Catheter set and measurement system

Abstract

To provide a catheter set capable of performing safe measurement.SOLUTION: A catheter set includes a catheter 15 and a measurement probe. The catheter 15 includes: an opening part 151 arranged on a tip side; a flow channel 156 arranged between the opening part and a rear end side; and a probe duct 157 arranged in parallel with the flow channel 156. The measurement probe includes a light guide body to be insertable to the probe duct 157. The catheter 15 includes a projection prevention part 159 for preventing the light guide body from projecting from a tip side of the probe duct 157.SELECTED DRAWING: Figure 24

Description

[Technical Field]

[0001] The present invention relates to a catheter set and a measurement system. [Background technology]

[0002] Various catheters are used in medical settings, such as indwelling bladder catheters and intravascular catheters. A device has been proposed that measures oxygen in the bladder by inserting a sensor into the bladder via an indwelling bladder catheter (Patent Document 1). [Prior art documents] [Patent documents]

[0003] [Patent Document 1] Special Publication No. 9-505505 Summary of the Invention [Problem to be solved by the invention]

[0004] However, in the device of Patent Document 1, the sensor protrudes from the tip of the catheter. Therefore, the sensor may come into direct contact with the bladder lining or the like due to the patient's body movements, etc., and cause injury. In addition, since the device measures the bladder wall, it cannot be said that it is actually measuring the oxygen in the urine. In one aspect, it is an object to provide a catheter set or the like that allows for safe measurement. [Means for solving the problem]

[0005] A catheter set comprising a catheter and a measurement probe, wherein the catheter has an opening at the tip end, a flow path provided between the opening and the rear end, and a probe conduit arranged parallel to the flow path, the measurement probe has a light guide that can be inserted into the probe conduit, and the catheter further has a protrusion prevention portion that prevents the light guide from protruding from the tip end of the probe conduit. [Effects of the Invention]

[0006] In one aspect, it is possible to provide a catheter set or the like that allows safe measurement. [Brief explanation of the drawings]

[0007] [Figure 1] FIG. 1 is an explanatory diagram illustrating a configuration of a measurement system. [Figure 2] FIG. 1 is an enlarged cross-sectional view of the tip of an indwelling bladder catheter into which a measurement probe is inserted. [Figure 3A] FIG. 3 is a cross-sectional view taken along line IIIA-IIIA in FIG. 2. [Figure 3B] FIG. 3 is a cross-sectional view taken along line IIIB-IIIB in FIG. 2. [Figure 4A] FIG. 2 is an explanatory diagram illustrating the configuration of a measurement probe. [Figure 4B] FIG. 2 is a cross-sectional view of a connection hub. [Figure 5A] FIG. 2 is a perspective view of a hub rigid member. [Figure 5B] FIG. [Figure 6] FIG. [Figure 7] FIG. 2 is an explanatory diagram illustrating the configuration of a measurement device. [Figure 8] 10 is a flowchart illustrating the flow of processing of a program. [Figure 9A] FIG. 10 is a perspective view of the tip of a measurement probe according to Modification 1-1. [Figure 9B] FIG. 10 is an explanatory diagram illustrating the configuration of a measurement probe according to Modification 1-2. [Figure 9C] FIG. 10 is a perspective view of the tip of a measuring probe according to Modification 1-3. [Figure 10A] FIG. 10 is a perspective view of the tip of a measurement probe according to Modification 1-4. [Figure 10B] 10B is a cross-sectional view taken along line XB-XB in FIG. 10A. [Figure 11A] FIG. 10 is a perspective view of the tip of a measurement probe according to Modification 1-5. [Figure 11B] FIG. 10 is a front view of the tip of the measurement probe of Modification 1-6. [Figure 12] 10 is a screen example of modified example 1-7. [Figure 13] FIG. 10 is an explanatory diagram illustrating the configuration of a measurement probe and a measurement device according to Modification 1-8. [Figure 14A] FIG. 10 is a cross-sectional view of a connection hub according to a second embodiment. [Figure 14B] 10 is an explanatory diagram illustrating a method of using the connection hub according to the second embodiment. FIG. [Figure 15] FIG. 10 is an explanatory diagram illustrating the configuration of a measurement device according to a third embodiment. [Figure 16] 10 is a time chart illustrating the operation of the measurement device according to the third embodiment. [Figure 17] 10 is a time chart illustrating the operation of the measurement device according to the fourth embodiment. [Figure 18] FIG. 4 is a perspective view of a tip of a measurement probe according to a modified example 4-1. [Figure 19] FIG. 10 is an enlarged cross-sectional view of the tip of an indwelling bladder catheter into which a measurement probe of modification 4-2 has been inserted. [Figure 20] FIG. 10 is an enlarged cross-sectional view of the tip of an indwelling bladder catheter into which a measurement probe of modification 4-3 has been inserted. [Figure 21] FIG. 10 is an explanatory diagram illustrating the configuration of a measurement device according to a fifth embodiment. [Figure 22] 10 is a time chart illustrating the operation of the measurement device according to the fifth embodiment. [Figure 23] FIG. 13 is an explanatory diagram illustrating the configuration of a measurement device according to a sixth embodiment. [Figure 24] FIG. 13 is a cross-sectional view of an indwelling bladder catheter according to a seventh embodiment. [Figure 25] 25 is a view taken along the arrow XXV in FIG. 24. [Figure 26A] FIG. 13 is a cross-sectional view of a connection hub according to a seventh embodiment. [Figure 26B] FIG. 13 is an enlarged cross-sectional view of the tip of an indwelling bladder catheter into which a measurement probe according to a seventh embodiment has been inserted. [Figure 27A] FIG. 26C is a cross-sectional view taken along line XXVIIA-XXVIIA in FIG. 26B. [Figure 27B]FIG. 7 is an enlarged view of the tip of the measurement probe of Modification Example 7-1. [Figure 28A] FIG. 7 is an enlarged cross-sectional view of the tip of the measurement probe of Modification Example 7-2. [Figure 28B] FIG. 7 is an enlarged cross-sectional view of the tip of the measurement probe of Modification Example 7-3. [Figure 29] FIG. 10 is an enlarged cross-sectional view of the tip of an indwelling bladder catheter into which a measurement probe of modification 7-4 has been inserted. [Figure 30A] FIG. 10 is an enlarged cross-sectional view of the tip of an indwelling bladder catheter into which a measurement probe of modification example 7-5 is inserted. [Figure 30B] FIG. 30B is a cross-sectional view taken along line XXXB-XXXB in FIG. 30A. [Figure 31] FIG. 10 is a front view of the tip of an indwelling bladder catheter into which a measurement probe of modification example 7-6 has been inserted. [Figure 32A] FIG. 32 is a cross-sectional view taken along line XXXIIA-XXXIIA in FIG. 31. [Figure 32B] FIG. 32 is a cross-sectional view taken along line XXXIIB-XXXIIB in FIG. 31. [Figure 33] FIG. 2 is a perspective view of the light emitter ring. [Figure 34A] FIG. 10 is an enlarged cross-sectional view of the tip of an indwelling bladder catheter into which a measurement probe of modification 7-7 has been inserted. [Figure 34B] FIG. 34B is a cross-sectional view taken along line XXXIVB-XXXIVB in FIG. 34A. [Figure 35] FIG. 10 is an enlarged cross-sectional view of the tip of an indwelling bladder catheter into which a measurement probe of modification 7-8 has been inserted. [Figure 36A] FIG. 36 is a cross-sectional view taken along line XXXVIA-XXXVIA in FIG. 35. [Figure 36B] FIG. 10 is an explanatory diagram illustrating a method for inserting a measurement probe of Modification Example 7-8 into a probe conduit. [Figure 37A] FIG. 10 is an enlarged cross-sectional view of the tip of an indwelling bladder catheter into which a measurement probe of modification example 7-9 has been inserted. [Figure 37B] FIG. 37B is a cross-sectional view taken along line XXXVIIB-XXXVIIB in FIG. 37A. [Figure 38] FIG. 10 is a cross-sectional view of an indwelling bladder catheter according to variant 7-10. [Figure 39] 39 is a view taken along the arrow XXXIX in FIG. 38. [Figure 40A] 39 is a cross-sectional view taken along line XLA-XLA in FIG. 38. [Figure 40B] 39 is a cross-sectional view taken along line XLB-XLB in FIG. 38. [Figure 41A] FIG. 11 is a cross-sectional view of an indwelling bladder catheter according to variant example 7-11. [Figure 41B] FIG. 10 is a cross-sectional view of an indwelling bladder catheter according to variant 7-12. [Figure 42] FIG. 10 is a cross-sectional view of an indwelling bladder catheter according to variant 7-12. [Figure 43] FIG. 10 is a cross-sectional view of an indwelling bladder catheter according to variant example 7-13. [Figure 44] FIG. 44 is a view taken along arrow XLIV in FIG. [Figure 45] FIG. 44 is a cross-sectional view taken along line XLV-XLV in FIG. 43. [Figure 46A] FIG. 10 is a cross-sectional view of a connection hub according to modification example 7-13. [Figure 46B] FIG. 10 is a cross-sectional view of an indwelling bladder catheter according to variant example 7-14. [Figure 47] FIG. 13 is an explanatory diagram illustrating the configuration of a measurement system according to an eighth embodiment. [Figure 48A] FIG. 10 is a cross-sectional view of a measurement probe with an adapter attached. [Figure 48B] FIG. [Figure 49] FIG. 13 is an explanatory diagram illustrating a method of using the measurement system according to the eighth embodiment. [Figure 50] FIG. 13 is an explanatory diagram illustrating a method of using the measurement system according to the eighth embodiment. [Figure 51] FIG. 13 is an explanatory diagram illustrating the configuration of an indwelling bladder catheter according to a ninth embodiment. [Figure 52A] FIG. 13 is an enlarged cross-sectional view of the tip of the indwelling bladder catheter of the ninth embodiment. [Figure 52B] FIG. 9 is an enlarged cross-sectional view of the tip of an indwelling bladder catheter according to modification example 9-1. [Figure 53A] FIG. 9 is an explanatory diagram illustrating the assembly procedure of the indwelling bladder catheter of modified example 9-1. [Figure 53B] FIG. 9 is an explanatory diagram illustrating the assembly procedure of the indwelling bladder catheter of modified example 9-1. [Figure 54] FIG. 9 is an explanatory diagram illustrating the assembly procedure of the indwelling bladder catheter of modified example 9-1. [Figure 55] FIG. 22 is a functional block diagram of a measurement system according to a tenth embodiment. DETAILED DESCRIPTION OF THE INVENTION

[0008] [Embodiment 1] Fig. 1 is an explanatory diagram illustrating the configuration of a measurement system 10. The measurement system 10 includes an indwelling bladder catheter 15, a measurement probe 14, a connection hub 20, a urine collection bag 17, and a measurement device 30. Fig. 1 is a diagram schematically illustrating each component of the measurement system 10.

[0009] Indwelling bladder catheter 15 includes shaft 153 having side hole 151 and balloon 152 at its tip, and urination funnel 154 connected to one end of shaft 153. Shaft 153 branches into balloon water injection section 169 near urination funnel 154. Urine collection bag 17 includes bag 171, urine collection tube 172, and connecting tube 173. Indwelling bladder catheter 15 and urine collection bag 17 of this embodiment have traditionally been used in medical settings. An overview of how to use a conventional indwelling bladder catheter 15 and urine collection bag 17 will be described.

[0010] A user such as a doctor connects the urination funnel 154 and the connecting tube 173, and then inserts the shaft 153 into the patient's urethra. With the tip of the shaft 153 inside the bladder, the user inflates the balloon 152. The balloon 152 shown in FIG. 1 is in an inflated state. Inflating the balloon 152 prevents the shaft 153 from slipping out of the urethra. The patient's urine passes through the side hole 151, the shaft 153, and the urine collection tube 172 and accumulates in the bag 171.

[0011] In this embodiment, as shown in Figure 1, the connection hub 20 is connected between the urination funnel 154 and the connection tube 173. The patient's urine passes through the side hole 151, the shaft 153, the connection hub 20, and the urine collection tube 172 and accumulates in the bag 171.

[0012] Measuring probe 14 is inserted into indwelling bladder catheter 15 via connection hub 20. As shown by the dashed line in FIG. 1, measuring probe 14 is inserted through almost the entire length of shaft 153, and the tip of measuring probe 14 is located near side hole 151. Measuring probe 14 has optical fiber 41. An optical fiber connector 411 is provided at the rear end of optical fiber 41. The configuration of measuring probe 14 will be described in detail later.

[0013] The measuring device 30 has a display unit 35 and a first connector 371. An optical fiber connector 411 is connected to the first connector 371. The optical fiber 41 is fixed to the urine collection tube 172 at three points with fasteners 49. In the example shown in FIG. 1, the partial pressure of oxygen (pO2) in the patient's urine is displayed on the display unit 35 in real time.

[0014] Fig. 2 is an enlarged cross-sectional view of the tip of indwelling bladder catheter 15 into which measuring probe 14 has been inserted. Fig. 3A is a cross-sectional view taken along line IIIA-IIIA in Fig. 2. Fig. 3B is a cross-sectional view taken along line IIIB-IIIB in Fig. 2. Fig. 4A is an explanatory diagram illustrating the configuration of measuring probe 14.

[0015] 2 and 3A, the shaft 153 is a so-called multi-lumen tube having two channels: a urinary channel 156 and a balloon channel 155. The balloon channel 155 branches off near the urination funnel 154 and passes through the balloon water injection section 169.

[0016] The measurement probe 14 is inserted into the urinary tract 156. As shown in Fig. 2, the balloon duct 155 opens to the inside of the balloon 152, and the tip side of the opening is sealed. The tip of the urinary tract 156 is sealed by a tip member 159. As shown in Fig. 3B, the urinary tract 156 has two side holes 151.

[0017] As shown in Figures 2 and 4A, the measurement probe 14 has the light emitting body 24 and a housing 141 in addition to the optical fiber 41 and optical fiber connector 411 described above. The light emitting body 24 is disposed at the tip of the optical fiber 41. Details of the light emitting body 24 will be described later. The optical fiber 41 is an example of the elongated body of this embodiment. The light emitting body 24 is an example of the sensor of this embodiment.

[0018] 2 and 3B, housing 141 is cylindrical with a portion of the side cut out. The tip of optical fiber 41 is inserted into housing 141. In FIG. 2, the tip of housing 141 abuts against tip member 159. Housing 141 prevents light emitter 24 from moving beyond side hole 151 toward the tip side of indwelling bladder catheter 15. In other words, tip member 159 functions as a protrusion prevention section that prevents measurement probe 14 from protruding from the tip side of indwelling bladder catheter 15.

[0019] That is, housing 141 functions as a sensor holder that holds light-emitting element 24 closer to urination funnel 154 than side hole 151. This configuration keeps light-emitting element 24 in contact with fresh urine that enters urinary tract 156 from side hole 151 and flows toward urination funnel 154. Urinary tract 156 is an example of a flow path in this embodiment. Urine is an example of a fluid that flows through the flow path.

[0020] The light-emitting body 24 is, for example, a translucent resin with a phosphor kneaded therein, and is applied to the end surface of the optical fiber 41 or formed into a sheet and adhered thereto. The phosphor is an example of a fluorescent dye in this embodiment. In this embodiment, a case will be described in which a phosphor that emits fluorescence in response to oxygen in urine is used. The fluorescence is an example of the emitted light emitted by the light-emitting body 24. By analyzing the characteristics of the fluorescence emitted by the phosphor, the oxygen partial pressure and oxygen concentration in urine can be measured in real time.

[0021] This section provides an overview of the measurement method using a fluorophore. When irradiated with excitation light, the fluorophore enters a high-energy excited state. Fluorescence is emitted from the excited fluorophore, and the fluorophore returns to its ground state. The fluorescence characteristics, such as the intensity, phase angle, and decay time of the emitted fluorescence, change depending on the concentration of the quencher with which the fluorophore is in contact. Therefore, the concentration of the quencher can be measured by analyzing the characteristics of the emitted light.

[0022] As described above, this embodiment uses a fluorophore whose fluorescence characteristics change when it comes into contact with oxygen. That is, the quencher in this embodiment is oxygen. By analyzing the fluorescence characteristics in real time, the oxygen partial pressure and oxygen concentration in urine can be measured in real time.

[0023] The emitted light from the phosphor also includes phosphorescence. That is, the measurement may be performed by analyzing the characteristics of phosphorescence. The characteristics of both fluorescence and phosphorescence may be analyzed simultaneously.

[0024] A fluorescent substance that emits fluorescence in response to carbon dioxide in urine may be used. By analyzing the characteristics of the fluorescence, the partial pressure and concentration of carbon dioxide in urine can be measured in real time. A fluorescent substance whose fluorescence characteristics change depending on the hydrogen ion index of urine may be used. By analyzing the characteristics of the fluorescence, the hydrogen ion index of urine, i.e., pH (potential of hydrogen), can be measured in real time.

[0025] A fluorescent substance that emits fluorescence in response to ions such as potassium ions, sodium ions, or chloride ions in urine may be used. By analyzing the characteristics of the fluorescence, the concentration of electrolytes in urine can be measured in real time. In addition, a fluorescent substance that emits fluorescence in response to any component in urine may also be used.

[0026] A fluorophore that reacts similarly to multiple quenchers may be used. For example, a diffusion membrane disposed on the surface of the fluorophore 24 can be used to select the quencher, i.e., the component to be measured, that comes into contact with the fluorophore.

[0027] The fluorescent properties of phosphors change depending on the temperature. By analyzing the fluorescent properties, the temperature of urine can be measured in real time. In other words, by analyzing the properties of the light emitted by the light emitter 24, multiple items such as urine components and urine temperature can be measured simultaneously.

[0028] The side of the optical fiber 41 is preferably covered with a coating (not shown). The coating is preferably a light-shielding body that prevents external light from entering the side of the optical fiber 41. This makes it possible to provide a measurement probe 14 that is protected from the influence of noise due to external light.

[0029] Fig. 4B is a cross-sectional view of the connection hub 20. The connection hub 20 has a hub hard member 21, a hub flexible member 22, a retaining cylinder 213, a retaining rubber 214, and a retaining lid 215. Fig. 5A is a perspective view of the hub hard member 21. Fig. 5B is a perspective view of the hub flexible member 22.

[0030] Hub rigid member 21 has a catheter connection part 218 at one end that can be connected to urination funnel 154. Catheter connection part 218 has a stripe-shaped protrusion to prevent it from coming off. Catheter connection part 218 has dimensions and a shape that allow it to be connected to urination funnel 154 of indwelling bladder catheter 15, similar to the connecting tube 173 of a conventional urine collection bag 17. Inside hub rigid member 21, a first conduit 211 that passes through catheter connection part 218 and a second conduit 212 that branches off from first conduit 211 are provided.

[0031] The hub flexible member 22 is attached to the other end of the hub rigid member 21. The hub flexible member 22 is cylindrical and communicates with the first duct 211. A urine collection bag connection part 228 connectable to the connecting tube 173 is provided on the inner surface of the hub flexible member 22. Striped protrusions are provided on the surface of the urine collection bag connection part 228 to prevent it from coming off. The hub flexible member 22 is made of rubber or elastomer and has rubber elasticity. The urine collection bag connection part 228 has dimensions and a shape that allow it to be connected to the connecting tube 173 of the urine collection bag 17, similar to the urination funnel 154 of a conventional indwelling bladder catheter 15.

[0032] It is more desirable that hub hard member 21 and hub soft member 22 be made of the same material as that used in the connection between existing indwelling bladder catheter 15 and urine collection bag 17. In these existing devices, moldable materials such as polyethylene, polycarbonate, polystyrene, nylon, nylon resin, etc. are used for the hard members, and silicone rubber elastomer, urethane rubber elastomer, etc. are used for the soft members.

[0033] Therefore, the connection hub 20 can be attached between a conventionally used indwelling bladder catheter 15 and a urine collection bag 17. The user can connect the connection hub 20 to an indwelling bladder catheter 15 and a urine collection bag 17 that are appropriately selected depending on the patient's condition, etc.

[0034] The hub hard member 21 and the hub flexible member 22 are fixed together in a watertight manner by, for example, adhesive or screwing. The hub hard member 21 and the hub flexible member 22 may be formed by integral molding of different materials.

[0035] The retaining tube 213 is cylindrical with steps on both the outer and inner diameters at one end, and has a male thread on the outer periphery of the larger diameter part. The retaining rubber 214 is also cylindrical. The retaining lid 215 is a circular box with a through hole in the center of the bottom, and has a female thread on the inner surface of the side wall that engages with the male thread of the retaining tube 213.

[0036] In FIG. 4B , the holding lid 215 is loosened. The through holes provided in the holding lid 215, the holding rubber 214, and the holding tube 213 are connected to the second pipeline 212. After the measurement probe 14 is inserted from the holding lid 215 side, the holding lid 215 is tightened, whereby the holding rubber 214 is compressed and expands in the radial direction. The expanded holding rubber 214 presses against the side surface of the measurement probe 14, fixing it in place. The holding rubber 214 functions as a fixing part in this embodiment, which can fix the measurement probe 14 at any position while it is inserted into the urinary tract 156.

[0037] 6 is a perspective view of fastener 49. Fastener 49 includes a first part 491 and a second part 492. First part 491 has a substantially C-shaped urine collection tube holding part 496. Second part 492 is attached to the outside of urine collection tube holding part 496. Second part 492 has an optical fiber holding part 497 located at the bottom of a slit.

[0038] Urine collection tube holding section 496 has a size that allows it to be fitted onto the outer periphery of urine collection tube 172. Optical fiber holding section 497 has a size that allows it to hold optical fiber 41 pushed through the slit.

[0039] The first material constituting first component 491 is preferably a relatively hard and flexible material, such as hard plastic. The second material constituting second component 492 is preferably an elastomer, such as rubber. The first material may be softer than the second material. First component 491 and second component 492 may be integrally formed from the same material.

[0040] 1, optical fiber 41 is fixed to urine collection tube 172 at multiple locations by fasteners 49. Optical fiber 41 may also be fixed using, for example, medical tape instead of fasteners 49. Optical fiber 41 may also be fixed to any location, such as an IV stand or bed rails.

[0041] 7 is an explanatory diagram illustrating the configuration of the measuring device 30. In addition to a display unit 35 and a first connector 371, the measuring device 30 includes a control unit 31, a main memory device 32, an auxiliary memory device 33, a communication unit 34, an input unit 36, a light source 51, an optical analyzer 52, a light guide 55, a beam splitter 56, and a bus. The control unit 31 is an arithmetic and control device that executes the program of this embodiment. The control unit 31 uses one or more central processing units (CPUs), graphics processing units (GPUs), multi-core CPUs, or the like. The control unit 31 is connected to each hardware unit that constitutes the measuring device 30 via the bus.

[0042] The main memory device 32 is a storage device such as an SRAM (Static Random Access Memory), a DRAM (Dynamic Random Access Memory), a flash memory, etc. The main memory device 32 temporarily stores information required during processing performed by the control unit 31 and programs currently being executed by the control unit 31.

[0043] The auxiliary storage device 33 is a storage device such as an SRAM, flash memory, hard disk, or magnetic tape. The auxiliary storage device 33 stores programs to be executed by the control unit 31 and various data required for executing the programs. The communication unit 34 is an interface that performs communication between the measuring device 30 and a network or other devices.

[0044] Display unit 35 is, for example, a liquid crystal display panel or an organic EL (electro-luminescence) panel. Display unit 35 is attached to the housing of measurement device 30 as shown in FIG. 1. Display unit 35 may be a display device separate from measurement device 30. For example, the screen of another device such as a vital sign monitor may also serve as display unit 35.

[0045] The input unit 36 ​​is a button or the like provided on the housing of the measuring device 30. The display unit 35 and the input unit 36 ​​may be an integrated panel. The first connector 371 is an optical connector to which the optical fiber 41 is connected. The measuring device 30 may be provided with a plurality of first connectors 371.

[0046] The light source 51 is, for example, an LED (light emitting diode) or a laser diode. The light source 51 irradiates the light emitter 24 with excitation light to excite the phosphor contained in the light emitter 24. The excitation light is an example of the irradiation light irradiated from the light source 51 to the light emitter 24. The light emitted by the light source 51 hardly contains any wavelength of the fluorescence emitted by the phosphor.

[0047] The optical analyzer 52 converts the received light into an electrical signal using, for example, a photodiode, and then analyzes the light. The light source 51 and the beam splitter 56, the optical analyzer 52 and the beam splitter 56, and the beam splitter 56 and the first connector 371 are connected by optical guide paths 55, respectively.

[0048] An optical filter that transmits only the wavelength range required to excite the phosphor may be provided midway along the light guide path 55, which is disposed between the light source 51 and the beam splitter 56, or at the end of the light guide path 55. Even when a light source 51 with a wide wavelength range is used, the wavelength range of the excitation light to be irradiated onto the light emitter 24 can be precisely selected. Because noise due to wavelengths other than the excitation light does not occur, a measuring device 30 with high measurement accuracy can be provided.

[0049] An optical lens may be disposed midway along the light guide path 55 or at the end of the light guide path 55. By effectively utilizing the excitation light and fluorescence, it is possible to provide a measuring device 30 with high measurement sensitivity.

[0050] The measurement device 30 may have a second light source that supplies reference light to the optical analyzer 52, in addition to the light source 51 that emits light for excitation light. A measurement device 30 that performs analysis using reference light can be provided. The reference light irradiated from the second light source is directly incident on the optical analyzer 52. The second light source and the optical analyzer 52 are connected by, for example, a dedicated light guide. The second light source and the optical analyzer 52 may be separated by a cavity configured to allow the light irradiated from the second light source to be incident on the optical analyzer 52.

[0051] An overview of how to use the measurement system 10 will be explained using Figure 1. The user connects the indwelling bladder catheter 15, the connection hub 20, and the urine collection bag 17. The user inserts the measurement probe 14 into the indwelling bladder catheter 15 via the connection hub 20. The user can confirm by touch or visually that the housing 141 has butted against the tip member 159.

[0052] The user may slightly pull back measurement probe 14 after confirming that it has hit the target. This prevents the internal measurement probe 14 and tip member 159 from hitting each other too tightly when indwelling bladder catheter 15 is bent. The user then tightens retaining lid 215 to fix measurement probe 14. To determine the optimal position, a marker may be attached to the handle of the measurement probe in advance, or the measurement probe may be configured to have a recess or protrusion that can be fitted structurally so that it can be fixed in the appropriate position.

[0053] Furthermore, the user may retract the measurement probe 14 by a predetermined distance after confirming that it has hit the target. The retaining tube 213, retaining rubber 214, and retaining lid 215 of this embodiment can fix the measurement probe 14 even when the measurement probe 14 is inserted partway into the urinary tract 156. This configuration makes it possible to prevent damage to the measurement probe 14 caused by accidentally grasping a delicate part such as the phosphor 24 together with the shaft 153 with forceps or the like when inserting the shaft 153 into the patient's urethra.

[0054] The user inserts shaft 153 into the patient's urethra. With the tip of shaft 153 inside the bladder, the user inflates balloon 152. In this manner, indwelling bladder catheter 15 is placed in the patient. Urine from the patient passes through side hole 151, urinary tract 156, and urine collection tube 172 and accumulates in bag 171.

[0055] The user connects the optical fiber connector 411 to the first connector 371. The user then fixes the optical fiber 41 to the urine collection tube 172 using the fastener 49.

[0056] The explanation will continue with reference to Figure 7. The user operates the measuring device 30 to activate the light source 51. The excitation light emitted from the light source 51 is irradiated onto the light emitter 24 via the light guide 55, the beam splitter 56, and the optical fiber 41. When the light emitter 24 comes into contact with urine flowing through the urinary tract 156, it emits fluorescence corresponding to the oxygen in the urine. In other words, the light emitter 24 functions as a sensor capable of detecting the oxygen partial pressure and oxygen concentration in the urine.

[0057] The fluorescence enters the beam splitter 56 via the optical fiber 41, the first connector 371, and the light guide path 55. That is, the optical fiber 41 has a function of propagating light irradiated from the light source 51 to the light emitter 24 and light emitted from the light emitter 24. The optical fiber 41 is an example of a light guide of the present embodiment that guides the fluorescence emitted from the light emitter 24. The first connector 371 is an example of a light receiving unit of the present embodiment that receives the fluorescence guided to the optical fiber 41.

[0058] The fluorescent light enters the beam splitter 56 from the first connector 371 through the light guide 55. The beam splitter 56 causes the fluorescent light to enter the light guide 55 connected to the optical analyzer 52. The optical analyzer 52 analyzes the characteristics of the incident fluorescent light and outputs the oxygen partial pressure or oxygen concentration in the urine to the bus in real time. The control unit 31 displays the oxygen partial pressure in the urine output from the optical analyzer 52 on the display unit 35.

[0059] The user may insert the measurement probe 14 into the indwelling bladder catheter 15 after placing the indwelling bladder catheter 15 in the patient. The user can insert the indwelling bladder catheter 15 in a state that is highly flexible and facilitates the insertion procedure.

[0060] For example, if the user observes the patient's condition and determines that it is necessary to measure the oxygen partial pressure in the urine, the user may insert measurement probe 14 into indwelling bladder catheter 15. By connecting connection hub 20 between indwelling bladder catheter 15 and urine collection bag 17, the user can use measurement probe 14 quickly depending on the patient's condition.

[0061] When inserting indwelling bladder catheter 15 into a patient without inserting measurement probe 14, it is desirable that a dummy probe having approximately the same external shape as measurement probe 14 is inserted into holding tube 213 and fixed by holding rubber 214 and holding lid 215. The length of the dummy probe may be long enough to reach partway through second conduit 212.

[0062] Instead of the retaining tube 213, the retaining rubber 214, and the retaining lid 215, a valve that maintains watertightness and airtightness when the measuring probe 14 is not inserted may be attached to the hub rigid member 21. In this way, even when the measuring probe 14 is not inserted, the second conduit 212 remains sealed, thereby preventing the patient's urine from leaking from the second conduit 212 and preventing bacteria and the like from entering the patient's bladder via the second conduit 212 and causing an infection.

[0063] The indwelling bladder catheter 15 and the connection hub 20 may be integrated. Specifically, the urination funnel 154 may function as the connection hub 20. The indwelling bladder catheter 15, the connection hub 20, and the urine collection bag 17 may be supplied to the user in a pre-connected state, that is, a so-called closed system. Furthermore, the indwelling bladder catheter 15 may be supplied to the user with the measurement probe 14 inserted therein.

[0064] 8 is a flowchart illustrating the flow of processing of the program. When the user issues an instruction to operate the light source 51, the control unit 31 starts the program of FIG.

[0065] The control unit 31 turns on the light source 51 (step S501). The light emitter 24 is irradiated with excitation light via the beam splitter 56 and the optical fiber 41. The fluorescence emitted from the phosphor of the light emitter 24 enters the optical analyzer 52 via the optical fiber 41 and the beam splitter 56.

[0066] The optical analyzer 52 outputs urinary oxygen partial pressure data based on the characteristics of the obtained fluorescence. The control unit 31 acquires the urinary oxygen partial pressure data from the optical analyzer 52 (step S502). By step S502, the control unit 31 realizes the function of a data acquisition unit that acquires data from the sensor held in the sensor holding unit.

[0067] 1, the control unit 31 displays the urinary oxygen partial pressure on the display unit 35 (step S503). The control unit 31 determines whether to end the process (step S504). For example, the control unit 31 determines to end the process when an operation to turn off the light source 51 is received or when the optical fiber 41 is removed from the first connector 371.

[0068] If it is determined not to end the process (NO in step S504), the control unit 31 returns to step S502. If it is determined to end the process (YES in step S504), the control unit 31 turns off the light source 51 (step S505). The control unit 31 ends the process.

[0069] According to this embodiment, it is possible to provide a measurement system 10 that can perform measurements without having the tip of the measurement probe 14 protrude from the indwelling bladder catheter 15. For example, even if the patient's posture changes, it is possible to prevent the tip of the measurement probe 14 from damaging the bladder wall.

[0070] According to the present embodiment, light emitter 24 is placed near side hole 151, downstream of side hole 151. Therefore, it is possible to provide measurement system 10 that can measure in real time the oxygen partial pressure and the like in fresh urine that has just been discharged from the bladder into the catheter. Note that the oxygen partial pressure and the like in urine also change while the urine passes through the inside of indwelling bladder catheter 15. By measuring the oxygen partial pressure and the like in fresh urine in real time, it is possible to provide measurement system 10 that can accurately measure changes in oxygen partial pressure.

[0071] Real-time measurement of oxygen tension in urine allows for early detection of signs of acute kidney injury. Compared to conventional methods using urine volume, serum creatine levels, or biomarkers, risk of injury due to kidney hypoxia can be detected at an earlier stage, allowing for appropriate treatment.

[0072] According to this embodiment, it is possible to provide a measurement probe 14 in which the light emitting body 24 is protected by the housing 141. The presence of the housing 141 makes it possible to prevent the light emitting body 24 from coming into contact with the inner surface of the indwelling bladder catheter 15 and the tip member 159, causing damage to the measurement probe 14 and causing it to peel off. It is also possible to prevent damage to the measurement probe 14 from the light emitting body 24 coming into contact with the user's fingers, a medical instrument, or the connection hub 20 when the user inserts the measurement probe 14 into the indwelling bladder catheter 15.

[0073] According to this embodiment, it is possible to provide a measurement probe 14 and a connection hub 20 that can measure the partial pressure of oxygen in urine in real time in combination with an existing indwelling bladder catheter 15 and a urine collection bag 17. A user can select an indwelling bladder catheter 15 based on the patient's condition, past experience, specialized knowledge, etc., and use it in combination with the measurement probe 14 and connection hub 20 of this embodiment.

[0074] By attaching only the connection hub 20 between the indwelling bladder catheter 15 and the urine collection bag 17, it is possible to provide a measurement system 10 in which the measurement probe 14 can be quickly inserted and used when needed. The measurement probe 14 is more expensive than the connection hub 20, but by using it only for patients who need it, medical costs can be reduced.

[0075] For example, when the oxygen partial pressure in urine falls below a threshold, the control unit 31 may notify the user. For example, the control unit 31 may display a message on the display unit 35, or may notify the user by audio output from the measuring device 30. The control unit 31 may send a notification to a nurse's station or the like via a network such as an HIS (Hospital Information System) or EMR (Electronic Medical Records).

[0076] The control unit 31 may calculate an index representing the state of the urinary organs, such as the kidneys, based on the oxygen partial pressure and temperature in the urine, for example, and display the index on the display unit 35. The index representing the state of the urinary organs may be calculated by combining the oxygen partial pressure and temperature in the urine with information acquired from another device, such as a vital sign monitor. The index is not limited to the urinary organs, and may be an index representing the overall state of the patient.

[0077] The optical analyzer 52 is not limited to one having a function of outputting urinary oxygen partial pressure data based on the characteristics of the obtained fluorescence. For example, data indicating the characteristics of the received fluorescence, such as the intensity, phase angle, and decay time, i.e., data before calculating the urinary oxygen partial pressure data, may be output to the bus. In this case, the control unit 31 calculates the urinary oxygen partial pressure or urinary oxygen concentration, etc.

[0078] The optical analysis block, which is made up of the light source 51 , the optical analyzer 52 , the light guide 55 , the beam splitter 56 and the first connector 371 , may be separate from the measurement device 30 .

[0079] When the optical analysis block is a separate unit, the optical analysis block may be combined with a general-purpose information processing device such as a personal computer, tablet, or smartphone to form the measurement device 30 of this embodiment. In this case, the optical analysis block and the information processing device are connected by wire or wirelessly.

[0080] 1 is an example. For example, if the light-emitting body 24 has a phosphor that reacts to potassium ions, the measuring device 30 displays the concentration or amount of potassium ions in urine on the display unit 35 in real time. Furthermore, the phosphor that reacts to potassium ions and the phosphor that reacts to oxygen may be kneaded together into a single structure such as a sheet or into a material that is applied to the tip of the optical fiber 41. This makes it possible to create a system that measures and displays two components simultaneously using a single fiber.

[0081] The measurement probe 14 and the connection hub 20 are preferably single-use products that are supplied to the user in a sterilized state. This reduces the risk of urinary tract infections. A kit that combines one measurement probe 14 and one connection hub 20 may be supplied to the user. A catheter set that combines the measurement probe 14, the connection hub 20, and the indwelling bladder catheter 15 may also be supplied to the user.

[0082] The indwelling bladder catheter 15 is an example of a catheter in this embodiment. Instead of the indwelling bladder catheter 15, the measuring probe 14 and the connection hub 20 may be attached to any tube used to continuously drain body fluids from a patient, such as a chest drainage tube, a peritoneal drainage tube, or a cerebral drainage tube. The measuring probe 14 and the connection hub 20 may be attached to any medical tube used to deliver fluids into a patient's body, such as an infusion tube or a feeding tube. These medical tubes are also examples of catheters in this embodiment.

[0083] [Variation 1-1] This modification relates to a measurement probe 14 that uses a coil 142 instead of a housing 141. Explanation of parts common to the first embodiment will be omitted.

[0084] 9A is a perspective view of the tip of the measurement probe 14 of Modification 1-1. A coil 142 is attached to the tip of an optical fiber 41. The pitch of the coil 142 is several millimeters or less, preventing the user from unintentionally touching the light-emitting body 24.

[0085] This modification provides a measurement probe 14 that is less likely to break even when the measurement probe 14 is pressed against the tip of the indwelling bladder catheter 15 due to a change in the patient's position, etc. In other words, the coil 142 functions as a sensor holder that holds the light-emitting body 24 closer to the urination funnel 154 than the side hole 151.

[0086] [Variation 1-2] This modification relates to a measurement probe 14 in which a coil 142 is provided at the tip of a housing 141. Explanation of parts common to the first embodiment will be omitted.

[0087] Fig. 9B is an explanatory diagram illustrating the configuration of measurement probe 14 of modified example 1-2. The tip of housing 141 is sealed by coil holder 146. Coil 142 is fixed to coil holder 146. Fig. 9B shows the tip side of coil 142 in a perspective view and the other parts in a cross-sectional view.

[0088] According to this modification, it is relatively easy to manufacture the measurement probe 14 having the coil 142 at its tip. In this modification, the housing 141 and the coil 142 function as a sensor holder that holds the light-emitting element 24 closer to the urination funnel 154 than the side hole 151.

[0089] [Variation 1-3] This modification relates to a measurement probe 14 that uses a sheet-like cover plate 143 instead of the housing 141. Explanation of parts common to the first embodiment will be omitted.

[0090] 9C is a perspective view of the tip of the measurement probe 14 of Modification 1-3. A sheet-like cover plate 143 bent into a substantially U-shape is attached to the tip of the optical fiber 41 by a holding tube 147.

[0091] The cover plate 143 is made by, for example, bending a resin sheet. The cover plate 143 may also be made by cutting a rod that has been extruded to have a U-shaped cross section. The holding tube 147 is, for example, a heat-shrinkable tube. Instead of using the holding tube 147, the cover plate 143 may be fixed to the optical fiber 41 by wrapping adhesive tape around it. The holding tube 147 may cover the joint surface between the light emitter 24 and the optical fiber 41 and the side surface of the light emitter 24.

[0092] This modification provides a measurement probe 14 with a simple configuration that protects the light-emitting body 24. The cover plate 143 functions as a sensor holder that holds the light-emitting body 24 on the urination funnel 154 side of the side hole 151.

[0093] [Variation 1-4] This modification relates to a measurement probe 14 that uses a wire 144 instead of a housing 141. Explanation of parts common to the first embodiment will be omitted.

[0094] Fig. 10A is a perspective view of the tip of measurement probe 14 of modified example 1-4. Fig. 10B is a cross-sectional view taken along line XB-XB in Fig. 10A. A two-layer tube, consisting of a protective tube 148 and a holding tube 147, is attached to the tip of optical fiber 41. Wire 144 is sandwiched between protective tube 148 and holding tube 147.

[0095] The protective tube 148 covers the tip of the optical fiber 41 as well as the side of the light emitter 24. The holding tube 147 is shorter than the protective tube 148. Although not shown, the protective tube 148 and the holding tube 147 are arranged at multiple locations over the entire length of the optical fiber 41, and fix the wire 144 along the optical fiber 41.

[0096] According to this modification, protective tube 148 is disposed between optical fiber 41 and wire 144, thereby preventing optical fiber 41 from being damaged by wire 144. Because wire 144 is disposed along optical fiber 41, buckling or the like is less likely to occur when optical fiber 41 is inserted into indwelling bladder catheter 15, and measurement probe 14 can be provided that is easy for the user to handle. Wire 144 functions as a sensor holder that holds light-emitting element 24 on the urination funnel 154 side of side hole 151.

[0097] [Variation 1-5] This modification relates to a measurement probe 14 equipped with a temperature sensor 45. Explanation of parts common to modifications 1-4 will be omitted.

[0098] 11A is a perspective view of the tip of the measurement probe 14 of Modification Example 1-5. A temperature sensor 45 is fixed near the light-emitting body 24. The temperature sensor 45 is, for example, a resistance temperature detector, a thermistor, or a thermocouple. The cable of the temperature sensor 45 is fixed to the optical fiber 41 together with the wire 144.

[0099] The temperature sensor 45 is connected to a temperature measuring device (not shown). The measuring device 30 may have a built-in temperature measuring device.

[0100] This modification provides a measurement system 10 that can measure temperature using a temperature sensor 45 that is independent of the light-emitting body 24. For example, by using the temperature measured using the temperature sensor 45 to correct the measurement results measured using the light-emitting body 24, a measurement device 30 that can perform highly accurate measurements can be provided.

[0101] [Variation 1-6] This modification relates to a measurement probe 14 in which a plurality of openings are provided in a housing 141. Explanation of parts common to the first embodiment will be omitted.

[0102] 11B is a front view of the tip of measurement probe 14 of modification 1-6. Housing 141 of this modification is a pipe with multiple holes. Note that while FIG. 11B shows a case where the holes are circular, the holes may be any shape, such as oval or rectangular.

[0103] According to this modification, it is possible to provide a measurement system 10 in which the measurement results are less likely to be affected even when the measurement probe 14 rotates inside the indwelling bladder catheter 15.

[0104] [Variation 1-7] This modification relates to a measurement device 30 that displays time-series data on a display unit 35. Explanation of parts common to the first embodiment will be omitted.

[0105] 12 is an example of a screen of Modification 1-7. In this modification, the measuring device 30 measures the oxygen partial pressure and the temperature in real time. The measuring device 30 of this modification has a relatively large display unit 35.

[0106] The screen displays an index field 67, a date and time field 61, an oxygen partial pressure field 62, a temperature field 63, and a graph field 68. The index field 67 displays an index showing the state of the kidneys. The combination of letters and the "+" or "-" symbols allows the user to easily understand the state of the patient's kidneys.

[0107] The date and time column 61 displays the date, day of the week, and time. The oxygen partial pressure column 62 displays the oxygen partial pressure in urine. The temperature column 63 displays the temperature. The graph column 68 displays time series data for the oxygen partial pressure in urine and the temperature as line graphs. In the graph column 68, the dashed line indicates the time series data for the oxygen partial pressure in urine, and the solid line indicates the time series data for the temperature. The dashed line displayed below the word "pO2" in the oxygen partial pressure column 62 and the solid line displayed below the word "temperature" function as a so-called legend column. The user can easily understand what each graph means.

[0108] The line graph shown in the graph field 68 is an example of a graph format. Any graph format that is easy for the user to use in clinical practice can be used in the graph field 68. For example, if the value per unit time is important, a bar graph can be used to display in the graph field 68. The user may be able to specify the graph format as appropriate.

[0109] The time-series data may be displayed in a table format instead of a graph format. The control unit 31 may also accept user settings changes to the items and layout displayed on the display unit 35. The user can use the measurement system 10 with settings that are easy to use depending on the situation.

[0110] [Variation 1-8] This modification relates to a measuring probe 14 in which the optical fiber 41 is divided into a fiber for irradiating light and a fiber for receiving light. Explanation of parts common to the first embodiment will be omitted.

[0111] 13 is an explanatory diagram illustrating the configuration of the measurement probe 14 and the measurement device 30 of Modification 1-8. The optical fiber 41 of the measurement probe 14 is divided into two bundles at the end, with a fluorescent connector 413 connected to one bundle and an illumination light connector 414 connected to the other bundle.

[0112] The measurement device 30 includes a second connector 372 and a third connector 373 instead of the first connector 371. The second connector 372 is connected to the optical analyzer 52 via the light guide path 55. The third connector 373 is connected to the light source 51 via the light guide path 55.

[0113] The excitation light emitted from the light source 51 irradiates the light emitter 24 via the light guide 55, the third connector 373, and the illumination light connector 414. The fluorescence emitted from the light emitter 24 enters the optical analyzer 52 via the optical fiber 41, the fluorescence connector 413, the second connector 372, and the light guide 55.

[0114] It is desirable that the fiber connected to the illumination light connector 414 has specifications suitable for the propagation of excitation light, and that the fiber connected to the fluorescence connector 413 has specifications suitable for the propagation of fluorescence.

[0115] An optical connector for connecting one bundle of fibers and two bundles of fibers may be used at a branching section that branches one bundle of optical fibers 41 into two bundles.

[0116] [Embodiment 2]

[0117] This embodiment relates to a measurement system 10 that is suitable for performing measurements at the junction of a first pipeline 211 and a second pipeline 212. Explanation of parts common to the first embodiment will be omitted.

[0118] 14A is a cross-sectional view of the connection hub 20 of the second embodiment. The first conduit 211 has a large-diameter portion on the catheter connection portion 218 side and a small-diameter portion on the hub flexible member 22 side. A tapered portion 216 is provided at the boundary between the large-diameter portion and the small-diameter portion. The second conduit 212 opens into the tapered surface of the tapered portion 216. No retaining tube 213 is attached to the second conduit 212.

[0119] FIG. 14B is an explanatory diagram illustrating how to use the connection hub 20 according to the second embodiment. In this embodiment, a retaining rubber 214 is fixed to the optical fiber 41. A user can secure the optical fiber 41 by inserting the optical fiber 41 into the second conduit 212 and pushing the retaining rubber 214 into the stepped portion at the end of the second conduit 212. The retaining rubber 214 fulfills the function of the fixing portion in this embodiment, which can fix the measurement probe 14 while it is inserted into the second conduit 212. Furthermore, the structure that serves as the retaining rubber 214 is not limited to rubber. It is also possible to fix the optical fiber 41 directly with an adhesive, or to fix the optical fiber 41 by using a structure in which a metal member is externally crimped.

[0120] The light emitter 24 fixed to the tip of the optical fiber 41 is disposed in a tapered section 216 provided in the first duct 211. By disposing the light emitter 24 at a location where the flow path of the introduced urine narrows, it is possible to provide a measurement system 10 in which the light emitter 24 reliably comes into contact with the urine.

[0121] 14B, i.e., in the middle of the large diameter portion, a check valve for preventing backflow of urine may be provided. Preventing backflow of urine from bag 171 to the bladder can reduce the risk of developing a urinary tract infection.

[0122] As in the first embodiment, a holding tube 213, a holding rubber 214, and a holding lid 215 may be provided at the end of the second conduit 212. Depending on the condition of the patient, the user may place the light emitting body 24 in the tapered portion 216, or may place the light emitting body 24 at a position closer to the tip of the indwelling bladder catheter 15 than the tapered portion 216.

[0123] [Embodiment 3] This embodiment relates to a measuring device 30 that includes a filter 57 that separates excitation light and fluorescence. Explanation of parts common to the first embodiment will be omitted.

[0124] 15 is an explanatory diagram illustrating the configuration of the measurement device 30 according to the third embodiment. A filter 57 is disposed between the beam splitter 56 and the first connector 371 via a light guide path 55. The control unit 31 is capable of adjusting the wavelength range of light transmitted by the filter 57. The light source 51 according to the present embodiment emits a broadband light that includes the wavelength of the fluorescence in addition to the wavelength of the excitation light. The light source 51 is, for example, a white LED.

[0125] FIG. 16 is a time chart explaining the operation of the measurement device 30 of embodiment 3. FIG. 16A shows the ON and OFF timing of the light source 51. FIG. 16B shows the operation timing of the filter 57. b1 indicates that the filter 57 transmits excitation light. b2 indicates that the filter 57 transmits fluorescence. FIG. 16C shows the operation timing of the optical analyzer 52. ON indicates an operation in which the characteristics of the fluorescence are analyzed. OFF indicates an operation in which the characteristics of the fluorescence are not analyzed. The horizontal axes in all of FIG. 16A to FIG. 16C indicate time.

[0126] During the period from time t1 to time t2, the light source 51 is in an ON state. During this period, the filter 57 transmits the excitation light. The optical analyzer 52 does not operate. The excitation light irradiates the light emitter 24. When the light emitter 24 is in contact with urine, it emits fluorescence according to the state of the urine.

[0127] During the period from time t2 to t3, light source 51 is in the OFF state. During this period, filter 57 transmits the fluorescent light. Optical analyzer 52 analyzes the characteristics of the fluorescent light and outputs the oxygen partial pressure in the urine to the bus. The same operation is repeated after time t3.

[0128] According to this embodiment, it is possible to provide a measurement system 10 that can perform accurate measurements even when the light emitted by the light source 51 contains fluorescent wavelengths.

[0129] [Embodiment 4] This embodiment relates to a measurement system 10 that can simultaneously measure a plurality of items using one light source 51. Explanation of parts common to the third embodiment will be omitted.

[0130] In this embodiment, two types of phosphors are mixed into the light-emitting body 24. That is, in this embodiment, two types of sensors are fixed to the tip of a bundle of optical fibers 41. In the following description, the two types of phosphors will be referred to as phosphor J and phosphor K. The wavelengths of the fluorescence emitted by phosphor J and phosphor K are sufficiently different from each other.

[0131] Figure 17 is a time chart explaining the operation of the measuring device 30 of embodiment 4. Figure 17A shows the ON and OFF timing of the light source 51. Figure 17B shows the operation timing of the filter 57. b1j indicates that the filter 57 transmits the excitation light of phosphor J. b2j indicates that the filter 57 transmits the fluorescence emitted by phosphor J. b1k indicates that the filter 57 transmits the excitation light of phosphor K. b2k indicates that the filter 57 transmits the fluorescence emitted by phosphor K.

[0132] Fig. 17C shows the timing at which optical analyzer 52 operates. cj indicates an operation for analyzing the characteristics of the fluorescence emitted by phosphor J. ck indicates an operation for analyzing the characteristics of the fluorescence emitted by phosphor K. OFF indicates an operation for not analyzing the characteristics of the fluorescence. The horizontal axes in Figs. 17A to 17C all indicate time.

[0133] During the period from time t1 to time t2, the light source 51 is in an ON state. During this period, the filter 57 transmits the excitation light of the phosphor J. The optical analyzer 52 does not operate. The excitation light irradiates the light-emitting body 24. When the light-emitting body 24 is in contact with urine, the phosphor J emits fluorescence according to the state of the urine.

[0134] During the period from time t2 to time t3, light source 51 is in the OFF state. During this period, filter 57 transmits the fluorescent light emitted by phosphor J. Light analyzer 52 analyzes the characteristics of the fluorescent light and outputs items related to phosphor J to the bus.

[0135] During the period from time t3 to time t4, the light source 51 is in the ON state. During this period, the filter 57 transmits the excitation light of the phosphor K. The optical analyzer 52 does not operate. The excitation light irradiates the light-emitting body 24. When the light-emitting body 24 is in contact with urine, the phosphor K emits fluorescence according to the state of the urine.

[0136] During the period from time t4 to time t5, light source 51 is in the OFF state. During this period, filter 57 transmits the fluorescence emitted by phosphor K. Light analyzer 52 analyzes the characteristics of the fluorescence and outputs items related to phosphor K to the bus. The same operation is repeated from time t6 onwards.

[0137] This embodiment provides a measurement system 10 that can measure multiple items using a single light source 51. The light emitter 24 may include three or more types of phosphors. The filter 57 sequentially transmits the excitation light and fluorescence of each phosphor.

[0138] [Variation 4-1] 18 is a perspective view of the tip of the measurement probe 14 of Modification 4-1. In this modification, a first light-emitting body 241 mixed with a fluorescent material K and a second light-emitting body 242 mixed with a fluorescent material J are disposed on the end face of the optical fiber 41.

[0139] 18 shows an example in which the first light emitter 241 and the second light emitter 242 are both semicircular, the first light emitter 241 and the second light emitter 242 may be arranged concentrically. The size of the first light emitter 241 and the size of the second light emitter 242 may be different.

[0140] 18 may have an optical fiber connector 411 connected to a fiber bundle that guides light emitted from a first light emitter 241, and an optical fiber connector 411 connected to a fiber bundle that guides light emitted from a second light emitter 242. The two optical fiber connectors 411 can be connected to separate measuring devices 30 for use.

[0141] [Variation 4-2] This modification relates to a measurement probe 14 in which light emitters 24 are arranged at different positions along the longitudinal direction of an optical fiber 41.

[0142] 19 is an enlarged cross-sectional view of the tip of indwelling bladder catheter 15 into which measurement probe 14 of modification 4-2 has been inserted. A first light emitter 241 is disposed on the end face of optical fiber 41, and a second light emitter 242 is disposed midway through optical fiber 41. Second light emitter 242 has a ring shape that surrounds optical fiber 41 connected to first light emitter 241.

[0143] [Variation 4-3] 20 is an enlarged cross-sectional view of the tip of indwelling bladder catheter 15 into which measurement probe 14 of modification 4-3 has been inserted. A short branch is provided midway through optical fiber 41, and second light emitter 242 is disposed on the end face of the branch.

[0144] [Embodiment 5] This embodiment relates to a measurement system 10 that uses a light source 51 that switches between and emits multiple narrowband excitation lights. Explanation of parts common to embodiment 3 will be omitted. Figure 21 is an explanatory diagram illustrating the configuration of a measurement device 30 according to embodiment 5. In this embodiment, a filter 57 is disposed between a beam splitter 56 and an optical analyzer 52.

[0145] Fig. 22 is a time chart illustrating the operation of the measurement device 30 according to the fifth embodiment. Fig. 22A shows the timing at which the light source 51 operates. aj indicates that the light source 51 emits excitation light for phosphor J. ak indicates that the light source 51 emits excitation light for phosphor K.

[0146] 22B shows the timing of the operation of filter 57. ALL indicates that filter 57 transmits all light. bj indicates that filter 57 transmits the fluorescence emitted by phosphor J. bk indicates that filter 57 transmits the fluorescence emitted by phosphor K.

[0147] Fig. 22C shows the timing at which optical analyzer 52 operates. cj indicates an operation for analyzing the characteristics of the fluorescence emitted by phosphor J. ck indicates an operation for analyzing the characteristics of the fluorescence emitted by phosphor J. OFF indicates an operation for not analyzing the characteristics of the fluorescence. The horizontal axes in Figs. 22A to 22C all indicate time.

[0148] During the period from time t1 to time t2, the light source 51 emits excitation light that excites the phosphor J. During this period, the filter 57 transmits all light. The optical analyzer 52 does not operate. The excitation light irradiates the light-emitting body 24. When the light-emitting body 24 is in contact with urine, the phosphor J emits light according to the state of the urine.

[0149] During the period from time t2 to time t3, light source 51 is in the OFF state. During this period, filter 57 transmits the fluorescence emitted by phosphor J. Light analyzer 52 analyzes the characteristics of the fluorescence emitted by phosphor J and outputs the results to the bus.

[0150] During the period from time t3 to time t4, the light source 51 emits excitation light that excites the phosphor K. During this period, the filter 57 transmits all light. The optical analyzer 52 does not operate. The excitation light irradiates the light-emitting body 24. When the light-emitting body 24 is in contact with urine, the phosphor K emits light according to the state of the urine.

[0151] During the period from time t4 to time t5, light source 51 is in the OFF state. During this period, filter 57 transmits the fluorescence emitted by phosphor K. Optical analyzer 52 analyzes the characteristics of the fluorescence emitted by phosphor K and outputs the results to the bus. The same operation is repeated after time t5.

[0152] This embodiment provides a measurement system 10 that can measure multiple items using one light source 51 and one light emitter 24. The light emitter 24 may have three or more types of phosphors. The filter 57 sequentially switches the wavelength of light to be transmitted according to each phosphor.

[0153] The light source 51 may emit broadband light that includes both the excitation light for phosphor J and the excitation light for phosphor K. For example, the light source 51 may emit white light. In this case, both aj and ak in FIG. 22A indicate that the light source 51 is in the ON state.

[0154] [Embodiment 6] This embodiment relates to a measurement device 30 that includes a plurality of optical analyzers 52. Explanation of parts common to the fifth embodiment will be omitted.

[0155] 23 is an explanatory diagram illustrating the configuration of a measurement apparatus 30 according to embodiment 6. The measurement apparatus 30 includes two optical analyzers 52, a first optical analyzer 521 and a second optical analyzer 522, and two beam splitters 56, a first beam splitter 561 and a second beam splitter 562.

[0156] A first beam splitter 561 is connected between the light source 51 and the first connector 371. A second beam splitter 562 is connected between the first beam splitter 561 and the first and second optical analyzers 521 and 522. The second beam splitter 562 is a dichroic beam splitter that separates incident light based on wavelength. The second beam splitter 562 functions as a spectroscopic section that separates fluorescence emitted from multiple phosphors.

[0157] In the following description, an example will be described in which the first light analyzer 521 analyzes the characteristics of the fluorescence emitted from phosphor J, and the second light analyzer 522 analyzes the characteristics of the fluorescence emitted from phosphor K. The light source 51 emits excitation light capable of exciting both phosphor J and phosphor K.

[0158] It should be noted that the phosphor J and the phosphor K are mixed, for example, into one light-emitting body 24. When the measurement probe 14 has a plurality of light-emitting bodies 24, namely, a first light-emitting body 241 and a second light-emitting body 242, as described with reference to Figs. 18 to 20, the phosphor J may be mixed into one light-emitting body 24, and the phosphor K may be mixed into the other light-emitting body 24.

[0159] The excitation light irradiates the light emitter 24 via the light guide 55, the beam splitter 56, and the optical fiber 41. When the light emitter 24 comes into contact with urine flowing through the urinary tract 156, the phosphors J and K each emit fluorescence.

[0160] The fluorescence emitted by phosphor J and phosphor K is mixed and enters optical fiber 41. The fluorescence guided by optical fiber 41 enters first beam splitter 561 via first connector 371 and light guide path 55. The first beam splitter 561 causes the fluorescence to enter light guide path 55 connected to second beam splitter 562. The second beam splitter 562 separates the fluorescence into the fluorescence emitted by phosphor J and other light. The fluorescence emitted by phosphor J enters first optical analyzer 521, and the other light enters second optical analyzer 522.

[0161] The first optical analyzer 521 analyzes the characteristics of the fluorescence emitted by phosphor J and outputs the results to the bus. The second optical analyzer 522 analyzes the characteristics of the fluorescence emitted by phosphor K and outputs the results to the bus. An optical filter that transmits only the fluorescence emitted by phosphor K may be disposed between the second beam splitter 562 and the second optical analyzer 522.

[0162] This embodiment provides a measurement system 10 that simultaneously analyzes fluorescence emitted by two types of phosphors. Note that the light emitter 24 may include three or more types of phosphors, and the measurement device 30 may include optical analyzers 52 and beam splitters 56 corresponding to the number of phosphors. In order to adjust the wavelength of light passing through the light guide path 55 to an arbitrary wavelength, an optical filter that passes only specific wavelengths may be disposed midway along the light guide path 55.

[0163] [Embodiment 7] This embodiment relates to a measurement system 10 using an indwelling bladder catheter 15 having a probe channel 157 arranged parallel to a urinary tract 156. Explanation of parts common to the first embodiment will be omitted.

[0164] Figure 24 is a cross-sectional view of indwelling bladder catheter 15 of embodiment 7. Figure 25 is a view taken along arrow XXV in Figure 24. Shaft 153 of this embodiment is a so-called multi-lumen tube having three channels: urinary channel 156, balloon channel 155, and probe channel 157.

[0165] The probe channel 157 communicates with the urinary tract 156 midway through the indwelling bladder catheter 15. The urinary tract 156 and the probe channel 157 each open at the end face of the shaft 153 on the hub flexible member 22 side.

[0166] 26A is a cross-sectional view of connection hub 20 according to embodiment 7. Two independent conduits, a first conduit 211 and a second conduit 212, are provided within connection hub 20. That is, in this embodiment, first conduit 211 and second conduit 212 do not merge with each other.

[0167] Fig. 26B is an enlarged cross-sectional view of the tip of indwelling bladder catheter 15 into which measuring probe 14 of embodiment 7 is inserted. Fig. 27A is a cross-sectional view taken along line XXVIIA-XXVIIA in Fig. 26B.

[0168] As shown in Figure 26B, the partition between probe duct 157 and urinary tract 156 has been removed from the tip of indwelling bladder catheter 15 to the middle of side hole 151. Measuring probe 14 is inserted into probe duct 157. Light emitter 24 provided at the tip of measuring probe 14 is located near side hole 151. Retaining rubber 214 realizes the function of the fixing part in this embodiment, which can fix measuring probe 14 in a state where it is inserted into probe duct 157.

[0169] According to this embodiment, measurement probe 14 is inserted into probe duct 157, which has a smaller diameter than urinary tract 156, so that even if the shape of shaft 153 changes, there is little change in the position between the tip of measurement probe 14 and the tip of indwelling bladder catheter 15. Therefore, it is possible to provide measurement system 10 in which measurement probe 14 is less likely to be pressed against the tip of indwelling bladder catheter 15 even if the patient's position changes, etc.

[0170] At the tip of the measurement probe 14, a sensor holding portion such as the housing 141, coil 142, cover plate 143 or wire 144 described in embodiment 1 and its variations is provided, and may be butted against the tip member 159.

[0171] The partition between the probe duct 157 and the urinary tract 156 may be removed up to the urination funnel 154 side of the side hole 151. In this case, the light emitter 24 can be positioned closer to the urination funnel 154 side of the side hole 151. By ensuring that fresh urine comes into contact with the light emitter 24, a measurement system 10 that can perform even more accurate measurements can be provided.

[0172] The measuring probe 14 and the indwelling bladder catheter 15 are preferably single-use products that are supplied to the user in a sterilized state. A catheter set that combines the measuring probe 14 and the indwelling bladder catheter 15 may also be supplied to the user.

[0173] [Variation 7-1] 27B is an enlarged view of the tip of the measurement probe 14 of Modification 7-1. In this modification, the light-emitting body 24 formed in a sheet shape is fixed to the end face of the optical fiber 41 via an adhesive layer 249.

[0174] The light-emitting body 24 is, for example, a plate made of a translucent resin into which a phosphor is kneaded. The light-emitting body 24 may also be a translucent plate coated with a phosphor. By using an adhesive with a short curing time for the adhesive layer 249, it is possible to provide a measurement probe 14 that can be manufactured in a short time. In addition, a layer for preventing deterioration of the dye due to ambient light may be formed on the surface of the light-emitting body 24. By coating or separately forming a layer containing carbon black or the like on the surface of the light-emitting body 24 in the form of a plate, it is possible to prevent the phosphor 24 from being exposed to unnecessary light.

[0175] [Variation 7-2] 28A is an enlarged cross-sectional view of the tip of the measurement probe 14 of Modification 7-2. In this modification, the end of the optical fiber 41 is covered with the light emitting body 24.

[0176] For example, the optical fiber 41 of this modified example can be manufactured by immersing the tip of the optical fiber 41 in uncured transparent resin in which the phosphor is mixed, and then curing the resin after pulling it up. The transparent resin in which the phosphor is mixed may be molded onto the tip of the optical fiber 41 using a mold.

[0177] [Variation 7-3] 28B is an enlarged cross-sectional view of the tip of the measurement probe 14 of Modification 7-3. In this modification, a plate-shaped light emitter 24 is fixed to the end face of the optical fiber 41 substantially perpendicularly.

[0178] A light guide 248 made of, for example, a light-transmitting resin is disposed between the end of the optical fiber 41 and the light emitter 24. The optical fiber 41, the light guide 248, and the light emitter 24 are bonded and fixed together by an adhesive layer (not shown). The light guide 248 may also serve as the adhesive layer that bonds and fixes the optical fiber 41 and the light emitter 24. The light guide 248 may also be formed into the shape shown in FIG. 28B by polishing or shaping the optical fiber 41.

[0179] [Variation 7-4] Figure 29 is an enlarged cross-sectional view of the tip of an indwelling bladder catheter 15 into which a measurement probe 14 of variation 7-4 has been inserted. In this variation, a through-hole provided in a tip member 159 communicates with a probe duct 157. The light-emitting body 24 is disposed near the tip member 159 and can come into contact with fresh urine in the bladder. By determining the insertion length at the proximal portion where the optical fiber 41 is inserted, it is possible to prevent the light-emitting body 24 from protruding from the tip of the catheter. Positioning is performed with the expectation that the light-emitting body 24 may protrude if the catheter is bent.

[0180] 29, since the probe duct 157 and the shaft 153 are connected near the tip of the indwelling bladder catheter 15, urine in the bladder flows into the urinary tract 156 through the gap between the probe duct 157 and the measuring probe 14 in addition to the side hole 151. Therefore, fresh urine is likely to come into contact with the light-emitting body 24.

[0181] [Variation 7-5] Figure 30A is an enlarged cross-sectional view of the tip of indwelling bladder catheter 15 into which measurement probe 14 of modification 7-5 has been inserted. Figure 30B is a cross-sectional view taken along line XXXB-XXXB in Figure 30A. In this modification, the tip of probe conduit 157 is sealed with light-emitting body 24. Measurement probe 14 inserted into probe conduit 157 does not have light-emitting body 24 at the end of optical fiber 41.

[0182] When the light emitter 24 comes into contact with the quencher contained in the urine that has flowed in from the side hole 151, it emits fluorescence. The fluorescence propagates to the measurement device 30 via the optical fiber 41. The end face of the optical fiber 41 may be abutted against the light emitter 24, or there may be a gap between the end face and the light emitter 24. To ensure optical stability, an optical lens made of soft resin may be present between the light emitter 24 and the optical fiber 41.

[0183] [Variation 7-6] Fig. 31 is a front view of the tip of indwelling bladder catheter 15 into which measurement probe 14 of modification example 7-6 has been inserted. Fig. 32A is a cross-sectional view taken along line XXXIIA-XXXIIA in Fig. 31. Fig. 32B is a cross-sectional view taken along line XXXIIB-XXXIIB in Fig. 31.

[0184] In this modified example, an illuminant ring 245 is fitted into the inner surface of the side hole 151. Figure 33 is a perspective view of the illuminant ring 245. The illuminant ring 245 is in the shape of a semi-cylindrical ring with a through-hole formed in the middle. The illuminant ring 245 has an illuminant 24 and a non-light-emitting portion 244. The illuminant 24 is, for example, a translucent resin with a fluorescent material kneaded into it. The non-light-emitting portion 244 is the same translucent resin as the base material of the illuminant 24.

[0185] 31 and 32A, the light-emitting element ring 245 is attached so that the light-emitting element 24 faces the urination funnel 154. As shown in FIG. 32B, the light-emitting element 24 closes the end of the probe channel 157.

[0186] When the light emitter 24 comes into contact with the quencher contained in the urine, it emits fluorescence. The fluorescence is transmitted to the measuring device 30 via the optical fiber 41. The end face of the optical fiber 41 may be abutted against the light emitter 24, or there may be a gap between the end face and the light emitter 24.

[0187] According to this modification, the light emitting body ring 245 and the shaft 153 can be bonded to each other over the entire circumference of the inner surface of the side hole 151, thereby achieving strong bonding. By using the same resin material for the base material of the light emitting body 24 and the non-light emitting portion 244, it is possible to prevent peeling between the light emitting body 24 and the non-light emitting portion 244. Note that the entire light emitting body ring 245 may be formed from the light emitting body 24.

[0188] [Variation 7-7] Fig. 34A is an enlarged cross-sectional view of the tip of indwelling bladder catheter 15 into which measurement probe 14 of modification 7-7 is inserted. Fig. 34B is a cross-sectional view taken along line XXXIVB-XXXIVB in Fig. 34A.

[0189] In this modification, a plate-shaped light emitter 24 is disposed between a urinary tract 156 and a probe conduit 157. A light guide portion 248 having a substantially prism shape is attached to the end of an optical fiber 41.

[0190] The light emitter 24 emits fluorescence when it comes into contact with urine that has entered the urinary tract 156 through the side hole 151. The fluorescence is guided to the optical fiber 41 by the light guiding section 248. According to this modification, the fluorescence emitted from the light emitter 24, which has an area larger than the end face of the optical fiber 41, is guided to the optical fiber 41 by the light guiding section 248, thereby providing a measurement system 10 with high sensitivity.

[0191] [Variation 7-8] Figure 35 is an enlarged cross-sectional view of the tip of indwelling bladder catheter 15 into which measurement probe 14 of modification 7-8 has been inserted. Figure 36A is a cross-sectional view taken along line XXXVIA-XXXVIA in Figure 35. Optical fiber 41 of this modification is formed so that the tip is folded back, and light-emitting element 24 is disposed on the end face.

[0192] 36B is an explanatory diagram illustrating a method for inserting measurement probe 14 of modification 7-8 into probe conduit 157. Measurement probe 14 is inserted into probe conduit 157 with the long axis of probe conduit 157, which has an oval cross section, aligned with the folding back direction of optical fiber 41. After measurement probe 14 is inserted until the folded back portion hits tip member 159, measurement probe 14 is rotated approximately 90 degrees to reach the state shown in FIGS. 35 and 36A.

[0193] According to this modification, the light-emitting body 24 of the measurement probe 14 inserted into the small-diameter probe duct 157 can be placed inside the urinary tract 156. Therefore, it is possible to provide a measurement system 10 in which the light-emitting body 24 comes into contact with fresh urine.

[0194] [Variation 7-9] Figure 37A is an enlarged cross-sectional view of the tip of indwelling bladder catheter 15 into which measurement probe 14 of variation 7-9 has been inserted. Figure 37B is a cross-sectional view taken along line XXXVIIB-XXXVIIB in Figure 37A. In this variation, light-emitting block 246 is disposed on the inner surface of the tip of indwelling bladder catheter 15. Light-emitting element 24 is disposed on the surface of light-emitting element block 246. Fluorescence emitted by light-emitting element 24 in contact with urine is guided in an approximately U-shape as shown by the arrow in Figure 37A and enters the end face of optical fiber 41.

[0195] The light emitting block 246 is, for example, formed by bending an optical fiber bundle into a U-shape. The light emitting block 246 may be a combination of a plurality of optical components such as a light guide and a prism.

[0196] [Variation 7-10] Figure 38 is a cross-sectional view of indwelling bladder catheter 15 of modification examples 7-10. Figure 39 is a view seen from the arrow XXXIX in Figure 38. Figure 40A is a cross-sectional view taken along line XLA-XLA in Figure 38. Figure 40B is a cross-sectional view taken along line XLB-XLB in Figure 38.

[0197] In this modification, the shaft 153 is a multi-lumen tube having three channels: a balloon channel 155, a urinary channel 156, and a probe channel 157. The urinary channel 156 has a generally semi-cylindrical cross section. The balloon channel 155 and the probe channel 157 are arranged in parallel on the upper side of FIGS. 38 to 40B. As shown in FIG. 40B, the balloon channel 155 opens to the inside of the balloon 152.

[0198] [Variation 7-11] Figure 41A is a cross-sectional view of an indwelling bladder catheter 15 of variant 7-11. Figure 41A shows a cross section at the same position as Figure 40B. In this variant, shaft 153 is a multi-lumen tube having three channels: balloon channel 155, urinary channel 156, and probe channel 157.

[0199] In this modification, the urinary tract 156 is substantially fan-shaped. A probe channel 157 and a balloon channel 155 are disposed near each of the two sides of the urinary tract 156. The balloon channel 155 opens to the inside of the balloon 152.

[0200] [Variation 7-12] Figures 41B and 42 are cross-sectional views of indwelling bladder catheter 15 of variants 7-12. Figure 41B shows a cross-section at the same position as in Figure 40A. Figure 42 shows a cross-section at the same position as in Figure 40B. In this variant, shaft 153 is a multi-lumen tube having three channels: balloon channel 155, urinary channel 156, and probe channel 157.

[0201] In this modification, the urinary passage 156 has a substantially crescent-shaped cross section. A balloon passage 155 is disposed in the recessed portion of the crescent shape. A probe passage 157 having an oval cross section is disposed on the opposite side of the urinary passage 156 across the balloon passage 155. As shown in FIG. 42 , two communication passages are provided that connect the balloon passage 155 and the interior of the balloon 152.

[0202] [Variation 7-13] Figure 43 is a cross-sectional view of indwelling bladder catheter 15 of modification 7-13. Figure 44 is a view seen from arrow XLIV in Figure 43. Figure 45 is a cross-sectional view taken along line XLV-XLV in Figure 43. In this modification, shaft 153 is a multi-lumen tube having a total of four channels: urinary channel 156 and two probe channels 157.

[0203] In this modified example, the urinary path 156 has a generally concave cross section with the recess facing downward in Figure 45. One probe channel 157 is arranged in the recessed portion of the concave shape. Another probe channel 157 having a generally oval cross section and a balloon channel 155 are arranged above the urinary path 156 in Figure 45. As shown in Figure 44, the balloon channel 155 opens into a balloon water injection section 169 on the hub flexible member 22 side.

[0204] 46A is a cross-sectional view of connection hub 20 of modification 7-13. Connection hub 20 of this modification has two independent second conduits 212. First conduit 211 and two second conduits 212 are arranged to communicate with urinary tract 156 and two probe conduits 157, respectively, when indwelling bladder catheter 15 and connection hub 20 are connected.

[0205] This modification provides a measurement system 10 that can simultaneously use two measurement probes 14. The two measurement probes 14 are used by connecting them to separate measurement devices 30. The measurement device 30 may be capable of simultaneously connecting the two measurement probes 14.

[0206] One of the probe conduits 157 does not need to be connected to the urinary tract 156. A sensor that performs measurements without contacting the liquid, such as a laser flowmeter sensor, can be inserted into a conduit that does not communicate with the urinary tract 156. This provides a measurement system 10 that can simultaneously use a sensor that performs measurements while contacting the liquid using the light emitter 24 and a sensor that performs measurements without contacting the liquid.

[0207] The probe conduit 157 that is not in communication with the urinary passage 156 is an example of a non-communicating conduit in this modification. The sensor of the laser flowmeter is an example of a non-liquid-contacting sensor in this modification.

[0208] [Variation 7-14] Figure 46B is a cross-sectional view of an indwelling bladder catheter 15 of variant 7-14. Figure 46B shows a cross section at the same position as in Figure 45. In this variant, shaft 153 is a multi-lumen tube having a total of four channels: urinary channel 156 and two probe channels 157.

[0209] In this modification, the urinary tract 156 has a generally semicylindrical cross section with a straight portion disposed on the upper side in Fig. 46B. A balloon duct 155 and two probe ducts 157 are disposed on the upper side of the urinary tract 156.

[0210] [Embodiment 8] This embodiment relates to a measurement system 10 equipped with an adapter 43. Explanation of parts common to the first embodiment will be omitted.

[0211] Figure 47 is an explanatory diagram illustrating the configuration of measurement system 10 of embodiment 8. In this embodiment, indwelling bladder catheter 15 and urine collection bag 17 are directly connected without using connection hub 20. Indwelling bladder catheter 15 is a so-called three-way type having a balloon water injection section 169 and a probe port 168. Adapter 43 is attached to probe port 168. Measurement probe 14 is inserted into adapter 43 and indwelling bladder catheter 15.

[0212] Fig. 48A is a cross-sectional view of measurement probe 14 attached to adapter 43. Fig. 48B is a cross-sectional view of adapter 43. Figs. 48A and 48B are diagrams schematically showing the configurations of measurement probe 14 and adapter 43, with the longitudinal dimension of measurement probe 14 reduced.

[0213] The measurement probe 14 has an optical fiber 41 , a light emitter 24 disposed on one end face of the optical fiber 41 , and an optical fiber connector 411 connected to the other end of the optical fiber 41 .

[0214] 48B, the adapter 43 has an inner tube 435, an outer tube 436, an attachment portion 437, a retaining tube 213, a retaining rubber 214, and a retaining lid 215. An attachment portion 437 connectable to a probe port 168 is fixed to one end of the inner tube 435. The fixing structure between the probe port 168 and the outer tube 436 is, for example, a luer lock structure.

[0215] Inner tube 435 and outer tube 436 are slidable, and both ends are provided with stoppers to prevent them from coming off. Retaining tube 213, which retains retaining rubber 214, is fixed to the end of outer tube 436. Retaining lid 215 is attached to retaining tube 213. The structures of retaining tube 213, retaining rubber 214, and retaining lid 215 are the same as those in the first embodiment.

[0216] Inner tube 435 and outer tube 436 are flexible resin tubes. A separate part made of, for example, hard plastic or metal may be used as the retaining structure between inner tube 435 and outer tube 436. The retaining structure between inner tube 435 and outer tube 436 preferably has a locking mechanism (not shown) that can fix inner tube 435 in a state where it is pulled out from outer tube 436.

[0217] 48A, the measurement probe 14 is inserted into the adapter 43. The optical fiber 41 is fixed by the holding lid 215 and the holding rubber 214. When the holding lid 215 is tightened at a position where the optical fiber connector 411 abuts against the holding lid 215, the tip of the optical fiber 41 protrudes from the inner tube 435.

[0218] The measurement probe 14 is supplied to the user in a state where it is inserted into the adapter 43 as shown in Fig. 48A. Alternatively, the measurement probe 14 and the adapter 43 may be supplied separately, and the user may assemble them into the state shown in Fig. 48A.

[0219] 49 and 50 are explanatory diagrams illustrating a method of using the measurement system 10 according to the eighth embodiment. An extension fiber 42 is connected to the measurement device 30. An optical fiber receptacle 421 is provided at one end of the extension fiber 42.

[0220] The user connects measuring probe 14 and urine collection bag 17. The user inserts measuring probe 14, which is in the state described using FIG. 48A, into probe port 168. The user fixes attachment portion 437 to probe port 168. Through the above operations, indwelling bladder catheter 15 and measuring probe 14 are in the state shown in FIG. 49. At this time, measuring probe 14 is inserted halfway into shaft 153.

[0221] The user inserts the shaft 153 into the patient's urethra. Because the measurement probe 14 is not inserted into the tip side of the shaft 153, the shaft 153 is in a state where it can be easily bent, and is less likely to cause pain to the patient. With the tip of the shaft 153 inside the bladder, the user inflates the balloon 152. By inflating the balloon 152, the shaft 153 is prevented from slipping out of the urethra.

[0222] The user slides inner tube 435 and outer tube 436 to house inner tube 435 inside outer tube 436 as shown in Figure 50. This operation pushes measurement probe 14 into shaft 153, and light emitter 24 is positioned near side hole 151. Adapter 43 desirably has a locking mechanism that fixes inner tube 435 in a state where it is housed in outer tube 436. Note that adapter 43 has the same degree of flexibility as urine collection tube 172, even when inner tube 435 is housed inside outer tube 436 with measurement probe 14 inserted.

[0223] Thereafter, the user connects the optical fiber connector 411 to the optical fiber receptacle 421. With the above steps, the state shown in FIG.

[0224] The resistance when inserting measurement probe 14 into indwelling bladder catheter 15 increases as the inserted portion becomes longer. Therefore, the user needs to push measurement probe 14 with greater force as the insertion procedure nears the end. According to this embodiment, by using adapter 43, buckling and the like can be prevented in the final stage of the insertion procedure of measurement probe 14.

[0225] By using the extension fiber 42, it is possible to provide a measurement system 10 that allows the measurement device 30 to be placed at a position away from the patient's bed. The user can select and use an extension fiber 42 of an appropriate length depending on the layout of the hospital room, etc. The extension fiber 42 may be pre-connected to the optical fiber connector 411, or may be made up of the same optical fiber. This can prevent mistakes such as forgetting to connect, and also makes it possible to reduce the number of parts.

[0226] [Embodiment 9] This embodiment relates to an indwelling bladder catheter 15 to which a measuring probe 14 is fixed. Explanation of parts common to the first embodiment will be omitted.

[0227] Fig. 51 is an explanatory diagram illustrating the configuration of indwelling bladder catheter 15 of embodiment 9. Fig. 52A is an enlarged cross-sectional view of the tip of indwelling bladder catheter 15 of embodiment 9.

[0228] In this embodiment, similar to the modified example 7-4 described using Figure 29, a through hole provided in the tip member 159 communicates with the probe channel 157. Unlike the modified example 7-4, the probe channel 157 does not communicate with the urinary tract 156. The tip member 159 and the tip portion of the measuring probe 14 are adhesively fixed. The adhesive fixing part realizes the function of the fixing part in this embodiment, such as fixing the measuring probe 14 in a state where it is inserted into the probe channel 157.

[0229] That is, as shown in FIG. 51, the indwelling bladder catheter 15 of this embodiment has an optical fiber 41 to which a light emitter 24 is attached and an optical fiber connector 411 in addition to a shaft 153, a urination funnel 154, and a balloon 152.

[0230] According to this embodiment, it is possible to provide an indwelling bladder catheter 15 that can be prepared for use in a short time without the need for inserting the measuring probe 14 into the indwelling bladder catheter 15.

[0231] [Variation 9-1] 52B is an enlarged cross-sectional view of the tip of indwelling bladder catheter 15 of variation 9-1. In this variation, support 158 ​​is fixed to the tip of indwelling bladder catheter 15. Support 158 ​​supports plate-shaped light-emitting body 24. Light-emitting body 24 is disposed at an angle to the central axis of indwelling bladder catheter 15, and seals the tip of probe conduit 157. The end face of optical fiber 41 is polished at an angle and abuts against light-emitting body 24.

[0232] 53A to 54 are explanatory diagrams illustrating the assembly procedure for indwelling bladder catheter 15 of variation 9-1. Note that the procedures other than fixing light-emitting body 24 and optical fiber 41 are the same as those for assembling conventional indwelling bladder catheter 15, and therefore will not be described here.

[0233] The shaft 153 is a multi-lumen tube having three channels: a urinary channel 156, a probe channel 157, and a balloon channel 155. As shown in Fig. 53A, the wall between the urinary channel 156 and the probe channel 157 is removed at the tip of the shaft 153.

[0234] As shown in Fig. 53B, the tip of probe conduit 157 is sealed by light emitter 24 fixed to support 158. As shown in Fig. 54, optical fiber 41, the tip of which is polished at an angle, is inserted into probe conduit 157. A light-transmitting adhesive is applied to the tip of optical fiber 41, and optical fiber 41 and light emitter 24 are adhesively fixed together.

[0235] Thereafter, tip member 159 is inserted into the tip of indwelling bladder catheter 15 and fixed with adhesive. In this way, indwelling bladder catheter 15 of this modified example is completed.

[0236] [Embodiment 10] 55 is a functional block diagram of a measurement system 10 according to a tenth embodiment. The measurement system 10 includes a measurement probe 14 and a measurement device 30. The measurement probe 14 includes an elongated body 41 that can be inserted into a catheter 15 having a flow path 156, a sensor 24 that is fixed to the elongated body 41 and can detect the state of the fluid flowing through the flow path 156, and a sensor holder 141 that holds the sensor 24 in a predetermined position when the elongated body 41 is inserted into the catheter 15.

[0237] The measuring device 30 includes a data acquisition unit 81 that acquires data from the sensor 24 held by the sensor holding unit 141, a determination unit 82 that determines the condition of the patient in whom the catheter 15 is placed based on the acquired data, and a display unit 83 that displays the determined condition.

[0238] The technical features (constituent elements) described in each embodiment can be combined with each other, and by combining them, new technical features can be formed. The embodiments disclosed herein are to be considered as illustrative in all respects and not restrictive. The scope of the present invention is defined by the claims, not by the above meaning, and is intended to include all modifications within the meaning and scope of the claims. [Explanation of symbols]

[0239] 10 Measurement System 14 Measuring probe 141 Housing (sensor holding part) 142 Coil (sensor holder) 143 Cover plate (sensor holding part) 144 Wire (sensor holding part) 146 Coil holder 147 Holding Tube 148 Protective tube 15 Indwelling bladder catheter (catheter) 151 Side hole (opening) 152 Balloon 153 Shaft 154 Urinary funnel 155 Balloon Pipeline 156 Urinary tract (flow path) 157 Probe Pipe 158 Support 159 Tip member (anti-protrusion part) 168 probe ports 169 Balloon Water Injection Section 17 Urine collection bag 171 Bags 172 Urine collection tube 173 Connecting tube 20 Connection Hubs 21 Hub rigid member 211 1st pipeline 212 2nd pipeline 213 Holding tube 214 Retaining rubber 215 Holding lid 216 Tapered section 218 Catheter connection part 22 Hub flexible member 228 Urine collection bag connection part 24 Light emitter (sensor) 241 First Light-Emitting Body 242 Second Light-Emitting Body 244 Non-luminous part 245 Luminous Ring 246 Luminous Block 248 Light guide section 249 Adhesive layer 30 Measuring Equipment 31 Control Unit 32 Main storage 33 Auxiliary storage device 34 Communications Department 35 Display section 36 Input section 371 First Connector 372 Second Connector 373 Third Connector 41 Optical fiber (long body) 411 Fiber Optic Connector 413 Fluorescent Connector 414 Irradiation Optical Connector 42 Extension Fiber 421 Fiber Optic Receptacle 43 Adapter 435 Inner cylinder 436 Outer Cylinder 437 Mounting part 45 Temperature Sensor 49 Fasteners 491 1st part 492 2nd Part 496 Urine collection tube holder 497 Optical fiber holder 51 Light source 52 Optical analyzer 521 1st optical analyzer 522 2nd optical analyzer 55 Light guide 56 Beam Splitter 561 First beam splitter 562 Second beam splitter 57 Filters 61 Date and time field 62 Oxygen Partial Pressure Column 63 Temperature column 67 Indicator column 68 Graph column 81 Data Acquisition Section 82 Judgment section 83 Display section

Claims

1. A catheter set comprising a catheter and a measurement probe, The catheter comprises: An opening provided on the tip side; a flow path provided between the opening and a rear end side; a probe conduit arranged parallel to the flow path; the measuring probe has a light guide that can be inserted into the probe conduit; The catheter further includes a protrusion prevention portion that prevents the light guide from protruding from the distal end side of the probe conduit. Catheter set.

2. the probe conduit includes a communication passage communicating with the flow path; The measuring probe is fixed to the light guide and includes a sensor capable of detecting the state of the fluid flowing through the communication passage. The catheter set according to claim 1 .

3. The catheter is provided with a sensor disposed between the flow path and the probe conduit, and capable of detecting the state of the fluid flowing through the flow path. The catheter set according to claim 1 .

4. the probe channel opens at the distal end side of the catheter, The measuring probe is fixed to the light guide and includes a sensor capable of detecting the state of the fluid flowing through the flow path. The catheter set according to claim 1 .

5. The sensor includes a light emitter that emits light when it comes into contact with a component to be measured, The light guide guides the light emitted from the light emitter. The catheter set according to any one of claims 2 to 4.

6. The emitted light is fluorescent light The catheter set according to claim 5.

7. The light-emitting body changes its light-emitting state in response to the partial pressure of oxygen in the fluid, the partial pressure of carbon dioxide in the fluid, the hydrogen ion exponent of the fluid, the amount of potassium ions in the fluid, the amount of sodium ions in the fluid, the amount of chloride ions in the fluid, or the temperature of the fluid. The catheter set according to claim 5 or 6.

8. The sensor has a plurality of light emitters corresponding to a plurality of measurement items. The catheter set according to any one of claims 5 to 7.

9. The measuring probe is provided with a fixing portion that can fix the measuring probe in a state where the measuring probe is inserted into the probe conduit. The catheter set according to any one of claims 1 to 8.

10. The fixing portion seals the gap between the measurement probe and the probe conduit. The catheter set according to claim 9.

11. the catheter is an indwelling bladder catheter, a urine collection bag connected to the indwelling bladder catheter, A fastener is provided for fastening the measurement probe to the surface of the urine collection bag. The catheter set according to any one of claims 1 to 10.

12. A catheter set comprising a catheter and a measurement probe, The catheter comprises: An opening provided on the tip side; a flow path provided between the opening and a rear end side, the flow path including a large diameter portion disposed at the opening, a small diameter portion disposed at the rear end side, and a tapered portion disposed between the large diameter portion and the small diameter portion; The measuring probe has a sensor disposed in the tapered portion. Catheter set.

13. The large diameter portion is provided with a check valve The catheter set of claim 12.

14. A measurement system comprising a catheter, a measurement probe, and a measurement device, The catheter comprises: An opening provided on the tip side; a flow path provided between the opening and a rear end side; a probe conduit arranged parallel to the flow path; the catheter or the measuring probe has a sensor capable of detecting the state of the fluid flowing through the flow path, the catheter further has a protrusion prevention part that prevents the tip of the measuring probe from protruding from the tip side of the probe conduit, The measuring device is a data acquisition unit that acquires data from the sensor via the measurement probe held in the probe conduit by the protrusion prevention unit; a display unit that displays information about the patient in whom the catheter is placed based on the acquired data. Measurement system.

15. The sensor has a light-emitting body that emits light when it comes into contact with a component to be measured, the measurement probe has a light guide that guides the radiated light emitted from the light emitter, The measuring device is a light source that irradiates the light emitter with excitation light via the light guide; a light receiving unit that receives the emitted light guided by the light guide; an optical analyzer that analyzes the emitted light, The data acquisition unit acquires data relating to the light emission state of the light emitter from the light analyzer.

15. The measurement system of claim 14.

16. a light shield that prevents light other than the emitted light from entering the light guide; 16. The measurement system of claim 15.

17. The luminous body changes its luminous state in response to the partial pressure of oxygen in the fluid, the partial pressure of carbon dioxide in the fluid, the hydrogen ion exponent of the fluid, the amount of potassium ions in the fluid, the amount of sodium ions in the fluid, the amount of chloride ions in the fluid, or the temperature of the fluid.

17. The measurement system according to claim 15 or claim 16.

18. The emitted light is fluorescent light 18. A measurement system according to any one of claims 15 to 17.

19. the sensor has a plurality of light-emitting bodies corresponding to a plurality of measurement items, The light guide guides the light emitted from the plurality of light emitters in a mixed state.

19. A measurement system according to any one of claims 15 to 18.

20. the sensors are plural; The light guide guides the light emitted from the light emitters of the plurality of sensors in a mixed state.

20. A measurement system according to any one of claims 15 to 19.

21. The measuring device is a spectroscopic unit that spectroscopically separates the emitted light; a plurality of optical analyzers for analyzing the respective light beams separated by the spectroscopic unit; 21. A measurement system according to claim 19 or claim 20.

22. The measuring device is a filter that transmits a specific band of the emitted light; The optical analyzer analyzes the light transmitted through the filter.

21. A measurement system according to claim 19 or claim 20.

23. the catheter has a non-communicating duct that is arranged parallel to the flow path and does not communicate with the flow path; a non-liquid-contact sensor inserted into the non-communicating pipe line; 23. A measurement system according to any one of claims 14 to 22.

24. The non-wetted sensor is a laser flowmeter sensor.

24. The measurement system of claim 23.

Images