Ultrasonic cell pulverizer for reagent kit production

Abstract

The utility model discloses a reagent kit production is with ultrasonic cell grinder relates to ultrasonic cell grinder field, the utility model discloses a crusher main part and ultrasonic generator are personally experienced sth, and the inside of crusher main part is equipped with the lift platform, and the outer surface of lift platform is equipped with recess, and the inside of recess installs the motor on the upper installation, and the output of motor is connected with the lead screw. The utility model discloses through being provided with rack, gear, worm, worm wheel, pivot, side plate, slide, sliding slot and clamping plate, when needing to carry out the clamping to the glass beaker of sample solution, the staff can rotate worm through knob, and worm drives worm wheel to rotate, then drives pivot to rotate, then drives gear to rotate, and gear drives two racks to move to each other, and rack drives slide and side plate to move again, and drives clamping plate to move, when clamping plate and glass beaker are pasted and do not rotate worm again, can, at this moment, two clamping plates can carry out the clamping limit position to glass beaker.

Description

Technical Field

[0001] This utility model relates to the field of ultrasonic cell disruptors, specifically an ultrasonic cell disruptor for reagent kit production. Background Technology

[0002] Ultrasonic cell disruptors are used in the production of reagent kits. In the processing of biotinylated antibody diluents, the dispersion effect of ultrasound in liquids is utilized to create cavitation, thereby breaking down solid particles in the liquid. Ultrasonic cell disruptors are of great significance in reagent kit production and are widely used in various operations such as cell disruption, emulsification, separation, dispersion, homogenization, extraction, and degassing. They are ideal devices for accelerating chemical, biological, and physical reaction rates and for accelerating liquid degassing.

[0003] Chinese Patent No. CN218609759U discloses an ultrasonic cell disruptor for reagent kit production. This invention improves the stability of the ultrasonic cell disruptor's installation position, increases disruption efficiency, and extends the lifespan of its components by adjusting the levelness of the ultrasonic disruptor body using four adjustable supports in an adjustable base structure. The adjustment operation is simple and convenient, and it has wide applicability.

[0004] Regarding the aforementioned patent content, a placement platform is provided to hold a glass beaker containing a sample solution, allowing the beaker to move upwards to ensure that the end of the amplitude transformer can be immersed in the solution for cell disruption. However, when disrupting the cells in the solution, both the glass beaker and the amplitude transformer must be in the center position, thus preventing the beaker from shifting. However, simply placing the glass beaker on the placement platform and keeping it stationary with the weight of the solution without any restraint may cause it to shift due to vibration during operation, thereby affecting the effect of the amplitude transformer on disrupting the cells in the solution. Utility Model Content

[0005] Based on this, the purpose of this utility model is to provide an ultrasonic cell disruptor for reagent kit production, so as to solve the technical problem that the beaker may shift during the disruption of solution cells, thus affecting the disruption effect.

[0006] To achieve the above objectives, this utility model provides the following technical solution: an ultrasonic cell disruptor for reagent kit production, comprising a disruptor body and an ultrasonic generator. The disruptor body has a lifting platform inside, and a groove is formed on the outer surface of the lifting platform. A motor is installed inside the groove, and a lead screw is connected to the output end of the motor. A movable seat is fitted onto the outer wall of the lead screw. A bottom shell is installed on the outer surface of the movable seat, and a placement platform is bolted to the top of the bottom shell. Slide grooves are formed on both sides of the top of the placement platform, and a sliding plate is installed inside the slide grooves. A side plate is installed on the top of the sliding plate, and a clamping plate is detachably installed on one side of the side plate. A rack is installed at the bottom of the sliding plate. A rotating shaft is connected to the middle of the bottom shell via a bearing, and a worm gear and a gear are respectively installed on the outer wall of the rotating shaft. A worm is also connected to the inside of the bottom shell via a bearing.

[0007] By adopting the above technical solution, when the worm drives the worm wheel to rotate, the worm wheel can drive the shaft to rotate, which in turn drives the gear to rotate, and then drives the two racks to move.

[0008] Furthermore, a slot is provided on one side of the side plate, and an insert plate is inserted into the slot, with one side of the insert plate being fixedly connected to the clamping plate.

[0009] By adopting the above technical solution, when installing the clamp, the clamp can be inserted into the slot to position the clamp.

[0010] Furthermore, the top of the insert plate is threaded with a locking bolt extending into the side plate, and the insert plate is adapted to the slot.

[0011] By adopting the above technical solution, when the locking bolt is screwed into the side plate, the insert plate can be locked and limited to prevent it from moving out of the slot.

[0012] Furthermore, both the clamping plate and the side plate are slidably connected to the slide groove via a sliding plate, and the clamping plate is made of PTFE material.

[0013] By adopting the above technical solution, when the skateboard slides inside the groove, it will drive the side plate to move, and then drive the clamping plate to move, so as to adjust the position of the clamping plate.

[0014] Furthermore, one end of the worm extends to the outside of the bottom shell and is equipped with a knob, and the worm meshes with a worm wheel.

[0015] By adopting the above technical solution, it is convenient for staff to rotate the worm gear by turning the knob, and the rotation of the worm gear will drive the worm wheel to rotate.

[0016] Furthermore, an ultrasonic transducer is installed on the top of the crusher body, and an amplitude transformer is installed at the bottom of the ultrasonic transducer. The ultrasonic transducer and the ultrasonic generator are connected by a cable.

[0017] By adopting the above technical solution, during operation, the ultrasonic generator converts the input electrical energy into a high-frequency AC signal, while the ultrasonic transducer converts the high-frequency electrical signal provided by the ultrasonic generator into high-frequency mechanical vibration, which is then transmitted to the sample solution through the amplitude transformer.

[0018] Furthermore, the inner wall of the crusher body is provided with a sound insulation layer.

[0019] By adopting the above technical solutions, the sound insulation layer can improve the sound insulation effect of the crusher body.

[0020] Furthermore, a cabinet door is installed on the outer surface of the crusher body via hinges, a sealing ring is installed on the cabinet door, and a viewing window is installed on the outer surface of the cabinet door.

[0021] By adopting the above technical solution, the viewing window facilitates observation of the internal condition of the crusher body.

[0022] Furthermore, the movable seat is threadedly connected to the lead screw, and both sides of the movable seat are in contact with the inner wall of the groove. A limit rod is also installed inside the groove, and the limit rod passes through the movable seat.

[0023] By adopting the above technical solution, when the lead screw rotates, it will drive the movable seat to move, and the limit rod can guide and limit the movable seat, so that the movable seat can move smoothly.

[0024] Furthermore, the worm gear is located directly below the gear, and the two racks are staggered, with both racks meshing with the gear.

[0025] By adopting the above technical solution, when the gear rotates, it will drive the two racks to move, and the racks will drive the slide to move.

[0026] In summary, the present invention has the following main advantages:

[0027] 1. This utility model, by incorporating a rack, gear, worm, worm wheel, rotating shaft, side plate, sliding plate, chute, and clamping plate, allows the operator to clamp a glass beaker containing a sample solution. The operator can rotate the worm by turning a knob, which in turn rotates the worm wheel, which in turn rotates the rotating shaft, which in turn rotates the gear. The gear then moves the two racks in opposite directions, which in turn move the sliding plate and side plate, and finally the clamping plate. Once the clamping plate is in contact with the glass beaker, the worm can be stopped. At this point, the two clamping plates can clamp and limit the glass beaker. Simultaneously, the simultaneous movement of the two clamping plates ensures the glass beaker is in the center position and prevents it from shifting during the operation of the crusher, thus improving the cell crushing effect and enhancing the stability of the glass beaker.

[0028] 2. This utility model is equipped with a worm and a worm wheel. Because the worm and worm wheel have self-locking properties, when the worm is not rotated, the worm wheel will not rotate, thereby preventing the gear from rotating. This improves the stability of the rack and the clamping plate and prevents the clamping plate and rack from moving randomly.

[0029] 3. This utility model is equipped with a slot, a locking bolt, and a slot. When the clamp needs to be replaced, the operator can rotate the locking bolt to unscrew it from the side plate, and then move the insert plate out of the slot. At this time, the clamp can be removed for replacement. Attached Figure Description

[0030] Figure 1 This is a schematic diagram of the overall three-dimensional structure of this utility model;

[0031] Figure 2 This is a schematic diagram of the main structure of the crusher of this utility model;

[0032] Figure 3 This is a schematic diagram of the cross-sectional structure of the main body of the crusher of this utility model;

[0033] Figure 4 This is a schematic diagram of the lifting platform structure of this utility model;

[0034] Figure 5 This is a schematic diagram of the movable seat structure of this utility model;

[0035] Figure 6 This is a schematic diagram of the placement platform structure of this utility model;

[0036] Figure 7 This is a schematic diagram of the cross-sectional structure of the bottom shell of this utility model;

[0037] Figure 8 This is a schematic diagram of the bottom shell structure of this utility model;

[0038] Figure 9 This is a schematic diagram of the clamping plate structure of this utility model.

[0039] In the diagram: 1. Crusher body; 2. Ultrasonic generator; 3. Control panel; 4. Ultrasonic transducer; 5. Amplitude bar; 6. Cabinet door; 7. Sealing ring; 8. Viewing window; 9. Lifting platform; 10. Groove; 11. Motor; 12. Lead screw; 13. Movable seat; 14. Placement platform; 15. Slide; 16. Side plate; 17. Slide plate; 18. Rack; 19. Bottom shell; 20. Gear; 21. Shaft; 22. Worm gear; 23. Worm; 24. Slot; 25. Insert plate; 26. Locking bolt; 27. Clamping plate; 28. Sound insulation layer; 29. ​​Limiting rod. Detailed Implementation

[0040] The technical solutions of the present invention will be clearly and completely described below with reference to the accompanying drawings. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain the present invention, and should not be construed as limiting the present invention.

[0041] The embodiments of this utility model will be described below based on its overall structure.

[0042] Example 1:

[0043] An ultrasonic cell disruptor for reagent kit production, such as Figures 1-9 As shown, the device includes a crusher body 1 and an ultrasonic generator 2. An ultrasonic transducer 4 is installed on the top of the crusher body 1, and an amplitude transformer 5 is installed at the bottom of the ultrasonic transducer 4. The ultrasonic transducer 4 and the ultrasonic generator 2 are connected by a cable. During operation, the ultrasonic generator 2 converts the input electrical energy into a high-frequency AC signal, while the ultrasonic transducer 4 converts the high-frequency electrical signal provided by the ultrasonic generator 2 into high-frequency mechanical vibration, which is transmitted to the sample solution through the amplitude transformer 5. The crusher body 1 has a lifting platform 9 inside, and the outer surface of the lifting platform 9 has a groove 10. A motor 11 is installed inside the groove 10, and the output end of the motor 11 is... A lead screw 12 is connected, and a movable seat 13 is fitted on the outer wall of the lead screw 12. A bottom shell 19 is installed on the outer surface of the movable seat 13, and a placement platform 14 is installed on the top of the bottom shell 19 by bolts. Slide grooves 15 are opened on both sides of the top of the placement platform 14, and a sliding plate 17 is set inside the slide grooves 15. A cabinet door 6 is installed on the outer surface of the crusher body 1 by hinges. A sealing ring 7 is installed on the cabinet door 6. A viewing window 8 is installed on the outer surface of the cabinet door 6. The viewing window 8 is set to facilitate observation of the internal situation of the crusher body 1. A control panel 3 is installed on the outer surface of the ultrasonic generator 2. The control panel 3 is electrically connected to the ultrasonic generator 2, the ultrasonic transducer 4, and the motor 11 respectively.

[0044] See Figures 2-8The skateboard 17 has a side plate 16 installed on its top, and a clamping plate 27 is detachably installed on one side of the side plate 16. A rack 18 is installed on the bottom of the skateboard 17. A rotating shaft 21 is connected to the center of the bottom shell 19 via a bearing. A worm gear 22 and a gear 20 are respectively installed on the outer wall of the rotating shaft 21. Both the gear 20 and the rack 18 are made of plastic-coated steel, with stainless steel as the base material and POM composite material as the outer layer. A worm 23 is also connected to the inside of the bottom shell 19 via a bearing. When the worm 23 drives the worm gear 22 to rotate, the worm gear 22 drives the rotating shaft 21 to rotate, which in turn drives the gear 20 to rotate, and moves the two racks 18. The clamping plate 27 is in a [position missing]. The clamping plate 27 and the side plate 16 are both slidably connected to the slide groove 15 via the sliding plate 17. The clamping plate 27 is made of PTFE material and has a fluororubber pad on the inner side. The inner wall of the fluororubber pad has an anti-slip texture. When the sliding plate 17 slides inside the slide groove 15, it will drive the side plate 16 to move, and then drive the clamping plate 27 to move, so as to adjust the position of the clamping plate 27. One end of the worm 23 extends to the outside of the bottom shell 19 and is equipped with a knob. The worm 23 meshes with the worm wheel 22, which makes it easy for the operator to rotate the worm 23 by the knob. After the worm 23 rotates, it will drive the worm wheel 22 to rotate. The bottom of the clamping plate 27 and the side plate 16 are both in contact with the top of the placement platform 14.

[0045] See Figures 2-7 The movable seat 13 is threadedly connected to the lead screw 12. The bottom end of the lead screw 12 is connected to the lower part of the groove 10 through a bearing. Both sides of the movable seat 13 are in contact with the inner wall of the groove 10. A limit rod 29 is also installed inside the groove 10. The limit rod 29 passes through the movable seat 13. When the lead screw 12 rotates, it will drive the movable seat 13 to move. The limit rod 29 can guide and limit the movable seat 13, so that the movable seat 13 can move smoothly. The worm gear 22 is located directly below the gear 20. The two racks 18 are staggered and both racks 18 mesh with the gear 20. When the gear 20 rotates, it will drive the two racks 18 to move. The racks 18 will drive the slide plate 17 to move. The lead screw 12 is made of stainless steel, and the worm gear 22 and worm 23 are both made of copper alloy.

[0046] Example 2:

[0047] Based on the above embodiment 1, the following structure will be set up so that the clamping plate 27 can be replaced.

[0048] Specifically, a slot 24 is provided on one side of the side plate 16, and a plate 25 is inserted into the slot 24. One side of the plate 25 is fixedly connected to the clamp 27. When installing the clamp 27, the clamp 27 can be inserted into the slot 24 to position the clamp 27. The top of the plate 25 is threaded with a locking bolt 26 extending into the side plate 16. The plate 25 is adapted to the slot 24. The side plate 16 has a screw hole so that the locking bolt 26 can be screwed in. When the locking bolt 26 is screwed into the side plate 16, the plate 25 can be locked and limited to prevent the plate 25 from moving out of the slot 24.

[0049] Example 3:

[0050] Based on the above embodiment 1, in order to improve the sound insulation effect of the crusher body 1, the following structure will be set.

[0051] See Figures 2-3 The inner wall of the crusher body 1 is provided with a sound insulation layer 28, which is made of polyester fiber material. The sound insulation layer 28 can improve the sound insulation effect of the crusher body 1.

[0052] The working principle of this utility model is as follows: First, when using it, turn on the power, then open the cabinet door 6, and place the glass beaker containing the sample solution at the top center of the placement platform 14. Then, the operator can rotate the worm gear 23 through the knob. The worm gear 23 drives the worm wheel 22 to rotate, which in turn drives the rotating shaft 21 to rotate, which in turn drives the gear 20 to rotate. The gear 20 drives the two racks 18 to move towards each other. The racks 18 then drive the slide plate 17 and the side plate 16 to move, and drive the clamping plate 27 to move. When the clamping plate 27 is in contact with the glass beaker, the worm gear 23 can be stopped. At this time, the two clamping plates 27 can clamp and limit the glass beaker. At the same time, since the two clamping plates 27 move at the same time, it can ensure that the glass beaker is in the center position.

[0053] Next, the motor 11 is started. The operation of the motor 11 drives the lead screw 12 to rotate. The rotation of the lead screw 12 causes the movable seat 13 to move upward, which in turn causes the placement platform 14 to move upward, and the glass beaker to move upward. When the end of the amplitude rod 5 is inserted below the sample liquid surface, the motor 11 is turned off, and then the cabinet door 6 is closed. Then the ultrasonic generator 2 is started. The ultrasonic generator 2 converts the input electrical energy into a high-frequency AC signal, and the ultrasonic transducer 4 converts the high-frequency electrical signal provided by the ultrasonic generator 2 into high-frequency mechanical vibration, which is transmitted to the sample solution through the amplitude rod 5 to break the cells. The sound insulation layer 28 can play a role in noise reduction. The setting of the viewing window 8 makes it easy for the staff to observe the situation inside the crusher body 1. And because the clamping plate 27 clamps and limits the glass beaker, it prevents the beaker from shifting when the crusher body 1 is working, which would affect the cell breaking effect.

[0054] When the clamp 27 needs to be replaced, the operator can rotate the locking bolt 26 to unscrew the locking bolt 26 from the side plate 16, and then move the insert plate 25 out of the slot 24. At this time, the clamp 27 can be removed for replacement.

[0055] Although embodiments of the present invention have been shown and described, these specific embodiments are merely explanations of the present invention and are not intended to limit the invention. The specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples. After reading this specification, those skilled in the art may make modifications, substitutions, and variations to the embodiments as needed without departing from the principles and spirit of the present invention, provided that such modifications, substitutions, and variations are within the scope of the claims of the present invention and are protected by patent law.

Claims

1. An ultrasonic cell disruptor for reagent kit production, comprising a disruptor body (1) and an ultrasonic generator (2), characterized in that: The crusher body (1) is equipped with a lifting platform (9) inside, and a groove (10) is provided on the outer surface of the lifting platform (9). A motor (11) is installed inside the groove (10) and the output end of the motor (11) is connected to a lead screw (12). A movable seat (13) is fitted on the outer wall of the lead screw (12). A bottom shell (19) is installed on the outer surface of the movable seat (13), and a placement platform (14) is installed on the top of the bottom shell (19) by bolts. Both sides of the top of the placement platform (14) are provided with... There is a slide groove (15), and a slide plate (17) is provided inside the slide groove (15). A side plate (16) is installed on the top of the slide plate (17), and a clamping plate (27) is detached on one side of the side plate (16). A rack (18) is installed on the bottom of the slide plate (17). A rotating shaft (21) is connected to the middle position of the bottom shell (19) through a bearing. A worm gear (22) and a gear (20) are respectively installed on the outer wall of the rotating shaft (21). A worm (23) is also connected to the inside of the bottom shell (19) through a bearing.

2. The ultrasonic cell disruptor for reagent kit production according to claim 1, characterized in that: A slot (24) is provided on one side of the side plate (16), and a plug plate (25) is inserted inside the slot (24). One side of the plug plate (25) is fixedly connected to the clamp plate (27).

3. The ultrasonic cell disruptor for reagent kit production according to claim 2, characterized in that: The top of the insert (25) is threaded with a locking bolt (26) extending into the side plate (16), and the insert (25) is adapted to the slot (24).

4. The ultrasonic cell disruptor for reagent kit production according to claim 1, characterized in that: The clamping plate (27) and the side plate (16) are slidably connected to the slide groove (15) via the sliding plate (17), and the clamping plate (27) is made of PTFE material.

5. The ultrasonic cell disruptor for reagent kit production according to claim 1, characterized in that: One end of the worm (23) extends to the outside of the bottom shell (19) and is fitted with a knob. The worm (23) meshes with the worm wheel (22).

6. The ultrasonic cell disruptor for reagent kit production according to claim 1, characterized in that: An ultrasonic transducer (4) is installed on the top of the main body (1) of the crusher, and an amplitude transformer (5) is installed at the bottom of the ultrasonic transducer (4). The ultrasonic transducer (4) and the ultrasonic generator (2) are connected by a cable.

7. The ultrasonic cell disruptor for reagent kit production according to claim 1, characterized in that: The inner wall of the crusher body (1) is provided with a sound insulation layer (28).

8. The ultrasonic cell disruptor for reagent kit production according to claim 1, characterized in that: The outer surface of the crusher body (1) is fitted with a cabinet door (6) via a hinge. A sealing ring (7) is installed on the cabinet door (6), and a viewing window (8) is installed on the outer surface of the cabinet door (6).

9. The ultrasonic cell disruptor for reagent kit production according to claim 1, characterized in that: The movable seat (13) is threadedly connected to the lead screw (12). Both sides of the movable seat (13) are in contact with the inner wall of the groove (10). A limit rod (29) is also installed inside the groove (10), and the limit rod (29) passes through the movable seat (13).

10. The ultrasonic cell disruptor for reagent kit production according to claim 1, characterized in that: The worm gear (22) is located directly below the gear (20), and the two racks (18) are staggered and both racks (18) mesh with the gear (20).

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