mentioned in the background art that the existing samplers can only extract the solution from a certain location and cannot stir the micelles evenly, resulting in insufficient sample representativeness.

[0006] In view of the above problems, the technical solution proposed by this utility model is as follows:

[0007] A polymer micelle detection sampler includes a sampling mechanism and a storage mechanism. The sampling mechanism includes a sampling tube with a piston slidably mounted inside. A push-pull rod is fixedly mounted at the center of one side of the piston, and a handle is fixedly mounted on the bottom side of the sampling tube. The storage mechanism includes a connecting seat and a sample vial. The bottom end of the connecting seat is connected to one side of the upper end of the sampling tube. A stirring rod is rotatably connected to one end of the connecting seat. An inlet tube is mounted on one side of the stirring rod at one end of the connecting seat. The sample vial is sleeved on the outside of the stirring rod, and one end of the sample vial is threadedly connected to the outside of one end of the connecting seat. A first one-way valve is embedded in one end of the sample vial.

[0008] Furthermore, a drive motor is fixedly installed inside the connecting seat, and the output end of the drive motor is connected to the stirring rod for transmission.

[0009] The beneficial effect of adopting the above-mentioned further solution is that the drive motor provides power to the stirring rod, realizes automatic stirring of the sample, ensures uniform dispersion of polymer micelles, avoids sample contamination or uneven mixing caused by manual stirring, and improves detection accuracy.

[0010] Furthermore, the sample vial is made of double-layered vacuum glass.

[0011] The beneficial effect of adopting the above-mentioned further solution is that the sample vials made of double-layer vacuum glass have good heat insulation performance, which can reduce the influence of external temperature on polymer micelle samples, delay sample deterioration, and extend sample preservation time.

[0012] Furthermore, a connecting tube is installed at one end of the sampling tube, a second one-way valve is installed at one end of the connecting tube, and a sampling needle tube is sleeved on one end of the second one-way valve.

[0013] The beneficial effect of adopting the above-mentioned further solution is that when the piston is pulled, the sample can enter the sampling cylinder normally, and when the piston is pushed, the sample will not flow back, and the sampling needle can easily be inserted into the container to extract the sample.

[0014] Furthermore, a third one-way valve is installed at the upper end of the connecting cylinder, and one end of the third one-way valve is connected to the sample injection tube through a pipe.

[0015] The beneficial effect of adopting the above-mentioned further solution is that, with the third one-way valve in conjunction with the injection tube, when the piston is pushed, the sample cannot be discharged from the second one-way valve, but can only enter the injection tube through the pipeline via the third one-way valve, thereby pushing the sample into the sample vial.

[0016] Furthermore, the sampling needle is made of titanium alloy, and the sampling tube is made of polytetrafluoroethylene.

[0017] The advantages of adopting the above-mentioned further solutions are that the titanium alloy sampling needle is corrosion-resistant and has high strength, making it suitable for contacting various polymer micelle samples; the polytetrafluoroethylene sampling tube has good chemical stability, avoiding reaction with the sample and ensuring sample purity.

[0018] Furthermore, an electric telescopic rod is inserted into one side of the upper end of the grip, and the moving end of the electric telescopic rod is fixedly connected to one end of the push-pull rod.

[0019] The beneficial effect of adopting the above-mentioned further solution is that the electric telescopic rod drives the push-pull rod to automatically extend and retract, realizing the automated movement of the piston, replacing manual push-pull, improving the accuracy of sampling, and reducing the intensity of operation.

[0020] Furthermore, a control button is installed on the other side of the upper end of the grip, and the control button is electrically connected to the drive motor and the electric telescopic rod via a wire.

[0021] The beneficial effect of adopting the above-mentioned further solution is that the control button can conveniently control the start and stop of the drive motor and electric telescopic rod, realize the integrated operation of sampling and stirring, simplify the process, and improve the ease of use.

[0022] Compared with the prior art, the beneficial effects of this utility model are as follows: In the sampling mechanism of this polymer micelle detection sampler, pushing the push-pull rod causes the piston to slide inside the sampling cylinder, which can extract polymer micelle samples. The handle is convenient for hand operation. The sample bottle of the storage mechanism is connected to the sampling cylinder through a connecting seat. The sample inlet tube introduces the sample into the sample bottle. The stirring rod can stir the sample to prevent its local concentration from being too high. The first one-way valve prevents sample leakage. After the sample enters the sample bottle, it can expel excess air inside to prevent excessive internal pressure. The whole device realizes the integration of sampling, stirring and storage, improving operation convenience. For ease of use and sample stability, the drive motor provides power to the stirring rod, enabling automatic sample stirring and ensuring uniform dispersion of polymer micelles. This avoids sample contamination or uneven mixing caused by manual stirring, improving detection accuracy. The second one-way valve allows the sample to enter the sampling tube normally when the piston is pulled, and prevents backflow when the piston is pushed. This facilitates the insertion of the sampling needle into the container to extract the sample. The third one-way valve works in conjunction with the injection tube. When the piston is pushed, the sample cannot be discharged from the second one-way valve, but can only enter the injection tube through the third one-way valve, thus pushing the sample into the sample bottle. Attached Figure Description

[0023] Figure 1 This is a three-dimensional structural diagram of the polymer micelle detection sampler disclosed in this embodiment of the present invention. Figure 1 ;

[0024] Figure 2 This is a three-dimensional structural diagram of the polymer micelle detection sampler disclosed in this embodiment of the present invention. Figure 2 ;

[0025] Figure 3 This is a three-dimensional structural diagram of the polymer micelle detection sampler disclosed in this embodiment of the present invention. Figure 3 ;

[0026] Figure 4 This is a partial front cross-sectional view of the sampling cylinder and connecting seat of the polymer micelle detection sampler disclosed in this embodiment of the present invention;

[0027] Figure 5 This is a partial front cross-sectional view of the handle of the polymer micelle detection sampler disclosed in this embodiment of the present invention.

[0028] In the diagram: 1. Sampling mechanism; 101. Sampling cylinder; 102. Push-pull rod; 103. Handle; 104. Control button; 105. Electric telescopic rod; 106. Connecting cylinder; 107. Second one-way valve; 108. Sampling needle; 109. Third one-way valve; 110. Piston; 2. Storage mechanism; 201. Connecting seat; 202. Sample bottle; 203. First one-way valve; 204. Stirring rod; 205. Injection tube; 206. Drive motor. Detailed Implementation

[0029] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0030] Please see Figures 1-5 This utility model provides a technical solution: a polymer micelle detection sampler, including a sampling mechanism 1 and a storage mechanism 2. The sampling mechanism 1 includes a sampling cylinder 101, a piston 110 slidably mounted inside the sampling cylinder 101, a push-pull rod 102 fixedly mounted at the center of one side of the piston 110, and a handle 103 fixedly mounted on the bottom side of the sampling cylinder 101. The storage mechanism 2 includes a connecting seat 201 and a sample bottle 202. The bottom end of the connecting seat 201 is connected to one side of the upper end of the sampling cylinder 101, and a stirring rod 204 is rotatably connected to one end of the connecting seat 201. A sample inlet tube 205 is mounted on one side of the stirring rod 204 at one end of the connecting seat 201. The sample bottle 202 is sleeved on the outside of the stirring rod 204, and one end of the sample bottle 202 is connected to the connecting seat 204. One end of the connector 201 is threaded on the outside, and one end of the sample vial 202 is fitted with a first one-way valve 203. In the sampling mechanism 1, pushing the push-pull rod 102 causes the piston 110 to slide inside the sampling cylinder 101, which can extract polymer micelle samples. The handle 103 facilitates hand operation. The sample vial 202 of the storage mechanism 2 is connected to the sampling cylinder 101 through the connector 201. The sample inlet tube 205 introduces the sample into the sample vial 202. The stirring rod 204 can stir the sample to prevent the local concentration from being too high. The first one-way valve 203 prevents sample leakage. After the sample enters the sample vial 202, it can expel the excess air inside to prevent excessive internal pressure. The whole system realizes the integration of sampling, stirring and storage, improving the convenience of operation and sample stability.

[0031] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0032] Please see Figures 1-5 A drive motor 206 is fixedly installed inside the connecting base 201. The output end of the drive motor 206 is connected to the stirring rod 204. The sample bottle 202 is made of double-layer vacuum glass. A connecting tube 106 is installed at one end of the sampling tube 101. A second one-way valve 107 is installed at one end of the connecting tube 106. A sampling needle tube 108 is sleeved at one end of the second one-way valve 107. A third one-way valve 109 is installed at the upper end of the connecting tube 106. One end of the third one-way valve 109 is connected to the sample injection tube 205 through a pipe. The sampling needle tube 108 is made of titanium alloy, and the sampling tube 101 is made of polytetrafluoroethylene. An electric telescopic rod 105 is inserted into one side of the upper end of the handle 103. The moving end of the electric telescopic rod 105 is fixedly connected to one end of the push-pull rod 102. A control button 104 is installed on the other side of the upper end of the handle 103. The control button 104 is electrically connected to the drive motor 206 and the electric telescopic rod 105 through a wire. The drive motor 206 provides power to the stirring rod 204 to realize automatic stirring of the sample, ensuring uniform dispersion of polymer micelles, avoiding sample contamination or uneven mixing caused by manual stirring, and improving detection accuracy. The sample vial 202 made of double-layer vacuum glass has good heat insulation. The temperature-controlled design reduces the impact of external temperature on polymer micelle samples, delaying sample deterioration and extending sample preservation time. The second one-way valve 107 allows the sample to enter the sampling cylinder 101 normally when the piston 110 is pulled, and prevents backflow when the piston 110 is pushed. The sampling needle 108 easily extends into the container to extract the sample. The third one-way valve 109, in conjunction with the injection tube 205, prevents the sample from exiting through the second one-way valve 107 when the piston 110 is pushed; instead, the sample enters the injection tube 205 through the third one-way valve 109, thus pushing the sample into the sample container. In bottle 202, the titanium alloy sampling needle 108 is corrosion-resistant and high-strength, suitable for contacting various polymer micelle samples; the polytetrafluoroethylene sampling tube 101 has good chemical stability, avoiding reaction with the sample and ensuring sample purity; the electric telescopic rod 105 drives the push-pull rod 102 to automatically extend and retract, realizing the automated movement of the piston 110, replacing manual push-pull, improving the accuracy of sampling volume, and reducing the intensity of operation; the control button 104 can conveniently control the start and stop of the drive motor 206 and the electric telescopic rod 105, realizing integrated operation of sampling and stirring, simplifying the process and improving ease of use.

[0033] Specifically, the working principle of this polymer micelle detection sampler is as follows: During use, the electric telescopic rod 105 is activated by the control button 104, which drives the push-pull rod 102 to pull the piston 110 in the sampling cylinder 101. The sample is extracted using the sampling needle tube 108 and the second one-way valve 107. When the piston 110 is pushed, the sample enters the sample bottle 202 through the third one-way valve 109 and the sample inlet tube 205. The first one-way valve 203 discharges the air in the bottle. The drive motor 206 is activated to drive the stirring rod 204 to stir the sample. The double-layered vacuum glass sample bottle 202 keeps the sample stable. The titanium alloy sampling needle tube 108 and the polytetrafluoroethylene sampling cylinder 101 avoid contamination, realizing automated operation of sampling, transportation, stirring and storage.

[0034] It should be noted that all standard parts used in this application can be purchased from the market, and can be customized according to the description and drawings. The specific connection methods of each part adopt conventional methods such as bolts, rivets, and welding that are mature in the prior art. The machinery, parts and equipment adopt conventional models in the prior art. The control method is automatic control through a controller. The control circuit of the controller can be implemented by simple programming by those skilled in the art and is common knowledge in the field. Furthermore, since this application is mainly used to protect mechanical devices, this application will not explain the control method and circuit connection in detail.

Claims

1. A polymer micelle detection sampler, characterized in that, The system includes a sampling mechanism (1) and a storage mechanism (2). The sampling mechanism (1) includes a sampling cylinder (101), a piston (110) is slidably mounted inside the sampling cylinder (101), a push-pull rod (102) is fixedly mounted at the center of one side of the piston (110), and a handle (103) is fixedly mounted on the bottom side of the sampling cylinder (101). The storage mechanism (2) includes a connecting seat (201) and a sample bottle (202). The connecting seat (201) has a... The bottom end is connected to one side of the upper end of the sampling cylinder (101). One end of the connecting seat (201) is rotatably connected to a stirring rod (204). One end of the connecting seat (201) is located on one side of the stirring rod (204) and an injection tube (205) is installed. The sample bottle (202) is sleeved on the outside of the stirring rod (204), and one end of the sample bottle (202) is threadedly connected to the outside of one end of the connecting seat (201). One end of the sample bottle (202) is embedded with a first one-way valve (203).

2. The polymer micelle detection sampler according to claim 1, characterized in that, The drive motor (206) is fixedly installed inside the connecting seat (201), and the output end of the drive motor (206) is connected to the stirring rod (204) for transmission.

3. The polymer micelle detection sampler according to claim 1, characterized in that, The sample bottle (202) is made of double-layered vacuum glass.

4. The polymer micelle detection sampler according to claim 1, characterized in that, A connecting tube (106) is installed at one end of the sampling tube (101), a second one-way valve (107) is installed at one end of the connecting tube (106), and a sampling needle tube (108) is sleeved at one end of the second one-way valve (107).

5. A polymer micelle detection sampler according to claim 4, characterized in that, A third check valve (109) is installed at the upper end of the connecting cylinder (106), and one end of the third check valve (109) is connected to the injection tube (205) through a pipe.

6. A polymer micelle detection sampler according to claim 4, characterized in that, The sampling needle (108) is made of titanium alloy, and the sampling tube (101) is made of polytetrafluoroethylene.

7. A polymer micelle detection sampler according to claim 1, characterized in that, An electric telescopic rod (105) is inserted into one side of the upper end of the grip (103), and the moving end of the electric telescopic rod (105) is fixedly connected to one end of the push-pull rod (102).

8. A polymer micelle detection sampler according to claim 1, characterized in that, A control button (104) is installed on the other side of the upper end of the grip (103). The control button (104) is electrically connected to the drive motor (206) and the electric telescopic rod (105) via wires.