Pressure vessel and pressure wave measurement method

Abstract

To provide a technology relating to a pressure vessel that can measure pressure waves emitted from a pressure device with high accuracy.SOLUTION: The pressure vessel comprises a pressure chamber capable of accommodating a sample, a pressurizing device that emits a pressure wave into the pressure chamber when activated, a pressure sensor that measures the pressure wave emitted from the pressurizing device, and a pressure wave transmission medium liquid that fills the pressure chamber so that no gaps are formed between the pressure chamber and the inner wall surface that defines the chamber.SELECTED DRAWING: Figure 2

Description

[Technical Field]

[0001] The present invention relates to a pressure vessel and a method for measuring pressure waves. [Background technology]

[0002] There is known a pressure vessel equipped with a pressure device that generates pressure waves (including shock waves) and that can pressurize a sample contained in a pressure chamber by the pressure waves generated by the pressure device (see, for example, Patent Document 1). In such a pressure vessel, the sample contained in the pressure chamber can be subjected to a pressure treatment according to the purpose by exposing the sample to the pressure waves emitted by the pressure device. [Prior art documents] [Patent documents]

[0003] [Patent Document 1] International Publication No. 2021 / 085491 Summary of the Invention [Problem to be solved by the invention]

[0004] In pressure treatment of a sample using a pressure vessel, it is important to accurately measure the magnitude of the pressure applied to the sample when the pressure device is operated in order to accurately understand the effect on the sample.

[0005] The technology of the present disclosure has been made in consideration of the above-mentioned circumstances, and aims to provide technology relating to a pressure vessel that can measure pressure waves emitted from a pressurizing device with high accuracy. [Means for solving the problem]

[0006] As a result of extensive research, the present inventors have found that by operating a pressurizing device while the pressure chamber is filled with a pressure wave transmission medium liquid so that no gaps are formed in the pressure chamber, and measuring the pressure waves emitted into the pressure chamber by the pressurizing device, the pressure waves can be measured with high accuracy. The present disclosure has been completed based on this finding.

[0007] The technology disclosed herein is a pressure chamber capable of accommodating a sample; a pressure device that, when activated, emits a pressure wave into the pressure chamber; a pressure sensor for measuring pressure waves emitted from the pressure device; a pressure wave transmission medium liquid filling the pressure chamber so that no gap is formed between the pressure chamber and an inner wall surface that defines the pressure chamber; A pressure vessel comprising:

[0008] The pressurizing device may be a pyrotechnic pressurizing device that has a metal explosive container that contains explosives and that controls ignition of the explosives by receiving a supply of operating power.

[0009] Furthermore, the technology according to the present disclosure can be specified as a method for measuring pressure waves. The method for measuring pressure waves according to the present disclosure includes: A step of placing a sample and a pressure wave transmission medium liquid in a pressure chamber of a pressure vessel; activating a pressurizing device of the pressure vessel to emit a pressure wave from the pressurizing device into the pressure chamber; measuring the pressure waves emitted by the pressurizing device into the pressure chamber with a pressure sensor in the pressure vessel; Equipped with The pressure sensor measures the pressure wave in a state where the pressure chamber is filled with the pressure wave transmission medium liquid so that no gap is formed between the pressure chamber and the inner wall surface that defines the pressure chamber. [Effects of the Invention]

[0010] According to the present disclosure, it is possible to provide a technology relating to a pressure vessel that can measure pressure waves emitted from a pressurizing device with high accuracy. [Brief explanation of the drawings]

[0011] [Figure 1] FIG. 1 is a diagram illustrating the schematic configuration of a pressure vessel. [Figure 2] FIG. 2 is a diagram illustrating the schematic configuration of the pressure vessel. [Figure 3] FIG. 3 is a graph showing the measurement results of pressure profiles during pressure treatment in the embodiment and the comparative example. DETAILED DESCRIPTION OF THE INVENTION

[0012] A pressure vessel according to an embodiment of the present disclosure will be described below with reference to the drawings. Note that each configuration and combination thereof in the embodiment is merely an example, and addition, omission, substitution, and other modifications of the configuration are possible as appropriate within the scope of the gist of the present disclosure. The present disclosure is not limited by the embodiment, but is limited only by the claims.

[0013] <Embodiment> FIG. 1 is a diagram illustrating the schematic configuration of a pressure vessel 1 according to an embodiment. The pressure vessel 1 is a metal vessel comprising a vessel body 2 and a lid 3 that is detachable from the vessel body 2. A hollow pressure chamber 8 capable of containing a sample is formed inside the pressure vessel 1. The pressure vessel 1 comprises an initiator 4 as a pressurizing device that emits a pressure wave into the pressure chamber 8 when activated, a pressure sensor that measures the pressure wave emitted from the pressurizing device, and a pressure wave transmission medium liquid that fills the pressure chamber so that no gaps are formed between the initiator 4 and the inner wall surface that defines the pressure chamber.

[0014] The initiator 4 is, for example, a pyrotechnic pressurizing device, and is activated when a pressurizing process is performed in which high pressure is applied to a sample contained in the pressure chamber 8. The initiator 4 receives a supply of operating power to control the ignition of explosives, thereby releasing a generated pressure wave (shock wave) into the pressure chamber 8. As a result, the pressure wave (shock wave) can be applied to the sample contained in the pressure chamber.

[0015] There are no particular limitations on the sample contained in the pressure chamber 8 of the pressure vessel 1, i.e., the sample to be subjected to pressure treatment by the pressure vessel. In addition to the sample, the pressure chamber 8 of the pressure vessel 1 is filled with a pressure wave transmission medium liquid, which is a liquid medium for facilitating the transmission of pressure waves to the sample.

[0016] The container body 2 is, for example, a metal container having a roughly cylindrical outer shape, and has, for example, a cylindrical side wall portion 21 and a bottom wall portion 22 provided in the middle portion of the side wall portion 21 in the vertical direction. However, the shape of the container body 2 is not particularly limited. An upper end opening 23 is formed on the upper end side of the container body 2 as an open end. A lid portion 3 can be detachably attached to the upper end opening 23 of the container body 2.

[0017] 2 is a diagram showing the state in which the lid 3 is attached to the upper opening 23 of the container body 2. With the lid 3 attached to the upper opening 23 of the container body 2, the pressure chamber 8 of the pressure vessel 1 is sealed airtight and liquidtight. Here, the inner surfaces of the side wall 21 and the bottom wall 22 of the container body 2 that face the pressure chamber 8 are referred to as "side inner surface 24" and "bottom inner surface 25", respectively. 2 indicates the axis of the pressure chamber 8. In the following description, for convenience, the direction of the axis X1 of the pressure chamber 8 may be referred to as the depth direction (vertical direction) of the pressure chamber 8, and the direction perpendicular to the axis X1 may be referred to as the cross-sectional direction of the pressure chamber 8.

[0018] The pressure vessel 1 includes an initiator 4 as a (pyrotechnic) pressurizing device. The initiator 4 is, for example, an electric igniter including a cup-shaped explosive container 41 for containing explosive, a pair of conductive pins 42, and the like. In one embodiment, the initiator 4 is provided in the lid 3 of the pressure vessel 1. When the lid 3 is attached to the vessel body 2, the explosive container 41 in the initiator 4 is disposed facing the pressure chamber 8 so as to face the pressure chamber 8, as shown in FIG. 2 . The explosive container 41 includes, for example, a side surface 41A that forms a side portion of the explosive container 41 and a cleavage surface 41B that forms the bottom of the explosive container 41. The side surface 41A of the explosive container 41 has, for example, a cylindrical shape and extends along the axis X1 direction (depth direction) of the pressure chamber 8. The cleavage surface 41B is connected to the bottom end of the side surface 41A and extends along the cross-sectional direction (direction perpendicular to the axis X1) of the pressure chamber 8. The bottom end of the side surface 41A is the end located on the bottom side of the pressure chamber 8.

[0019] An ignition current for igniting the explosive contained in the explosive container 41 is supplied to a pair of conductive pins 42 in the initiator 4. The base ends of the pair of conductive pins 42 are inserted into the explosive container 41 while being maintained in an electrically insulated state, and a bridge wire (resistor) (not shown) is connected between the base ends of the pair of conductive pins 42. The bridge wire may be, for example, a nichrome wire. The explosive may be ZPP (zirconium-potassium perchlorate), ZWPP (zirconium-tungsten-perchlorate), or the like. Alternatively, the explosive may be titanium hydride-potassium perchlorate (THPP), lead tricinate, or the like. The explosive is contained in the explosive container 41 in contact with the bridge wire. The explosive container 41 is formed of a thin-walled metal member such as aluminum.

[0020] When the initiator 4 is activated, the bridge wire is heated by an operating current (ignition current) supplied to the pair of conductive pins 42. As a result, the explosive in the explosive container 41 is ignited and burns. Then, as the explosive contained in the explosive container 41 burns, the pressure inside the explosive container 41 increases, and the cleavage surface 41B of the explosive container 41 cleaves. The cleavage surface 41B is disposed opposite the pressure chamber 8 when the lid 3 is attached to the container body 2. The cleavage surface 41B of the explosive container 41 is configured to be cleaved more easily by the combustion energy of the explosive than the side surface 41A. In other words, the cleavage surface 41B of the explosive container 41 can be said to be a surface configured to be cleaved by the combustion energy of the explosive when the initiator 4 is activated. For example, an easy-to-crack portion is formed on the cleavage surface 41B of the explosive container 41, the metal member having a thinner wall thickness than other portions, so that the cleavage surface 41B is easily cleaved by the combustion energy of the explosive when the initiator 4 is activated. The easy-to-crack portion may be formed, for example, by performing a thinning process such as half-cutting on the metal member that forms the cleavage surface 41B.

[0021] When the cleavage surface 41B of the explosive container 41 is cleaved by the combustion energy of the explosive, combustion products (combustion gas of the explosive) are released from the cleavage site into the pressure chamber 8 as a pressure wave (shock wave). In this way, the initiator 4 controls the ignition of the explosive contained in the explosive container 41 by receiving the supply of operating power, and the pressure wave (shock wave) generated by the ignition control The shock wave is released into the pressure chamber 8.

[0022] Reference numeral 5 in FIG. 2 denotes a sample to be subjected to pressure treatment using the pressure vessel 1. The sample 5 is placed in the pressure chamber 8 of the pressure vessel. The sample 5 is not particularly limited. The sample 5 may be a solid, a liquid, or a mixture thereof. In this embodiment, a cell-containing solution is used as the sample 5, as an example. As shown in FIG. 2, the sample 5 is placed in the pressure chamber 8 while being accommodated in a sample container 50. The type of the sample container 50 is not particularly limited, but it is preferably made of a material that can smoothly transmit the pressure wave (shock wave) released into the pressure chamber 8 upon activation of the initiator 4 to the sample 5 and that will not burst when exposed to the pressure wave (shock wave). The sample container 50 may be, for example, a pouch with appropriate flexibility. The pressure chamber 8 may be formed with a mounting portion for mounting the sample container 50 in a fixed position. The mounting portion may be configured to allow the sample container 50 to be placed in a predetermined orientation, for example. For example, an installation portion may be formed near the center of the bottom inner surface 25 of the bottom wall portion 22 of the container body 2, and the sample container 50 may be installed in this installation portion.

[0023] Reference numeral 7 denotes a pressure wave transmission medium liquid filled in the pressure chamber 8 of the pressure vessel 1. The pressure wave transmission medium liquid 7 is a liquid medium for transmitting the pressure waves (shock waves) emitted from the initiator 4 to the pressure chamber 8 to the sample 5. When the initiator 4 is activated, the transmission of the pressure waves (shock waves) to the sample 5 is promoted via the pressure wave transmission medium liquid 7. The type of pressure wave transmission medium liquid 7 is not particularly limited, and examples include water, an aqueous solution, an organic solvent, an ionic liquid, and a gel-like liquid. These liquid solvents may be used alone or in combination of two or more. Of these, water or a liquid having a bulk modulus similar to that of water is preferred, and water is particularly preferred.

[0024] Reference numeral 6 denotes a pressure release valve. The pressure release valve 6 is configured to receive operating power from, for example, a power source (not shown) and is controlled by receiving the operating power. The pressure release valve 6 is closed when the initiator 4 of the pressure vessel 1 is activated, and its operation may be controlled by programming so that it opens when a predetermined time has elapsed after the initiator 4 starts operating. Furthermore, for example, the pressure release valve 6 may be automatically opened when the pressure in the pressure chamber 8 rises to a predetermined pressure during operation of the initiator 4. There are no particular limitations on the location where the pressure release valve 6 is installed, but in the embodiment shown in FIG. 2 , the pressure release valve 6 is provided on the side wall portion 21 of the vessel body 2.

[0025] Reference numeral 9 denotes a pressure sensor. The pressure sensor 9 is a sensor for measuring the pressure wave (shock wave) emitted from the initiator 4 to the pressure chamber 8 when the initiator 4 is activated, in other words, the pressure profile of the pressure wave to which the sample 5 will be exposed. The pressure sensor 9 is, for example, a piezoelectric sensor having a piezoelectric element. The piezoelectric element of the pressure sensor 9 is disposed, for example, facing the inside of the pressure chamber 8 or in communication with the pressure chamber 8, and is disposed so as to be exposed to the pressure wave (shock wave) emitted from the initiator 4. There are no particular limitations on the location where the pressure sensor 9 is installed, but in the embodiment shown in FIG. 2, the pressure sensor 9 is installed on the bottom wall portion 22 of the container body 2.

[0026] In the pressure vessel 1 configured as described above, the pressure chamber 8 is placed in a high-pressure state due to the pressure waves (shock waves) emitted by the initiator 4. The pressure vessel 1 is designed so that the lid 3 can be fastened integrally to the vessel body 2 so that the pressure chamber 8 can be kept airtight even when the initiator 4 is operating. For example, a gasket may be interposed between the lid 3 and the vessel body 2 to improve the airtightness of the pressure chamber 8. Furthermore, the lid 3 and the vessel body 2 may be fastened together with high-strength bolts.

[0027] Next, we will explain the procedure and operation of using the pressure vessel 1. In preparation for pressurizing the sample 5, first, as shown in Figure 1, the lid 3 is removed from the vessel body 2 of the pressure vessel 1, and the sample 5 is placed in the pressure chamber 8. For example, a sample container 50 containing the sample 5 is placed on the installation part of the pressure chamber 8. Then, the pressure chamber 8 is filled with a pressure wave transmission medium liquid 7 (for example, water).

[0028] Thereafter, the lid 3 is attached and fastened to the vessel body 2, making the pressure chamber 8 airtight. The initiator 4, pressure release valve 6, etc. are connected to a power source via wiring. The supply of operating power from the power source to the initiator 4 and pressure release valve 6 is controlled by a control device. The control device is not particularly limited, but may be, for example, a general-purpose computer equipped with an input section, a processing section, an output section, etc. When the sample 5 is pressurized using the pressure vessel 1, a pressure sensor 9 measures the pressure profile (pressure waveform) of the pressure wave to which the sample 5 is exposed during the pressurization process. The pressure sensor 9 is connected to the input section of the control device via wiring, etc., and the control device can acquire the output signal of the pressure sensor 9.

[0029] When the initiator 4 receives the supply of operating current, it controls the ignition of the explosive contained in the explosive container 41. Then, as described above, the combustion energy of the explosive causes the cleavage surface 41B of the explosive container 41 to cleave, and a pressure wave is released into the pressure chamber 8. The pressure wave released into the pressure chamber 8 propagates through the pressure wave transmission medium liquid 7, and the sample 5 contained in the sample container 50 is pressurized. Here, since the sample container 50 has an appropriate degree of flexibility (flexibility), the sample container 50 can be pressurized without bursting.

[0030] The sample 5 is, for example, a solution containing cells. As an example, the pressure vessel 1 can be used to partially damage the surface of the cells contained in the sample 5 without crushing them. In this way, by applying pressure to the cells, a desired cell processed product can be obtained. The pressure treatment may be performed, for example, so that the pressure profile of the pressure wave applied to the sample 5 includes the following conditions (1) to (3). (1) The maximum pressure is 37 MPa or more and 500 MPa or less; (2) The time from the start of pressure rise to the time when the maximum value is reached is 0.5 ms or less, and (3) The time from when the pressure starts to decay from the maximum value to when the pressure decays to half of the maximum value is 5 ms or less.

[0031] A pressure wave having the pressure profile specified as above can be generated by adjusting the type, amount, characteristics, etc. of the explosive contained in the explosive container 41 of the initiator 4, or by adjusting the valve opening timing, opening degree, etc. of the pressure release valve 6 that is actuated following the actuation of the initiator 4. The above pressurization treatment may be performed on the sample 5 only once, or may be repeated multiple times.

[0032] The cells contained in sample 5 are not particularly limited. The type of cells is also not particularly limited, and may be either prokaryotic cells (e.g., cells of Escherichia coli, lactic acid bacteria, Bacillus subtilis var. natto, etc.) or eukaryotic cells. The eukaryotic cells are also not particularly limited, and may be either plant cells (e.g., angiosperm cells, gymnosperm cells, algae cells, etc.), animal cells (e.g., human cells, non-human mammalian cells, avian cells, reptile cells, amphibian cells, fish cells, insect cells, etc.), or microbial cells (e.g., yeast, filamentous fungi, etc.).

[0033] There is no particular limitation on the concentration of cells contained in the sample 5. Furthermore, the sample 5 can be contained in the sample container 50 in a form in which the cells are contained in a liquid. In other words, the sample 5 may be a cell suspension containing cells. The liquid contained in the sample 5 is not particularly limited, but it is preferably a substance with an acoustic impedance close to that of the pressure wave transmission medium liquid 7 so as not to inhibit the pressure waves, and examples thereof include silicone resin, fluororesin (e.g., PFA (perfluoroalkoxy) Examples of the liquid that can be used include polymers such as alkane polymers (FEP (perfluoroethylene propene copolymer)), and FEP (perfluoroethylene propene copolymer). Typically, water can be used as the liquid containing the cells. The liquid can contain any component other than the cells. These optional components can be used alone or in combination of two or more.

[0034] Pressurization using the pressure vessel 1 causes partial damage to the surface of cells contained in the sample 5. Such processed cell products may have exogenous molecules introduced into the cells via the surface damage. Furthermore, the processed cell products may be, for example, cells lacking at least some of their cytoplasmic components, or cytoplasmic components released from cells. These processed cell products can be reused for other purposes.

[0035] Of course, the pressure vessel 1 may also be pressurized for the purpose of disrupting cells contained in the sample 5. Cell disruption can also be used, for example, to obtain intracellular materials such as DNA, RNA, proteins, and organelles from cells and perform molecular diagnostics (e.g., pathogen detection platforms, immunoassays for point-of-care diagnostics, protein purification for studying protein function, structure, etc., cancer diagnosis, drug screening, mRNA transcriptome determination, and compositional analysis of specific proteins, lipids, and nucleic acids).

[0036] When a pressure treatment is performed on a sample 5 using a pressure vessel 1, it is important to accurately measure the pressure profile (pressure waveform) of the pressure wave to which the sample 5 is actually exposed during the pressure treatment. After extensive investigation, the present inventors have found that if the initiator 4 is operated when the pressure chamber 8 is insufficiently filled with the pressure wave transmission medium liquid 7, i.e., when gaps are formed in the pressure chamber 8, variations occur in the pressure profile (pressure waveform) of the pressure wave measured by the pressure sensor 9. Therefore, in this embodiment, the initiator 4 is operated with the pressure chamber 8 filled with the pressure wave transmission medium liquid 7 so that no gaps are formed between the initiator 4 and the inner wall surfaces (the side inner surface 24, bottom inner surface 25 of the container body 2, and the lid inner surface 26 of the lid 3) that define the pressure chamber 8, and the pressure profile (pressure waveform) of the pressure wave emitted by the initiator 4 into the pressure chamber 8 is measured by the pressure sensor 9.

[0037] As described above, the pressure vessel 1 in this embodiment has: a pressure chamber 8 capable of accommodating a sample 5; an initiator 4 (pressurizing device) that, when activated, emits a pressure wave into a pressure chamber 8; a pressure sensor 9 for measuring the pressure wave emitted from the initiator 4 into the pressure chamber 8; and a pressure wave transmission medium liquid 7 that fills the pressure chamber 8 so that no gaps are formed between the inner wall surfaces (the side inner surface 24, the bottom inner surface 25 of the container body 2, and the lid inner surface 26 of the lid 3) that define the pressure chamber 8 and the pressure wave transmission medium liquid 7.

[0038] Furthermore, the method for measuring pressure waves using the pressure vessel 1 in this embodiment is as follows: a step of placing a sample 5 and a pressure wave transmission medium liquid 7 in a pressure chamber 8 of a pressure vessel 1; activating an initiator 4 (pressurizing device) of the pressure vessel 1 to emit a pressure wave from the initiator 4 to the pressure chamber 8; measuring the pressure wave emitted by the initiator 4 into the pressure chamber 8 by the pressure sensor 9 of the pressure vessel 1; Equipped with The pressure sensor 9 measures the pressure wave while the pressure chamber 8 is filled with the pressure wave transmission medium liquid 7 so that no gaps are formed between the inner wall surfaces (the side inner surface 24, bottom inner surface 25 of the container body 2, and the lid inner surface 26 of the lid 3) that define the pressure chamber 8 and (the pressure wave transmission medium liquid 7).

[0039] FIG. 3 is a graph showing the measurement results of pressure profiles during pressurization in an embodiment and comparative examples. The "embodiment" shown in FIG. 3 shows the measurement results of the pressure profile when the pressure chamber 8 was filled with the pressure wave transmission medium liquid 7 so that no gaps were formed (no gaps) and the initiator 4 was operated. Comparative Example 1 shows the measurement results of the pressure profile when the initiator 4 was operated in a state where a 1 cc gap was formed in the pressure chamber 8 (the gap volume between the liquid level of the pressure wave transmission medium liquid 7 and the inner surface 26 of the lid) was 1 cc. Comparative Example 2 shows the measurement results of the pressure profile when the initiator 4 was operated in a state where a 2 cc gap was formed in the pressure chamber 8 (the gap volume between the liquid level of the pressure wave transmission medium liquid 7 and the inner surface 26 of the lid) was 2 cc. In FIG. 3, the embodiment is shown with a solid line, Comparative Example 1 with a dashed line, and Comparative Example 2 with a dashed line.

[0040] According to an embodiment in which the pressure chamber 8 is filled with the pressure wave transmission medium liquid 7 so that no gaps are formed in the pressure chamber 8, the pressure of the pressure wave emitted into the pressure chamber 8 can be accurately measured by the piezoelectric element of the pressure sensor 9 without being affected by an air layer. Comparing the measurement results shown in FIG. 3 , in Comparative Examples 1 and 2 in which gaps are formed in the pressure chamber 8, it was confirmed that the pressure values ​​of the pressure profile measured by the pressure sensor 9 tended to be smaller due to the influence of the air layer formed in the gap in the pressure chamber 8. It was also confirmed that Comparative Example 2, in which the gap volume of the pressure chamber 8 was relatively large, had a larger measurement error in the pressure profile than Comparative Example 1. As described above, the pressure vessel 1 of this embodiment and the method for measuring a pressure waveform during pressurization using this vessel make it possible to measure with high accuracy the pressure profile of the pressure wave emitted from the initiator 4 to the pressure chamber 8 during pressurization.

[0041] It should be noted that there are no particular limitations on the locations where the initiator 4, pressure release valve 6, pressure sensor 9, etc. are installed in the above-described pressure vessel 1. Furthermore, in the above-described embodiment, the initiator 4 is used as an example of a pyrotechnic pressurizing device, but a pressurizing device other than a pyrotechnic pressurizing device may also be used as long as it is capable of releasing a pressure wave into the pressure chamber 8 when activated.

[0042] Although the embodiments according to the present disclosure have been described above, each aspect disclosed in this specification can be combined with any other feature disclosed in this specification. [Explanation of symbols]

[0043] 1. Pressure vessel 2. Container body 3...Lid part 4. Initiator 5. Sample 6. Pressure relief valve 7. Pressure wave transmission medium liquid 8. Pressure chamber 9. Pressure sensor

Claims

1. a pressure chamber capable of accommodating a sample; a pressure device that, when activated, emits a pressure wave into the pressure chamber; a pressure sensor for measuring pressure waves emitted from the pressure device; a pressure wave transmission medium liquid filling the pressure chamber so that no gap is formed between the pressure chamber and an inner wall surface that defines the pressure chamber; Equipped with Pressure vessel.

2. the pressurizing device is a pyrotechnic pressurizing device that has a metal explosive container that contains explosives and controls ignition of the explosives by receiving a supply of operating power; The pressure vessel of claim 1.

3. A step of placing a sample and a pressure wave transmission medium liquid in a pressure chamber of a pressure vessel; activating a pressurizing device of the pressure vessel to emit a pressure wave from the pressurizing device into the pressure chamber; measuring the pressure waves emitted by the pressurizing device into the pressure chamber with a pressure sensor in the pressure vessel; Equipped with the pressure sensor measures the pressure wave in a state where the pressure chamber is filled with the pressure wave transmission medium liquid so that no gap is formed between the pressure chamber and an inner wall surface that defines the pressure chamber. How to measure pressure waves.

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