Liquid chromatograph facilitating quick loading and unloading of reagent bottles

By using a cylinder to drive the mounting plate and elastic components, the reagent bottles for liquid chromatographs can be quickly loaded and unloaded, solving the problems of low automation and wear of infusion tubing, and improving loading and unloading efficiency and sealing reliability.

CN224500536UActive Publication Date: 2026-07-14GUANGDONG MICROCHEM INSPECTION TECH CO LTD

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
GUANGDONG MICROCHEM INSPECTION TECH CO LTD
Filing Date
2025-06-18
Publication Date
2026-07-14

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    Figure CN224500536U_ABST
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Abstract

The utility model relates to liquid chromatograph technical field especially, it relates to a liquid chromatograph convenient to quick loading and unloading reagent bottle. The utility model provides a liquid chromatograph convenient to quick loading and unloading reagent bottle, including liquid chromatograph body, control panel, reagent placing box, baffle and reagent bottle, liquid chromatograph body front side is provided with control panel, liquid chromatograph body top is provided with reagent placing box, reagent placing box inside fixedly connected with multiple baffles, reagent placing box inside places multiple reagent bottles, and the baffle separates reagent bottles. Through the telescopic drive mounting plate up and down movement of the telescopic rod of control cylinder, realize the opening and closing of sealing plug and the plugging of infusion tube, thereby convenient to loading and unloading reagent bottle, improve the degree of automation, and reduce the damage of infusion tube.
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Description

Technical Field

[0001] This utility model relates to the field of liquid chromatography technology, and in particular to a liquid chromatograph that facilitates quick loading and unloading of reagent bottles. Background Technology

[0002] A liquid chromatograph (LC) is an instrument used to separate and analyze the components in a mixture. It uses a liquid as the mobile phase. After the sample is injected, the interaction between the stationary phase and the sample components within the chromatographic column causes different components to move at different speeds within the column, thus achieving separation. The separated components are then detected and analyzed based on their physical or chemical properties by a detector. LC is widely used in chemistry, biology, pharmacy, environmental science, and other fields to analyze trace components in complex samples.

[0003] Patent CN219533033U discloses a liquid chromatograph, including a main body with a liquid storage frame at its upper end. The main body also includes a limiting mechanism on the liquid storage frame for positioning reagent bottles. The limiting mechanism comprises multiple limiting tubes fixedly connected to the liquid storage frame, and two symmetrically arranged limiting rods slidably connected to each limiting tube. A limiting plate is provided at one end of each limiting rod, and an arc-shaped surface is provided at the other end of each limiting plate. While this patent uses a limiting mechanism to position the reagent bottles and prevent accidental tipping and liquid leakage during analysis, thus avoiding damage to the main body, manual loading and unloading of the reagent bottles is still required. This results in low automation, and inaccurate alignment or uneven force during manual operation can easily lead to wear on the infusion tubing connectors, shortening their service life.

[0004] Therefore, a liquid chromatograph that facilitates rapid loading and unloading of reagent bottles is needed. Utility Model Content

[0005] To overcome the shortcomings of current patents, which still require manual loading and unloading of reagent bottles, have a low degree of automation, and are prone to wear and tear on infusion tubing joints due to inaccurate alignment or uneven force, thus shortening their service life, this utility model provides a liquid chromatograph that facilitates quick loading and unloading of reagent bottles.

[0006] The technical solution is as follows: A liquid chromatograph for easy and rapid loading and unloading of reagent bottles includes a liquid chromatograph body, a control panel, a reagent storage box, partitions, and reagent bottles. The control panel is located on the front of the liquid chromatograph body, and the reagent storage box is located on the top of the liquid chromatograph body. Multiple partitions are fixedly connected inside the reagent storage box, and multiple reagent bottles are placed inside the reagent storage box, with the partitions separating the reagent bottles. The system also includes a support plate, a cylinder, a mounting plate, a first guide rod, a slider, a sleeve, a sealing plug, a first elastic element, an infusion tube, and a pipeline pump. The liquid chromatograph body is located at the rear... A support plate is mounted on the side, and a cylinder is mounted on the support plate. A mounting plate is connected to the telescopic rod of the cylinder. A first guide rod is fixedly connected to the support plate. The mounting plate slides on the first guide rod. Multiple grooves are opened on the mounting plate, and sliders are slidably arranged in the grooves. A sleeve is installed through the slider. A sealing plug is slidably arranged at the lower end of the sleeve. A first elastic element is fitted at the lower end of the sleeve. The two ends of the first elastic element are connected to the sleeve and the sealing plug, respectively. Pipeline pumps are installed on both the left and right sides of the liquid chromatograph body. Infusion tubes are connected to the pipeline pumps, and the other end of the infusion tubes extends into the sleeve.

[0007] Preferably, the sleeve also includes a connecting plate, a second guide rod, an arc-shaped pressure plate, and a second elastic element. The connecting plate is fixedly connected to the sleeve, and the second guide rod is slidably arranged on the connecting plate. The lower ends of the two second guide rods are fixedly connected to the arc-shaped pressure plate. The second elastic element is sleeved on the second guide rod, and the two ends of the second elastic element are respectively connected to the connecting plate and the arc-shaped pressure plate.

[0008] Preferably, it also includes a third elastic element and an arc-shaped clamp. Multiple arc-shaped clamps are slidably arranged inside the reagent placement box, and the arc-shaped clamps are connected to the inner wall of the reagent placement box by a third elastic element.

[0009] Preferably, the mounting plate also includes screws and knobs. Multiple screws are threaded onto the mounting plate, with one end of the screw fixedly connected to the slider and the other end of the screw away from the slider fixedly connected to a knob.

[0010] Preferably, the instrument also includes foot pads, with multiple foot pads provided on the liquid chromatograph body.

[0011] Preferably, a pressure gauge is also included, with the pressure gauge installed at the top of the casing.

[0012] Compared with the prior art, this utility model provides a liquid chromatograph that facilitates quick loading and unloading of reagent bottles, and has the following beneficial effects: 1. By controlling the telescopic rod of the cylinder to drive the mounting plate to move up and down, the sealing plug can be opened and closed and the infusion tube can be inserted and removed, thereby facilitating the loading and unloading of reagent bottles, improving the degree of automation, and reducing damage to the infusion tube.

[0013] 2. When the sealing plug contacts the top of the reagent bottle, the second elastic element returns to its original shape, pushing the arc-shaped pressure plate to adjust the position of the reagent bottle so that it is centered, making it easy to accurately insert the infusion tube into the reagent bottle.

[0014] 3. Once the reagent bottle is fully in place, the third elastic element returns to its original shape, pushing the arc-shaped clamp inward to clamp the reagent bottle and prevent it from moving. Attached Figure Description

[0015] Figure 1 This is a three-dimensional structural diagram of the present invention.

[0016] Figure 2 This is a three-dimensional sectional view of the support plate, mounting plate, and infusion tube of this utility model.

[0017] Figure 3 This is a three-dimensional cross-sectional view of the mounting plate, protective cover, and second elastic element of this utility model.

[0018] Figure 4 This is a three-dimensional sectional view of the slider, sleeve, and pressure gauge of this utility model.

[0019] Figure 5 This is a three-dimensional structural diagram of the reagent placement box, partition, and arc-shaped clamp of this utility model.

[0020] Reference numerals: 1. Liquid Chromatograph body; 2. Control panel; 3. Reagent container; 4. Divider; 5. Reagent bottle; 6. Support plate; 7. Cylinder; 8. Mounting plate; 9. First guide rod; 10. Slide groove; 11. Slider; 12. Sleeve; 13. Sealing plug; 14. First elastic element; 15. Infusion tube; 1501. Pipeline pump; 16. Connecting plate; 17. Second guide rod; 18. Arc-shaped pressure plate; 1801. Second elastic element; 19. Third elastic element; 20. Arc-shaped clamp; 21. Screw; 2101. Knob; 22. Foot pad; 23. Pressure gauge. Detailed Implementation

[0021] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0022] Example 1: A liquid chromatograph for easy and rapid loading and unloading of reagent bottles. Please refer to [link to example]. Figures 1-5The system includes a liquid chromatograph body 1, a control panel 2, a reagent storage box 3, partitions 4, and reagent bottles 5. The control panel 2 is located on the front of the liquid chromatograph body 1. The reagent storage box 3 is located on the top of the liquid chromatograph body 1. Four partitions 4 are fixedly connected inside the reagent storage box 3, and four reagent bottles 5 are placed inside the reagent storage box 3, with the partitions 4 separating the reagent bottles 5. A support plate 6 is installed on the rear of the liquid chromatograph body 1. A cylinder 7 is installed on the support plate 6, and a mounting plate 8 is connected to the extension rod of the cylinder 7. A first guide rod 9 is fixedly connected to the support plate 6, and the mounting plate 8 slides on the first guide rod 9. Four grooves 10 are formed on the mounting plate 8, and sliders 11 are slidably installed within the grooves 10. A sleeve 12 is inserted through the slider 11, and a sealing plug 13 is slidably installed at the lower end of the sleeve 12. The lower end of the tube 12 is fitted with a first elastic element 14, and the two ends of the first elastic element 14 are connected to the sleeve 12 and the sealing plug 13 respectively. The liquid chromatograph body 1 is equipped with a pipeline pump 1501 on both the left and right sides. The pipeline pump 1501 is connected to an infusion tube 15, and the other end of the infusion tube 15 extends into the inside of the sleeve 12. The mounting plate 8 is threaded with four screws 21. One end of the screw 21 is fixedly connected to the slider 11, and the end of the screw 21 away from the slider 11 is fixedly connected to a knob 2101. Rotating the screw 21 can adjust the position of the slider 11 to adapt to reagent bottles 5 of different sizes. The liquid chromatograph body 1 is equipped with four feet 22 to support the liquid chromatograph body 1 and maintain stability. The top of the sleeve 12 is equipped with a pressure gauge 23, which displays the internal pressure of the sleeve 12 in real time to ensure the reliability of the seal.

[0023] When the liquid chromatograph needs to be used, first, place the reagent bottle 5 into the reagent placement box 3. Then, start the liquid chromatograph body 1 and cylinder 7, controlling the extension rod of cylinder 7 to retract, pushing the mounting plate 8 downward along the first guide rod 9. At this time, one end of the infusion tube 15 is inserted into the reagent bottle 5. The mounting plate 8 continues to move downward, covering the top of the reagent bottle 5 with the sealing plug 13. The first elastic element 14 presses the sealing plug 13 with its own elasticity, achieving an airtight connection. Subsequently, start the liquid chromatograph body 1 and the pipeline pump 1501. The pipeline pump 1501 pumps the reagent from the reagent bottle 5 into the liquid chromatograph body 1 through the infusion tube 15. When the liquid chromatograph 1 is running, the interaction between the stationary phase and the mobile phase is used to separate different components in the sample. The separated components are detected and analyzed according to their physical or chemical properties by the detector. The detection results are displayed on the control panel 2 for the operator to view and analyze. After the detection is completed, the liquid chromatograph 1 and the pipeline pump 1501 are turned off, the extension rod of the cylinder 7 is extended, and the mounting plate 8 is pushed to move upward along the first guide rod 9, so that the sealing plug 13 is separated from the reagent bottle 5. At the same time, one end of the infusion tube 15 is taken out from the reagent bottle 5. Through the above operation, it is convenient to load and unload the reagent bottle 5, improve the degree of automation, and reduce the damage to the infusion tube 15.

[0024] Example 2: Based on Example 1, please refer to... Figure 3 and Figure 4 A connecting plate 16 is fixedly connected to the sleeve 12. A second guide rod 17 is slidably provided on the connecting plate 16. An arc-shaped pressure plate 18 is fixedly connected to the lower ends of the two second guide rods 17. A second elastic element 1801 is sleeved on the second guide rod 17. The two ends of the second elastic element 1801 are respectively connected to the connecting plate 16 and the arc-shaped pressure plate 18.

[0025] As the mounting plate 8 moves downward, the arc-shaped pressure plate 18 moves downward accordingly and comes into contact with the reagent bottle 5. If the reagent bottle 5 is offset, the reagent bottle 5 will squeeze the arc-shaped pressure plate 18, thereby compressing the second elastic element 1801. When the mounting plate 8 continues to move downward, and the sealing plug 13 comes into contact with the top of the reagent bottle 5, the second elastic element 1801 returns to its original state, pushing the arc-shaped pressure plate 18 to adjust the position of the reagent bottle 5 so that it is centered, making it easy to accurately insert the infusion tube 15 into the reagent bottle 5.

[0026] Please see Figure 5 The reagent placement box 3 has eight arc-shaped clamps 20 that slide inside, and the arc-shaped clamps 20 are connected to the inner wall of the reagent placement box 3 by a third elastic element 19.

[0027] When the reagent bottle 5 is placed into the reagent placement box 3, the reagent bottle 5 squeezes the arc-shaped clamp 20 to move outward and compresses the third elastic element 19. After the reagent bottle 5 is fully placed in place, the third elastic element 19 returns to its original state, pushes the arc-shaped clamp 20 to move inward, and clamps the reagent bottle 5 to prevent it from moving.

[0028] The above description is merely a specific embodiment of this utility model, but the protection scope of this utility model is not limited thereto. Any variations or substitutions that can be easily conceived by those skilled in the art within the technical scope disclosed in this utility model should be included within the protection scope of this utility model. Therefore, the protection scope of this utility model should be determined by the scope of the claims.

Claims

1. A liquid chromatograph for easy and quick loading and unloading of reagent bottles, comprising a liquid chromatograph body (1), a control panel (2), a reagent storage box (3), partitions (4), and reagent bottles (5), wherein the control panel (2) is provided on the front side of the liquid chromatograph body (1), the reagent storage box (3) is provided on the top of the liquid chromatograph body (1), multiple partitions (4) are fixedly connected inside the reagent storage box (3), multiple reagent bottles (5) are placed inside the reagent storage box (3), and the partitions (4) separate the reagent bottles (5), characterized in that: It also includes a support plate (6), a cylinder (7), a mounting plate (8), a first guide rod (9), a slider (11), a sleeve (12), a sealing plug (13), a first elastic element (14), an infusion tube (15), and a pipeline pump (1501). The support plate (6) is installed on the rear side of the liquid chromatograph body (1). The cylinder (7) is installed on the support plate (6). The mounting plate (8) is connected to the telescopic rod of the cylinder (7). The first guide rod (9) is fixedly connected to the support plate (6). The mounting plate (8) slides on the first guide rod (9). Multiple openings are made on the mounting plate (8). A sliding groove (10) is provided in the sliding groove (10), a slider (11) is provided in the sliding groove (10), a sleeve (12) is provided through the slider (11), a sealing plug (13) is provided in the lower end of the sleeve (12), a first elastic element (14) is provided at the lower end of the sleeve (12), and the two ends of the first elastic element (14) are respectively connected to the sleeve (12) and the sealing plug (13). A pipeline pump (1501) is installed on both the left and right sides of the liquid chromatograph body (1), and an infusion tube (15) is connected to the pipeline pump (1501). The other end of the infusion tube (15) extends into the sleeve (12).

2. The liquid chromatograph for easy and rapid loading and unloading of reagent bottles as described in claim 1, characterized in that: It also includes a connecting plate (16), a second guide rod (17), an arc-shaped pressure plate (18), and a second elastic element (1801). The connecting plate (16) is fixedly connected to the sleeve (12). The second guide rod (17) is slidably arranged on the connecting plate (16). The lower ends of the two second guide rods (17) are fixedly connected to the arc-shaped pressure plate (18). The second elastic element (1801) is sleeved on the second guide rod (17). The two ends of the second elastic element (1801) are respectively connected to the connecting plate (16) and the arc-shaped pressure plate (18).

3. The liquid chromatograph for easy and rapid loading and unloading of reagent bottles as described in claim 2, characterized in that: It also includes a third elastic element (19) and an arc-shaped clamp (20). Multiple arc-shaped clamps (20) are slidably arranged inside the reagent placement box (3). The arc-shaped clamps (20) are connected to the inner wall of the reagent placement box (3) by the third elastic element (19).

4. A liquid chromatograph for easy and rapid loading and unloading of reagent bottles as described in claim 3, characterized in that: It also includes a screw (21) and a knob (2101). Multiple screws (21) are threaded on the mounting plate (8). One end of the screw (21) is fixedly connected to the slider (11), and the end of the screw (21) away from the slider (11) is fixedly connected to the knob (2101).

5. A liquid chromatograph for easy and rapid loading and unloading of reagent bottles as described in claim 4, characterized in that: It also includes foot pads (22), and the liquid chromatograph body (1) is provided with multiple foot pads (22).

6. A liquid chromatograph for easy and rapid loading and unloading of reagent bottles as described in claim 5, characterized in that: It also includes a pressure gauge (23), which is installed on the top of the sleeve (12).