Evaporator for continuously evaporating and concentrating medical liquid medicine

Abstract

The utility model discloses an evaporator for medicine liquid continuous evaporation concentration relates to the medical production technical field, including the original storage tank, the bottom outer wall fixedly connected with the conveying pump of original storage tank, the output of conveying pump is connected with buffer tank through pipeline, buffer tank is connected with evaporating tank through pipeline, evaporating tank is connected with collection jar through pipeline, the utility model provides an evaporator for medicine liquid continuous evaporation concentration, and the liquid enters buffer tank and is scattered by multiple spoiler, reduces the feeding impact and forces to form the disorder turbulence, makes the fluid inside mutual counter -attack, thereby eliminates the periodic pressure pulse of conveying pump, thereby avoids the liquid level of evaporation cavity fluctuation, vacuum degree and heat exchange temperature frequent fluctuation because of pumping pulse, and prevents the concentration deviation of concentrated product, the problem of batch consistency difference, significantly improves the stability and quality control level of medicine liquid concentration.

Description

Technical Field

[0001] This utility model relates to the field of pharmaceutical production technology, specifically to an evaporator for continuous evaporation and concentration of pharmaceutical liquids. Background Technology

[0002] Evaporation and concentration are key processes for purifying, reducing volume, and enriching active ingredients in pharmaceutical solutions. Currently, the evaporation equipment commonly used in the domestic pharmaceutical industry is mainly single-effect intermittent evaporators and small rotary evaporators, whose structures generally consist of a feed pump, evaporation tank, heating jacket, and a simple manual discharge valve. The conventional operation involves batch filling, constant-temperature evaporation, shutdown upon reaching the target, manual discharge, and tank cleaning. A few improved continuous evaporation equipment still use direct feeding methods, lack pressure stabilization and buffering, and have low levels of automation integration.

[0003] To address the issue of unstable feed flow and large fluctuations in evaporation conditions leading to substandard concentrated product quality, existing technologies employ a feed pump to directly pump the liquid into the evaporation chamber. However, this method still suffers from problems such as periodic pulse impacts during fluid transport via the pump, significant fluctuations in the liquid level within the evaporation chamber, frequent fluctuations in the vacuum level and heat exchange temperature, resulting in large deviations in the final concentrated product concentration and poor batch-to-batch consistency. Utility Model Content

[0004] The purpose of this invention is to provide an evaporator for continuous evaporation and concentration of pharmaceutical liquids, in order to solve the problems mentioned in the background art, which are caused by the periodic pulse impact of the pump used to transport the fluid, resulting in significant fluctuations in the liquid level of the evaporation chamber, frequent fluctuations in the vacuum degree and heat exchange temperature in the chamber, and thus large deviations in the concentration of the final concentrated product and poor batch consistency.

[0005] To solve the above-mentioned technical problems, the technical solution adopted by this utility model is as follows: An evaporator for continuous evaporation and concentration of pharmaceutical liquid includes a raw material storage tank. A delivery pump is fixedly connected to the bottom outer wall of the raw material storage tank. The output end of the delivery pump is connected to a buffer tank via a pipe. The buffer tank is connected to an evaporator via a pipe. The evaporator is connected to a collection tank via a pipe. The collection tank is connected to a finished product tank via a pipe. A feeding assembly is provided on the outside of the buffer tank. An evaporation assembly is provided inside the evaporator. A collection assembly is provided inside the collection tank. The feeding assembly includes a baffle plate, the outer wall of which is fixedly connected to the inner wall of the buffer tank. A miniature anti-sedimentation stirring device is fixedly connected to the bottom of the inner wall of the buffer tank, and a flow regulating valve is fixedly connected to the bottom outer wall of the miniature anti-sedimentation stirring device.

[0006] A further improvement of this utility model is that the micro anti-sedimentation stirring device includes a motor, a connecting shaft, a sealing ring, and stirring blades. The motor is installed on the bottom outer wall of the buffer tank. The output end of the motor is fixedly connected to the connecting shaft through a coupling. The outer wall of the connecting shaft away from the motor is fixedly connected to the stirring blades. The inner wall of the buffer tank near the connecting shaft is fixedly connected to the sealing ring, and the sealing ring is made of polytetrafluoroethylene.

[0007] A further improvement of this utility model is that: the evaporation assembly includes a nozzle, the outer wall of which is fixedly connected to the top of the inner wall of the evaporation tank; a liquid level sensor is fixedly connected to the inner wall of the evaporation tank; a circulation pump is fixedly connected to the bottom outer wall of the evaporation tank; the output end of the circulation pump is connected to a heat exchanger via a pipe; the heat exchanger is connected to the circulation nozzle via a pipe; the circulation nozzle is fixedly connected to the inner wall of the evaporation tank; an electronic valve is fixedly connected to the top outer wall of the evaporation tank; a filter is fixedly connected to the outer wall of the electronic valve; and a vacuum pump is connected to the filter via a pipe.

[0008] A further improvement of the present invention is that: the collection assembly includes a condenser recovery unit, the outer wall of which is fixedly connected to the outer wall of the collection tank; a plurality of concentration detectors are fixedly connected to the inner wall of the collection tank; a discharge pump is fixedly connected to the bottom outer wall of the collection tank; the output end of the discharge pump is connected to a buffer tank through a pipe; and a reflux valve is fixedly connected to the top outer wall of the finished product tank, which is connected to the discharge pump through a pipe.

[0009] A further improvement of the present invention is that the flow regulating valve is a two-stage electric pressure regulating valve, comprising a coarse regulating valve and a fine regulating valve arranged in series, both of which are electrically connected to the liquid level sensor.

[0010] A further improvement of this utility model is that: the heat exchanger is a plate heat exchanger or a shell-and-tube heat exchanger, used to recover the waste heat of secondary steam to preheat the circulating liquid; the circulating nozzles are configured as multiple, evenly distributed along the inner wall of the evaporator.

[0011] A further improvement of this utility model is that the vacuum pump is a dry screw vacuum pump or a liquid ring vacuum pump, the air inlet of the vacuum pump is connected to the filter, and the vacuum pump is used to maintain the negative pressure environment inside the evaporator and extract the water vapor generated by evaporation.

[0012] A further improvement of this utility model is that the condenser is a shell-and-tube condenser or a spiral plate condenser, and the cooling medium inlet of the condenser is connected to a chilled water or circulating cooling water pipeline.

[0013] A further improvement of this utility model is that the original storage tank, buffer tank, evaporator, collection tank, and finished product tank are all made of 316L medical-grade stainless steel.

[0014] A further improvement of this utility model is that the baffle, the micro anti-settling stirring device, the flow regulating valve, the nozzle, the circulating nozzle, the filter, the condensate recovery unit, and the connecting pipes between the components are all made of 316L medical stainless steel, and the seals between the connecting pipes are made of polytetrafluoroethylene or EPDM rubber.

[0015] Due to the adoption of the above technical solution, the technological progress achieved by this utility model compared to the prior art is as follows: 1. This utility model provides an evaporator for continuous evaporation and concentration of pharmaceutical liquids. When the liquid enters the buffer tank, it is dispersed by multiple baffles, which reduces the impact of feeding and forces the formation of turbulent flow. This causes the fluid to collide with each other, thereby eliminating the periodic pressure pulses generated by the delivery pump. This avoids frequent fluctuations in liquid level, vacuum degree and heat exchange temperature in the evaporation chamber caused by pumping pulses, thus preventing problems such as large concentration deviation of concentrated products and poor batch consistency, and significantly improving the stability and quality control level of pharmaceutical liquid concentration.

[0016] 2. The evaporator provided by this utility model is equipped with a miniature anti-sedimentation stirring device at the bottom of the buffer tank. The stirring blades are driven by a motor to rotate in the bottom area of ​​the tank, agitating the accumulated impurities and suspending them in the middle of the liquid. This prevents impurities from clogging the outlet and affecting the discharge flow, stabilizes the liquid flow, and prevents the problem of oxidation and decomposition of active ingredients and low product activity retention caused by direct contact between room temperature liquid and high temperature heat exchange wall due to lack of preheating buffer.

[0017] 3. This utility model provides an evaporator for continuous evaporation and concentration of pharmaceutical liquids. A condenser is installed between the collection tank and the evaporation tank to quickly cool water vapor into liquid and discharge it into the collection tank. A concentration detector at the bottom of the collection tank monitors the concentration of the liquid in real time: when the concentration meets the standard, the reflux valve is closed and the discharge pump sends the liquid into the finished product tank; when the concentration does not meet the standard, the reflux valve is opened and the pipeline to the finished product tank is closed, so that the liquid flows back to the buffer tank for re-evaporation and concentration. This structure enables continuous production without stopping the machine, avoiding the production process interruption caused by the need to stop the machine to discharge the liquid and empty the tank after each concentration in traditional concentrators, and significantly improving the continuous operation capability and production efficiency of the device. Attached Figure Description

[0018] Figure 1 This is a schematic diagram of the overall process flow structure of this utility model; Figure 2 This is a partially enlarged structural diagram of the overall process flow of this utility model; Figure 3This is a partially enlarged structural diagram of the overall process flow of this utility model; Figure 4 This is a schematic diagram of the feeding assembly of this utility model; Figure 5 This is a schematic diagram of the evaporation assembly of this utility model; Figure 6 This is a schematic diagram of the collection component of this utility model.

[0019] In the diagram: 1. Raw material storage tank; 2. Buffer tank; 3. Evaporator; 4. Collection tank; 5. Finished product tank; 6. Transfer pump; 7. Feeding assembly; 71. Baffle plate; 72. Miniature anti-sedimentation stirring device; 73. Flow regulating valve; 8. Evaporation assembly; 81. Nozzle; 82. Liquid level sensor; 83. Circulation pump; 84. Heat exchanger; 85. Circulation nozzle; 86. Electronic valve; 87. Filter; 88. Vacuum pump; 9. Collection assembly; 91. Condensation recovery unit; 92. Concentration detector; 93. Discharge pump; 94. Return valve. Detailed Implementation

[0020] The present invention will be further described in detail below with reference to embodiments: Example 1 like Figure 1-4 As shown, this utility model provides an evaporator for continuous evaporation and concentration of pharmaceutical liquids, including a raw material storage tank 1. A transfer pump 6 is fixedly connected to the bottom outer wall of the raw material storage tank 1. The transfer pump 6 controls the discharge speed of the raw material storage tank 1, and the transfer pump 6 is electrically connected to a liquid level sensor 82. The discharge speed of the transfer pump 6 is controlled in real time according to the electrical signal of the liquid level sensor 82. The output end of the transfer pump 6 is connected to a buffer tank 2 through a pipe. The buffer tank 2 is connected to an evaporator 3 through a pipe. The evaporator 3 is connected to a collection tank 4 through a pipe. 4. The liquid is connected to the finished product tank 5 through a pipeline. The liquid first undergoes pressure stabilization and anti-sedimentation treatment in the buffer tank 2, and then enters the evaporator 3 for thin-film evaporation under negative pressure and low temperature conditions. The generated water vapor is liquefied by the condenser 91 and collected in the collection tank 4. The concentration detector 92 at the bottom of the collection tank 4 determines the concentration of the liquid in real time and automatically decides whether to return it to the buffer tank 2 for further concentration or to transport it to the finished product tank 5. The buffer tank 2 is equipped with a feeding component 7 on the outside, the evaporator 3 is equipped with an evaporation component 8 inside, and the collection tank 4 is equipped with a collection component 9 inside. The feeding assembly 7 includes multiple baffles 71, which are evenly distributed circumferentially inside the buffer tank 2 to break up fluid turbulence and eliminate pumping pulses. The outer wall of the baffles 71 is fixedly connected to the inner wall of the buffer tank 2. A miniature anti-settling agitator 72 is fixedly connected to the bottom of the inner wall of the buffer tank 2. A flow regulating valve 73 is fixedly connected to the bottom outer wall of the miniature anti-settling agitator 72. After pressure stabilization and anti-settling treatment, the liquid enters the next process through the flow regulating valve 73. The miniature anti-sedimentation stirring device 72 includes a motor, a connecting shaft, a sealing ring, and stirring blades. The motor is installed on the bottom outer wall of the buffer tank 2. The output end of the motor is fixedly connected to the connecting shaft via a coupling. The outer wall of the connecting shaft away from the motor is fixedly connected to the stirring blades. The stirring blades are driven by the motor to rotate on one side of the bottom of the buffer tank 2. Since both the motor and the stirring blades are located in the bottom area of ​​the buffer tank 2, the rotation of the stirring blades will continuously agitate the liquid inside the buffer tank 2 and agitate the substances that were originally accumulated due to sedimentation, suspending them in the middle part of the liquid. A sealing ring is fixedly connected to the inner wall of the buffer tank 2 near the connecting shaft. The sealing ring is made of polytetrafluoroethylene.

[0021] Example 2 like Figure 2-5 As shown, based on Embodiment 1, this utility model provides a technical solution: Preferably, the evaporation assembly 8 includes a nozzle 81, the outer wall of the nozzle 81 is fixedly connected to the top of the inner wall of the evaporation tank 3, a liquid level sensor 82 is fixedly connected to the inner wall of the evaporation tank 3, the liquid level sensor 82 is set at the bottom of the evaporation tank 3, the liquid level inside the evaporation tank 3 is monitored in real time by the liquid level sensor 82, and the circulation pump 83 is automatically started to send the liquid into the heat exchanger 84 and then back into the evaporation tank 3 for secondary evaporation. The bottom outer wall of the evaporation tank 3 is fixedly connected to the circulation pump 83, the circulation pump 83 draws out the semi-concentrated liquid at the bottom of the evaporation tank 3, sends it into the heat exchanger 84 for compensation heating, and then sprays it back into the tank through the circulation nozzle 85, forming a closed forced circulation evaporation loop, which significantly improves the evaporation efficiency; The output end of the circulating pump 83 is connected to the heat exchanger 84 through a pipe. The heat exchanger 84 is connected to the circulating nozzle 85 through a pipe. The circulating nozzle 85 is fixedly connected to the inner wall of the evaporator 3. The number of circulating nozzles 85 and nozzles 81 is the same, and they are evenly distributed circumferentially on the inner wall of the evaporator 3, so that the liquid forms a thin film that flows along the wall. An electronic valve 86 is fixedly connected to the top outer wall of the evaporator 3. A filter 87 is fixedly connected to the outer wall of the electronic valve 86. The filter 87 filters the water vapor generated inside the evaporator 3 to prevent impurities from flowing out. The filter 87 is connected to a vacuum pump 88 through a pipe. The operation of the vacuum pump 88 extracts the gas inside the evaporator 3 to keep the evaporator 3 in a vacuum state at all times, thereby reducing the boiling temperature of the liquid.

[0022] Example 3 like Figure 3-6 As shown, based on Embodiment 1, this utility model provides a technical solution: Preferably, the collection component 9 includes a condenser 91, the outer wall of the condenser 91 is fixedly connected to the outer wall of the collection tank 4, a plurality of concentration detectors 92 are fixedly connected to the inner wall of the collection tank 4, the concentration detectors 92 are set at the bottom of the inner wall of the collection tank 4, and their probes are inserted into the inside of the collection tank 4 to detect the liquid concentration inside the collection tank 4 in real time, and a discharge pump 93 is fixedly connected to the bottom outer wall of the collection tank 4, the discharge pump 93 is turned on at regular intervals to take out the liquid inside the collection tank 4 and send it into the inside of the finished product tank 5 through the pipeline, or send it back into the inside of the buffer tank 2; The output end of the discharge pump 93 is connected to the buffer tank 2 via a pipe. A reflux valve 94 is fixedly connected to the top outer wall of the finished product tank 5. The reflux valve 94 controls the liquid flow direction inside the connecting pipe between the discharge pump 93 and the buffer tank 2. The concentration detector 92 is electrically connected to the reflux valve 94. The concentration detector 92 controls the opening and closing of the reflux valve 94. When the detected concentration is lower than the preset threshold, the reflux valve 94 opens, and the discharge pump 93 transports the liquid back to the buffer tank 2 for further evaporation and concentration. When the detected concentration reaches or exceeds the preset threshold, the reflux valve 94 closes, and the discharge pump 93 transports the qualified concentrate to the finished product tank 5 for storage. The reflux valve 94 is connected to the discharge pump 93 via a pipe.

[0023] Example 4 like Figure 4-6 As shown, based on Embodiment 1, this utility model provides a technical solution: Preferably, the flow regulating valve 73 is a two-stage electric pressure regulating valve, including a coarse regulating valve and a fine regulating valve arranged in series. Both the coarse regulating valve and the fine regulating valve are electrically connected to the liquid level sensor 82. The flow rate of the liquid can be controlled by the coarse regulating valve and the fine regulating valve arranged in series, so as to avoid the situation where the concentration efficiency of the device is reduced due to sudden fluctuations in flow rate. The heat exchanger 84 is a plate heat exchanger or a shell-and-tube heat exchanger, which is used to recover the waste heat of secondary steam to preheat the circulating liquid. Multiple circulating nozzles 85 are arranged and evenly distributed along the inner wall of the evaporator 3. The vacuum pump 88 is a dry screw vacuum pump or a liquid ring vacuum pump. The air inlet of the vacuum pump 88 is connected to the filter 87. The vacuum pump 88 is used to maintain the negative pressure environment inside the evaporator 3 and extract the water vapor generated by evaporation. The condenser recovery unit 91 is a shell-and-tube condenser or a spiral plate condenser. The cooling medium inlet of the condenser recovery unit 91 is connected to a chilled water or circulating cooling water pipeline.

[0024] Example 5 like Figure 1-6As shown, based on Embodiment 1, this utility model provides a technical solution: Preferably, the original storage tank 1, buffer tank 2, evaporator 3, collection tank 4, and finished product tank 5 are all made of 316L medical-grade stainless steel. This material has excellent corrosion resistance to chloride ions, acid, alkali, and salt solutions, and is suitable for common acidic, alkaline, and high-salt environments in pharmaceutical solutions. It also has the advantages of not releasing harmful substances, not reacting with the components of the drug solution, and ensuring the purity and safety of the drug. The inner wall of the tank is polished to meet the requirements of pharmaceutical-grade smoothness, and the surface is dense and smooth, making it difficult for materials to adhere. It supports CIP online cleaning and SIP online steam sterilization. The baffle 71, the micro anti-sedimentation stirring device 72, the flow regulating valve 73, the nozzle 81, the circulating nozzle 85, the filter 87, the condenser recovery unit 91, and the connecting pipes between the components are all made of 316L medical-grade stainless steel. The seals between the connecting pipes are made of polytetrafluoroethylene or EPDM rubber.

[0025] The working principle of this evaporator used for continuous evaporation and concentration of pharmaceutical liquids will be explained in detail below.

[0026] like Figure 1-6 As shown, the liquid material inside the original storage tank 1 is drawn out by the delivery pump 6 and discharged directly into the buffer tank 2 through the pipeline. Since multiple baffles 71 are evenly distributed around the inside of the buffer tank 2, the liquid material is dispersed by the baffles 71 as soon as it enters the buffer tank 2. In this way, the impact generated when the liquid material enters the buffer tank 2 is reduced, and the liquid material is forced to form a turbulent flow, so that the fluids inside the tank collide with each other, eliminating the periodic pressure impact generated when the delivery pump 6 delivers the liquid. At the bottom of the buffer tank 2, a miniature anti-sedimentation stirring device 72 is installed. The stirring blades are driven by the motor inside the miniature anti-sedimentation stirring device 72 to rotate in the bottom area of ​​the buffer tank 2. The rotation of the stirring blades agitates the impurities that have accumulated at the bottom of the buffer tank 2 and suspends them in the middle of the liquid material, so as to prevent the liquid outlet from being blocked by the accumulation of impurities and affecting the discharge flow rate, thus stabilizing the liquid flow.

[0027] Two flow regulating valves 73 are arranged in series between the connecting pipes of buffer tank 2 and evaporator 3. The two flow regulating valves 73 are a coarse adjustment valve and a fine adjustment valve, respectively. By controlling the opening and closing of these two valves, the flow rate of liquid discharged from buffer tank 2 into evaporator 3 can be precisely controlled.

[0028] Subsequently, the liquid is sprayed out through multiple nozzles 81 installed inside the evaporator 3. Since the multiple nozzles 81 are evenly distributed circumferentially against the inner wall of the evaporator 3, the sprayed liquid will form a thin film that flows against the inner wall of the evaporator 3. The inner wall of the evaporator 3 is equipped with heating elements, so this method can improve the efficiency of heat transfer by the heating elements and accelerate the evaporation rate of the liquid. The unevaporated liquid will accumulate inside the evaporator 3. The liquid level sensor 82 detects the liquid level inside the evaporator 3. If it exceeds the danger level, the circulation pump 83 installed at the bottom of the evaporator 3 will be automatically activated to suck out the semi-concentrated liquid accumulated inside the evaporator 3. The liquid is then reheated by the heat exchanger 84. The reheated liquid will be sprayed into the evaporator 3 through the circulation nozzles 85. The number and arrangement of the circulation nozzles 85 correspond to the nozzles 81 and can achieve the same effect.

[0029] Simultaneously, during the evaporation of the liquid in the evaporator 3, the vacuum pump 88 connected to the outside of the evaporator 3 will start synchronously to draw out the gas inside the evaporator 3, ensuring that the evaporator 3 will always maintain a negative pressure vacuum state during use, thereby lowering the boiling point of the liquid and accelerating the evaporation efficiency. At the same time, the generated water vapor will also be drawn out of the evaporator 3 by the vacuum pump 88 and filtered by the filter 87 set on the outside of the evaporator 3 to prevent impurities from being mixed in and discharged into the collection tank 4.

[0030] Furthermore, a condenser 91 is installed in the connecting pipe between the collection tank 4 and the evaporator 3. The condenser 91 rapidly cools the water vapor into liquid and discharges it into the collection tank 4. The concentration of the liquid inside the collection tank 4 is detected by the concentration detector 92 installed at the bottom of the collection tank 4. When the concentration of the liquid reaches the standard, the concentration detector 92 will control the reflux valve 94 to close. At this time, the liquid is drawn out by the timed discharge pump 93 and flows into the finished product tank 5. If the concentration of the liquid does not meet the standard, the concentration detector 92 will control the reflux valve 94 to open and close the pipe leading to the finished product tank 5. At this time, the liquid sucked out by the discharge pump 93 will flow back into the buffer tank 2 through the pipe, and after being evaporated and concentrated again, it will be sent into the finished product tank 5. In this way, the concentration of the liquid inside the finished product tank 5 can be ensured to be stable.

[0031] The present invention has been described in detail above. However, modifications or improvements can be made to it, which will be obvious to those skilled in the art. Therefore, any modifications or improvements that do not depart from the spirit of the present invention are within the protection scope of the present invention.

Claims

1. An evaporator for continuous evaporation and concentration of pharmaceutical liquid, comprising a raw material storage tank (1), wherein a transfer pump (6) is fixedly connected to the bottom outer wall of the raw material storage tank (1), the output end of the transfer pump (6) is connected to a buffer tank (2) via a pipe, the buffer tank (2) is connected to an evaporator (3) via a pipe, the evaporator (3) is connected to a collection tank (4) via a pipe, and the collection tank (4) is connected to a finished product tank (5) via a pipe, characterized in that: The buffer tank (2) is provided with a feeding assembly (7) on its outside, the evaporator (3) is provided with an evaporation assembly (8) inside, and the collection tank (4) is provided with a collection assembly (9) inside. The feeding assembly (7) includes a baffle (71), the outer wall of which is fixedly connected to the inner wall of the buffer tank (2), a micro anti-settling stirring device (72) is fixedly connected to the bottom of the inner wall of the buffer tank (2), and a flow regulating valve (73) is fixedly connected to the bottom outer wall of the micro anti-settling stirring device (72).

2. The evaporator for continuous evaporation and concentration of pharmaceutical liquids according to claim 1, characterized in that: The micro anti-sedimentation stirring device (72) includes a motor, a connecting shaft, a sealing ring and stirring blades. The motor is installed on the bottom outer wall of the buffer tank (2). The output end of the motor is fixedly connected to the connecting shaft through a coupling. The outer wall of the connecting shaft away from the motor is fixedly connected to the stirring blades. The inner wall of the buffer tank (2) near the connecting shaft is fixedly connected to the sealing ring. The sealing ring is made of polytetrafluoroethylene.

3. The evaporator for continuous evaporation and concentration of pharmaceutical liquids according to claim 1, characterized in that: The evaporation assembly (8) includes a nozzle (81), the outer wall of which is fixedly connected to the top of the inner wall of the evaporator (3). A liquid level sensor (82) is fixedly connected to the inner wall of the evaporator (3). A circulation pump (83) is fixedly connected to the bottom outer wall of the evaporator (3). The output end of the circulation pump (83) is connected to a heat exchanger (84) through a pipe. The heat exchanger (84) is connected to a circulation nozzle (85) through a pipe. The circulation nozzle (85) is fixedly connected to the inner wall of the evaporator (3). An electronic valve (86) is fixedly connected to the top outer wall of the evaporator (3). A filter (87) is fixedly connected to the outer wall of the electronic valve (86). A vacuum pump (88) is connected to the filter (87) through a pipe.

4. An evaporator for continuous evaporation and concentration of pharmaceutical liquids according to claim 1, characterized in that: The collection assembly (9) includes a condenser (91), the outer wall of which is fixedly connected to the outer wall of the collection tank (4), a number of concentration detectors (92) are fixedly connected to the inner wall of the collection tank (4), a discharge pump (93) is fixedly connected to the bottom outer wall of the collection tank (4), the output end of the discharge pump (93) is connected to the buffer tank (2) through a pipe, and a reflux valve (94) is fixedly connected to the top outer wall of the finished product tank (5), the reflux valve (94) is connected to the discharge pump (93) through a pipe.

5. An evaporator for continuous evaporation and concentration of pharmaceutical liquids according to claim 1, characterized in that: The flow regulating valve (73) is a two-stage electric pressure regulating valve, including a coarse adjustment valve and a fine adjustment valve arranged in series. Both the coarse adjustment valve and the fine adjustment valve are electrically connected to the liquid level sensor (82).

6. An evaporator for continuous evaporation and concentration of pharmaceutical liquids according to claim 3, characterized in that: The heat exchanger (84) is a plate heat exchanger or a shell-and-tube heat exchanger, used to recover the waste heat of secondary steam to preheat the circulating liquid. The circulating nozzles (85) are arranged in multiples and are evenly distributed along the inner wall of the evaporator (3).

7. An evaporator for continuous evaporation and concentration of pharmaceutical liquids according to claim 3, characterized in that: The vacuum pump (88) is a dry screw vacuum pump or a liquid ring vacuum pump. The air inlet of the vacuum pump (88) is connected to the filter (87). The vacuum pump (88) is used to maintain the negative pressure environment inside the evaporator (3) and extract the water vapor generated by evaporation.

8. An evaporator for continuous evaporation and concentration of pharmaceutical liquids according to claim 4, characterized in that: The condenser recovery unit (91) is a shell-and-tube condenser or a spiral plate condenser, and the cooling medium inlet of the condenser recovery unit (91) is connected to a chilled water or circulating cooling water pipeline.

9. An evaporator for continuous evaporation and concentration of pharmaceutical liquids according to claim 1, characterized in that: The original storage tank (1), buffer tank (2), evaporator (3), collection tank (4), and finished product tank (5) are all made of 316L medical stainless steel.

10. An evaporator for continuous evaporation and concentration of pharmaceutical liquids according to claim 1, characterized in that: The baffle (71), the micro anti-settling stirring device (72), the flow regulating valve (73), the nozzle (81), the circulating nozzle (85), the filter (87), the condenser recovery unit (91), and the connecting pipes between the components are all made of 316L medical stainless steel, and the seals between the connecting pipes are made of polytetrafluoroethylene or EPDM rubber.

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