Organism insertion device

Abstract

To provide an organism insertion device that includes an insertion body having a boundary due to presence or absence of a coating layer in an insertion extraction direction, and can suppress the coating layer from peeling off from a position of the boundary in the insertion body.SOLUTION: An organism insertion device includes an insertion body capable of being inserted into an organism, and a protector for covering the external surface of the insertion body. The insertion body has a base body, and a coating layer covering the outside of the base body. The insertion body has a light transmission part where the base body is not covered with the coating layer, and a light transmission restriction part where the base body is covered with the coating layer. The light transmission part and the light transmission restriction part are adjacent to each other in an insertion extraction direction of the insertion body, and the protector covers the external surface of the insertion body so as to stride a boundary between the light transmission part and the light transmission restriction part in the insertion extraction direction of the insertion body.SELECTED DRAWING: Figure 3

Description

[Technical field]

[0001] The present disclosure relates to bioinsertion devices. [Background technology]

[0002] There is known a phototherapy device used to irradiate abnormal tissue with therapeutic light. Patent Document 1 describes this type of phototherapy device. The phototherapy device described in Patent Document 1 includes a balloon having a defined treatment window that delivers irradiation to a defined area. The treatment window of the balloon in Patent Document 1 is defined by coating the periphery with a reflective material. [Prior art documents] [Patent documents]

[0003] [Patent Document 1] JP 2005-46640 A Summary of the Invention [Problem to be solved by the invention]

[0004] The balloon in the phototherapy device as a biological insertion device described in Patent Document 1 has a portion where the base body is covered with a coating as a covering layer, and a treatment window where the base body is not covered with a coating as a covering layer, and a step may be formed at the boundary between them due to the presence or absence of a coating. In a balloon as an insert that can be inserted into a living body, if there is a boundary that forms the above-mentioned step in the insertion / removal direction, the above-mentioned step may get caught on biological tissue or a medical instrument used together with the biological insertion device when the insert is inserted or removed, and the coating as a covering layer may peel off from the base body.

[0005] The present disclosure aims to provide a biological insertion device having an insert body with a boundary between the presence and absence of a coating layer in the insertion / removal direction, which can prevent the coating layer from peeling off at the position of the boundary of the insert body. [Means for solving the problem]

[0006] The biological insertion device according to the first aspect of the present disclosure includes: (1) An insert that can be inserted into a living body; A protective body covering an outer surface of the insert, The insert comprises: A base body; A coating layer that covers the outside of the base body, The insert comprises: a light transmitting portion where the base body is not covered with the covering layer; a light transmission limiting portion in which the base body is covered with the covering layer; The light transmitting portion and the light transmission limiting portion are adjacent to each other in the insertion / removal direction of the insert body, The protector is a living body insertion device that covers the outer surface of the insertion body so as to straddle the boundary between the light transmitting portion and the light transmission limiting portion in the insertion / removal direction.

[0007] As one embodiment of the present disclosure, the biological insertion device includes: (2) The insert contains or is capable of containing a light irradiation unit therein, The living body insertion device according to (1) above, wherein the transmittance of the covering layer to the light from the light irradiating unit is lower than the transmittance of the base body to the light from the light irradiating unit.

[0008] As one embodiment of the present disclosure, the biological insertion device includes: (3) The insertion body is the biological insertion device according to (1) or (2) above, which is an expandable body capable of expansion and contraction.

[0009] As one embodiment of the present disclosure, the biological insertion device includes: (4) A long shaft portion extends through the inside of the expansion body, The expansion body is an expandable body portion capable of expanding and contracting; a distal fixing portion connected to a distal side of the expansion body portion and fixed to the shaft portion; a proximal fixing portion connected to a proximal side of the expansion body portion and fixed to the shaft portion, the boundary is located on the expanded body portion and on at least one of the distal fixation portion and the proximal fixation portion; The protective body is a biological insertion device described in (3) above, which covers the outer surface of the expansion body so as to span the boundary located at at least one of the distal fixation portion and the proximal fixation portion of the expansion body.

[0010] As one embodiment of the present disclosure, the biological insertion device includes: (5) The bioinsertion device according to (1) or (2) above, wherein the insertion body is a tubular body.

[0011] As one embodiment of the present disclosure, the biological insertion device includes: (6) The bioinsertion device according to any one of (1) to (5) above, wherein the protective body contains a metal having X-ray contrast properties.

[0012] As one embodiment of the present disclosure, the biological insertion device includes: (7) The biological insertion device according to any one of (1) to (5) above, wherein the protector is made of resin. Effect of the Invention

[0013] According to the present disclosure, it is possible to provide a biological insertion device having an insert body with a boundary between the presence and absence of a coating layer in the insertion / removal direction, which is capable of preventing the coating layer from peeling off at the position of the boundary of the insert body. [Brief description of the drawings]

[0014] [Figure 1] FIG. 1 is a diagram showing an example of an endoscope system including a light irradiation device as one embodiment of a living body insertion device according to the present disclosure. [Diagram 2] FIG. 2 is a diagram showing the light irradiation device shown in FIG. [Diagram 3] FIG. 3 is an enlarged view of the vicinity of the expandable body in FIG. 2. [Figure 4] 3 is a cross-sectional view of the light irradiation device taken along line II in FIG. 2. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

[0015] Hereinafter, an embodiment of a biological insertion device according to the present disclosure will be illustrated and described with reference to the drawings. In each drawing, the same components are given the same reference numerals.

[0016] FIG. 1 is a diagram showing an example of an endoscope system 100 including a light irradiation device 1 as an embodiment of a living body insertion device according to the present disclosure. The endoscope system 100 shown in FIG. 1 includes an endoscope apparatus 101, a control device 102 connected to the endoscope apparatus 101, a display unit 103 such as a monitor connected to the control device 102, a light source apparatus 104, and a light irradiation device 1. The endoscope apparatus 101 is partitioned with a treatment tool channel through which the light irradiation device 1 can be inserted as a treatment tool. As shown in FIG. 1, the light irradiation device 1 is inserted into the treatment tool channel of the endoscope apparatus 101 and delivered to a lesion in the lumen. The control device 102 includes a light source unit 102a that supplies illumination light to the endoscope apparatus 101, and a processor unit 102b that performs various image processing on an image signal from the endoscope apparatus 101 to convert it into a video signal. The control device 102 may also include an input unit such as a keyboard. The display unit 103 is capable of displaying an image captured by the endoscope device 101 based on a video signal generated by the processor unit 102 b of the control device 102 .

[0017] The light irradiation device 1 can be used for, for example, a photodynamic therapy (PDT) treatment or a photoimmunotherapy (PIT) treatment. The light irradiation device 1 can be inserted into a cavity such as a biological lumen. The light irradiation device 1 may be used together with an endoscope device 101 as shown in FIG. 1. However, the light irradiation device 1 does not have to be used together with the endoscope device 101. In addition, the cavity into which the light irradiation device 1 can be inserted is not particularly limited. As shown in FIG. 1, the light irradiation device 1 may be used for treating cancer in a luminal organ through a treatment tool channel of an endoscope device 101 inserted into a luminal organ such as the digestive tract (esophagus, stomach, small intestine, large intestine, etc.), the urinary tract, or a blood vessel. In this embodiment, the light irradiation device 1 is used for, for example, photoimmunotherapy taught in Japanese Patent No. 6127045, in which a drug adsorbed on a target cell is irradiated with light to destroy the target cell. The target cell is a tumor cell such as a cancer cell or a cell of a precancerous lesion. In this treatment method, a photosensitive substance that adsorbs an antibody that specifically binds only to a specific antigen on the surface of a tumor cell and a photosensitive substance that pairs with the antibody is used as a drug. The antibody is not particularly limited, but examples include panitumumab, trastuzumab, HuJ591, pertuzumab, lapatinib, palbociclib, and olaparib. The photosensitive substance is, for example, but not limited to, a hydrophilic phthalocyanine (IR700) that reacts to near-infrared rays with a wavelength of about 700 nm. When IR700 is exposed to near-infrared rays with a wavelength of about 660 to 740 nm, the ligand of the functional group that ensures water solubility is broken, and a structural change occurs from water solubility to hydrophobicity. This structural change pulls out membrane proteins, opening holes in the cell membrane and allowing water to enter the cell, thereby rupturing and destroying the tumor cells. In addition, IR700 is excited by receiving near-infrared rays and emits fluorescence with a wavelength different from the excitation wavelength. For example, when IR700 is excited by near-infrared light with a wavelength of about 690 nm, it emits fluorescence with a wavelength of about 700 nm. IR700 undergoes a structural change while emitting fluorescence in response to light, and when it destroys tumor cells and fulfills its role as a drug, it no longer emits fluorescence.

[0018] In the present embodiment, a light irradiation device 1 will be described as an example of an embodiment of a living body insertion device according to the present disclosure, but the living body insertion device according to the present disclosure is not limited to a light irradiation device. The living body insertion device according to the present disclosure may be a living body insertion device used for a treatment other than a light treatment, such as a balloon catheter or other catheter that is not used for a light treatment.

[0019] FIG. 2 is a diagram showing the light irradiation device 1. More specifically, FIG. 2 is a cross-sectional view of the light irradiation device 1 in a cross section parallel to the central axis direction parallel to the central axis O1, passing through the central axis O1 of the insertion body part 2. FIG. 3 is an enlarged view showing the vicinity of the expansion body 30 in FIG. 2. As shown in FIG. 2 and FIG. 3, the light irradiation device 1 includes a long insertion body part 2 and a protective body 300. The insertion body part 2 can be inserted into and removed from a living body along the central axis O1 of the insertion body part 2. The insertion body part 2 includes the expansion body 30 as the insertion body 301. The protective body 300 covers the outer surface of the expansion body 30 as the insertion body 301. As described above, the insertion body 301 of this embodiment can be inserted into and removed from a living body along the central axis O1 of the insertion body part 2. That is, the insertion and removal direction A of the insertion body 301 of this embodiment is the central axis direction along the central axis O1 of the insertion body part 2. Hereinafter, for convenience of explanation, the direction of inserting the insert 301 into the living body in the insertion / removal direction A is described as "insertion direction A1". The insertion direction A1 in this embodiment is a direction from the proximal side to the distal side in the central axis direction of the insertion body 2. In addition, for convenience of explanation, the direction of removing the insert 301 from the living body to the outside of the living body in the insertion / removal direction A is described as "removal direction A2". The removal direction A2 in this embodiment is a direction from the distal side to the proximal side in the central axis direction of the insertion body 2. Furthermore, the direction around the axis along the insertion / removal direction A is described as "circumferential direction B". The circumferential direction B in this embodiment is a direction around the central axis O1 of the insertion body 2. Furthermore, the radial direction of a virtual circle centered on an axis along the insertion / removal direction A is described as "radial direction C". The radial direction C in this embodiment is a radial direction of a virtual circle centered on the central axis O1 of the insertion body 2.

[0020] As shown in FIG. 3, the extension body 30 as the insert body 301 includes a base body 90a and a covering layer 90b covering the outside of the base body 90a. The extension body 30 as the insert body 301 also includes a light transmitting section 2a and a light transmission limiting section 2b. The light transmitting section 2a is a portion of the base body 90a that is not covered by the covering layer 90b. The light transmission limiting section 2b is a portion of the base body 90a that is covered by the covering layer 90b. The transmittance of the light transmitting limiting section 2b for light from the light irradiating section 200 (see FIG. 2, etc.) described later is smaller than the transmittance of the light transmitting section 2a for light from the light irradiating section 200. The base body 90a is made of a light transmitting material that can transmit light from the light irradiating section 200 (see FIG. 2, etc.) described later. The covering layer 90b may be a coating material that covers the outside of the base body 90a and reflects or blocks at least a part of the light that passes through the base body 90a. Such a covering layer 90b may be made of a light transmission limiting material having a transmittance of light from a light irradiating unit 200 (see FIG. 2, etc.) described later lower than that of the base body 90a. The outer surfaces of the light transmitting unit 2a and the light transmission limiting unit 2b may be covered with a lubricating coating material made of a transparent material that can transmit light from the light irradiating unit 200 (see FIG. 2, etc.) described later.

[0021] As shown in Fig. 3, the light transmitting portion 2a and the light transmission limiting portion 2b are adjacent to each other in the insertion / removal direction A. More specifically, the insertion body 301 of this embodiment is a balloon serving as the expansion body 30, and can be inserted into a living body. The balloon serving as the expansion body 30 of this embodiment has an elongated shape along the insertion / removal direction A. In other words, as shown in Fig. 3, the light transmitting portion 2a and the light transmission limiting portion 2b of the expansion body 30 serving as the insertion body 301 of this embodiment are adjacent to each other in the longitudinal direction of the expansion body 30 serving as the insertion body 301.

[0022] 3, the protector 300 covers the outer surface of the insertion body 301 so as to straddle the boundary between the light transmitting portion 2a and the light transmission limiting portion 2b in the insertion / removal direction A. More specifically, the protector 300 of this embodiment covers the outer surface of the expansion body 30 so as to straddle the boundary BL1 between the light transmitting portion 2a and the light transmission limiting portion 2b in the insertion / removal direction A, which is located at a distal fixing portion 36 described later of the expansion body 30 as the insertion body 301. In addition, the protector 300 of this embodiment covers the outer surface of the expansion body 30 so as to straddle the boundary BL2 between the light transmitting portion 2a and the light transmission limiting portion 2b in the insertion / removal direction A, which is located at a proximal fixing portion 37 described later of the expansion body 30.

[0023] By providing such a protective body 300, the step due to the presence or absence of the covering layer 90b formed at the boundaries BL1, BL2 between the light transmitting portion 2a and the light transmission limiting portion 2b in the insertion / removal direction A of the insert 301 can be covered by the protective body 300. Therefore, peeling of the covering layer 90b from the positions of the boundaries BL1, BL2 in the insert 301 can be suppressed.

[0024] As described above, the protector 300 of this embodiment is disposed so as to straddle the boundaries BL1, BL2 between the light transmitting portion 2a and the light transmission limiting portion 2b formed in the expansion body 30 as the insert 301, but is not limited to this configuration. The protector 300 may be disposed so as to straddle the boundaries between the light transmitting portion 2a and the light transmission limiting portion 2b formed in another insert 301 (e.g., a tubular body) different from the expansion body 30. Hereinafter, in this embodiment, the protector 300 disposed so as to straddle the boundaries BL1, BL2 between the light transmitting portion 2a and the light transmission limiting portion 2b in the insertion / removal direction A formed in the expansion body 30 as the insert 301 will be illustrated.

[0025] First, the light illuminating device 1 of this embodiment will be described with reference to Fig. 2 to Fig. 4. Fig. 4 is a cross-sectional view of the light illuminating device 1 taken along line II in Fig. 2.

[0026] As shown in Figs. 2 to 4, the light irradiation device 1 of this embodiment includes an insertion section 1a that can be inserted into a living body, and a handheld operation section 1b that is located proximal to the insertion section 1a and is not inserted into the living body. The insertion section 1a of this embodiment includes an insertion main body section 2 and a protection body 300. The insertion main body section 2 of this embodiment includes a long shaft section 3, an expansion body 30, and a distal protection section 80. The shaft section 3 of this embodiment includes a first tubular body 10 and a second tubular body 20. The handheld operation section 1b of this embodiment includes a hub 40, an operation section 50, and a fixing section 60.

[0027] First, an example of a method of using the light irradiation device 1 will be described. Prior to treatment by the light irradiation device 1, a photosensitive substance is administered into the body. The method of administering the photosensitive substance into the body is not particularly limited as long as the photosensitive substance can reach tumor cells, but for example, it is intravascular administration, and in this embodiment, it is intravenous administration. After about 12 to 36 hours have passed since the intravenous administration, a light irradiation treatment is performed by the light irradiation device 1 of this embodiment. A light irradiator 201 described later is inserted into the first tubular body 10 of the light irradiation device 1 in the insertion direction A1, and the light irradiation section 200 provided on the distal end side of the light irradiator 201 is placed at a predetermined position in the first tubular body 10. The hub 40 includes a hub main body 41 and a connection part 42. The connection part 42 of the hub 40 holds the light irradiator 201 so as to surround the light irradiator 201. The light irradiator 201 may be fixed to the light irradiation device 1 by rotating and screwing the connection part 42 with respect to the hub body 41 in a state where the light irradiator 201 is inserted into the first tubular body 10 of the light irradiation device 1. Conversely, the light irradiator 201 can be removed from the first tubular body 10 of the light irradiation device 1 by releasing the screwing between the hub body 41 and the connection part 42. In this embodiment, the light irradiator 201 has a light irradiation part 200 provided on the distal end side, and a light transmission member 202 such as an optical fiber connected to the light irradiation part 200 and extending to the proximal end side. The proximal end of the light transmission member 202 is connected to the light source device 104. For example, the light irradiator 201 may be composed of a side light emitting optical fiber that can irradiate light radially outward all around at the distal end. In addition, the extension body 30 of the light irradiation device 1 is in a contracted state in this state.

[0028] Next, the light irradiation device 1 and the light irradiating body 201 fixed to the light irradiation device 1 are inserted into the living body through the treatment tool channel of the endoscope apparatus 101 (see FIG. 1). At this time, the position of a light transmitting window portion 31 (described later) in the expansion body 30 is aligned with the position to be irradiated, such as a lesion formed in the living tissue that defines the cavity, in the insertion / removal direction A and the circumferential direction B. The alignment in the insertion / removal direction A is performed by moving the light irradiation device 1 in the insertion direction A1 or the removal direction A2. The alignment in the circumferential direction B is performed by rotating the light irradiation device 1 in the circumferential direction B.

[0029] Next, the expansion body 30 is expanded from the contracted state. The expansion body 30 may be expanded in two stages, for example, an adjustment expansion state in which light irradiation to the irradiation target is not performed, and a treatment expansion state in which the internal pressure is higher than that of the adjustment expansion state and light irradiation to the irradiation target is performed. The adjustment expansion state of the expansion body 30 may be used for fine adjustment of the alignment between the position of a light-transmitting window portion 31 (described later) in the expansion body 30 and the position of the irradiation target in the insertion / removal direction A and the circumferential direction B.

[0030] By putting the expandable body 30 in a therapeutic expanded state (hereinafter simply referred to as the "expanded state"), a light-transmitting window portion 31 of the expandable body 30, which will be described later, is brought into close contact with the irradiation target. In this state, the irradiation target can be irradiated with light that is emitted from the light irradiating unit 200 and transmits through the light-transmitting window portion 31 outward in the radial direction C. The irradiation time for the irradiation target is not particularly limited, but may be, for example, several minutes to several tens of minutes.

[0031] After the treatment is completed, the expansion body 30 is contracted, and the light irradiation device 1, together with the light irradiator 201, is removed from the living body through the treatment tool channel of the endoscope apparatus 101 (see FIG. 1).

[0032] As shown in FIG. 2 to FIG. 4, the shaft portion 3 extends so as to pass through the inside of the expansion body 30. As described above, the shaft portion 3 of this embodiment includes the first tubular body 10 and the second tubular body 20. The first tubular body 10 defines an accommodation space 10a therein that accommodates or can accommodate the light irradiation portion 200. More specifically, the first tubular body 10 of this embodiment can accommodate a light emitting portion as the light irradiation portion 200 included in a light irradiator 201 separate from the light irradiation device 1. The light irradiator 201 may include the light irradiation portion 200 that emits light toward the outside in the radial direction C, and a light transmission member 202 such as an optical fiber that transmits light from the light source device 104 (see FIG. 1) to the light irradiation portion 200. In the light irradiator 201 of this embodiment, the light irradiation portion 200 is attached to the distal end of the light transmission member 202. The light irradiation section 200 of the light irradiator 201 can be inserted into the accommodation space 10a in the insertion direction A1 from the proximal opening 10a1 of the accommodation space 10a located at the proximal end of the first tubular body 10. More specifically, the light irradiator 201 is inserted into the accommodation space 10a in the insertion direction A1 to a set position where the light irradiation section 200 overlaps with the light transmission window section 31 of the expansion body 30 described later in the insertion / removal direction A. As shown in Figs. 2 and 3, the distal side of the accommodation space 10a in this embodiment is closed. In the light irradiation device 1 and the light irradiator 201 of this embodiment, the above-mentioned set position is realized by abutting the distal end of the light irradiator 201 against the closing wall 15b on the distal side of the accommodation space 10a of the first tubular body 10.

[0033] Here, in the light irradiation device 1 of this embodiment, the central axis O1 of the insertion main body 2 described above coincides with the central axis of the first tubular body 10. Therefore, the insertion / removal direction A of this embodiment is the same as the direction along the central axis of the first tubular body 10. Moreover, the circumferential direction B of this embodiment is the same as the direction around the central axis of the first tubular body 10. Furthermore, the radial direction C of this embodiment is the same as the radial direction of a virtual circle centered on the central axis of the first tubular body 10.

[0034] The light irradiation section 200 may be provided in the accommodation space 10a of the first tubular body 10. In other words, the light irradiation device 1 may be configured to include the light irradiation section 200 accommodated in the accommodation space 10a.

[0035] The intensity and wavelength of the light emitted from the light irradiating unit 200 may be appropriately selected depending on, for example, the type of drug used in combination, the condition and position of the lesion, etc. The light emitted from the light irradiating unit 200 may be, for example, visible light such as near-infrared light.

[0036] The first tubular body 10 is configured to be able to transmit light emitted from the light irradiating unit 200 housed in the housing space 10a in the radial direction C. The first tubular body 10 may be formed, for example, from a transparent resin material as a light transmitting material that can transmit the light emitted from the light irradiating unit 200. In other words, the first tubular body 10 may be configured to be able to transmit the light emitted from the light irradiating unit 200 outward in the radial direction C over the entire area in the circumferential direction B.

[0037] The resin material used to form the first tubular body 10 is not particularly limited, and examples thereof include polyolefins such as polyethylene, polypropylene, and ethylene-propylene copolymers; ethylene-vinyl acetate copolymers (EVA); polyvinyl chloride; polyvinylidene chloride; polystyrene; polyamide; polyamide elastomers; polyimide; polyamideimide; polycarbonate; poly-(4-methylpentene-1); ionomers; acrylic resins; polymethyl methacrylate; acrylonitrile-butadiene-styrene copolymers (ABS resins); acrylonitrile-styrene copolymers (AS resins); butadiene-styrene copolymers. Examples of the resin materials include: polyesters such as polyethylene terephthalate (PET), polybutylene terephthalate (PBT), and polycyclohexane terephthalate (PCT); polyether; polyether ketone (PEK); polyether ether ketone (PEEK); polyetherimide; polyacetal (POM); polyphenylene oxide; modified polyphenylene oxide; polysulfone; polyether sulfone; polyphenylene sulfide; polyarylate; aromatic polyester (liquid crystal polymer); polytetrafluoroethylene, polyvinylidene fluoride, and other fluorine-based resins. Also, a blend containing one or more of these may be used.

[0038] Furthermore, the first tubular body 10 may be configured to have a transmission window that allows the light emitted from the light emitting section 200 to pass outward in the radial direction C only in a part of the circumferential direction B.

[0039] The expansion body 30 covers the outside of the first tubular body 10 in the radial direction C and is configured to be expandable and contractable in the radial direction C. Specifically, the expansion body 30 of this embodiment is a balloon made of a membrane body that covers the periphery of the first tubular body 10. The expansion body 30 of this embodiment defines an annular fluid storage space 30a between the outer surface of the first tubular body 10. The expansion body 30 of this embodiment can be expanded outward in the radial direction C by supplying fluid to the fluid storage space 30a. In addition, the expansion body 30 of this embodiment can be contracted inward in the radial direction C by discharging fluid from the fluid storage space 30a. More specifically, the expansion body 30 of this embodiment includes an expansion body portion 35 that can be expanded and contracted, a distal side fixing portion 36 that is connected to the distal side of the expansion body portion 35 and fixed to the shaft portion 3, and a proximal side fixing portion 37 that is connected to the proximal side of the expansion body portion 35 and fixed to the shaft portion 3. The central portion of the expansion body 35 of the expansion body 30 of this embodiment in the insertion / removal direction A is a peripheral wall portion 35a that is substantially cylindrical in the expanded state. In addition, both ends of the expansion body 35 of the expansion body 30 of this embodiment in the insertion / removal direction A are tapered portions 35b that decrease in diameter toward both ends. As shown in Fig. 2, the tapered portion 35b can be configured in a hemispherical shape. However, the shape of the tapered portion 35b is not limited to a hemispherical shape, and may be, for example, a conical shape.

[0040] Moreover, the expansion body 30 is configured to house or be able to house therein the light irradiation unit 200. Specifically, the first tubular body 10 is disposed inside the expansion body 30 of this embodiment. The light irradiation unit 200 can be housed in the housing space 10a of the first tubular body 10.

[0041] As shown in Figs. 2 to 4, the extension body 30 includes a light-transmitting window portion 31 and a light-shielding portion 32. As shown in Fig. 4, the light-transmitting window portion 31 is arranged in only a part of the circumferential direction B. The light-transmitting window portion 31 is configured to transmit light from the light irradiating portion 200 accommodated in the accommodation space 10a to the outside in the radial direction C. The light-shielding portion 32 is arranged adjacent to the light-transmitting window portion 31 in the insertion / removal direction A and the circumferential direction B. The transmittance of the light-shielding portion 32 to the outside in the radial direction C from the light irradiating portion 200 accommodated in the accommodation space 10a (hereinafter, simply referred to as "the transmittance of the light-shielding portion 32") is smaller than the transmittance of the light-transmitting window portion 31 to the outside in the radial direction C from the light irradiating portion 200 accommodated in the accommodation space 10a (hereinafter, simply referred to as "the transmittance of the light-transmitting window portion 31").

[0042] In this embodiment, the light-transmitting window section 31 and the light-shielding section 32 of the extension body 30 are realized by the layered relationship of the base body 90a and the covering layer 90b. Specifically, the extension body 30 of this embodiment includes a base body 90a and a covering layer 90b coated on the outer surface of the base body 90a. The base body 90a is made of a light-transmitting material that allows light from the light emitting section 200 housed in the accommodation space 10a to pass outward in the radial direction C. The covering layer 90b is made of a light-transmitting limiting material whose transmittance of light from the light emitting section 200 housed in the accommodation space 10a to the outside in the radial direction C is smaller than that of the base body 90a. In the light-transmitting window section 31 of the extension body 30 of this embodiment, the base body 90a is not covered with the covering layer 90b, and is made of only the base body 90a. In contrast, the light-shielding portion 32 of the extension body 30 of this embodiment is configured by the base body 90a covered with the covering layer 90b, and is composed of the base body 90a and the covering layer 90b.

[0043] In other words, the light-transmitting window portion 31 of the extension body 30 of this embodiment is the light-transmitting portion 2a in which the base body 90a is not covered with the covering layer 90b, and the light-shielding portion 32 of the extension body 30 of this embodiment is the light-transmitting limiting portion 2b in which the base body 90a is covered with the covering layer 90b.

[0044] Furthermore, the expansion body 30 is provided with another light-transmitting portion 2a in addition to the light-transmitting portion 2a of the light-transmitting window portion 31 described above. The expansion body 30 has exposed ends 33 that are endless in the circumferential direction B, which are portions of the base body 90a that are not covered by the covering layer 90b, as the other light-transmitting portion 2a, at both ends in the insertion / removal direction A.

[0045] More specifically, the light-transmitting window portion 31 of the expansion body 30 of this embodiment is provided in the expansion main body portion 35. In contrast, the exposed end portion 33 of the expansion body 30 of this embodiment is provided in each of the distal fixing portion 36 and the proximal fixing portion 37. As described above, the expansion body 30 of this embodiment includes the expansion main body portion 35, the distal fixing portion 36, and the proximal fixing portion 37. The first tubular body 10 of this embodiment includes a protruding portion 15 that protrudes distally from the distal end 20a1 of the second tubular body 20 described later. The expansion main body portion 35 covers the outer periphery in the radial direction C of the protruding portion 15 of the first tubular body 10. The expansion main body portion 35 can expand and contract in the radial direction C outside the radial direction C of the protruding portion 15. The distal fixing portion 36 is connected to the distal side of the expansion main body portion 35. The distal fixing portion 36 is connected to the tapered portion 35b on the distal side of the expanding main body portion 35. The distal fixing portion 36 is fixed to the outer surface of the distal end portion 15a of the protruding portion 15 of the first tubular body 10 by adhesion or the like. The distal fixing portion 36 is outside the radial direction C of the protruding portion 15 of the first tubular body 10 and does not expand or contract in the radial direction C. The proximal fixing portion 37 is connected to the proximal side of the expanding main body portion 35. The distal fixing portion 36 is connected to the tapered portion 35b on the proximal side of the expanding main body portion 35. The proximal fixing portion 37 is fixed to the outer surface of the distal end portion 20a of the second tubular body 20 described later by adhesion or the like. The proximal fixing portion 37 is outside the radial direction C of the protruding portion 15 of the first tubular body 10 and does not expand or contract in the radial direction C.

[0046] As described above, the light transmitting portion 2a of the expansion body 30 of this embodiment is the light transmitting window portion 31 and the exposed end portion 33. The light transmission limiting portion 2b of the expansion body 30 of this embodiment is the portion excluding the light transmitting window portion 31 and the exposed end portion 33.

[0047] The expansion body 30 of this embodiment does not include a light-transmitting portion 2a other than the light-transmitting window portion 31 and the exposed end portion 33, but is not limited to this configuration. The expansion body 30 may include a light-transmitting portion 2a other than the light-transmitting window portion 31 and the exposed end portion 33. The expansion body 30 may include a viewing window portion as the light-transmitting portion 2a that is not continuous with the light-transmitting window portion 31 and is disposed on the proximal side of the light-transmitting window portion 31, separated from the light-transmitting window portion 31, with a light-shielding portion 32 sandwiched therebetween. By providing such a viewing window portion, the light-transmitting window portion 31 and the lesion portion that the light-transmitting window portion 31 comes into contact with can be monitored from inside the expansion body 30 through the viewing window portion using the endoscope device 101 (see FIG. 1).

[0048] The coating layer 90b of the present embodiment may be, for example, a coating material coated on the outer surface of the base body 90a, and the method of applying the coating material to the outer surface of the base body 90a is not particularly limited. The coating material constituting the coating layer 90b may be applied to the outer surface of the base body 90a by, for example, a dipping method, a spray coating method, a roll coating method, a screen printing method, a vacuum deposition method, a low vacuum sputtering method, or the like.

[0049] The base body 90a may be made of, for example, a transparent resin material as a light transmitting material. Examples of the resin material constituting the base body 90a include polyethylene terephthalate (PET), polyurethane, polyamide, polyamide elastomer, etc. The base body 90a may be made of a single layer of transparent resin material, or may be a laminate in which multiple layers of transparent resin material are laminated.

[0050] The material of the coating layer 90b is not particularly limited, and may be, for example, various metal materials such as titanium oxide, barium sulfate, zinc oxide, silver, and aluminum. The coating layer 90b may be a resin containing particles of the above-mentioned metal materials, carbon black, or the like. The maximum thickness T1max of the thickness T1 of the coating layer 90b may be, for example, 1 / 6 to 3 times the minimum thickness T2min of the thickness T2 of the base body 90a. The base body 90a of this embodiment has a substantially constant thickness regardless of the position in the circumferential direction B in a cross-sectional view (see FIG. 4) perpendicular to the insertion / removal direction A. Therefore, the minimum thickness T2min of the base body 90a of this embodiment is the thickness T2 of the base body 90a at any position in the circumferential direction B.

[0051] In addition, it is preferable that the transmittance of the covering layer 90b is smaller than the reflectance and absorptance of the covering layer 90b, respectively. In this way, it is possible to further prevent the light from the light irradiating unit 200 from penetrating the light shielding unit 32 and irradiating normal tissue, thereby preventing damage to the normal tissue.

[0052] Of the light from the light irradiation unit 200 accommodated in the accommodation space 10a of the first tubular body 10, the light that transmits through the first tubular body 10 is mainly emitted to the outside in the radial direction C of the expansion body 30 through the light-transmitting window portion 31 of the expansion body 30 that is provided in only a part of the circumferential direction B. In other words, by providing the light-transmitting window portion 31 in only a part of the circumferential direction B, the expansion body 30 has a light distribution characteristic in which the light emitted from the inside of the expansion body 30 to the outside in the radial direction C is mainly limited to a part of the circumferential direction B.

[0053] As described above, the first tubular body 10 of this embodiment includes a closing wall 15b that closes the distal side of the accommodation space 10a. The exposed end 33 located at the distal fixing part 36 of the expandable body 30 of this embodiment is located only distal to the closing wall 15b. Therefore, the exposed end 33 located at the distal fixing part 36 of this embodiment is a light-transmitting part 2a in which the base body 90a is not covered with the covering layer 90b, but does not overlap with the light irradiating part 200 in the insertion / removal direction A. Therefore, light from the light irradiating part 200 is unlikely to pass through the exposed end 33 located at the distal fixing part 36.

[0054] In addition, the proximal fixing portion 37 of the expansion body 30 of this embodiment is fixed to the outer surface of the second tubular body 20 described later. That is, the inside in the radial direction C of the exposed end portion 33 located at the proximal fixing portion 37 of the expansion body 30 of this embodiment is covered by the second tubular body 20. Therefore, the exposed end portion 33 located at the proximal fixing portion 37 of this embodiment is a light transmitting portion 2a in which the base body 90a is not covered by the covering layer 90b, but since the inside is covered by the second tubular body 20, the light from the light irradiation portion 200 does not easily transmit through the exposed end portion 33 located at the proximal fixing portion 37.

[0055] Next, the reflectance and absorptance of the base body 90a and the covering layer 90b in the expansion body 30 of this embodiment will be described. The "reflectance" and "absorbance" referred to here mean the reflectance and absorptance from the inside to the outside in the radial direction C of the light from the light irradiating unit 200 housed in the housing space 10a.

[0056] The covering layer 90b may be, for example, a reflector having a reflectance higher than that of the base body 90a and an absorptance lower than that of the base body 90a. In this way, the light from the light emitting unit 200 is easily reflected by the light shielding unit 32 toward the light transmitting window unit 31. Therefore, the energy of the light emitted from the light transmitting window unit 31 to the outside in the radial direction C can be increased.

[0057] However, the covering layer 90b may be an absorber having a reflectance lower than that of the base body 90a and an absorptance higher than that of the base body 90a. When the light from the light irradiating unit 200 is reflected by the light shielding unit 32, there is a possibility that the light is repeatedly reflected within the extension body 30. The transmittance of the light shielding unit 32 is preferably 0%, but is not necessarily 0%. That is, every time the light is reflected by the light shielding unit 32 of the extension body 30, transmitted light that passes through the light shielding unit 32 may be generated. Therefore, it is not preferable to repeatedly reflect the light by the light shielding unit 32. Therefore, by making the covering layer 90b an absorber, it is possible to suppress damage to normal tissue caused by the light from the light irradiating unit 200 passing through the light shielding unit 32 and irradiating the normal tissue.

[0058] Furthermore, the covering layer 90b may be a reflector-absorber having a reflectance higher than that of the base body 90a and an absorptance higher than that of the base body 90a, thereby achieving both the effect as a reflector and the effect as an absorber.

[0059] As shown in FIG. 2 and FIG. 3, the second tubular body 20 covers the circumference of the first tubular body 10 in the radial direction C. More specifically, the first tubular body 10 of this embodiment includes a protruding portion 15 that is disposed protruding further distally from the distal end 20a1 of the second tubular body 20 as described above. The first tubular body 10 of this embodiment also includes a protruding portion 16 that is disposed protruding further proximally from the proximal end 20b1 of the second tubular body 20. The first tubular body 10 and the second tubular body 20 are disposed concentrically. The first tubular body 10 and the second tubular body 20 of this embodiment are fixed to the hub 40 so as to be concentric, but are not limited to this configuration. The first tubular body 10 and the second tubular body 20 may be directly connected to each other by a connecting portion that connects the outer surface of the first tubular body 10 and the inner surface of the second tubular body 20 in a concentric positional relationship, for example.

[0060] The expansion body 30 of this embodiment is fixed to the outer surface of the first tubular body 10 and the outer surface of the second tubular body 20, spanning the outer surface of the first tubular body 10 and the outer surface of the second tubular body 20. More specifically, the expansion body 30 of this embodiment includes an expansion main body portion 35, a distal side fixing portion 36, and a proximal side fixing portion 37, as described above. The distal side fixing portion 36 of the expansion body 30 is fixed to the outer surface of the distal end portion 15a of the protrusion 15 of the first tubular body 10 by adhesion or the like. The proximal side fixing portion 37 of the expansion body 30 is fixed to the outer surface of the distal end portion 20a of the second tubular body 20 by adhesion or the like.

[0061] More specifically, a distal protection part 80, which will be described later, is attached to the distal end of the first tubular body 10 of this embodiment. The distal protection part 80 includes a tube part 80a and a distal wall part 80b that covers the distal side of the tube part 80a. The distal protection part 80 is attached to the distal end of the first tubular body 10 by fitting the tube part 80a to the outside of the distal end of the first tubular body 10. That is, an annular step is formed between the outer surface of the first tubular body 10 and the outer surface of the tube part 80a of the distal protection part 80. The distal side fixing part 36 of the expansion body 30 of this embodiment is joined onto the outer surface of the first tubular body 10. It is preferable that the outer surface of the distal side fixing part 36 in the radial direction C is located inside the outer surface of the tube part 80a of the distal protection part 80 in the radial direction C. Moreover, it is more preferable that the outer surface of the distal fixing part 36 in the radial direction C is disposed flush with the outer surface of the tube part 80a of the distal protection part 80 so as to prevent the above-mentioned step from being formed. In this manner, by preventing the distal fixing part 36 from protruding outward in the radial direction C from the outer surface of the tube part 80a of the distal protection part 80, it is possible to prevent the distal end surface of the distal fixing part 36 from getting caught on biological tissue or a medical instrument such as an endoscope apparatus 101 (see FIG. 1) used together with the light irradiation device 1 when the light irradiation device 1 moves in the insertion direction A1. It is preferable that the distal side fixing part 36 is configured so as not to protrude outward in the radial direction C from the outer surface of the tubular part 80a of the distal protection part 80; however, as long as the light irradiation device 1 does not get caught when the light irradiation device 1 is inserted into or removed from a medical instrument such as an endoscopic apparatus 101 (see FIG. 1), the outer surface of the distal side fixing part 36 may protrude outward in the radial direction C from the outer surface of the tubular part 80a of the distal protection part 80.

[0062] In addition, the distal end 20a of the second tubular body 20 of this embodiment is composed of a thin-diameter portion 22b having an outer diameter smaller than that of the proximal main body tube portion 22a. That is, in the second tubular body 20, an annular step is formed between the outer surface of the main body tube portion 22a and the outer surface of the thin-diameter portion 22b. The proximal fixing portion 37 of the expansion body 30 of this embodiment is joined onto the outer surface of the thin-diameter portion 22b as the distal end portion 20a of the second tubular body 20. That is, the expansion body 30 of the insertion main body portion 2 of this embodiment is disposed on the distal end portion 20a side of the second tubular body 20. It is preferable that the outer surface of the proximal fixing portion 37 in the radial direction C is located inside the outer surface of the main body tube portion 22a of the second tubular body 20 in the radial direction C. Moreover, it is more preferable that the outer surface of the proximal fixing part 37 in the radial direction C is arranged to be flush with the outer surface of the main body tube part 22a of the second tubular body 20 so as to avoid the formation of the above-mentioned step. In this manner, by preventing the proximal fixing part 37 from protruding outward in the radial direction C from the outer surface of the main body tube part 22a of the second tubular body 20, it is possible to prevent the proximal end surface of the proximal fixing part 37 from getting caught on biological tissue or a medical instrument such as an endoscope apparatus 101 (see FIG. 1) used together with the light irradiation device 1 when the light irradiation device 1 moves in the removal direction A2. It is preferable that the proximal fixing portion 37 is configured so as not to protrude outward in the radial direction C from the outer surface of the main body tube portion 22a of the second tubular body 20; however, as long as the light irradiation device 1 does not get caught when the light irradiation device 1 is inserted into or removed from a medical instrument such as an endoscopic apparatus 101 (see FIG. 1), the outer surface of the proximal fixing portion 37 may protrude outward in the radial direction C from the outer surface of the main body tube portion 22a.

[0063] The expansion body 30 of this embodiment is fixed to the first tubular body 10 and the second tubular body 20 so as to be concentric with the first tubular body 10 and the second tubular body 20 in the expanded state. However, the expansion body 30 does not have to be concentric with the first tubular body 10 and the second tubular body 20 in the expanded state. In other words, the expansion body 30 may be fixed to the first tubular body 10 and the second tubular body 20 so as to be in an eccentric state in which the central axis of the expansion body 30 does not coincide with that of the first tubular body 10 and the second tubular body 20 in the expanded state.

[0064] Between the first tubular body 10 and the second tubular body 20, a flow path 21 is defined for a fluid to be supplied to a fluid accommodation space 30a defined between the expandable body 30 and the outer surface of the first tubular body 10. The fluid to be supplied to the fluid accommodation space 30a may be a liquid such as physiological saline or a gas such as air. The flow path 21 has a distal opening 21a at the position of the distal end 20a1 of the second tubular body 20, and communicates with the fluid accommodation space 30a at the distal opening 21a. The flow path 21 also has a proximal opening 21b that communicates with a hub inner flow path 40b defined by the hub 40 described later. That is, the supply of the fluid to the fluid accommodation space 30a is performed from the hub inner flow path 40b of the hub 40 through the flow path 21. Conversely, the discharge of the fluid from the fluid accommodation space 30a is performed from the flow path 21 through the hub inner flow path 40b of the hub 40.

[0065] The material for forming the second tubular body 20 is not particularly limited, and may be, for example, a resin material. The resin material for forming the second tubular body 20 may be, for example, any of the materials exemplified above as the material for forming the first tubular body 10. The second tubular body 20 may be a metal such as stainless steel, iron, nickel-titanium alloy, aluminum, etc., or may be a combination of a resin material and a metal.

[0066] The shaft portion 3 of the light irradiation device 1 of this embodiment has a double-tube structure including a first tubular body 10 and a second tubular body 20 arranged concentrically, but is not limited to this configuration. The shaft portion 3 of the light irradiation device 1 may be only one tubular body including another lumen capable of supplying a fluid to the expansion body 30 in addition to the accommodation space 10a.

[0067] As shown in FIG. 2, the insertion body 2 of the light irradiation device 1 may include a distal protection part 80. As described above, the distal protection part 80 of this embodiment includes a tube part 80a and a distal wall part 80b covering the distal side of the tube part 80a. The distal protection part 80 constitutes the distal end of the light irradiation device 1. The distal protection part 80 may be made of, for example, an elastic body. As shown in FIG. 2, the distal protection part 80 may be fixed to the distal end of the first tubular body 10. By providing such a distal protection part 80, it is possible to prevent the distal end of the light irradiation device 1 from damaging biological tissues around the inner cavity.

[0068] As shown in FIG. 3, the protector 300 covers the outer surface of the expansion body 30 as the insertion body 301 so as to straddle the boundary between the light transmitting portion 2a and the light transmission limiting portion 2b adjacent to each other in the insertion / removal direction A, as described above. More specifically, the protector 300 of this embodiment covers the outer surface of the expansion body 30 so as to straddle the boundaries BL1 and BL2 between the light blocking portion 32 of the expansion body 30 and the exposed end portion 33 of the expansion body 30. As described above, the light blocking portion 32 of the expansion body 30 is the light transmission limiting portion 2b in which the base body 90a is covered by the covering layer 90b. Moreover, the exposed end portion 33 of the expansion body 30 is the light transmitting portion 2a in which the base body 90a is not covered by the covering layer 90b. Moreover, the exposed end portion 33 of this embodiment is located at the distal fixing portion 36 and the proximal fixing portion 37, respectively. The exposed end 33 located at the distal fixing portion 36 is adjacent to the light-shielding portion 32 on the distal side of the distal end of the light-shielding portion 32. Moreover, the exposed end 33 located at the proximal fixing portion 37 is adjacent to the light-shielding portion 32 on the proximal side of the proximal end of the light-shielding portion 32. The protective body 300 can prevent the covering layer 90b from peeling off from the positions of the boundaries BL1, BL2 in the expansion body 30.

[0069] More specifically, in the expansion body 30 of this embodiment, there are four boundaries between the light transmitting portion 2a and the light transmission limiting portion 2b in the insertion / removal direction A: boundaries BL3 and BL4 located at the expansion main body portion 35 of the expansion body 30, a boundary BL1 located at the distal fixing portion 36 of the expansion body 30, and a boundary BL2 located at the proximal fixing portion 37 of the expansion body 30. The protective body 300 covers the outer surface of the expansion body 30 so as to straddle two boundaries BL1 and BL2 of these four boundaries BL1 to BL4.

[0070] As described above, the boundaries BL1 and BL2 across which the protector 300 of this embodiment is disposed are located in the expansion body 30. However, the protector 300 may be disposed across the boundary between the light transmitting portion 2a and the light transmission limiting portion 2b formed in the insert 301 separate from the expansion body 30.

[0071] 2 and 3, the light irradiation device 1 of this embodiment includes a first protector 300a that covers the boundary BL1, and a second protector 300b that covers the boundary BL2. Hereinafter, when there is no need to distinguish between the first protector 300a and the second protector 300b, they will simply be referred to as "protector 300."

[0072] The first protective body 300a may be, for example, an annular body that covers the outside in the radial direction C of the distal fixing part 36 joined onto the outer surface of the first tubular body 10. The annular body as the first protective body 300a may be attached to the outside in the radial direction C of the distal fixing part 36 so as to sandwich the distal fixing part 36 including the exposed end part 33 between the outer surface of the first tubular body 10 and the annular body in the radial direction C.

[0073] Furthermore, the second protective body 300b may be, for example, an annular body that covers the outside in the radial direction C of the proximal fixing part 37 joined onto the outer surface of the second tubular body 20. The annular body as the second protective body 300b may be attached to the outside in the radial direction C of the proximal fixing part 37 so as to sandwich the proximal fixing part 37 including the exposed end part 33 between the outer surface of the second tubular body 20 and the proximal fixing part 37 in the radial direction C.

[0074] The protective body 300 may include a metal having X-ray contrast. The protective body 300 may be, for example, composed of only a metal having X-ray contrast, or may be configured to include a metal having X-ray contrast in a resin. Examples of the metal having X-ray contrast include metals having high X-ray opacity, such as platinum, gold, iridium, and tungsten. Examples of the resin containing the metal having X-ray contrast may include the resin materials exemplified above as the material for forming the first tubular body 10. By making the protective body 300 include a metal having X-ray contrast, the position of the protective body 300, that is, the position near the light-transmitting window portion 31 in the insertion / removal direction A, can be confirmed through an X-ray image. In addition, the protective body 300 may include a metal having X-ray contrast only in a position in the circumferential direction B. The position in the circumferential direction B of the protective body 300 including the metal having X-ray contrast is arranged to overlap with the light-transmitting window portion 31 of the expansion body 30 in the circumferential direction B. In this way, the position of the light transmitting window portion 31 of the light irradiation device 1 in the circumferential direction B can be confirmed through an X-ray image.

[0075] The protective body 300 may be made of resin. The resin material used to form the protective body 300 is not particularly limited, but may be, for example, any of the resin materials listed above as examples of the material used to form the first tubular body 10.

[0076] When the protective body 300 is made of resin, it is preferable to separately provide a marker member containing a metal having X-ray contrast. However, as described above, even if the protective body 300 is configured to contain a metal having X-ray contrast, a marker member containing a metal having X-ray contrast may be provided separately from the protective body 300.

[0077] The first protective body 300a is disposed so as to straddle the boundary BL1 located at the distal fixing portion 36 of the expansion body 30 in the insertion / removal direction A. More specifically, the first protective body 300a is disposed so as to straddle the boundary BL1 located at the distal fixing portion 36 and extending endlessly in the circumferential direction B in the insertion / removal direction A over the entire area of ​​the circumferential direction B. The second protective body 300b is disposed so as to straddle the boundary BL2 located at the proximal fixing portion 37 of the expansion body 30 in the insertion / removal direction A. More specifically, the second protective body 300b is disposed so as to straddle the boundary BL2 located at the proximal fixing portion 37 and extending endlessly in the circumferential direction B in the insertion / removal direction A over the entire area of ​​the circumferential direction B.

[0078] As described above, the exposed end 33 located at the distal fixing portion 36 of the expandable body 30 in this embodiment is located only distal to the closing wall 15b of the first tubular body 10. In other words, the boundary BL1 between the exposed end 33 located at the distal fixing portion 36 of the expandable body 30 and the light-shielding portion 32 is also located distal to the closing wall 15b. Therefore, the first protective body 300a in this embodiment covers the boundary BL1 distal to the closing wall 15b.

[0079] In this embodiment, as described above, the light irradiator 201 including the light irradiator 200 is inserted in the insertion direction A1 until the distal end of the light irradiator 201 abuts against the closed wall 15b of the first tubular body 10. In this state, the first protector 300a is located distal to the light irradiator 200 without overlapping with the light irradiator 200 in the insertion / removal direction A. In this state, the second protector 300b is located proximal to the light irradiator 200 without overlapping with the light irradiator 200 in the insertion / removal direction A.

[0080] In this embodiment, the inner diameter of the first protective body 300a is smaller than the inner diameter of the second protective body 300b, and the outer diameter of the first protective body 300a is smaller than the outer diameter of the second protective body 300b.

[0081] The light irradiation device 1 of the present embodiment includes a first protective body 300a and a second protective body 300b as the protective body 300, but may include only one of them. However, from the viewpoint of suppressing peeling of the covering layer 90b from the boundaries BL1 and BL2, it is preferable that the light irradiation device 1 includes both the first protective body 300a and the second protective body 300b.

[0082] As shown in Fig. 2, the handheld operation unit 1b of the light irradiation device 1 may include a hub 40. The hub 40 of this embodiment is attached to the proximal end 20b of the second tubular body 20. The hub 40 of this embodiment holds the protruding portion 16 of the first tubular body 10, which protrudes proximally from the second tubular body 20, so that the first tubular body 10 and the second tubular body 20 are concentric. Furthermore, the hub 40 holds the protruding portion 16 of the first tubular body 10 so that the light irradiator 201 can be inserted into the proximal opening 10a1 of the accommodation space 10a of the first tubular body 10.

[0083] 2, the hub 40 includes a hub body 41 and a connection portion 42 that is screwed into the hub body 41. The hub body 41 includes a port portion 40a to which a fluid supply device 105 (see FIG. 1) such as a syringe can be connected. The fluid supply device 105 (see FIG. 1) that is connected to the port portion 40a can supply fluid to the fluid accommodation space 30a of the expandable body 30 through the hub internal flow path 40b and the flow path 21.

[0084] The connection part 42 holds the light irradiator 201 so as to surround the light irradiator 201. The connection part 42 is connected to the hub body 41 by screwing in a state in which the light irradiator 201 is inserted into the accommodation space 10a of the first tubular body 10. This fixes the relative positions of the light irradiator 201 and the light irradiation device 1 in the insertion / removal direction A. Conversely, by releasing the screwing between the hub body 41 and the connection part 42, the light irradiator 201 can be removed from the first tubular body 10 of the light irradiation device 1.

[0085] 2, the handheld operation unit 1b of the light irradiation device 1 may include an operation unit 50. The operation unit 50 may be fixed on the outer surface of the second tubular body 20. An operator of the light irradiation device 1 can move the light irradiation device 1 in the insertion / removal direction A and rotate the light irradiation device 1 in the circumferential direction B by holding and operating the operation unit 50.

[0086] As shown in Fig. 2, the handheld operation unit 1b of the light irradiation device 1 may include a fixing part 60. As shown in Fig. 1, the fixing part 60 is used to fix the light irradiation device 1 and an endoscope apparatus 101 (see Fig. 1). More specifically, the light irradiation device 1 of this embodiment can be attached to the endoscope apparatus 101 by fixing the fixing part 60 to the endoscope apparatus 101 in a state where a part distal to the fixing part 60 is inserted into a treatment tool channel of the endoscope apparatus 101. The inner cavity of the fixing part 60 is configured to have an inner diameter that allows the protection body 300 to pass through.

[0087] The biological insertion device according to the present disclosure is not limited to the specific configuration shown in the above-mentioned embodiment, and various modifications, changes, and combinations are possible without departing from the scope of the claims. The insert 301 of the biological insertion device according to the present disclosure may be configured to include a light transmitting portion 2a and a light transmission limiting portion 2b adjacent to each other in the insertion / removal direction A, and the insert 301 is not limited to the expandable body 30 of the above-mentioned embodiment. In other words, the insert 301 of the biological insertion device according to the present disclosure may be, for example, a tubular body including a light transmitting portion 2a and a light transmission limiting portion 2b adjacent to each other in the insertion / removal direction A. The protector 300 may be configured to cover the boundary between the light transmitting portion 2a and the light transmission limiting portion 2b of this tubular body. This tubular body may be configured to be continuous with the second tubular body 20 of the shaft portion 3 described above in the insertion / removal direction A. [Industrial Applicability]

[0088] The present disclosure relates to bioinsertion devices. [Explanation of symbols]

[0089] 1: Light irradiation device (an example of a bioinsertable device) 1a: Insertion section 1b: Handheld control unit 2: Insertion body part 2a: Light transmission part 2b: Light transmission limiting section 3: Shaft section 10: First tubular body 10a: Containment space 10a1: Proximal opening 15: Distal protrusion 15a: Distal end 15b: Enclosed wall 16: Proximal protrusion 20:Second tubular body 20a: Distal end 20a1: Distal end 20b: Proximal end 20b1: Proximal end 21: Flow path 21a: Distal opening 21b: Proximal opening 22a: Main body tube 22b: Narrow diameter part 30: Expander (an example of an insert) 30a: Fluid containing space 31: Light transmitting window 32: Shading part 33:Exposed end 35: Extended main body 35a: Peripheral wall part 35b: Tapered section 36: Distal fixation part 37: Proximal fixation part 40: Hub 40a: Port section 40b: Channel inside the hub 41: Hub body 42: Connection 50:Operation unit 60: Fixed part 80: Distal protection section 80a:Cylinder part 80b: Distal wall 90a: Base body 90b: Covering layer 100: Endoscope system 101: Endoscopic device 102: Control device 102a: Light source section 102b: Processor section 103: Display section 104:Light source device 105:Fluid supply equipment 200: Light irradiation unit 201: Light irradiator 202: Optical transmission components 300: Protective body 300a: 1st protector 300b:Second protector 301: Insert A: Insertion / removal direction A1: Insertion direction A2: Removal direction B: Circumferential direction C: Radial direction BL1 to BL4: Boundaries between the light transmitting portion and the light transmitting restricting portion of the insert in the insertion / removal direction O1: Central axis of the insertion body T1: Thickness of the coating layer T2: Thickness of the base body

Claims

1. An insert that can be inserted into a living body; A protective body covering an outer surface of the insert, The insert comprises: A base body; A coating layer that covers the outside of the base body, The insert comprises: a light transmitting portion where the base body is not covered with the covering layer; a light transmission limiting portion in which the base body is covered with the covering layer; The light transmitting portion and the light transmission limiting portion are adjacent to each other in the insertion / removal direction of the insert body, The biological insertion device, wherein the protector covers the outer surface of the insertion body so as to straddle the boundary between the light transmitting portion and the light transmission limiting portion in the insertion / removal direction.

2. The insert contains or is capable of containing a light irradiation unit therein, The biological insertion device according to claim 1 , wherein the transmittance of the covering layer to the light from the light emitting unit is lower than the transmittance of the base body to the light from the light emitting unit.

3. The biological insertion device according to claim 1 or 2, wherein the insertion body is an expandable body capable of expanding and contracting.

4. A long shaft portion extends through the inside of the expansion body, The expansion body is an expandable body portion capable of expanding and contracting; a distal fixing portion connected to a distal side of the expansion body portion and fixed to the shaft portion; a proximal fixing portion connected to a proximal side of the expansion body portion and fixed to the shaft portion, the boundary is located on the expanded body portion and on at least one of the distal fixation portion and the proximal fixation portion; The biological insertion device according to claim 3 , wherein the protective body covers an outer surface of the expansion body so as to span the boundary located at least one of the distal fixation portion and the proximal fixation portion of the expansion body.

5. The biological insertion device according to claim 1 or 2, wherein the insertion body is a tubular body.

6. The biological insertion device according to claim 1 , wherein the protective body includes a metal having X-ray contrast properties.

7. The biological insertion device according to claim 1 or 2, wherein the protective body is made of a resin.

Images