A new centrifugal enrichment device for making cell wax blocks

Abstract

The utility model relates to medical technology field in general, and more particularly to a novel centrifugal enrichment device of cell wax block making, include: centrifugal tube, embedding paper, draw a line and support piece, embedding paper is set in centrifugal tube in near bottom position, draw a line one end is connected with embedding paper, and the other end extends to the pipe orifice position of centrifugal tube, the support piece sets up in centrifugal tube bottom, and supports embedding paper, the application is through embedding paper setting in centrifugal tube bottom, and when centrifugal enrichment, cell will be attached on embedding paper, when transferring cell wax block making, embedding paper is taken out directly through draw a line, the cell adhesion in centrifugal tube bottom or lateral wall is reduced, and when transferring cell block, can better keep the integrity of cell block, reduce the cell injury because of operation, effectively solve the problem that cell block structure is vulnerable to damage and cell loss rate is high in traditional craft.

Description

Technical Field

[0001] This utility model generally relates to the field of medical technology, and more specifically, to a novel centrifugal enrichment device for preparing cell wax blocks. Background Technology

[0002] Cell paraffin blocks are one of the key techniques in cytopathology for processing liquid specimens, allowing liquid samples to be preserved for a long time, facilitating further pathological molecular biological analysis and subsequent examinations.

[0003] Currently, traditional cell block fabrication processes have some limitations. For example, before fabricating cell blocks, centrifugation is required. During centrifugation, cells tend to accumulate at the bottom of the centrifuge tube. The cell block structure is easily damaged during the transfer process, and because cells may remain at the bottom or sidewall of the centrifuge tube, the cell loss rate is relatively high. Utility Model Content

[0004] This application provides a novel centrifugal enrichment device for preparing cell wax blocks to solve the above-mentioned technical problems.

[0005] This application provides a novel centrifugal enrichment device for preparing cell wax blocks, comprising: a centrifuge tube, embedding paper, a lifting thread, and a support member. The embedding paper is disposed inside the centrifuge tube near the bottom. One end of the lifting thread is connected to the embedding paper, and the other end extends to the opening of the centrifuge tube. The support member is disposed at the bottom of the centrifuge tube and supports the embedding paper.

[0006] According to some embodiments of the present invention, the shape of the embedding paper matches the cross-sectional shape of the centrifuge tube.

[0007] According to some embodiments of the present invention, the lifting lines include four sets, which are respectively connected to the 0°, 90°, 180° and 270° positions of the embedding paper.

[0008] According to some embodiments of the present invention, the support member includes a partition and a frame, wherein a plurality of partitions are arranged in the frame and are interconnected with each other.

[0009] According to some embodiments of the present invention, the top of the support member is a plane, and the bottom of the support member matches the bottom shape of the centrifuge tube.

[0010] As can be seen from the above technical solution, the advantages and positive effects of this novel centrifugal enrichment device for preparing cell blocks are as follows: By placing the embedding paper at the bottom of the centrifuge tube, cells adhere to the embedding paper during centrifugation. When transferring the cell blocks, the embedding paper is directly removed by a lifting thread, reducing cell adhesion to the bottom or sidewall of the centrifuge tube. Simultaneously, the integrity of the cell blocks is better maintained during transfer, reducing cell damage caused by operation. This effectively solves the problems of easily damaged cell block structure and high cell loss rate in traditional processes. The support not only provides stable support for the embedding paper but also ensures its fixed position during centrifugation, thereby improving the centrifugal enrichment effect. Attached Figure Description

[0011] To more clearly illustrate the technical solutions in the embodiments of this application or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this application. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0012] Figure 1 This is a schematic diagram of the structure of a novel centrifugal enrichment device for preparing cell wax blocks disclosed in an embodiment of this application;

[0013] Figure 2 This is a top view schematic diagram of the embedding paper of a novel centrifugal enrichment device for preparing cell wax blocks disclosed in the embodiments of this application;

[0014] Figure 3 This is a top view schematic diagram of the support component of a novel centrifugal enrichment device for preparing cell wax blocks, as disclosed in an embodiment of this application.

[0015] Explanation of reference numerals in the attached figures:

[0016] 1. Centrifuge tubes; 2. Embedding paper; 3. Lifting thread; 4. Support components; 5. Partitions; 6. Frame. Detailed Implementation

[0017] The embodiments of this application will be further described in detail below with reference to the accompanying drawings and examples. The detailed description of the following embodiments and the accompanying drawings are used to illustrate the principles of this application by way of example, but should not be used to limit the scope of this application. This application can be implemented in many different forms and is not limited to the specific embodiments disclosed herein, but includes all technical solutions falling within the scope of the claims.

[0018] These embodiments are provided to make the application thorough and complete, and to fully express the scope of the application to those skilled in the art. It should be noted that, unless otherwise specifically stated, the relative arrangement of components and steps, material composition, numerical expressions, and values ​​illustrated in these embodiments should be interpreted as merely exemplary and not as limiting.

[0019] It should be noted that, in the description of this application, unless otherwise stated, "a plurality of" means two or more; the terms "upper," "lower," "left," "right," "inner," and "outer," etc., indicating orientation or positional relationship, are only for the convenience of describing this application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this application. When the absolute position of the described object changes, the relative positional relationship may also change accordingly.

[0020] Furthermore, the terms "first," "second," and similar terms used in this application do not indicate any order, quantity, or importance, but are merely used to distinguish different parts. "Vertical" is not strictly vertical, but within the permissible margin of error. "Parallel" is not strictly parallel, but within the permissible margin of error. Terms such as "including" or "contains" mean that the element preceding the word encompasses the element listed after it, and do not exclude the possibility of encompassing other elements as well.

[0021] It should also be noted that, in the description of this application, unless otherwise expressly specified and limited, the terms "installation," "connection," and "joining" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a direct connection or an indirect connection through an intermediate medium. Those skilled in the art can understand the specific meaning of the above terms in this application depending on the specific circumstances. When a specific device is described as being located between a first device and a second device, an intermediary device may or may not be present between the specific device and the first or second device.

[0022] All terms used in this application have the same meaning as understood by one of ordinary skill in the art to which this application pertains, unless otherwise specifically defined. It should also be understood that terms defined in general dictionaries should be interpreted as having meanings consistent with their meanings in the context of the relevant art, and not as idealized or highly formalized, unless expressly defined herein.

[0023] Techniques, methods, and equipment known to those skilled in the art may not be discussed in detail, but where appropriate, they should be considered part of the specification.

[0024] like Figure 1 As shown in the embodiment, a novel centrifugal enrichment device for preparing cell blocks includes: a centrifuge tube 1, embedding paper 2, a lifting thread 3, and a support 4. The embedding paper 2 is disposed inside the centrifuge tube 1 near the bottom. One end of the lifting thread 3 is connected to the embedding paper 2, and the other end extends to the opening of the centrifuge tube 1. The support 4 is disposed at the bottom of the centrifuge tube 1 and supports the embedding paper 2. By placing the embedding paper 2 at the bottom of the centrifuge tube 1, cells adhere to the embedding paper 2 during centrifugation. When transferring the cell blocks, the embedding paper 2 is directly removed via the lifting thread 3, reducing cell adhesion to the bottom or sidewalls of the centrifuge tube 1. Simultaneously, the integrity of the cell blocks is better maintained during transfer, reducing cell damage caused by operation. This effectively solves the problems of easily damaged cell block structure and high cell loss rate in traditional processes. The support 4 not only provides stable support for the embedding paper 2 but also ensures its fixed position during centrifugation, thereby improving the centrifugation enrichment effect.

[0025] like Figure 2 As shown, in some embodiments of this invention, the shape of the embedding paper 2 matches the cross-sectional shape of the centrifuge tube 1. This matching design ensures that the embedding paper 2 completely covers the bottom area of ​​the centrifuge tube 1, preventing cells from slipping to the edges or sidewalls during centrifugation, thereby improving the uniformity and integrity of cell enrichment. Especially for trace samples, this greatly reduces cell loss during the operation.

[0026] like Figure 2 As shown, in some embodiments of this invention, the lifting threads 3 comprise four sets, respectively connected to the 0°, 90°, 180°, and 270° positions of the embedding paper 2. This symmetrical distribution facilitates the rapid and stable removal of the embedding paper 2 via the lifting threads 3 after centrifugation, reducing cell loss during the operation and ensuring the high efficiency of subsequent cell block preparation.

[0027] like Figure 3 As shown, in some embodiments of this utility model, the support member 4 includes partitions 5 and a frame 6, with multiple partitions 5 intersecting and connecting to each other within the frame 6. The partitions 5 intersect to form a grid structure, which can stably support the embedding paper 2, keeping it flat during centrifugation and preventing wrinkles or displacement due to centrifugal force, thereby ensuring that cells are evenly distributed on the surface of the embedding paper 2.

[0028] like Figure 3As shown, in some embodiments of this utility model, the top of the support member 4 is a flat surface, and the bottom of the support member 4 matches the bottom shape of the centrifuge tube 1. This design allows the support member 4 to be stably placed inside the centrifuge tube 1. The top flat surface provides a flat and reliable support base for the embedding paper 2, ensuring that the embedding paper 2 can fully contact the support surface during centrifugation. At the same time, the close fit between the bottom and the bottom of the centrifuge tube 1 effectively prevents the support member 4 from shifting or shaking inside the tube during centrifugation, ensuring the stable transmission of centrifugal force.

[0029] The embodiments of this application have now been described in detail. To avoid obscuring the concept of this application, some details known in the art have not been described. Those skilled in the art can fully understand how to implement the technical solutions disclosed herein based on the above description.

[0030] While specific embodiments of this application have been described in detail by way of examples, those skilled in the art should understand that the above examples are for illustrative purposes only and are not intended to limit the scope of this application. Those skilled in the art should understand that modifications can be made to the above embodiments or equivalent substitutions can be made to some technical features without departing from the scope and spirit of this application. In particular, as long as there is no structural conflict, the various technical features mentioned in the embodiments can be combined in any manner.

Claims

1. A novel centrifugal enrichment device for making cell wax blocks, characterized in that, include: The centrifuge tube (1), embedding paper (2), lifting thread (3), and support member (4) are provided. The embedding paper (2) is located inside the centrifuge tube (1) near the bottom. One end of the lifting thread (3) is connected to the embedding paper (2), and the other end extends to the opening of the centrifuge tube (1). The support member (4) is located at the bottom of the centrifuge tube (1) and supports the embedding paper (2).

2. The novel centrifugal enrichment device for making cell wax blocks according to claim 1, characterized in that: The shape of the embedding paper (2) matches the cross-sectional shape of the centrifuge tube (1).

3. The novel centrifugal enrichment device for making cell wax blocks according to claim 1, characterized in that: The lifting wire (3) comprises four sets, which are respectively connected to the 0°, 90°, 180° and 270° positions of the embedding paper (2).

4. The novel centrifugal enrichment device for preparing cell wax blocks according to claim 1, characterized in that: The support member (4) includes a partition (5) and a frame (6), wherein a plurality of partitions (5) are arranged in the frame (6) and are interconnected with each other.

5. The novel centrifugal enrichment device for making cell wax blocks according to claim 4, characterized in that: The top of the support member (4) is flat, and the bottom of the support member (4) matches the bottom shape of the centrifuge tube (1).

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