PCR module hot cover structure sealing module

Abstract

The utility model provides a PCR module hot cover structure seal module, including movable frame, compression drive board, the heating cover plate assembly of connecting in the lower extreme of compression drive board, the fixed setting of movable frame has the sliding block guide plate, is provided with the down -pressing drive mechanism between the sliding block guide plate and compression drive board, when PCR hot cover module is by open state and is switched to closed state, the down -pressing drive mechanism drives heating cover plate assembly to move to the direction of PCR reaction tube, is provided with the second elastic connecting mechanism between compression drive board and heating cover plate assembly. In the utility model, heating cover plate assembly is driven to move to the direction of PCR reaction tube through the down -pressing drive mechanism, thereby provides stable compression drive force for heating cover plate assembly, the second elastic connecting mechanism exerts stable elastic pressure to heating cover plate assembly, adjusts contact pressure through the elastic force self -adaptation, makes heating cover plate assembly and PCR reaction tube keep stable and is pasted, avoids local pressure shortage or excessive extrusion, promotes the stability of contact pressure.

Description

Technical Field

[0001] This utility model relates to the field of biological detection technology, and in particular to a PCR module heat-sealing module. Background Technology

[0002] The PCR heat-sealing module is a key component of PCR equipment. Its main function is to apply a certain temperature to the top of the reaction tube during the PCR reaction and form a thermal vapor barrier to prevent the loss of reaction solution due to heating and evaporation, while avoiding cross-contamination between samples and ensuring the integrity of the reaction system.

[0003] Existing PCR hot-lid modules have an unstable contact pressure with PCR reaction tubes during use, resulting in poor sealing of the PCR reaction tubes. This makes it easy for aerosols generated by the evaporation of the reaction solution to spread into the surrounding environment and cause cross-contamination of other reaction samples. Summary of the Invention

[0004] The purpose of this invention is to address the shortcomings of existing technologies and provide a PCR module heat-sealing module.

[0005] The purpose of this utility model is achieved through the following technical solution: a PCR module hot cover structure sealing module, including a movable frame, a pressing drive plate, and a heating cover assembly connected to the lower end of the pressing drive plate. A slider guide plate is fixedly installed on the movable frame, and a downward driving mechanism is provided between the slider guide plate and the pressing drive plate. When the PCR hot cover module switches from an open state to a closed state, the downward driving mechanism drives the heating cover assembly to move towards the PCR reaction tube. A second elastic connection mechanism is provided between the pressing drive plate and the heating cover assembly. When the PCR hot cover module is in a closed state, the second elastic connection mechanism applies a downward elastic force to the heating cover assembly.

[0006] Preferably, the pressing drive mechanism includes a groove on the slider guide plate, a slider slidably connected in the groove, and a first elastic connection mechanism between the slider and the pressing drive plate; the first elastic connection mechanism applies an upward elastic force to the pressing drive plate; rollers are respectively provided on both sides of the slider guide plate, and a boss corresponding to the roller is provided on the pressing drive plate, with an inclined surface and a top plane on the boss, the top plane being connected to the high end of the inclined surface; when the PCR hot cap module is in a closed state, the roller is located on the top plane of the boss.

[0007] Preferably, the first elastic connection mechanism includes a first limiting screw, a first spring, and a spring hole disposed on the slider. The first limiting screw passes through the spring hole on the slider and is connected to the clamping drive plate. The first spring is disposed in the spring hole, and the two ends of the first spring are in contact with the slider and the first limiting screw, respectively.

[0008] Preferably, a limiting pressure plate for limiting the slider is provided above the slide groove.

[0009] Preferably, the second elastic connection mechanism includes a second limiting screw, a second spring, and a through hole disposed on the pressing drive plate. The second limiting screw passes through the through hole on the pressing drive plate and is connected to the heating cover plate assembly. The second spring is disposed between the heating cover plate assembly and the pressing drive plate.

[0010] Preferably, the heating cover assembly includes an upper cover plate, a lower cover plate, and a heating component, with the heating component disposed between the upper cover plate and the lower cover plate.

[0011] Preferably, the heating component is a silicone heating plate.

[0012] Preferably, the movable frame is provided with a lead screw nut.

[0013] Preferably, an outer cover plate is provided above the slider guide plate.

[0014] The beneficial effects of this utility model are as follows: In this utility model, during the process of switching the PCR heating cover module from the open state to the closed state, the heating cover assembly is driven to move towards the PCR reaction tube by the pressing drive mechanism, thereby providing a stable pressing drive force for the heating cover assembly, thus achieving reliable pressure contact between the heating cover assembly and the PCR reaction tube and ensuring the sealing effect; the second elastic connection mechanism applies stable elastic pressure to the heating cover assembly, and the contact pressure is adaptively adjusted by the elastic force, so that the heating cover assembly and the PCR reaction tube remain stably attached, avoiding insufficient local pressure or excessive squeezing, effectively improving the stability of the contact pressure, preventing aerosol leakage caused by the evaporation of the reaction liquid, and reducing cross-contamination between samples from the source. Attached Figure Description

[0015] Figure 1 This is a schematic diagram of the PCR hot cap module in the closed state.

[0016] Figure 2 This is a schematic diagram of the PCR hot cap module in the open state.

[0017] Figure 3 This is a schematic diagram of the PCR hot cap module.

[0018] Figure 4 This is an exploded view of the PCR hot cap module.

[0019] Figure 5 This is a schematic diagram showing the fit between the clamping drive plate and the heating cover plate assembly.

[0020] Figure 6This is a schematic diagram showing the connection between the pressure drive plate, the heating cover plate assembly, and the slider.

[0021] Figure 7 This is a top view of the connection between the pressure drive plate, the heating cover plate assembly, and the slider.

[0022] Figure 8 for Figure 7 A cross-sectional view along the AA direction.

[0023] In the diagram: 1. Motor, 2. Guide rail, 3. Lead screw, 4. PCR reaction tube, 5. Outer cover plate, 6. Moving frame, 6-1. Lead screw nut, 7. Slider guide plate, 7-1. Slide groove, 7-2. Roller, 8. Slider, 8-1. Spring hole, 9. Limiting plate, 10. First limiting screw, 11. First spring, 12. Pressing drive plate, 12-1. Boss, 12-1a. Top plane, 12-1b. Inclined surface, 13. Upper cover plate, 14. Lower cover plate, 15. Heating assembly, 16. Second limiting screw, 17. Second spring. Detailed Implementation

[0024] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. All other embodiments obtained by those skilled in the art based on the embodiments of the present utility model are within the protection scope of the present utility model.

[0025] like Figures 1 to 8 As shown, a PCR module hot cover structure sealing module includes a movable frame 6, a pressing drive plate 12, and a heating cover assembly connected to the lower end of the pressing drive plate 12. A slider guide plate 7 is fixedly installed on the movable frame 6, and a downward driving mechanism is provided between the slider guide plate 7 and the pressing drive plate 12. When the PCR hot cover module switches from an open state to a closed state, the downward driving mechanism drives the heating cover assembly to move towards the PCR reaction tube 4. A second elastic connection mechanism is provided between the pressing drive plate 12 and the heating cover assembly. When the PCR hot cover module is in a closed state, the second elastic connection mechanism applies a downward elastic force to the heating cover assembly.

[0026] In this invention, the movable frame 6 is connected to the drive mechanism on the PCR equipment, and the drive mechanism drives the movable frame 6 to move horizontally. During the process of the PCR heated cover module switching from the open state to the closed state, the pressing drive mechanism drives the heated cover assembly to move towards the PCR reaction tube 4, thereby providing a stable pressing driving force for the heated cover assembly, thus achieving reliable pressure contact between the heated cover assembly and the PCR reaction tube 4, and ensuring a sealing effect.

[0027] The second elastic connection mechanism applies stable elastic pressure to the heating cover assembly. Through adaptive adjustment of the contact pressure using elastic force, it ensures a stable fit between the heating cover assembly and the PCR reaction tube 4, preventing insufficient local pressure or excessive compression. This effectively improves the stability of the contact pressure, strengthens the sealing of the thermal vapor barrier, and prevents aerosol leakage caused by the evaporation of the reaction liquid, thus reducing cross-contamination between samples at its source. Furthermore, the elastic force generated by the second elastic connection mechanism provides excellent buffering, preventing damage to the PCR reaction tube 4 caused by hard contact, while also offsetting the effects of thermal expansion and contraction due to temperature changes, maintaining pressure stability throughout the entire process.

[0028] Specifically, the pressing drive mechanism includes a groove 7-1 set on the slider guide plate 7, a slider 8 slidably connected in the groove 7-1, and a first elastic connection mechanism between the slider 8 and the pressing drive plate 12; the first elastic connection mechanism applies an upward elastic force to the pressing drive plate 12; rollers 7-2 are respectively set on both sides of the slider guide plate 7, and the pressing drive plate 12 is provided with a boss 12-1 corresponding to the rollers 7-2. The boss 12-1 is provided with an inclined surface 12-1b and a top plane 12-1a, and the top plane 12-1a is connected to the high end of the inclined surface 12-1b; when the PCR hot cap module is in a closed state, the rollers 7-2 are located on the top plane 12-1a of the boss 12-1.

[0029] The length direction of the groove 7-1 is consistent with the overall horizontal movement direction of the PCR hot cap module. The slider 8 is embedded in the groove 7-1 of the slider guide plate 7, and the slider 8 can move horizontally along the groove 7-1. When the PCR hot cap module switches from the open state to the closed state, relative movement occurs between the pressure drive plate 12 and the slider guide plate 7, at which time the slider 8 will move to one end of the groove 7-1; similarly, when the PCR hot cap module switches from the closed state to the open state, relative movement also occurs between the pressure drive plate 12 and the slider guide plate 7, at which time the slider 8 will move to the other end of the groove 7-1; the relative movement stroke between the pressure drive plate 12 and the slider guide plate 7 is limited by the cooperation between the slider 8 and the groove 7-1.

[0030] The first elastic connecting mechanism connects the slider 8 and the pressing drive plate 12. The first elastic connecting mechanism always applies an upward elastic force to the pressing drive plate 12, which acts as a reset mechanism for the pressing drive plate 12. During the closing process of the PCR hot cover module, the roller 7-2 moves along the inclined surface 12-1b on the boss 12-1 to the top plane 12-1a. The roller 7-2 and the boss 12-1 cooperate to generate a downward driving force, which drives the pressing drive plate 12 downward, thereby moving the heating cover assembly towards the PCR reaction tube 4, achieving a sealing and pressing of the PCR reaction tube 4. At this time, the upward elastic force generated by the first elastic connecting mechanism and the downward driving force are balanced. When the PCR hot cover module is opened, the first elastic connecting mechanism releases the elastic force, which drives the pressing drive plate 12 upward to reset.

[0031] The first elastic connection mechanism includes a first limiting screw 10, a first spring 11, and a spring hole 8-1 disposed on the slider 8. The first limiting screw 10 passes through the spring hole 8-1 on the slider 8 and is connected to the pressing drive plate 12. The first spring 11 is disposed in the spring hole 8-1, and the two ends of the first spring 11 are in contact with the slider 8 and the first limiting screw 10, respectively.

[0032] A limiting plate 9 is provided above the slide groove 7-1 to limit the slider 8. The limiting plate 9 is used to limit the slider 8 in the vertical direction to prevent the slider 8 from disengaging from the slide groove 7-1.

[0033] The second elastic connection mechanism includes a second limiting screw 16, a second spring 17, and a through hole provided on the pressing drive plate 12. The second limiting screw 16 passes through the through hole on the pressing drive plate 12 and is connected to the heating cover assembly. The second spring 17 is provided between the heating cover assembly and the pressing drive plate 12.

[0034] The heating cover assembly includes an upper cover plate 13, a lower cover plate 14, and a heating component 15, which is disposed between the upper cover plate 13 and the lower cover plate 14.

[0035] In this embodiment, the heating component 15 is a silicone heating plate. A temperature sensor is installed in the heating component 15 to detect the temperature of the heating component 15 in real time and upload the detected temperature data to the control system of the PCR device. The control system then adjusts the heating temperature of the heating component 15 based on feedback to achieve temperature stability.

[0036] An outer cover plate 5 is provided above the slider guide plate 7. The outer cover plate 5 provides a certain degree of protection for the PCR hot cover module.

[0037] A lead screw nut 6-1 is provided on the movable frame 6. The lead screw nut 6-1 cooperates with the drive mechanism on the PCR equipment to realize the overall movement of the PCR hot cover module. In this embodiment, the drive mechanism on the PCR equipment includes a motor 1 and a lead screw 3 connected to the motor 1. The lead screw 3 is threadedly engaged with the lead screw nut 6-1 on the movable frame 6. The two sides of the movable frame 6 are connected to the guide rails 2 on the PCR equipment, and the movement of the movable frame 6 is guided by the guide rails 2. The motor 1 drives the lead screw 3 to rotate, and when the lead screw 3 rotates, it drives the PCR hot cover module to move along the direction of the guide rail 2, thereby realizing the switching between the open and closed states of the PCR hot cover module.

[0038] This utility model is not limited to the above-described preferred embodiments. Anyone can derive other forms of products under the guidance of this utility model. However, regardless of any changes made in their shape or structure, any technical solution that is the same as or similar to this application falls within the protection scope of this utility model.

Claims

1. A PCR module heat-sealing module, characterized in that, The device includes a movable frame, a pressing drive plate, and a heating cover assembly connected to the lower end of the pressing drive plate. A slider guide plate is fixedly mounted on the movable frame, and a pressing drive mechanism is provided between the slider guide plate and the pressing drive plate. When the PCR heating cover module switches from an open state to a closed state, the pressing drive mechanism drives the heating cover assembly to move towards the PCR reaction tube. A second elastic connection mechanism is provided between the pressing drive plate and the heating cover assembly. When the PCR heating cover module is in the closed state, the second elastic connection mechanism applies a downward elastic force to the heating cover assembly.

2. The PCR module heat-sealing module according to claim 1, characterized in that, The pressing drive mechanism includes a groove on the slider guide plate and a slider slidably connected in the groove. A first elastic connection mechanism is provided between the slider and the pressing drive plate. The first elastic connection mechanism applies an upward elastic force to the pressing drive plate. Rollers are provided on both sides of the slider guide plate. The pressing drive plate is provided with a boss corresponding to the roller. The boss is provided with an inclined surface and a top plane. The top plane is connected to the high end of the inclined surface. When the PCR hot cover module is in a closed state, the roller is located on the top plane of the boss.

3. A PCR module heat-sealing module according to claim 2, characterized in that, The first elastic connection mechanism includes a first limiting screw, a first spring, and a spring hole disposed on the slider. The first limiting screw passes through the spring hole on the slider and is connected to the clamping drive plate. The first spring is disposed in the spring hole, and the two ends of the first spring are in contact with the slider and the first limiting screw, respectively.

4. A PCR module heat-sealing module according to claim 2, characterized in that, A limiting pressure plate for limiting the slider is provided above the slide groove.

5. A PCR module heat-sealing module according to claim 1, characterized in that, The second elastic connection mechanism includes a second limiting screw, a second spring, and a through hole disposed on the pressing drive plate. The second limiting screw passes through the through hole on the pressing drive plate and is connected to the heating cover plate assembly. The second spring is disposed between the heating cover plate assembly and the pressing drive plate.

6. A PCR module heat-sealing module according to claim 1, characterized in that, The heating cover assembly includes an upper cover plate, a lower cover plate, and a heating component, which is disposed between the upper cover plate and the lower cover plate.

7. A PCR module heat-sealing module according to claim 6, characterized in that, The heating component is a silicone heating plate.

8. A PCR module heat-sealing module according to claim 1, characterized in that, The movable frame is equipped with a lead screw and nut.

9. A PCR module heat-sealing module according to claim 1, characterized in that, An outer cover plate is provided above the slider guide plate.

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