Cosmetic

Abstract

To provide a cosmetic that includes a skin-aging preventive component while achieving superior usability.SOLUTION: The present invention relates to an oil-in-water cosmetic that contains the following components (A) and (B): (A) 0.2-1.0 mass% of dipotassium glycyrrhizate relative to the whole cosmetic, and (B) a polyethylene glycol fatty acid ester.SELECTED DRAWING: None

Description

[Technical Field]

[0001] The present invention relates to cosmetics, particularly to oil-in-water cosmetics. [Background technology]

[0002] It is known that aging symptoms such as wrinkles are caused by aging, ultraviolet rays, etc. Such aging symptoms can have a significant impact on the impression of one's appearance, etc., and therefore there is a high demand for cosmetics containing ingredients that improve aging symptoms such as wrinkles.

[0003] Dipotassium glycyrrhizinate is known as one of the components that has an anti-wrinkle effect (Patent Document 1), but cosmetics containing dipotassium glycyrrhizinate may cause a sticky feeling. [Prior art documents] [Patent documents]

[0004] [Patent Document 1] Patent Publication No. 2019-108278 Summary of the Invention [Problem to be solved by the invention]

[0005] In view of the above circumstances, an object of the present invention is to provide a cosmetic that contains dipotassium glycyrrhizinate but has a reduced sticky feeling. [Means for solving the problem]

[0006] The present inventors conducted research to solve the above problems and discovered that a cosmetic composition that meets the above problems can be produced by using a combination of a specific amount of dipotassium glycyrrhizinate and a specific surfactant, and thus completed the present invention. That is, the gist of the present invention relates to the following.

[0007] [1] The following components (A) and (B): (A) 0.2 to 1.0% by mass of dipotassium glycyrrhizinate relative to the total amount of the cosmetic; (B) polyethylene glycol fatty acid ester, An oil-in-water cosmetic comprising: [2] The oil-in-water cosmetic according to [1], wherein the polyethylene glycol fatty acid ester of component (B) comprises polyethylene glycol stearate and / or polyethylene glycol distearate. [3] The oil-in-water cosmetic according to [1] or [2], wherein the polyethylene glycol fatty acid ester of component (B) comprises one or more selected from PEG-25 stearate, PEG-100 stearate, and PEG-150 stearate. [4] The oil-in-water cosmetic according to any one of [1] to [3], containing 0.05 to 15% by mass of component (B) relative to the total amount of the cosmetic. [5] The oil-in-water cosmetic according to any one of [1] to [4], wherein the mass ratio of the contents of components (A) and (B) ((B) / (A)) is 0.05 to 60. [6] The following components (A) and (B): (A) 0.2 to 1.0% by mass of dipotassium glycyrrhizinate relative to the total amount of the cosmetic; (B) polyethylene glycol fatty acid ester, A method for producing an oil-in-water cosmetic, comprising the step of blending [Effects of the Invention]

[0008] According to the present invention, it is possible to provide a cosmetic preparation that contains dipotassium glycyrrhizinate as a skin aging prevention ingredient, yet has a reduced sticky feeling. Furthermore, the cosmetic of the present invention suppresses squeaky and dry sensations and is also excellent in suppressing crystal precipitation. DETAILED DESCRIPTION OF THE INVENTION

[0009] The present invention will be described below. <Cosmetics> One aspect of the present invention is The present invention relates to an oil-in-water cosmetic (hereinafter sometimes referred to as "the cosmetic of the present invention") containing the following components (A) and (B): (A) 0.2 to 1.0% by mass of dipotassium glycyrrhizinate relative to the total amount of the cosmetic; (B) Polyethylene glycol fatty acid ester.

[0010] The present inventors have conducted various investigations in search of a cosmetic composition that contains dipotassium glycyrrhizinate as a skin aging prevention ingredient, yet has a reduced sticky feeling.

[0011] Among these, the present inventors have succeeded in creating a cosmetic composition that contains dipotassium glycyrrhizinate in an amount of 0.2 to 1.0% by mass based on the total cosmetic composition, in combination with a surfactant polyethylene glycol fatty acid ester, and that does not leave a sticky feeling after application and has an excellent feel when used. Furthermore, they have discovered that such a cosmetic composition has an excellent feel when used in terms of suppressing the squeaky feeling and dryness, and also has excellent suppression of crystal precipitation and formulation stability. Based on these findings, the present invention has been completed.

[0012] <Component (A) Dipotassium Glycyrrhizinate> The cosmetic preparation of the present invention contains dipotassium glycyrrhizinate as component (A). The dipotassium glycyrrhizinate used in the present invention may be an artificially synthesized product or may be obtained from a natural product such as a plant, etc. Furthermore, dipotassium glycyrrhizinate may be provided in the form of a plant extract containing it.

[0013] Dipotassium glycyrrhizinate may be a commercially available product, or may be extracted from, for example, a plant of the genus Glycyrrhiza of the Leguminosae family. The species include Spanish licorice (G. glabra), Ural licorice (G. uralensis), Examples include G. inflata.

[0014] The method for extracting dipotassium glycyrrhizinate from a plant of the genus Glycyrrhiza in the family Leguminosae is not particularly limited, and can be a conventional extraction method, i.e., adding 1 to 20 times the amount of water or a lower alcohol such as ethanol as a solvent to the plant body or a processed product thereof, stirring as desired, and immersing the plant body or a processed product thereof for several days at room temperature or for several hours at a temperature near the boiling point, removing insoluble matter by filtration or the like, and then, if desired, removing the solvent by vacuum distillation or the like, and, in some cases, purifying and fractionating the product by column chromatography or the like, and then using the product. A preferred example of a plant part for preparing a plant extract is the rhizome.

[0015] In the cosmetic of the present invention, the content of component (A) is 0.2 to 1.0% by mass relative to the total cosmetic. This range allows for excellent effects to be achieved in the present invention. Furthermore, the content of component (A) may be 0.2% by mass or more, 0.3% by mass or more, or 0.5% by mass or more relative to the total cosmetic, and may be 1.0% by mass or less, 0.8% by mass or less, or 0.7% by mass or less, or any combination thereof that is not contradictory. Furthermore, the content of component (A) may be 0.2 to 1.0% by mass, 0.3 to 0.8% by mass, or 0.5 to 0.7% by mass relative to the total cosmetic.

[0016] When the content of component (A) is 0.2% by mass or more, sufficient anti-aging effects for skin can be obtained, and when it is 1.0% by mass or less, smooth spreading is achieved, it is easy to form a uniform cosmetic film, and it is less likely to feel sticky. Furthermore, by using it in this range, it is easy to obtain a better feel when used, such as no squeaky feeling or dry feeling, and it is easy to obtain formulation stability.

[0017] <Component (B) Polyethylene glycol fatty acid ester> The cosmetic of the present invention contains a polyethylene glycol fatty acid ester as a surfactant as component (B). There are no particular limitations on the polyethylene glycol fatty acid ester, so long as it is one that is normally contained in cosmetics, and commercially available products can be used.

[0018] Polyethylene glycol fatty acid esters are surfactants in which polyethylene glycol is ester-bonded to a fatty acid. The number of moles of ethylene oxide added in the polyethylene glycol fatty acid ester is not particularly limited, but may be, for example, 20 to 150, or 25 to 150, etc. The fatty acids constituting the polyethylene glycol fatty acid ester may be either linear or branched, and may be either saturated or unsaturated. Non-limiting examples include esters of polyethylene glycol with fatty acids having 12 to 18 carbon atoms, such as lauric acid, myristic acid, palmitic acid, stearic acid, isostearic acid, and oleic acid. The number of fatty acids ester-bonded to polyethylene glycol in one polyethylene glycol fatty acid ester molecule is, for example, 1 or 2 (i.e., monoester or diester), preferably 1 (i.e., monoester). More specific examples of polyethylene glycol fatty acid esters include mono-fatty acid polyethylene glycols such as polyethylene glycol (mono)laurate, polyethylene glycol (mono)myristylate, polyethylene glycol (mono)palmitate, polyethylene glycol (mono)stearate, polyethylene glycol (mono)isostearate, and polyethylene glycol (mono)oleate; and di-fatty acid polyethylene glycols such as polyethylene glycol dilaurate, polyethylene glycol dimyristylate, polyethylene glycol dipalmitate, polyethylene glycol distearate, polyethylene glycol diisostearate, and polyethylene glycol dioleate. One or more of these polyethylene glycol fatty acid esters can be contained. Among these, polyethylene glycol stearate and / or polyethylene glycol distearate are preferred, and one or more selected from PEG-25 stearate, PEG-100 stearate, and PEG-150 stearate are more preferred. The HLB value of the polyethylene glycol fatty acid ester is not particularly limited, but is preferably 12 to 20 or 14 to 20. In this specification, the HLB value refers to a value calculated using the Griffin formula. The polyethylene glycol fatty acid ester is not limited, but commercially available products such as NIKKOL MYS-25V (manufactured by Nikko Chemicals Co., Ltd.) (HLB=15.0) as PEG-25 stearate, EMALEX 8100R (manufactured by Nippon Emulsion Co., Ltd.) (HLB=17) as PEG-100 stearate, and EMANON 3199VB (manufactured by Kao Corporation) (HLB=19.4) as PEG-150 stearate can be used.

[0019] In the cosmetic of the present invention, the content of component (B) is not limited, but may be, for example, 0.05% by mass or more, 0.1% by mass or more, 0.2% by mass or more, or 0.5% by mass or more, and 15% by mass or less, 6% by mass or less, 4% by mass or less, or 2% by mass or less, based on the total amount of the cosmetic. The content of component (B) may be 0.05 to 15 mass%, 0.1 to 6 mass%, 0.2 to 4 mass%, or 0.5 to 2 mass% of the total cosmetic preparation. By using the component in this range, the cosmetic composition will feel less sticky after application, and it is also easier to obtain a better feel when used, such as no squeaky or dry feeling, and formulation stability.

[0020] Furthermore, the mass ratio of component (A) to component (B) in the present invention, expressed as the mass ratio (B) / (A) of component (B) to component (A), is not particularly limited from the viewpoint of usability, formulation stability, etc., and may be, for example, 0.05 to 60, 0.1 to 25, 0.5 to 10, or 1 to 2.

[0021] The formulation of the cosmetic of the present invention is not particularly limited to an aqueous formulation or an emulsion type, but an emulsion type is preferred, and may be a water-in-oil type or an oil-in-water type, with an oil-in-water emulsion type being particularly preferred. The oil-in-water emulsion type is not particularly limited as long as the outermost phase is an aqueous phase, and may be an O / W type, a W / O / W type, an (O1+O2) / W type, or the like.

[0022] When the cosmetic of the present invention is in the form of an emulsion, it contains an aqueous phase component and an oil phase component. The cosmetic of the present invention contains water as an aqueous phase component. The aqueous phase component may be any component other than water that dissolves in water at 25 to 90° C. The oil phase component is not limited to oils and generally includes powders, etc., and may be any component that undergoes phase separation from water after being suspended in water at 25 to 90° C. and left to stand for 1 hour. When the cosmetic of the present invention is in the form of an emulsion, the mass ratio of the content of the aqueous phase component to the oil phase component is not particularly limited, but is preferably 99:1 to 50:50, more preferably 95:5 to 70:40.

[0023] The cosmetic of the present invention can be used in the form of cosmetics including quasi-drugs. Specific examples of the cosmetic include skin care cosmetics such as lotions, emulsions, and creams, makeup cosmetics such as makeup bases and foundations, and sunscreen cosmetics such as sunscreen emulsions and sunscreen creams. Furthermore, the cosmetic can be in a variety of forms, including liquid, emulsion, and cream.

[0024] ≪Optional ingredients≫ Furthermore, the cosmetic of the present invention may contain optional ingredients other than the above ingredients, as long as the effects of the cosmetic are not impaired. The optional components are not particularly limited, and any known components used in the field of external skin preparations such as cosmetics can be used. One or a combination of two or more optional components can be used in the present invention.

[0025] Examples of such optional components include oils, powders, alcohols, ethers, moisturizers, surfactants, ultraviolet absorbers, ultraviolet scattering agents, sequestering agents, pearlescent agents, amino acids, organic amines, organic salts, inorganic salts, polymer emulsions, pH adjusters, vitamins, antioxidants, preservatives, water-soluble polymers, fragrances, and various active ingredients.

[0026] Examples of oils include silicone oils, polar oils, natural oils, hydrocarbons, and higher fatty acids.

[0027] Silicone oils include dimethylpolysiloxane (dimethicone), cyclopentasiloxane, decamethylcyclopentasiloxane, caprylyl methicone, trimethylsiloxysilicate, and diphenylsiloxyphenyl trimethicone.

[0028] Polar oils include synthetic ester oils such as isopropyl myristate, cetyl octanoate, octyldodecyl myristate, isopropyl palmitate, butyl stearate, hexyl laurate, myristyl myristate, decyl oleate, hexyldecyl dimethyloctanoate, cetyl lactate, myristyl lactate, lanolin acetate, isocetyl stearate, isocetyl isostearate, cholesteryl 12-hydroxystearate, ethylene glycol di-2-ethylhexylate, dipentaerythritol fatty acid esters, N-alkyl glycol monoisostearate, neopentyl glycol dicaprate, diisostearyl malate, glyceryl di-2-heptylundecanoate, trimethylolpropane tri-2-ethylhexylate, trimethylolpropane triisostearate, pentaneerythritol tetra-2-ethylhexylate, Glyceryl 2-ethylhexanoate, trimethylolpropane triisostearate, cetyl 2-ethylhexanoate, 2-ethylhexyl palmitate, glyceryl trimyristate, tri-2-heptylundecanoic acid glyceride, castor oil fatty acid methyl ester, oleic acid oil, cetostearyl alcohol, acetoglyceride, 2-heptylundecyl palmitate, diisobutyl adipate, N-lauroy Examples of suitable esters include 2-octyldodecyl-L-glutamate, di-2-heptylundecyl adipate, ethyl laurate, di-2-ethylhexyl sebacate, 2-hexyldecyl myristate, 2-hexyldecyl palmitate, 2-hexyldecyl adipate, diisopropyl sebacate, 2-ethylhexyl succinate, isononyl isononanoate, ethyl acetate, butyl acetate, amyl acetate, and triethyl citrate.

[0029] Examples of natural oils include avocado oil, camellia oil, turtle oil, macadamia nut oil, corn oil, mink oil, olive oil, rapeseed oil, egg yolk oil, sesame oil, persic oil, wheat germ oil, camellia oil, castor oil, linseed oil, safflower oil, cottonseed oil, perilla oil, soybean oil, peanut oil, tea seed oil, Japanese kaya oil, rice bran oil, Chinese tung oil, Japanese tung oil, jojoba oil, germ oil, sunflower oil, triglycerin, glyceryl trioctanoate, and glyceryl triisopalmitate.

[0030] Examples of hydrocarbon oils include isododecane, isohexadecane, squalane, hydrogenated poly(C6-12)olefin, and hydrogenated polyisobutene.

[0031] Examples of higher fatty acids include lauric acid, myristic acid, palmitic acid, stearic acid, behenic acid, 12-hydroxystearic acid, undecylenic acid, and tall acid.

[0032] The powder may be spherical, needle-like, plate-like, or the like, and its shape is not particularly limited. Examples of the powder include inorganic white pigments (e.g., titanium dioxide, zinc oxide, etc.); inorganic red pigments (e.g., iron oxide (red iron), iron titanate, etc.); inorganic brown pigments (e.g., γ-iron oxide, etc.); inorganic yellow pigments (e.g., yellow iron oxide, ochre, etc.); inorganic black pigments (e.g., black iron oxide, low-order titanium oxide, etc.); inorganic purple pigments (e.g., mango violet, cobalt violet, etc.); inorganic green pigments (e.g., chromium oxide, hydroxide chromium chloride, cobalt titanate, etc.); inorganic blue pigments (e.g., ultramarine, iron blue, etc.); pearl pigments (e.g., titanium dioxide-coated mica, titanium dioxide-coated bismuth oxychloride, titanium dioxide-coated talc, colored titanium dioxide-coated mica, bismuth oxychloride, fish scale foil, etc.); metal powder pigments (e.g., aluminum powder, copper powder, etc.); organic pigments such as zirconium, barium, or aluminum lake (e.g., Red 201, Red 202, Red 204, Red Organic pigments such as Color No. 205, Red No. 220, Red No. 226, Red No. 228, Red No. 405, Orange No. 203, Orange No. 204, Yellow No. 205, Yellow No. 401, and Blue No. 404, Red No. 3, Red No. 104, Red No. 106, Red No. 227, Red No. 230, Red No. 401, Red No. 505, Orange No. 205, Yellow No. 4, Yellow No. 5, Yellow 202, Yellow No. 203, Green No. 3, and Blue No. 1; natural pigments (e.g., chlorophyll, beta-carotene, etc.); inorganic powders (e.g., talc, kaolin, Mica, sericite (sericite), muscovite, phlogopite, synthetic mica, lepidolite, biotite, vermiculite, magnesium carbonate, calcium carbonate, aluminum silicate, barium silicate, calcium silicate, magnesium silicate, strontium silicate, metal tungstate, magnesium, silica, alumina, zeolite, barium sulfate, calcined calcium sulfate (calcined gypsum), calcium phosphate, fluorapatite, hydroxyapatite, ceramic powder, boron nitride, etc.);Examples of suitable organic powders include polyamide resin powder (nylon powder), polyethylene powder, poly(methyl meth)acrylate powder, polystyrene powder, styrene-acrylic acid copolymer resin powder, silicone resin powder, benzoguanamine resin powder, polytetrafluoroethylene powder, cellulose powder, and silicone composite spherical powders (e.g., vinyl dimethicone / methicone silsesquioxane crosspolymer, diphenyl dimethicone / vinyl diphenyl dimethicone / silsesquioxane crosspolymer, polysilicone-22, polysilicone-1 crosspolymer, etc.); metal soaps (e.g., zinc myristate, calcium palmitate, aluminum stearate); and organically modified clay minerals (e.g., organically modified bentonite, organically modified hectorite, etc.).

[0033] Examples of alcohols include monohydric alcohols such as ethanol, isopropanol, cetanol, batyl alcohol, behenyl alcohol, palmitoleic alcohol, heptadecanol, 1-heptadecanol, stearyl alcohol, isostearyl alcohol, elaidyl alcohol, oleyl alcohol, linoleyl alcohol, elaidolinoleyl alcohol, linolenyl alcohol, elaidolinolenyl alcohol, ricinoleyl alcohol, nonadecyl alcohol, arachidyl alcohol, heneicosanol, and erucyl alcohol; ethylene glycol, 1,3-butylene glycol, trimethylene glycol, 1,2- Dihydric alcohols such as butylene glycol, propylene glycol, dipropylene glycol, propanediol, 1,2-pentanediol, 3-methyl-1,3-butanediol, tetramethylene glycol, 2,3-butylene glycol, pentamethylene glycol, 2-butene-1,4-diol, hexylene glycol, and octylene glycol; trihydric alcohols such as trimethylolpropane; tetrahydric alcohols such as pentaerythritol; pentahydric alcohols such as xylitol; polyhydric alcohol polymers such as triglycerin, tetraglycerin, and polyglycerin; sugar alcohols such as starch-decomposed sugar-reduced alcohols; polyglycerin; alcohol alkyl ethers such as ethylene glycol monomethyl ether, ethylene glycol monoethyl ether, ethylene glycol monobutyl ether, ethylene glycol monophenyl ether, ethylene glycol monohexyl ether, ethylene glycol mono-2-methylhexyl ether, ethylene glycol isoamyl ether, ethylene glycol benzyl ether, and ethylene glycol isopropyl ether; alcohol alkyl ethers such as diethylene glycol monomethyl ether, diethylene glycol monoethyl ether, diethylene glycol monobutyl ether, triethylene glycol monomethyl ether, triethylene glycol monoethyl ether, propylene glycol monomethyl ether, propylene glycol monoethyl ether, propylene glycol monobutyl ether, propylene glycol isopropyl ether, dipropylene glycol methyl ether, dipropylene glycol ethyl ether, and dipropylene glycol butyl ether; glycerin monoalkyl ethers such as xyl alcohol, selachyl alcohol, and batyl alcohol; Alcohol polymers such as diethylene glycol, triethylene glycol, polypropylene glycol, tetraethylene glycol, and polyethylene glycol; Glysolid;Tetrahydrofurfuryl alcohol;POE-tetrahydrofurfuryl alcohol;POP-butyl ether;POP·POE-butyl ether;Tripoly Examples include oxypropylene glycerin ether; POP-glycerin ether; POP-glycerin ether phosphate; POP·POE-pentaneerythritol ether, etc.

[0034] Examples of ethers include those corresponding to the above alcohols, as well as ethylene glycol dimethyl ether, ethylene glycol diethyl ether, ethylene glycol dibutyl ether, diethylene glycol dimethyl ether, diethylene glycol diethyl ether, diethylene glycol methyl ethyl ether, ethylene glycol monomethyl ether acetate, ethylene glycol monoethyl ether acetate, ethylene glycol monobutyl ether acetate, ethylene glycol monophenyl ether acetate, ethylene glycol diadipate, ethylene glycol disuccinate, diethylene glycol monoethyl ether acetate, diethylene glycol monobutyl ether acetate, propylene glycol monomethyl ether acetate, propylene glycol monoethyl ether acetate, propylene glycol monopropyl ether acetate, and propylene glycol monophenyl ether acetate.

[0035] Examples of moisturizing agents include chondroitin sulfate and its salts, hyaluronic acid and its salts, mucoitin sulfate, caronic acid, atelocollagen, cholesteryl-12-hydroxystearate, sodium lactate, dl-pyrrolidone carboxylate, short-chain soluble collagen, diglycerin (EO)PO adduct, Rosa robur extract, yarrow extract, and melilot extract.

[0036] Surfactants include anionic surfactants, cationic surfactants, amphoteric surfactants, and nonionic surfactants.

[0037] Examples of anionic surfactants include acyl lactates (e.g., sodium stearoyl lactylate, sodium lauroyl lactylate, etc.); fatty acid soaps (e.g., sodium laurate, sodium palmitate, etc.); higher alkyl sulfates (e.g., sodium lauryl sulfate, potassium lauryl sulfate, etc.); alkyl ether sulfates (e.g., POE triethanolamine lauryl sulfate, POE sodium lauryl sulfate, etc.); N-acyl sarcosinates (e.g., sodium lauroyl sarcosinate, etc.); higher fatty acid amide sulfonates (e.g., sodium N-myristoyl-N-methyl taurate, sodium coconut oil fatty acid methyl tauride, sodium lauryl methyl tauride, etc.); phosphate ester salts (sodium POE oleyl ether phosphate, sodium POE stearyl ether phosphate, etc.); sulfosuccinates (e.g., sodium di-2-ethylhexyl sulfosuccinate, sodium monolauroyl monoethanolamide polyoxyethylene sulfosuccinate, sodium lauryl methyl tauride, etc.); sodium uryl polypropylene glycol sulfosuccinate, etc.); alkylbenzene sulfonates (e.g., sodium linear dodecylbenzene sulfonate, triethanolamine linear dodecylbenzene sulfonate, linear dodecylbenzene sulfonic acid, etc.); higher fatty acid ester sulfate salts (e.g., sodium hydrogenated coconut oil fatty acid glycerin sulfate, etc.); N-acyl glutamates (e.g., monosodium N-lauroyl glutamate, disodium N-stearoyl glutamate, monosodium N-myristoyl-L-glutamate, etc.); sulfated oils (e.g., turmeric oil, etc.); POE alkyl ether carboxylic acids; POE alkyl allyl ether carboxylate salts; α-olefin sulfonates; higher fatty acid ester sulfonates; secondary alcohol sulfate salts; higher fatty acid alkylolamide sulfate salts; sodium lauroyl monoethanolamide succinate; ditriethanolamine N-palmitoyl aspartate; sodium caseinate, etc.

[0038] Examples of cationic surfactants include alkyltrimethylammonium salts (e.g., stearyltrimethylammonium chloride, lauryltrimethylammonium chloride, etc.); alkylpyridinium salts (e.g., cetylpyridinium chloride, etc.); distearyldimethylammonium chloride dialkyldimethylammonium salts; poly(N,N'-dimethyl-3,5-methylenepiperidinium chloride); alkyl quaternary ammonium salts; alkyldimethylbenzylammonium salts; alkylisoquinolinium salts; dialkylmorphonium salts; POE alkylamines; alkylamine salts; polyamine fatty acid derivatives; amyl alcohol fatty acid derivatives; benzalkonium chloride; benzethonium chloride, etc.

[0039] Examples of amphoteric surfactants include imidazoline-based amphoteric surfactants (e.g., 2-undecyl-N,N,N-(hydroxyethylcarboxymethyl)-2-imidazoline sodium, 2-cocoyl-2-imidazolinium hydroxide-1-carboxyethyloxy disodium salt, etc.); betaine-based surfactants (e.g., 2-heptadecyl-N-carboxymethyl-N-hydroxyethylimidazolinium betaine, lauryldimethylaminoacetic acid betaine, alkyl betaine, amido betaine, sulfobetaine, etc.).

[0040] Examples of nonionic surfactants include polyether-modified silicones (e.g., polyethylene glycol-10 dimethicone, polyethylene glycol-12 dimethicone, PEG-9 polymethylsiloxyethyl dimethicone, lauryl PEG-9 polydimethylsiloxyethyl dimethicone, PEG-9 polydimethylsiloxyethyl dimethicone, etc.); polyglycerin-modified silicones (e.g., polyglyceryl-3 disiloxane dimethicone, polyglyceryl-3 polydimethylsiloxyethyl dimethicone, etc.); sorbitan fatty acid esters (e.g., sorbitan monooleate, sorbitan monostearate, sorbitan monoisostearate, sorbitan monolaurate, sorbitan monopalmitate, sorbitan monostearate, sorbitan monoisostearate, sorbitan monolaurate, sorbitan monopalmitate, sorbitan monoisostearate ... sorbitan stearate, sorbitan sesquioleate, sorbitan trioleate, diglycerol sorbitan penta-2-ethylhexylate, diglycerol sorbitan tetra-2-ethylhexylate, etc.); glycerin fatty acids (e.g., glycerin monocottonseed oil fatty acid, glycerin monoerucate, glycerin sesquioleate, glycerin monostearate, glycerin α,α'-oleic acid pyroglutamate, glycerin monostearate malate, etc.); propylene glycol fatty acid esters (e.g., propylene glycol monostearate, etc.); POE castor oil / hydrogenated castor oil derivatives (POE castor oil, POE hydrogenated castor oil, etc.); and non-hydrophilic nonionic surfactants such as glycerin alkyl ethers.Also, polyglycerol fatty acid esters (e.g., polyglyceryl monooleate, polyglyceryl monostearate, etc.); POE sorbitan fatty acid esters (e.g., POE sorbitan monooleate, POE sorbitan monostearate, POE sorbitan tetraoleate, etc.); POE sorbit fatty acid esters (e.g., POE sorbit monolaurate, POE sorbit monooleate, POE sorbit pentaoleate, POE sorbit monostearate, etc.); POE glycerin fatty acid esters (e.g., POE glycerin monostearate, POE glycerin monoisostearate, POE glycerin triisostearate, etc.) POE monooleate, etc.); POE alkyl ethers (e.g., POE lauryl ether, POE oleyl ether, POE stearyl ether, POE-behenyl ether, POE-2-octyldodecyl ether, POE cholestanol ether, etc.); POE alkyl phenyl ethers (e.g., POE nonylphenyl ether, etc.); Pluronic types (e.g., Pluronic (registered trademark), etc.); POE·POP alkyl ethers (e.g., POE·POP cetyl ether, POE·POP-2-decyltetradecyl ether, POE·POP monobutyl ether, POE·POP hydrogenated lanolin, POE·POP glycerin ether, etc.); tetra Other examples of hydrophilic nonionic surfactants include POE-tetra-POP ethylenediamine condensates (e.g., Tetronic); POE castor oil hydrogenated castor oil derivatives (e.g., POE castor oil, POE hydrogenated castor oil, POE hydrogenated castor oil monoisostearate, POE hydrogenated castor oil triisostearate, POE hydrogenated castor oil monopyroglutamic acid monoisostearate diester, POE hydrogenated castor oil maleic acid); POE beeswax / lanolin derivatives (e.g., POE sorbitol beeswax); alkanolamides (e.g., coconut oil fatty acid diethanolamide, lauric acid monoethanolamide, fatty acid isopropanolamide); POE propylene glycol fatty acid esters; POE alkylamines; POE fatty acid amides; sucrose fatty acid esters; alkyl glucosides; alkylethoxydimethylamine oxide; and trioleyl phosphate.

[0041] Examples of ultraviolet absorbers include cinnamic acid-based ultraviolet absorbers such as 2-ethylhexyl paramethoxycinnamate, isopropyl paramethoxycinnamate, diethanolamine paramethoxyhydrocinnamate, glyceryl di-paramethoxycinnamate-mono-2-ethylhexanoate, octyl methoxycinnamate, and methyl diisopropylcinnamate; 2-hydroxy-4-methoxybenzophenone, 2-hydroxy-4-methoxybenzophenone-5-sulfuric acid, sodium 2-hydroxy-4-methoxybenzophenone-5-sulfate; and 2,4- Benzophenone-based ultraviolet absorbers such as dihydroxybenzophenone, 2,2'-dihydroxy-4,4'-dimethoxybenzophenone, 2,2'-dihydroxy-4-methoxybenzophenone, 2,2',4,4'-tetrahydroxybenzophenone, and 2-hydroxy-4-n-octoxybenzophenone, para-aminobenzoic acid, ethyl para-aminobenzoate, butyl para-aminobenzoate, 2-ethylhexyl para-dimethylaminobenzoate, glyceryl para-aminobenzoate, octyl para-dimethylaminobenzoate, and para-aminobenzoic acid. Benzoic acid-based UV absorbers such as amyl aminobenzoate, dimethylaminohydroxybenzoyl hexyl benzoate, and diethylaminohydroxybenzoyl hexyl benzoate; salicylic acid-based UV absorbers such as 2-ethylhexyl salicylate, triethanolamine salicylate, homomenthyl salicylate, dipropylene glycol salicylate, methyl salicylate, ethylene glycol salicylate, phenyl salicylate, amyl salicylate, benzyl salicylate, isopropyl benzyl salicylate, and potassium salicylate; 4-t Dibenzoylmethane ultraviolet absorbers such as ert-butyl-4'-methoxydibenzoylmethane, 4-isopropyldibenzoylmethane, 4-methoxydibenzoylmethane, and 4-tert-butyl-4'-hydroxydibenzoylmethane, menthyl-O-aminobenzoate, 2-phenyl-benzimidazole-5-sulfuric acid, 2-phenyl-5-methylbenzoxazole, 3-(4-methylbenzylidene)camphor, 2-ethylhexyl-2-cyano-3,3-diphenylacrylate, and 2-ethyl-2-cyano-3,Examples of such ultraviolet absorbers include anthranilic acid-based ultraviolet absorbers such as 3'-diphenylacrylate, 2-(2'-hydroxy-5-methylphenyl)benzotriazole, and menthyl anthranilate; urocanic acid-based ultraviolet absorbers such as ethyl urocanate; and triazine-based ultraviolet absorbers such as bisethylhexyloxyphenol methoxyphenyl triazine and ethylhexyl triazone.

[0042] Examples of ultraviolet scattering agents include fine particle metal oxides (titanium oxide, titanium dioxide, zinc oxide, zirconium oxide, cerium oxide, etc.) which may be surface-treated.

[0043] Examples of sequestering agents include 1-hydroxyethane-1,1-diphosphonic acid, 1-hydroxyethane-1,1-diphosphonic acid tetrasodium salt, edetate disodium, edetate trisodium, edetate tetrasodium, sodium citrate, sodium polyphosphate, sodium metaphosphate, gluconic acid, phosphoric acid, citric acid, ascorbic acid, succinic acid, edetic acid, and ethylenediaminehydroxyethyltriacetate trisodium salt.

[0044] Examples of pearlescent agents include glycol distearate and titanium mica.

[0045] Examples of amino acids include neutral amino acids (e.g., threonine, cysteine, etc.); basic amino acids (e.g., hydroxylysine, etc.); and the like. For example, sodium acyl sarcosine (sodium lauroyl sarcosine), Examples of the anti-inflammatory agent include glutamic acid salts, acyl β-alanine sodium, glutathione, and pyrrolidone carboxylic acid.

[0046] Examples of organic amines include monoethanolamine, diethanolamine, triethanolamine, morpholine, triisopropanolamine, 2-amino-2-methyl-1,3-propanediol, and 2-amino-2-methyl-1-propanol.

[0047] Examples of organic and inorganic salts include hydrochloric acid, citric acid, gluconic acid, succinic acid, acetic acid, tartaric acid, sorbic acid, lactic acid, maleic acid, sulfuric acid, phosphoric acid, malic acid, arginine, aqueous ammonia, diisopropanolamine, diethanolamine, triisopropanolamine, triethanolamine, monoethanolamine, potassium hydroxide, calcium hydroxide, and sodium hydroxide, or salts thereof.

[0048] Examples of polymer emulsions include acrylic resin emulsion, polyethyl acrylate emulsion, acrylic resin liquid, polyacrylic alkyl ester emulsion, polyvinyl acetate resin emulsion, and natural rubber latex.

[0049] Examples of pH adjusters include buffers such as lactic acid-sodium lactate, citric acid-sodium citrate, and succinic acid-sodium succinate, and are usually used to adjust the pH of the internal phase (aqueous component).

[0050] Examples of vitamins include vitamins A, B1, B2, B6, C, E and their derivatives, pantothenic acid and its derivatives, biotin, etc.

[0051] Examples of antioxidants include tocopherols, dibutylhydroxytoluene (BHT), butylhydroxyanisole, pyrosulfite, gallic acid ester, phosphoric acid, citric acid, ascorbic acid, maleic acid, malonic acid, succinic acid, fumaric acid, cephalin, hexametaphosphate, phytic acid, and ethylenediaminetetraacetate.

[0052] Examples of preservatives include parabens and phenoxyethanol.

[0053] Examples of water-soluble polymers include plant-based polymers (e.g., gum arabic, tragacanth gum, galactan, guar gum, carob gum, karaya gum, carrageenan, pectin, agar, quince seed (marmelo), algae colloid (cassow extract), starch (coconut oil), and the like. (corn, potato, wheat), glycyrrhizic acid); microbial polymers (e.g. natural water-soluble polymers such as xanthan gum, dextran, succinoglucan, pullulan, etc.; animal polymers (e.g., collagen, casein, albumin, gelatin, etc.); semi-synthetic water-soluble polymers such as starch-based polymers (e.g., carboxymethyl starch, methylhydroxypropyl starch, etc.); cellulose-based polymers (hydroxypropylmethylcellulose, hydroxyethylcellulose, hydroxypropylcellulose, methylcellulose, ethylcellulose, hydroxypropylmethylcellulose stearoxy ether, sodium cellulose sulfate, carboxymethylcellulose, sodium carboxymethylcellulose, crystalline cellulose, cellulose powder, etc.); alginic acid-based polymers (e.g., sodium alginate, propylene glycol alginate, etc.), etc. Examples include synthetic water-soluble polymers such as polyoxyethylene polymers (for example, polyethylene glycol 20,000, 40,000, 60,000, etc.); polyethyleneimine; and cationic polymers.

[0054] The various active ingredients include, for example, anti-inflammatory agents (e.g., salicylic acid derivatives, hinokitiol, , zinc oxide, allantoin, etc.); whitening agents (e.g., placenta extract, saxifrage extract, arbutin, resorcinol derivatives, etc.); various extracts (e.g., Phellodendron bark, Coptis chinensis, Lithospermum root, Peony, Swertia japonica, Birch, sage, Loquat, Carrot, Aloe, Mallow, Iris, Grape, Job's tears, Loofah, Lily, Saffron, Cnidium rhizome, Angelica acutiloba, Garlic, Chili pepper, Citrus fruit, Angelica acutiloba, Seaweed, etc.), activators (e.g., Royal jelly, photosensitizers, cholesterol derivatives, etc.); blood circulation promoters (e.g., Examples include nonylic acid valenylamide, nicotinic acid benzyl ester, nicotinic acid β-butoxyethyl ester, capsaicin, zingerone, cantharides tincture, ichthammol, tannic acid, α-borneol, tocopherol nicotinate, inositol hexanicotinate, cyclandelate, cinnarizine, tolazoline, acetylcholine, verapamil, cepharanthine, γ-oryzanol, etc.; antiseborrheic agents (e.g., sulfur, thianthol, etc.); anti-inflammatory agents (e.g., tranexamic acid, thiotaurine, hypotaurine, etc.); and the like.

[0055] These optional components can be added in any step of the present invention or before or after the step.

[0056] <Manufacturing method> One aspect of the present invention is The present invention relates to a method for producing an oil-in-water cosmetic (hereinafter sometimes referred to as the "production method of the present invention"), which comprises the step of blending the following components (A) and (B): (A) 0.2 to 1.0% by mass of dipotassium glycyrrhizinate relative to the total amount of the cosmetic, (B) Polyethylene glycol fatty acid ester. The matters explained in the above section <Cosmetics> are all applicable to the explanation of the production method of the present invention.

[0057] The manufacturing method of the present invention is characterized by producing a cosmetic preparation with reduced stickiness by blending specific components (A) and (B). The specific ranges of the blending amounts and blending ratios of components (A) and (B) are the same as those explained in the section on <Cosmetics> above.

[0058] The cosmetic preparation of the present invention can be produced by a conventional method, except that it contains the above-mentioned essential components. For example, the oil phase components are heated and dissolved, and the oil phase is added to the water phase components containing the heated and dissolved components (A) and (B), followed by emulsification with stirring to obtain an oil-in-water emulsion-type topical skin preparation. [Example]

[0059] The present invention will be specifically described below with reference to examples, but these are merely examples of the present invention and the scope of the present invention is not limited to these examples.

[0060] The oil phase components were heated to 70°C and dissolved according to the formulation shown in Table 1. The oil phase was added to the aqueous phase components that had also been heated and dissolved at 70°C, and the mixture was emulsified while stirring with a homomixer to prepare an oil-in-water emulsion cosmetic. The polyethylene glycol fatty acid esters used were PEG-25 stearate (NIKKOL MYS-25V (manufactured by Nikko Chemicals Co., Ltd.)), PEG-100 stearate (EMALEX 8100R (manufactured by Nippon Emulsion Co., Ltd.)), and PEG-150 stearate (EMANON 3199VB (manufactured by Kao Corporation)). Each of the obtained cosmetics was evaluated for the following items, and the results are shown in Table 1.

[0061] (non-sticky) An appropriate amount of the cosmetic was applied to the skin, and the stickiness of the skin one minute after application was scored by a specialist evaluator according to the following criteria. 5 points: No stickiness 4 points: Almost no stickiness 3 points: Feels slightly sticky 2 points: Sticky feeling 1 point: Very sticky The average scores of the 10 evaluators were assigned to the following evaluations. ◎: Over 4 points: Very good ○: Over 3 points and 4 points or less: Good △: More than 2 points and 3 points or less: Slightly poor × : 2 points or less : Defective

[0062] (No creaking sensation) An appropriate amount of the cosmetic was applied to the skin, and the feeling of roughness felt on the skin during application was scored by a specialist evaluator according to the following criteria. 5 points: No creaking sensation 4 points: Almost no creaking sensation 3 points: Slight creaking sensation 2 points: Feels creaky 1 point: Very creaky The average scores of the 10 evaluators were assigned to the following evaluations. ◎: Over 4 points: Very good ○: Over 3 points and 4 points or less: Good △: More than 2 points and 3 points or less: Slightly poor × : 2 points or less : Defective

[0063] (Moisturizing) An appropriate amount of the cosmetic was applied to the skin, and the moist feeling of the skin one minute after application was scored by a specialist evaluator according to the following criteria. 5 points: Feels very moist 4 points: Feels moist 3 points: Feels slightly moist 2 points: Almost no moist feeling 1 point: No moist feeling The average scores of the 10 evaluators were assigned to the following evaluations. ◎: Over 4 points: Very good ○: Over 3 points and 4 points or less: Good △: More than 2 points and 3 points or less: Slightly poor × : 2 points or less : Defective

[0064] (Stability of formulation) Each cosmetic was placed in a glass standard bottle and left to stand in a thermostatic chamber set at 0°C for one month, after which a specialist evaluator visually evaluated the cosmetic properties using the following four-point scale. ◎: No crystalline precipitation is observed ○: Very little crystalline precipitation is observed △: A small amount of crystalline precipitate is observed ×: Crystalline deposits observed

[0065] [Table 1]

[0066] The cosmetics of the examples containing components (A) and (B) were found to be excellent in terms of non-stickiness. Furthermore, they also had excellent usability, such as a non-squeaky feeling and a moist feeling (non-drying feeling), and excellent formulation stability, such as suppression of crystal precipitation. On the other hand, Comparative Example 1, which did not contain component (B), and Comparative Example 2, in which component (A) exceeded the specified range, had an unsatisfactory feel when used.Furthermore, the stability of the formulation was also insufficient. [Industrial Applicability]

[0067] The present invention can be applied to cosmetics including quasi-drugs.

Claims

1. The following components (A) and (B): (A) 0.2 to 1.0% by mass of dipotassium glycyrrhizinate relative to the total mass of the cosmetic; (B) polyethylene glycol fatty acid ester, An oil-in-water cosmetic comprising:

2. 2. The oil-in-water cosmetic according to claim 1, wherein the polyethylene glycol fatty acid ester of component (B) comprises polyethylene glycol stearate and / or polyethylene glycol distearate.

3. The oil-in-water cosmetic according to claim 1, wherein the polyethylene glycol fatty acid ester of component (B) comprises one or more selected from PEG-25 stearate, PEG-100 stearate, and PEG-150 stearate.

4. The oil-in-water cosmetic according to claim 1, comprising 0.05 to 15% by mass of component (B) relative to the total mass of the cosmetic.

5. 2. The oil-in-water cosmetic according to claim 1, wherein the mass ratio of the contents of components (A) and (B) ((B) / (A)) is 0.05 to 60.

6. The following components (A) and (B): (A) 0.2 to 1.0% by mass of dipotassium glycyrrhizinate relative to the total mass of the cosmetic; (B) polyethylene glycol fatty acid ester, A method for producing an oil-in-water cosmetic, comprising the step of blending

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