Multiplex primer rapid preparation device
By combining the mounting frame mechanism, oscillation mechanism, and centrifugation mechanism, the problems of operational complexity and time consumption in the preparation of multiple primers are solved, and rapid and accurate multiple primer processing is achieved.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- WUHAN KANGSHENG BEITAI BIOLOGICAL TECH CO LTD
- Filing Date
- 2025-09-10
- Publication Date
- 2026-08-04
AI Technical Summary
Existing multiple primer preparation devices require numerous steps to adjust the alignment of the placement plate, are inconvenient to pick up and put back, have slow primer mixing, are time-consuming, and are costly.
The system employs an installation frame mechanism to accelerate primer extraction, an oscillation mechanism to promote rapid fusion, a centrifugation mechanism to achieve efficient processing, and a monitoring component and a power component for precise control.
It enables rapid extraction, fusion, and centrifugation of multiple primers, improving operational efficiency and accuracy while reducing operational complexity and cost.
Smart Images
Figure CN224585932U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of primer design and synthesis optimization technology, and in particular to a device for rapid preparation of multiple primers. Background Technology
[0002] A rapid preparation device for multiple primers is a device that can prepare multiple primers. It has a base plate as a base, a rack on the left that can extract multiple primers at the same time, a device in the middle that can quickly mix primers, and a centrifugation section on the right to assist in processing. The combination of these parts makes the preparation process fast and stable, and is suitable for experimental scenarios that require the rapid preparation of multiple primers.
[0003] This device is mainly used in the laboratory to quickly prepare multiple primers. It allows staff to process multiple primers at the same time, speeds up the preparation process, and ensures accuracy. It reduces the trouble and error of manual operation. Whether it is PCR experiment or other molecular biology experiment, using it to prepare primers can save time and improve efficiency, making the experimental process smoother.
[0004] When picking up and placing primers, the placement plate needs to be adjusted to align them in position. The operation involves many steps, making it difficult to pick up and put back quickly. During fusion, the oscillation intensity and frequency are not ideal, resulting in slow primer mixing and a long time consumption. The device uses many precision parts, leading to a high overall cost. Utility Model Content
[0005] To overcome the above shortcomings, this utility model provides a rapid preparation device for multiple primers, which aims to improve the problems of existing technologies that require adjusting the placement plate to align it, have many operation steps, cannot quickly pick up and put back the primers, and have slow primer mixing and long time consumption.
[0006] To achieve the above objectives, the present invention adopts the following technical solution: a base plate, wherein a shell is provided at the top center of the base plate, and a mounting frame mechanism is provided on the top left side of the base plate. The mounting frame mechanism is used to accelerate the extraction efficiency of multiple primers. An oscillation mechanism is provided inside the shell. The oscillation mechanism is used to accelerate the rapid fusion of multiple primers to shorten the reaction time. A centrifugation mechanism is provided on the top right side of the base plate. The installation frame mechanism includes an elevated frame, the bottom of which is fixedly connected to the top left side of the base plate, and a placement plate is slidably connected to the upper middle part of the elevated frame.
[0007] As a further description of the above technical solution: The oscillation mechanism includes a housing, the outer wall of which is located inside the outer shell. A bearing is fixedly connected to the rear side of the inner side of the housing, and a turbine eccentric shaft is fixedly connected to the front side of the inner side of the bearing. An air intake pipe is connected to the left side of the bottom of the housing, and an exhaust pipe is connected to the right side of the bottom of the housing. A connecting rod is fixedly connected to the top of the housing, and a cover plate is fixedly connected to the top of the outer shell. A swaying body is fixedly connected to the top of the connecting rod.
[0008] As a further description of the above technical solution: The centrifugal mechanism includes an air cover, the bottom of which is located on the top right side of the base plate. A placement groove is engaged with the bottom of the air cover. A rotating shaft is located in the lower middle part of the placement groove. A stabilizing pad is fixedly connected to the outer wall of the rotating shaft. A housing assembly is located on the top right side of the base plate. A closing assembly is located on the rear side of the housing assembly. A power assembly is located inside the housing assembly. A lower cover is fixedly connected to the bottom of the housing assembly.
[0009] As a further description of the above technical solution: The monitoring component includes a scale, the right side of which is fixedly connected to the upper middle part of the outer wall of the pipette. An observation window is provided at the bottom of the pipette, and the right side of the observation window is installed on the lower middle part of the outer wall of the pipette.
[0010] As a further description of the above technical solution: The housing assembly includes a cover, the bottom of which is mounted on the top right side of the base plate. A control terminal is mounted on the upper middle front side of the cover. Two anti-swing pads are fixedly connected to the top front side of the cover. A stabilizing pad is mounted on the inner bottom side of the cover.
[0011] As a further description of the above technical solution: The closure assembly includes two hinges, the bottom of which is mounted on the top rear side of the cover. A cover is fixedly connected to the rear side of the two hinges, and a latch is fixedly connected to the top front side of the cover.
[0012] As a further description of the above technical solution: The power assembly includes a motor, the rear of which is fixedly connected to the inner top front end of the housing. A rotating rod is fixedly connected to the output end of the motor. A belt is fixedly connected to the bottom of the outer wall of the rotating rod. A conveyor rod is rotatably connected to the top rear side of the belt.
[0013] As a further description of the above technical solution: The bottom inner wall of the elevated structure is equipped with multiple threads, and the bottom of the multiple threads is connected to a nut. The top of the swaying body is equipped with a primer storage plate.
[0014] This utility model has the following beneficial effects: 1. In this utility model, the bottom of the elevated frame is fixed to the top left side of the base plate to form a stable support. The placement plate slides and adjusts its position in the upper part of the elevated frame, so that the installation frame mechanism can be adapted to different operating scenarios. Multiple primer extraction components can be set on the placement plate at the same time. With the stable support of the elevated frame and the flexible sliding of the placement plate, the synchronous extraction operation of multiple primers can be realized, thereby improving the extraction efficiency of multiple primers. It can not only carry multiple primer extraction components to complete batch processing through the placement plate, but also rely on the stability of the elevated frame to ensure the stability of the extraction process, reduce operational deviations, and meet the needs of rapid extraction.
[0015] 2. In this utility model, the shell provides an installation space inside the outer shell, the bearing fixes the turbine eccentric shaft so that it can rotate smoothly, the air intake pipe drives the turbine eccentric shaft to rotate, the exhaust pipe exhausts to form an airflow circulation, the rotation of the turbine eccentric shaft drives the connecting rod to shake, the cover plate limits the shaking amplitude of the connecting rod, and the connecting rod drives the shaking body to oscillate synchronously, realizing the rapid fusion of multiple primers. The continuous oscillation allows the primers to be fully mixed, effectively shortening the reaction time. At the same time, the cover plate limits the oscillation to ensure stability, improve experimental efficiency, and meet the experimental requirements of rapid fusion. Attached Figure Description
[0016] Figure 1 This is a perspective view of a rapid preparation device for multiple primers proposed in this utility model; Figure 2 This is an exploded view of the mounting frame mechanism in a rapid preparation device for multiple primers proposed in this utility model; Figure 3 This is a schematic diagram of the monitoring component in a rapid preparation device for multiple primers proposed in this utility model; Figure 4 This is an exploded view of the oscillation mechanism in a rapid preparation device for multiple primers proposed in this utility model; Figure 5 This is a schematic diagram of the housing assembly in a rapid multi-primer preparation device proposed in this utility model; Figure 6 This is an exploded view of the centrifugation mechanism in a rapid preparation device for multiple primers proposed in this utility model; Figure 7 This is an exploded view of the power component in a rapid preparation device for multiple primers proposed in this utility model.
[0017] Legend: 1. Base plate; 2. Outer shell; 3. Mounting frame mechanism; 31. Elevating frame; 32. Placement plate; 33. Lock; 34. Slot; 35. Pressing plate; 36. Pipette; 37. Monitoring assembly; 371. Scale; 372. Observation window; 4. Oscillating mechanism; 41. Housing; 42. Bearing; 43. Turbine eccentric shaft; 44. Inlet pipe; 45. Exhaust pipe; 46. Connecting rod; 47. Cover plate; 48. Shaking body; 5. Centrifuge 51. Air cover; 52. Placement slot; 53. Rotating shaft; 54. Stabilizing pad; 55. Housing assembly; 551. Cover; 552. Control end; 553. Anti-swing pad; 56. Closure assembly; 561. Hinge; 562. Sealing cover; 563. Lock; 57. Power assembly; 571. Motor; 572. Rotating rod; 573. Belt; 574. Conveying rod; 58. Lower cover; 6. Thread; 7. Nut; 8. Primer storage plate. Detailed Implementation
[0018] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model. Reference Figures 1-3 An embodiment of this utility model is provided: a rapid preparation device for multiple primers, including a base plate 1, a shell 2 disposed at the top center of the base plate 1, a mounting frame mechanism 3 disposed on the top left side of the base plate 1, the mounting frame mechanism 3 being used to accelerate the extraction efficiency of multiple primers, an oscillation mechanism 4 disposed inside the shell 2, the oscillation mechanism 4 being used to accelerate the rapid fusion of multiple primers to shorten the reaction time, and a centrifugation mechanism 5 disposed on the top right side of the base plate 1. The mounting frame mechanism 3 includes an overhead frame 31. The bottom of the overhead frame 31 is fixedly connected to the top left side of the base plate 1. A placement plate 32 is slidably connected to the upper middle part of the overhead frame 31. Multiple latches 33 are fixedly connected to the top of the front and rear sides of the overhead frame 31. Two slots 34 are fixedly connected to the front and rear sides of the placement plate 32. A pressing plate 35 is provided on the top of the placement plate 32. Multiple pipettes 36 are installed on the front and rear sides inside the placement plate 32. The tops of the multiple pipettes 36 are fixedly connected to the bottom of the pressing plate 35. A monitoring component 37 is provided on the left side of the outer wall of the multiple pipettes 36. Specifically, the bottom of the elevated frame 31 is fixedly connected to the top left side of the base plate 1, providing a fixed support foundation for the entire mechanism. The placement plate 32 is slidably connected to the upper middle part of the elevated frame 31. By sliding the placement plate 32 along the elevated frame 31, the height position of the placement plate 32 can be adjusted to adapt to different operating scenarios. Through the fixed support of the elevated frame 31 and the sliding cooperation of the placement plate 32, the position of the placement plate 32 can be flexibly adjusted. Multiple latches 33 are fixedly connected to the top of the front and rear sides of the elevated frame 31. Two slots 34 are fixedly connected to the front and rear sides of the placement plate 32. When the placement plate 32 slides to the preset position, the latches 33 and slots 34 engage with each other, restricting the further sliding of the placement plate 32. Through the engagement of the latches 33 and slots 34, the placement plate 32 is stably fixed in the preset position. A pressing plate 35 is provided on the top of the placement plate 32. Multiple pipettes 36 are installed on both the front and rear sides of the interior of the placement plate 32, and the tops of the multiple pipettes 36 are fixedly connected to the bottom of the pressing plate 35. When the pressing plate 35 moves downward, it drives the pipettes 36 to move downward synchronously, completing the aspiration of primers; when the pressing plate 35 returns to its original position, it drives the pipettes 36 to move upward synchronously, completing the dispensing of primers. Through the fixed connection between the pressing plate 35 and the pipettes 36, multiple primer transfer operations are realized. The left side of the outer wall of each of the multiple pipettes 36 is provided with... The monitoring component 37 monitors the pipetting volume and stroke of the pipette 36 in real time and feeds the monitoring information back to the device control system. Through the cooperation of the monitoring component 37 and the pipette 36, the accuracy of the primer transfer process is ensured. With the support of the overhead frame 31, the sliding adjustment of the placement plate 32, the fixing of the latch 33 and the slot 34, the pipetting operation of the pressing plate 35 and the pipette 36, and the monitoring of the monitoring component 37, the mounting frame mechanism 3 realizes the rapid extraction of multiple primers and improves the efficiency and accuracy of multiple primer preparation.
[0019] Reference Figure 4 The oscillation mechanism 4 includes a housing 41, the outer wall of which is located inside the outer shell 2. A bearing 42 is fixedly connected to the rear side of the inner side of the housing 41, and a turbine eccentric shaft 43 is fixedly connected to the front side of the inner side of the bearing 42. An intake pipe 44 is connected to the left side of the bottom of the housing 41, and an exhaust pipe 45 is connected to the right side of the bottom of the housing 41. A connecting rod 46 is fixedly connected to the top of the housing 41, a cover plate 47 is fixedly connected to the top of the outer shell 2, and a swaying body 48 is fixedly connected to the top of the connecting rod 46. Specifically, the outer wall of housing 41 is located inside housing 2. Housing 2 provides mounting and positioning for housing 41, while housing 41 provides enclosed space for the internal components. Through the cooperation between housing 41 and housing 2, the overall stable installation of the oscillation mechanism 4 is achieved. A bearing 42 is fixedly connected to the rear side of the interior of housing 41, and a turbine eccentric shaft 43 is fixedly connected to the front side of the interior of bearing 42. Bearing 42 provides radial support for turbine eccentric shaft 43, reducing frictional resistance during rotation. Through the cooperation between bearing 42 and turbine eccentric shaft 43, the turbine eccentric shaft 43 achieves stable installation. The smooth rotation of the spindle 43 is achieved through an intake pipe 44 connected to the bottom left side of the housing 41. External gas enters the housing 41 through the intake pipe 44, and the airflow acts on the blades of the turbine eccentric shaft 43, driving the turbine eccentric shaft 43 to rotate around the central axis of the bearing 42. An exhaust pipe 45 is connected to the bottom right side of the housing 41, and the gas that drives the turbine eccentric shaft 43 to rotate is discharged from the housing 41 through the exhaust pipe 45, forming an airflow circulation. The combination of intake through the intake pipe 44 and exhaust through the exhaust pipe 45 provides continuous power for the rotation of the turbine eccentric shaft 43. A connecting rod 46 is fixedly connected to the top of the housing 41. The bottom of the connecting rod 46 is connected to the front end of the turbine eccentric shaft 43. When the turbine eccentric shaft 43 rotates, its eccentric structure design causes the connecting rod 46 to periodically sway up and down and left and right. A cover plate 47 is fixedly connected to the top of the housing 2. The cover plate 47 limits the sway range of the connecting rod 46 to prevent excessive swaying. Through the cooperation of the turbine eccentric shaft 43 and the connecting rod 46, the rotational motion of the turbine eccentric shaft 43 is converted into the oscillating motion of the connecting rod 46. A swaying body 48 is fixedly connected to the top of the connecting rod 46. When the connecting rod 46... When oscillation occurs, it causes the shaking body 48 to oscillate synchronously. The primer container placed on the shaking body 48 oscillates along with the shaking body 48, so that the multiple primers in the container are fully mixed. Through the cooperation of the connecting rod 46 and the shaking body 48, the oscillation motion is transmitted to the primer container, realizing the rapid fusion of multiple primers. Through the housing 41 for containment and support, the rotational cooperation of the bearing 42 and the turbine eccentric shaft 43, the airflow drive of the intake pipe 44 and the exhaust pipe 45, the motion transmission of the connecting rod 46 and the shaking body 48, and the limiting of the cover plate 47, the oscillation mechanism 4 realizes the rapid fusion of multiple primers and effectively shortens the reaction time.
[0020] Reference Figures 5-7The centrifuge mechanism 5 includes an air cover 51, the bottom of which is located on the top right side of the base plate 1. A placement groove 52 is engaged with the bottom of the air cover 51. A rotating shaft 53 is located in the lower middle part of the placement groove 52. A stabilizing pad 54 is fixedly connected to the outer wall of the rotating shaft 53. A housing assembly 55 is located on the top right side of the base plate 1. A closing assembly 56 is located on the rear side of the housing assembly 55. A power assembly 57 is located inside the housing assembly 55. A lower cover 58 is fixedly connected to the bottom of the housing assembly 55. The monitoring assembly 37 includes a scale. 371, the right side of the scale 371 is fixedly connected to the upper middle part of the outer wall of the pipette 36, the bottom of the pipette 36 is provided with an observation window 372, the right side of the observation window 372 is installed in the lower middle part of the outer wall of the pipette 36, the housing assembly 55 includes a cover 551, the bottom of the cover 551 is installed on the top right side of the base plate 1, the control end 552 is installed on the front side of the upper middle part of the cover 551, two anti-spinning pads 553 are fixedly connected to the front top of the cover 551, and a stabilizing pad 54 is installed on the bottom inside of the cover 551; Specifically, the right side of the scale 371 is fixedly connected to the upper middle part of the outer wall of the pipette 36, providing a direct reading reference for the pipetting volume; the right side of the observation window 372 is installed on the lower middle part of the outer wall of the pipette 36, allowing direct observation of the liquid state inside the pipette 36. Through the reading of the scale 371 and the visual observation through the observation window 372, accurate monitoring of the pipetting volume and liquid state of the pipette 36 is achieved. The bottom of the gas cap 51 is located on the top right side of the base plate 1, providing top protection for the placement tank 52. The bottom is snapped into the bottom of the gas cap 51 and can rotate with the drive. The inside is used to place a container containing primers. The placement and protection of the primer container is achieved through the cooperation of the gas cap 51 and the placement groove 52. A rotating shaft 53 is provided in the middle and lower part of the placement groove 52. The rotating shaft 53 provides a central axis for the rotation of the placement groove 52. A stabilizing pad 54 is fixedly connected to the outer wall of the rotating shaft 53. The stabilizing pad 54 reduces the radial shaking when the rotating shaft 53 rotates. The stable rotation of the placement groove 52 is achieved through the cooperation of the rotating shaft 53 and the stabilizing pad 54. The casing 551 of the housing assembly 55 is mounted on the top right side of the base plate 1, providing a closed installation space for internal components. A control terminal 552 is installed on the upper front side of the casing 551 for adjusting the operating parameters of the centrifuge mechanism 5. Two anti-splash pads 553 are fixedly connected to the top front side of the casing 551 to prevent accidental liquid spillage during centrifugation. A stabilizing pad 54 is installed on the inner bottom side of the casing 551 to enhance the overall structural stability. Through the cooperation of the casing 551, control terminal 552, anti-splash pads 553, and stabilizing pads 54, the structured installation and operation control of the centrifuge mechanism 5 are achieved. A closing component 56 is provided on the rear side of the housing assembly 55. When the closing component 56 is closed, it forms a closed cavity with the casing 551 to avoid external interference during centrifugation. The internal assembly 55 is equipped with a power assembly 57, which outputs power to drive the rotating shaft 53 to rotate, thereby causing the placement tank 52 and the internal primer container to rotate at high speed, generating centrifugal force to quickly separate or mix the components in the primer solution. Through the cooperation of the closing assembly 56 and the power assembly 57, the centrifugal environment is sealed and the centrifugal power is output. The bottom of the housing assembly 55 is fixedly connected to the bottom of the housing assembly 55. The bottom cover 58 forms a seal and supports the bottom of the housing assembly 55. Through the cooperation of the bottom cover 58 and the housing assembly 55, the overall stability of the centrifugation mechanism 5 is enhanced. The monitoring of the monitoring assembly 37 and the coordinated operation of the centrifugation mechanism 5 realize precise pipetting monitoring and efficient centrifugation in the multiple primer preparation process, and help improve the preparation efficiency and quality.
[0021] Reference Figures 1-7 The closing component 56 includes two hinges 561, the bottom of which is installed on the top rear side of the cover 551. The rear side of the two hinges 561 is fixedly connected to a cover 562, and the top front side of the cover 562 is fixedly connected to a latch 563. The power component 57 includes a motor 571, the rear side of which is fixedly connected to the top front end of the inner side of the cover 551. The output end of the motor 571 is fixedly connected to a rotating rod 572. The bottom of the outer wall of the rotating rod 572 is fixedly connected to a belt 573. The top rear side of the belt 573 is rotatably connected to a conveying rod 574. Multiple threads 6 are installed around the bottom inner wall of the overhead frame 31. Nuts 7 are threadedly connected to the bottom of the multiple threads 6. The top of the shaking body 48 is equipped with a primer storage plate 8. Specifically, the bottoms of both hinges 561 are installed on the top rear side of the cover 551, providing a fulcrum for the cover 562 to rotate. The cover 562 is fixedly connected to the rear side of the two hinges 561. The cover 562 can rotate around the hinges 561 to open and close the top of the cover 551. A latch 563 is fixedly connected to the top front side of the cover 562. When the cover 562 is closed, the latch 563 engages with the corresponding part of the cover 551, restricting the rotation of the cover 562. Through the rotational support of the hinges 561 and the engagement and fixation of the latch 563, the cover 562 controls the closing and opening of the internal space of the centrifugal mechanism 5. The rear side of the motor 571 is fixedly connected to the inner top front side of the cover 551. The motor 571 provides a fixed support for power output. A rotating rod 572 is fixedly connected to the output end of the motor 571. When the motor 571 is running, it drives the rotating rod 572 to rotate synchronously. A belt 573 is fixedly connected to the bottom of the outer wall of the rotating rod 572. When the rotating rod 572 rotates, it drives the belt 573 through friction. A conveying rod 574 is rotatably connected to the top rear side of the belt 573. When the belt 573 is driven, it drives the conveying rod 574 to rotate. The conveying rod 574 is connected to the rotating shaft 53, which in turn drives the rotating shaft 53 and the placement groove 52 to rotate. Through the power output of the motor 571 and the transmission cooperation of the rotating rod 572, belt 573 and conveying rod 574, the rotation drive of the placement groove 52 is realized. Multiple threads 6 are installed around the bottom inner wall of the elevated frame 31. Nuts 7 are threadedly connected to the bottom of the threads 6. The threads 6 pass through the corresponding mounting holes of the base plate 1. After the nuts 7 are tightened, they form a clamping force with the threads 6, fixing the elevated frame 31 to the base plate 1. The threaded engagement of the threads 6 and nuts 7 achieves a stable installation of the elevated frame 31 on the base plate 1. A primer storage plate 8 is installed on the top of the shaking body 48. The primer storage plate 8 is used to place a container containing multiple primers. When the shaking body 48 oscillates, the primer storage plate 8 moves synchronously with the shaking body 48, causing the internal container to oscillate. Through the fixed connection between the shaking body 48 and the primer storage plate 8, the oscillation of the primer container is transmitted, promoting the fusion of multiple primers. The closure component 56 controls the closure, the power component 57 transmits power, the threads 6 and nuts 7 are stably installed, and the primer storage plate 8 acts as a carrier. Together with the auxiliary device, they efficiently complete the preparation of multiple primers.
[0022] Working principle: First, when the device is in its initial state, the base plate 1 provides a stable support foundation for the entire device. The outer shell 2 at the top center of the base plate 1 provides installation space for the oscillation mechanism 4. The mounting frame mechanism 3 on the top left is used to carry out the extraction of multiple primers, and the centrifugation mechanism 5 on the top right is prepared for subsequent centrifugation. The bottom of the elevated frame 31 is fixedly connected to the top left side of the base plate 1, providing fixed support for the entire mechanism. The placement plate 32 is slidably connected to the upper middle part of the elevated frame 31. The operator can adjust its height position by sliding the placement plate 32 to adapt to different operating scenarios. Through the fixed support of the elevated frame 31 and the sliding cooperation of the placement plate 32, the position of the placement plate 32 can be flexibly adjusted. When the placement plate 32 slides to the preset position, multiple latches 33 on the top of the front and rear sides of the elevated frame 31 engage with the two slots 34 on the front and rear sides of the placement plate 32, restricting the further sliding of the placement plate 32. Through the engagement of the latches 33 and the slots 34, the placement plate 32 is stably fixed in the preset position. A pressing plate 35 is provided on the top of the placement plate 32. The tops of multiple pipettes 36 installed on the front and rear sides inside the placement plate 32 are fixedly connected to the bottom of the pressing plate 35. When primers need to be aspirated, the operator moves the pressing plate 35 downward, and the pressing plate 35 drives the pipettes 36 to move downward in sync to complete the aspiration of primers. When primers need to be expelled, the pressing plate 35 returns to its original position upward, and drives the pipettes 36 to move upward in sync to complete the expulsion of primers. Through the fixed connection between the pressing plate 35 and the pipettes 36, the transfer operation of multiple primers can be realized. Each of the multiple pipettes 36 has a monitoring component 37 on the left side of its outer wall. The scale 371 in the monitoring component 37 is fixedly connected to the upper part of the outer wall of the pipette 36 on the right side, providing an intuitive reading reference for the pipetting volume. The observation window 372 is installed on the lower part of the outer wall of the pipette 36 on the right side, allowing direct observation of the liquid state inside the pipette 36. Through the reading of the scale 371 and the visual observation of the observation window 372, accurate monitoring of the pipetting volume and liquid state of the pipette 36 is achieved, and the monitoring information is fed back to the device control system. Through the cooperation of the monitoring component 37 and the pipette 36, the accuracy of the primer transfer process is ensured. With the support of the overhead frame 31, the sliding adjustment of the placement plate 32, the fixing of the latch 33 and the slot 34, the pipetting operation of the pressing plate 35 and the pipette 36, and the monitoring of the monitoring component 37, the mounting frame mechanism 3 realizes the rapid extraction of multiple primers, improving the efficiency and accuracy of multiple primer preparation. After primer extraction is completed, the process of the oscillation mechanism 4 begins. The outer wall of the housing 41 is set inside the outer shell 2. The outer shell 2 provides installation positioning for the housing 41, while the housing 41 provides a closed space for the internal components. Through the cooperation between the housing 41 and the outer shell 2, the overall stable installation of the oscillation mechanism 4 is achieved. The bearing 42, which is fixedly connected to the rear side inside the housing 41, provides radial support for the turbine eccentric shaft 43, which is fixedly connected to the front side inside the housing 41, reducing the frictional resistance when the turbine eccentric shaft 43 rotates. Through the cooperation between the bearing 42 and the turbine eccentric shaft 43, the smooth rotation of the turbine eccentric shaft 43 is achieved. External gas enters the interior of housing 41 through the intake pipe 44 connected to the bottom left of housing 41. The airflow acts on the blades of turbine eccentric shaft 43, driving turbine eccentric shaft 43 to rotate around the central axis of bearing 42. The gas that drives turbine eccentric shaft 43 to rotate is discharged from housing 41 through the exhaust pipe 45 connected to the bottom right of housing 41, forming an airflow cycle. The combination of intake through intake pipe 44 and exhaust through exhaust pipe 45 provides continuous power for the rotation of turbine eccentric shaft 43. The bottom of the connecting rod 46, which is fixedly connected to the top of the housing 41, is connected to the front end of the turbine eccentric shaft 43. When the turbine eccentric shaft 43 rotates, due to its eccentric structure design, it will cause the connecting rod 46 to sway periodically up and down and left and right. The cover plate 47, which is fixedly connected to the top of the housing 2, limits the sway range of the connecting rod 46 to prevent it from swaying too much. Through the cooperation between the turbine eccentric shaft 43 and the connecting rod 46, the rotational motion of the turbine eccentric shaft 43 is converted into the oscillating motion of the connecting rod 46. A shaking body 48 is fixedly connected to the top of the connecting rod 46. A primer storage plate 8 is installed on the top of the shaking body 48. The primer storage plate 8 is used to hold a container containing multiple primers. When the connecting rod 46 oscillates, it will drive the shaking body 48 to oscillate synchronously. The primer storage plate 8 moves synchronously with the shaking body 48, causing the internal container to oscillate, so that the multiple primers in the container are fully mixed. Through the cooperation of the connecting rod 46 and the shaking body 48, the oscillation motion is transmitted to the primer container, realizing the rapid fusion of multiple primers. Through the housing 41 for containment and support, the rotational cooperation of the bearing 42 and the turbine eccentric shaft 43, the airflow drive of the intake pipe 44 and the exhaust pipe 45, the motion transmission of the connecting rod 46 and the shaking body 48, and the limiting of the cover plate 47, the oscillation mechanism 4 realizes the rapid fusion of multiple primers and effectively shortens the reaction time. After oscillation and fusion, the mixture enters the working process of centrifuge mechanism 5. The bottom of the gas cover 51 is located on the top right side of the base plate 1, providing top protection for the placement slot 52. The bottom of the placement slot 52 is snapped into the bottom of the gas cover 51, and its interior is used to place a container containing primers. Through the cooperation between the gas cover 51 and the placement slot 52, the primer container is placed and protected. A rotating shaft 53 is provided in the middle and lower part of the placement slot 52, which provides a central axis for the rotation of the placement slot 52. A stabilizing pad 54 is fixedly connected to the outer wall of the rotating shaft 53. The stabilizing pad 54 reduces the radial shaking when the rotating shaft 53 rotates. Through the cooperation between the rotating shaft 53 and the stabilizing pad 54, the stable rotation of the placement slot 52 is achieved. The bottom of the casing 551 of the housing assembly 55 is installed on the top right side of the base plate 1, providing a closed installation space for the internal components; a control terminal 552 is installed on the upper front side of the casing 551 for adjusting the operating parameters of the centrifuge mechanism 5; two anti-slip pads 553 are fixedly connected to the top front side of the casing 551 to prevent liquid from being accidentally thrown out during centrifugation; a stabilizing pad 54 is installed on the inner bottom side of the casing 551 to enhance the overall structural stability. Through the cooperation of the casing 551, the control terminal 552, the anti-slip pads 553, and the stabilizing pads 54, the structured installation and operation control of the centrifuge mechanism 5 are realized. A closing assembly 56 is provided on the rear side of the housing assembly 55. The bottom of the two hinges 561 of the closing assembly 56 are installed on the top rear side of the cover 551, providing a rotation fulcrum for the cover 562. The cover 562 is fixedly connected to the rear side of the two hinges 561. The cover 562 can rotate around the hinges 561 to open and close the top of the cover 551. A latch 563 is fixedly connected to the top front side of the cover 562. When the cover 562 is closed, the latch 563 engages with the corresponding part of the cover 551 to restrict the rotation of the cover 562. Through the rotational support of the hinges 561 and the engagement and fixation of the latch 563, the cover 562 controls the sealing and opening of the internal space of the centrifuge mechanism 5. When the closing assembly 56 is closed, it forms a closed cavity with the cover 551 to avoid external interference during centrifugation. The housing assembly 55 houses a power assembly 57. The motor 571 of the power assembly 57 is fixedly connected to the rear of the inner top front of the housing 551, providing fixed support for power output. A rotating rod 572 is fixedly connected to the output end of the motor 571, driving the rotating rod 572 to rotate synchronously when the motor 571 operates. A belt 573 is fixedly connected to the bottom of the outer wall of the rotating rod 572, driving the belt 573 through friction when the rotating rod 572 rotates. A conveyor rod 574 is rotatably connected to the rear top of the belt 573. 3. During transmission, the conveyor rod 574 is driven to rotate. The conveyor rod 574 is connected to the rotating shaft 53, which in turn drives the rotating shaft 53 and the placement tank 52 to rotate. Through the power output of the motor 571 and the transmission cooperation of the rotating rod 572, belt 573 and conveyor rod 574, the rotation drive of the placement tank 52 is realized, so that the placement tank 52 and the internal primer container rotate at high speed, generating centrifugal force, which makes the components in the primer solution quickly separate or mix. Through the cooperation of the closing component 56 and the power component 57, the centrifugal environment is sealed and the centrifugal power is output. A lower cover 58 is fixedly connected to the bottom of the housing assembly 55. The lower cover 58 provides a seal and support for the bottom of the housing assembly 55. The cooperation between the lower cover 58 and the housing assembly 55 enhances the overall stability of the centrifugal mechanism 5. Multiple threads 6 are installed around the bottom inner wall of the overhead frame 31. Nuts 7 are threadedly connected to the bottom of the multiple threads 6. The threads 6 pass through the corresponding mounting holes of the base plate 1. After the nuts 7 are tightened, they form a clamping force with the threads 6, fixing the overhead frame 31 to the base plate 1. The threaded cooperation between the threads 6 and the nuts 7 achieves the desired stability. The stable installation of the elevated frame 31 on the base plate 1 ensures the stable operation of the mounting frame mechanism 3. Through the monitoring of the monitoring component 37 and the coordinated operation of the centrifugation mechanism 5, precise pipetting monitoring and efficient centrifugation are achieved in the process of multiple primer preparation, which helps to improve preparation efficiency and quality. Through the coordinated cooperation of the mounting frame mechanism 3, the oscillation mechanism 4, the centrifugation mechanism 5 and other components, this rapid multiple primer preparation device completes the entire process from primer extraction, fusion to centrifugation, realizing rapid and efficient preparation of multiple primers.
[0023] Finally, it should be noted that the above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Although the present utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.
Claims
1. A rapid preparation device for multiple primers, comprising a base plate (1), characterized in that: The top center of the base plate (1) is provided with a shell (2), and the top left side of the base plate (1) is provided with an installation frame mechanism (3). The installation frame mechanism (3) is used to accelerate the extraction efficiency of multiple primers. The shell (2) is provided with an oscillation mechanism (4). The oscillation mechanism (4) is used to accelerate the rapid fusion of multiple primers to shorten the reaction time. The top right side of the base plate (1) is provided with a centrifugation mechanism (5). The mounting frame mechanism (3) includes an overhead frame (31), the bottom of which is fixedly connected to the top left side of the base plate (1). A placement plate (32) is slidably connected to the upper middle part of the overhead frame (31). Multiple latches (33) are fixedly connected to the top of the front and rear sides of the overhead frame (31). Two slots (34) are fixedly connected to the front and rear sides of the placement plate (32). A pressing plate (35) is provided on the top of the placement plate (32). Multiple pipettes (36) are installed on the front and rear sides inside the placement plate (32). The tops of the multiple pipettes (36) are fixedly connected to the bottom of the pressing plate (35). A monitoring component (37) is provided on the left side of the outer wall of the multiple pipettes (36).
2. The rapid preparation device for multiple primers according to claim 1, characterized in that: The oscillation mechanism (4) includes a housing (41), the outer wall of which is located inside the outer shell (2). A bearing (42) is fixedly connected to the rear side of the inner shell (41). A turbine eccentric shaft (43) is fixedly connected to the front side of the inner shell (42). An air intake pipe (44) is connected to the left side of the bottom of the housing (41). An exhaust pipe (45) is connected to the right side of the bottom of the housing (41). A connecting rod (46) is fixedly connected to the top of the housing (41). A cover plate (47) is fixedly connected to the top of the outer shell (2). A swaying body (48) is fixedly connected to the top of the connecting rod (46).
3. The rapid preparation device for multiple primers according to claim 1, characterized in that: The centrifugal mechanism (5) includes an air cover (51), the bottom of which is located on the top right side of the base plate (1). The bottom of the air cover (51) is engaged with a placement groove (52). A rotating shaft (53) is located in the middle and lower part of the placement groove (52). A stabilizing pad (54) is fixedly connected to the outer wall of the rotating shaft (53). A housing assembly (55) is located on the top right side of the base plate (1). A closing assembly (56) is located on the rear side of the housing assembly (55). A power assembly (57) is located inside the housing assembly (55). A lower cover (58) is fixedly connected to the bottom of the housing assembly (55).
4. The rapid preparation device for multiple primers according to claim 1, characterized in that: The monitoring component (37) includes a scale (371), the right side of which is fixedly connected to the upper part of the outer wall of the pipette (36), and an observation window (372) is provided at the bottom of the pipette (36), the right side of which is installed in the lower part of the outer wall of the pipette (36).
5. The rapid preparation device for multiple primers according to claim 3, characterized in that: The housing assembly (55) includes a cover (551), the bottom of which is mounted on the top right side of the base plate (1), a control terminal (552) is mounted on the upper front side of the cover (551), two anti-swing pads (553) are fixedly connected to the top front side of the cover (551), and a stabilizing pad (54) is mounted on the inner bottom side of the cover (551).
6. The rapid preparation device for multiple primers according to claim 3, characterized in that: The closing assembly (56) includes two hinges (561), the bottoms of which are mounted on the top rear side of the cover (551). A cover (562) is fixedly connected to the rear side of the two hinges (561), and a latch (563) is fixedly connected to the top front side of the cover (562).
7. The rapid preparation device for multiple primers according to claim 3, characterized in that: The power assembly (57) includes a motor (571), the rear side of which is fixedly connected to the inner top front end of the cover (551). A rotating rod (572) is fixedly connected to the output end of the motor (571). A belt (573) is fixedly connected to the bottom of the outer wall of the rotating rod (572). A conveying rod (574) is rotatably connected to the rear top of the belt (573).
8. The rapid preparation device for multiple primers according to claim 2, characterized in that: The bottom inner wall of the elevated structure (31) is equipped with multiple threads (6), and the bottom of the multiple threads (6) is threaded with nuts (7). The top of the swaying body (48) is equipped with a primer storage plate (8).