Miniature Flash Radiotherapy Equipment

The miniature Flash radiotherapy device addresses the limitations of conventional treatments by using a 3D scanning unit and controlled electron beams for precise, automated treatment of superficial lesions, ensuring effective therapy with reduced tissue damage.

FR3138043B1Active Publication Date: 2026-01-02SUN YAT SEN UNIV
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Patent Information

Application Number
FR2023007108
Authority / Receiving Office
FR · FR
Patent Type
Patents
Current Assignee / Owner
Priority Date
2022-07-22
Filing Date
2023-07-04
Publication Date
2026-01-02
Estimated Expiration
2043-07-04

AI Technical Summary

Technical Problem

Conventional radiotherapy for diseases like superficial human body hyperplasia, skin cancer, and hemangioma causes significant damage to normal tissues, nuclide drug patches are expensive and difficult to prepare, and have a limited application range with a long treatment duration.

Method used

A miniature Flash radiotherapy device comprising a 3D scanning unit, microwave electron gun, and beam transmission unit, which uses electron beams with controlled energy and dose to perform targeted scanning on disease lesions, enabling high-precision, automated Flash radiotherapy.

Benefits of technology

The device provides effective treatment for superficial lesions with minimal damage to normal tissues, offering equivalent or superior tumor-fighting effects while being compact, portable, and easier to use than existing high-energy equipment.

✦ Generated by Eureka AI based on patent content.

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Abstract

Miniature Flash Radiotherapy Equipment The present invention discloses miniature Flash radiotherapy equipment, comprising: a 3D scanning unit (10) used to obtain 3D data of a target area, said 3D data being used to determine the energy of an electron beam and to determine a target scanning trajectory in the target region using the electron beam; a microwave electron gun (20) used to generate an electron beam current having an energy and dose adapted to the 3D data; and a beam transmission unit (30) used to transmit the electron beam generated by the microwave electron gun (20) and enable the electron beam to perform the scan in the target area along the target trajectory. Figure to be published with the abbreviation: Figure 2
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Description

Title of the invention: Miniature Flash Radiotherapy Equipment technical field

[0001] The present invention relates to the technical field of radiotherapy equipment, and in particular to a miniature Flash radiotherapy device. PRIORITY OF THE TECHNOLOGY

[0002] Diseases such as superficial human body hyperplasia, skin cancer, and hemangioma are generally treated in the prior art using conventional radiotherapy or nuclide drug patches. However, conventional radiotherapy causes significant damage to a patient's normal tissues. Nuclide drug patches are highly dependent on nuclide drugs, which are difficult to prepare and expensive. Nuclide drug patches also have a long treatment duration (one treatment lasts 2 to 3 days, and a cycle lasts approximately one month). Furthermore, nuclide drug patches carry a risk of diffusion and therefore have a limited range of applications. CONTENTS OF THE INVENTION

[0003] In view of this, the present invention relates to a miniature Flash radiotherapy equipment, a method and a miniature flash radiation control device, and associated equipment, so as to implement Flash radiotherapy on disease lesions, such as superficial hyperplasia of the human body, skin cancer and hemangioma.

[0004] To achieve the aforementioned objective, a first aspect of the present invention relates to a miniature Flash radiotherapy device, comprising:

[0005] a 3D (three-dimensional) scanning unit which is used to obtain 3D data of a target area, said 3D data is used to determine the energy of an electron beam and to determine a target scanning trajectory in the target region using the electron beam;

[0006] a microwave electron gun, which is used to generate an electron beam current having an energy and dose suitable for 3D data, the energy of said electron beam being less than 2 MeV; and

[0007] a beam transmission unit, which is used to transmit the electron beam generated by the microwave electron gun and enable the electron beam to perform the scan in the target area along the target trajectory.

[0008] Preferably, the beam transmission unit comprises a vacuum beam pipeline and two sets of secondary magnets; the vacuum beam pipeline has a diameter of 10 cm and is used to transmit the electron beam; the secondary magnets are used to control a scanning position of the electron beam.

[0009] Preferably, a separation film is arranged at one end of the vacuum beam pipeline; the separation film is used to separate a vacuum environment inside the vacuum beam pipeline from an air environment outside the vacuum beam pipeline.

[0010] Preferably, the separation film is a titanium film, or a beryllium film with a thickness of 100 pm.

[0011] Preferably, a beam current intensity measurement unit is arranged at a rear part of the beam transmission unit, which is used to determine a dose of the electron beam passing through the vacuum beam pipeline, said dose being used to feed back and control the dose of the electron beam generated by the microwave electron gun.

[0012] Preferably, the frequency of the electron beam current is 50 Hz; and the single pulse charge for the electron beam current is 1 nC.

[0013] Preferably, the equipment also comprises:

[0014] a beam control unit, which is used to control, according to 3D data and a type of disease at the level of the target area, the microwave electron gun and the beam transmission unit in order to carry out the scanning in the target area according to the target trajectory.

[0015] Preferably, the process by which the beam control unit controls, according to 3D data and a disease type at the level of the target area, the microwave electron gun and the beam transmission unit in order to perform the scan in the target area along the target trajectory, comprises the following steps:

[0016] if the type of disease is a proliferative keloid, a keloid, a cavernous cutaneous hemangioma, a common wart, localized refractory eczema, neurodermatitis or psoriasis, according to the 3D data, determine if the thickness of the diseased tissue in the target area is less than 3 mm;

[0017] if the thickness is less than 3 mm, to control said microwave electron gun to emit an electron beam with an energy of less than 1 MeV, and to control said beam transmission unit to perform the scanning in the target area along the target trajectory using the electron beam; and

[0018] if the thickness is not less than 3 mm, command said microwave electron gun to emit an electron beam with an energy greater than 1 MeV and less than 2 MeV, and command said beam transmission unit to perform the scanning in the target area along the target trajectory using the electron beam.

[0019] Preferably, the process of controlling the beam transmission unit to perform the scanning in the target area along the target trajectory using the electron beam comprises the following steps:

[0020] control the secondary magnets so that they move along said target trajectory, to carry out the scanning of the electron beam in the target area along the target trajectory.

[0021] Preferably, a macro-pulse duration of the electron beam generated by the microwave electron gun is set in a range of 10 nanoseconds to 100 milliseconds.

[0022] A second aspect of the present invention relates to a method for controlling miniature flash radiation, comprising:

[0023] obtaining 3D data of a target area, the 3D data being used to determine the energy of an electron beam and to determine a target scanning trajectory in the target region using the electron beam; and

[0024] control, according to 3D data and a type of disease at the level of the target area, the microwave electron gun and the beam transmission unit in order to carry out the scan in the target area along the target trajectory.

[0025] A third aspect of the present invention relates to a miniature flash radiation control device, comprising:

[0026] a data acquisition unit, configured to obtain 3D data of a target area, the 3D data being used to determine the energy of an electron beam and to determine a target scanning trajectory in the target region using the electron beam; and

[0027] a scanning control unit, configured to control, according to 3D data and a type of disease at the level of the target area, a microwave electron gun and a beam transmission unit in order to perform the scanning in the target area along the target trajectory.

[0028] Preferably, the process by which the beam control unit controls, according to 3D data and a disease type at the level of the target area, the microwave electron gun and the beam transmission unit in order to perform the scan in the target area along the target trajectory, comprises the following steps:

[0029] if the type of disease is a hypertrophic scar, a keloid, a cavernous cutaneous hemangioma, a common wart, localized refractory eczema, atopic dermatitis or psoriasis, according to the 3D data, determine if the thickness of the diseased tissue in the target area is less than 3 mm;

[0030] if the thickness is less than 3 mm, order said microwave electron gun to emit an electron beam with an energy of less than 1 MeV, and to control said beam transmission unit in order to perform the scanning in the target area along the target trajectory using the electron beam; and

[0031] if the thickness is not less than 3 mm, command said microwave electron gun to emit an electron beam with an energy greater than 1 MeV and less than 2 MeV, and command said beam transmission unit to perform the scanning in the target area along the target trajectory using the electron beam.

[0032] Preferably, the process of controlling the beam transmission unit to perform the scanning in the target area along the target trajectory using the electron beam comprises the following steps:

[0033] to control said secondary magnets so that they move along said target trajectory, to carry out the scanning of the electron beam in the target area along the target trajectory.

[0034] A fourth aspect of the present invention relates to a miniature flash radiation control device, comprising a memory and a processor;

[0035] The memory is configured to store programs; and

[0036] The processor is configured to execute programs in order to implement the various steps of the aforementioned miniature flash radiation control process.

[0037] A fifth aspect of the present invention relates to a storage medium that stores a computer program on it. The computer program, when executed by a processor, implements the various steps of the aforementioned miniature flash radiation control method.

[0038] According to the technical drawings, the present invention comprises a 3D scanning unit, a microwave electron gun, and a beam transmission unit. The 3D scanning unit is configured to obtain 3D data of a target area. This 3D data is used to determine the energy of an electron beam and to define a target scanning path within the target region using the electron beam. The 3D data may include information such as the thickness and location of a lesion in the target area. Depending on the lesion thickness, electron beams of different energies can be established, while a scanning target can be defined based on the lesion location information, thus determining the target scanning path. The microwave electron gun is configured to generate an electron beam current with an energy and dose adapted to the 3D data.The beam transmission unit is configured to transmit the electron beam generated by the microwave electron gun and allow the electron beam to scan the target area along the target trajectory. Since the energy, dose, and target trajectory of the electron beam are all determined according to the... Using 3D data, the entire electron beam scanning process can be highly automated, enabling the targeted delivery of Flash radiotherapy to disease foci such as superficial hyperplasia of the human body, skin cancer, and hemangioma, thereby inhibiting and treating hyperplastic tissue at the site of the lesions. Due to the relatively low energy required by these diseases, the various units are compactly combined in suitable configurations, and the entire system can be integrated into a small, portable form. BRIEF DESCRIPTION OF THE FIGURES

[0039] In order to illustrate more clearly the technical diagrams in the embodiments of the present invention or in the prior art, the drawings to be used in the description of the embodiments or the prior art are briefly presented below. It is evident that the drawings in the description below are only embodiments of the present invention, and a person skilled in the art can obtain other drawings based on the drawings provided without creative effort.

[0040] [Fig. 1] is a diagram of a miniature Flash radiotherapy device described in an embodiment of the present invention;

[0041] [Fig.2] is a schematic structural diagram of a miniature piece of equipment Flash radiotherapy described in an embodiment of the present invention;

[0042] [Fig.3] is a schematic structural diagram of a miniature piece of equipment Flash radiotherapy described in an embodiment of the present invention;

[0043] [Fig.4] is a schematic structural diagram of a miniature piece of equipment Flash radiotherapy described in an embodiment of the present invention;

[0044] [Fig. 5] is a schematic diagram of a miniature flash radiation control method described in an embodiment of the present invention;

[0045] [Fig.6] is a schematic of a miniature flash radiation control device described in an embodiment of the present invention; and

[0046] [Fig.7] is a diagram of a flash radiation control device miniature described in an embodiment of the present invention. DETAILED DESCRIPTION OF THE IMPLEMENTATION METHODS

[0047] The technical diagrams in the embodiments of the present invention are clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is evident that the described embodiments are only a part of the embodiments of the present invention, but not all of them. Based on the embodiments of the present invention, all other embodiments obtained by a person skilled in the art without creative effort fall within the scope of the present invention.

[0048] Flash radiotherapy, a key area of ​​international tumor radiotherapy research in recent years, injects the entire radiotherapy dose into a target area in a very short time (1 to 50 ms) using an ultra-high dose rate (generally greater than 40 Gy / s). An organism generates a flash effect after flash radiotherapy, and this effect can provide better protection for normal tissues without reducing the therapeutic effect of radiotherapy on tumors. The flash radiation phenomenon has been verified by various institutions, including Stanford University School of Medicine, Lausanne University Hospital, the Curie Institute, and others, in experiments with different animal models (mouse, cat, pig, and zebrafish), different tissues (skin, lungs, intestines and stomach, and brain), and different types of radiation (electrons, X-rays, and protons).Compared to traditional radiotherapy, Flash radiotherapy offers equivalent or superior tumor-fighting effects, less toxicity to normal tissues, and an immune-boosting benefit. Various types of equipment for delivering Flash radiotherapy have become available on the market.

[0049] However, existing equipment with the Flash radiotherapy function is all high-energy electron beam Flash radiotherapy equipment, which is intended for large internal organ tumors. This equipment is large, expensive, and complex to operate. Smaller, easy-to-use equipment is better suited for treating skin scars, skin cancer, hemangiomas, and other lesions on a superficial layer of a patient's body.

[0050] The following describes a miniature Flash radiotherapy device provided in one embodiment of the present invention. See [Fig. 1]. The miniature Flash radiotherapy device according to this embodiment of the present invention may comprise a 3D scanning unit 10, a microwave electron gun 20, and a beam transmission unit 30.

[0051] The 3D scanning unit 10 is configured to obtain 3D data from a target area. The 3D data is used to determine the energy of an electron beam and to determine a target scanning path in the target region using the electron beam.

[0052] The 3D scanning unit 10 can use contact-type 3D scanning technology. In particular, a detection probe is used to make contact with the surface of an object to obtain the coordinates of a touched point. In the scanning process, the surface of the object must be touched sequentially, point by point, so that a relatively high scanning accuracy is achieved, for example, up to 0.1 sq m.

[0053] In addition, the 3D scanning unit 10 can use an active non-contact 3D scanning technology, with a technical line comprising: a time-of-flight process (also called deep sensing technology, hereinafter referred to as TOF) and structured light.

[0054] The basic principle of TOF technology is similar to that of bats and dolphins, which emit "waves" towards a detected object, receive "waves" reflected by the detected object, and calculate the distance to the detected object based on the round-trip time of the "waves." Furthermore, TOF technology now allows for small modules, resulting in extremely high convenience.

[0055] Structured light technology is an application of a 3D scanning technology commonly used in industrial and manufacturing fields. Structured light 3D scanning technology is based on a principle of optical triangulation and involves an optical projector, a camera, and a computer system. One of its principles is as follows: a light source projects an image encoded according to a specific rule and mode onto the detected object, and this encoded pattern is modulated to deform into a shape of the object's surface. The structured light with this deformation is photographed by the camera at another position. A three-dimensional shape of the object can be determined based on a positional relationship between the camera and the projecting light source, and the degree of deformation of the structured light.There are point, linear, grid and surface structure lights, depending on the different light beams projected by the projector.

[0056] The structured light process offers the significant advantages of high precision and high speed, making it suitable for high-precision, short-range measurement. Due to its high precision and high resolution, structured light is a common technology currently applied in industry and manufacturing. Fixed and portable 3D scanning equipment is derived from it, utilizing different projection light sources, pattern types, and calculation methods. Compared to time-of-flight (TOF) technology, structured light has the disadvantage of not being suitable for long-range scanning, and the scanning effect is sensitive to environmental factors and the color of the material on the object's surface.

[0057] It is understood that lookup tables for lesion type, lesion thickness, and electron beam energy can be predefined according to specific treatment objectives of the miniature Flash radiotherapy equipment. After the 3D scanning unit scans a lesion thickness, the lookup table is consulted based on a pre-defined lesion type, or based on a lesion type scanned by the 3D scanning unit, which allows the electron beam energy to be determined.

[0058] In the scanning process, the 3D scanning unit 10 can obtain real-time anchor point location information, determine a target trajectory according to the anchor point location information and the target area, and command the electron beam to accurately scan a lesion region along the target trajectory.

[0059] The microwave electron gun 20 is configured to generate an electron beam current having an energy and dose adapted to the 3D data. More specifically, a control unit can obtain the 3D data from the 3D scanning unit 10 in real time, determine the energy and dose of the electron beam according to the 3D data, and then control, according to the energy and dose obtained, the microwave electron gun 20 in real time in order to generate the corresponding electron beam.

[0060] The microwave electron gun 20 may include a linear electron accelerator. A resonant cavity may be formed inside the linear electron accelerator. The resonator generates a high-voltage electric field moving forward along an axis under microwave excitation, and the electrons are continuously accelerated to gain energy. The higher the intensity of the electric field, the longer the acceleration distance and the greater the energy that the electrons can obtain. These high-energy electrons are directly extracted in the form of electron beams.

[0061] Different types of treatment schemes can be selected depending on the type of disease. More specifically, the electron beam energy and the corresponding treatment schemes are determined based on the type of disease and the depth of the lesion. For example, if it is a thicker skin cancer or hemangioma, the lesion can be scanned for coverage treatment with a 2 MeV electron beam; and if it is a scar or shallow psoriasis, the lesion can be scanned for coverage treatment with a 1 MeV or 500 keV electron beam.

[0062] The beam transmission unit 30 is configured to transmit the electron beam generated by the microwave electron gun 20 and enable the electron beam to scan the target area along the target trajectory. More specifically, the electron beam generated by the microwave electron gun 20 is transported to the injury region via the beam transmission unit 30. The control unit can command the beam transmission unit 30, so that the electron beam scans the target area along the target trajectory.

[0063] For example, the beam transmission unit 30 can be located at the level of a head of the miniature Flash radiotherapy equipment, and is equipped with beam deflection, target window switching, and beam leveling functions, beam collimation, measurement, and similar. A heat dissipation system can also be provided to achieve heat dissipation and cooling on the components of the microwave electron gun 20 that are likely to generate heat, such as an accelerating tube, a microwave source (a magnetron or a klystron) and a deflection magnet, to maintain stable operation of the equipment.

[0064] The present invention comprises a 3D scanning unit, a microwave electron gun, and a beam transmission unit. The 3D scanning unit is configured to obtain 3D data of a target area. This 3D data is used to determine the energy of an electron beam and to define a target scanning path within the target region using the electron beam. The 3D data may include information such as the thickness and location of a lesion in the target area. Depending on the lesion thickness, electron beams of different energies can be established, while a scanning target can be defined based on the lesion location information, thus determining the target scanning path. The microwave electron gun is configured to generate an electron beam current with an energy and dose adapted to the 3D data.The beam transmission unit is configured to transmit the electron beam generated by the microwave electron gun and allow the electron beam to scan the target area along the target trajectory. Since the energy, dose, and target trajectory of the electron beam are all determined based on 3D data, the entire electron beam scanning process can be highly automated, enabling the achievement of Flash radiotherapy objectives for disease foci such as superficial hyperplasia of the human body, skin cancer, and hemangioma.

[0065] In certain embodiments of the present invention, see [Fig. 2], the beam transmission unit 30 comprises a vacuum beam pipeline 31 and two sets of secondary magnets 32. The vacuum beam pipeline 31 has a diameter of 10 cm and is used to transmit the electron beam; and the secondary magnets 32 are used to control a scanning position of the electron beam. More specifically, the two sets of secondary magnets 32 control a scanning position of the electron beam in a transverse direction and a longitudinal direction respectively by changing the direction of execution of the electron beam.

[0066] For example, the vacuum beam pipeline 31 may include a titanium pump and a vacuum device. One of its functions is to maintain a high vacuum inside the vacuum beam pipeline 31 and at the electron gun. microwave 20 and other components, to avoid filament combustion, internal sparks, energy loss, and the like.

[0067] In certain embodiments of the present invention, a separation film is arranged at one end of the vacuum beam pipeline 31. The separation film is used to separate a vacuum environment inside the vacuum beam pipeline 31 from an air environment outside the vacuum beam pipeline.

[0068] In certain embodiments of the present invention, the separation film may be a titanium film or a beryllium film with a thickness of 100 µm. Titanium is a noble metal, characterized by low density, a high melting point, and good corrosion resistance. The beryllium film is characterized by being lighter than the titanium film, which means that vibrations can be faster and freer in a high dynamic range.

[0069] In certain embodiments of the present invention, see [Fig.3], a beam current intensity measuring unit 40 is arranged at a rear part of the beam transmission unit 30, and is configured to determine a dose of the electron beam passing through the vacuum beam pipeline 31, said dose being used to feed back and control the dose of the electron beam generated by the microwave electron gun 20.

[0070] In certain embodiments of the present invention, the electron beam energy is less than 2 MeV; the electron beam current frequency is 50 Hz; and the single pulse charge of the electron beam is 1 nC.

[0071] In certain embodiments of the present invention, a macropulse duration of the electron beam generated by the microwave electron gun 20 is set in a range of 10 nanoseconds to 100 milliseconds.

[0072] In certain embodiments of the present invention, see [Fig.4], the miniature Flash radiotherapy equipment provided by the present invention may further comprise a beam control unit 50. The beam control unit 50 is configured to control, according to the 3D data obtained by the 3D scanning unit 10 and a type of disease at the level of the target area, the microwave electron gun 20 and the beam transmission unit 30 in order to perform the scan in the target area along the target trajectory.

[0073] In certain embodiments of the present invention, the process by which the beam control unit 50 controls, according to 3D data and a disease type at the level of the target area, the microwave electron gun 20 and the beam transmission unit 30 in order to perform the scan in the target area along the target trajectory, comprises the following steps:

[0074] IF, if the disease type is a hypertrophic scar, keloid, cavernous cutaneous hemangioma, common wart, localized refractory eczema, atopic dermatitis or psoriasis, according to the 3D data, determine if the thickness of pathological tissue in the target area is less than a predefined value; if so, perform step S2; and if not, perform step S3.

[0075] For example, the predefined value may be 3 mm.

[0076] S2, command the microwave electron gun 20 to emit a beam electrons with an energy less than 1 MeV, and control the beam transmission unit 30 in order to perform the scanning in the target area along the target trajectory using the electron beam.

[0077] S3, command the microwave electron gun 20 to emit a beam of electrons with an energy greater than 1 MeV and less than 2 MeV, and command the beam transmission unit 30 in order to carry out the scanning in the target area along the target trajectory using the electron beam.

[0078] In certain embodiments of the present invention, the process by which the beam control unit 50 controls the beam transmission unit 30 in order to perform the scanning in the target area along the target trajectory using the electron beam, comprises the following steps:

[0079] Control the secondary magnets so that they move along the target trajectory, to perform the scanning of the electron beam over the target area along the target trajectory.

[0080] For example, a treatment plan can be established based on the 3D data obtained by the 3D scanning unit 10 and the type of disease to be treated. Then, a reasonable control scheme can be formulated to precisely and systematically control the energy emitted by the microwave electron gun 20 and the positions of the secondary magnets, in order to implement the treatment plan. A treatment speed of 25 s / cm² can be expected.For hypertrophic scarring, keloids, cavernous cutaneous hemangiomas, common warts, localized refractory eczema, atopic dermatitis, or psoriasis, if the thickness of the pathological tissue is less than 3 mm, the energy emitted by the microwave electron gun 20 is set to be less than 1 MeV, and a scanning treatment plan is established based on a lesion region; and if the thickness of the pathological tissue is greater than 3 mm, the energy emitted by the microwave electron gun 20 is set to be greater than 1 MeV and less than 2 MeV, and a scanning treatment plan is established based on a lesion region. It is understood that multiple treatment plans are considered for a larger area of ​​a lesion, and that the treatment plans are dynamically adjusted according to a treatment effect.

[0081] Based on the miniature Flash radiotherapy equipment provided in the preceding embodiments, the present invention further relates to a method for controlling miniature Flash radiation. See [Fig. 5]. The method for controlling miniature Flash radiation provided in the present invention may comprise the following steps:

[0082] Step S101, obtain 3D data of a target area.

[0083] The 3D data are used to determine the energy of an electron beam and to determine a target scanning trajectory in the target region using the electron beam.

[0084] Step S102, command, according to the 3D data and a type of disease at the level of the target area, a microwave electron gun and a beam transmission unit in order to carry out the scan in the target area along the target trajectory.

[0085] In certain embodiments of the present invention, the process of the aforementioned step S102 of controlling, according to 3D data and a type of disease at the level of the target area, a microwave electron gun and a beam transmission unit in order to perform the scan in the target area along the target trajectory, comprises the following steps:

[0086] IF, if the type of disease is a hypertrophic scar, a keloid, a cavernous cutaneous hemangioma, a common wart, localized refractory eczema, atopic dermatitis or psoriasis, according to the 3D data, determine if the thickness of pathological tissue in the target area is less than 3 mm; if yes, perform step S2; and if no, perform step S3.

[0087] S2, command the microwave electron gun to emit a beam electrons with an energy less than 1 MeV, and control the beam transmission unit in order to perform the scan in the target area along the target trajectory using the electron beam.

[0088] S3, command the microwave electron gun to emit a beam of electrons with an energy greater than 1 MeV and less than 2 MeV, and control the beam transmission unit in order to perform the scan in the target area along the target trajectory using the electron beam.

[0089] In certain embodiments of the present invention, the aforementioned process of S2 or S3 for controlling the beam transmission unit in order to perform the scanning in the target area along the target trajectory using the electron beam, comprises the following steps:

[0090] control the secondary magnets so that they move along the target trajectory, to achieve scanning of the electron beam over the target area along the target trajectory.

[0091] The following describes a miniature flash radiation control device provided in an embodiment of the present invention. Reference may be made to the miniature flash radiation control device described below and to the miniature flash radiation control method described above as corresponding to each other.

[0092] See [Fig. 6], the miniature flash radiation control device provided in this embodiment of the present invention may comprise:

[0093] a data acquisition unit 51, configured to obtain 3D data from a target area,

[0094] the 3D data being used to determine the energy of an electron beam and to determine a target scanning trajectory in the target region using the electron beam; and

[0095] a scanning control unit 52, configured to control, according to 3D data and a type of disease at the level of the target area, a microwave electron gun and a beam transmission unit in order to carry out the scanning in the target area along the target trajectory.

[0096] In certain embodiments of the present invention, the process by which the scanning control unit 52 controls, according to 3D data and a disease type at the level of the target area, a microwave electron gun and a beam transmission unit in order to perform the scan in the target area along the target trajectory, comprises the following steps:

[0097] If the disease type is a hypertrophic scar, keloid, cavernous cutaneous hemangioma, common wart, localized refractory eczema, atopic dermatitis or psoriasis, according to the 3D data, determine if the thickness of pathological tissue in the target area is less than 3 mm; if so, perform step S2; and if not, perform step S3.

[0098] S2, control of the microwave electron gun in order to emit a beam electrons with an energy less than 1 MeV, and control of the beam transmission unit in order to perform the scanning in the target area along the target trajectory using the electron beam.

[0099] S3, control of the microwave electron gun in order to emit a beam of electrons with an energy greater than 1 MeV and less than 2 MeV, and control the beam transmission unit in order to perform the scan in the target area along the target trajectory using the electron beam.

[0100] In certain embodiments of the present invention, the process by which the scanning control unit 52 controls the beam transmission unit in order to perform the scanning in the target area along the target trajectory using the electron beam, comprises the following steps:

[0101] control secondary magnets so that they move along the target trajectory, to achieve scanning of the electron beam over the target area along the target trajectory.

[0102] The miniature flash radiation control device provided in this embodiment of the present invention can be applied to a miniature flash radiation control device, such as a computer. Optionally, [Fig. 7] shows a schematic diagram of a hardware structure of a miniature flash radiation control device. As shown in [Fig. 7], the hardware structure of the miniature flash radiation control device may include: at least one processor 61, at least one communication interface 62, at least one memory 63, and at least one communication bus 64.

[0103] In this embodiment of the present invention, there is at least one processor 61, a communication interface 62, a memory 63 and a communication bus 64, and the processor 61, the communication interface 62 and the memory 63 communicate with each other via the communication bus 64.

[0104] The processor (61) can be a central processing unit (CPU), or an application-specific integrated circuit (ASIC), or one or more integrated circuits configured to implement embodiments of the present invention.

[0105] The memory 63 may include high-speed random access memory (RAM), and may further include non-volatile memory, or similar, such as at least one disk memory.

[0106] Memory 63 is arranged with a program, and the processor 61 can call this program stored in memory 63. The program is used to:

[0107] obtain 3D data of a target area,

[0108] the 3D data being used to determine the energy of an electron beam and to determine a target scanning trajectory in the target region using the electron beam; and

[0109] control, according to 3D data and a type of disease at the level of the target area, a microwave electron gun and a beam transmission unit in order to carry out the scan in the target area along the target trajectory.

[0110] Optionally, the detailed functions and extended functions of the program may refer to the descriptions above.

[0111] One embodiment of the present invention further relates to a storage medium. The storage medium can store a program designed to be executed by a processor. The program is used to:

[0112] obtain 3D data of a target area,

[0113] the 3D data being used to determine the energy of an electron beam and to determine a target scanning trajectory in the target region using the electron beam; and

[0114] control, according to 3D data and a type of disease at the level of the target area, a microwave electron gun and a beam transmission unit in order to carry out the scan in the target area along the target trajectory.

[0115] Optionally, the detailed functions and extended functions of the program may refer to the descriptions above.

[0116] In conclusion:

[0117] The present invention comprises a 3D scanning unit, a microwave electron gun, and a beam transmission unit. The 3D scanning unit is configured to obtain 3D data of a target area. This 3D data is used to determine the energy of an electron beam and to define a target scanning path within the target region using the electron beam. The 3D data may include information such as the thickness and location of a lesion within the target area. Depending on the lesion thickness, electron beams of different energy sizes can be established, while a scanning target can be defined based on the lesion location information, thereby determining the target scanning path. The microwave electron gun is configured to generate an electron beam current with an energy and dose tailored to the 3D data.The beam transmission unit is configured to transmit the electron beam generated by the microwave electron gun and allow the electron beam to scan the target area along the target trajectory. Since the energy, dose, and target trajectory of the electron beam are all determined based on 3D data, the entire electron beam scanning process can be highly automated, enabling the achievement of Flash radiotherapy objectives for disease foci such as superficial hyperplasia of the human body, skin cancer, and hemangioma.

[0118] Finally, it should be noted that relational terms such as first and second here are used only to distinguish one entity or operation from another entity or operation without necessarily requiring or implying an actual relationship or order between those entities or operations. Furthermore, the terms "include," "comprising," or any variant thereof, are intended to denote non-exclusive inclusion, so that a process, method, article, or device that includes a list of elements does not include only those elements, but may include other elements not explicitly listed or inherent in that process, method, article, or device. Without further limitation, an element defined by the expression " including a... » does not exclude the presence of other identical elements in the process, procedure, article or device which includes the element.

[0119] The embodiments of this description are all described progressively, and each embodiment focuses on the differences from the other embodiments. The embodiments can be combined as needed, and reference can be made to parts that are identical and similar to one another.

[0120] The above description of the embodiments described enables a person skilled in the art to carry out or use the present invention. Modifications to these embodiments will be obvious to a person skilled in the art, and the general principle defined in this document can be implemented in other embodiments without departing from the scope of the present invention. Thus, instead of being limited to the embodiments described herein, the present invention will be applied in the broadest possible scope compatible with the principles and new features described herein.

Claims

Demands

1. Miniature Flash radiotherapy equipment, characterized in that it comprises: a 3D scanning unit (10) which is used to obtain 3D data of a target area, said 3D data being used to determine the energy of an electron beam and to determine a target scanning trajectory in the target region using the electron beam; a microwave electron gun (20), which is used to generate an electron beam current having an energy and dose adapted to the 3D data, the energy of said electron beam being less than 2 MeV;a beam transmission unit (30), which is used to transmit the electron beam generated by the microwave electron gun (20) and to enable said electron beam to perform the scan in the target area along the target trajectory, said beam transmission unit (30) comprising a vacuum beam pipeline (31) and two sets of secondary magnets (32), said vacuum beam pipeline (31) having a diameter of 10 cm and being used to transmit the electron beam, and said secondary magnets (32) being used to control a scanning position of said electron beam;and a beam current intensity measurement unit (40) arranged at a rear portion of said beam transmission unit (30), which is used to determine a dose of the electron beam passing through the vacuum beam pipeline (31), said dose being used to feed back and control the dose of the electron beam generated by said microwave electron gun (20).

2. Equipment according to claim 1, characterized in that, a separation film is arranged at one end of said vacuum beam pipeline (31); said separation film is used to separate a vacuum environment inside the vacuum beam pipeline (31) from an air environment outside the vacuum beam pipeline (31).

3. Equipment according to claim 2, characterized in that said separation film is a titanium film, or a beryllium film of a thickness of 100 pm.

4. Equipment according to claim 1, characterized in that the frequency of said electron beam current is 50 Hz, and the single pulse charge for said electron beam current is 1 nC.

5. Equipment according to claim 1, characterized in that it further comprises: a beam control unit (50), which is used to control, according to 3D data and a type of disease at the level of the target area, said microwave electron gun (20) and said beam transmission unit (30) in order to carry out the scanning in the target area along the target trajectory.

6. Equipment according to any one of claims 1 to 5, characterized in that, a macro-pulse duration of said electron beam generated by the microwave electron gun (20) is set in a range of 10 nanoseconds to 100 milliseconds.