A micro-tissue DNA extraction oscillation lysis device

Abstract

The utility model relates to microtissue DNA extraction oscillation lysis device technical field, especially microtissue DNA extraction oscillation lysis device, including bottom plate and riser, the top left and right sides of bottom plate are respectively with two riser bottom fixedly connected, the top of riser is fixedly connected with the top plate, the top of top plate is connected with the pad protection structure, the top front and back sides of top plate are connected with control structure respectively, the new multiple pad plate are inserted with the first bender and second bender inner wall slot respectively, then multiple straight boards are down turned through the curved plate inner wall pin shaft, make multiple straight boards bottom respectively with the top of first bender and second bender adhere, multiple bolts are down turned and are connected with the top round mouth of first bender and second bender threaded connection through multiple straight boards, complete the replacement of pad plate, realize pad plate split type connection, reduced the pad replacement difficulty of oscillation lysis device, prevent the maintenance cost increase of oscillation lysis device.

Description

Technical Field

[0001] This utility model relates to the technical field of micro-tissue DNA extraction and oscillation device, specifically a micro-tissue DNA extraction and oscillation device. Background Technology

[0002] The main function of the micro-tissue DNA extraction oscillating lysis device is to assist cell lysis through mechanical vibration, thereby accelerating protein digestion and DNA release.

[0003] For example, a DNA extraction EP tube oscillator with authorization announcement number "CN222007750U" expands laterally due to the limitation of the top and bottom plates. This allows the expansion of the air bladder to reduce the size of the installation opening, thereby squeezing and fixing the EP tube placed in the installation hole, ensuring the stability of the EP tube during placement and preventing loosening or detachment. The overall structure is simple to operate and easy to use, effectively improving the fixing efficiency of the EP tube. However, in the use of the oscillation lysis device, although the rubber pad in the installation hole can enhance friction, the rubber material is prone to aging after long-term use, which may affect the fixing effect. In addition, the rubber pad is fixedly connected to the air bladder, and the air bladder is prone to tearing and leakage during replacement, requiring repair or replacement of the air bladder. This increases the difficulty of replacing the pad of the oscillation lysis device, leading to an increase in the maintenance cost of the oscillation lysis device. Utility Model Content

[0004] The purpose of this invention is to solve the problem that the increased difficulty in replacing the pads of the oscillating lysis device leads to increased maintenance costs, and a micro-tissue DNA extraction oscillating lysis device is proposed.

[0005] To achieve the above objectives, this utility model provides the following technical solution:

[0006] A micro-tissue DNA extraction and oscillation device is designed, comprising a base plate and vertical plates. The top left and right sides of the base plate are fixedly connected to the bottom of two vertical plates respectively. A top plate is fixedly connected to the top of the vertical plates. A padding structure is connected to the top of the top plate. Control structures are connected to the front and rear sides of the top of the top plate respectively.

[0007] This feature includes an opening machined into the outer wall of the top plate, the interior of which can be used to prevent test tubes from entering.

[0008] Preferably, the padding structure includes a first bent plate and a second bent plate. The bottoms of the two first bent plates are fixedly connected to the front and rear sides of the top of the top plate, respectively. The outer wall of the first bent plate is adjacent to the outer wall of the second bent plate. The bottom of the second bent plate is in contact with the top of the top plate. Pads are inserted into the grooves of the inner walls of the first and second bent plates, respectively. Curved plates are fixedly connected to the top left side of the first and second bent plates, respectively. A straight plate is rotatably connected to the inner wall of the curved plate.

[0009] This design allows the pad to be inserted into the slots of the first and second curved plates, thus realizing a separate pad design and facilitating pad replacement.

[0010] Preferably, protruding plates are fixedly connected to the front and rear ends of the inner sides of the two vertical plates, and the top of the protruding plates is fixedly connected to the bottom of the top plate.

[0011] This feature allows the convex plates to support the vertical plates on both sides and the top plate, preventing deformation of the vertical plates and the top plate.

[0012] Preferably, a vibration motor is fixed to the outer wall of the convex plate.

[0013] Preferably, the control structure includes upright plates and screws, the bottoms of the two upright plates are respectively fixed to the front and rear sides of the top of the top plate, the inner wall of the upright plates is threaded to the outer wall of the screw, and a handle is fixed to the end of the screw.

[0014] In this configuration, the screw rotates back and forth along the inner wall of the vertical plate, causing the second curved plate to move back and forth, thus cooperating with the first curved plate to clamp the test tube.

[0015] Preferably, the outer wall of the screw is threaded with a collar.

[0016] In this configuration, the collar rotates back and forth along the outer wall of the screw, causing the outer wall of the collar to abut against the outer wall of the upright plate, thus fixing the screw.

[0017] Preferably, the inner side of the outer wall of the screw is rotatably connected to the outer wall of the second curved plate.

[0018] The present invention provides a micro-tissue DNA extraction and oscillating lysis device with the following advantages: After the pad is damaged, multiple bolts in the pad structure rotate upwards via multiple straight plates, disengaging the bottom of the bolts from the top circular openings of the first and second curved plates. Then, the left side of the straight plate rotates upwards via the pin shaft on the inner wall of the curved plate, disengaging the straight plates from the tops of the first and second curved plates. Subsequently, multiple pads are pushed upwards, repositioning them into the first and second curved plates. New pads are then inserted into the grooves on the inner walls of the first and second curved plates. The straight plates then rotate downwards via the pin shaft on the inner wall of the curved plate, bringing their bottoms into contact with the tops of the first and second curved plates. Multiple bolts rotate downwards via the straight plates and threadedly connect to the top circular openings of the first and second curved plates, completing the pad replacement. This achieves a separate pad connection, reducing the difficulty of replacing the pads in the oscillating lysis device and preventing increased maintenance costs. Attached Figure Description

[0019] Figure 1 This is a schematic diagram of the structure of this utility model;

[0020] Figure 2 for Figure 1 A schematic diagram of the connection structure of the first curved plate in the middle;

[0021] Figure 3 for Figure 1 A schematic diagram showing the connection relationship between the first curved plate, the pad plate, and the curved plate.

[0022] Figure 4 for Figure 1 A schematic diagram of the structure of A in the middle;

[0023] Figure 5 for Figure 1 A schematic diagram showing the connection relationship between the bottom plate, vertical plate, and convex plate.

[0024] In the diagram: 1. Base plate, 2. Pad structure, 201. First curved plate, 202. Second curved plate, 203. Pad plate, 204. Curved plate, 205. Straight plate, 3. Control structure, 301. Vertical plate, 302. Screw, 303. Handle, 304. Collar, 4. Vertical plate, 5. Top plate, 6. Protruding plate, 7. Vibration motor. Detailed Implementation

[0025] The present invention will be further described below with reference to the accompanying drawings:

[0026] Please see Figure 1-5In this embodiment, a micro-tissue DNA extraction and oscillation device includes a base plate 1 and a vertical plate 4. The top left and right sides of the base plate 1 are fixedly connected to the bottom of the two vertical plates 4 respectively. A top plate 5 is fixedly connected to the top of the vertical plates 4. A test tube can be inserted into the opening processed on the outer wall of the top plate 5. A padding structure 2 is connected to the top of the top plate 5. A control structure 3 is connected to the front and rear sides of the top of the top plate 5 respectively.

[0027] The padding structure 2 includes a first bent plate 201 and a second bent plate 202. The bottoms of the two first bent plates 201 are fixedly connected to the front and rear sides of the top of the top plate 5, respectively. The outer wall of the first bent plate 201 is adjacent to the outer wall of the second bent plate 202. The bottom of the second bent plate 202 is in contact with the top of the top plate 5. The inner wall grooves of the first bent plate 201 and the second bent plate 202 are respectively inserted with pads 203, which are rubber plates. The top left sides of the first bent plate 201 and the second bent plate 202 are respectively fixedly connected with curved plates 204. The inner wall of the curved plate 204 is rotatably connected with a straight plate 205. The left side of the outer wall of the straight plate 205 is rotated through the pin on the inner wall of the curved plate 204 under force.

[0028] After the pad 203 is damaged in the pad structure 2, multiple bolts are rotated upwards through multiple straight plates 205, causing the bottom of the outer wall of the multiple bolts to disengage from the top circular opening of the first bent plate 201 and the second bent plate 202. Then, the left side of the outer wall of the straight plate 205 is rotated upwards through the pin shaft of the inner wall of the curved plate 204, causing the multiple straight plates 205 to disengage from the top of the first bent plate 201 and the second bent plate 202. Subsequently, multiple pads 203 are pushed upwards, causing the multiple pads 203 to respectively disengage from the first bent plate 201 and the second bent plate 202. Finally, new multiple pads 203 are installed. The first and second curved plates 201 and 202 are inserted into the grooves on their inner walls. Then, multiple straight plates 205 are rotated downwards through the pin shafts on the inner wall of the curved plate 204, so that the bottoms of the multiple straight plates 205 are respectively attached to the tops of the first and second curved plates 201 and 202. Multiple bolts are connected to the top round threads of the first and second curved plates 201 and 202 through the downward rotation of the multiple straight plates 205, thus completing the replacement of the pad 203. This achieves a split connection of the pad 203, reduces the difficulty of replacing the pad of the oscillating pyrolysis device, and prevents an increase in the maintenance cost of the oscillating pyrolysis device.

[0029] Two vertical plates 4 are fixedly connected to the front and rear ends of their inner sides, respectively. The top of the protruding plate 6 is fixedly connected to the bottom of the top plate 5. A vibration motor 7 is fixedly connected to the outer wall of the protruding plate 6. The vibration motor 7 is palm-sized and of model DIN-J14. The control structure 3 includes a vertical plate 301 and a screw 302. The bottom of the two vertical plates 301 is fixedly connected to the front and rear sides of the top of the top plate 5, respectively. The inner wall of the vertical plate 301 is threadedly connected to the outer wall of the screw 302. The screw 302 rotates back and forth through the inner wall of the vertical plate 301 under force. A handle 303 is fixedly connected to the end of the screw 302. The handle 303 facilitates the rotation of the screw 302. A collar 304 is threadedly connected to the outer wall of the screw 302. The collar 304 rotates back and forth through the outer wall of the screw 302 under force. The inner side of the outer wall of the screw 302 is rotatably connected to the outer wall of the second bent plate 202. The inner side of the outer wall of the screw 302 rotates with the bearing in the outer wall of the second bent plate 202.

[0030] Working principle:

[0031] Micro-tissue DNA extraction and lysis apparatus test tube setup:

[0032] Insert the test tube containing a trace amount of tissue DNA into the opening on the outer wall of the top plate 5. At the same time, the outer wall of the test tube is in contact with the outer wall of the pad 203 on the inner wall of the first curved plate 201. Then, grasp the handle 303 and rotate the screw 302 inward through the upright plate 301. The rotating screw 302 moves the second curved plate 202 inward, so that the pad 203 on the inner wall of the second curved plate 202 is pressed against the other side of the outer wall of the test tube. Then, the collar 304 is rotated inward through the outer wall of the screw 302, so that the outer wall of the collar 304 is pressed against the outer wall of the upright plate 301, thus completing the fixation of the test tube.

[0033] Micro-tissue DNA extraction and lysis device operation:

[0034] When the vibration motor 7 (which can adjust its own vibration frequency) is powered on, it generates a slight vibration. The vibration is transmitted to the vertical plate 4 through the convex plate 6, and then to the top plate 5 through the vertical plate 4. Finally, it is transmitted to the test tube held by the top plate 5 and the padding structure 2. At this time, the vibration will accelerate the lysis of trace tissue DNA in the test tube. Then the vibration motor 7 stops working, and the collar 304 is rotated outward by the screw 302, so that the collar 304 is separated from the outer wall of the vertical plate 301. Then, the test tube is held above, and the screw 302 is rotated outward by the handle 303 on the outer wall of the vertical plate 301. The rotating screw 302 moves the second curved plate 202 outward and separates it from the test tube. Then, the test tube is pulled upward by hand to separate it from the opening on the outer wall of the top plate 5.

[0035] Replacement of the pad for the micro-tissue DNA extraction and lysis device:

[0036] After the pad 203 is damaged, multiple bolts are rotated upward through multiple straight plates 205, causing the bottom of the outer wall of the multiple bolts to disengage from the top round opening of the first bent plate 201 and the second bent plate 202. Then, the left side of the outer wall of the straight plate 205 is rotated upward through the inner wall pin of the curved plate 204, causing the multiple straight plates 205 to disengage from the top of the first bent plate 201 and the second bent plate 202. Subsequently, multiple pads 203 are pushed upward, causing the multiple pads 203 to be inserted into the first bent plate 201 and the second bent plate 202 respectively. Then, new multiple pads 203 are inserted into the grooves on the inner wall of the first bent plate 201 and the second bent plate 202 respectively. Then, multiple straight plates 205 are rotated downward through the inner wall pin of the curved plate 204, causing the bottom of the multiple straight plates 205 to be in contact with the top of the first bent plate 201 and the second bent plate 202 respectively. Multiple bolts are rotated downward through multiple straight plates 205 and threadedly connected to the top round opening of the first bent plate 201 and the second bent plate 202, completing the replacement of the pad 203.

[0037] Although the present invention has been illustrated and described with reference to preferred embodiments, those skilled in the art should understand that various changes in form and detail are possible within the scope of the claims.

Claims

1. A micro-tissue DNA extraction and lysis device, comprising a base plate (1) and a vertical plate (4), characterized in that: The top left and right sides of the bottom plate (1) are fixedly connected to the bottom of the two vertical plates (4), the top of the vertical plate (4) is fixedly connected to the top plate (5), the top of the top plate (5) is connected to the padding structure (2), and the front and rear sides of the top of the top plate (5) are respectively connected to the control structure (3).

2. The micro-tissue DNA extraction and lysis apparatus according to claim 1, characterized in that: The padding structure (2) includes a first bent plate (201) and a second bent plate (202). The bottoms of the two first bent plates (201) are fixed to the front and rear sides of the top of the top plate (5), respectively. The outer wall of the first bent plate (201) is adjacent to the outer wall of the second bent plate (202). The bottom of the second bent plate (202) is in contact with the top of the top plate (5). The inner wall grooves of the first bent plate (201) and the second bent plate (202) are respectively inserted with pads (203). The top left side of the first bent plate (201) and the second bent plate (202) are respectively fixed with curved plates (204). The inner wall of the curved plate (204) is rotatably connected with a straight plate (205).

3. The micro-tissue DNA extraction and lysis apparatus according to claim 1, characterized in that: The two vertical plates (4) are respectively fixed to the front and rear ends of the inner side with protruding plates (6), and the top of the protruding plates (6) is fixed to the bottom of the top plate (5).

4. The micro-tissue DNA extraction and oscillation device according to claim 3, characterized in that: A vibration motor (7) is fixed to the outer wall of the protruding plate (6).

5. The micro-tissue DNA extraction and lysis apparatus according to claim 1, characterized in that: The control structure (3) includes a vertical plate (301) and a screw (302). The bottoms of the two vertical plates (301) are respectively fixed to the front and rear sides of the top of the top plate (5). The inner wall of the vertical plate (301) is threaded to the outer wall of the screw (302). The end of the screw (302) is fixed with a handle (303).

6. The micro-tissue DNA extraction and lysis apparatus according to claim 5, characterized in that: The outer wall of the screw (302) is threaded with a collar (304).

7. The micro-tissue DNA extraction and lysis apparatus according to claim 5, characterized in that: The inner side of the outer wall of the screw (302) is rotatably connected to the outer wall of the second bending plate (202).

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