A liquid path system of a wafer pushing machine

Abstract

The utility model discloses a kind of liquid path systems of pusher, it includes sampling unit, sample adding unit and cleaning unit.Sample adding unit in sampling unit is connected with sample adding unit in sampling pipeline, and sampling pipeline is equipped with the valve body of controlling its on-off on sampling unit and sample adding unit;Common pipeline is communicated at sampling pipeline and sample adding pipeline intercommunication, and another end of common pipeline is communicated on the working interface of plunger pump;The first cleaning pipeline end of cleaning unit is communicated sampling pipeline, and another end is communicated diluent tank, power pump is equipped on the first cleaning pipeline, second cleaning pipeline one end is communicated first cleaning pipeline, and another end is communicated another working interface on the plunger pump;Second cleaning pipeline and first cleaning pipeline are all equipped with the valve body of controlling its on-off.The utility model realizes accurate sample adding, and sample reagent processing period is short to sample, significantly improve the work efficiency of pusher.

Description

Technical Field

[0001] This utility model relates to the field of automated testing technology for medical devices, and in particular to a liquid circuit system for a pusher. Background Technology

[0002] In medical testing, slide pushers are used to support blood smears for microscopic examination. This process requires the precise and automated application of minute amounts of blood sample onto a glass slide.

[0003] Existing liquid circuit systems for tablet pushers typically involve sequential steps of installation, sampling, sample addition, and tubing cleaning, resulting in low overall efficiency. Therefore, there is an urgent need for a liquid circuit system that can achieve accurate sample addition and a short sample processing cycle. Utility Model Content

[0004] To solve the above-mentioned technical problems, this utility model provides a liquid circuit system for a tablet pusher, which can achieve precise sample addition and has a short sample reagent processing cycle, significantly improving the working efficiency of the tablet pusher.

[0005] The technical solution of this utility model is:

[0006] A fluid circuit system for a wafer pusher, characterized in that it comprises:

[0007] The sampling unit includes a puncture needle and a sampling tubing connected to the puncture needle. The output end of the sampling tubing is connected to a common tubing. The sampling tubing is provided with V1 valve and V2 valve at intervals to control its on / off state. The other end of the common tubing is connected to a working port on a plunger pump.

[0008] The sampling unit includes a sampling needle and a sampling tubing connected to the sampling needle. The input end of the sampling tubing is connected to the output end of the common tubing and the sampling tubing. The sampling tubing is equipped with a V3 valve to control its on / off state.

[0009] The cleaning unit includes a first cleaning pipeline, one end of which is connected to the sampling pipeline and located between valves V1 and V2, and the other end of which is connected to the diluent tank. The first cleaning pipeline is equipped with a P1 power pump for providing power to transport the diluent, and a V4 valve for controlling its on / off state. The second cleaning pipeline has one end connected to the first cleaning pipeline and located between valve V4 and the P1 power pump, and the other end connected to another working port on the plunger pump. The second cleaning pipeline is equipped with a V5 valve for controlling its on / off state.

[0010] Furthermore, the cleaning unit also includes two cleaning tanks, which are respectively positioned below the puncture needle or the sample application needle;

[0011] One of the cleaning tanks is connected to a first waste liquid pipeline, and the other cleaning tank is connected to a second waste liquid pipeline. The other ends of the first and second waste liquid pipelines extend toward each other and are connected to a V6 valve. The V6 valve is connected to a third waste liquid pipeline.

[0012] The third waste liquid pipeline is connected to the waste liquid tank. A P2 power pump for providing power to transport waste liquid in the cleaning tank is provided on the third waste liquid pipeline and between the V6 valve and the waste liquid tank. The V6 valve can switch and selectively connect one of the cleaning tanks to the third waste liquid pipeline.

[0013] Furthermore, the sampling pipeline includes a first sampling pipeline and a second sampling pipeline;

[0014] One end of the first sampling line is connected to the puncture needle, and the other end is connected to one end of the second sampling line. The V1 valve is located on the first sampling line, and the V2 valve is located on the second sampling line. One end of the first cleaning line is connected to the junction of the first sampling line and the second sampling line.

[0015] One end of the sample addition pipeline is connected to the other end of the second sampling pipeline, and one end of the common pipeline is connected to the junction of the sample addition pipeline and the second sampling pipeline.

[0016] Furthermore, valves V1, V2, and V3 are all pinch valves.

[0017] Furthermore, the V4 valve and V5 valve are two-way diaphragm valves, and the V6 valve is a two-position three-way diaphragm valve.

[0018] Furthermore, the P1 power pump is a peristaltic pump.

[0019] Furthermore, the P2 power pump is a diaphragm pump.

[0020] The beneficial technical effects of this utility model are:

[0021] I. This invention utilizes a plunger pump as the core driving force, combined with a clamp valve control, to achieve precise sampling and dispensing of sample reagents. Furthermore, unlike the sequential sampling, dispensing, and cleaning processes in existing technologies, the sampling unit, dispensing unit, and cleaning unit of this invention work in coordination. The cleaning process of the sampling unit can be initiated simultaneously with the dispensing of sample reagents onto the slide, achieving a simultaneous dispensing and cleaning mode. This significantly shortens the processing cycle for a single sample reagent and improves the efficiency of the slide pusher. Additionally, after sample dispensing, this invention sequentially cleans the dispensing tubing and common tubing in sections, ensuring thorough cleaning of all parts of the liquid path while optimizing cleaning efficiency.

[0022] Second, this utility model utilizes a plunger pump for sampling and adding power, a peristaltic pump for delivering large-flow cleaning fluid, and a diaphragm pump for extracting waste liquid, thus ensuring the sampling accuracy and cleanliness of the entire liquid circuit system. Attached Figure Description

[0023] Figure 1 This is a schematic diagram of the hydraulic system of the pusher of this utility model.

[0024] in:

[0025] 100. Puncture needle; 101. Sampling needle; 200. Plunger pump; 201. P1 power pump; 202. P2 power pump; 300. Common pipeline; 301. First sampling pipeline; 302. Second sampling pipeline; 303. Sampling pipeline; 304. First cleaning pipeline; 305. Second cleaning pipeline; 306. First waste liquid pipeline; 307. Second waste liquid pipeline; 308. Third waste liquid pipeline; 501. V1 valve; 502. V2 valve; 503. V3 valve; 504. V4 valve; 505. V5 valve; 506. V6 valve; 700. Diluent tank; 701. Cleaning tank; 702. Waste liquid tank. Detailed Implementation

[0026] In order to better understand the technical means of this utility model and to implement it in accordance with the contents of the specification, the specific embodiments of this utility model will be further described in detail below with reference to the accompanying drawings and examples. The following examples are used to illustrate this utility model, but are not intended to limit the scope of this utility model.

[0027] like Figure 1 As shown, this utility model provides a liquid circuit system for a tablet pusher, including a sampling unit, a sample addition unit, and a cleaning unit.

[0028] The sampling unit is used to accurately aspirate sample reagents (such as blood, body fluids, etc.), and includes a puncture needle 100, a sampling line, a common line 300, a V1 valve 501, a V2 valve 502, and a plunger pump 200 for transporting sample reagents; wherein, the sampling line includes a first sampling line 301 and a second sampling line 302.

[0029] One end of the first sampling line 301 is connected to the puncture needle 100, and the other end of the first sampling line 301 is connected to the second sampling line 302. The other end of the second sampling line 302 (sample reagent output end) is connected to the common line 300, and the other end of the common line 300 is connected to the top working interface of the plunger pump 200.

[0030] The first sampling pipeline 301 is equipped with a V1 valve 501 to control its connection or disconnection, and the second sampling pipeline 302 is equipped with a V2 valve 502 to control its connection or disconnection.

[0031] The puncture needle 100 can be inserted into the sample reagent storage tube or cleaning tank 701 under the drive of the sampling drive structure (not shown) in the slide pusher.

[0032] The sample dispensing unit is used to dispense sample reagents onto a glass slide (not shown). It includes a dispensing needle 101, a dispensing line 303, and a V3 valve 503. The dispensing needle 101 is used to perform the dispensing operation. Driven by the dispensing drive structure (not shown) in the slide pusher, it can extend into the cleaning tank 701 or move above the glass slide.

[0033] One end of the sample addition pipeline 303 is connected to the connection point where the second sampling pipeline 302 and the common pipeline 300 are connected. That is, one end of the sample addition pipeline 303, one end of the second sampling pipeline 302 and one end of the common pipeline 300 are connected to each other and intersect at the same point. The sample addition pipeline 303 is equipped with a V3 valve 503 to control its connection or blockage.

[0034] In this invention, valves V1, V2, and V3 are preferably pinch valves. These valves use an external actuator (such as a cam or piston) to squeeze or release the tubing to open or close the flow path, effectively preventing sample reagent loss and contamination during transfer. Pinch valves are conventional existing technology, and their specific structure will not be described here. A plunger pump is used to increase the delivery power of the sample reagents. Its piston stroke can be precisely controlled, enabling precise liquid aspiration and dispensing of the sample reagents. This is also conventional existing technology, and its specific structure will not be described here.

[0035] The cleaning unit is used to clean the sampling unit, sample dispensing unit, plunger pump and related flow paths to ensure system cleanliness.

[0036] The cleaning unit includes a first cleaning pipeline 304, a second cleaning pipeline 305, a V4 valve 504, a V5 valve 505, a V6 valve 506, a P1 power pump 201, a diluent tank 700, two cleaning tanks 701, a first waste liquid pipeline 306, a second waste liquid pipeline 307, a third waste liquid pipeline 308, a P2 power pump 202, and a waste liquid tank 702.

[0037] One end of the first cleaning pipeline 304 is connected to the intersection of the first sampling pipeline 301 and the second sampling pipeline 302, and the other end of the first cleaning pipeline 304 is connected to the diluent tank 700. The diluent tank contains diluent for cleaning the pipeline. A P1 power pump 201 is provided on the first cleaning pipeline 304. A V4 valve 504 is provided on the first cleaning pipeline 304, on the side of the P1 power pump 201 away from the diluent tank 700, to control its connection or disconnection. The P1 power pump 201 is used to provide power for the diluent to be transported.

[0038] A second cleaning line 305 is connected to the first cleaning line 304, located between the P1 power pump 201 and the V4 valve 504. The other end of the second cleaning line 305 is connected to another working port on one side of the plunger pump 200, thereby injecting diluent into the pump chamber of the plunger pump 200. The second cleaning line 305 is equipped with a V5 valve 505 to control its connection or disconnection.

[0039] The P1 power pump of this invention is a peristaltic pump. The diluent only flows through the pipeline, and the pump body does not come into contact with the diluent, thereby avoiding the risk of contamination. It is an existing technology and has the advantages of easy maintenance and pollution prevention. It is suitable for diluents with large flow rates.

[0040] In this invention, both the V4 and V5 valves are two-way diaphragm valves. The diaphragm valve opens or blocks the flow channel in the valve cavity by the up-and-down movement of the internal elastic diaphragm. It has high sealing performance and is suitable for high-frequency and reliable switching control of cleaning fluid circuits.

[0041] Two cleaning tanks 701 are located below the puncture needle 100 and the sampling needle 101, respectively. Both cleaning tanks have drain ports at their bottoms. One drain port connects to the first waste liquid pipeline 306, and the other drain port of the other cleaning tank 701 connects to the second waste liquid pipeline 307. The other ends of the first and second waste liquid pipelines 306 and 307 extend towards each other and connect to a V6 valve 506. One end of a third waste liquid pipeline 308 is connected to the V6 valve 506, and the other end of the third waste liquid pipeline 308 connects to a waste liquid tank 702. A P2 power pump 202 is installed on the third waste liquid pipeline 308, positioned between the V6 valve and the waste liquid tank 702, and is used to draw waste liquid from the cleaning tank 701 into the waste liquid tank 702. The V6 valve is a two-position three-way diaphragm valve, which can selectively connect one of the cleaning tanks to the third waste liquid pipeline 308.

[0042] The P2 power pump of this invention is responsible for extracting mixed waste liquid containing residual sample reagents and diluents. Its internal cleanliness is very important. Therefore, the P2 power pump of this invention is preferably a diaphragm pump. Its internal isolation design ensures that the pump's mechanical parts (such as motors and connecting rods) will not come into contact with the waste liquid, thereby fundamentally avoiding the risk of waste liquid back-contaminating the system or the next sample.

[0043] The operation process of this utility model is as follows:

[0044] Emptying:

[0045] The sampling unit is emptied, valves V3, V4 and V5 are closed, valves V1 and V2 are opened, and the plunger pump 200 is started. It drives the puncture needle 100 to draw in a predetermined amount of air to empty the sampling pipeline and the diluent in the puncture needle. The emptied diluent is temporarily stored in the pump chamber of the plunger pump 200.

[0046] sampling:

[0047] Keep valves V3, V4, and V5 closed, and valves V1 and V2 open. The sampling drive structure (not shown) drives the puncture needle 100 to puncture into the sample reagent storage tube. The plunger pump 200 drives the puncture needle 100 to draw a certain amount of sample reagent. The sampling drive structure drives the puncture needle to pull out of the sample reagent storage tube.

[0048] Sample and reagent transfer:

[0049] Keep valves V3, V4, and V5 closed, and valves V1 and V2 open. The plunger pump 200 transfers the sample reagents drawn up through the first sampling line and the second sampling line into the common line 300.

[0050] At this point, the diluent produced in the above evacuation step will not contaminate the sample reagent because there is an air gap between it and the sample reagent.

[0051] Cleaning of the glass slide and sampling unit after sample addition:

[0052] The plunger pump 200 pushes the sample into the sample application line from the common line 300. At the same time, the diluent in the sample application line and the sample needle is discharged into the cleaning tank. After the diluent is discharged, the sample application drive structure (not shown) moves the sample needle 101 above the glass slide. At the same time, the V2 and V5 valves are closed, and the V1, V3, and V4 valves are opened. The plunger pump 200 transfers the sample reagent in the common line to the sampling line and the sample needle in sequence, and then drops it onto the surface of the glass slide.

[0053] Simultaneously, the sampling drive structure moves the puncture needle into the cleaning tank, and the P1 power pump 201 starts, drawing diluent from the diluent tank 700 and flowing out through the first cleaning pipeline to clean the first sampling pipeline 301, the second sampling pipeline 302 near the V1 valve, and the puncture needle. The cleaned diluent flows into its corresponding cleaning tank, the V6 valve opens the first waste liquid pipeline 306, and the P2 power pump 202 starts, drawing the waste liquid in the cleaning tank into the waste liquid tank 702. After cleaning is completed, the sampling drive structure drives the puncture needle to reset.

[0054] Cleaning of the sample dispensing unit, common piping, and plunger pump:

[0055] When valves V1 and V5 are closed, valves V2, V3, and V4 are opened, and valve V6 is used to connect the second waste liquid pipeline 307, power pump P1 201 is started, which draws the diluent from the diluent tank 700 and flows out through the first cleaning pipeline to clean the second sampling pipeline, the sample addition pipeline, and the sample addition needle in sequence; the sample addition drive structure (not shown) drives the sample addition needle to move into its corresponding cleaning tank, power pump P2 202 is started, and the waste liquid in the cleaning tank is drawn into the waste liquid tank 702;

[0056] After the scheduled time, open valves V5 and V3, close valves V2 and V4, start power pump P1 201, draw diluent from diluent tank 700, and the diluent flows out through the second cleaning line to clean the plunger pump, common line, sample dispensing line and sample dispensing needle in sequence.

[0057] The above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. It should be noted that for those skilled in the art, several improvements and modifications can be made without departing from the technical principles of the present utility model, and these improvements and modifications should also be considered within the protection scope of the present utility model.

Claims

1. A hydraulic system for a pusher, characterized in that, include: The sampling unit includes a puncture needle (100) and a sampling tubing connected to the puncture needle. The output end of the sampling tubing is connected to a common tubing (300). The sampling tubing is provided with a V1 valve (501) and a V2 valve (502) at intervals to control its on / off state. The other end of the common tubing (300) is connected to a working port on a plunger pump (200). The sampling unit includes a sampling needle (101) and a sampling tubing (303) connected to the sampling needle. The input end of the sampling tubing is connected to the output end of the common tubing (300) and the sampling tubing. The sampling tubing (303) is provided with a V3 valve (503) to control its on / off state. The cleaning unit includes a first cleaning pipeline (304), one end of which is connected to the sampling pipeline and located between valves V1 (501) and V2 (502), and the other end of which is connected to the diluent tank (700). A P1 power pump (201) for providing power to transport the diluent is provided on the first cleaning pipeline (304), and a V4 valve (504) for controlling its on / off state is provided on the first cleaning pipeline (304); a second cleaning pipeline (305), one end of which is connected to the first cleaning pipeline (304) and located between valve V4 (504) and pump P1 (201), and the other end of which is connected to another working port on the plunger pump (200); a V5 valve (505) for controlling its on / off state is provided on the second cleaning pipeline (305).

2. The hydraulic system of a pusher according to claim 1, characterized in that, The cleaning unit also includes two cleaning tanks (701), which are respectively placed below the puncture needle (100) or the sample application needle (101); One of the cleaning tanks (701) is connected to a first waste liquid pipeline (306), and the other cleaning tank (701) is connected to a second waste liquid pipeline (307). The other ends of the first waste liquid pipeline and the second waste liquid pipeline extend toward each other and are connected to a V6 valve (506). The V6 valve is connected to a third waste liquid pipeline (308). The third waste liquid pipeline is connected to the waste liquid tank (702). A power pump (202) for providing power to transport waste liquid in the cleaning tank (701) is provided on the third waste liquid pipeline and between the V6 valve and the waste liquid tank. The V6 valve can switch and selectively connect one of the cleaning tanks to the third waste liquid pipeline.

3. The hydraulic system of a pusher according to claim 2, characterized in that, The sampling pipeline includes a first sampling pipeline (301) and a second sampling pipeline (302); One end of the first sampling line (301) is connected to the puncture needle (100), and the other end is connected to one end of the second sampling line (302). The V1 valve is located on the first sampling line, and the V2 valve is located on the second sampling line. One end of the first cleaning line (304) is connected to the junction of the first sampling line and the second sampling line. One end of the sample addition pipeline (303) is connected to the other end of the second sampling pipeline (302), and one end of the common pipeline is connected to the junction of the sample addition pipeline and the second sampling pipeline.

4. The hydraulic system of a pusher according to claim 3, characterized in that, The V1 valve (501), V2 valve (502) and V3 valve (503) are all clamp valves.

5. The hydraulic system of a pusher according to claim 3, characterized in that, The V4 and V5 valves are two-way diaphragm valves, and the V6 valve is a two-position three-way diaphragm valve.

6. The hydraulic system of a pusher according to claim 3, characterized in that, The P1 power pump (201) is a peristaltic pump.

7. The hydraulic system of a pusher according to claim 3, characterized in that, The P2 power pump (202) is a diaphragm pump.

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