ABCB5 stem cell processing

JP2024537393A5Pending Publication Date: 2025-10-22RHEACELL GMBH & CO KG
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Patent Information

Application Number
JP2024522479
Authority / Receiving Office
JP · JP
Patent Type
Applications
Current Assignee / Owner
Filing Date
2022-10-14
Publication Date
2025-10-22

AI Technical Summary

Technical Problem

There is a lack of effective methods for packaging and storing ABCB5+ stem cells in precise therapeutic amounts for single-use applications, which limits their therapeutic use.

Method used

A method for isolating and packaging ABCB5+ stem cells in unit-of-use containers, ensuring a consistent concentration and volume, using closed system cold storage vials that can withstand extreme temperatures, allowing for cryopreservation and subsequent therapeutic use.

Benefits of technology

Enables reliable storage and delivery of ABCB5+ stem cells in therapeutic doses, facilitating their use in various medical treatments by maintaining cell viability and functionality.

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Abstract

Provided is a population of therapeutic ABCB5+ stem cells presented in a unit-of-use cryogenic storage vial. Also provided are methods of making and using the therapeutic cells. The closed system cryogenic storage vial may include a fill tube and an air vent connected to the cell container.
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