Anal narrowing treatment method

Abstract

To provide a treatment method for narrowing the opening of the anus while allowing bowel movement.SOLUTION: The present invention comprises the following treatments: (a) performing alcohol disinfection on the anus part, and then applying 2% of lidocaine hydrochloride jelly (xylocaine jelly); (b) injecting lidocaine 1% liquid into the skin, mucous membrane part, and muscle part in the vicinity of the surface of the anus and the rectum connected to the anus; (c) injecting hyaluronic acid into a plurality of locations of the skin, mucous membrane part, and muscle part near the surface of the anus and rectum; and (d) performing alcohol disinfection on the locations where the hyaluronic acid was injected, and affixing a gauze.SELECTED DRAWING: None

Description

[Technical field]

[0001] The present invention relates to a method of treatment for improving a condition in which the anus becomes loose or remains in a dilated state, resulting in stool leakage and other problems, and for narrowing the anal opening while allowing bowel movements. [Background technology]

[0002] For example, the anus can become loose or remain dilated due to everyday constipation, hemorrhoids, aging, congenital factors, sexual intercourse, etc. If this is left untreated, loose stools can lead to incontinence (leaking stool), forcing the wearer to wear diapers or sheets, or causing pain and discomfort in the anus, interfering with daily life. For LGBT people, it can also make sexual intercourse less enjoyable.

[0003] Treatment for mild fecal incontinence caused by loosening of the anus can sometimes be achieved by improving daily life by adjusting diet and fluid intake, and by muscle exercises focusing on the anus. However, when the anal dilation does not improve to a normal state, the treatment that has been used up until now has mainly been a surgical procedure in which the anus and a portion of the lower rectum connected to the anus are removed, and the removed area is then sewn up to narrow the anus. Summary of the Invention [Problem to be solved by the invention]

[0004] The large intestine mainly absorbs water and does little digestive function. The rectum is the part of the large intestine that connects to the anus and is made up of three layers of membranes: the mucosa, the muscular layer, and the serous membrane. However, the lower rectum and the anus are outside the abdominal cavity and do not have a serous membrane.

[0005] The rectum is lined with simple columnar epithelium, and the anal surface is lined with stratified squamous epithelium, which is resistant to mechanical stimuli. The internal circular muscle is developed just above the anus, forming the internal anal sphincter, and in addition to the sphincter made of smooth muscle, there is also the external anal sphincter made of striated muscle.

[0006] The anus is opened and closed reflexively by the sphincter muscle, which is made up of smooth muscle, while the external anal sphincter muscle, which is made up of striated muscle, opens and closes the anus in accordance with the will.

[0007] For this reason, conventional surgical procedures using a scalpel (including an electric scalpel) to remove the anus and the lower rectum connected to the anus cut away not only the mucosa and muscle layer, but also the sphincter and striated muscle components. Even if the excised area is stitched up after the procedure, the patient must wait for the natural healing powers of the operated area to recover, and during that time the patient is unable to defecate.

[0008] For this reason, it takes a long time, about two weeks to a month, to make a full recovery, and if the patient defecates before the wound is fully healed, or if loose stool soaks into the surgical site, the wound may worsen and never recover. In this case, feces contains a lot of E. coli, so if E. coli infects the wound at the surgical site, it will cause suppuration, and it is often necessary to take time to treat the suppuration of the wound by administering antibiotics, etc. [Means for solving the problem]

[0009] Therefore, in order to solve the various problems described above, the present application provides a treatment method for narrowing the anal opening to treat anal dilation and fecal incontinence, which comprises the following procedures: (a) applying 2% lidocaine hydrochloride jelly (generic name: xylocaine jelly) to the anal area after disinfecting it with alcohol; (b) injecting 1% lidocaine solution into the skin, mucous membrane, and muscle near the surface of the anus and the rectum connected thereto; (c) injecting hyaluronic acid into multiple sites of the skin, mucous membrane, and muscle near the surface of the anus and rectum; and (d) disinfecting the areas where the hyaluronic acid was injected with alcohol and covering them with gauze.

[0010] Here, instead of or together with the treatment (b), general anesthesia using intravenous anesthesia or nitrous oxide anesthesia is administered.

[0011] Depending on the symptoms, the injection of hyaluronic acid in the treatment (b) may be performed together with the injection of an exosome complex or a substance containing stem cells. Effect of the Invention

[0012] Conventional surgical procedures for removing the anus and rectum mean that patients are unable to naturally defecate from the anus for at least two weeks after the surgery, and thereafter, they must wait for the patient's natural healing powers to recover.

[0013] On the other hand, in this treatment method, the anus closes immediately after the procedure, and there is a low risk of the site becoming infected and suppurating due to mold bacteria such as E. coli. In addition, the wound from the needle used to inject hyaluronic acid closes in about half a day, so defecation becomes possible the day after or the day after the procedure.

[0014] In addition, hyaluronic acid is not only safe, but also an essential body tissue component, because it is originally distributed widely throughout the body, including human skin and joints, and the amount of injection can be determined according to symptoms, so the injection site and injection amount of hyaluronic acid liquid can be determined according to the anal expansion state, and the degree of anal closure after treatment can be adjusted. This treatment method can also correct the anal distortion to a proper or desirable shape, and improve or adjust the contact state between the rectum and the prostate. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

[0015] The present invention provides a method for treating a dilated anus and narrowing the anal opening to treat fecal incontinence, in which the anal area is disinfected with alcohol prior to the procedure.

[0016] Next, 2% lidocaine hydrochloride jelly (xylocaine jelly) is applied, and 1% lidocaine solution is injected. In this case, depending on the symptoms of the affected area, general anesthesia using intravenous anesthesia or nitrous oxide anesthesia may be administered.

[0017] Hyaluronic acid is then injected into multiple locations in the skin, mucous membrane, and muscle near the surface of the affected anus and rectum, depending on the severity of the anal opening.

[0018] Here, we will briefly explain hyaluronic acid. Hyaluronic acid is widely distributed in the bodies of humans and vertebrates, and is found mainly in the skin, joints, and vitreous body of the eye. In humans, half of the hyaluronic acid is found in the skin, and it is also found in the extracellular matrix of the body widely, such as in the brain, and protects cell tissues.

[0019] As is widely known, hyaluronic acid has a physiological function of preventing dryness in the skin by its ability to retain water, and protecting cell tissue. It is also known that it exerts viscosity by retaining water, reducing wear on joints.

[0020] Hyaluronic acid is a type of linear glycosaminoglycan (mucopolysaccharide), and as mentioned above, it has high water retention and becomes viscous due to water retention. It is distributed widely in the body and plays an important role in the skin, cartilage, and eyeballs.

[0021] The molecular weight of hyaluronic acid can reach 2 million, but the minimum is 411. The higher the molecular weight of hyaluronic acid, the less it is absorbed by the body. For this reason, in this treatment method, the amount of low molecular weight hyaluronic acid and high molecular weight hyaluronic acid is adjusted according to the symptoms. In addition, if necessary, it is possible to inject about 1cc or more of a filler agent that is not permanently absorbed by the body.

[0022] Hyaluronic acid is a substance that is safe for the human body, and so it is generally known for its use in beauty treatments, but it has also been approved for use in medical procedures both in Japan and overseas.

[0023] In this treatment, hyaluronic acid is injected together with exosome complex or stem cell-containing substance according to the degree of anal dilatation. If too much hyaluronic acid is injected or the patient feels some discomfort after treatment, hyaluronic acid can be dissolved by injecting hyaluronic acid dissolving solution.

[0024] In addition, in this treatment method, the injection of hyaluronic acid is accompanied by the injection of a substance containing an exosome complex or stem cells.

[0025] Here, the exosome complex is a multiprotein complex that exists in the nuclei of eukaryotes and archaea and degrades various RNAs. The center of the exosome is composed of six proteins accompanied by other proteins, and exhibits exoribonuclease activity to degrade RNA from its ends. In the case of eukaryotic cells, it also exhibits endoribonuclease activity and can cleave the middle of the RNA chain. This leads to the production of autoantibodies that target the constituent proteins of the exosome, which promotes regeneration of the treatment site.

[0026] Finally, this treatment ends with disinfecting the area where the hyaluronic acid was injected with alcohol and then covering it with gauze.

[0027] As mentioned above, in conventional surgical procedures for removing the anus and rectum, patients were unable to defecate for one month after the procedure and had to wait for recovery through natural healing powers. However, with this treatment method, the anus closes immediately after the procedure and the wound made by the needle used to inject hyaluronic acid closes in about half a day, so patients are able to defecate the next day or the day after.

[0028] In addition, hyaluronic acid is a safe substance that is widely distributed throughout the body, including in the skin and joints, so the injection site and amount of hyaluronic acid liquid can be determined arbitrarily depending on the state of anal expansion, making it possible to adjust the degree of closure of the anus after treatment.

Claims

1. 1. A method of treating a dilated anus and narrowing the anal opening to treat fecal incontinence, comprising: (a) After disinfecting the anal area with alcohol, apply 2% lidocaine hydrochloride jelly (xylocaine jelly); (b) injecting 1% lidocaine into the skin, mucous membrane, and muscle adjacent to the surface of the anus and rectum; (c) injecting hyaluronic acid into multiple sites in the skin, mucous membranes, and muscles adjacent to the surface of the anus and rectum; (d) Disinfect the area where the hyaluronic acid was injected with alcohol and cover it with gauze. Anal stenosis treatment consists of various procedures.

2. 2. The method for treating anal stenosis according to claim 1, wherein general anesthesia using intravenous anesthesia or nitrous oxide anesthesia is administered instead of or together with the treatment (b).

3. The method for treating anal stenosis according to claim 1 or 2, wherein the injection site and injection amount of the hyaluronic acid liquid are determined according to the state of anal dilation.

4. The method for treating anal stenosis according to claim 3, wherein the injection of hyaluronic acid in the treatment (b) is performed together with the injection of an exosome complex or a substance containing stem cells.