Novel anti-IL-36R antibody
JP2024541982A5Pending Publication Date: 2025-11-04インマージーン プライベート リミテッド
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Patent Information
- Application Number
- JP2024525339
- Authority / Receiving Office
- JP · JP
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2022-09-13
- Filing Date
- 2022-10-27
- Publication Date
- 2025-11-04
AI Technical Summary
Technical Problem
There is a high unmet medical need for novel anti-IL-36R antibodies to address IL-36R-related skin diseases.
Method used
Development of antibodies or antigen-binding fragments that specifically bind to human IL-36R, comprising specific heavy and light chain complementarity determining regions (CDRs) with defined amino acid sequences, capable of inhibiting IL-36R signaling and modulating inflammatory responses.
Benefits of technology
The antibodies effectively inhibit IL-36R agonist-induced cytokine release, providing therapeutic potential for IL-36R-related diseases such as psoriasis and other inflammatory conditions.
✦ Generated by Eureka AI based on patent content.
Abstract
The present disclosure provides anti-IL-36R antibodies or antigen-binding fragments thereof, isolated polynucleotides encoding them, pharmaceutical compositions comprising them, and uses thereof.
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