Oral cavity product

Abstract

To provide an oral cavity product which is a composition for an oral cavity having good flavor and reduced irritation, satisfies both stability and uniformity of foam and foam dischargeability with time, and discharges the composition from a container in a foam state.SOLUTION: Provided is an oral cavity product, which includes: an oral cavity composition comprising (A) a polyoxyethylene alkyl ether and (B) an amphoteric surfactant, wherein the content of the ingredient (A) is 0.5 to 5 mass% and the mass ratio (A) / (B) of the content of the ingredient (A) to the content of the ingredient (B) is 10 to 70; and a foam-forming container in which the oral composition is accommodated; wherein the oral composition is discharged in a foam form from the container.SELECTED DRAWING: None

Description

Technical Field

[0001] The present invention relates to an oral care product in which an oral composition is discharged in a foamy state from a container.

Background Art

[0002] As an oral composition, an oral composition that is easy to use, has a good aroma, and causes little irritation is desired.

[0003] In the case of an oral composition that is discharged in a foamy state from a container, the foam spreads easily in the oral cavity and is difficult to remain in the mouth even with a light rinse. Therefore, it is suitable for toothbrushing by caregivers and others whose oral function has declined and who have difficulty rinsing.

[0004] When an oral composition is taken out of a container and placed on a toothbrush, from the viewpoint of the feeling of use, it is important that the foam is stable and uniform. For this purpose, it is necessary to blend a foam stabilizing component such as hydroxyethyl cellulose. However, when these components are contained, there is a risk that the usability deteriorates due to non-discharge from the container during continuous use. From the above points, in the case of an oral care product in which an oral composition is discharged in a foamy state from a container, both the stability and uniformity of the foam and the foam dischargeability over time have been required.

Prior Art Documents

Patent Documents

[0005]

Patent Document 1

Patent Document 2

Summary of the Invention

Problems to be Solved by the Invention

[0006] The present invention has been made in view of the above circumstances, and provides an oral composition having good flavor and less irritation, and an oral product in which the oral composition that achieves both the stability and uniformity of foam and the foam discharge property over time is discharged in a foamy state from a container. [Means for Solving the Problems]

[0007] As a result of intensive studies to achieve the above object, the present inventors have found that the above problems can be solved by limiting the amount of (A) polyoxyethylene alkyl ether and combining (A) polyoxyethylene alkyl ether and (B) amphoteric surfactant in an optimal balance, and thus have arrived at the present invention.

[0008] Therefore, the present invention provides the following oral products. 1. An oral composition containing (A) polyoxyethylene alkyl ether and (B) amphoteric surfactant wherein the content of the above component (A) is 0.5 to 5% by mass, and the mass ratio (A) / (B) of the content of the above component (A) to component (B) is 10 to 70, and a foam-forming container containing the oral composition, and an oral product in which the oral composition is discharged in a foamy state from the container. 2. The oral product according to 1, wherein the content of anionic surfactant is 1% by mass or less. 3. The oral product according to 1 or 2, wherein the content of ethanol is 0.5% by mass or less. 4. The oral product according to any one of 1 to 3, wherein the water content is 70% by mass or more in the composition. [Advantages of the Invention]

[0009] According to the present invention, it is possible to provide an oral composition having good flavor and less irritation, and to achieve both the stability and uniformity of foam and the foam discharge property over time, and to provide an oral product in which the oral composition is discharged in a foamy state from a container.

[0010] Hereinafter, the present invention will be described in detail. The oral product of the present invention is (A) polyoxyethylene alkyl ether and (B) an amphoteric surfactant and contains the content of the above component (A) is 0.5 to 5% by mass, the mass ratio (A) / (B) of the content of the above component (A) and component (B) is 10 to 70, an oral composition, and a foam-forming container containing this oral composition, and the oral product is such that the oral composition is discharged in a foamy state from the container.

[0011] [Component (A)] The component (A) of the present invention is polyoxyethylene alkyl ether. The component (A) can be used alone or in combination of two or more. The carbon chain length of the hydrocarbon group of the alkyl group is preferably 10 to 22, more preferably 16 to 22 carbon atoms. Examples of polyoxyethylene alkyl ethers include polyoxyethylene lauryl ether, polyoxyethylene cetyl ether, polyoxyethylene stearyl ether, polyoxyethylene oleyl ether, polyoxyethylene behenyl ether, and the like. Among these, polyoxyethylene behenyl ether and polyoxyethylene cetyl ether are preferred.

[0012] The average number of added moles of the polyoxyethylene chain (average number of added moles of ethylene oxide) is preferably 10 to 50, more preferably 15 to 30. By setting it within such a range, foaming is good and the foam is easily spread in the oral cavity.

[0013] [Component (B)] Component (B) of the present invention is an amphoteric surfactant, which contributes to improving the stability and uniformity of foam. Component (B) can be used alone or in combination of two or more. Examples of Component (B) include betaine type such as alkyl betaine and fatty acid amide propyl betaine, and imidazolinium betaine (alkyl imidazole) type amphoteric surfactants such as alkyl imidazolinium betaine and 2-alkyl-N-carboxymethyl-N-hydroxyethyl imidazolinium betaine. Among them, imidazolinium betaine is preferred from the viewpoints of flavor development and foam stabilization, and 2-alkyl-N-carboxymethyl-N-hydroxyethyl imidazolinium betaine is more preferred.

[0014] The content of Component (A) is 0.5 to 5% (mass%, the same hereinafter) in the composition, preferably 0.5 to 3%, and more preferably 1 to 2%. If the content of Component (A) is less than 0.5%, the fragrance components cannot be solubilized, and the stability and uniformity of the foam deteriorate. If it exceeds 5%, the uniformity and flavor development of the foam deteriorate.

[0015] The content of Component (B) is preferably 0.01 to 0.5% in the composition, more preferably 0.01 to 0.3%, and even more preferably 0.05 to 0.2%. By setting the content within the above range, the uniformity of the foam is further improved. By setting it to 0.5% or less, bitterness is more suppressed and flavor development is more improved.

[0016] The mass ratio (A) / (B) of the contents of Component (A) and Component (B) is 10 to 70, preferably 15 to 50, and more preferably 20 to 30. By setting the ratio within this range, good flavor development, less irritation, compatibility between the stability and uniformity of the foam and the foam discharge property over time can be achieved, and an oral composition can be obtained. In particular, if the above ratio is less than 10, the stability of the foam decreases, and if it exceeds 70, the uniformity of the foam decreases.

[0017] According to the present invention, an oral composition with high foam stability and uniformity can be obtained. Therefore, for example, even if the amount of foam stabilizing components such as hydroxyethyl cellulose, hydroxypropyl cellulose, hydroxypropyl methyl cellulose, xanthan gum, guar gum, carrageenan, sodium alginate, and thickening silica is reduced, the above effects can be obtained. By reducing the amount of the above components in this way, it is possible to further prevent the pump filter from becoming clogged due to continuous use and the risk of deterioration in usability caused by not being discharged from the container.

[0018] When blending the above foam stabilizing components, the amount is preferably 0.5% or less, more preferably 0.01 - 0.5%, even more preferably less than 0.05%, still more preferably less than 0.02%, particularly preferably less than 0.01% in the composition, and it may also be not blended.

[0019] In the oral composition of the present invention, according to its dosage form, in addition to the above components, other known components can be blended as necessary. Examples of components that can be optionally blended include surfactants other than components (A) and (B), sweeteners, colorants, fragrances, active ingredients, pH adjusters, solvents, etc. Each can be used alone or in combination of two or more, and an appropriate amount can be blended.

[0020] Surfactants other than components (A) and (B) include anionic surfactants, nonionic surfactants, cationic surfactants, etc.

[0021] Examples of anionic surfactants include alkyl sulfates such as sodium lauryl sulfate, acyl sarcosinates, acyl taurates, and acyl amino acid salts. When blending an anionic surfactant, the amount is preferably 1% or less, more preferably 0.8% or less in the composition. By setting it within the above range, the irritation can be further suppressed. Although it is not necessary to blend an anionic surfactant, from the viewpoint of enhancing usability such as ease of application to a toothbrush due to moderate foaming, it is preferably 0.05% or more, more preferably 0.1% or more.

[0022] Examples of nonionic surfactants include sugar fatty acid esters such as sucrose fatty acid esters, sugar alcohol fatty acid esters, sorbitan fatty acid esters, glycerin fatty acid esters, polyglycerin fatty acid esters, polyoxyethylene sorbitan fatty acid esters, polyoxyethylene fatty acid esters such as polyoxyethylene hydrogenated castor oil, and fatty acid alkanolamides. Examples of cationic surfactants include quaternary ammonium salt systems such as alkylammonium type and alkylbenzylammonium salts.

[0023] Examples of sweeteners include saccharin, sodium saccharin, sucralose, stevioside, aspartame, sucrose, fructose, and the like. Examples of colorants include highly safe water-soluble dyes such as Blue No. 1, Green No. 3, Yellow No. 4, and Red No. 105.

[0024] Examples of the fragrance include natural essential oils such as peppermint oil, spearmint oil, eucalyptus oil, wintergreen oil, clove oil, thyme oil, sage oil, cardamom oil, rosemary oil, marjoram oil, lemon oil, nutmeg oil, lavender oil, and para-cresol oil, and fragrance components contained in the above natural essential oils such as L-menthol, carvone, cinnamic aldehyde, orange oil, anethole, 1,8-cineole, methyl salicylate, eugenol, thymol, linalool, limonene, menthone, menthyl acetate, citral, camphor, borneol, pinene, and spirantol. Also included are ethyl acetate, ethyl butyrate, isoamyl acetate, hexanal, methyl anthranilate, ethyl methylphenyl glycidate, benzaldehyde, vanilla, ethyl vanillin, furaneol, maltol, ethyl maltol, gamma / delta-decalactone, gamma / delta-undecalactone, N-ethyl-p-menthane-3-carboxamide, menthyl lactate, ethylene glycol-l-menthyl carbonate, and furthermore, compounded flavors such as apple, banana, strawberry, blueberry, melon, peach, pineapple, grape, muscat, wine, cherry, squash, coffee, brandy, and yogurt formed by combining several fragrance components and natural essential oils (the content is usually 0.00001 to 3% in the composition).

[0025] Examples of the active ingredients include nonionic bactericides such as isopropylmethylphenol; cationic bactericides such as cetylpyridinium chloride and benzalkonium chloride; anionic bactericides such as sodium lauroyl sarcosinate; anti-inflammatory agents such as tranexamic acid and allantoin; enzymes such as dextranase; condensed phosphates such as pyrophosphate, polyphosphate, and hexametaphosphate; fluorine compounds such as sodium fluoride, sodium monofluorophosphate, and stannous fluoride; sodium chloride, vitamins, and plant extracts. The active ingredients can be blended in an effective amount as long as the effects of the present invention are not impaired.

[0026] Examples of the pH adjuster include phthalic acid, phosphoric acid, citric acid, succinic acid, acetic acid, fumaric acid, malic acid, carbonic acid, and salts such as potassium salts, sodium salts, and ammonium salts of these acids, and sodium hydroxide.

[0027] Examples of the solvent include water such as purified water, and lower monohydric alcohols having 1 to 3 carbon atoms such as ethanol. The water content is preferably 70% or more, more preferably 75 to 85% in the composition. By setting the content within the above range, the dischargeability over time is further improved.

[0028] When ethanol is blended in the oral composition of the present invention, the amount thereof is preferably 0.5% or less, more preferably 0.2% or less, still more preferably 0.1% or less, particularly preferably 0.01% or less in the composition, and it may not be blended. By setting the content within the above range, the foam stability is further improved.

[0029] The method for producing the oral composition of the present invention is not particularly limited, and it can be produced by a known method according to the dosage form. For example, the components (A) and (B) and optional components can be blended and produced by an ordinary method.

[0030] [Oral composition] The pH of the oral composition of the present invention is preferably adjusted to 5 to 8 at 25°C. Examples of the pH adjuster in this range include organic acids such as citric acid and lactic acid and their salts; inorganic compounds such as hydrochloric acid, sodium hydroxide, potassium hydroxide, disodium hydrogen phosphate, sodium dihydrogen phosphate, and sodium hydrogen carbonate.

[0031] The viscosity of the oral composition is, for example, preferably a viscosity that is easily discharged from the foam discharge container, and it is preferably a liquid oral composition. For example, the viscosity at 25°C is preferably 0.7 Pa·s or less, more preferably 0.001 to 0.1 Pa·s. Within the above range, the foam stability and foam uniformity are further improved. By setting the viscosity above the above range, the foam shape retention is further improved. The viscosity is a value measured using a BL-type viscometer under the condition of 25°C.

[0032] The oral composition of the present invention is an oral composition that forms foam and is discharged from a container. For example, it is preferably a liquid in the container, and is an oral product having an oral composition and a foam-forming container that houses this oral composition. By being formed of foam, it is easy to rinse even with a light rinse, and is suitable for toothbrushing for persons such as care recipients who have difficulty rinsing.

[0033] [Container] The oral product of the present invention has a foam discharge container that houses an oral composition. The foam discharge container may have a foam formation mechanism and may be of any known structure as long as it can discharge the housed oral composition in a foamed state. As the foam discharge container, a non-aerosol type non-gas normal pressure container having a structure in which the content and air are mixed by applying a pressing force to the content and ejected in a foamed state from the ejection port is preferable. As such a foam discharge container, known squeeze type or pump dispenser type containers can be used. For example, a foam discharge container having the structure described in Japanese Utility Model Publication No. 7-6108, Japanese Unexamined Utility Model Publication No. 7-8251, or Japanese Unexamined Utility Model Publication No. 4-102666 can be used, and various commercially available products may also be used.

[0034] The mesh size is not particularly limited, preferably 100 to 300, more preferably 150 to 250, and even more preferably 100 to 200. The mesh is the number of vertical or horizontal threads per 1 inch (about 25.4 mm), and the number of vertical and horizontal threads is the same. A foam discharge type pump container having a plurality of mesh structures may be used, and their meshes and openings may be combined using the same ones or different ones.

Examples

[0035] Hereinafter, examples and comparative examples will be shown to specifically explain the present invention, but the present invention is not limited to the following examples. In the following examples, % indicates mass % unless otherwise specified. The numbers in parentheses of the polyoxyethylene alkyl ether are the average added mole numbers of the polyoxyethylene chains.

[0036] [Examples, Comparative Examples] Liquid compositions having the compositions shown in Tables 1 to 5 were prepared by a conventional method. The viscosity of the liquid compositions at 25°C was 0.004 to 0.01 Pa·s, and the pH was 5 to 8. The obtained liquid composition was placed in a non-aerosol non-gas normal pressure container (filter: 200 mesh) that mixes the contents with air by applying a pressing pressure to the contents and discharges the mixture in a foamy form from its ejection port, to obtain an oral product. The following evaluations were performed on the obtained oral product.

[0037] [Stability of foam] Stability of the foam when placed on a toothbrush The volume of the foam ejected from the non-aerosol non-gas normal pressure container onto the toothbrush was visually observed and evaluated according to the following criteria. [Evaluation criteria (pass if ○ or above)] ☆: Almost no or no foam collapse was observed, and more than half of the volume was maintained for 30 seconds or more ◎: Some foam collapse was observed, but more than half of the volume was maintained for 30 seconds or more 〇: Some foam collapse was observed, but more than half of the volume was maintained for 5 seconds or more and less than 30 seconds ×: Marked foam collapse was observed, and more than half of the volume could not be maintained for 5 seconds or more

[0038] [Uniformity of foam] Uniformity of the foam when placed on a toothbrush The foam ejected from the non-aerosol non-gas normal pressure container onto the toothbrush was evaluated for its appearance immediately afterwards, according to the following criteria. [Evaluation criteria (pass if ○ or above)] ☆: The bubbles present on the surface of the foam were overall uniform, and the non-uniform part was less than 10% ◎: 10% or more and less than 25% of the foam surface was non-uniform 〇: 25% or more and less than 50% of the foam surface was non-uniform ×: 50% or more of the foam surface was non-uniform

[0039] [Goodness of fragrance development and irritation] Goodness of fragrance development and irritation during use A usage test was conducted by five professional panelists as follows. A foamy oral composition (about 0.2 g) was placed on a toothbrush (product name of Lion Corporation: "Clinica Advantage Hubrush 4-row Compact Regular Type"), and toothbrushing was performed for 3 minutes. The fragrance intensity and irritation during use were scored according to the following scoring criteria. The average score of the five panelists was calculated and evaluated according to the following evaluation criteria. <Scoring Criteria for Fragrance Intensity> 5 points: The fragrance intensity was very good. 4 points: The fragrance intensity was quite good. 3 points: The fragrance intensity was good. 2 points: The fragrance intensity was slightly less than good. 1 point: The fragrance intensity with a very bitter taste was not good. <Scoring Criteria for Irritation During Use> 5 points: No irritation was felt. 4 points: Almost no irritation was felt. 3 points: Slightly no irritation was felt. 2 points: Considerably no irritation was felt. 1 point: Very no irritation was felt.

[0040] [Evaluation Criteria (Pass if 〇 or above)] ☆: The average score of the five panelists is 4.5 points or more. ◎: The average score of the five panelists is 4 points or more. ○: The average score of the five panelists is 3 points or more and less than 4 points. ×: The average score of the five panelists is less than 3 points.

[0041] [Foam Ejection Property after Storage] Foam Ejection Property (Pass if 〇) The content was filled into a non-aerosol non-gas normal pressure container (200 mesh), and the content was discharged from the container every other week for 3 months under the condition of storage at 40°C. The results are shown according to the following evaluation criteria. 〇: It could be discharged from the pump container without problems. ×: Before 3 months passed, it could only be discharged slightly from the container unless the pump was pressed multiple times.

[0042]

Table 1

[0043] [Table 2]

[0044] [Table 3]

[0045] [Table 4]

[0046] [Table 5]

[0047] An oral composition having the following formulation was prepared, and in the same manner as in the above examples, it was contained in a non-aerosol non-gas normal pressure container to obtain an oral product. The obtained oral product was an oral product in which an oral composition that can achieve both good flavor, less irritation, foam stability and uniformity, and foam discharge property over time is discharged in a foamy state from the container.

[0048] [Table 6]

[0049] The raw materials used in the above examples are shown below. The amounts in the table are values in terms of pure content unless otherwise specified. [Table 7]

Claims

Claim 1 (A) Polyoxyethylene alkyl ether and (B) Amphoteric surfactant are contained, the content of the component (A) is 0.5 to 5% by mass, the mass ratio (A) / (B) of the content of the component (A) and the component (B) is 10 to 70, an oral composition, and a foam-forming container containing the oral composition, an oral product in which the oral composition is discharged in a foamy state from the container. Claim 2 The oral product according to claim 1, wherein the content of the anionic surfactant is 1% by mass or less. Claim 3 The oral product according to claim 1, wherein the content of ethanol is 0.5% by mass or less. Claim 4 The oral product according to any one of claims 1 to 3, wherein the water content is 70% by mass or more in the composition.

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