Topical skin composition

Bacteriol stabilizes retinol in skin preparations, addressing instability issues and enhancing anti-aging effects by promoting collagen production.

JP2025094862APending Publication Date: 2025-06-25IKEDA BUSSAN CO
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Patent Information

Application Number
JP2023223608
Authority / Receiving Office
JP · JP
Patent Type
Applications
Current Assignee / Owner
Filing Date
2023-12-13
Publication Date
2025-06-25

AI Technical Summary

Technical Problem

Existing formulations of retinol-based skin preparations face instability due to light and heat, leading to oxidation and unsatisfactory anti-aging effects.

Method used

Incorporation of bacteriol, a terpenophenol compound with retinol-like action, to stabilize retinol and promote collagen production, enhancing anti-aging effects.

Benefits of technology

Bacteriol stabilizes retinol against oxidation and effectively promotes collagen production, improving skin texture and reducing wrinkles and sagging.

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Abstract

To solve the problem in which: there is a strong interest in anti-aging to maintain youthful skin, and ingredients that are effective in preventing and improving wrinkles and sagging are being sought and studied; retinol, a member of the vitamin A group, has anti-wrinkle effects such as collagen production promotion in the skin, resulting in broad use in topical skin compositions such as cosmetic products; however, retinol is unstable to light and heat, raising concerns over possible oxidative degradation when formulated into cosmetic products; in this context, studies on the stabilization of retinol have been conducted and topical skin compositions have been developed, but they have yet to achieve fully satisfactory results.SOLUTION: The present invention provides a novel topical skin composition which incorporates bakuchiol with superior stability and retinol-like effects, thereby promoting collagen production and exerting anti-aging effects.SELECTED DRAWING: Figure 1
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Description

Technical Field

[0001] The present invention relates to an external preparation composition for skin containing bacteriol. Here, the external preparation composition for skin refers to skin care cosmetics such as facial cleansers, lotions, creams, packs, etc., makeup cosmetics such as foundations, lipsticks, mascaras, etc., body care cosmetics such as body soaps, slimming agents, UV care agents, bath agents, antiperspirants, etc., and fragrance cosmetics such as perfumes, eau de colognes, etc., including legally defined cosmetics, quasi-drugs, and pharmaceuticals.

Background Art

[0002] There is a high interest in anti-aging to maintain youthful skin, and ingredients effective for preventing and improving wrinkles and sagging are being sought and studied.

[0003] Various vitamins are used as beauty ingredients in external preparations for skin. Among them, retinol belonging to vitamin A has an anti-wrinkle effect such as promoting collagen production in the skin, and thus is widely used in external preparation compositions for skin such as cosmetics.

[0004] On the other hand, since retinol is unstable to light and heat, there is a concern about the possibility of decomposition by oxidation when formulated in cosmetics and the like.

[0005] In order to stabilize retinol, Patent Document 1 discloses a stabilization method using an organic compound having a specific structure.

Prior Art Documents

Patent Documents

[0006]

Patent Document 1

Disclosure of the Invention

Problems to be Solved by the Invention

[0007] Against the backdrop described above, research has been carried out to stabilize retinol, and topical skin preparations have been developed. However, there are limitations in the formulation, such as the necessity of combination with specific ingredients, and it has not always been satisfactory so far.

Means for Solving the Problems

[0008] The present invention has been made under the above circumstances, and by incorporating bacteriol, which has excellent stability and a retinol-like action, it provides a novel topical skin preparation composition that promotes collagen production and exhibits an anti-aging effect.

[0009] What is shown in claim 1 of the present invention is a topical skin preparation composition characterized by containing bacteriol.

[0010] What is shown in claim 2 of the present invention is the topical skin preparation composition according to claim 1, wherein bacteriol is 0.01 to 25.0% by mass.

[0011] What is shown in claim 3 of the present invention is the topical skin preparation composition according to claim 1 or 2, characterized by containing at least one of vitamin A and its derivatives, and vitamin C and its derivatives.

Effects of the Invention

[0012] Bacteriol of the present invention is a terpenophenol compound having a functionality similar to retinol, induces gene expression, promotes collagen production, and is stable against oxidation by light or the like. Therefore, when incorporated into a topical preparation composition, it exhibits an excellent anti-aging effect.

Brief Description of the Drawings

[0013]

Figure 1

Figure 2

Embodiments for Carrying Out the Invention

[0014] Hereinafter, the present invention will be described in detail. The production method of bakuchiol used in the present invention is not particularly limited, but those extracted and purified from the seeds of Psoralea Corylifolia collected in India can be obtained as the commercially available raw material "Sytenol (registered trademark) A (sithenol A)" of Sytheon Ltd. in the United States.

[0015] The blending amount of bakuchiol of the present invention is 0.01 to 25.0% by mass, preferably 0.1 to 10.0% by mass, in the total amount of the skin external preparation composition using the above-mentioned commercially available raw material. When preparing a normal skin external preparation composition, if it is less than 0.01% by mass, the anti-aging effect by promoting collagen production is not exhibited. Although it is also conceivable to blend up to 25.0% by mass exceeding 10.0% by mass, it is not preferable because the effect corresponding to the blending amount is gradually saturated.

[0016] The effect of the skin external preparation composition of the present invention is to improve wrinkles and sagging by promoting collagen production and maintain youthful skin. Therefore, further effects can be expected when a component that promotes the production of collagen is used in combination with the skin external preparation composition of the present invention. Such components include vitamin A and its derivatives, vitamin C and its derivatives, plant extracts, and the like.

[0017] In addition to the above essential components, other components usually used in skin external preparation compositions such as cosmetics and pharmaceuticals can be blended in the skin external preparation composition of the present invention. Examples of such other components are shown below. The skin external preparation composition of the present invention is produced according to a conventional method by blending one or more of these with the above essential components.

[0018] The following can be cited as oily components. Avocado oil, apricot kernel oil, olive oil, cocoa butter, beef tallow, sesame oil, wheat germ oil, camellia oil, safflower oil, hydrogenated moringa oil, soybean oil, tea seed oil, evening primrose oil, camellia japonica oil, glycolipids, glyceryl tri-fatty acid (C10-18), peppermint leaf oil, palm kernel oil, palm oil, castor oil, sunflower seed oil, Boswellia serrata oil, macadamia seed oil, manuka oil, horse fat, Melia azadirachta seed oil, cottonseed oil, beeswax, (moringa oil / hydrogenated moringa oil) esters, coconut oil, lemon fruit oil, phospholipids, wasabi tree seed oil and other oils and fats. Carnauba wax, candelilla wax, rice bran wax, hydrogenated jojoba oil, sunflower seed wax, mimosa flower wax, partially hydrogenated jojoba oil, jojoba ester, jojoba seed oil, beeswax, lanolin and other waxes. Hydrocarbons such as isoparaffin, hydrogenated polyisobutene, squalane, squalene, ceresin, paraffin, microcrystalline wax, liquid paraffin, petrolatum. Higher fatty acids such as isostearic acid, oleic acid, stearic acid, palmitic acid, hydroxystearic acid, behenic acid, myristic acid, lauric acid, linoleic acid, linolenic acid. Higher alcohols such as isostearyl alcohol, 2-octyldodecanol, oleyl alcohol, cholesterol, stearyl alcohol, cetyl alcohol, cetearyl alcohol, soybean sterol, phytosterols, behenyl alcohol, jojoba alcohol, myristyl alcohol, lanolin alcohol. Alkyl glyceryl ethers such as chimyl alcohol, batyl alcohol. Isostearyl isostearate, phytostearyl isostearate, PG isostearate, cetyl 2-ethylhexanoate, ethoxydiglycol behenate, ethoxydiglycol oleate, hydrolyzed jojoba ester, triethyl citrate, diethylene glycol monoethyl ether, glycol distearate, propylene glycol dino-nanoate, cholesteryl stearate, stearyl stearate, glyceryl tri(caprylate / caprate), triheptanoin, glyceryl tri(2-hexanoate), ethylhexyl palmitate, (behenic acid / oleic acid)(behenyl / oleyl) esters, pentaerythritol tetraester, isopropyl jojoba fatty acid, (jojoba oil / macadamia seed oil) esters, ethyl macadamia nut fatty acid, phytosteryl macadamia nut fatty acid, isopropyl myristate, octyldodecyl myristate, butylene glycol coconut oil fatty acid, propylene glycol laurate, diisostearyl malate and other esters. Silicones such as amino-modified silicone, alkyl-modified silicone, cyclic dimethyl silicone oil, silicone rubber, methylhydrogenpolysiloxane, methylphenylpolysiloxane, methylpolysiloxane.

[0019] Examples of polyhydric alcohols include the following. Polyglycerols such as ethoxydiglycol, octanediol, glycerin, diethylene glycol, diglycerin, dipropylene glycol, 1,3-butylene glycol, propylene glycol, hexanediol, heptanediol, pentanediol, polyethylene glycol, etc.

[0020] Examples of saccharides include the following. Xylitol, sucrose, sorbitol, trehalose, lactose, fructose, maltitol, mannitol, rhamnose, etc.

[0021] Examples of high molecular compounds include the following. Natural polymers such as alkali - producing polysaccharides, alginic acid, casein, curdlan, carrageenan, agar, xanthan gum, chitosan, guar gum, quince seed, collagen, sclerotium gum, gelatin, dextrin, starch, hyaluronic acid, pullulan, pectin, mannan, etc. Natural polymer derivatives such as acetylated hyaluronic acid, ethyl cellulose, cationized guar gum, cationized cellulose, carboxymethyl cellulose, stearoxyhydroxypropylmethyl cellulose, nitrocellulose, hydroxyethyl cellulose, hydroxypropyl cellulose, hydroxypropylmethyl cellulose, polyquaternium - 10, polyquaternium - 67, methyl cellulose, etc. Synthetic polymers such as POE·POP copolymer, alkyl acrylate copolymer, acrylic acid·acrylamide·ethyl acrylate copolymer, acrylic resin alkanolamine, alkyl acrylate·vinyl acetate copolymer, acrylate copolymer Na, carboxyvinyl polymer, highly polymerized polyethylene glycol, high - molecular silicone, silicone resin, (styrene / acrylate) copolymer, vinyl methyl ether·ethyl maleate copolymer, polyacrylamide, sodium polyacrylate, poly(dimethylpiperidinium chloride), polyoxypropylene butyl ether, polyvinyl acetate, polyvinyl alcohol, polyvinyl pyrrolidone, etc.

[0022] The following can be mentioned as surfactants. Anionic surfactants such as acyl N - methyl taurine salt, POE alkyl ether carboxylate, POE alkyl ether sulfate, alkyl ether phosphate ester salt, alkyl benzene sulfonate, alkyl sulfate ester salt, N - acyl amino acid salt, α - olefin sulfonate, higher fatty acid soap, sodium stearoyl glutamate, sodium stearoyl lactylate, etc. Cationic surfactants such as alkyltrimethylammonium chloride, dialkyldimethylammonium chloride, benzalkonium chloride, etc. Amphoteric surfactants such as alkylamidopropyldimethylaminoacetic acid betaine, alkylamidobetaine, 2-alkyl-N-carboxymethyl-N-hydroxyethylimidazolinium betaine, alkyldimethylaminoacetic acid betaine, hydrogenated lecithin, lysophosphatidylcholine, lecithin, etc. Nonionic surfactants such as POE alkylamine · fatty acid amide, POE alkyl ether, POE·POP alkyl ether amine oxide, alkyl glucoside, PEG-6 isostearate, polyglyceryl-6 isostearate, ethoxydiglycol, PEG-8 (caprylic acid / capric acid) glyceryls, (candelilla / jojoba / rice bran) polyglyceryl-3 esters, glycerin fatty acid ester, POE glycerin fatty acid ester, polyglyceryl-3 diisostearate, polyglyceryl-3 dioleate, polyglyceryl-6 distearate, fatty acid alkanolamide, PEG fatty acid ester, PEG-40 hydrogenated castor oil, hydrogenated sunflower seed oil glyceryl esters, hydrogenated sunflower seed oil polyglyceryl-3 esters, PEG-6 stearate, PEG-32 stearate, PEG-75 stearate, glyceryl stearate, polyglyceryl-6 stearate, polyglyceryl-10 stearate, steareth-20, ceteth-20, sorbitan fatty acid ester, POE sorbitan fatty acid ester, POE sorbitol fatty acid ester, triisostearin PEG-6 esters, tribehenin PEG-20 esters, POE castor oil · hydrogenated castor oil, PEG-10 sunflower glyceryls, glyceryl behenate, jojoba wax PEG-80 esters, jojoba wax PEG-120 esters, jojoba oil PEG-150 esters, polyoxyethylene beeswax, polyglyceryl-3 beeswax, polysorbate 80, polyglyceryl-6 polyhydroxystearate, polyglyceryl-6 polyricinoleate, PEG-16 macadamia glyceryls, PEG-8 beeswax, etc.

[0023] Examples of colorants and powders and granules include the following. Inorganic pigments such as iron sulfide, carbon black, iron black oxide, red iron oxide, ultramarine blue, pearl pigments, organic pigments, tar pigments, color materials such as natural pigments. Inorganic powders such as zinc white, alumina, (alumina / iron oxide / titanium oxide / mica) composite, (alumina / titanium oxide / sodium silicate / silica) composite, (alumina / titanium oxide / silica) composite, (alumina / titanium oxide / silica / dimethicone) composite, (alumina / silica) composite, (alumina / silica / talc) composite, mica, mica titanium, kaolin, magnesium aluminum silicate, titanium oxide, (titanium oxide / zirconium oxide / silica) composite, (titanium oxide / silica) composite, (titanium oxide / talc) composite, iron oxide, (iron oxide / titanium oxide / silica / mica) composite, (iron oxide / titanium oxide / mica) composite, (iron oxide / silica) composite, (iron oxide / silica / dimethicone) composite, silica, (silica / polyurethane-15 / mica) composite, (silica / mica) composite, zeolite, talc, hectorite, bentonite, mica, (mica / polyurethane-15) composite, sodium magnesium silicate. Organic powders such as silk powder, cellulose powder, nylon powder, polyethylene powder. Granules such as fatty acid esters, cellulose, natural products, nylon, polyethylene, waxes.

[0024] The following can be cited as components of natural origin. Animal and microbial origin substances such as elastin, hydrolyzed casein, hydrolyzed keratin, hydrolyzed collagen, hydrolyzed silk, hydrolyzed soy protein, hydrolyzed pearl, chitin, chitosan, collagen, sodium chondroitin sulfate, water-soluble collagen, lactose, sodium hyaluronate, whey protein, peptides. Acacia victoria fruit extract, Acacia victoria seed extract, Actinidia deliciosa fruit extract, Acronychia acidula fruit extract, Asparagopsis armata extract, Acerola fruit extract, Anigozanthos manglesii flower extract, Anigozanthos flavidus flower / leaf extract, Anetreaea anisata leaf extract, Araliaceae esculenta extract, Arctium majus root extract, Arnica flower extract, Aloe ferox leaf extract, Aloe vera leaf extract, Italian stone pine leaf / fruit / stem oil, Strawberry fruit extract, Ginkgo leaf extract, Iris root extract, Withania somnifera root extract, Urtica dioica extract, Rhus javanica leaf extract, Eucalyptus radiata extract, Japanese strawberry fruit extract, Magnolia bark extract, Great burdock flower / leaf / stem extract, Barley seed extract, Daikon radish root extract, Odoriko-so extract, Dutch centaury flower extract, Orange fruit extract, Orange fruit water, Chamomile flower extract, Camomile extract, Hydrolyzed wheat protein, Hydrolyzed soybean protein, Triticum aestivum grain extract, Guarana seed extract, Carrot extract, β-carotene, Licorice root extract, Raspberry extract, Raspberry fruit extract, Kiwi extract, Kiwi fruit water, Kigelia africana fruit extract, Japanese centaury extract, Caviar lime extract, Cucumber fruit extract, Euonymus japonicus twig / leaf extract, Krameria bark extract, Guava fruit extract, Cocos nucifera fruit extract, Clara root extract, Cranberry fruit water, Grevillea speciosa flower extract, Grapefruit fruit water, Kunzea pomifera fruit extract, Caper fruit extract, Coconut water, Yeast extract, Rice bran water, Japanese cinquefoil extract, Zanthoxylum piperitum seed extract, Santalum acuminatum fruit extract, Ficus carica extract, Psidium guajava fruit extract, Citrus glauca fruit extract, Ginger water, Populus maximowiczii extract, Thlaspi arvense extract, Japanese cedar bud extract, Prunus mume fruit water, Spirulina platensis extract, Hypericum perforatum leaf / stem extract, European spindle tree seed extract, European dogwood bark extract, European chickweed flower extract, European speedwell extract, European mint extract, Sage leaf extract, Zinnia elegans flower / leaf / stem extract, Centifolia rose flower extract, Lychnis flower / leaf extract, Tasmannia lanceolata fruit extract, Tasmannia lanceolata fruit / leaf extractPlant-derived ingredients such as Davidsonia plumieri fruit extract, dulce extract, tea leaf extract, Camellia sasanqua flower extract, Ajuga reptans extract, tea tree leaf extract, tea tree leaf oil, Terminalia ferdinandiana fruit extract, toki extract, Paeonia lactiflora flower extract, Actinidia arguta extract, tomato fruit / leaf / stem extract, Saururus chinensis root extract, carrot root extract, garlic root extract, pineapple fruit extract, Hibiscus flower extract, Saururus cernuus leaf extract, Saururus trichanthus leaf extract, lotus root water, lotus flower extract, papaya fruit extract, witch hazel extract, witch hazel bark / leaf / twig extract, Luffa acutangula fruit extract, Banksia serrata flower extract, Bambusa arundinacea stem, chrysanthemum flower extract, hinokitiol, Actaea pachypoda extract, Himantalia elongata extract, loquat leaf extract, grape fruit water, grape leaf extract, beech tree sprout extract, plumeria flower extract, Pleione bulbocodioides var. emarginata fruit extract, Luffa cylindrica extract, safflower extract, Cucurbita pepo fruit extract, Persea glomerata seed extract, Lawsonia inermis flower / fruit / leaf extract, Podocarpus elatus fruit extract, Phellinus linteus extract, mango fruit extract, Microcitrus australasica fruit extract, Microcitrus australis fruit extract, Mimosa tenuiflora bark extract, Volvariella volvacea mycelium water, peach leaf extract, Tagetes patula flower extract, vegetable oil, Artemisia vulgaris flower / leaf / stem extract, eucalyptus extract, European white birch bark extract, European beech sprout extract, Ranunculus ficaria extract, Lavandula hybrida oil, labdanum oil, lavender flower / leaf / stem extract, apple fruit extract, apple fruit water, Rumex obtusifolius extract, lemon fruit extract, lemon fruit water, lemon balm leaf, rose water, rosemary leaf extract, Rubus caesius fruit extract, wine extract, etc. Mineral-derived ingredients such as extracts of peridot, malachite, hematite, smithsonite, rhodochrosite, etc.

[0025] The following can be cited as bactericides and preservatives. Benzoic acid and its salts, benzalkonium chloride, isopropylmethylphenol, chlorhexidine, salicylic acid and its salts, zinc pyrithione, sorbic acid and its salts, dehydroacetic acid and its salts, triclosan, 4-terpineol, trichlorocarbanilide, paraoxybenzoic acid esters (methylparaben, ethylparaben, butylparaben, etc.), piroctone olamine, phenoxyethanol, hexachlorophene, methylisothiazolinone, methylchloroisothiazolinone, etc.

[0026] The following can be cited as antioxidants. Sodium bisulfite, vitamin C and its derivatives, vitamin E (tocopherols), butylhydroxyanisole, butylhydroxytoluene, gallic acid esters, etc. Antioxidant aids such as ascorbic acid, citric acid, cephalin, succinic acid, phytic acid, malonic acid, maleic acid, phosphoric acid, etc.

[0027] The following can be cited as metal ion sequestering agents. Edetates, citrates, hydroxyethanediphosphates, phytic acid, malates, etc.

[0028] The following can be cited as ultraviolet ray protectants. Urocanic acid, ethylhexyl triazone, octocrylene, ethylhexyl salicylate, diethylamino hydroxybenzoyl hexyl benzoate, para-aminobenzoic acid, octyl para-dimethylaminobenzoate, bis-ethylhexyloxyphenol methoxyphenyl triazine, 2-hydroxy-4-methoxybenzophenone, 2-hydroxy-4-methoxybenzophenone-5-sulfonic acid, phenylbenzimidazole sulfonic acid, t-butyl methoxydibenzoylmethane, homosalate, polysilicone-15, methylenebisbenzotriazolyl tetramethylbutylphenol, ethylhexyl methoxycinnamate, 2-methylphenyl 4-methoxycinnamate, etc.

[0029] The following can be cited as pH adjusters. Organic and inorganic alkalis such as aminomethylpropanol, aminomethylpropanediol, aqueous ammonia, potassium hydroxide, sodium hydroxide, sodium carbonate, triethanolamine, tromethamine, monoethanolamine, arginine, etc. Organic and inorganic acids such as citric acid, lactic acid, phosphoric acid, malic acid, HCl, etc.

[0030] The following can be cited as various physiologically active components. For the purpose of preventing rough skin, polyhydric alcohols such as glycerin and POE methyl glucoside, saccharides such as trehalose and pullulan. Biopolymers such as elastin, chitin / chitosan, sodium chondroitin sulfate, and sodium hyaluronate. Humectants such as amino acids, sodium lactate, urea, betaine, and PCA-Na. Lipid components such as cholesterol, sphingolipids, ceramides, and phospholipids. Anti-inflammatory agents such as ε-aminocaproic acid, allantoin, lysozyme chloride, guaiazulene, glycyrrhetinic acid derivatives, β-glycyrrhetinic acid, and hydrocortisone. Others such as allantoin and antihistamines. For the purpose of preventing aging, various ultraviolet ray protectants. Antioxidants such as acetylcysteine, oxythiazolidine, ethylbisiminomethylguaiacol manganese chloride, caffeic acid derivatives, carotenoids, glutathione, tannins, vitamins (B2, C, E), hydroxyethylmethylthiopropenamide, flavonoids, ubiquinone, lignans, and lycopene. Cell activators such as α-hydroxy acids. Blood flow accelerators such as γ-oryzanol, vitamin E and its derivatives. For the purpose of whitening, derivatives such as vitamin C, sodium ascorbate, magnesium ascorbyl phosphate, and glucoside ascorbate. Melanin inhibitors such as arbutin, ellagic acid, kojic acid, linoleic acid, linolenic acid, lactic acid, and tranexamic acid. Others such as aminoethylphosphinic acids, sulfur, glutathione, and placenta extract. For the purpose of preventing wrinkles, α-hydroxy acids such as citric acid, glycolic acid, tartaric acid, lactic acid, and malic acid, retinoids (vitamin A derivatives). For the purpose of hair growth, vasodilators such as capronium chloride and benzyl nicotinate. Local stimulants such as capsicum tincture and ginger tincture. Female hormones such as estradiol and ethinyl estradiol. Sebum secretion inhibitors such as pyridoxine hydrochloride. For the purpose of preventing dandruff and itching, climbazole, zinc pyrithione, piroctone olamine, etc. For the purpose of preventing acne, keratolytic and peeling agents such as sulfur, salicylic acid, and resorcinol, and bactericides such as benzalkonium chloride and halocarban. For the purpose of preventing axillary osmidrosis, antiperspirants such as aluminum chloride, chlorhydroxyaluminum, and zinc oxide. For various other physiological activities, vitamins such as pantothenic acid, pantethine, vitamin A and its derivatives, nicotinamide, vitamin B2 and its derivatives, vitamin B6 hydrochloride, vitamin B6 dioctanoate, vitamin B6 tripalmitate, vitamin B12, vitamin B15 and its derivatives, etc., vitamin C such as ascorbic acid, ascorbic acid dipalmitate, ascorbic acid phosphate ester (salt), etc., vitamin D, vitamin E such as α-tocopherol, β-tocopherol, γ-tocopherol, vitamin E acetate, vitamin E nicotinate, etc., and vitamin H. Amino acids and their derivatives such as asparagine, aspartic acid, acetylcitrullamidoarginine, alanine, arginine, carboxyethylaminobutyric acid, glycine, glutamylamidoethylimidazole, glutamidoethylindole, glutamine, serine, taurine, tyrosine, decarboxy carnosine HCl, threonine, valine, histidine, hydroxyproline, pyroglutamylamidoethylindole, phenylalanine, prolinamideethylindole, methylpropylamideacetylmethionine, leucine. Protein-related substances such as acetyltetrapeptide-2, acetylhexapeptide-1, trifluoroacetyltripeptide-2, tripeptide-1, nanopeptide-1, palmitoylpeptide-1. Silanol derivatives such as ascorbylmethylsilanol pectin, aspartic acid methylsilanol hydroxyproline, alginic acid siloxanetriol, glutamic acid silanetriol, salicylic acid silandiol, dioleyltocopherylmethylsilanol, dimethyloxobenzodioxasilane, silanetriol, silanetriol alginate, silanetriol trehalose ether, hyaluronic acid dimethylsilanol, polysilicone-3, methylsilanol acetyltyrosine, methylsilanol lactic acid Na, mannuronic acid acephillin methylsilanol, mannuronic acid methylsilanol, lysine silanetriol, PCA copper methylsilanol. Slimming-related components such as caffeine, extract of dulce, etc.

[0031] The dosage form of the topical composition for skin of the present invention can take forms commonly used as topical compositions for skin, such as liquid, emulsion, cream, gel, mist, aerosol foam, solid, powder dispersion system, etc.

Examples

[0032] Next, the present invention will be described more specifically with reference to examples. It should be noted that the present invention is not limited to these examples only. The blending amounts are shown in mass% unless otherwise specified.

[0033] Example 1 The formulation of a clear beauty liquid is exemplified in Table 1.

Table 1

[0034] Example 2 The formulation of an anti-aging cream (W / O) is exemplified in Table 2.

Table 2

[0035] Example 3 The formulation of an anti-aging cream (O / W) is exemplified in Table 3.

Table 3

[0036] Example 4 The formulation of a moisturizing gel is exemplified in Table 4.

Table 4

[0037] Example 5 The formulation of an oil beauty liquid is exemplified in Table 5.

Table 5

[0038] Example 6 illustrates the formulation of a cleansing cream in Table 6.

Table 6

Industrial Applicability

[0039] The present invention can be widely used in the industries of manufacturing and selling external preparation compositions such as cosmetics, quasi-drugs, and pharmaceuticals.

Claims

Claim 1 An external preparation composition for skin, characterized by containing bactiol. Claim 2 The external preparation composition for skin according to claim 1, wherein bactiol is 0.01 to 25.0% by mass. Claim 3 The external preparation composition for skin according to claim 1 or 2, characterized by containing at least one of vitamin A and its derivatives, and vitamin C and its derivatives.

Citation Information

Patent Citations

  • Method for stabilizing vitamin a and its derivatives

    JP2012012347A